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2,100 | 4,589 | Lymphocyte adhesion to psoriatic dermal endothelium: mechanism and modulation.
Psoriasis is characterized by the hyperproliferation of keratinocytes in the epidermis and the accumulation of activated CD4+ T lymphocytes in the upper dermis.
We have recently tested the hypothesis that the abnormal endothelial prolifera... | C17 |
2,101 | 9,799 | Digital imaging techniques in dermatology.
Digital imaging is a versatile technique that has been infrequently used in dermatology to record visual images.
We have used this technology for 10 patients to follow cutaneous lesions, including alopecia mucinosa, psoriasis, and dysplastic nevi.
The setup included a perso... | C17 |
2,102 | 8,232 | Chronic sinusitis and the yellow nail syndrome.
Diagnosing syndromes that include chronic sinusitis can expedite the management of both conditions.
Yellow nail syndrome is usually described as the combination of yellow nails, lymphoedema and often respiratory manifestations such as chronic sinusitis, bronchiectasis a... | C17 |
2,103 | 6,306 | Antinuclear matrix antibody. Hidden antinuclear antibody in patients with connective tissue diseases.
A total of 435 serum samples from patients with different rheumatic diseases were screened for the presence of autoantibody to nuclear matrix components by indirect immunofluorescence on 0.1 mol/L HCl extracted HEp-2 ... | C17 |
2,104 | 7,230 | The protective effect of the oral contraceptive pill on rheumatoid arthritis: an overview of the analytic epidemiological studies using meta-analysis.
The oral contraceptive pill (OCP) has been implicated as having a protective effect on the development of rheumatoid arthritis (RA).
The results of 12 studies have now... | C17 |
2,105 | 594 | Resolution of inferior vena cava syndrome after embolization of a hepatic adenoma.
A 77-year-old man presented with severe pruritus and massive lower body edema.
Computerized axial tomography of the abdomen showed a large hepatic mass compressing the inferior vena cava, and a liver biopsy specimen showed hepatic aden... | C17 |
2,106 | 2,735 | A forme fruste of Marfan's syndrome: case history.
A thirty nine year old woman presented with multiple aneurysms and dissections of the arterial system secondary to cystic medial necrosis is presented.
After assessment of the family history a diagnosis of a forme fruste of Marfan's syndrome was made.
Preoperative c... | C17 |
2,107 | 3,313 | The inhibition of NK cell function by azathioprine during the treatment of patients with rheumatoid arthritis.
Treatment with azathioprine of patients with rheumatoid arthritis leads to a dramatic reduction in the 4 h NK cytotoxicity against K562 cells.
The 24 h cytotoxicity against K562 and U937 cells, however, rema... | C17 |
2,108 | 6,008 | Normeperidine-induced seizures in hereditary coproporphyria.
Seizures are common in acute exacerbations of hepatic porphyria, even though the etiology is not identified in most cases.
We have reported a case of normeperidine-induced seizures in a patient with hereditary coproporphyria.
Although meperidine is commonl... | C17 |
2,109 | 861 | A method for the determination of UVA protection for normal skin.
Although the UVB portion of the electromagnetic spectrum (290 to 320 nm) is responsible for most of the harmful effects of sunlight on the skin, wavelengths in the UVA region also contribute to photodamage.
A simple and rapid clinical test, the sun pro... | C17 |
2,110 | 25 | Laser photodynamic therapy for papilloma viral lesions.
Photodynamic therapy was tested for its therapeutic efficacy in eradicating rabbit papilloma warts.
The wild-type viral warts suspension was used to induce treatable papilloma warts in the cutaneous tissue of Dutch Belted rabbits.
The photosensitizing agents us... | C17 |
2,111 | 4,326 | Intralesional interferon therapy for basal cell carcinoma.
In a clinical trial of 172 patients at four medical centers, interferon alfa-2b (1.5 x 10(6) IU) or a placebo was injected directly into biopsy-proved noduloulcerative or superficial basal cell carcinomas three times weekly for 3 weeks, for a cumulative dose o... | C17 |
2,112 | 8,180 | IgG antibodies from patients with bullous pemphigoid bind to localized epitopes on synthetic peptides encoded by bullous pemphigoid antigen cDNA.
