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2,000 | 6,771 | Effect of human immunodeficiency virus (HIV) infection on the course of syphilis and on the response to treatment.
PURPOSE: To evaluate evidence that concurrent infection with human immunodeficiency virus (HIV) alters both the natural history of syphilis (by increasing the frequency of early neurosyphilis) and the res... | C20 |
2,001 | 8,373 | Human immunodeficiency virus education and screening of prenatal patients.
Prenatal HIV education and testing requires access to many resources and is demanding of time and personnel.
Properly trained sympathetic on-site counselors are essential.
Such personnel may combine this role with other tasks but should have ... | C20 |
2,002 | 2,869 | In vitro cultivation of Cryptosporidium parvum and screening for anticryptosporidial drugs.
Sporozoites of Cryptosporidium parvum which were excysted in vitro from oocysts isolated from calves or patients with acquired immune deficiency syndrome underwent development in monolayers of the mouse fibroblast cell line L92... | C20 |
2,003 | 3,188 | The effect of interleukin 4 (BSF-1) on infection of peripheral blood monocyte-derived macrophages with HIV-1.
The effects of various cytokines were examined in an in vitro model of human immunodeficiency virus type 1 (HIV-1) infection of human peripheral blood monocyte-derived macrophages (MDM).
Monocytes were obtain... | C20 |
2,004 | 9,404 | Response of mononuclear cells from HIV-infected patients to B-cell mitogens: correlation with immunological and clinical features of disease progression.
Proliferation of mononuclear cells from HIV-seropositive patients to B-cell mitogens was studied in the absence and presence of mixed lymphocyte culture supernatants... | C20 |
2,005 | 5,380 | A controlled trial of early adjunctive treatment with corticosteroids for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. California Collaborative Treatment Group.
BACKGROUND.
Pneumocystis carinii pneumonia remains a common cause of serious morbidity and mortality in patients with the acquir... | C20 |
2,006 | 387 | Mucoid impaction of upper lobe bronchi in the absence of proximal bronchiectasis.
Mucoid impaction is a complication of asthma and is frequently recurrent in patients with allergic bronchopulmonary aspergillosis (ABPA).
This report describes a patient with asthma and recurrent bilateral well-circumscribed densities o... | C20 |
2,007 | 5,952 | Successful strategy for prevention of cytomegalovirus interstitial pneumonia after human leukocyte antigen-identical bone marrow transplantation.
Cytomegalovirus (CMV) interstitial pneumonia is a frequent and often fatal complication of allogeneic bone marrow transplantation.
Because therapy for CMV pneumonia was, un... | C20 |
2,008 | 3,295 | Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens
A randomized trial of 12.0 Gy versus 15.75 Gy of total body irradiation (TBI) was performed in patients with acute myeloid leukemia undergoing allogeneic marrow transplantation ... | C20 |
2,009 | 9,753 | Metabolic studies of radioiodinated serum amyloid P component in normal subjects and patients with systemic amyloidosis.
125I-Serum amyloid P component (SAP), injected intravenously into 10 normal subjects, remained predominantly intravascular with mean (SD) T1/2 (half time) in plasma of 24.5 (5.9) h.
The fractional ... | C20 |
2,010 | 6,318 | Immune complexes in pediatric human immunodeficiency virus infection.
Circulating immune complexes (CIC) were analyzed in a cohort of 30 children infected with the human immunodeficiency virus.
Elevated CIC were detected by the C1q assay in 70% (21/30) of all patients and by the Raji cell assay in 93% (28/30) of all ... | C20 |
2,011 | 6,710 | IgG1-mediated acute pulmonary hypersensitivity response in the guinea pig. Involvement of specific lipid mediators.
We determined the pulmonary obstructive response to aerosolized antigen challenge, and its sensitivity to antagonists of specific lipid mediators, in IgG, passively sensitized (IgG1-PS) guinea pigs.
Ant... | C20 |
2,012 | 5,933 | Tropical neuromyelopathies and retroviruses: a review.
Debilitating disorders of the nervous system have a relatively high prevalence in the tropics, a geographic region that is often deficient in specialists in the fields of neurology and epidemiology.
