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8,500 | 2,122 | Management of the pregnant patient with carcinoma of the breast.
The diagnosis of carcinoma of the breast during pregnancy poses a challenging dilemma.
Although once regarded as incurable, recent reports reveal similar long term survival rates for pregnant and nonpregnant patients who have carcinoma of the breast.
W... | C04 |
8,501 | 3,902 | Hormonal treatment of functional ovarian cysts: a randomized, prospective study.
Estrogen (E)/progestin therapy for functional ovarian cysts is widely used in clinical practice, but the efficacy of this treatment has not been determined in controlled trials.
In this study, we examined the effect of E/progestin admini... | C04 |
8,502 | 2,579 | Magnetic resonance imaging of radiation optic neuropathy.
Three patients with delayed radiation optic neuropathy after radiation therapy for parasellar neoplasms underwent magnetic resonance imaging.
The affected optic nerves and chiasms showed enlargement and focal gadopentetate dimeglumine enhancement.
The magneti... | C04 |
8,503 | 6,969 | Lower extremity weakness as the initial manifestation of lung cancer [published erratum appears in Arch Phys Med Rehabil 1991 Jan;72(1):61]
A 55-year-old woman had progressive lower extremity weakness.
She had an 80-pack-per-year history of cigarette smoking.
Electromyographic findings were consistent with the Lambe... | C04 |
8,504 | 6,464 | The value of nucleolar organizer regions in uveal melanoma. The Collaborative Ocular Melanoma Study Group.
Silver staining of nucleolar organizer regions is an objective method for evaluating the malignancy of a variety of tumors.
We studied 126 ciliochoroidal melanomas, three coincidental nevi that occurred in eyes ... | C04 |
8,505 | 6,907 | Malignant thymoma presenting as intracardiac tumor and superior vena caval obstruction.
A case of malignant thymoma with intracardiac infiltration and intrinsic superior vena caval obstruction due to the tumor is reported.
Intracardiac invasion by a thymoma is rare and for this reason is believed worthy of a report. | C04 |
8,506 | 2,647 | Soft tissue sarcomas of the head and neck in adults.
We reviewed the clinical records and pathologic material of 176 adults with primary soft tissue sarcomas treated at Memorial Sloan-Kettering Cancer Center between 1950 and 1985.
Seventy-two patients (41%) had low-grade sarcomas and 104 (59%) had high-grade sarcomas... | C04 |
8,507 | 6,342 | A chance to cut is a chance to cure?
Fifty-seven patients underwent local excision of an invasive distal rectal cancer as an initial operative procedure with curative intent.
Five-year survival was 82.5%, and the rectal cancer specific mortality rate was only 10.5%.
The level of wall invasion, vascular permeation, t... | C04 |
8,508 | 5,216 | Small cell carcinoma of the pancreas and biliary tract.
Four cases of anaplastic carcinoma of the pancreas or biliary tract were studied clinicopathologically and immunohistochemically.
All four cases were intermediate cell type and contained a minimum amount of microscopic foci of differentiated glandular adenocarci... | C04 |
8,509 | 4,855 | Immunoscintigraphy of ovarian cancer with indium-111-labeled OV-TL 3 F(ab')2 monoclonal antibody.
The safety and diagnostic accuracy of immunoscintigraphy with the indium-111-labeled monoclonal antibody OV-TL 3 F(ab')2(111In-OV-TL 3 F(ab')2) for diagnosis and follow-up of ovarian cancer was prospectively studied in 31... | C04 |
8,510 | 5,516 | Basement membrane of cervical adenocarcinoma: an immunoperoxidase study of laminin and type IV collagen.
The basement membrane components type IV collagen and laminin were examined immunohistochemically in 14 cases of adenocarcinoma of the cervix.
The patterns of staining in adenocarcinoma in situ, invasive adenocarc... | C04 |
8,511 | 5,459 | Ultrastructural evidence for differentiation in a human glioblastoma cell line treated with inhibitors of eicosanoid metabolism.
Human glioblastoma cells incubated in the presence of inhibitors of eicosanoid biosynthesis show decreased cellular proliferation without cytotoxicity.
