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Parathyroid autotransplantation This paper reviews the technique, indications and results of parathyroid autotransplantation. Autotransplantation is most commonly indicated following parathyroidectomy for renal osteodystrophy, but can also be used in primary hyperplastic hyperparathyroidism, re-exploration of the ne...
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5,901
2,512
Effect of dietary protein restriction on functional renal reserve in diabetic nephropathy. PURPOSE, PATIENTS, AND METHODS: Functional renal reserve in patients with insulin-dependent diabetes mellitus, as determined by the glomerular filtration rate (GFR) response test, is a measure of the capacity of the kidney to in...
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5,902
8,551
Pericardial effusion in primary hypothyroidism. Pericardial effusion is reported to occur in 30% to 80% of subjects with hypothyroidism. However, these earlier studies were conducted when the diagnosis of hypothyroidism was only suspected and was confirmed only in the presence of classic clinical features. In contra...
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5,903
2,112
Total parathyroidectomy and autotransplantation in hyperplasia of the parathyroid gland. Hyperparathyroidism caused by multiple-gland hyperplasia has traditionally been treated by subtotal parathyroidectomy. Excellent results have been reported by some, particularly in primary hyperparathyroidism, but other have repo...
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5,904
5,104
Isolated primary aldosteronism in a patient with adrenal carcinoma and XY/XXY mosaic Klinefelter's syndrome. Although breast cancer, germ cell tumors and other neoplasms are known to occur in patients with Klinefelter's syndrome, adrenal carcinoma has not yet been reported in such patients. We describe a rare case of...
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5,905
464
Measuring vibration sensations with graduated tuning fork. Simple and reliable means to detect diabetic patients at risk of neuropathic foot ulceration. To find a simple and reliable means to measure vibration sensations, 189 diabetic patients and 88 control subjects were tested at different sites with a graduated tun...
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5,906
9,549
In vitro and in vivo testing of an electrocatalytic glucose sensor. A prerequisite for the development of an implantable artificial pancreas is the availability of a stable, long-life glucose sensor. Platinum (Pt) catalyzed electrodes have been demonstrated in vitro to show high sensitivity to glucose and long cycle ...
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5,907
8,635
Hyperinsulinaemic hypoglycaemia in small for dates babies. Blood glucose concentrations were measured prospectively in 27 small for dates infants in the first 48 hours after birth: 10 infants became hypoglycaemic. Of these, five had inappropriately raised plasma insulin concentrations. Plasma free fatty acids were l...
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5,908
8,483
The utility of circulating levels of human pancreatic polypeptide as a marker for islet cell tumors. The measurement of plasma levels of human pancreatic polypeptide (hPP) has been reported to be clinically useful in predicting the existence of pancreatic islet cell neoplasms in patients with familial multiple endocri...
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5,909
3,938
Anti-islet cell antibodies from NOD mice. We produced a panel of monoclonal autoantibodies from the spleen cells of prediabetic nonobese diabetic mice. The antibodies were selected on the basis of their ability to bind to the surface of nondiabetic mouse islet cells, and from greater than 4000 hybridomas screened, 35...
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5,910
8,474
Cardiac calcific deposits in patients with primary hyperparathyroidism: preliminary results of a prospective echocardiographic study. To explain the incidence and significance of mitral and aortic valve calcification and calcific deposits in the myocardium, a prospective echocardiographic study was performed with 21 c...
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5,911
3,944
Insulin and hypertension. Relationship to obesity and glucose intolerance in Pima Indians. The relationships among blood pressure, obesity, glucose tolerance, and serum insulin concentration were studied in 2873 Pima Indians aged 18-92 yr (mean 37 yr). Age- and sex-adjusted to the Pima population, the prevalence of h...
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5,912
4,245
Primary hyperparathyroidism and severe hypercalcemia with low circulating 1,25-dihydroxyvitamin D. We report a postmenopausal woman with primary hyperparathyroidism (PHPT) and severe hypercalcemia while her total calcium intake was more than 2 g daily. Despite a markedly elevated intact PTH level, her serum 1,25-dihy...
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5,913
8,475
Hyperparathyroidism and cellular mechanisms of gastric acid secretion. Patients with hyperparathyroidism appear to be a particular risk for peptic ulcer disease. To test the hypothesis that hypercalcemia or parathyroid hormone plays a role in promoting ulcer disease, we studied the effect of varying concentrations of...