Bullous pemphigoid (BP) is an autoimmune blistering disease characterized in part by the presence of tissue-bound and circulating antibodies specific for basement membrane z... | C17 |
2,113 | 2,295 | Marfan syndrome in China: a collective review of 564 cases among 98 families.
This is a collective review of 564 patients with Marfan syndrome among 98 pedigrees reported from 18 provinces and cities in China over a 37-year period from 1951 to 1987.
A positive family history of Marfan syndrome was found in 74.3% of t... | C17 |
2,114 | 8,213 | Identification and isolation of a phospholipase A2 activating protein in human rheumatoid arthritis synovial fluid: induction of eicosanoid synthesis and an inflammatory response in joints injected in vivo.
Eicosanoids are important mediators of the destructive arthropathy observed in rheumatoid arthritis.
The rate-l... | C17 |
2,115 | 63 | Autologous mixed lymphocyte reaction is reduced in patients with psoriasis.
The autologous mixed lymphocyte reaction (auto-MLR) was studied to test the interactions between immunocompetent cells in patients with psoriasis.
The auto-MLR in 20 patients with psoriasis was significantly lower than in 16 normal controls.
... | C17 |
2,116 | 843 | Condylomata acuminata in children: frequent association with human papillomaviruses responsible for cutaneous warts.
To identify the papillomavirus types associated with condylomata acuminata in children and to evaluate their mode of transmission, we studied 32 children with anogenital warts.
External condylomata wer... | C17 |
2,117 | 866 | Treatment of hirsutism with the pure antiandrogen flutamide.
The effectiveness of the antiandrogen flutamide in combination with an oral contraceptive was studied in 20 patients with moderate to severe hirsutism.
Eight patients had no previous therapy, whereas 12 had failed to respond to oral contraceptives, spironol... | C17 |
2,118 | 4,456 | The role of antihistamines in the treatment of chronic urticaria.
For many years, H1 antihistamines have been the primary management option for urticaria.
However, undesirable side effects, particularly daytime sedation, have limited the usefulness of these classic antihistamines.
A new class of peripherally acting,... | C17 |
2,119 | 804 | Activation pathways of synovial T lymphocytes. Expression and function of the UM4D4/CDw60 antigen.
Accumulating evidence implicates a central role for synovial T cells in the pathogenesis of rheumatoid arthritis, but the activation pathways that drive proliferation and effector function of these cells are not known.
... | C17 |
2,120 | 4,466 | It is children with atopic dermatitis who develop asthma more frequently if the mother smokes.
We elicited symptoms of atopic dermatitis (AD) and of asthma from 620 children who were themselves nonsmokers, were aged 1 to 17 years, and had been consecutively referred to an allergy clinic.
A histamine bronchial-challen... | C17 |
2,121 | 5,087 | The natural history of Peyronie's disease.
The natural history of Peyronie's disease was evaluated in 97 men by means of a questionnaire.
Disease duration ranged from 3 months to 8 years.
Questions addressed pain, bending, ability for intercourse, over-all effect of the disease, psychological effects, treatments rec... | C17 |
2,122 | 6,932 | Thyrotoxicosis induced by topical iodine application.
We describe an elderly man who was admitted with congestive cardiac failure and found to have thyrotoxicosis.
He did not have goiter, and he had normal radioiodine uptake in his neck.
Serum iodine levels were elevated, explaining the lack of increase in radioiodi... | C17 |
2,123 | 4,358 | Widespread flat warts associated with human papillomavirus type 5: a cutaneous manifestation of human immunodeficiency virus infection.
Numerous flat and tinea versicolor-like warts developed on the face, trunk, and upper extremities of a 10-year-old boy with human immunodeficiency virus infection.
Nucleic acid analy... | C17 |
2,124 | 3,608 | Uremic pruritus in patients on hemodialysis or continuous ambulatory peritoneal dialysis (CAPD). The role of plasma histamine and skin mast cells.