We studied the ultrastructural morpho... | C04 |
8,512 | 8,814 | Fallopian tube cancer. The Roswell Park experience.
Sixty-four patients with primary fallopian tube cancer treated at Roswell Park Memorial Institute from 1964 to 1987 underwent retrospective clinicopathologic review.
In 40 patients fallopian tube cancer was the only primary, but in 24 patients primary fallopian tube... | C04 |
8,513 | 2,558 | Autologous antibodies eluted from membrane fragments in human ovarian epithelial neoplastic effusions. III. Cytotoxic potential in vitro and characterization of antigen(s).
Cyst and ascites fluids from patients with ovarian epithelial neoplasms contain immunoglobulins with antitumor activity.
Autologous antibodies bo... | C04 |
8,514 | 6,007 | Preventing colorectal cancer.
Knowledgeable patients should not die of colorectal cancer.
Increasing the intake of dietary fiber, decreasing fat consumption, and increasing the use of modern technology to detect adenomatous polyps and early cancer can greatly decrease the mortality associated with colorectal cancer. | C04 |
8,515 | 5,448 | Symptomatic pineal cyst: case report.
Pineal cysts are being described with increasing frequency since the advent of magnetic resonance imaging.
Although pineal cysts are incidental findings in as many as 4% of magnetic resonance imaging studies, symptomatic pineal cysts are quite rare.
We present a case of pineal c... | C04 |
8,516 | 8,099 | Modified Van Nes rotationplasty for osteosarcoma of the proximal tibia in children
Above-knee amputation has been the traditional treatment for osteosarcoma of the proximal tibia.
Recent advances in chemotherapy have encouraged the development of limb-salvage techniques.
Van Nes rotationplasty for malignant lesions... | C04 |
8,517 | 4,972 | Effect of tamoxifen on serum insulinlike growth factor I levels in stage I breast cancer patients.
Insulinlike growth factor I (IGF-I) has been shown to be a potent mitogen for breast cancer cells in vitro, and IGF-I receptors have been demonstrated on human primary breast neoplasms.
In a randomized, placebo-controll... | C04 |
8,518 | 2,484 | Genetics and biology of human ovarian teratomas. II. Molecular analysis of origin of nondisjunction and gene-centromere mapping of chromosome I markers.
Chromosomal heteromorphisms and DNA polymorphisms have been utilized to identify the mechanisms that lead to formation of human ovarian teratomas and to construct a g... | C04 |
8,519 | 2,532 | The prognostic significance of CA 125 half-life in patients with ovarian cancer who have received primary chemotherapy after surgical cytoreduction.
Fifty-four patients with advanced epithelial ovarian cancer were monitored with serial serum CA 125 levels after surgical cytoreduction and during multi-agent chemotherap... | C04 |
8,520 | 7,574 | Fine-needle aspiration cytology and flow cytometry of intracystic papillary carcinoma of breast
To define criteria for cytologic diagnosis of intracystic papillary carcinoma (ICPC), the authors retrospectively reviewed the fine-needle aspiration (FNA) cytologic specimens of eight cases of histologically proven ICPC o... | C04 |
8,521 | 9,981 | Cytotoxic effects of high energy shock waves in different in vitro models: influence of the experimental set-up.
High energy shock waves (electromagnetically generated, Siemens Lithostar) were studied for their effects in vitro on different (tumor) cell types.
Cells were exposed to the shock waves as a single cell su... | C04 |
8,522 | 8,788 | Carboplatin in childhood brain tumors. A Children's Cancer Study Group Phase II trial.
Between October 1985 and March 1988, Children's Cancer Study Group institutions entered 95 patients with recurrent brain tumors into a Phase II trial of carboplatin 560 mg/m2 every 4 weeks.
Complete or partial responses were observ... | C04 |
8,523 | 2,442 | Gallbladder carcinoma producing human chorionic gonadotropin.
A primary carcinoma of the gallbladder producing human chorionic gonadotropin (HCG) was encountered in an 83-yr-old Japanese woman, with elevation of HCG/beta-HCG in urine and serum.