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5,914
6,013
Cytophagic histiocytic panniculitis evolving into total lipodystrophy. A 15-year-old boy had persistent fever with severe neutropenia, thrombocytopenia, coagulation disorder, and marked elevation of lactate dehydrogenase values. A diagnosis of cytophagic histiocytic panniculitis was made after repeated skin biopsies....
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5,915
4,268
Effect of chronic treatment with the glucocorticoid antagonist RU 486 in man: toxicity, immunological, and hormonal aspects. Suppression of immune function was traditionally thought to occur only with pharmacological levels of glucocorticoids. However, recent studies in rodents have suggested that glucocorticoids exe...
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5,916
5,352
Central changes in hypothyroid myopathy: a case report. A muscle biopsy from a patient with hypothyroid myopathy showed striking central changes. "Cores" were seen in most type 1 fibers with oxidative enzyme preparations. Electron microscopy of these areas revealed Z disc streaming, myofilament disruption, and absen...
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5,917
8,468
Multiple parathyroid adenomas: report of thirty-three cases. An increasing number of patients with primary hyperparathyroidism are found to have two or three enlarged parathyroid glands. Of 865 patients successfully operated on by one surgeon (J.N.A.), multiple enlarged parathyroid glands (adenomas) were found and re...
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5,918
8,469
Endosonography in the localization of parathyroid tumors: a preliminary study. A preoperative transesophageal exploration of the parathyroids by endosonography was performed on 23 patients with primary hyperparathyroidism. The system used was a 7.5 MHz transducer mounted on the tip of an endoscope with an external di...
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5,919
5,431
Thickness of carotid artery atherosclerotic plaque and ischemic risk. Noninvasive duplex scanning of carotid artery atherosclerotic plaque was performed in 286 consecutive patients referred to a cerebrovascular diagnostic laboratory. The presence and thickness of such plaque in the region of the carotid bifurcation w...
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5,920
3,299
Sodium-lithium countertransport activity in red cells of patients with insulin dependent diabetes and nephropathy and their parents OBJECTIVE--To determine whether there are familial and genetic aspects of sodium-lithium countertransport activity in red cells in diabetic nephropathy. DESIGN--Case-control study. SET...
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5,921
3,161
Parathyroid hormone and the vascular response to norepinephrine. Norepinephrine blood pressure reactivity is reduced in uremia, an effect attributed to excess parathyroid hormone (PTH). Most, but not all, animal and human studies support the theory that high PTH levels diminish the pressor response to norepinephrine....
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5,922
4,293
Thyroiditis as the presenting manifestation of disseminated extrapulmonary Pneumocystis carinii infection. A 38-yr-old male with acquired immunodeficiency syndrome developed neck pain in association with mild hyperthyroidism and a diffusely enlarged thyroid gland. Radioactive iodine scanning was consistent with thyro...
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5,923
2,853
Relation of hyperglycemia early in ischemic brain infarction to cerebral anatomy, metabolism, and clinical outcome. We studied the relation of serum glucose level measured in the first 12 hours of symptoms to the clinical findings, results of computed tomography (CT), and patterns of cerebral metabolism in 39 patients...
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5,924
7,839
Simplified two-stage below-knee amputation for unsalvageable diabetic foot infections. A simplified two-stage below-knee amputation for unsalvageable diabetic foot infections was done on 19 limbs with 84% good results for healing. The first stage was the standard below-knee amputation with a long posterior flap in wh...
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5,925
9,649
Thallous chloride uptake and DNA profile in parathyroid adenomas. Thallium isotope scintigraphy is used to localize parathyroid adenomas but the mechanism underlying the technique is poorly understood. While larger adenomas are reliably localized the results are less certain for small tumours. This study explores th...
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5,926
6,737
Ponderal index as a predictor of postoperative complications. Four hundred sixty-eight patients undergoing elective surgery were prospectively followed for the development of postoperative complications. There was a trend toward increasing complication rate with a lower ponderal index. However, lower ponderal indice...
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5,927
2,976
Lipoprotein and apolipoprotein levels in subclinical hypothyroidism. Effect of levothyroxine therapy. To assess whether subclinical hypothyroidism is associated with changes in lipoprotein fractions, 13 patients maintained in a stable state of subclinical hypothyroidism for at least 3 months were studied prior to and ...
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5,928
2,816
Urgent management of a giant scrotal hernia. An unusual case of giant scrotal hernia is presented. Hernias of this magnitude are extremely rare, even in underdeveloped countries, and their repair is challenging to the surgeon and stressful to the patient. Only a few case reports on the use of pneumoperitoneum prior ...