During World War II, attention was called to a possible nutritio... | C20 |
2,013 | 9,933 | Diagnostic criteria for neuropsychiatric systemic lupus erythematosus: the results of a consensus meeting. The Ad Hoc Neuropsychiatric Lupus Workshop Group.
Definitions and classifications proposed for the neuropsychiatric complications of systemic lupus erythematosus (NP-SLE) indicate a wide range of approaches taken... | C20 |
2,014 | 8,736 | Enhanced percutaneous absorption of a novel topical cyclosporin A formulation and assessment of its immunosuppressive activity.
No clinically successful topical cyclosporin A (CyA) formulation has been produced, mainly due to the apparent lack of drug penetration.
This study has produced the first in vitro kinetic da... | C20 |
2,015 | 8,377 | Human immunodeficiency virus infection in pregnancy.
Among an estimated 1 million to 1.5 million Americans infected with HIV, about 10 per cent are women.
Moreover, almost 30 per cent of HIV infection among women is acquired through heterosexual activity.
Therefore, the average obstetrician/gynecologist is not shelt... | C20 |
2,016 | 8,321 | Regular inhaled beta-agonist treatment in bronchial asthma
89 subjects with stable asthma took part in a double-blind, placebo-controlled, randomized, crossover study of the effects of regular versus on-demand inhaled bronchodilator therapy.
The subjects inhaled fenoterol or placebo by a dry powder delivery system f... | C20 |
2,017 | 9,289 | Genetics of asthma and hay fever in Australian twins.
The occurrence of self-reported asthma/wheezing and hay fever among 3,808 pairs of twins from the Australian National Health and Medical Research Council Twin Registry was examined for evidence of genetic transmission by path analytic methods.
The cumulative preva... | C20 |
2,018 | 7,042 | Medical and nursing students' attitudes about AIDS issues.
A 12-item questionnaire was administered in late 1987-early 1988 to 445 medical students, 133 medical school applicants, and 111 nursing students to assess any differences in their attitudes toward medicine-related AIDS issues.
These groups were also given a ... | C20 |
2,019 | 6,685 | Prehospital administration of inhaled metaproterenol.
STUDY OBJECTIVES: We conducted a study of the prehospital use of inhaled metaproterenol.
DESIGN, SETTING, TYPE OF PARTICIPANTS, AND INTERVENTIONS: Advanced life support (ALS) providers were trained with a standardized curriculum to identify patients likely to bene... | C20 |
2,020 | 9,419 | A semiquantitative microassay for measurement of relative number of blood mononuclear cells infected with human immunodeficiency virus.
A simple semiquantitative microassay was developed for the measurement of relative number of infected peripheral blood mononuclear cells (PBMC) from individuals infected with human im... | C20 |
2,021 | 329 | The surgery of juvenile chronic arthritis. An overview.
Surgery now has a well-established place in the management of childhood arthritis.
However, satisfactory results can only be achieved by a team of medical experts composed of a pediatric rheumatologist, an orthopedic surgeon, an anesthetist, a physiotherapist, a... | C20 |
2,022 | 7,637 | Evaluation of ketotifen in corticosteroid-dependent idiopathic anaphylaxis.
To study the possible efficacy of ketotifen (K) in the treatment of idiopathic anaphylaxis (IA), K was administered in an open-label trial to six patients with IA who required corticosteroids at doses below which their disease could not be con... | C20 |
2,023 | 2,860 | Multiple sclerosis is prevalent in the Zoroastrians (Parsis) of India.
Using Schumacher's classification, we determined the prevalence rate of clinically definite multiple sclerosis (MS) in the distinct but tiny Zoroastrian (largely Parsi) community in the adjacent cities of Bombay (latitude, 18.55 degrees) and Poona ... | C20 |
2,024 | 3,428 | Non-Hodgkin's lymphoma in the elderly. I. Pathologic features at presentation.
The pathologic findings of 118 patients aged 70 years or older with non-Hodgkin's lymphoma (NHL) are reported.
These patients formed 27.2% of 433 consecutive cases of NHL seen in a single institution over a 5-year period.
Thirty-one of 43... | C20 |
2,025 | 9,406 | Rapid and specific diagnosis of HIV-1 and HIV-2 infections: an evaluation of testing strategies.