Fifty-four uremic patients (26 patients were maintained on continuous ambulatory peritoneal dialysis [CAPD] and 28 on hemodialysis [HD]) were screened for pruritus and plas... | C17 |
2,125 | 7,007 | The post-occlusive hyperemic response in patients with systemic sclerosis.
We investigated post-ischemic hyperreactive cutaneous blood flow in patients with primary Raynaud's phenomenon and Raynaud's phenomenon secondary to systemic sclerosis (SSc).
Reactive hyperemia was measured over a locally warmed area of skin, ... | C17 |
2,126 | 801 | Isolation of a human epidermal cDNA corresponding to the 180-kD autoantigen recognized by bullous pemphigoid and herpes gestationis sera. Immunolocalization of this protein to the hemidesmosome.
Autoantibodies present in the sera of patients with bullous pemphigoid (BP) bind to the basement membrane zone of normal hum... | C17 |
2,127 | 8,807 | Estrogen receptor localization in normal and neoplastic epithelium of the uterine cervix.
To investigate the estrogen receptor (ER) status of cells during carcinogenesis of the uterine cervix, the immunohistochemical reactivity for a monoclonal anti-ER antibody (H 222) was studied in 26 normal cervical specimens, 21 c... | C17 |
2,128 | 9,915 | The temporomandibular joint in rheumatoid arthritis. Correlations between clinical and computed tomography features.
Clinical and computed tomography (CT) examination of the temporomandibular joint (TMJ) was performed in 26 patients with rheumatoid arthritis (RA) and 26 control subjects.
Each examination was scored.
... | C17 |
2,129 | 5,256 | Buruli ulcer in Benin
In a study of 28 patients with Mycobacterium ulcerans infection (Buruli ulcer) in Oinhi, Benin, it became clear that the disease can regress as well as progress, and that patients can have lesions of different stages simultaneously.
A system of disease staging was introduced (I = subcutaneous n... | C17 |
2,130 | 9,785 | A controlled trial of clobetasol propionate ointment 0.05% in the treatment of experimentally induced Rhus dermatitis.
We studied the effectiveness of clobetasol propionate ointment 0.05% in experimentally induced Rhus dermatitis.
Clobetasol rapidly decreased the vesiculation at each treated site, although the effect... | C17 |
2,131 | 3,073 | Diminished incidence of severe rheumatoid arthritis associated with oral contraceptive use.
It has been suggested that the negative association between rheumatoid arthritis (RA) and oral contraceptive (OC) use might be limited to the more severe forms of RA.
To investigate this further, we studied 121 consecutive fem... | C17 |
2,132 | 3,075 | Cellular immune response toward human articular chondrocytes. T cell reactivities against chondrocyte and fibroblast membranes in destructive joint diseases.
Articular cartilage is one of the major targets in destructive joint diseases in humans.
We studied cellular immune reactions against cartilage cell-surface mem... | C17 |
2,133 | 4,588 | The role of epidermal cytokines in inflammatory skin diseases.
Cytokines (hormone-like polypeptide mediators) play a major role in inflammatory and immunoregulatory responses.
Skin, and particularly keratinocytes in the skin, represent a potent source for many cytokines, including interleukins 1, 6, 8, and the hemopo... | C17 |
2,134 | 8,572 | Cimetidine suppresses chemically induced experimental hepatic porphyria.
The ability of cimetidine to reduce the activity of hepatic aminolevulinic acid synthase (ALA-S) was examined in allylisopropyl acetamide (AIA) treated porphyric adult rats.
A dose of 20 mg cimetidine/100 gm body weight resulted in a 50% decreas... | C17 |
2,135 | 5,137 | Indirect revascularization of the lower extremity by means of microvascular free-muscle flap--a preliminary report.
We describe the treatment of a patient with end-stage peripheral vascular disease and ischemic ulceration of the lower extremity in whom an obliteration of the distal arterial bed precluded conventional ... | C17 |
2,136 | 872 | Dermatoses associated with sterile lytic bone lesions.
In recent years several dermatoses, palmoplantar pustulosis, acne fulminans, and Sweet's syndrome, have been associated with sterile lytic bone lesions.
This article discusses the clinical, laboratory, and histologic findings of these disorders and postulates a c... | C17 |
2,137 | 862 | Pigmented Bowen's disease arising from pigmented seborrheic keratoses.