Remarkable elevation of serum estradiol was an associated finding, with i... | C04 |
8,524 | 6,338 | Diffuse hemangiomatosis of the spleen: splenic hemangiomatosis presenting with giant splenomegaly, anemia, and thrombocytopenia.
In an elderly patient with oligosymptomatic giant splenomegaly, clinical and laboratory data were nondiagnostic, while nonhomogeneous splenic enlargement was the only finding detected by ima... | C04 |
8,525 | 8,957 | The use of interferon alpha-C in patients with metastatic renal cell carcinoma arising in a congenital solitary kidney.
Three cases of renal cell carcinoma in a congenital solitary kidney are presented.
Treatment with recombinant interferon alpha-C was administered in two cases.
A subjective response occurred in one... | C04 |
8,526 | 3,378 | A phase I study of 4'-0-tetrahydropyranyladriamycin. Clinical pharmacology and pharmacokinetics.
A Phase I study of intravenous (IV) bolus 4'-0-tetrahydropyranyladriamycin (Pirarubicin) was done in 55 patients in good performance status with refractory tumors.
Twenty-six had minimal prior therapy (good risk), 23 had ... | C04 |
8,527 | 9,177 | Peritoneal mesothelioma: an unusual cause of esophageal achalasia.
Secondary esophageal achalasia due to malignancy is a rare condition; only 53 such cases have been reported to date.
Sixty-two percent of the cases were due to gastric adenocarcinoma.
Mesothelioma of the peritoneum is an uncommon neoplasm.
The usual... | C04 |
8,528 | 9,073 | Glucocorticoids locally disrupt an array of positioned nucleosomes on the rat tyrosine aminotransferase promoter in hepatoma cells.
Transcriptional activation by steroid hormones is often associated with the appearance of a DNase I hypersensitive site resulting from a local alteration of the nucleoprotein structure of... | C04 |
8,529 | 5,456 | A case of dyschondroplasia associated with brain stem glioma: diagnosis by stereotactic biopsy.
We present a 24-year-old patient with multiple chondromas of both hands, the pelvis, the left leg, and an associated brain stem glioma.
There was no evidence of hemangioma or dyschromia, and the condition was diagnosed as ... | C04 |
8,530 | 3,749 | Determinants of cell type in patients with cancer of the lungs.
In order to evaluate the determinants of cell type in patients with primary lung cancer, we compared smoking characteristics in 1,939 patients (1,474 men and 465 women).
Patients with squamous cell carcinomas, adenocarcinomas, or small-cell carcinomas we... | C04 |
8,531 | 3,395 | Giant cell tumor of bone. A clinicopathologic and DNA flow cytometric analysis.
Flow cytometric DNA analysis was performed on 60 cases of giant cell tumor of bone and the results were correlated with the clinicopathologic features.
Tumors studied were from 31 men and 29 women whose ages ranged from 18 to 62 years (me... | C04 |
8,532 | 6,466 | Immunohistologic properties of benign and malignant mixed tumor of the lacrimal gland.
We studied the immunohistopathologic features of normal lacrimal gland, benign mixed tumor, and malignant mixed tumor of the lacrimal gland.
Primary antisera were to keratin, muscle-specific actin, vimentin, and glial fibrillary ac... | C04 |
8,533 | 8,328 | Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia.
BACKGROUND and METHODS.
We describe five patients with underlying neoplasms in whom painful mucosal ulcerations and polymorphous skin lesions developed, usually with progression to blistering eruptions on the trunk and extremitie... | C04 |
8,534 | 4,867 | Treatment planning for internal radionuclide therapy: three-dimensional dosimetry for nonuniformly distributed radionuclides.
A calculational approach is described that provides the spatially varying radiation absorbed dose, presented as isodose contours superimposed on CT images, from nonuniform and/or irregular cumu... | C04 |
8,535 | 2,005 | Hypointense renal cell carcinoma: MR imaging with pathologic correlation.
In two pathologically documented cases of renal cell carcinoma, the appearance of the tumors at magnetic resonance (MR) imaging was markedly hypointense relative to normal renal parenchyma on both T1- and T2-weighted spin-echo images.
Pathologi... | C04 |
8,536 | 228 | Mucinous adenocarcinoma of the submandibular gland.