To identify cost-effective testing strategies for HIV-1 and HIV-2 infections, we evaluated different combinations of tests on serum specimens from 1134 consecutive patients attending tuberculosis treatment centers in Abidj... | C20 |
2,026 | 944 | The relationships among shrimp-specific IgG subclass antibodies and immediate adverse reactions to shrimp challenge.
High levels of shrimp-specific IgE, in association with a positive prick test, are not always predictive of a positive, immediate response to double-blind, placebo-controlled, food challenge (DBPCFC) wi... | C20 |
2,027 | 6,056 | Cataract extraction in uveitis patients.
Cataracts are known to develop at an accelerated rate in many forms of uveitis.
Until recently, cataract surgery in such eyes was regarded as a hazardous procedure that yielded unpredictable and often discouraging results.
Recent evidence from a number of reports suggests tha... | C20 |
2,028 | 6,551 | Human T cell lymphotropic virus infection in Guaymi Indians from Panama.
Preliminary studies found that 9% of Guaymi Indians from Bocas del Toro province have antibody to human T cell lymphotropic virus (HTLV-I/II).
The present study enrolled 317 (21% of the population) Guaymi Indians from Changuinola, the capital of... | C20 |
2,029 | 5,914 | Tuberculous psoas muscle abscess following chemoprophylaxis with isoniazid in a patient with human immunodeficiency virus infection.
A 34-year-old man with human immunodeficiency virus infection and disseminated Mycobacterium avium and Mycobacterium intracellulare infection developed a right psoas muscle abscess due t... | C20 |
2,030 | 5,605 | Oral histoplasmosis as a presenting disease in acquired immunodeficiency syndrome [published erratum appears in Oral Surg Oral Med Oral Pathol 1991 Jan;71(1):76]
A 43-year-old homosexual man visited his dentist with painful, nodular, ulcerated lesions on the soft palate, right buccal mucosa, and right posterior maxill... | C20 |
2,031 | 8,794 | Primary central nervous system lymphoma in a pediatric patient with acquired immune deficiency syndrome. Treatment with radiation therapy.
Primary central nervous system (CNS) lymphoma, an otherwise rare pediatric tumor, has been reported with increasing frequency in children with acquired immune deficiency syndrome (... | C20 |
2,032 | 9,019 | Annual summary of vital statistics--1989.
US infant mortality continued to decline slowly and the provisional 1989 rate, 9.7 per 1000 live births, was the lowest ever recorded.
Final 1988 data showed no change in cause of death distribution or in the wide discrepancy between white and black infant mortality.
State r... | C20 |
2,033 | 4,553 | Synergistic effect of murine cytomegalovirus on the induction of acute graft-vs-host disease involving MHC class I differences only. Analysis of in vitro T cell function.
The development of acute graft-vs-host disease (GVHD) is a common outcome after the injection of fully MHC disparate parental T cells into unirradia... | C20 |
2,034 | 4,310 | Value of monoclonal anti-myeloperoxidase (MPO7) for diagnosing acute leukaemia.
The expression of myeloperoxidase (MPO) was studied in 100 cases of acute leukaemia (83 with acute myeloid leukaemia (AML) and 17 acute lymphoblastic leukaemia (ALL) by both a conventional cytochemical method and the immunocytochemical ant... | C20 |
2,035 | 2,802 | Sarcoidosis complicated by HIV infection: three case reports and a review of the literature.
We report three cases of sarcoidosis complicated by human immunodeficiency virus (HIV) infection and review four other isolated case reports in the literature.
There is clinical overlap of both diseases, including symptoms, p... | C20 |
2,036 | 2,520 | Immunoproliferative small intestinal disease: portrait of a potentially preventable cancer from the Third World.
PURPOSE: To review the recent progress in the understanding of clinical and laboratory characterization as well as management of immunoproliferative small intestinal disease (IPSID).
DATA IDENTIFICATION: A... | C20 |
2,037 | 6,172 | Tartrazine sensitivity.
Tartrazine (FD & C Yellow No.
5) is an approved azo dye present in many drugs and food products.
During the 1970s, many cases of tartrazine sensitivity were reported.