We report three cases of pigmented Bowen's disease that clinically and histologically had features of seborrheic keratoses.
We speculate about the mechanism of pigmentation in these lesions and suggest that they arise from pigmented seborrheic ker... | C17 |
2,138 | 2,063 | Surgical management of palmar hyperhidrosis.
Hyperhidrosis is an idiopathic pathologic condition characterized by excessive sweating beyond that required to cool the body.
Disturbance of the central nervous system, endocrine system, or obesity has been associated with this condition.
Patients have a history of sever... | C17 |
2,139 | 7,670 | Muscle involvement in the scleroderma syndromes.
Muscle involvement was identified in 14 patients with scleroderma or a connective tissue disease overlap syndrome with predominant features of scleroderma.
Patients presented with symmetrical proximal weakness indistinguishable from other inflammatory myopathies.
Crea... | C17 |
2,140 | 8,704 | Non-invasive monitoring of finger arterial pressure in patients with Raynaud's phenomenon: effects of exposure to cold.
We studied the effects of exposure to cold on finger arterial pressure (FAP) measured by a finger arterial pressure monitor in 15 patients with Raynaud's phenomenon and in 15 healthy volunteers.
The... | C17 |
2,141 | 735 | The Oxford knee replacement. A review from an independent centre.
We present a study of 67 Oxford bicompartmental total knee replacements performed at a district general hospital.
In this general orthopaedic unit, 57 of the knees (85%) had significant relief of pain with a mean flexion range of 95 degrees and a mean ... | C17 |
2,142 | 9,031 | Arthropathy of Down syndrome.
A juvenile rheumatoid arthritis-like arthropathy has previously been documented in 12 patients with Down syndrome.
An additional 9 patients are described and the literature is reviewed.
It is unknown whether these patients have juvenile rheumatoid arthritis or a unique arthropathy in li... | C17 |
2,143 | 4,451 | The role of histamine in allergic diseases.
Histamine, which is stored mainly in mast cells and basophils, is a prominent contributor to allergic disease.
Elevations in plasma or tissue histamine levels have been noted during anaphylaxis and experimental allergic responses of the skin, nose, and airways.
Of the four... | C17 |
2,144 | 871 | Treatment of aggressive keratoacanthomas by radiotherapy.
Keratoacanthomas infrequently are treated by radiotherapy.
However, keratoacanthomas that are recurrent after surgical excision or whose resection would result in cosmetic deformity may benefit from radiotherapy.
Between January 1970 and June 1988, 29 such ke... | C17 |
2,145 | 62 | Neutrophil zinc levels in psoriasis and seborrhoeic dermatitis.
The median zinc content of neutrophils was significantly reduced in 16 patients with psoriasis in comparison to both normal controls and six patients with seborrhoeic dermatitis (P less than 0.05).
This reduction was unrelated to the extent of skin invol... | C17 |
2,146 | 3,786 | Retroperitoneal air after routine hemorrhoidectomy. Report of a case.
Retroperitoneal air as a complication after routine hemorrhoidectomy has not been reported in the literature.
This occurred recently after hemorrhoidectomy in a 34-year-old patient receiving glucocorticoid therapy for rheumatoid arthritis.
Adverse... | C17 |
2,147 | 60 | Elastic fibre damage induced by low-dose D-penicillamine.
We have studied 23 patients receiving penicillamine for the treatment of rheumatoid arthritis to determine the prevalence of penicillamine-induced elastosis.
One female patient had pseudoxanthoma elasticum-like skin changes and bramble-bush elastosis without c... | C17 |
2,148 | 827 | Use of monoclonal antibody KP1 for identifying normal and neoplastic human mast cells.
The monoclonal antibody KP1 (CD68) was used to stain normal and neoplastic monocytes and macrophages in routinely processed, paraffin wax embedded tissue: mast cells also exhibited strong, consistent cytoplasmic immunoreactivity.
L... | C17 |
2,149 | 8,755 | Development of renal scars in children: missed opportunities in management. South Bedfordshire Practitioners' Group.