A rare tumor not easily classifiable among published histologic categories for salivary gland tumors is reported.
The neoplasm developed within the submandibular gland of a 78-year-old woman with invasion of the mandible and metastasis to regional lymph nodes.
Hist... | C04 |
8,537 | 3,382 | Surgical treatment of brain metastases in malignant melanoma.
The authors report the results of a retrospective review of 13 patients who underwent 19 craniotomies for resection of metastatic malignant melanoma at the University of Colorado (Denver, CO) between 1983 and 1989.
There was preoperative evidence of extrac... | C04 |
8,538 | 2,068 | Carcinoma of the male breast: a review of 41 cases.
We reviewed the cases of 41 consecutive men treated for breast carcinoma from 1950 through 1987 at Vanderbilt University Affiliated Hospitals to examine controversies in and methods of therapy for this disease.
Twenty-two patients (52%) had stage I or II lesions pot... | C04 |
8,539 | 3,423 | Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients.
Colon cancers typically produce mucin.
However, it is not known whether tumor mucin plays a biological role in cancer cell behavior.
To address this issue, the expression of a mucin-associated antigen, sialosyl-Tn, was examin... | C04 |
8,540 | 2,391 | Anaplastic large cell (Ki-1) lymphoma with histiocytic phenotype simulating carcinoma.
Histiocytic and epithelial cell types share many cytomorphologic and functional characteristics; it is predictable, therefore, that corresponding malignancies might be difficult to distinguish.
Described is the case of a 52-year-ol... | C04 |
8,541 | 202 | The management of pseudomyxoma peritonei.
The management of nine patients with pseudomyxoma peritonei was reviewed.
Aggressive surgical resection of tumor is the standard of treatment, with many patients requiring multiple laparotomies.
Chemotherapy, including the use of cisplatin is not effective.
Long-term nutrit... | C04 |
8,542 | 7,772 | Can internal mammary chain treatment decrease the risk of death for patients with medial breast cancers and positive axillary lymph nodes?
The effect of internal mammary chain treatment on each type of malignant death-related event was analyzed in 1195 patients with operable breast cancer and histologically involved a... | C04 |
8,543 | 7,166 | Passage of a colon 'cast' after anoabdominal rectal resection. Report of a case.
The authors report a case of the passage of a total colonic J-pouch "cast" per anus after anoabdominal rectal resection and colonic J-pouch-anal anastomosis.
This occurred without development of cuff abscess and was not due to occlusion ... | C04 |
8,544 | 2,439 | Endoscopic ultrasonography in staging rectal cancer.
Endoscopic ultrasonography (EUS) was used to stage rectal cancer by assessing depth of invasion through bowel wall layers and/or involvement of lymph nodes.
EUS findings were correlated with histopathologic findings to discern the usefulness of this modality in pre... | C04 |
8,545 | 4,803 | Acute renal dysfunction during interleukin-2 treatment: suggestion of an intrinsic renal lesion.
Adoptive immunotherapy with interleukin-2 (IL-2) and lymphokine-activated killer (LAK) cells has been effective in treating some advanced malignancies in animals and humans.
One complication of this treatment is a reversi... | C04 |
8,546 | 8,198 | IgE receptor-mediated phosphatidylinositol hydrolysis and exocytosis from rat basophilic leukemia cells are independent of extracellular Ca2+ in a hypotonic buffer containing a high concentration of K+.
In isotonic buffer, IgE receptor-mediated exocytosis from rat basophilic leukemia cells is dependent on extracellula... | C04 |
8,547 | 5,104 | Isolated primary aldosteronism in a patient with adrenal carcinoma and XY/XXY mosaic Klinefelter's syndrome.
Although breast cancer, germ cell tumors and other neoplasms are known to occur in patients with Klinefelter's syndrome, adrenal carcinoma has not yet been reported in such patients.
We describe a rare case of... | C04 |
8,548 | 7,778 | The effect of dietary omega-3 fatty acids (fish oil) on azoxymethanol-induced focal areas of dysplasia and colon tumor incidence.
MaxEPA (MA), a fish oil high in omega-3 fatty acids, was combined with various levels of corn oil (CO), rich in omega-6 fatty acids, and fed to female CF1 mice.