This led to new regulations that required the listing of azo dyes on package inserts of drugs and on packages of food product... | C20 |
2,038 | 4,442 | Elevated serum interleukin-6 associated with a failure in B cell differentiation in common variable immunodeficiency.
Interleukin-6 (IL-6/B cell stimulatory factor 2) has been found to drive activated human B-lymphocytes through the final stages of differentiation to become immunoglobulin-producing cells.
Most patien... | C20 |
2,039 | 7,020 | Nontropical pyomyositis as a cause of subacute, multifocal myalgia in the acquired immunodeficiency syndrome.
We report a case of nontropical pyomyositis in a patient with acquired immunodeficiency syndrome and disseminated Mycobacterium avium infection, in which severe myalgia was the presenting symptom over several ... | C20 |
2,040 | 5,885 | Pharmacotherapy of asthma and allergic rhinitis.
It has become easier to treat and control the symptoms of asthma, while the treatment of allergies remains directed toward the prevention and blockade of histamine-induced symptoms.
This article details treatment options, including beta-2 selective sympathomimetic agon... | C20 |
2,041 | 8,320 | The interrelationship between human immunodeficiency virus infection and other sexually transmitted diseases.
The epidemiology of HIV infection in the United States is changing, with a dramatic reduction in the incidence of new HIV infection in homosexual men over the past decade because of altered sexual practices.
... | C20 |
2,042 | 4,778 | Headaches and multiple sclerosis: a clinical study and review of the literature.
Whether multiple sclerosis (MS) can cause headaches is controversial.
To clarify the association between headaches and MS we prospectively analyzed 104 consecutive MS patients using detailed headache evaluations.
Fifty-four patients (52... | C20 |
2,043 | 6,523 | Association of hepatitis B surface antigen and core antibody with acquisition and manifestations of human immunodeficiency virus type 1 (HIV-1) infection.
We examined the associations between seropositivity for hepatitis B virus (HBV) with the presence or development of antibodies to human immunodeficiency virus (HIV-... | C20 |
2,044 | 9,410 | High HIV risk-taking among young gay men.
Previous research has shown younger age to be correlated with greater HIV sexual risk-taking among gay men.
The purpose of this study was to identify variables associated with HIV risk-taking among younger gay men.
Ninety-nine gay men aged 18-25 in three medium-sized West Co... | C20 |
2,045 | 92 | A retrospective analysis of therapy for acute graft-versus-host disease: initial treatment.
We have reviewed results of therapy in 740 patients with grades II-IV acute graft-versus-host disease (GVHD) after allogeneic marrow transplantation.
At the beginning of therapy, 597 patients (81%) had rash, 369 (50%) had live... | C20 |
2,046 | 7,635 | Effect of procaterol on arterial blood gas in asthmatic children.
We determined changes in arterial blood gas after the inhalation of procaterol, a highly beta 2-selective and long-acting adrenergic agonist, in 11 asthmatic children.
Seven of the patients, with a maximum fall of 14 mmHg (63.6%), showed a decrease in ... | C20 |
2,047 | 6,815 | Characterization of the dermal infiltrate in human immunodeficiency virus-infected patients with psoriasis.
We investigated the dermal inflammatory cell infiltrates of psoriatic lesions from nine human immunodeficiency virus-infected patients and nine age-, sex-, and site-matched control specimens.
The study was retr... | C20 |
2,048 | 7,092 | Expression of P-glycoprotein in adult T-cell leukemia cells.
We have examined the expression of P-glycoprotein (P-gp) in adult T-cell leukemia (ATL) samples from 25 patients.
Based on immunoblotting with a monoclonal antibody against P-gp, C219, 8 of 20 ATL patients were P-gp positive at the initial presentation.
Al... | C20 |
2,049 | 7,626 | Lymphangiomyomatosis--newer concepts in pathogenesis and management--case reports.
Lymphangiomyomatosis was first reported more than forty years ago.
Although its incidence is rare, its occurrence is being increasingly recognized and has been the subject of a growing number of cases reports in recent years.
This stu... | C20 |
2,050 | 555 | Studies on autoimmunity for initiation of beta-cell destruction. VI. Macrophages essential for development of beta-cell-specific cytotoxic effectors and insulitis in NOD mice.