OBJECTIVE--To assess the antecedent medical care of children with renal scars.
DESIGN--Retrospective study of both general practice and hospital records.
SETTING--12 Group practices in south Bedfordsh... | C17 |
2,150 | 346 | Prevalence and sources of sensitization to emulsifiers: a clinical study.
737 patients with suspected cosmetic- or medicament-related contact dermatitis were patch tested with 6 emulsifier agents: triethanolamine, cetyl stearyl alcohol, sorbitan sesquioleate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sor... | C17 |
2,151 | 5,584 | Bilateral keloid-like myofibroblastic proliferations of the cornea in children.
Two 6-month-old white boys developed localized multifocal white nodules of the anterior corneal stroma without evidence of antecedent trauma, inflammatory disease, or familial occurrence.
The first patient had bilateral lesions initially;... | C17 |
2,152 | 851 | Incidence of cutaneous T cell lymphoma and other rare skin cancers in a defined population.
Between 1970 and 1984 in Rochester, Minnesota, rare skin cancers developed in 15 local residents: cutaneous T cell lymphoma (six subjects), dermatofibrosarcoma protuberans (four), adenocarcinoma of sweat glands (two), Merkel ce... | C17 |
2,153 | 9,913 | Phenotypic characteristics of dissociated mononuclear cells from rheumatoid synovial membrane.
The phenotypic characteristics of enzymatically dissociated synovial membrane mononuclear cells from 8 patients (14 samples) with rheumatoid arthritis (RA) were assessed by fluorescence activated flow cytometry and compared ... | C17 |
2,154 | 34 | Osteoma of the middle ear. Report of a case.
Osteomas of the middle ear are rare.
We report a case of a 7-year-old boy with osteoma originating from the pyramidal eminence, combined with congenital cholesteatoma.
The osteoma and cholesteatoma were successfully removed by tympanomastoidectomy.
The long process of th... | C17 |
2,155 | 9,919 | Specificity of anti-Scl-70 antibodies in scleroderma: increased sensitivity of detection using purified DNA topoisomerase I from calf thymus.
A large scale purification of DNA topoisomerase I from calf thymus was obtained using the combinations of 62% ammonium sulfate precipitation, Biorex 70, hydroxylapatite and phen... | C17 |
2,156 | 67 | Effects of haem arginate on variegate porphyria.
Four patients with variegate porphyria (VP) were treated with repeated haem arginate infusions daily for 4 days and then weekly for 4 weeks.
After the initial four daily doses of haem arginate (haem 3 mg/kg), the excretion of faecal protoporphyrin (mean 579 nmol/g dry ... | C17 |
2,157 | 4,604 | Sodium lauryl sulphate for irritant patch testing--a dose-response study using bioengineering methods for determination of skin irritation.
The dose-response relationship in patch testing with sodium lauryl sulphate (SLS) was studied.
The irritant skin response was quantified by visual scoring as well as by the follo... | C17 |
2,158 | 7,009 | Diffusing capacity of the lung and nifedipine in systemic sclerosis.
Lung involvement in systemic sclerosis may be due in part to a functional abnormality of the pulmonary vasculature.
To investigate the possible role of a pulmonary vasospastic process in this disorder, 21 non-smoking patients who had no evidence of ... | C17 |
2,159 | 898 | Multiple oral and skin lesions occurring after treatment with penicillin.
A case of erythema multiforme has been presented.
Erythema multiforme may be a self-limiting or chronic disease, of varying severity.
The disease is of significance to dental practitioners who may be called on to establish a diagnosis and prov... | C17 |
2,160 | 4,333 | Contact dermatoses from disposable glove use: a review.
Contact dermatoses from disposable gloves are being reported with greater frequency.
A variety of eruptions can occur.
These have become increasingly relevant for dermatologists, who for most procedures now use disposable gloves.
This article represents a revi... | C17 |
2,161 | 4,592 | Immunology of AIDS related to psoriasis.
The association of severe psoriasis with HIV infection, which dysregulates and destroys the human immune system, supports the hypothesis that psoriasis is an immunologically mediated disease.
