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1,700 | 821 | Failure of T cell receptor-anti-CD3 monoclonal antibody interaction in T cells from marrow recipients to induce increases in intracellular ionized calcium.
There are multiple immune defects in T cells from recipients after bone marrow transplantation (BMT).
This study examines recipient T cells for increases in intra... | C20 |
1,701 | 5,890 | Interferon system and natural killer cell activity in myasthenia gravis.
The autoimmune response in myasthenia gravis is well characterized, but little is known about the mechanisms initiating it.
We have studied the interferon system and natural killer cell activity in 25 patients with myasthenia gravis and compared... | C20 |
1,702 | 851 | Incidence of cutaneous T cell lymphoma and other rare skin cancers in a defined population.
Between 1970 and 1984 in Rochester, Minnesota, rare skin cancers developed in 15 local residents: cutaneous T cell lymphoma (six subjects), dermatofibrosarcoma protuberans (four), adenocarcinoma of sweat glands (two), Merkel ce... | C20 |
1,703 | 5,387 | The agent of bacillary angiomatosis. An approach to the identification of uncultured pathogens
BACKGROUND.
Bacillary angiomatosis is an infectious disease causing proliferation of small blood vessels in the skin and visceral organs of patients with human immunodeficiency virus infection and other immunocompromised h... | C20 |
1,704 | 6,133 | The prevalence of antibody to HTLV-I/II in United States plasma donors and in United States and French hemophiliacs.
Antibody to HTLV-I/II was detected in 19 (0.3%) of 6286 plasma donors from five regions of the United States (US).
This seroprevalence rate is approximately 10 times that in whole blood donors.
The re... | C20 |
1,705 | 9,696 | Massive hepatic infarction in systemic lupus erythematosus.
Liver disease in systemic lupus erythematosus, as demonstrated by abnormal histopathology, is rare and usually mild; typically, this hepatic disease is of chronic nature and not related to a hypercoagulable state.
A patient is described in whom life-threaten... | C20 |
1,706 | 9,662 | Amyloidosis associated bleeding diatheses in the surgical patient.
The coagulopathies associated with amyloidosis have not been widely appreciated.
We encountered a patient with amyloidosis and mildly abnormal coagulation studies who presented for an emergency laparotomy for acute bowel obstruction.
Upon gentle mani... | C20 |
1,707 | 7,747 | A study of immunoglobulin G in the cerebrospinal fluid of 1007 patients with suspected neurological disease using isoelectric focusing and the Log IgG-Index. A comparison and diagnostic applications.
Cerebrospinal fluid and serum immunoglobulin G from 1007 patients with suspected neurological disease were analysed by ... | C20 |
1,708 | 8,806 | Primary malignant lymphomas of the spleen. A morphologic and immunohistochemical analysis of 17 cases.
Seventeen cases of primary malignant lymphoma of the spleen (PMLS) were identified among 500 splenectomy specimens showing involvement by Hodgkin's disease or non-Hodgkin's lymphoma.
All PMLS represented non-Hodgkin... | C20 |
1,709 | 3,183 | Full-length recombinant CD4 and recombinant gp120 inhibit fusion between HIV infected macrophages and uninfected CD4-expressing T-lymphoblastoid cells.
Human immunodeficiency virus-(HIV) infected monocyte-macrophages may contribute to the pathogenesis of HIV-associated immune deficiency and dysfunction by acting as a ... | C20 |
1,710 | 8,330 | The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air
BACKGROUND.
The enzyme 5-lipoxygenase catalyzes the metabolism of arachidonic acid to form products that have been implicated in the airway obstruction of asthma.
We hypothesized that if products of the 5-lipoxygenase pathway are important... | C20 |
1,711 | 3,366 | An anonymous seroprevalence survey of HIV infection among pregnant women in British Columbia and the Yukon Territory
We performed an anonymous seroprevalence survey of human immunodeficiency virus (HIV) type 1 infection through HIV antibody testing of blood samples from 22,512 women aged 15 to 44 years receiving pren... | C20 |
1,712 | 5,340 | Disseminated histoplasmosis in the acquired immune deficiency syndrome: clinical findings, diagnosis and treatment, and review of the literature.