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5,929
3,342
Through-knee amputation in high-risk patients with vascular disease: indications, complications and rehabilitation. During a 10-year period 104 patients (mean age 72 years) had 106 through-knee amputations. Indications for surgery were: limb gangrene, 67 (64 per cent); ischaemic ulceration, 22 (21 per cent); rest pai...
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5,930
8,671
Surgical strategy in thyroid disease. Over the past 8 years, 311 patients have undergone surgical treatment by the senior authors for thyroid disease. Over 80% of the cases were performed by the head and neck surgical service at Olive View County Hospital, Sylmar, Calif, with the remainder performed at UCLA-affiliate...
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5,931
6,284
Iodine and selenium deficiency associated with cretinism in northern Zaire. Selenium status was determined in an endemic-goiter area and in a control area of Zaire. Compared with the reference values of a noniodine-deficient area, serum selenium in subjects living in the core of the northern Zaire endemic-goiter belt...
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5,932
3,946
Structural abnormality in LDL from diabetic patients as revealed by resonance Raman spectroscopy. Resonance Raman spectra of low-density lipoprotein (LDL) isolated from the plasma of diabetic patients (age range 13-77 yr, mean age 37 yr) and age- and sex-matched control subjects were recorded in the 1000- to 1600-cm-1...
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5,933
800
Mutation of the signal peptide-encoding region of the preproparathyroid hormone gene in familial isolated hypoparathyroidism. Preproparathyroid hormone (preproPTH) gene mutation has been proposed as a cause of familial isolated hypoparathyroidism (FIH). We cloned the preproPTH alleles of a patient with autosomal domi...
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5,934
4,292
Gastrointestinal side-effects of octreotide during long-term treatment of acromegaly. Gastrointestinal side-effects of prolonged therapy (greater than 2 yr) with the long-acting somatostatin analog octreotide were studied in 10 acromegalic patients. After 2 yr of therapy, 6 of 10 patients had newly developed gallston...
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5,935
492
Fertility after contraception or abortion. There is a very small correlation, if any, between the prior use of OCs and congenital malformations, including Down's syndrome. There are few, if any, recent reports on masculinization of a female fetus born to a mother who took an OC containing 1 mg of a progestogen during...
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5,936
4,218
Substance-P is present in a subset of thyrotrophs in the human pituitary. Substance-P immunoreactivity and tachykinin-like peptides are present in the pituitary gland of several mammalian species. In humans, however, the biochemical nature and cellular localization of pituitary substance-P has not been defined. We r...
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5,937
2,454
Geriatric diabetic nephropathy: an analysis of renal referral in patients age 60 or older. We report a series of 33 consecutive hospitalized geriatric diabetic patients who were referred for evaluation of diabetic nephropathy, defined as proteinuria greater than or equal to 1 g/d (1,000 mg/24 h) or a serum creatinine ...
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5,938
239
Klinefelter's syndrome with anomalous origin of left main coronary artery Klinefelter's syndrome is a rare entity. Even rarer is an anomalous origin of the Left Main Coronary Artery. For both conditions to occur in the same patient is hence exceedingly rare. Reported here is a never previously reported case of a c...
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5,939
4,287
Effects of repetitive administration of corticotropin-releasing hormone combined with lysine vasopressin on plasma adrenocorticotropin and cortisol levels in secondary adrenocortical insufficiency. To examine the functioning of the hypothalamo-pituitary-adrenocortical axis in secondary adrenocortical insufficiency, we...
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5,940
5,877
Antidiabetic agents. Although either insulin or oral hypoglycemics may be used in conjunction with diet and exercise in the management of type II diabetes, drug therapy for type I diabetes involves only insulin. C-peptide levels can be tested to assess whether the patient has remaining pancreatic endocrine function. ...
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5,941
8,381
The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms. The effect of the selective serotonin reuptake inhibitor paroxetine on diabetic neuropathy symptoms was examined in comparison to imipramine and placebo in a randomised, double-blind, cross-over study. ...
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5,942
9,889
An inconsistent relationship between insulin and blood pressure in three Pacific island populations. The evidence linking insulin to blood pressure is controversial, and results for groups similarly categorized by body mass, glucose tolerance and hypertensive status are often contradictory. We have investigated the r...
