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5,800 | 3,199 | Doppler echocardiographic evaluation of pulmonary artery flow after modified Fontan operation: importance of atrial contraction.
Doppler echocardiography was used to evaluate blood flow in the pulmonary artery in 14 patients 2 to 42 months (mean (SD) 17 (12) months) after a modified Fontan operation incorporating a di... | C16 |
5,801 | 9,025 | Diagnosis and management of infantile marfan syndrome.
Marfan syndrome is infrequently diagnosed early in infancy.
The experience of the authors with 22 severely affected infants diagnosed as having Marfan syndrome in the first 3 months of life is described and the literature on 32 additional infants with Marfan synd... | C16 |
5,802 | 9,448 | A total artificial heart for neonates allowing bridging to transplantation.
Since the early 1980s, a rapid increase in successful pediatric heart transplantation has improved the chance of survival for many children suffering from otherwise fatal cardiomyopathies or congenital cardiac defects.
During the last 5 years... | C16 |
5,803 | 4,409 | Cardiac teratogenesis of trichloroethylene and dichloroethylene in a mammalian model.
Recent epidemiologic studies have demonstrated a greater than expected number of pediatric patients with congenital heart disease in areas where drinking water was contaminated by halogenated aliphatic hydrocarbons.
Trichloroethylen... | C16 |
5,804 | 4,335 | Ptychotropism as a cutaneous feature of the CHILD syndrome.
The hallmark of the CHILD syndrome is a unilateral ichthyosiform nevus that displays a pronounced affinity for the body folds.
For this phenomenon the term ptychotropism is proposed.
The expression is composed from the Greek words ptyche (fold) and trope (a... | C16 |
5,805 | 6,460 | Ocular pathologic features of arteriohepatic dysplasia (Alagille's syndrome).
Arteriohepatic dysplasia (Alagille's syndrome), an autosomal dominant condition involving jaundice caused by a developmental scarcity of intrahepatic bile ducts, has characteristic cardiovascular, skeletal, facial, and ocular features that d... | C16 |
5,806 | 3,537 | Partial anomalous pulmonary venous return.
Anomalous pulmonary venous return from the left lung is an extremely rare condition that is reported sporadically and in general in case reports.
From 1964 through 1988, we identified 13 patients with this condition, all of whom underwent surgical correction.
This represent... | C16 |
5,807 | 9,814 | Increased birth prevalence of cardiac defects in Yuma, Arizona
A systematic study was undertaken to estimate the birth prevalence of congenital heart disease because there was a clinical impression that a disproportionate number of cases occurred in Yuma, Arizona.
Control data were obtained from Sierra Vista, Arizon... | C16 |
5,808 | 2,479 | Cystic fibrosis mutations in North American populations of French ancestry: analysis of Quebec French-Canadian and Louisiana Acadian families.
A 3-bp deletion (delta F508) in the cystic fibrosis (CF) gene is the mutation on the majority of CF chromosomes.
We studied 112 CF families from North American populations of ... | C16 |
5,809 | 2,481 | Linkage relationship of X-linked juvenile retinoschisis with Xp22.1-p22.3 probes.
Linkage analysis was performed to evaluate the relationship between the locus for X-linked juvenile retinoschisis (RS) and five X-chromosomal markers-RC8 (DXS9), SE3.2L (DXS16), 99-6 (DXS41), D2 (DXS43), and 782 (DXS85)-all mapped to the... | C16 |
5,810 | 8,357 | Internuclear ophthalmoplegia in the Chiari type II malformation.
We describe 3 cases of Chiari type II malformation presenting with bilateral internuclear ophthalmoplegia (INO).
Although prominent, the INO was not an isolated sign in any of the patients; superimposed abduction paresis was present in 2, and deficits i... | C16 |
5,811 | 5,649 | Development and validation of an index for scoring baseline respiratory disease in the very low birth weight neonate. Severity Index Development and Validation Panels and Newborn Lung Project.