Histoplasmosis is a serious opportunistic infection in patients with AIDS, often representing the first manifestation of the syndrome.
Most infections occurring within the ... | C20 |
1,713 | 940 | Repeated exposure of asthmatic airways to inhaled adenosine 5'-monophosphate attenuates bronchoconstriction provoked by exercise.
Inhaled adenosine 5'-monophosphate (AMP) induces bronchoconstriction in subjects with asthma, probably caused by histamine release from airway mast cells, and repeated AMP bronchial challen... | C20 |
1,714 | 6,672 | Effect of education on the use of universal precautions in a university hospital emergency department.
STUDY OBJECTIVES: To determine if an educational program would improve both knowledge and practice of universal precautions by nursing personnel.
DESIGN: Participants were given a 14-question test and observed for t... | C20 |
1,715 | 689 | Amyloid deposition in intrahepatic large bile ducts and peribiliary glands in systemic amyloidosis.
Amyloid deposition in the hepatic parenchyma and portal tracts in the liver is well known in systemic amyloidosis.
We recently experienced an autopsy case of systemic amyloidosis presenting the amyloid deposits in the ... | C20 |
1,716 | 7,640 | Diagnosis of mold allergy by RAST and skin prick testing.
Sera from 33 patients with mold allergy proven by bronchial provocation were analyzed for specific IgE against six mold species comparing an improved Phadebas RAST with four other techniques.
The new method was more sensitive and gave significantly higher IgE ... | C20 |
1,717 | 8,375 | The immunology of HIV disease and pregnancy and possible interactions.
HIV infection may impair a large portion of the human immune response.
Infection of CD4+ T cells results in depletion of this population, leading to dysfunction of T-cell-dependent activities.
Numerous other immune functions are directly or indir... | C20 |
1,718 | 6,381 | A double-blind, placebo-controlled trial of intravenous immunoglobulin therapy in patients with chronic fatigue syndrome
PURPOSE: The chronic fatigue syndrome (CFS) is characterized by profound fatigue, neuropsychiatric dysfunction, and frequent abnormalities in cell-mediated immunity.
No effective therapy is known.... | C20 |
1,719 | 7,044 | Willingness of health-professions students to treat patients with AIDS.
This 1988-89 survey of 319 students in the medical, dental, nursing, and allied health-care professions revealed that over one-third had some reservations about treating acquired immunodeficiency syndrome (AIDS) patients.
Most were unwilling to p... | C20 |
1,720 | 7,039 | Medical and dental students' attitudes about the AIDS epidemic.
This study investigated changes, over a one-year period, in medical and dental students' attitudes toward various issues related to contact with AIDS patients.
In 1988 and 1989, the authors surveyed second- and third-year medical and dental students at o... | C20 |
1,721 | 4,592 | Immunology of AIDS related to psoriasis.
The association of severe psoriasis with HIV infection, which dysregulates and destroys the human immune system, supports the hypothesis that psoriasis is an immunologically mediated disease.
Psoriasis and Kaposi's sarcoma share angiogenesis as basic early findings and could b... | C20 |
1,722 | 8,504 | Bronchoalveolar lavage via a modified stomach tube in intubated patients with the acquired immunodeficiency syndrome and diffuse pneumonia.
A simple non-bronchoscopic bronchoalveolar lavage method was used in 30 patients with the acquired immunodeficiency syndrome undergoing assisted ventilation for respiratory failur... | C20 |
1,723 | 7,267 | The HIV cytopathic effect: potential target for therapy?
HIV kills activated infected CD4+ T cells after a burst of replication and the release of large numbers of virions.
From a review of the literature on HIV regulatory genes and from preliminary mathematical models of HIV dynamics at four levels (host population ... | C20 |
1,724 | 6,559 | High incidence of viral hepatitis among American missionaries in Africa.
Protestant missionaries (n = 360) serving in sub-Saharan Africa between 1967-1984 were studied to determine the risk of hepatitis A virus (HAV) and hepatitis B virus (HBV) infection.
