Unnamed: 0 int64 0 10.4k | id int64 0 10k | text stringlengths 166 4.02k | label stringclasses 23
values |
|---|---|---|---|
8,600 | 7,545 | Correlation of free phenytoin to serum albumin in cancer patients.
The objectives of this study were to compare the total and free phenytoin serum concentrations of cancer patients with hypoalbuminemia with those of cancer patients with normal serum albumin and to correlate the percentage of free phenytoin with the al... | C04 |
8,601 | 5,068 | Long term effects of gastrocystoplasty in rats.
Twenty prepubescent rats underwent microsurgical gastrocystoplasty by a technique which is described.
An equal number of control rats had their bladders opened and closed.
Rats were sacrificed at 16 to 18 months postoperatively.
There were no differences in final weig... | C04 |
8,602 | 9,363 | Soft-tissue tumor with abnormal amianthoid collagen fibers.
Electron microscopic examination of a solitary soft-tissue tumor from the face demonstrated large areas with abnormal amianthoid collagen fibers in the neoplasm.
The lesion was classified as a benign neoplasm of myofibroblasts and tentatively named a myofibr... | C04 |
8,603 | 2,097 | Role of mastectomy in breast cancer.
The surgical management of breast cancer continues to evolve in an attempt to define the ideal line between therapeutic efficacy and morbidity.
It is clear that breast cancer is a biologically heterogeneous group of diseases, and no single hypothesis explains its behavior.
The su... | C04 |
8,604 | 9,443 | Basic studies on a new material for inducing antitumor immune cells.
Recently, adoptive immunotherapy for cancer with lymphokine activated killer (LAK) cells has been widely used experimentally.
The therapy has several problems, including difficulty in handling, sterilization, and time consumption.
To solve these pr... | C04 |
8,605 | 6,144 | Radiation therapy of early (stages I and II-A) seminoma of testis after initial orchiectomy.
With initial orchiectomy and radiation therapy, the prognosis of the patients with early (Stages I and II-A) testicular seminoma is nearing almost 100 percent.
Thirty-two patients with Stage I and 13 patients with Stage II-A ... | C04 |
8,606 | 9,308 | The beta-type transforming growth factor. Mediators of cell regulation in the lung.
An increased interest in the role of growth factors in the regulation of processes concerning normal and pathologic lung physiology has spurred a flurry of research in this area.
Peptide growth factors are known to control not only ce... | C04 |
8,607 | 3,375 | Toxicity of high-dose cytosine arabinoside in the treatment of advanced childhood tumors resistant to conventional therapy. A Pediatric Oncology Group study.
Experience with high-dose cytosine arabinoside (HDAC) in pediatric solid tumors is limited.
Sixteen children with solid tumors resistant to conventional therapi... | C04 |
8,608 | 7,577 | Diagnosis and localization of prostate carcinoma by fine-needle aspiration cytology and correlation with histologic whole-organ sections after radical prostatectomy.
Twenty-nine patients with clinical stage T1-2, NO, MO prostate carcinoma were treated by retropubic radical prostatectomy.
Diagnosis was made by fine-ne... | C04 |
8,609 | 7,959 | Neodymium: YAG laser hysteroscopy in large submucous fibroids.
The preoperative use of a potent, subcutaneously injected gonadotropin-releasing hormone agonist (GnRH-a) was evaluated in a series of 60 women with large submucosal fibroids.
Myomectomy by hysteroscopy and Nd:YAG laser was easily performed.
In 12 cases,... | C04 |
8,610 | 2,858 | Soluble interleukin-2 receptors in cerebrospinal fluid from individuals with various neurological disorders.
Soluble interleukin-2 (IL-2R) levels in the cerebrospinal fluid (CSF) were studied in infectious, inflammatory, degenerative, and neoplastic disorders to evaluate their usefulness as a marker for the presence o... | C04 |
8,611 | 8,948 | Cryoprobe as a "handle" for resection of metastatic liver tumors.
Resection of metastatic liver tumors can be a difficult and risky procedure.
Using a cryoprobe as a "handle" can greatly facilitate resection by providing a taut surface for transection and improving visualization of ductal and vascular structures.
In... | C04 |
8,612 | 873 | The relationship of pemphigus to neoplasia.
A statistically increased incidence of malignancy has been observed in patients with pemphigus.
A review of the literature reveals 42 cases of nonthymic malignancies and 18 cases of thymic malignancies.