An accurate description of the population at risk for neonatal chronic lung disease is clearly of prime importance for compara... | C16 |
5,812 | 6,335 | Adenocarcinoma arising in Barrett's esophagus after total gastrectomy
A 64-yr-old Japanese male who underwent a partial gastrectomy for a duodenal ulcer at the age of 21, a total resection of the remnant stomach for a stomal ulcer at age 25, and in whom Barrett's esophagus was diagnosed at age 47, was found to have a... | C16 |
5,813 | 2,523 | The association of intrapartum asphyxia in the mature fetus with newborn behavior.
A matched cohort study of mature newborns with biochemically determined intrapartum fetal asphyxia and mature newborns with normal blood gas and acid-base assessments at delivery were studied to demonstrate the effect of fetal asphyxia ... | C16 |
5,814 | 9,603 | Changes in circulating alphafetoprotein following administration of mifepristone in first trimester pregnancy.
The occurrence of fetomaternal haemorrhage was investigated in 30 women by measuring maternal serum alphafetoprotein (AFP) levels before and after the administration of mifepristone (RU 486) for termination o... | C16 |
5,815 | 7,105 | Atenolol in essential hypertension during pregnancy
OBJECTIVE--To determine the effect of atenolol on the outcome of pregnancy in women with essential hypertension.
DESIGN--Prospective, randomised, double blind, placebo controlled study.
SETTING--Hospital clinic.
PATIENTS--33 Women with mild essential hypertension... | C16 |
5,816 | 9,058 | Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum.
Respiratory distress and progressive lung destruction in cystic fibrosis can be attributed to bacterial persistence and the accumulation of viscous purulent secretions in the airways.
More than 30 yr ago it was suggested that the large amounts... | C16 |
5,817 | 9,440 | Development of a new transvenous patent ductus arteriosus occlusion technique using a shape memory polymer.
A novel percutaneous patent ductus arteriosus (PDA) occlusion technique, without the potential problems associated with conventional techniques, has been long awaited.
The development of a novel transvenous PDA... | C16 |
5,818 | 3,509 | Late potentials and inducible ventricular tachycardia in surgically repaired congenital heart disease.
We compared signal-averaged electrocardiography with invasive electrophysiological study in patients after surgical repair of congenital heart disease to determine if potentially useful correlations exist between the... | C16 |
5,819 | 5,828 | Streamlined approach to creating yeast artificial chromosome libraries from specialized cell sources.
The study of tumor-specific chromosomal abnormalities has been severely impeded by an inability to link cytogenetic to molecular data.
Restriction fragment length polymorphism mapping of any particular chromosomal re... | C16 |
5,820 | 4,428 | Is banding of the pulmonary trunk obsolete for infants with tricuspid atresia and double inlet ventricle with a discordant ventriculoarterial connection? Role of aortic arch obstruction and subaortic stenosis
Banding the pulmonary trunk may exacerbate or promote the development of subaortic stenosis in patients with ... | C16 |
5,821 | 5,215 | Adenocarcinoma arising in Barrett's esophagus.
A review of nine adenocarcinomas of the esophagus arising in Barrett's epithelium was undertaken.
We found the disease among white males disproportionately.
Risk factors and incidence rate remain to be clarified.
Only one patient was in a surveillance program and only ... | C16 |
5,822 | 91 | Biology and clinical significance of cytogenetic abnormalities in childhood acute lymphoblastic leukemia.
Virtually all cases of childhood ALL have chromosomal abnormalities and half contain translocations, which are nearly equally divided between random and nonrandom rearrangements.
Nonrandom chromosomal abnormaliti... | C16 |
5,823 | 7,076 | Maternal genomic neutrophil FcRIII deficiency leading to neonatal isoimmune neutropenia.
The healthy mother of a child with transient immune neutropenia was found to be "NA-null." The mother's neutrophils did not react with anti-NA1 and anti-NA2 antibodies (polyclonal human alloantibodies and mouse monoclonal antibodi... | C16 |
5,824 | 54 | Aberrant origin of the right coronary artery as a potential cause of sudden death: successful anatomical correction.
A man with an aberrant right coronary artery and haemodynamically important prolapse of the mitral valve was successfully resuscitated.
The aberrant right coronary artery was thought to be a possible c... | C16 |
5,825 | 7,742 | Aortic atresia: survival to adulthood without surgery.