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5,943
7,516
Gallstones, cholecystitis and diabetes [published erratum appears in Surg Gynecol Obstet 1991 Jul;173(1):72] Findings from studies showing an increased incidence of gallstones in diabetic patients do not control for other variables, such as obesity. There is no proof that diabetic patients have more gallstones. Gall...
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5,944
6,924
Medical comorbidity of major depressive disorder in a primary medical practice. Despite much speculation about the relationship between depression and medical comorbidity in primary care settings, few investigators have examined this issue empirically. Using a two-stage screening procedure, we assessed 618 patients a...
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5,945
7,969
Influence of obesity, impaired glucose tolerance, and NIDDM on LDL structure and composition. Possible link between hyperinsulinemia and atherosclerosis. The possible causes of the enhanced risk for coronary heart disease (CHD) were examined in morbidly obese women with normoglycemia, impaired glucose tolerance (IGT),...
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5,946
2,486
Definitive localization of X-linked Kallman syndrome (hypogonadotropic hypogonadism and anosmia) to Xp22.3: close linkage to the hypervariable repeat sequence CRI-S232 [published erratum appears in Am J Hum Genet 1990 Nov;47(5):883] Kallmann syndrome is a genetically heterogeneous disease characterized by hypogonadotr...
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5,947
4,280
Parathyroid hormone and cirrhosis of the liver. Fifty patients with liver cirrhosis (36 alcoholic, 1 drug-induced, 7 posthepatitic, and 6 cryptogenic) and normal renal function were investigated to determine whether PTH levels in serum, measured using the common midregion human PTH-(44-68) RIA, are elevated in such pa...
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5,948
519
Secondary hypogonadism in hemochromatosis. Hemochromatosis is a rare disorder of iron storage. This report illustrates a case of hypogonadotropic-hypogonadism in a female with biopsy-proven hemochromatosis. Dynamic pituitary and gonadal testing revealed subnormal gonadotropin responses to gonadotropin-releasing horm...
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5,949
8,634
Short stature, mental retardation, and hypoparathyroidism: a new syndrome. Eight children (four boys and four girls) with extreme failure to thrive, dysmorphic features, developmental delay, hypoparathyroidism, and abnormal skeletal survey were studied. They were the products of seven consanguinous marriages, two of ...
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5,950
3,339
Mastalgia refractory to drug treatment. Management of the patient with mastalgia who fails to respond to first line therapy is a difficult problem and there is a group of patients who do not respond to any therapy. A group of 126 patients with mastalgia who failed to respond to first line therapy and completed furthe...
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5,951
3,763
Axillosubclavian vein thrombosis produced by retrosternal thyroid. Several causes of axillosubclavian vein thrombosis have been described. Trauma to the subclavian vein by pacemaker wires or central venous lines as well as the so-called effort thrombosis have been recognized as frequently diagnosed precipitating fact...
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5,952
9,871
Rebound increase in serum thyrotropin, anti-'microsomal' antibodies and thyroglobulin after discontinuation of L-thyroxine. We assayed serum thyrotropin (TSH), antimicrosomal antibodies (MSA), antithyroglobulin antibodies and thyroglobulin in seven individuals with subclinical autoimmune hypothyroidism during two 6-mo...
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5,953
2,162
Intraoperative parathormone level measurement in the management of hyperparathyroidism. To investigate the potential use of intraoperative intact parathormone measurements to predict curative parathyroidectomy, we measured ionized calcium (Cai) levels and parathormone levels in 33 patients with hyperparathyroidism who...
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5,954
6,385
Interrelationships between age, thyroid volume, thyroid nodularity, and thyroid function in patients with sporadic nontoxic goiter. PURPOSE: To test the hypothesis that during the natural history of sporadic nontoxic goiter (SNG), a diffuse goiter precedes a multinodular goiter with gradual development of autonomous t...
C19
5,955
4,230
Short term treatment of acromegaly with the somatostatin analog octreotide: the first double-blind randomized placebo-controlled study on its effects. Several studies suggest that the somatostatin analog octreotide, or SMS 201-995, may effectively reduce GH hypersecretion. However, no double blind, placebo-controlled...
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5,956
7,579
Unusual variants of adrenal pseudocysts with intracystic fat, myelolipomatous metaplasia, and metastatic carcinoma. Five previously unreported cases of adrenal pseudocysts are described that demonstrate a wider range of histologic appearances than has been previously recognized in these lesions. One pseudocyst remove...