Personnel were serologically screened for antibody to both the... | C20 |
1,725 | 7,714 | Vitreous amyloidosis associated with homozygosity for the transthyretin methionine-30 gene.
Familial amyloidotic polyneuropathy is an autosomal dominant inherited disorder.
Biochemical studies have revealed that the amyloid protein in familial amyloidotic polyneuropathy of Japanese, Swedish, and Portuguese origin mai... | C20 |
1,726 | 2,605 | Bacterial lipopolysaccharide transforms mesangial into proliferative lupus nephritis without interfering with processing of pathogenic immune complexes in NZB/W mice.
Systemic lupus erythematosus is a multifactorial systemic disease in which genetic, immunologic, hormonal, and environmental factors may contribute to d... | C20 |
1,727 | 3,179 | Cytotoxic activity against HIV-infected monocytes by recombinant interleukin 2-activated natural killer cells.
Natural killer (NK) cells have long been known to aid in the control of viral infections by killing virus-infected cells, including those infected with human immunodeficiency virus (HIV).
Among the possible ... | C20 |
1,728 | 8,309 | Genital herpes simplex virus infections.
There has been a dramatic increase in patient visits to physicians for evaluation and treatment of genital herpes infections.
This has resulted in part from an increase in genital herpes infections, particularly severe, first-episode genital herpes infections in adults without... | C20 |
1,729 | 886 | Itraconazole in opportunistic mycoses: cryptococcosis and aspergillosis.
Striking results were obtained with oral itraconazole therapy in two opportunistic mycoses.
Of 28 patients with cryptococcal meningitis, 18 achieved complete responses, including 16 of 24 patients with acquired immunodeficiency syndrome.
Other ... | C20 |
1,730 | 4,559 | A small proportion of cationic antibodies in immune complexes is sufficient to mediate their deposition in glomeruli.
Positively charged antibodies mediate enhanced deposition of circulating immune complexes at the glomerular basement membrane.
The presented experiments demonstrate that when soluble immune complexes ... | C20 |
1,731 | 8,328 | Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia.
BACKGROUND and METHODS.
We describe five patients with underlying neoplasms in whom painful mucosal ulcerations and polymorphous skin lesions developed, usually with progression to blistering eruptions on the trunk and extremitie... | C20 |
1,732 | 2,391 | Anaplastic large cell (Ki-1) lymphoma with histiocytic phenotype simulating carcinoma.
Histiocytic and epithelial cell types share many cytomorphologic and functional characteristics; it is predictable, therefore, that corresponding malignancies might be difficult to distinguish.
Described is the case of a 52-year-ol... | C20 |
1,733 | 6,315 | Racial, social, and environmental risks for childhood asthma.
Unlike a number of childhood problems, it is not clear that there are racial or socioeconomic disparities in the prevalence of childhood asthma.
We analyzed data from the Child Health Supplement to the 1981 National health Interview Survey, a population-ba... | C20 |
1,734 | 223 | Human T-cell leukemia virus type 1 associated with small cell lung cancer.
A patient with small cell lung cancer (SCLC) whose serum contained high levels of soluble interleukin-2 receptors is reported.
Soluble interleukin-2 receptors in the supernatant of cultured SCLC cells obtained from the patient's pleural effusi... | C20 |
1,735 | 7,273 | Relapse from safer sex: the next challenge for AIDS prevention efforts.
Prevention campaigns to reduce sexual transmission of human immunodeficiency virus (HIV) typically emphasize the initial adoption of safer sex techniques.
We present data from a 5-year prospective study to show that the vast majority of resident ... | C20 |
1,736 | 5,245 | Diagnosis of malignant cardiac disease by endomyocardial biopsy
Among oncology patients, endomyocardial biopsy has been used primarily for the evaluation of anthracycline cardiotoxicity.
In addition, however, endomyocardial biopsy may be useful for the detection of malignant cardiac neoplasms.
Between 1982 and 1989... | C20 |
1,737 | 7,207 | Mapping of a functional autoimmune epitope on the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy.