Aortic atresia is a rare congenital cardiac defect.
It usually leads to death in the neonatal period.
A patient with aortic atresia has survived to the age of 24 years without any surgical procedure.
In view of the uncertain results of reconstructive surgery th... | C16 |
5,826 | 3,250 | Randomized comparison of routine vs highly selective use of Doppler ultrasound and biophysical scoring to investigate high risk pregnancies
OBJECTIVE--To compare routine versus highly selective use of Doppler ultrasound and biophysical scoring in higher risk pregnancy.
DESIGN--A pragmatic randomized trial.
SETTING-... | C16 |
5,827 | 8,662 | Air leaks and vasopressin release.
Eleven very low birthweight babies being ventilated for respiratory problems during the first week of life developed air leaks on 22 occasions.
On 16 out of 19 occasions the infants showed increases in urinary excretion of vasopressin after these events and on 10 occasions out of 13... | C16 |
5,828 | 7,113 | Choroid plexus cysts and chromosomal defects
During a 4-year period, 83 pregnant women with fetal choroid plexus cysts were investigated in our unit.
Abnormal karyotypes were found in 20 fetuses, including trisomy 18 (n = 16), trisomy 13 (n = 1), triploidy (n = 1) and translocation Down's syndrome (n = 2).
All fetu... | C16 |
5,829 | 8,962 | Pregnancy outcome after inadvertent ivermectin treatment during community-based distribution.
Ivermectin is the drug of choice for community-based treatment of onchocerciasis.
Since pregnancy testing during mass distribution campaigns is not feasible, the safety of ivermectin in pregnancy must be established.
During... | C16 |
5,830 | 8,176 | Epitope mapping of human thyroglobulin. Heterogeneous recognition by thyroid pathologic sera.
Thyroglobulin is the major Ag of the thyroid gland involved in autoimmune pathologies.
Epitope mapping was carried out with a rabbit polyclonal immune serum against fusion proteins expressed in prokaryotic cells.
After scre... | C19 |
5,831 | 3,839 | Intercellular propagation of individually programmed growth bursts in FRTL-5 cells. Implications for interpreting growth factor actions.
Five methods are commonly used to quantify FRTL-5 cells' and other thyrocytes' growth in vitro and the impact of growth inhibiting or stimulating maneuvers: Total cell count, mitotic... | C19 |
5,832 | 4,271 | Adrenal medullitis in type I diabetes.
To investigate whether cell-mediated immunity against the adrenal medulla occurs in type I diabetes (IDDM), we conducted a retrospective autopsy study of adrenal glands from IDDM and nondiabetic subjects using formalin-fixed tissue.
Forty-four IDDM subjects, aged 4-67 yrs (mean ... | C19 |
5,833 | 5,712 | Aberrant splicing of androgen receptor mRNA results in synthesis of a nonfunctional receptor protein in a patient with androgen insensitivity.
Androgen insensitivity is a disorder in which the correct androgen response in an androgen target cell is impaired.
The clinical symptoms of this X chromosome-linked syndrome ... | C19 |
5,834 | 4,830 | Magnetic resonance imaging contrast agents: theory and application to the central nervous system.
The theoretical aspects of magnetic resonance (MR) imaging contrast agents are reviewed, and their current applications to the central nervous system (CNS) and their future applications are discussed.
Profound difference... | C19 |
5,835 | 9,862 | Parasympathetic nervous system activity in hypothyroidism determined by R-R interval variations on electrocardiogram.
Little is known about the relationship between hypothyroidism and the parasympathetic nervous system.
R-R interval variations revealed by electrocardiogram (ECG) are known to be a useful clinical indi... | C19 |
5,836 | 8,444 | Advanced protein glycosylation induces transendothelial human monocyte chemotaxis and secretion of platelet-derived growth factor: role in vascular disease of diabetes and aging.
Diabetes and aging are commonly accompanied by arterio- and atherosclerosis.
Infiltration of the arterial subendothelial intima by macropha... | C19 |
5,837 | 6,079 | Severe primary hyperparathyroidism in a neonate having a parent with hypercalcemia: treatment by total parathyroidectomy and simultaneous heterotopic autotransplantation.