Psoriasis and Kaposi's sarcoma share angiogenesis as basic early findings and could b... | C17 |
2,162 | 9,931 | Synthesis and release of phospholipase A2 by unstimulated human articular chondrocytes.
High activity of proinflammatory, type II phospholipase A2 (PLA2) was found in synovial fluids (SF) in inflammatory arthritis.
In search for the sources of this PLA2, we cultured human articular chondrocytes and cartilage explants... | C17 |
2,163 | 7,011 | IgG and IgA antibodies to the collagen-like region of C1q in rheumatoid vasculitis.
We investigated the presence of IgG and IgA antibodies to C1q in serum samples from 80 patients with rheumatoid arthritis (RA), 31 patients with rheumatoid vasculitis, and 80 healthy controls.
IgG and IgA antibodies to C1q, as measure... | C17 |
2,164 | 8,328 | Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia.
BACKGROUND and METHODS.
We describe five patients with underlying neoplasms in whom painful mucosal ulcerations and polymorphous skin lesions developed, usually with progression to blistering eruptions on the trunk and extremitie... | C17 |
2,165 | 4,584 | Psoriasis vulgaris: a genetic approach.
Evidence for a genetic contribution in psoriasis comes from direct examination of a large segment of the population in an isolated island environment, epidemiologic and questionnaire studies presented to psoriatic patients, twin studies collected from the literature and from twi... | C17 |
2,166 | 3,078 | Use of molecular cloning methods to map the distribution of epitopes on topoisomerase I (Scl-70) recognized by sera of scleroderma patients.
We report the initial molecular characterization of the autoimmune response against DNA topoisomerase I (topo I; Scl-70).
Sera from 36 patients with scleroderma and 4 healthy co... | C17 |
2,167 | 7,233 | Is baldness a risk factor for coronary artery disease? A review of the literature.
A literature search identified eight articles containing data on both baldness and coronary artery disease (CAD).
Three of these articles described case-control studies that showed a positive relationship between baldness and CAD when ... | C17 |
2,168 | 464 | Measuring vibration sensations with graduated tuning fork. Simple and reliable means to detect diabetic patients at risk of neuropathic foot ulceration.
To find a simple and reliable means to measure vibration sensations, 189 diabetic patients and 88 control subjects were tested at different sites with a graduated tun... | C17 |
2,169 | 2,753 | Adverse reactions to heparin [clinical conference]
Heparin is a medication that has gained widespread use in clinical medicine as the therapy of choice for acute anticoagulation in the prevention and treatment of thromboembolic disease.
Therapy with heparin is associated with many potential adverse side effects.
Hep... | C17 |
2,170 | 3,077 | Specificity of antibodies to type II collagen in rheumatoid arthritis.
To reassess the role of autoantibodies to type II collagen in the pathogenesis of diseases, we studied antibodies from patients with rheumatoid arthritis (RA) and from patients with relapsing polychondritis for species specificity and collagen type... | C17 |
2,171 | 9,790 | Papular-purpuric "gloves and socks" syndrome.
We report five cases of an acute, self-limiting dermatosis that has not been previously described.
It consists of a pruritic edema and erythema of the hands and feet in a gloves-and-socks distribution and is associated with oral lesions and fever.
The clinical course is ... | C17 |
2,172 | 8,231 | Auro-nasopharyngeal polyp and cholesteatoma.
We report the association of an auronasopharyngeal polyp arising in a congenitally abnormal middle ear and Eustachian tube.
Subsequently, ten years after removal of the polyp and insertion of a ventilation tube, there was recurrence of the polyp in association with cholest... | C17 |
2,173 | 7,629 | Large arteries involvement in scleroderma--a case report.
The authors describe a thirty-nine-year-old woman patient presenting with progressive systemic sclerosis and an unusual angiographic picture of an impairment of large arteries, which in their opinion is due to the primary disease.
The review literature reports... | C17 |
2,174 | 2,987 | Acute renal failure due to ciprofloxacin.
Acute renal failure developed in three patients within a few days of starting ciprofloxacin hydrochloride therapy.
An allergic interstitial nephritis was suggested by fever and eosinophiluria in one patient and by erythema multiforme in another.