A significant predominance of men, with mean age at onset of 50 years,... | C04 |
8,613 | 3,399 | Effectiveness of periodic checkup by ultrasonography for the early diagnosis of hepatocellular carcinoma.
Periodic checkup by ultrasonography was conducted on patients with chronic liver diseases for early detection of hepatocellular carcinoma.
In 19 months, a total of 2004 examinations were performed on a total of 6... | C04 |
8,614 | 9,312 | Cell-to-cell communication and the control of growth.
Growth of transformed cells is inhibited by cell-to-cell communication with normal cells.
This communication is regulated by certain oncogenes that alone or in cooperation can block the communication. | C04 |
8,615 | 3,333 | The importance of prognostic factors in the individual treatment of patients with disseminated germ cell tumours.
Following chemotherapy for disseminated testicular cancer, 55 patients underwent surgery because of residual tumour.
The histological findings were viable tumour in 12 patients, mature teratoma in 12 and ... | C04 |
8,616 | 3,275 | All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship.
All-trans retinoic acid induces leukemic cells from patients with acute promyelocytic leukemia (M3) to differentiate in vitro to mature granulocytes which express the CD15 antigen and are capable of respira... | C04 |
8,617 | 8,296 | Utility of frozen-section evaluation of lymph nodes in the staging of bronchogenic carcinoma at mediastinoscopy and thoracotomy.
We conducted a retrospective analysis of the utility of frozen-section diagnoses in determining lymph node status at mediastinoscopy in 122 consecutive patients with bronchogenic carcinoma.
... | C04 |
8,618 | 4,291 | Androgen response to endogenous insulin secretion during the frequently sampled intravenous glucose tolerance test in normal and hyperandrogenic women.
Women with ovarian hyperandrogenism frequently have insulin resistance, whose underlying mechanism remains to be determined.
In the present study we have investigated... | C04 |
8,619 | 3,330 | Distribution of bony metastases in prostatic carcinoma.
Fifty-five prostate cancer and 55 breast cancer patients with positive bone scintigrams were studied.
The pattern of spread in the axial skeleton and pelvis showed differences between the 2 groups.
This difference was not related primarily to bone volume at the... | C04 |
8,620 | 763 | A surgical approach to the cervicothoracic spine.
We describe a method for approaching the lower cervical and upper thoracic spine, the brachial plexus and related vessels.
The method involves the elevation of the medial corner of the manubrium, the sternoclavicular joint, and the medial half of the clavicle on a ped... | C04 |
8,621 | 5,688 | When epilepsy masquerades as heart disease. Awareness is key to avoiding misdiagnosis.
Autonomic neural impulses that accompany discharges during a seizure can cause a variety of cardiac manifestations, including cardiac arrhythmias, sudden death, anginal chest pain, neurogenic pulmonary edema, and symptoms of pheochr... | C04 |
8,622 | 5,554 | Management of macular puckers associated with retinal angiomas.
Monocular visual loss in four patients was caused by epiretinal macular membranes associated with peripheral retinal capillary angiomas or angioma-like lesions.
Three patients had solitary vascular lesions and one had two discrete vascular lesions.
All ... | C04 |
8,623 | 7,437 | Combined tensor fasciae latae musculocutaneous flap and sartorius musculocutaneous flap for the repair of wide defects of the lower leg.
The tensor fasciae latae musculocutaneous flap has great advantages for reconstruction of the abdominal wall, but the medial border of its territory is limited to the thigh.
In orde... | C04 |
8,624 | 9,032 | Interleukin-2 immunotherapy in children.
Immunotherapy with interleukin (IL)-2 possesses great potential in the treatment of immune-mediated diseases and cancers.
However, only a few reports on a small number of children have appeared in the literature.
From March 1988 to March 1989, 11 children and adolescents were... | C04 |
8,625 | 4,828 | Drug-induced DNA damage and tumor chemosensitivity.
Cytotoxic drugs act principally by damaging tumor-cell DNA.
Quantitative analysis of this interaction provides a basis for understanding the biology of therapeutic cell kill as well as a rational strategy for optimizing and predicting tumor response.
Recent advance... | C04 |
8,626 | 9,623 | Lack of late skin necrosis in man after high-dose irradiation using small field sizes: experiences of grid therapy.
Out of a total of 437 patients with superior vena caval syndrome or advanced malignancy, given single-dose grid radiotherapy, four survived to 7 years.