The three fish oil blends w... | C04 |
8,549 | 5,245 | Diagnosis of malignant cardiac disease by endomyocardial biopsy
Among oncology patients, endomyocardial biopsy has been used primarily for the evaluation of anthracycline cardiotoxicity.
In addition, however, endomyocardial biopsy may be useful for the detection of malignant cardiac neoplasms.
Between 1982 and 1989... | C04 |
8,550 | 830 | Upper gastrointestinal pathology in familial adenomatous polyposis: results from a prospective study of 102 patients.
Multiple gastric and duodenal biopsy specimens from 102 asymptomatic patients with familial adenomatous polyposis, taken during a prospective endoscopic screening programme were examined.
One hundred ... | C04 |
8,551 | 7,887 | Elevated prostaglandin E2 levels in bronchoalveolar lavage fluid of patients with bronchogenic carcinoma.
Understanding local pulmonary immunoregulatory mechanism(s) in patients with carcinoma of the lung is an important step towards the development of innovative methods of treatment.
Prostaglandin E2 plays an integr... | C04 |
8,552 | 5,603 | The cellular composition of basal cell adenoma of the parotid gland: an immunohistochemical analysis.
Four cases of basal cell adenoma of the parotid gland were examined immunohistochemically to characterize their cellular composition.
In all cases epithelial membrane antigen and keratin were detected in the inner lu... | C04 |
8,553 | 9,354 | Lymphoproliferative disorders associated with carbamazepine.
Carbamazepine-induced lymphoproliferative disorders are relatively rare.
A 32-year-old woman developed cervical lymphadenopathy while taking carbamazepine.
Histologic evaluation of the lymph node biopsy specimen demonstrated near-total effacement of the no... | C04 |
8,554 | 7,784 | Tumor factors predicting for prognosis in metastatic breast cancer. The presence of P24 predicts for response to treatment and duration of survival.
Fifty-one patients with metastatic breast cancer were investigated to determine tumor parameters with prognostic significance.
Investigations included determinations of ... | C04 |
8,555 | 6,923 | Acute renal failure in obstructive jaundice in cholangiocarcinoma.
This study was aimed at defining the natural history of renal failure in obstructive jaundice due to cholangiocarcinoma, which is an important health problem in northeastern Thailand.
Sixty-four patients among a total of 130 patients with obstructive ... | C04 |
8,556 | 3,281 | Developmental regulation of granulocytic cell binding to hemonectin.
Hemonectin (HN), a component of the bone marrow (BM) extracellular matrix which promotes adhesion of cells in the granulocytic lineage, was purified to near homogeneity and tested for its ability to mediate attachment of normal and leukemic cells of ... | C04 |
8,557 | 8,729 | Radiobiological studies in the naevoid basal cell carcinoma syndrome.
The naevoid basal cell carcinoma syndrome is described in a 43-year-old male.
The response of dividing fibroblasts from this patient to the lethal effects of ionizing radiation was indistinguishable from that of a normal control: mean inactivation ... | C04 |
8,558 | 4,330 | Autoimmunity and malignancy.
In patients with autoimmune diseases malignancy is observed more frequently than in an age-matched control group.
In strains of mice susceptible to autoimmune diseases, the incidence of lymphoreticular malignancies is increased.
Although viruses have not been directly implicated in their... | C04 |
8,559 | 4,707 | Malignant adenolymphoma of the parotid gland: report of carcinomatous transformation.
Malignant transformation of an adenolymphoma (Warthin's tumour) is a rare event.
This paper presents a case of carcinoma arising in an adenolymphoma of the parotid gland. | C04 |
8,560 | 6,297 | Potential value of hormone receptor assay in carcinoma in situ of breast.
The estrogen receptor (ER) expression of invasive breast cancer has been extensively studied both biochemically and with specific monoclonal antibodies against ER.
Relatively few studies have attempted to characterize ER pattern in breast carci... | C04 |
8,561 | 3,425 | Parathyroid hormone-like peptide in normal and neoplastic mesothelial cells.
Mesothelioma has not been commonly reported as a cause of hypercalcemia of malignancy.