The presence and properties of serum autoantibodies against beta-adrenergic receptors in patients with idiopathic dilated cardiomyopathy were studied using synthetic peptides derived from th... | C20 |
1,738 | 9,354 | Lymphoproliferative disorders associated with carbamazepine.
Carbamazepine-induced lymphoproliferative disorders are relatively rare.
A 32-year-old woman developed cervical lymphadenopathy while taking carbamazepine.
Histologic evaluation of the lymph node biopsy specimen demonstrated near-total effacement of the no... | C20 |
1,739 | 9,369 | Stereotactic biopsy of an active multiple sclerosis lesion. Immunocytochemical analysis and neuropathologic correlation with magnetic resonance imaging.
Stereotactic biopsy of an active multiple sclerosis lesion in a 23-year-old patient with unilateral symptoms and an isolated high-signal-intensity magnetic resonance ... | C20 |
1,740 | 4,330 | Autoimmunity and malignancy.
In patients with autoimmune diseases malignancy is observed more frequently than in an age-matched control group.
In strains of mice susceptible to autoimmune diseases, the incidence of lymphoreticular malignancies is increased.
Although viruses have not been directly implicated in their... | C20 |
1,741 | 5,599 | The prevalence of cardiac valvular pathosis in patients with systemic lupus erythematosus.
The purpose of this study was to determine the prevalence of valvular pathosis in a population of patients with SLE, to assess the candidacy of such patients for antibiotic prophylaxis before dental treatment.
The hospital reco... | C20 |
1,742 | 9,291 | Comparative airway response to inhaled bradykinin, kallidin, and [des-Arg9]bradykinin in normal and asthmatic subjects.
Bradykinin, kallidin (lys-bradykinin), and [des-Arg9]bradykinin are oligopeptides that may contribute as mediators in the pathogenesis of asthma by interacting with specific receptors designated B1 a... | C20 |
1,743 | 8,401 | Selective induction of toxicity to human cells expressing human immunodeficiency virus type 1 Tat by a conditionally cytotoxic adenovirus vector.
The human immunodeficiency viruses (HIVs) primarily infect CD4+ T lymphocytes, leading eventually to the development of a systemic immune dysfunction termed acquired immunod... | C20 |
1,744 | 4,949 | Dideoxycytidine alone and in an alternating schedule with zidovudine in children with symptomatic human immunodeficiency virus infection.
OBJECTIVE: To determine whether a short course of 2',3'-dideoxycytidine (ddC) could provide safe antiretroviral activity in children with symptomatic human immunodeficiency virus in... | C20 |
1,745 | 6,386 | Beta 2-microglobulin predicts survival in primary systemic amyloidosis.
PURPOSE: The study assessed whether beta 2-microglobulin levels predict survival or response in patients with primary systemic amyloidosis without associated multiple myeloma.
PATIENTS AND METHODS: The study group consisted of 131 untreated patie... | C20 |
1,746 | 9,408 | An analysis of the economic impact of HIV infection among patients at Mama Yemo Hospital, Kinshasa, Zaire.
In a prospective study of adult admissions to the Department of Internal Medicine at Mama Yemo Hospital, Kinshasa, Zaire in late 1988, 129 women and 122 men were screened for HIV infection.
Fifty per cent were f... | C20 |
1,747 | 9,169 | Helicobacter pylori infection in patients with acquired immune deficiency syndrome.
A controlled study was conducted on patients with human immunodeficiency virus (HIV) infection referred for upper endoscopy to evaluate the prevalence of Helicobacter pylori (H.
pylori) infection.
Four different stains and culture fo... | C20 |
1,748 | 5,037 | Testicular carcinoma in patients positive and at risk for human immunodeficiency virus.
Patients with the acquired immunodeficiency syndrome are at increased risk for certain malignancies.
Because acquired immunodeficiency syndrome and testicular cancer affect primarily young men, the potential complications that acq... | C20 |
1,749 | 5,280 | Angiotensin-converting-enzyme inhibitors and anaphylactoid reactions to high-flux membrane dialysis
In a retrospective study, 9 of 236 haemodialysis patients treated with high-flux polyacrylonitrile 'AN 69' membranes were found to have had anaphylactoid reactions.