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5,957
474
Total serum glycosylated proteins in detection and monitoring of gestational diabetes. The goal of this study was to determine whether serum glycosylated protein levels (i.e., fructosamine) can reliably screen for gestational diabetes and whether these levels are valid markers of short-term glycemic control in the thi...
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5,958
6,373
A new DNA marker (D10S94) very tightly linked to the multiple endocrine neoplasia type 2A (MEN2A) locus. Combined somatic cell hybrid and linkage studies between D10S94 and five pericentromeric loci (FNRB, D10Z1, MEN2A, RBP3, and D10S15) have localized the new DNA sequence pcl1/A1S-6-c23 at D10S94 to 10q11.2. No reco...
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5,959
3,055
X-linked spinal muscular atrophy (Kennedy's syndrome). A kindred with hypobetalipoproteinemia. Kennedy's syndrome, X-linked adult-onset bulbospinal muscular atrophy, has been described in over 30 families. The characteristic distribution of weakness creates a recognizable syndrome, augmented by frequent findings of t...
C19
5,960
8,467
Lithiumogenic disorders of the thyroid and parathyroid glands as surgical disease. Little notice has been paid in the surgical literature to problems with psychoeffective lithium, which by interfering with adenylate cyclase affects thyroid and parathyroid function, causing hypercalcemia, hyperparathyroidism, and hypot...
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5,961
4,963
Training obstetrics-and-gynecology residents to manage breast disease. Incorporation into a breast care clinic. The American Board of Obstetricians and Gynecologists recently issued a directive that education in breast disease be incorporated into all residency training programs. At the University of Michigan Medical...
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5,962
6,043
The predictive value of needle localization mammographically assisted biopsy of the breast. This study was done to review critically the experience at the University of California at San Diego in needle localization mammographic biopsy of the breast with regard to use and accuracy in identifying early carcinoma of the...
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5,963
4,484
A review of iodine toxicity reports. This article summarizes case reports, population studies, and experimental studies from the literature concerning adverse effects of exposure to iodine from the mid-1880s to 1988. Exposure to excessive iodine through foods, dietary supplements, topical medications, and/or iodinate...
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5,964
4,281
Tumor necrosis factor: a putative mediator of the sick euthyroid syndrome in man. Tumor necrosis factor-alpha (TNF) is believed to be an important mediator in many diseases that are associated with the sick euthyroid syndrome. To investigate the effect of TNF on thyroid hormone metabolism, we performed a controlled s...
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5,965
6,183
Silent myocardial ischemia and infarction in diabetics with peripheral vascular disease: assessment by dipyridamole thallium-201 scintigraphy. We investigated the incidence of silent myocardial ischemia and infarction as assessed by dipyridamole thallium scintigraphy in 30 diabetic patients with peripheral vascular di...
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5,966
527
Effect of hyperinsulinemia and hyperglycemia on intracellular glucose and fat metabolism in healthy subjects. Hyperinsulinemia and hyperglycemia per se both stimulate glucose uptake and the disposal of glucose by oxidative (Gox) and nonoxidative (Nox) metabolism. However, the intracellular metabolic fate of glucose m...
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5,967
6,740
Nonsurgical management of breast infections in nonlactating women. A word of caution. Management options for infectious mastitis have traditionally been limited to surgical drainage. With the advent of percutaneous fine needle aspiration (FNA), nonoperative treatment may be an alternative, though criteria for use hav...
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5,968
319
Effects of corticosteroids on mechanical strength of intervertebral joints and vertebrae in dogs. Dogs with hyperadrenocorticism had a higher incidence of intervertebral joint disease, i.e., disc protrusion or spondylosis. In comparing cases of hyperadrenocorticism with age- and breed-matched controls with hypothyroi...
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5,969
9,127
Physician documentation of diabetes care: use of a diabetes flow sheet and patient education clinic. We assessed two interventions designed to improve the care of patients with diabetes mellitus by documenting the complications of their disease. These were a flow sheet, included with outpatient medical records, and a...
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5,970
8,470
Oral calcium load test: diagnostic and physiologic implications in hyperparathyroidism. An oral calcium load test (CLT) (1 gm Ca/50 kg) was administered to 11 control subjects and 35 patients with overt hyperparathyroidism to assess its efficacy in diagnosis of hyperparathyroidism. All participants were placed on a l...