Neonatal primary hyperparathyroidism is a life-threatening disease because of marked hypercalcemia and severe respiratory distress caused by the hyp... | C19 |
5,838 | 9,875 | Bartter's syndrome and diabetes mellitus.
We here report a case of Bartter's syndrome occurring in association with diabetes mellitus.
The patient, an insulin-dependent diabetic, presented with hypokalaemia, inappropriate kaliuresis and metabolic alkalosis.
He had high plasma renin activity, relatively low plasma al... | C19 |
5,839 | 463 | Lack of effect of clonidine and pentoxifylline in short-term therapy of diabetic peripheral neuropathy.
The goal of this study was to confirm or rule out anecdotal reports of beneficial effects of clonidine and pentoxifylline in the treatment of painful diabetic peripheral neuropathy.
Clonidine was administered to 16... | C19 |
5,840 | 4,257 | Low prevalence of thyrotropin receptor antibody in primary hypothyroidism in Japan.
The prevalence of TSH receptor antibody (TRAb), measured by RRA assay (TSH-binding inhibitor immunoglobulin, TBII) and biological stimulation-blocking assay (thyroid-stimulation blocking antibody, TSBAb), was examined in 134 consecutiv... | C19 |
5,841 | 5,690 | Treating diabetes in the elderly. What are the special considerations?
Management of diabetes in elderly patients generally follows the same lines as in younger patients; that is, improvement of blood glucose status with diet, oral hypoglycemic, and insulin therapy as required.
Older patients are more fragile, howeve... | C19 |
5,842 | 4,526 | Risk factors for gallstones among Chinese in Taiwan. A community sonographic survey.
A health survey of adults aged 30 years or more was carried out in southwest Taiwan to determine the prevalence of gallstones and to study risk factors associated with gallstones.
Blood samples were collected and abdominal sonographi... | C19 |
5,843 | 4,225 | Defective fasciculata zone function as the mechanism of glucocorticoid-remediable aldosteronism.
Glucocorticoid-remediable aldosteronism is characterized by unusual sensitivity of aldosterone secretion to ACTH.
Suppressibility by glucocorticoid and continued stimulability by exogenous ACTH has provided the basis for ... | C19 |
5,844 | 3,933 | Short-term administration of captopril and nifedipine and exercise-induced albuminuria in normotensive diabetic patients with early-stage nephropathy.
Recent studies have demonstrated that short-term angiotensin converting enzyme (ACE) inhibition with captopril can reduce urinary albumin excretion rate (UAER) after ex... | C19 |
5,845 | 8,633 | Final height in boys with untreated constitutional delay in growth and puberty.
To determine the natural history and psychological impact of the growth pattern in boys with constitutional delay in growth and puberty (CDGP), 43 boys presenting with short stature due to CDGP were followed up to final height.
At present... | C19 |
5,846 | 3,980 | Multiple hormone elevations in Zollinger-Ellison syndrome. Prospective study of clinical significance and of the development of a second symptomatic pancreatic endocrine tumor syndrome.
In the present study of 45 patients with Zollinger-Ellison syndrome, the frequency and clinical importance of the release of multiple... | C19 |
5,847 | 3,932 | Marked improvement of glucose homeostasis in diabetic ob/ob mice given oral vanadate.
The trace element vanadium exerts insulinlike effects in vitro and decreases hyperglycemia in insulin-deficient animals.
This study examined whether vanadate can improve glucose homeostasis in genetically obese hyperglycemic insulin... | C19 |
5,848 | 9,879 | Reliability of death certificate diagnoses.
Consistency between death certificates and clinical records from 5 general hospitals in Kuwait was studied for 470 deaths with the following underlying or associated causes: hypertensive (HYP), ischaemic heart diseases (IHD), cerebrovascular diseases (CVD) and diabetes melli... | C19 |
5,849 | 5,481 | Radiation necrosis of the optic chiasm, optic tract, hypothalamus, and upper pons after radiotherapy for pituitary adenoma, detected by gadolinium-enhanced, T1-weighted magnetic resonance imaging: case report.