Treatment with angiotensin-converting-enzyme (ACE) i... | C20 |
1,750 | 8,428 | Putative tyrosine kinases expressed in K-562 human leukemia cells.
Tyrosine phosphorylation is important in the transmission of growth and differentiation signals; known tyrosine kinases include several oncoproteins and growth factor receptors.
Interestingly, some differentiated cell types, such as erythrocytes and p... | C20 |
1,751 | 6,720 | Formoterol, a new inhaled beta-2 adrenergic agonist, has a longer blocking effect than albuterol on hyperventilation-induced bronchoconstriction.
The duration of effect of inhaled formoterol (24 micrograms) was compared with that of a placebo and that of inhaled albuterol (200 micrograms) in 12 adult asthmatic subject... | C20 |
1,752 | 7,277 | Suppressive effects of morphine pellet implants on in vivo parameters of immune function.
Chronic morphine treatment elicits a variety of immunosuppressive effects in mice.
Most of the work describing this immuno-suppressive activity of the opioid is based on in vitro assessments of the performance of certain compone... | C20 |
1,753 | 3,398 | Nasal lymphoma. A retrospective analysis of 60 cases.
Sixty cases of nasal lymphomas were reviewed.
There were 42 men and 18 women.
The median age was 49 years.
The histologic types were low grade in four cases, intermediate grade in 33, high grade in seven, and unclassifiable in 16.
Thirteen cases had features of... | C20 |
1,754 | 9,407 | AIDS following mother-to-child transmission of HIV-2.
Mother-to-child infection with HIV-2 is thought to be rare, and there have been few previous reports of transmission by this route.
Reports of morbidity associated with HIV-2 infection in children are also rare.
We describe eight children born to mothers who were... | C20 |
1,755 | 4,618 | The role of human immunodeficiency virus infection in pneumococcal bacteremia in San Francisco residents.
Human immunodeficiency virus (HIV) is an important risk factor for invasive pneumococcal disease, but information on clinical course and infecting serotypes is limited.
To help develop strategies to reduce the mo... | C20 |
1,756 | 2,762 | Effect of exercise on complement activity.
Complement measurements of C1, C1q, C2, C3, C4, C5; the anaphylatoxins, C3a, C4a, and C5a; and total hemolytic activity of the classical and alternative pathways were made in 26 experienced adult runners before and after shortterm aerobic exercise.
The baseline results were ... | C20 |
1,757 | 7,167 | Sexually transmitted diseases of the colon, rectum, and anus. The challenge of the nineties.
During the past two decades, an explosive growth in both the prevalence and types of sexually transmitted diseases has occurred.
Up to 55 percent of homosexual men with anorectal complaints have gonorrhea; 80 percent of the p... | C20 |
1,758 | 3,184 | Effects of GLQ223 on HIV replication in human monocyte/macrophages chronically infected in vitro with HIV.
GLQ223 is a formulated version of tricosanthin, a single-chain ribosome-inactivating protein that was shown in earlier studies to inhibit human immunodeficiency virus (HIV) replication in T-lymphoblastoid cells a... | C20 |
1,759 | 5,641 | Prevalence of human immunodeficiency virus seropositivity in pediatric emergency room patients undergoing phlebotomy.
Information on the prevalence of human immunodeficiency virus (HIV) infection among children and adolescents requiring medical care is sparse.
A small but significant risk of seroconversion occurs in ... | C20 |
1,760 | 3,603 | Membranous glomerulonephritis induced by 2-mercaptopropionylglycine (2-MPG).
Thirty-two patients suffering from cystinuria were treated with 2-mercaptopropionylglycine (2-MPG) for 0.5-10 years (average 6.3 years).
After 4-14 months of treatment at daily doses ranging from 500 to 2500 mg, three patients developed slig... | C20 |
1,761 | 5,341 | Coccidioidomycosis during human immunodeficiency virus infection. A review of 77 patients.
Through a retrospective review, we identified 77 previously unreported cases of coccidioidomycosis during HIV infection.