A kidney biopsy specimen conf... | C17 |
2,175 | 6,013 | Cytophagic histiocytic panniculitis evolving into total lipodystrophy.
A 15-year-old boy had persistent fever with severe neutropenia, thrombocytopenia, coagulation disorder, and marked elevation of lactate dehydrogenase values.
A diagnosis of cytophagic histiocytic panniculitis was made after repeated skin biopsies.... | C17 |
2,176 | 9,781 | Anti-(U1) small nuclear RNA antibodies in anti-small nuclear ribonucleoprotein sera from patients with connective tissue diseases.
Small nuclear ribonucleoprotein (snRNP) particles are a class of RNA-containing particles in the nucleus of eukaryotic cells.
Sera from patients with connective tissue diseases often cont... | C17 |
2,177 | 5,021 | Skin blisters as a manifestation of oxazepam toxicity.
A 75 year-old comatous patient was admitted after ingestion of 200 mg oxazepam.
Skin blisters, attributed to oxazepam toxicity, appeared on the left forearm the following day and regressed spontaneously nine days later. | C17 |
2,178 | 4,268 | Effect of chronic treatment with the glucocorticoid antagonist RU 486 in man: toxicity, immunological, and hormonal aspects.
Suppression of immune function was traditionally thought to occur only with pharmacological levels of glucocorticoids.
However, recent studies in rodents have suggested that glucocorticoids exe... | C17 |
2,179 | 4,586 | Lymphocyte chemoattractants in psoriasis and normal skin.
The local production of lymphocyte attractants may influence both physiologic lymphocyte trafficking in the skin as well as the infiltration of these cells in pathologic states.
Recent evidence for the production of acidic lipid lymphocyte chemoattractants, pa... | C17 |
2,180 | 870 | Hydroxychloroquine is effective therapy for control of cutaneous sarcoidal granulomas.
Cutaneous sarcoidosis often responds poorly to topical and intralesional corticosteroids but may respond to moderate to high doses of oral corticosteroids.
To avoid the use of systemic corticosteroids, we treated 17 patients with c... | C17 |
2,181 | 9,882 | Sensitivity of effect variables in rheumatoid arthritis: a meta-analysis of 130 placebo controlled NSAID trials [published erratum appears in J Clin Epidemiol 1991;44(6):613]
In a meta-analysis of placebo controlled NSAID trials, the sensitivity of the effect variables was calculated as the correlation coefficient and... | C17 |
2,182 | 873 | The relationship of pemphigus to neoplasia.
A statistically increased incidence of malignancy has been observed in patients with pemphigus.
A review of the literature reveals 42 cases of nonthymic malignancies and 18 cases of thymic malignancies.
A significant predominance of men, with mean age at onset of 50 years,... | C17 |
2,183 | 9,032 | Interleukin-2 immunotherapy in children.
Immunotherapy with interleukin (IL)-2 possesses great potential in the treatment of immune-mediated diseases and cancers.
However, only a few reports on a small number of children have appeared in the literature.
From March 1988 to March 1989, 11 children and adolescents were... | C17 |
2,184 | 856 | The prognosis of contact dermatitis.
This article reviews the prognosis of contact dermatitis, particularly of occupational contact dermatitis.
Most studies document a poor prognosis for occupational and nonoccupational contact dermatitis.
The prognoses of occupational and nonoccupational contact dermatitis, irritan... | C17 |
2,185 | 736 | The incidence of deep vein thrombosis after cementless and cemented knee replacement.
The incidence of deep vein thrombosis in 244 patients who had total knee replacement has been studied.
In 120 the prosthesis was cemented and in 124 it was cementless.
In all cases the replacement was primary and a porous-coated pr... | C17 |
2,186 | 7,232 | Health status reports in the care of patients with rheumatoid arthritis.
We examined the use of formal health status reports every 3 months over 1 year in the clinical care of patients with rheumatoid arthritis (RA).
The reports consisted of single-page, computer-generated summaries of scores derived from either the ... | C17 |
2,187 | 5,337 | A chronic granulomatous syndrome of unknown origin.
A small clinically distinct group of patients with widespread tissue granulomata are described.