A 26-year-old woman was treated for a prolactin secreting pituitary adenoma by surgery and radiotherapy (5860... | C19 |
5,850 | 8,478 | The role of adrenalectomy in Cushing's syndrome.
Forty-four patients with Cushing's syndrome were treated by adrenalectomy between 1975 and 1989.
Twenty patients had adrenal adenomas: 13 with obvious Cushing's syndrome and 7 whose disease was subclinical, detected after evaluation of an incidentally discovered adrena... | C19 |
5,851 | 2,974 | Morbidity, mortality, and quality of life for patients treated with levothyroxine
In a population study of 1462 middle-aged women initiated in 1968 and 1969 we identified 29 women treated with levothyroxine from 1 to 28 years.
In a 12-year follow-up in 1980 and 1981 we investigated the subjects for end-point myocard... | C19 |
5,852 | 5,887 | Adrenal dysfunction in patients with renal amyloid.
Amyloidosis is a multi-system disease.
Renal involvement often leads to end-stage renal failure, which carries a poor prognosis.
This paper reports the adrenal status of 22 patients with renal amyloid who were considered for or who had been commenced on renal repla... | C19 |
5,853 | 4,228 | Insulin-like growth factor-I receptors in nonfunctioning thyroid nodules.
We have recently demonstrated the production of insulin-like growth factor-I (IGF-I) as well as the presence of type I IGF receptors in human thyroid cells in primary culture.
The role of IGF-I in the control of thyroid cell growth has been wel... | C19 |
5,854 | 343 | Management of primary hypothyroidism.
Primary hypothyroidism is a common condition requiring lifelong treatment and monitoring.
The type and amount of thyroid hormone replacement, selection of laboratory tests, and timing of office visits are all important for optimizing patient well-being and reducing the costs of m... | C19 |
5,855 | 5,243 | Parathyroid hormone-related peptide in plasma of patients with hypercalcemia and malignant lesions
We developed and validated a radioimmunoassay for circulating human parathyroid hormone-related peptide (PTHrP), based on a commercial antiserum to the synthetic 1-34 fragment of PTHrP, 125I-Tyr degrees-PTHrP(1-34) as r... | C19 |
5,856 | 8,341 | A human XY female with a frame shift mutation in the candidate testis-determining gene SRY.
The primary decision about male or female sexual development of the human embryo depends on the presence of the Y chromosome, more specifically on a gene on the Y chromosome encoding a testis-determining factor, TDF.
The human... | C19 |
5,857 | 9,626 | Preoperative cytology and mammography in patients with single-duct nipple discharge treated by surgery.
Microdochectomy has been the routine management for single-duct nipple discharge.
Our review of 176 consecutive patients surgically treated between 1975 and 1988 revealed eight patients with in situ carcinomas and ... | C19 |
5,858 | 4,728 | Screening diabetic patients for microalbuminuria.
Abnormal rates of urinary albumin excretion have been shown to predict the development of nephropathy and may signal atherosclerotic disease in diabetic patients.
This study demonstrated the feasibility of measuring microalbuminuria in diabetic patients from a large f... | C19 |
5,859 | 2,183 | Risk factors for white matter changes detected by magnetic resonance imaging in the elderly.
We found increased age (p = 0.001) and history or evidence of stroke (p = 0.016) to be significant independent multivariate predictors of the presence and severity of leukoencephalopathy on magnetic resonance imaging brain sca... | C19 |
5,860 | 6,227 | Subgroups of patients with atypical circadian patterns of symptom onset in acute myocardial infarction.
Circadian variation of onset of acute myocardial infarction has been noted in many studies and may carry important implications.
However, only a few previous studies have attempted subgroup analysis.
In 4,796 pati... | C19 |
5,861 | 6,776 | Cardiovascular effects of the somatostatin analog octreotide in acromegaly.
OBJECTIVE: To determine the cardiovascular effects of the somatostatin analog octreotide in patients with acromegaly.
DESIGN: Prospective nonrandomized study.
SETTING: Referral-based endocrinology clinic.
PATIENTS: Seven patients with activ... | C19 |
5,862 | 4,223 | Susceptibility to thyroid autoimmune disease: molecular analysis of HLA-D region genes identifies new markers for goitrous Hashimoto's thyroiditis.