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5,971
543
Heart-rate variability and cardiac autonomic function in diabetes. Cardiac autonomic function was measured in 25 subjects with insulin-dependent diabetes mellitus and 11 control subjects. Autonomic integrity was assessed with standard tests of autonomic function and a new technique of measuring heart-rate variability...
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5,972
342
Tests of thyroid function: update in the diagnosis and management of thyroid disease. Current thyroid function tests give the clinician powerful tools for the accurate assessment of thyroid status in the majority of patients encountered. There are, however, a small number of clinical situations in which there appear ...
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5,973
4,360
Eruptive seborrheic keratoses in a young woman with acromegaly. The sign of Leser-Trelat, or eruptive seborrheic keratoses, is purported to be a cutaneous marker for many underlying malignancies. Elevation in levels of growth factors has been postulated to be the stimulus for the sudden eruption of multiple new sebor...
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5,974
6,873
Acute hypercalcemic crisis after an open heart operation. Acute hyperparathyroidism developed in a previously normocalcemic 64-year-old woman during the first week after a coronary operation. Prolonged QT interval in the electrocardiogram and hypercalcemia were documented on the fourth postoperative day. Neck explor...
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5,975
9,600
Anti TSH-receptor antibodies in pregnant patients with autoimmune thyroid disorder. The study was designed to test further the usefulness of the radioreceptor assay of thyroid stimulating hormone (TSH) binding inhibitory immunoglobulins (TBII) and the bioassay of thyroid stimulating antibodies (TSAb) or TSH stimulated...
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5,976
8,492
Clinicopathologic and flow cytometric DNA study of medullary thyroid carcinoma. Sixty-one patients with medullary thyroid carcinoma were investigated to establish relationships between the neoplasm's DNA content, other clinicopathologic factors, and patient survival (at least 5 years' follow-up). There were 26 (42.6%...
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5,977
6,052
Calcifications of the breast after reduction mammoplasty. Mammograms of 152 patients after mammoplasty were studied and 37 patients were noted to have calcifications. The pattern of these calcifications was studied to determine if specific characteristics could be identified. The calcifications were found to occur w...
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5,978
7,965
Distribution of elements and water in peripheral nerve of streptozocin-induced diabetic rats. Accumulating evidence suggests that alterations in Na, Ca, K, and other biologically relevant elements play a role in the mechanism of cell injury. The pathogenesis of experimental diabetic neuropathy is unknown but might in...
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5,979
3,955
Is insulinlike growth factor I associated with diabetic retinopathy? Insulinlike growth factor I (IGF-I) is the mediator of the growth-promoting effects of growth hormone and has been suspected of playing a role in the pathogenesis of proliferative diabetic retinopathy (PDR). However, previous attempts to correlate I...
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5,980
481
Comparison of HbA1 and fructosamine in diagnosis of glucose-tolerance abnormalities. Total glycosylated hemoglobin (HbA1) and fructosamine were evaluated as screening tools for detection of glucose-tolerance abnormalities in 144 asymptomatic subjects undergoing a 75-g oral glucose tolerance test. Subjects were classi...
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5,981
535
Effects of converting-enzyme inhibition on barrier function in diabetic glomerulopathy. Differential solute clearances were used to examine the effects of a 90-day course of enalapril on glomerular barrier function in 16 proteinuric patients with diabetic glomerulopathy. By day 90, plasma renin and prorenin became el...
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5,982
6,987
The influence of hyperglycemia and diabetes mellitus on immediate and 3-month morbidity and mortality after acute stroke. Fasting serum glucose, glycosylated hemoglobin, and fructosamine concentrations were determined in 304 consecutive subjects admitted with acute stroke, within 48 hours of ictus. Based on the medic...
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5,983
537
Interaction between insulin and glucose-delivery route in regulation of net hepatic glucose uptake in conscious dogs. In the presence of fixed basal levels of insulin, the route of intravenous glucose delivery (protal vs. peripheral) determines whether net hepatic glucose uptake (NHGU) occurs. Our aims were to deter...
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5,984
2,161
Follicular cell predominance in the cytologic examination of dominant thyroid nodules indicates a sixty percent incidence of neoplasia. The interpretation of aspiration cytologic smears that contain a predominance of follicular components often presents a dilemma to the clinician who is treating a patient who has a do...
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5,985
5,999
Prevalence of previously undiagnosed hypothyroidism in residents of a midwestern nursing home [published erratum appears in South Med J 1991 Jul;84(7):936] Hypothyroidism in the elderly may be associated with nonspecific symptoms. To determine the prevalence of undiagnosed hypothyroidism in residents of a skilled nur...