We have studied a patient with malignant mesothelioma and hypercalcemia in association with elevated plasma concentrations of parathyroid hormone-like pep... | C04 |
8,562 | 8,297 | Diagnostic significance of carcinoembryonic antigen in the differential diagnosis of malignant mesothelioma.
The histologic and cytologic distinction of malignant mesothelioma from carcinomas metastatic to the pleura or peritoneum is often problematic.
For this reason immunologic methods are being increasingly used a... | C04 |
8,563 | 8,494 | N-ras 61 oncogene mutations in Hurthle cell tumors.
Mutations of ras oncogenes are believed to play an important role in the initiation or progression of human tumors.
In thyroid tumors the incidence of ras activation by specific point mutations has been reported to range from 33% in follicular adenomas up to 60% in ... | C04 |
8,564 | 8,235 | Direct extension of laryngeal carcinoma to the skin of the neck.
Invasion of the skin of the neck by laryngeal carcinoma is relatively uncommon.
Twelve cases of cancer of the larynx fungating through the cervical skin are presented.
They mostly followed initial treatment by deep X-ray therapy or partial laryngectomy... | C04 |
8,565 | 8,939 | Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells
Orthotopic implantation of human colon carcinoma cells is useful for studying the behavior of metastatic subpopulations.
We observed that the parental line and variants of human colon carcinoma K... | C04 |
8,566 | 6,062 | Hepatic resection for advanced hepatocellular carcinoma with removal of portal vein tumor thrombi.
In 13 of 398 patients who underwent hepatectomy, tumor thrombi of the remnant portal vein was concomitantly removed by the balloon catheter method in 8, an open method under hepatic vascular exclusion in 1, and resection... | C04 |
8,567 | 6,303 | Demonstration of Lipiodol in paraffin sections using a modified silver impregnation technique.
To demonstrate postangiographic Lipiodol (LIP) in hepatocellular carcinoma (HCC) in paraffin sections, direct impregnation of formalin-fixed tissue blocks with silver nitrate (AgNO3) was followed by routine processing.
LIP ... | C04 |
8,568 | 4,532 | A nongastrin malignant ampullary tumor causing gastric acid and pepsin hypersecretion. A case report.
We report a case of multiple duodenal ulcers with gastric hypersecretion due to a nongastrin secretagogue produced by a malignant tumor of the pancreas in a 78-year-old man.
The case resembled a Zollinger-Ellison syn... | C04 |
8,569 | 8,519 | Epididymal metastasis from prostatic adenocarcinoma mimicking adenomatoid tumor.
A case of epididymal metastasis from prostatic carcinoma is presented.
The initial histologic findings were suggestive of adenomatoid tumor, but a diagnosis of metastatic adenocarcinoma of prostatic origin has been established by prostat... | C04 |
8,570 | 5,822 | Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas.
The epidermal growth factor receptor gene has been found to be amplified and rearranged in human glioblastomas in vivo.
Here we present the sequence across a splice junction of aberrant ... | C04 |
8,571 | 8,151 | Oral diseases in older adults [clinical conference]
In the case presented, a 65-year-old man with multiple dental, medical, and social problems benefited from interdisciplinary assessment and treatment.
Despite his poor oral-health status and oral-health behaviors upon admission, patient education and dental therapy ... | C04 |
8,572 | 5,739 | E1a-dependent expression of adenovirus genes in OTF963 embryonal carcinoma cells: role of E1a-induced differentiation.
Some undifferentiated F9 embryonal carcinoma cells allow adenovirus genes to be expressed independently of the E1a oncogene normally required for their activation; this has been attributed to a cellul... | C04 |
8,573 | 8,483 | The utility of circulating levels of human pancreatic polypeptide as a marker for islet cell tumors.
The measurement of plasma levels of human pancreatic polypeptide (hPP) has been reported to be clinically useful in predicting the existence of pancreatic islet cell neoplasms in patients with familial multiple endocri... | C04 |
8,574 | 5,457 | An unusual complication of silastic dural substitute: case report.
A case is presented in which a patient developed an unusual complication after the use of Silastic dural substitute.