Hashimoto's thyroiditis has been shown to be associated with the HLA-specificities DR4 and DR5.
Since former association studies yielded variable results, we used novel m... | C19 |
5,863 | 9,832 | Sudden death associated with undiagnosed Graves' disease.
Hyperthyroidism may result in multiple symptoms attributable to an excess of thyroid hormone.
We report a case of Graves' disease in association with sudden death in a previously healthy, undiagnosed young female.
This case illustrates an unusual initial pres... | C19 |
5,864 | 7,231 | Adverse mortality experience of a southwestern American Indian community: overall death rates and underlying causes of death in Pima Indians.
As part of an ongoing epidemiologic study, the death rate and causes of death during 1975 through 1984 were determined in Pima Indians who resided in the Gila River Indian Commu... | C19 |
5,865 | 2,620 | Thyroid function and ultrasonically determined thyroid size in patients receiving long-term lithium treatment.
Thyroid function was investigated in 100 manic-depressive patients.
Goiter was more common in patients treated with lithium for 1-5 years (44%) or more than 10 years (50%) than in patients who never received... | C19 |
5,866 | 4,388 | Prolonged anginal perceptual threshold in diabetes: effects on exercise capacity and myocardial ischemia.
Anginal perceptual threshold (the time from onset of 0.1 mV of ST segment depression to onset of angina during treadmill exercise) is prolonged in diabetic patients with coronary artery disease.
In the present st... | C19 |
5,867 | 2,432 | Liver pathology in morbidly obese patients with and without diabetes.
The contribution of obesity and/or diabetes to liver pathology in the morbidly obese patient is controversial.
We studied the liver biopsies of 100 consecutive patients undergoing gastric bypass surgery for morbid obesity.
Multiple morphologic par... | C19 |
5,868 | 3,961 | Metabolic effects of 1200-kcal diet in obese pregnant women with gestational diabetes.
Calorie restriction is widely used as a primary therapy for obese pregnant women with gestational diabetes.
To better understand the metabolic consequences of marked calorie restriction, we performed a randomized prospective trial ... | C19 |
5,869 | 6,360 | Does magnesium play a role in the hypokalemia of Bartter's syndrome?
A patient with Bartter's syndrome manifested hypomagnesemia in addition to hypokalemia.
Under conditions of maximal free water production, he had a fractional distal solute reabsorption of 0.65, a value consistent with a renal defect in sodium chlor... | C19 |
5,870 | 2,117 | Surgical management of islet cell dysmaturation syndrome in young children.
Islet cell dysmaturation syndrome (ICDS) encompasses the causes of infantile hyperinsulinemic hypoglycemia histologically described as islet cell hyperplasia, pancreatic adenomatosis and nesidioblastosis.
Eleven infants underwent 14 pancreati... | C19 |
5,871 | 3,303 | Unawareness of hypoglycaemia and inadequate hypoglycaemic counterregulation: no causal relation with diabetic autonomic neuropathy
OBJECTIVE--To examine the traditional view that unawareness of hypoglycaemia and inadequate hypoglycaemic counterregulation in insulin dependent diabetes mellitus are manifestations of au... | C19 |
5,872 | 3,622 | Total knee arthroplasty in diabetes mellitus.
A retrospective study was done of 59 total knee arthroplasties (TKAs) in 40 patients diagnosed with diabetes mellitus.
The overall infection rate was 7%, with an overall revision rate of 10% and an average follow-up period of 4.3 years.
Wound complications were present i... | C19 |
5,873 | 8,480 | Cytoreductive hepatic surgery for neuroendocrine tumors.
We retrospectively reviewed 37 patients who underwent hepatic resection between 1970 and 1989 to evaluate the role of cytoreductive hepatic surgery in patients with metastatic neuroendocrine tumors (carcinoid, 24; islet cell, 13).
Seventeen resections were cura... | C19 |
5,874 | 8,473 | Evaluation of metastatic cardiac calcification in a model of chronic primary hyperparathyroidism.
Recent reports have fueled an interest in the prevalence and significance of metastatic calcium deposition in patients with chronic hyperparathyroidism.