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5,986
480
Oral contraceptives in women with diabetes. We evaluated the association of oral contraceptive use with the presence and severity of diabetic retinopathy, hypertension, and glycosylated hemoglobin in women of childbearing age who have diabetes. Neither current or past use nor number of years of use of oral contracept...
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5,987
6,372
The mutation for medullary thyroid carcinoma with parathyroid tumors (MTC with PTs) is closely linked to the centromeric region of chromosome 10. Two new morphs (F and G) detected by the centromeric alpha satellite probe p alpha 10RP8 and D10Z1 in HinfI digests are linked to the PstI polymorphisms of D10Z1, confirming...
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5,988
475
Influenza infection and diabetes mellitus. Case for annual vaccination. Herein, epidemiological data on influenza pneumonia and mortality, results of clinical studies, and the outcome of influenza vaccination trials are reviewed. All excess mortality studies that specify for underlying disease list diabetes as one of...
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5,989
2,182
Leukoaraiosis, intracerebral hemorrhage, and arterial hypertension. To investigate whether the observed association of leukoaraiosis with intracerebral hemorrhage is direct or mediated by risk factors, we compared 116 patients with intracerebral hemorrhage confirmed by computed tomography and 155 controls without intr...
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5,990
9,178
Primary adrenal insufficiency: a new cause of reversible gastric stasis. Primary adrenal insufficiency is known to cause a wide spectrum of sometimes severe upper gastrointestinal symptoms; however, it has not previously been shown to be the cause of reversible gastric stasis. We have documented such a case in which ...
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5,991
479
Relationship of psychiatric illness to impotence in men with diabetes. Clinical data from 37 adult males with diabetes mellitus (insulin dependent, n = 22; non-insulin dependent, n = 15) who had undergone psychiatric diagnosis and peripheral nerve conduction studies were reviewed to determine whether psychiatric illne...
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5,992
6,834
Intraoperative blood pressure. What patterns identify patients at risk for postoperative complications? While monitoring blood pressure is a routine part of intraoperative management, several methods have been proposed to characterize intraoperative hemodynamic patterns as predictors of postoperative complications. ...
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5,993
3,198
Abnormal diastolic function in patients with type 1 diabetes and early nephropathy. Left ventricular diastolic function was assessed by pulsed Doppler echocardiography in non-diabetic controls (n = 11) and in patients with type 1 diabetes without microvascular disease (n = 16; diabetic controls), with microalbuminuria...
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5,994
9,867
Coronary artery disease in Chinese males without hypercholesterolaemia The aim of this study was to determine the frequency of various metabolic risk factors for coronary artery disease (CAD) in 246 male patients studied over a 2-year period. CAD was diagnosed on the basis of a history indicative of angina pectoris,...
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5,995
468
Diabetes, hyperinsulinemia, and hyperlipidemia in small aboriginal community in northern Australia. A small rural Aboriginal community in northern Australia was surveyed for diabetes, impaired glucose tolerance (IGT), hyperinsulinemia, and lipid levels. Of the 122 adults greater than 17 yr of age who participated (95...
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5,996
5,483
Suprasellar pituitary adenoma arising from the pars tuberalis: case report. A rare case of suprasellar pituitary adenoma arising from the pars tuberalis in a 53-year-old woman is presented. The tumor was located exclusively above the diaphragma sellae, and no invasion into the sella turcica was noted.
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5,997
9,866
Diagnostic applicability of intact and midregion/C-terminal parathyroid hormone assays in calcium metabolic disorders. We compared measurements of parathyroid hormone (PTH) using two assays, in order to detect intact PTH and midregion/C-terminal PTH (M/C-PTH) in a variety of calcium metabolic disorders. The series co...
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5,998
9,230
Surgical complications of continuous ambulatory peritoneal dialysis. Surgical experience with 260 consecutive patients with chronic renal failure receiving continuous ambulatory peritoneal dialysis (CAPD) at one medical center from 1980 to 1989 is reviewed. Patients received CAPD for a mean of 24.2 months (range: 3 d...
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5,999
7,693
The influence of renal function on diabetic foot ulceration. We examined the effect of renal function on the formation, severity, and outcome of diabetic foot lesions. Information was collected from a retrospective hospital chart survey and analyzed by univariate and multivariate linear regression analysis. Creatini...
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