In 1983, the patient underwent removal of a meningioma with the involved dura.
Five years later, he developed around the graft materi... | C04 |
8,575 | 8,792 | Multiagent chemotherapy in relapsed acute lymphoblastic leukemia in children.
Twenty-seven evaluable children with early first bone marrow relapse of acute lymphoblastic leukemia were treated with an intensive induction/consolidation and ongoing maintenance therapy.
Induction therapy consisted of a 35-day course of d... | C04 |
8,576 | 4,649 | Cytomegalovirus in the brain: in vitro infection of human brain-derived cells.
Models for human cytomegalovirus (HCMV) brain infection have been developed in a variety of brain-derived cells in which the factors governing virus infectivity might be studied in vitro.
Studies were initiated with brain endothelial cells... | C04 |
8,577 | 5,037 | Testicular carcinoma in patients positive and at risk for human immunodeficiency virus.
Patients with the acquired immunodeficiency syndrome are at increased risk for certain malignancies.
Because acquired immunodeficiency syndrome and testicular cancer affect primarily young men, the potential complications that acq... | C04 |
8,578 | 5,903 | Interventional radiology of the biliary tract. Intraductal radiation.
One palliative method of treating patients with a high duct cholangiocarcinoma is the use of 192Ir wire.
This is placed through the tumor, which has been previously intubated, and delivers a high local dose of radiation.
The mean survival time in ... | C04 |
8,579 | 209 | Doxorubicin for unresectable hepatocellular carcinoma. A prospective study on the addition of verapamil.
A prospective study was conducted to assess the safety and efficacy of the addition of oral verapamil to intravenous Adriamycin (doxorubicin) for the management of patients with unresectable hepatocellular carcinom... | C04 |
8,580 | 2,921 | Long-term course of patients with persistent hypercalcitoninemia after apparent curative primary surgery for medullary thyroid carcinoma.
Thirty-one patients with persistent hypercalcitoninemia after seemingly adequate primary operation for medullary thyroid carcinoma (MTC) were followed for a mean period of 11.9 year... | C04 |
8,581 | 4,941 | Mucous cell hyperplasia in an odontogenic cyst from a patient with Muir-Torre syndrome.
Mucous cell proliferation in a periapical radicular cyst from a patient with a family history of colonic malignancies and multiple sebaceous neoplasms of the skin, so-called Muir-Torre syndrome, is reported.
Such goblet cell hyper... | C04 |
8,582 | 5,282 | Efficacy and morbidity of partial laryngectomy and postoperative radiation therapy.
In recent years, we have seen increasing use of partial laryngectomies for larger lesions that were previously treated by total laryngectomy.
The resultant closer margins have made postoperative radiation therapy an important adjuvant... | C04 |
8,583 | 5,470 | Changes in intracochlear and intracanalicular nerves after acoustic neurinoma excision confirmed by magnetic resonance imaging.
Postoperative magnetic resonance imaging findings related to the vestibulocochlear and facial nerves within the internal auditory canal were analyzed in acoustic neurinomas.
T1- and proton-w... | C04 |
8,584 | 5,300 | Variations on the temporoparietal fascial flap.
An improved understanding of the vascular supply of the layers of the temporal fossa has increased the potential of this region for new and ingenious reconstructive techniques.
Separate and independently vascularized layers of this region include hair-bearing scalp, gla... | C04 |
8,585 | 3,473 | Elevated serum bromide concentrations following repeated halothane anaesthesia in a child.
A 20-month-old child received 25 brief halothane general anaesthetics over a five-week period to allow cranial irradiation treatments for a posterior fossa ependymoma.
Personality change during the last week of the treatment pr... | C04 |
8,586 | 3,396 | Hyperthermia alone in the treatment of recurrences of malignant tumors. Experience with 60 lesions.
Localized hyperthermia alone has been used for the treatment of cancer recurrences in which previous conventional therapies have failed.
Since 1983 and 1988, 57 patients with 60 lesions have been heated by means of a m... | C04 |
8,587 | 3,421 | Medroxyprogesterone acetate lowers plasma corticotropin and cortisol but does not suppress anterior pituitary responsiveness to human corticotropin releasing factor.