Patients were classified into 1 of 6 categories based on their primary clinical presentation: 20 had focal... | C20 |
1,762 | 7,040 | The impact of an AIDS symposium on attitudes of providers of pediatric health care.
Following reports of concern among health-care workers regarding the occupational risk of infection with the human immunodeficiency virus (HIV), a symposium was designed in 1987 to demonstrate to health-care providers at three hospital... | C20 |
1,763 | 7,041 | Attitudes of medical school faculty and students toward acquired immunodeficiency syndrome.
Attitudes of faculty and students will influence the success of educational programs to address acquired immunodeficiency syndrome (AIDS).
In 1988-89, 170 medical school faculty and 227 students completed needs assessment ques... | C20 |
1,764 | 2,790 | Endogenous opioids modulate the increase in ventilatory output and dyspnea during severe acute bronchoconstriction.
The aim of this study was to evaluate whether endogenous opioids are involved in the regulation of breathing pattern and respiratory drive during bronchoconstriction induced by methacholine (MCh).
We st... | C20 |
1,765 | 2,858 | Soluble interleukin-2 receptors in cerebrospinal fluid from individuals with various neurological disorders.
Soluble interleukin-2 (IL-2R) levels in the cerebrospinal fluid (CSF) were studied in infectious, inflammatory, degenerative, and neoplastic disorders to evaluate their usefulness as a marker for the presence o... | C20 |
1,766 | 7,155 | Evaluation and treatment of mental disorders in patients with AIDS.
Mental symptoms are common in patients with AIDS.
Optimal management involves the identification and treatment of underlying mental disorders rather than symptomatic treatment alone.
Organic mental disorders are very frequent in AIDS, particularly w... | C20 |
1,767 | 2,616 | Antidepressant pharmacotherapy of depression associated with multiple sclerosis.
In a double-blind clinical trial involving 28 patients with multiple sclerosis and major depressive disorder, 14 patients were randomly assigned to a 5-week trial of desipramine and individual psychotherapy and 14 to placebo plus psychoth... | C20 |
1,768 | 2,273 | HIV disease: a review for the family physician. Part I. Evaluation and conventional therapy.
Family physicians will be challenged with caring for increasing numbers of patients infected with human immunodeficiency virus.
After confirming the presence of the infection, the physician must follow a logical sequence of e... | C20 |
1,769 | 812 | Polyclonal B cell activation in lupus-prone mice precedes and predicts the development of autoimmune disease.
Polyclonal B cell activation is an early feature of autoimmune disease in humans and mice with systemic lupus erythematosus.
The contribution of polyclonal activation to the progression of autoimmunity is unc... | C20 |
1,770 | 3,187 | Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease.
Although macrophages are major targets for human immunodeficiency virus (HIV) infection in vivo, study of HIV-macrophage interactio... | C20 |
1,771 | 399 | Characteristics and correlates of asthma in a university clinic population.
To contribute more comprehensive information about the characteristics of asthma, this article analyzed patients served by the University of Alabama at Birmingham Comprehensive Asthma Program.
Their physicians rated one fifth of these patient... | C20 |
1,772 | 9,032 | Interleukin-2 immunotherapy in children.
Immunotherapy with interleukin (IL)-2 possesses great potential in the treatment of immune-mediated diseases and cancers.
However, only a few reports on a small number of children have appeared in the literature.
From March 1988 to March 1989, 11 children and adolescents were... | C20 |
1,773 | 7,078 | Serum soluble interleukin-2 receptor is associated with clinical and pathologic disease status in hairy cell leukemia
Hairy cell leukemia is a chronic lymphoproliferative disorder of B-cell lineage, whose malignant cells express the interleukin-2 (IL-2) receptor.
A soluble form of the IL-2 receptor is released by th... | C20 |
1,774 | 9,899 | A phase I study of recombinant human interferon-alpha 2a or human lymphoblastoid interferon-alpha n1 and concomitant zidovudine in patients with AIDS-related Kaposi's sarcoma.
To determine the safety, maximum tolerated dose, and preliminary efficacy of concomitant interferon-alpha and zidovudine therapy in AIDS-relate... | C20 |
1,775 | 6,800 | Increased MEPP frequency as an early sign of experimental immune-mediated motoneuron disease.
