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so definitely this game has been shown to be effective so far. | H | 5 | 4.8 | 4.4 | 1533 | Male |
this could be a game that classes do together. | H | 5.2 | 5.4 | 5.2 | 1533 | Male |
i am hoping that more students can use this game and they can also kind of prepare themselves for when schools do reopen in [inaudible 00:04:41] on how to keep- | X | 3.6 | 5 | 4.2 | 1533 | Male |
... still very ambitious and i'm going to continue again keeping this resource safe and accessible to everybody. | C | 4.8 | 4 | 3.8 | 1533 | Male |
as for dr. pixel, he's going to keep evolving again with the changing times and keep bringing new knowledge and new content for people to play and enjoy. i my- | H | 5.2 | 4.8 | 5 | 1533 | Male |
... yeah, that's the career goal. and i guess this game and this cause also falls directly in line of- | H | 4.8 | 3.8 | 4.8 | 1533 | Male |
... so for sure. one thing that i do want to say because this is a campus based podcast and to all my peers out there is when i was first id- | N | 3.6 | 4.4 | 4.4 | 1533 | Male |
... if you do have an idea like this or like anything similar- | N | 3.8 | 3.6 | 3.6 | 1533 | Male |
... and yeah, i would like to definitely give a huge thank you to dr. nissimov and the- | H | 4.4 | 5 | 4.4 | 1533 | Male |
and mask up when headed indoors in public spaces. | N | 4.6 | 4.2 | 4.6 | 1533 | Male |
give us an interview idea or you can't find the show notes. we keep talking about. | H | 4.8 | 4.8 | 4.8 | 1533 | Male |
an update to the university's executive council last week- | X | 4.8 | 4.4 | 4.6 | 1533 | Male |
... the president outlined how these meetings are helping to shape the way the university moves ahead and that this work must involve the leadership, advice and reflections of people with- | N | 4.8 | 4.8 | 4.8 | 1533 | Male |
... experiences of racism. charmaine dean- | N | 4.2 | 3.8 | 3.8 | 1533 | Male |
... will help lead a consultative approach to listening to individuals and groups on campus. | H | 4.4 | 5.2 | 4.8 | 1533 | Male |
university leaders will continue meeting with individuals and groups to listen to their feedback on ways the university will work to address racism. | X | 5.2 | 4.6 | 4.8 | 1533 | Male |
... library remains closed as part of the university's response to the global pandemic. | N | 4 | 3.8 | 4.6 | 1533 | Male |
but while the closure limits access to hard copies of the highlighted titles- | H | 5 | 5 | 4.8 | 1533 | Male |
... several electronic books appear on the list and you can access them online. | X | 4.6 | 5 | 4.8 | 1533 | Male |
if you've been approved to return to campus or to enter any university buildings you need- | N | 5.2 | 4.8 | 4.8 | 1533 | Male |
research labs are considered employee only spaces for the time being. | N | 4.6 | 4 | 4.4 | 1533 | Male |
supervisors will set the expectation with their teams based on the physical setup of the lab and the activities taking place therein. | H | 5 | 5 | 5 | 1533 | Male |
... if the ability to see the mouth is essential for communication. | N | 4.4 | 4 | 4.6 | 1533 | Male |
university is getting ready to welcome our students back for a new school year- | H | 4 | 4.8 | 4.2 | 1533 | Male |
... while for most of them this will mean studying remotely. | N | 4.4 | 4.2 | 4.2 | 1533 | Male |
we do expect to welcome a number of students back to campus physically. | H | 5 | 5 | 5 | 1533 | Male |
the goal of the checklist is to help students prepare to travel internationally and meet mandatory 14 day quarantine or- | H | 5.8 | 5.2 | 5.8 | 1533 | Male |
... highlights of the checklist include a guide for students to develop their own quarantine plan- | X | 4.6 | 5 | 4.8 | 1533 | Male |
if you'd like to take an active role in welcoming our students back- | H | 4.6 | 5.2 | 4.8 | 1533 | Male |
... tears move in will take place between august 24th- | H | 4.4 | 5 | 5.2 | 1533 | Male |
you can help our students feel safe and connected to campus when they arrive. | H | 4 | 4.8 | 4.4 | 1533 | Male |
so that could include computer upgrades and equipment such as the monitor- | H | 5 | 5.2 | 5 | 1533 | Male |
the deadline to apply for the academic readiness bursary is september 30th. | N | 5 | 4.2 | 4.6 | 1533 | Male |
and as he tells pamela, the work could help in the development of a vaccine. | H | 5 | 5.4 | 5.2 | 1533 | Male |