The endocrine action of medroxyprogesterone acetate (MPA) has been claimed to be of a glucocorticoid-like nature.
Upon clinical observation, MPA has bee... | C04 |
8,588 | 7,792 | Melanoma and soft tissue sarcoma in seven patients.
Seven patients with both melanoma and sarcoma were seen at the Dana Farber Cancer Institute (Boston, MA) over a 4-year period.
Three had additional malignant neoplasms; one of these patients also had the hereditary cutaneous malignant melanoma, dysplastic nevus synd... | C04 |
8,589 | 8,801 | Immunohistochemical demonstration of the placental form of glutathione S-transferase, a detoxifying enzyme in human gliomas.
Expression of the human placental form of glutathion S-transferase (GST-pi) in human gliomas was investigated by immunohistochemical methods, and the result was compared with that of normal huma... | C04 |
8,590 | 7,494 | Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
Familial cancer syndromes have helped to define the role of tumor suppressor genes in the development of cancer.
The dominantly inherited Li-Fraumeni syndrome (LFS) is of particular interest because of the diversity of chi... | C04 |
8,591 | 431 | Endosonography of pararectal lymph nodes. In vitro and in vivo evaluation.
One hundred thirteen patients with carcinoma of the rectum were evaluated for lymph node metastases by endorectal ultrasound.
With the use of 7.5 MHz and based on different echo patterns, two main groups of lymph nodes can be differentiated: h... | C04 |
8,592 | 9,712 | Microspectrophotometric DNA analysis in ulcerative colitis with special reference to its application in diagnosis of carcinoma and dysplasia.
The deoxyribonucleic (DNA) content was measured by microspectrophotometry in 100 specimens from 60 patients with ulcerative colitis, including six patients in whom the colitis w... | C04 |
8,593 | 7,060 | Chondrosarcoma of the larynx. Diagnosis with magnetic resonance imaging and computed tomography.
Chondrosarcomas are the most common sarcomas of the larynx.
They are generally slow-growing lesions with insidious onset of symptoms.
We are presenting a case of chondrosarcoma that recurred 10 years after excision of a ... | C04 |
8,594 | 7,451 | Rhabdomyosarcomas in the head and neck: MR imaging evaluation.
To determine the typical magnetic resonance (MR) signal intensity characteristics of rhabdomyosarcomas, short repetition time (TR)/short echo time (TE) (T1-weighted) and long TR (proton density and T2-weighted) images of 13 patients with rhabdomyosarcomas ... | C04 |
8,595 | 8,227 | Tumefactive fibroinflammatory lesions of the head and neck.
The term 'tumefactive fibroinflammatory lesion' has been used to describe a fibrosclerosing disorder which has a locally destructive nature but is characterized by a benign histological appearance.
We report five patients, over a five year period, with such ... | C04 |
8,596 | 7,109 | Chronic anaemia, hyperbaric oxygen and tumour radiosensitivity.
Anaemia is an important factor in the response of some human tumours to radiotherapy.
The outcome is also influenced by whether the treatment is given in air or high pressure oxygen (HPO).
The present study examined the relationship between anaemia and ... | C04 |
8,597 | 859 | Trends in basal cell carcinoma, squamous cell carcinoma, and melanoma of the skin from 1973 through 1987.
Major increases have occurred in the incidence of basal cell carcinoma and squamous cell carcinoma of the skin, as well as in cutaneous malignant melanoma during the period 1973 through 1987 in British Columbia.
... | C04 |
8,598 | 5,381 | Altered expression of the retinoblastoma gene product in human sarcomas.
BACKGROUND.
The retinoblastoma-susceptibility (Rb) gene is a prototype tumor-suppressor gene originally isolated from patients with heritable retinoblastoma.
This gene encodes a nuclear phosphoprotein whose expression is altered in several type... | C04 |
8,599 | 8,231 | Auro-nasopharyngeal polyp and cholesteatoma.
We report the association of an auronasopharyngeal polyp arising in a congenitally abnormal middle ear and Eustachian tube.
Subsequently, ten years after removal of the polyp and insertion of a ventilation tube, there was recurrence of the polyp in association with cholest... | C04 |
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