NOD mice were treated with silica (which is selectively toxic to macrophages) from 4 or 20.5 wk of age.
Syngeneic neonatal pancreases were tra... | C20 |
2,051 | 6,083 | Surgical experience with cerebral amyloid angiopathy.
Cerebral amyloid angiopathy can present as lobar intracerebral hemorrhage in an elderly person, presumably due to increased fragility of the vessels affected by amyloid deposition.
For this reason, patients presenting with intracerebral hemorrhage and suspected of... | C20 |
2,052 | 5,938 | Therapeutic approaches to neoplasms in AIDS.
The multifactorial etiology of Kaposi's sarcoma (KS), which is seen primarily in men, includes genetic predisposition and immunosuppression.
Recently, the KS seen in association with human immunodeficiency virus (HIV) infection has been shown to be mediated by the producti... | C20 |
2,053 | 7,787 | Angiocentric immunoproliferative lesion/T-cell non-Hodgkin's lymphoma and the acquired immune deficiency syndrome: a case report and review of the literature.
The lesions known as lymphocytic vasculitis, polymorphic reticulosis (midline malignant reticulosis, lethal midline granuloma), lymphomatoid granulomatosis, and... | C20 |
2,054 | 6,491 | Modeling the impact of breast-feeding by HIV-infected women on child survival [published erratum appears in Am J Public Health 1991 May;81(5):658-9]
This study models the survival outcomes of children born to HIV-infected (human immunodeficiency virus) women who are breast-fed, bottle-fed, and wet-nursed.
It is estim... | C20 |
2,055 | 3,408 | Treatment of the acquired immune deficiency syndrome-related Kaposi's sarcoma with bleomycin as a single agent.
A nonrandomized trial was conducted to assess the efficiency and toxicity of bleomycin as a single agent in treatment of non-life-threatening AIDS-related Kaposi's sarcoma (KS).
Sixty patients were enrolled... | C20 |
2,056 | 3,765 | Dialysis-induced respiratory acidosis.
The inability to increase alveolar ventilation can lead to CO2 retention and acute respiratory acidosis in patients with ventilatory limitation.
In this case, a young woman receiving maximum ventilatory support was unable to excrete excess CO2, associated with increasing dianeal... | C20 |
2,057 | 4,089 | Transfusion risks.
Hepatitis remains the most serious transfusion risk, in terms of incidence and severity.
Transfusion-associated AIDS, hemolytic reactions, TRALI, and anaphylaxis are severe problems that occur relatively rarely, while febrile reactions and mild allergic reactions are common but not serious.
The ke... | C20 |
2,058 | 5,954 | Cytomegalovirus infection in children with AIDS.
Data for 38 children perinatally exposed to human immunodeficiency virus (HIV) were evaluated to determine the impact of cytomegalovirus (CMV) infection on the course of perinatally acquired HIV infection.
Thirteen children belonged to the P0 (indeterminate) group, one... | C20 |
2,059 | 2,757 | Basophil histamine release and airway response to mite allergen in atopic dermatitis.
Twelve patients with atopic dermatitis (AD) were subjected to in vitro histamine release from peripheral blood leukocytes (basophils) and in vivo bronchial inhalation challenge using house dust mite (Dermatophagoides farinae) allerge... | C17 |
2,060 | 5,850 | Correcting a stairstep deformity secondary to lower abdominal scars by the use of a decorticated hypogastric flap.
The author describes a decorticated hypogastric flap used in the correction and prevention of retracted scars and suprapubic stairsteps.
These deformities are common after cesarean sections and in patien... | C17 |
2,061 | 8,589 | Anisocoria in the pigmentary dispersion syndrome
We studied four patients with anisocoria and the pigmentary dispersion syndrome.
In all patients, the larger pupil was on the side of the greater iris transillumination.
The amount of anisocoria was between 0.5 and 1.5 mm and was the same in both the light and dark.
... | C17 |
2,062 | 5,540 | The significance of moderate and severe inflammation on class I Papanicolaou smear
The significance of a cytologic diagnosis of moderate and severe inflammation with a normal (class I) Papanicolaou smear has not been addressed.
A retrospective review of 596 consecutive cervical smears performed over 13 months reveal... | C17 |
2,063 | 347 | Olive oil as a cause of contact allergy in patients with venous eczema, and occupationally.