Experimental data are limited by the lack of suitable in vivo anima... | C19 |
5,875 | 8,913 | Hyperinsulinemia increases the amount of GLUT4 mRNA in white adipose tissue and decreases that of muscles: a clue for increased fat depot and insulin resistance.
To mimick a state of hyperinsulinemia, normal rats were infused with insulin for 4 days via minipumps, and compared to saline infused rats.
At the end of th... | C19 |
5,876 | 2,328 | Circadian rhythmicity of rate-normalized QT interval in hypothyroidism and its significance for development of class III antiarrhythmic agents.
Lengthening of repolarization and refractoriness occurs in hypothyroidism; it is associated with a reduced probability of arrhythmias, with the converse occurring in hyperthyr... | C19 |
5,877 | 4,274 | Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects.
Although minimal model analysis of frequently sampled iv glucose tolerance tests (FSIGTs) to measure insulin sensitivity is well recognized, application has been limited by the need for endogenous insulin sec... | C19 |
5,878 | 2,640 | Initial failure of surgical exploration in patients with primary hyperparathyroidism.
To determine the causes of failures of cervical exploration for primary hyperparathyroidism, we reviewed 892 patients operated on by one surgeon from 1953 to 1990.
Twenty-seven patients (3%) remained hypercalcemic or developed hyper... | C19 |
5,879 | 6,932 | Thyrotoxicosis induced by topical iodine application.
We describe an elderly man who was admitted with congestive cardiac failure and found to have thyrotoxicosis.
He did not have goiter, and he had normal radioiodine uptake in his neck.
Serum iodine levels were elevated, explaining the lack of increase in radioiodi... | C19 |
5,880 | 222 | Sex hormone receptors in human thyroid tissues.
The behavior of sex hormone receptors was studied in the cytosol of thyroid tissue samples in order to clarify the effects of sex hormones on diseases of the thyroid.
Androgen receptor (AR), estrogen receptor (ER), and progesterone receptor (PgR) were assayed using the ... | C19 |
5,881 | 3,005 | Solid and cystic ultimobranchial body remnants in the thyroid.
In this study we determined the incidence rate (89%) and characterized the morphology of ultimobranchial body (UBB) remnants found in 18 serially sectioned neonatal thyroid glands.
Although UBB remnants are often referred to as solid cell nests, we found ... | C19 |
5,882 | 2,323 | Patient-related variables and restenosis after percutaneous transluminal coronary angioplasty--a report from the M-HEART Group.
As part of a randomized prospective study designed to investigate the restenosis process after percutaneous transluminal coronary angioplasty (PTCA), the relation between patient-related vari... | C19 |
5,883 | 2,420 | Thymic hyperplasia. A clue to the diagnosis of hyperthyroidism.
The association of simultaneous abnormalities of the thyroid and thymus is well documented, particularly in the case of Graves' disease.
We present a case of a natural death following thyroid storm in which marked thymic hyperplasia was present.
This fi... | C19 |
5,884 | 3,032 | The operative management of coexisting thyroid and parathyroid disease.
Three hundred eight patients who underwent operation for hyperparathyroidism were studied.
Fifty-two (17%) were identified who had a concomitant thyroid nodule.
All 52 underwent parathyroidectomy and thyroid resection in a single operation.
Ele... | C19 |
5,885 | 7,976 | Nephropathy in model combining genetic hypertension with experimental diabetes. Enalapril versus hydralazine and metoprolol therapy.
We compared the effects of the angiotensin-converting enzyme inhibitor enalapril and a conventional antihypertensive regimen (hydralazine and metoprolol) on kidney function, albuminuria,... | C19 |
5,886 | 8,339 | Genetic evidence equating SRY and the testis-determining factor.
The testis-determining factor gene (TDF) lies on the Y chromosome and is responsible for initiating male sex determination.
SRY is a gene located in the sex-determining region of the human and mouse Y chromosomes and has many of the properties expected ... | C19 |
5,887 | 2,641 | Results of surgical treatment for hyperparathyroidism associated with renal disease.
Recently, the role and timing of surgery for treating secondary and tertiary hyperparathyroidism (HPT) have been questioned.