Intracellular recordings of miniature end-plate potentials were performed in extensor digitorum longus muscles from guinea pigs with experimental immune-mediated motoneuron destruction.
In the early stages of the disease, th... | C20 |
1,776 | 8,016 | Light microscopic diagnosis of human microsporidiosis and variable response to octreotide.
Microsporida are protozoan parasites that have recently been identified as a cause of human disease in immunocompromised patients.
Because of their small size, they have been recognized primarily by electron microscopy.
This h... | C20 |
1,777 | 8,371 | AIDS. Natural history and prognosis.
Infection with HIV results in a chronic, persistent infection that usually progresses slowly from an asymptomatic state to full-blown AIDS.
AIDS remains a lethal disease with no effective cure.
A great deal of information has been learned in the past decade, yet many questions re... | C20 |
1,778 | 7,633 | Low level atmospheric sulfur dioxide pollution and childhood asthma.
Quarterly analysis (1983-1987) of childhood asthma in Hong Kong from 13,620 hospitalization episodes in relation to levels of pollutants (SO2, NO2, NO, O3, TSP, and RSP) revealed a seasonal pattern of attack rates that correlates inversely with expos... | C20 |
1,779 | 2,764 | Bronchoconstriction induced by spirometric maneuvers in patients with bronchial asthma.
We analyzed forced expiration maneuver-induced bronchoconstriction in 14 asthmatic patients and in seven normal subjects by breaking down the forced expiration maneuver of spirometry (the FVC maneuver) into two phases: a slow, deep... | C20 |
1,780 | 3,673 | Monitoring glucocorticoid therapy: a pharmacokinetic approach.
Although glucocorticoid therapy is essential for the treatment of severe inflammatory disorders, there is no systematic approach to patient variables that may affect availability of a steroid dose.
After the development of a data base of pharmacokinetic p... | C20 |
1,781 | 415 | Effect of PAF-acether inhalation on nonspecific bronchial reactivity and adrenergic response in normal and asthmatic subjects.
Bronchial hyperreactivity, although recognized as a hallmark of asthma, is not totally understood.
Mast cell-derived mediators, including histamine, have been shown to cause immediate broncho... | C20 |
1,782 | 7,558 | Lymphoma presenting as a periorbital tumor.
Lymphoma is a common tumor of the periorbital region.
Facial radiographs may show a soft tissue mass.
Radiologic differential diagnosis of orbital masses is difficult.
Computed tomographic scanning with intravenous contrast medium is useful in diagnosing and staging neopl... | C20 |
1,783 | 7,093 | Cell membrane expression and functional role of the p75 subunit of interleukin-2 receptor in lymphoproliferative disease of granular lymphocytes.
The cell membrane expression and functional role of the interleukin-2 receptor (IL-2R) was analyzed in nine patients with lymphoproliferative disease of granular lymphocytes... | C20 |
1,784 | 5,727 | Myelin autoreactivity in multiple sclerosis: recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple-sclerosis patients and healthy donors.
A panel of 20 human myelin basic protein (hMBP)-specific T-lymphocyte lines was generated from the peripheral blood of eight multiple s... | C20 |
1,785 | 9,283 | Severe anemia is an important negative predictor for survival with disseminated Mycobacterium avium-intracellulare in acquired immunodeficiency syndrome [published erratum appears in Am Rev Respir Dis 1991 Feb;143(2):451]
Disseminated Mycobacterium avium-intracellulare (MAI) in patients with the acquired immunodeficie... | C20 |
1,786 | 845 | Photochemotherapy improves chronic cutaneous graft-versus-host disease.
We have used oral psoralen photochemotherapy (PUVA) to treat four patients with chronic graft-versus-host disease of the skin, oral mucosa, and liver, who had responded only partially to long-term immunosuppressive therapy (prednisolone, cyclospor... | C20 |
1,787 | 2,078 | Cytomegalovirus-induced osteomyelitis in a patient with the acquired immunodeficiency syndrome.
A 43-year-old man with AIDS had a periodontal abscess, no fever, and normal findings on funduscopic examination.