From 1985 to 1989, 13 cases of contact allergy to olive oil have been identified in the Departments of Dermatology of Kristianstad and Ostersund Hospitals.
Known components of olive oil could not be proved to be the cause of t... | C17 |
2,064 | 4,325 | A comparative histopathologic study of photodistributed and nonphotodistributed lichenoid drug eruptions.
This study compares the histopathologic characteristics of photodistributed and nonphotodistributed lichenoid drug eruptions in 13 patients.
Both types have been said to be, in an unknown proportion, different fr... | C17 |
2,065 | 460 | Comparison of quantitative sensory-threshold measures for their association with foot ulceration in diabetic patients.
We compared the accuracy of cutaneous pressure perception-threshold measurements with that of other sensory-threshold measurements for detecting diabetic foot ulcer patients.
Three hundred fourteen n... | C17 |
2,066 | 5,578 | Serum and aqueous humor sialic acid levels in Behcet's disease.
Serum and aqueous humor sialic acid (SA) levels were determined in 27 patients with Behcet's disease (Bd).
Serum SA levels were elevated significantly during the active episode (mean, 113.4 +/- 4.12 mg/dl) and in the remission stages (mean, 85.4 +/- 4.79... | C17 |
2,067 | 5,595 | Comprehensive dental care and general anesthetic management of hereditary epidermolysis bullosa. A review of fourteen cases.
Dental management of persons with epidermolysis bullosa remains challenging because of the severe hard and soft tissue manifestations of these diseases.
This study reviews the dental treatment ... | C17 |
2,068 | 9,036 | Response to diet and cholestyramine in a patient with sitosterolemia.
In this report, an 11-year-old boy with diffuse tendinous and tuberous xanthomatosis and a plasma sterol concentration of 555 mg/dL, consisting primarily of cholesterol, is described.
Three months after changing from an unrestricted diet to a chole... | C17 |
2,069 | 5,140 | Deep vein obstruction and leg swelling caused by femoral ganglion.
We present a case of a rare ganglion cyst originating from the hip joint and compressing the common femoral vein producing signs and symptoms that mimicked a deep vein thrombosis.
Excision of the mass promptly restored normal venous return.
This cond... | C17 |
2,070 | 6,809 | Spinal cord compression with paraplegia in xanthomatosis due to normocholesterolemic sitosterolemia.
A 48-year-old woman with a 30-year history of tendinous xanthomatosis developed paraplegia.
The magnetic resonance image revealed extramedullary tumors.
The analysis of her sera and tumors revealed increased amount o... | C17 |
2,071 | 9,737 | Total hip arthroplasty with cement. A long-term radiographic analysis in patients who are older than fifty and younger than fifty years.
The long-term performance of a total of 712 Charnley and STH prostheses was evaluated as a function of the patient's age (older than fifty years or younger than fifty years) and of t... | C17 |
2,072 | 3,267 | Linear scleroderma associated with ptosis and motility disorders.
A case is reported in which an 11-year-old girl developed progressive ptosis and a subsequent motility disorder of the right eye.
The diagnosis linear scleroderma en coup de sabre was established.
Atrophy of the upper levator palpebral and superior re... | C17 |
2,073 | 4,323 | Treatment of idiopathic guttate hypomelanosis with liquid nitrogen: light and electron microscopic studies.
Idiopathic guttate hypomelanosis is a common skin disorder of unknown cause.
Our studies have shown that significantly fewer dopa-positive melanocytes are in the white macules of idiopathic guttate hypomelanosi... | C17 |
2,074 | 9,786 | Clinical association of autoantibodies to fibrillarin with diffuse scleroderma and disseminated telangiectasia.
Circulating autoantibodies against a variety of nuclear and nucleolar antigens are characteristic serologic findings in systemic scleroderma.
Some of these antibodies correlate with clinical subsets of the ... | C17 |
2,075 | 8,732 | Immediate contact reactions to chemicals in the fragrance mix and a study of the quenching action of eugenol.