In order to delineate the indications for surgery in these patients, a retrospective analysis of 53 consecut... | C19 |
5,888 | 547 | Increased transcapillary escape rate of albumin in nondiabetic men in response to hyperinsulinemia.
Diabetic patients manifest increased vascular permeability.
To determine whether insulin per se might increase vascular permeability, five nondiabetic men were studied by the hyperinsulinemic-euglycemic clamp technique... | C19 |
5,889 | 6,320 | Disproportionate septal hypertrophy associated with erythroblastosis fetalis.
We retrospectively reviewed clinical and echocardiographic data on 10 newborns with erythroblastosis fetalis who were admitted to our nurseries between 1984 and 1988 and who required a double-volume exchange transfusion and neonatal intensiv... | C19 |
5,890 | 3,951 | Metabolic effects of hyperglycemia and hyperinsulinemia on fate of intracellular glucose in NIDDM.
Hyperglycemia in non-insulin-dependent diabetes mellitus (NIDDM) stimulates peripheral glucose uptake, which tends to compensate for impaired insulin-mediated glucose uptake.
The metabolic fate of glucose and suppressio... | C19 |
5,891 | 3,271 | Lobular pattern of choriocapillaris in pre-eclampsia with aldosteronism.
We report a case of geographic or mosaic pattern yellowish opaque foci in the left eye of a 36-year-old woman who suffered from severe pre-eclampsia.
Though the geographic lesions resulted in chorioretinal atrophy, the mosaic lesion led to no si... | C19 |
5,892 | 4,777 | Resistance to ischaemia of small afferent nerve fibres in diabetes mellitus.
Thermal thresholds were measured in the left forearms of 26 healthy subjects and 10 patients with diabetes mellitus during ischaemic compression block.
During the period when ischaemic block of large fibres caused paraesthesia and loss of to... | C19 |
5,893 | 2,474 | Diabetes mellitus and hypertension.
Hypertension and diabetes mellitus are chronic medical conditions that frequently coexist.
In the United States, it is estimated that 10 million persons suffer from diabetes mellitus, 60 million from hypertension, and 3 million from the combination of the two.
There may be a causa... | C19 |
5,894 | 3,738 | Hypothyroidism and pleural effusions.
Serous effusions have been thought to be an unusual complication of hypothyroidism and most commonly have been associated with ascites, pericardial fluid and heart failure.
Pleural fluid as an isolated finding in hypothyroidism is apparently rare and complete analysis of these hy... | C19 |
5,895 | 2,451 | Hyperkalemia in the elderly.
Physiologic and pathologic events that occur in patients as they grow older may result in distal renal tubular dysfunction, as well as decreased levels of plasma renin activity and plasma aldosterone.
Such alterations result in a tendency toward hyperkalemia.
A syndrome termed hyporenine... | C19 |
5,896 | 5,482 | Pituitary hemorrhage into a Rathke's cleft cyst
This report describes a case of symptomatic pituitary hemorrhage into a Rathke's cleft cyst in a 25-year-old woman.
The literature on pituitary hemorrhage in nonadenomatous sellar tumors is reviewed. | C19 |
5,897 | 6,356 | Ultrasonography in the differentiation of complicated and uncomplicated acute pyelonephritis.
Differentiation of uncomplicated pyelonephritis versus complicated pyelonephritis has always been problematic.
No clear physical signs or symptoms are diagnostic.
To study differences between the two, we retrospectively rev... | C19 |
5,898 | 3,350 | Aetiology of pancreatic cancer
Curative surgery is possible in only a small minority of patients with pancreatic cancer and, to date, responses to chemotherapy and radiotherapy have been disappointing.
To make any impact on the incidence of the disease a clearer understanding of its aetiology is required.
This revi... | C19 |
5,899 | 2,579 | Magnetic resonance imaging of radiation optic neuropathy.
Three patients with delayed radiation optic neuropathy after radiation therapy for parasellar neoplasms underwent magnetic resonance imaging.
The affected optic nerves and chiasms showed enlargement and focal gadopentetate dimeglumine enhancement.
The magneti... | C19 |
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