The dose to the skin under each of the 77 holes in... | C04 |
8,627 | 9,716 | Role of upper gastrointestinal investigations in a screening study for colorectal neoplasia.
Should patients with positive faecal occult blood screening tests who are free of colorectal neoplasia undergo upper gastrointestinal investigation? Altogether 16,985 faecal occult blood tests were completed in a group of 18,8... | C04 |
8,628 | 8,468 | Multiple parathyroid adenomas: report of thirty-three cases.
An increasing number of patients with primary hyperparathyroidism are found to have two or three enlarged parathyroid glands.
Of 865 patients successfully operated on by one surgeon (J.N.A.), multiple enlarged parathyroid glands (adenomas) were found and re... | C04 |
8,629 | 8,509 | Radical prostatectomy versus expectant primary treatment in stages I and II prostatic cancer. A fifteen-year follow-up.
A fifteen-year follow-up of a prospective, randomized study comparing placebo with radical prostatectomy as the primary treatment of early prostatic cancer is presented.
A total of 111 patients with... | C04 |
8,630 | 4,714 | Multiple primary malignancies in patients with malignant tumours of the nasal cavities and paranasal sinuses.
The incidence of multiple primary malignancies (MPM) was analysed in 1297 patients with malignant tumours of the nasal cavities and paranasal sinuses.
The patients were followed for a minimum of six years or ... | C04 |
8,631 | 9,253 | Multimodal therapy in locally advanced breast carcinoma.
Among 879 patients treated for breast cancer between 1975 and 1984, advanced disease was found in 125 (14%).
A subgroup of 34 (4%) presented with untreated locally advanced disease without demonstrable distant metastases at the time of diagnosis (stage IIIB = T... | C04 |
8,632 | 8,701 | Intraventricular diamorphine via an Ommaya shunt for intractable cancer pain.
We describe two patients in whom diamorphine was administered into the intraventricular space via an Ommaya reservoir, producing excellent pain relief.
The use of this technique for long term administration of analgesia is reviewed. | C04 |
8,633 | 3,296 | Induction of donor-type chimerism in murine recipients of bone marrow allografts by different radiation regimens currently used in treatment of leukemia patients.
Three radiation protocols currently used in treatment of leukemia patients before bone marrow transplantation (BMT) were investigated in a murine model (C57... | C04 |
8,634 | 8,791 | Conservative surgery and radiation therapy for soft tissue sarcoma of the wrist, hand, ankle, and foot.
Seventy-eight patients with soft tissue sarcoma (STS) arising in the distal extremities--wrist, hand, finger, ankle, foot, and toe--who were treated with conservation surgery and radiation therapy were studied retro... | C04 |
8,635 | 8,469 | Endosonography in the localization of parathyroid tumors: a preliminary study.
A preoperative transesophageal exploration of the parathyroids by endosonography was performed on 23 patients with primary hyperparathyroidism.
The system used was a 7.5 MHz transducer mounted on the tip of an endoscope with an external di... | C04 |
8,636 | 844 | Activation and inducer subset phenotype of the lymphocytic infiltrate around epidermally derived tumors.
An in situ analysis of the mononuclear cell infiltrate found in association with a range of benign, premalignant, and malignant epidermal tumors is described.
The predominant cell phenotype was that of the recentl... | C04 |
8,637 | 7,026 | Decrease in cerebral metabolic rate of glucose after high-dose methotrexate in childhood acute lymphocytic leukemia.
We measured changes in the regional cerebral metabolic rate of glucose (rCMRGlu) using 18F-fluorodeoxyglucose and positron emission tomography for the assessment of neurotoxicity in childhood acute lymp... | C04 |
8,638 | 6,798 | Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor-reactive T cells.
We compared T-cell proliferative responses to acetylcholine receptor (AChR) and to purified protein derivative (PPD) (of tuberculin) of hyperplastic thymus, thymoma, and blood cells from patients with myasthenia gravis (... | C04 |
8,639 | 9,364 | Extramedullary hematopoiesis in a bronchial carcinoid tumor. An unusual complication of agnogenic myeloid metaplasia.
A case of bronchial carcinoid tumor with foci of extramedullary hematopoiesis is presented.
The patient had a 6-year history of agnogenic myeloid metaplasia and hepatosplenomegaly.
All three hematopo... | C04 |
8,640 | 9,183 | Liver abscess complicating intratumoral ethanol injection therapy for HCC.