In this study, the nature of non-immune immediate contact reactions (NIICR) produced by cinnamic aldehyde, benzoic acid and sorbic acid were investigated, with particular interest in the 'quenching' ability of... | C17 |
2,076 | 3,767 | Labetalol and MRI as initial medical and diagnostic modalities in a marfanoid patient with expanding ascending aortic aneurysm.
Marfan syndrome is a hereditable disorder of connective tissue that causes several distinct cardiovascular abnormalities, including aortic regurgitation, dissection, and aneurysm.
These card... | C17 |
2,077 | 8,636 | Treatment of chronic liver disease caused by 3 beta-hydroxy-delta 5-C27-steroid dehydrogenase deficiency with chenodeoxycholic acid.
Deficiency of 3 beta-hydroxy-delta 5-C27-steroid dehydrogenase, the second enzyme in the sequence that catalyses the synthesis of bile acids from cholesterol, leads to chronic liver dise... | C17 |
2,078 | 7,932 | 11 beta-hydroxyandrostenedione: a marker of adrenal function in hirsutism.
To assess the role of the adrenal glands in the development of hirsutism, levels of 11 beta-hydroxyandrostenedione (11 beta-OHA), 17 alpha-hydroxyprogesterone (17-OHP), dehydroepiandrosterone sulphate (DHEAS), androstenedione (delta 4A), and fr... | C17 |
2,079 | 878 | Itraconazole in the treatment of tinea capitis.
Fifty patients with tinea capitis were treated with itraconazole, 25 to 100 mg/day, for 20 to 73 days in six countries.
Forty-seven patients (94%) responded clinically (healed or markedly improved) to therapy, of which 38 patients (76%) completely healed and 9 patients ... | C17 |
2,080 | 864 | Scleroderma and L-tryptophan: a possible explanation of the eosinophilia-myalgia syndrome.
Scleroderma developed in six women who were taking L-tryptophan.
Fasciitis and morphea were most common, but one patient had pleural effusion, hypertension, and signs of cardiac and kidney failure.
In five patients the biopsy ... | C17 |
2,081 | 860 | Cutaneous lesions of disseminated histoplasmosis in human immunodeficiency virus-infected patients.
Disseminated histoplasmosis is being diagnosed more frequently in persons infected with the human immunodeficiency virus and is often the initial manifestation of the acquired immunodeficiency syndrome (AIDS).
Disease-... | C17 |
2,082 | 8,730 | Induction of ornithine decarboxylase following sellotape stripping in normal and psoriatic skin.
Ornithine decarboxylase (ODC) was measured in the epidermis of healthy volunteers and the uninvolved skin of psoriatic patients at various times after sellotape stripping.
Basal levels were less than 1 pmol/min/mg protein... | C17 |
2,083 | 2,894 | Abnormal essential fatty acid metabolism in Darier's disease.
Fatty acid levels in plasma and erythrocyte cell membranes were determined in 13 Danish patients with Darier's disease and 21 Danish controls.
Concentrations of the main dietary essential fatty acids, linoleic acid (18:2n-6) and alpha-linolenic acid (18:3n... | C17 |
2,084 | 2,262 | Tryptophan-induced eosinophilia-myalgia syndrome
Eight patients who became ill while taking tryptophan had myalgia, fatigue, rash, fever, edema, alopecia, arthralgias, diminished joint motion, skin tightening, muscle cramping, and distal paresthesias.
Three had shortness of breath, and one had pulmonary hypertension... | C17 |
2,085 | 2,741 | The effect of local temperature versus sympathetic tone on digital perfusion in Raynaud's phenomenon.
Matched groups of 7 to 8 patients with primary Raynaud's phenomenon, systemic sclerosis, and undifferentiated connective tissue disease and cold-tolerant normal control subjects were studied by simultaneous digital st... | C17 |
2,086 | 4,651 | Treatment of condyloma acuminatum with three different interferon-alpha preparations administered parenterally: a double-blind, placebo-controlled trial.
One hundred seventy-eight patients were enrolled in a placebo-controlled trial to evaluate three interferon-alpha preparations administered parenterally for the trea... | C17 |
2,087 | 3,649 | Comparison of patellar resurfacing versus nonresurfacing in bilateral total knee arthroplasty.
Twenty-five patients who received bilateral total knee prostheses were studied to evaluate the advantages and disadvantages of patellar resurfacing.