which looks at the immune system and the ways that it can protect an organism against infection, right? | C | 4 | 4.2 | 4.6 | 1533 | Male |
it's complicated. but, one of the main ways you defend against viruses is you produce antibodies with- | N | 4.8 | 4.4 | 4.6 | 1533 | Male |
almost like saran wrap and then the virus is prevented from sticking to your cells because it's all wrapped up and coded. | X | 4.4 | 4.6 | 4.8 | 1533 | Male |
the antibodies also work as a target for other mechanisms you have that will kill the virus. | X | 4.6 | 4.8 | 4.6 | 1533 | Male |
particularly the macrophages which are like ameboid cells that chew it up and kill it. | X | 4.8 | 3.8 | 5 | 1533 | Male |
now your focus has been primarily fish and specifically the species of fish that we eat. | X | 5 | 4.8 | 4.6 | 1533 | Male |
for one thing, we don't catch anymore fish from the ocean in terms of tons of animals than we did in 1993- | N | 4.2 | 3.8 | 4.6 | 1533 | Male |
... which is a very important protein source for much of the third world, and is a very nutritious and healthy alternative for people- | H | 4.8 | 5.2 | 5.2 | 1533 | Male |
... the fish that the world eats is comes from fish farms- | N | 4.4 | 4 | 4 | 1533 | Male |
because i'm an immunologist, i'm interested in the health of the fish. so- | C | 4.8 | 4.2 | 5.2 | 1533 | Male |
... finding families of fish that respond better in certain situations- | N | 5 | 3.8 | 4.4 | 1533 | Male |
... looking at it from the outside until it's pretty much diseased and dead. | N | 4 | 4 | 4.2 | 1533 | Male |
so antibiotics are quite often used in fish because vaccines aren't always effective. and rather than dump antibiotics into the ocean- | N | 4.2 | 3.8 | 4.6 | 1533 | Male |
... molecules that we can actually use as treatments to reduce that antibiotic use. | X | 4.6 | 4.8 | 4.6 | 1533 | Male |
and are fish in fish farms more susceptible to disease than wild stock? | C | 3 | 3.2 | 4.2 | 1533 | Male |
it's hard to say whether they get more than say pigs or cattle or chicken would get- | X | 4.8 | 3.2 | 5 | 1533 | Male |
... well, like everybody, we were locked down and forced to work from home and- | N | 4.8 | 3.4 | 4.4 | 1533 | Male |
... so it has slowed the fish research down a lot. | H | 5.2 | 4.4 | 5.2 | 1533 | Male |
but now you're testing the blood of people. you're not working with fish, how- | U | 4.4 | 4 | 5.4 | 1533 | Male |
what can you do, basically? what can you do to help us in any way, shape or form? so- | H | 4.8 | 5 | 5 | 1533 | Male |
... yeah, one of only two immunologists on campus. | N | 4.6 | 4.6 | 4.4 | 1533 | Male |
it involved a lab from new york, a medical school, and they had to supply us with a couple of little chemical reagents- | N | 4 | 4.6 | 4.4 | 1533 | Male |
... and they gave us the reagents. so very quickly we were able to ramp up because we had the equipment and because... i'm actually very fortunate that i ha- | H | 5.4 | 5.2 | 4.6 | 1284 | Female |
... measuring the immune status of fish and measuring molecules in fish blood- | X | 4.8 | 3.2 | 4.6 | 1538 | Female |
and to be honest, substituting fish blood for human blood in these assays is not that complicated. | N | 4.4 | 4.6 | 4.2 | 1538 | Female |
... anything else so people don't wander in and out and it's a room where you're especially clean and you have- | N | 4.2 | 3.2 | 4.6 | 1538 | Female |
correct, but coronaviruses, the type of virus that covid 19 is caused by are not very prevalent in blood. they- | X | 4.4 | 4.4 | 4.8 | 1538 | Female |
... need a level four lab like they have in winnipeg to handle it. | N | 4.8 | 3.2 | 4.6 | 1538 | Female |
i see, okay. and what are you looking for in these human blood samples? | N | 4.6 | 3.8 | 4 | 1538 | Female |
so we're looking for those specific antibodies that respond to the sars-cov-2 virus. | X | 4.2 | 4.8 | 4.6 | 1538 | Female |
and it's pretty easy to do because we have a recombinant protein- | X | 4.6 | 4.6 | 4.6 | 1538 | Female |
... just a piece of the protein from the virus we put on a really a plastic plate. | N | 4.6 | 4.4 | 4.6 | 1538 | Female |
ideally it would tell us that they're now immune. | N | 4.6 | 4.6 | 4.2 | 1538 | Female |
but to be honest the literature is very unclear on whether people get sick a second time. | U | 4.4 | 3.4 | 5 | 1538 | Female |