The principal presenting symptoms are malaise, fever, and weight loss, although a wide variety of complaints are documented.
Pulmonary involvement is uncommon.
The gran... | C17 |
2,188 | 8,121 | Marjolin's ulcer: a review and reevaluation of a difficult problem.
The formation of an epidermoid carcinoma in nonhealing scar tissue, a Marjolin's ulcer, is a well described neoplasm.
These lesions are, however, frequently overlooked and often inadequately treated.
This paper reviews six cases of scar-tissue carci... | C17 |
2,189 | 849 | Neutrophilic dermatosis with myelodysplastic syndrome: nuclear segmentation anomalies of neutrophils in the skin lesion and in peripheral blood.
Neutrophilic dermatosis developed in two patients with myelodysplastic syndrome.
Biopsy specimens of their skin lesions showed marked infiltration by neutrophils with nuclea... | C17 |
2,190 | 9,916 | Adherent synovial cells from nonrheumatoid arthritis do not release interleukin 1 beta and prostaglandin E2 spontaneously in longterm culture.
Adherent synovial cells from both 13 patients without rheumatoid arthritis (RA) (gout, osteoarthritis and meniscal lesion) and 8 patients with RA consisted of dendritic cells, ... | C17 |
2,191 | 4,334 | Prevention of occupational contact dermatitis.
Contact dermatitis is the most frequent type of occupational skin disease.
Although prevention of contact dermatitis in the workplace should ideally be accomplished through total elimination of cutaneous exposure to hazardous substances, this is often not feasible.
Ther... | C17 |
2,192 | 845 | Photochemotherapy improves chronic cutaneous graft-versus-host disease.
We have used oral psoralen photochemotherapy (PUVA) to treat four patients with chronic graft-versus-host disease of the skin, oral mucosa, and liver, who had responded only partially to long-term immunosuppressive therapy (prednisolone, cyclospor... | C17 |
2,193 | 4,587 | Interleukin-1 in human skin: dysregulation in psoriasis.
Cytokine dysregulation is an attractive concept to explain many of the observed abnormalities in psoriasis.
IL-1, in particular, can potentiate immune cellular activation, activate fibroblasts, and increase endothelial cell adhesiveness to leukocytes.
Here, we... | C17 |
2,194 | 7,014 | Association of labial salivary gland histopathology with clinical and serologic features of connective tissue diseases.
Focal sialadenitis is now widely accepted as an objective criterion for the oral component of Sjogren's syndrome (xerostomia).
We investigated the association between labial salivary gland histopath... | C17 |
2,195 | 4,606 | Experimental models for psoriasis.
Evidence suggests that inherent in skin of psoriatic subjects are cells, architectural structures, and/or mediators, which are, at a minimum, responsible for its hyperproliferative epidermis.
An objective of our laboratory has been to establish an in vitro definition of this inheren... | C17 |
2,196 | 7,190 | Two different point G to A mutations in exon 10 of the porphobilinogen deaminase gene are responsible for acute intermittent porphyria.
Two mutations of the porphobilinogen (PBG) deaminase gene resulting in cross-reacting immunological material (CRIM) positive forms of acute intermittent porphyria (AIP) have been iden... | C17 |
2,197 | 8,739 | Pachyonychia congenita complicated by hidradenitis suppurativa: a family study.
A family is described in which five of the six members with the Jackson-Lawler type of pachyonychia congenita also had varying degrees of hidradenitis suppurativa.
We suggest an association between this type of pachyonychia congenita and ... | C17 |
2,198 | 7,335 | End-stage renal disease--is infrainguinal limb revascularization justified?
Reports of reconstructive surgery for peripheral vascular disease have been relatively uncommon in patients with end-stage renal disease.
Between 1980 and 1989, 39 patients with end-stage renal disease underwent revascularization of 56 limbs.... | C17 |
2,199 | 5,166 | The epidemiology and natural history of pressure ulcers in elderly nursing home residents
We analyzed prospective data from 19,889 elderly residents of 51 nursing homes from 1984 to 1985 to determine the prevalence, incidence, and natural history of pressure ulcers.
Among all residents admitted to nursing homes, 11.... | C17 |
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