Only patients with advanced patellofemoral disease were included in the st... | C17 |
2,088 | 4,357 | Linear porokeratosis: successful treatment with diamond fraise dermabrasion.
A patient with linear porokeratosis was successfully treated with diamond fraise dermabrasion.
Follow-up evaluation revealed an excellent cosmetic result with adequate repigmentation, no scarring, and no recurrence of lesions.
Long-term fol... | C17 |
2,089 | 4,583 | Immunologic mechanisms in psoriasis.
The demonstration of activated T lymphocytes, HLA-DR+, I-CAM1+, gamma IP-10+ keratinocytes, and increased levels of lymphokines in active plaques suggests that immunologic mechanisms may play a role in the pathogenesis of psoriasis.
Epidermal hyperplasia and inflammation in psoria... | C17 |
2,090 | 3,086 | Human immunodeficiency virus-associated psoriasis, psoriatic arthritis, and Reiter's syndrome: a disease continuum?
The presence of peripheral arthritis and HLA-A, B, C, DR, and DQ antigens was evaluated prospectively in 18 Caucasian men with human immunodeficiency virus-associated psoriasis.
An asymmetric polyarthri... | C17 |
2,091 | 3,595 | IgA nephritis in Behcet's disease: case report and review of the literature.
We describe a 13-year-old girl with the incomplete type of Behcet's disease who had recurrent oral and genital ulcers, folliculitis, proteinuria and hematuria.
Renal biopsy specimens revealed diffuse proliferative glomerulonephritis with str... | C17 |
2,092 | 68 | Skin manifestations in congenital deficiency of leucocyte-adherence glycoproteins (CDLG).
In congenital deficiency of leucocyte-adherence glycoproteins (CDLG) there is an immunodeficiency with impaired leucocyte function and cutaneous and extracutaneous infections occur.
In more than 30% of cases the condition has a ... | C17 |
2,093 | 7,178 | Uroporphyrinogen decarboxylase: a splice site mutation causes the deletion of exon 6 in multiple families with porphyria cutanea tarda.
Uroporphyrinogen decarboxylase (URO-D) is a cytosolic heme-biosynthetic enzyme that converts uroporphyrinogen to coproporphyrinogen.
Defects at the uroporphyrinogen decarboxylase loc... | C17 |
2,094 | 2,901 | Autoantibodies from patients with localized and generalized bullous pemphigoid immunoprecipitate the same 230-kd keratinocyte antigen.
Two patients demonstrating the typical clinical, histologic, and immunopathologic features of nonscarring localized bullous pemphigoid are described.
These patients possess circulatin... | C17 |
2,095 | 879 | Itraconazole in the management of chronic dermatophytosis.
Fifty-five patients with griseofulvin-unresponsive dermatophytosis caused by Trichophyton rubrum were treated with itraconazole.
They had either tinea corporis or "dry type" infections of the palms, soles, or nails.
The following sites were affected: trunk (... | C17 |
2,096 | 3,369 | Erythema infectiosum and pregnancy-related complications
Erythema infectiosum, an acute, communicable viral disease with a highly distinctive exanthem, follows the usual course of a self-limiting benign disease.
In pregnant women, however, it may be associated with fetal death and nonimmune hydrops fetalis.
Because... | C17 |
2,097 | 4,447 | Chronic urticaria exacerbated by the antioxidant food preservatives, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).
Two patients with chronic idiopathic urticaria in whom remissions were achieved with dye- and preservative-elimination diet had exacerbations of their urticaria when they were challen... | C17 |
2,098 | 5,598 | Multiple myeloma and bullous lichenoid lesions: an unusual association.
Many associations of lichenoid reactions have been described but this case appears to be a previously unreported association--with multiple myeloma.
This case also demonstrates the necessity of a mucosal biopsy with adequate hematologic and serol... | C17 |
2,099 | 8,923 | IgG subclasses in the serum and skin in subacute cutaneous lupus erythematosus and neonatal lupus erythematosus.
IgG subclasses differ in their biologic and chemical properties, such as complement fixation, protein and cellular binding, and placental transfer.
In this study, IgG subclasses of anti-Ro/SSA antibodies i... | C17 |
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