Three months later, the abscess area was debrided, and histologic examination of the tissue revealed osteomye... | C20 |
1,788 | 3,419 | Immune deficiency in family members of patients with Hodgkin's disease.
Indirect data supporting a preexisting immunologic impairment in patients with Hodgkin's disease (HD) have been presented in recent years.
These immunologic defects are supposed to be related to genetic and/or environmental factors.
In this stud... | C20 |
1,789 | 4,647 | Analysis of lymphocytes, monocytes, and neutrophils from human immunodeficiency virus (HIV)-infected persons for HIV DNA.
The human immunodeficiency virus (HIV) infects and depletes or alters the function of cells involved in immune responsiveness.
While both T helper lymphocytes and monocyte/macrophages can be infec... | C20 |
1,790 | 7,014 | Association of labial salivary gland histopathology with clinical and serologic features of connective tissue diseases.
Focal sialadenitis is now widely accepted as an objective criterion for the oral component of Sjogren's syndrome (xerostomia).
We investigated the association between labial salivary gland histopath... | C20 |
1,791 | 4,293 | Thyroiditis as the presenting manifestation of disseminated extrapulmonary Pneumocystis carinii infection.
A 38-yr-old male with acquired immunodeficiency syndrome developed neck pain in association with mild hyperthyroidism and a diffusely enlarged thyroid gland.
Radioactive iodine scanning was consistent with thyro... | C20 |
1,792 | 6,168 | HIV disease: a review for the family physician. Part II. Secondary infections, malignancy and experimental therapy.
The first part of this two-part article included recommendations for the initial evaluation of patients suspected of having HIV infection, the Centers for Disease Control's classification scheme for HIV ... | C20 |
1,793 | 7,094 | Association of bcl-1 rearrangements with lymphocytic lymphoma of intermediate differentiation.
Previous studies using classical cytogenetics have demonstrated the presence of the t(11;14) (q13;q32) chromosomal translocation in some cases of lymphocytic lymphoma of intermediate differentiation (IDL), a distinct type of... | C20 |
1,794 | 6,509 | Epidemiology of reported cases of AIDS in lesbians, United States 1980-89.
National surveillance data for reported cases of acquired immunodeficiency syndrome (AIDS) were used to assess demographic characteristics and behavioral risk factors in lesbians.
From June 1, 1980 through September 30, 1989, 79 women with AID... | C20 |
1,795 | 8,518 | Primary lymphoma of prostate: transrectal ultrasonic appearance.
In the case presented, primary lymphoma of the prostate was diagnosed by ultrasonically guided transrectal biopsy.
Primary lymphoma of the prostate should be included in the differential diagnosis of a hypoechoic lesion found on ultrasonic evaluation of... | C20 |
1,796 | 7,022 | Rescue of interleukin-1 activity by leucovorin following inhibition by methotrexate in a murine in vitro system.
We have recently shown that methotrexate (MTX) inhibits interleukin-1 (IL-1) activity in vitro.
This effect may play an important role in the rapid antiinflammatory action of MTX in rheumatoid arthritis.
... | C20 |
1,797 | 9,138 | Cardiovascular anomalies associated with prenatal exposure to theophylline.
Theophylline has been shown to be a potent cardiovascular teratogen in animals, but there has been no evidence linking theophylline with congenital anomalies in infants.
The cardiovascular anomalies in our three patients were aortic anomalies... | C20 |
1,798 | 9,923 | The spondyloarthropathies in Zimbabwe: a clinical and immunogenetic profile.
Spondyloarthropathies are rare in Africa and there is little data regarding HLA association.
We prospectively studied 19 patients with spondyloarthropathy, recording clinical details and performing tissue typing (ABC loci).
There were 9 pat... | C20 |
1,799 | 4,812 | An early phase II study of CPT-11: a new derivative of camptothecin, for the treatment of leukemia and lymphoma.
An early phase II study of a new camptothecin analog and an inhibitor of topoisomerase I, CPT-11, was conducted in 62 patients with refractory leukemia and lymphoma by four different treatment schedules in ... | C20 |
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