... on it. so we're hoping that people are immune if they have antibodies. | C | 4.2 | 4.4 | 4.8 | 1538 | Female |
but the samples i'm doing right now just because we are getting the assay up and running are from people that my partners know have either been sick or have- | N | 4.8 | 3.2 | 4.4 | 1538 | Female |
... sick and which ones were people who had never been or at least not shown symptoms of the virus and we had to predict, ourselves, what they were like. | O | 5.2 | 3.6 | 4.8 | 1538 | Female |
so it may be that this person was infected just very quickly before we took the blood sample. | X | 4.6 | 4.2 | 4.2 | 1538 | Female |
well it could be for many things. it could be to screen to make sure that they've been exposed so that if there is any research that shows their- | C | 5 | 4.6 | 4 | 1538 | Female |
... and one of the things in the immune response you would look for is antibodies. | N | 3.4 | 4.2 | 4 | 1538 | Female |
if they have antibodies, does that automatically mean that they're immune? | X | 4.8 | 4.6 | 4.6 | 1538 | Female |
... haven't had enough time to test that because what has to happen is you have to develop antibodies and then get exposed to the virus again. | X | 4.8 | 3.6 | 4.4 | 1538 | Female |
and so you have to wait and see if people who have antibodies actually developed the illness again. and- | N | 4.4 | 3.2 | 4.4 | 1538 | Female |
but this flip side of that is not too many people have got the disease. | X | 4.2 | 3.8 | 4.2 | 1538 | Female |
i would say less than half the amount of some of the other people. | N | 3.6 | 3.6 | 4.6 | 1538 | Female |
and that's the real question, why we don't want to say people have antibodies are immune because we don't know what level you need on that. and it will take a- | X | 4.8 | 3.6 | 4.6 | 1538 | Female |
but we'll have to see whether the antibodies really do confer protection, i think. | O | 4 | 4.4 | 4 | 1538 | Female |
... work you've done and from what you know about the immune system. | N | 5 | 4.4 | 4.6 | 1538 | Female |
the simplest one is the flu vaccine. | N | 3.6 | 3.6 | 3.6 | 1538 | Female |
where the particular protein on the virus that helps it get in our cells is called the spike protein. it's- | H | 4.4 | 4.4 | 4.6 | 1538 | Female |
right.so you could just take that protein- | X | 4 | 4.6 | 4 | 1538 | Female |
... inject people. now the experience with coronavirus says that doesn't work particularly well- | N | 5 | 3.6 | 4.8 | 1538 | Female |
a harmless virus that infects people all the time but doesn't cause disease. | U | 4.2 | 4.6 | 4.6 | 1538 | Female |
they inject that in you because of course viruses replicate in our cells, they- | N | 4.8 | 3.4 | 5.2 | 1538 | Female |
... they're sort of novel technologies that we're scrambling to get going now. | N | 3.6 | 4.6 | 4.4 | 1538 | Female |
and the other thing it's going to have to elicit is something i'm not testing for but- | N | 4 | 3.2 | 4.4 | 1538 | Female |
.. we have another type of cell in our body called a killer t cell. | N | 3.2 | 3.2 | 4 | 1538 | Female |
... always side effects. and that's why i think the russian vaccine is a bit premature because they haven't tested that. | N | 4.8 | 3.6 | 4.6 | 1538 | Female |
we'll probably take until next march because it takes a lot of time to test all those things carefully. | X | 3.6 | 4 | 4 | 1538 | Female |
well what we do know about coronaviruses is they don't elicit long lasting immunity. | N | 4.6 | 4.2 | 4.8 | 1538 | Female |
so the type of immunity they illicit is short lived. for some of the other coronaviruses like sars and mers, the antibodies only last months to a year or two. | U | 4.8 | 4.4 | 4 | 1538 | Female |
... measles where you can have one boost and you're good for life. | N | 3.2 | 4.8 | 4.2 | 1538 | Female |
the problem is a lot of that discussion that scientists have happens behind the scenes. | A | 4.6 | 3.2 | 4.8 | 1538 | Female |
we discuss what's happening with a research paper and it's what's called peer reviewed. many- | C | 4 | 3.4 | 4.2 | 1538 | Female |
what's happening right now is everyone's so desperate for information that the instance someone does an experiment- | X | 3.8 | 2.8 | 4.4 | 1538 | Female |
they're releasing it to the public without that peer review, that self-check- | N | 4 | 3.8 | 4 | 1538 | Female |
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