We report a patient who developed multiple liver abscesses and sepsis caused by lactobacilli after the percutaneous intratumoral injection of ethanol for hepatocellular carcinoma.
We diagnosed the liver abscess at an early stage because of a t... | C04 |
8,641 | 8,233 | Giant enterocystoma within an infant's tongue.
A rare developmental cyst within the tongue and submandibular triangle of a male infant containing heterotopic gastric and intestinal epithelium (enterocystoma) is described and its derivation discussed.
This cyst was of such a size as to cause feeding difficulties and p... | C04 |
8,642 | 8,804 | Prognostic significance of type IV collagen and laminin immunoreactivity in urothelial carcinomas of the bladder.
Invasion of a carcinoma involves the degradation and penetration of the subepithelial basement membrane (BM).
This phenomenon might be used for histopathologic evaluation of neoplasms of the bladder.
The... | C04 |
8,643 | 7,428 | Mammographic measurements before and after augmentation mammaplasty.
Thirty-five augmented women underwent mammography using both the standard implant-compression technique and, when possible, the implant-displacement technique; all had preaugmentation film-screen mammography available for evaluation.
The area of mam... | C04 |
8,644 | 8,121 | Marjolin's ulcer: a review and reevaluation of a difficult problem.
The formation of an epidermoid carcinoma in nonhealing scar tissue, a Marjolin's ulcer, is a well described neoplasm.
These lesions are, however, frequently overlooked and often inadequately treated.
This paper reviews six cases of scar-tissue carci... | C04 |
8,645 | 3,376 | Endoscopic screening of early esophageal cancer with the Lugol dye method in patients with head and neck cancers.
The poor prognosis for esophageal cancer could be improved if lesions were detected at an early stage.
To detect early esophageal cancer, endoscopic screening of the esophagus with the Lugol dye method wa... | C04 |
8,646 | 3,808 | Diagnosis of metastatic lesions to the stomach by salvage cytology. A report of three cases.
Secondary neoplasms of the stomach are rare and are often clinical and diagnostic problems.
Three patients with bleeding "volcano-like" ulcers were diagnosed by combined endoscopic "salvage" cytology and surgical biopsy as ha... | C04 |
8,647 | 8,952 | Surgical wound infection and cancer among the elderly: a case control study.
Surgical wound infection occurs in fewer than 5% of operations.
Nevertheless, it represents the second most common type of hospital-acquired infection and results in increased morbidity and mortality.
As with all nosocomial infections, the ... | C04 |
8,648 | 4,982 | Prospective study of the frequency and size distribution of polyps missed by colonoscopy.
An important determinant in interpreting the results of colorectal polyp chemoprevention trials is the rate of polyps missed during colonscopic examination.
We prospectively examined 90 patients by tandem colonoscopy performed b... | C04 |
8,649 | 6,145 | Management of superficial G2 (pTa and pT1) bladder cancer.
A total of 143 patients with superficial G2 (pTa, pT1) bladder cancer (48 G2pTa; 95 G2pT1) presenting between 1970 through 1987 were reviewed.
Of 48 patients with G2pTa followed for up to eighteen years, G3 recurrence developed only in 1 (2.0%), and invasive ... | C04 |
8,650 | 6,841 | Surgical management of pheochromocytoma with the use of metyrosine.
Despite recommended preoperative preparation with alpha-adrenergic blockers, severe hemodynamic instability may occur during operations to resect pheochromocytoma.
We combined the alpha-blocker phenoxybenzamine with the tyrosine hydroxylase inhibitor... | C04 |
8,651 | 2,402 | Estimation of PR and ER by immunocytochemistry in breast cancer. Comparison with radioligand binding methods.
Immunocytochemical assays for progesterone receptor (PR) using monoclonal antirabbit PR antibodies (PR-ICA) and for estrogen receptor (ER) (ER-ICA) were compared with radioligand binding (dextran-coated charco... | C04 |
8,652 | 6,483 | Flow cytometric analysis of the mechanism of methylmercury cytotoxicity.
Flow cytometric analysis of murine erythroleukemic cells (MELC) exposed in vitro to 2.5 to 7.5 mumol/l (micromolar) methylmercury (MeHg) reveals a dose-dependent decrease in the rate of DNA synthesis (rate of passage through the S phase of the ce... | C04 |
8,653 | 8,941 | Mechanism of antitumor activity of tumor necrosis factor alpha with hyperthermia in a tumor necrosis factor alpha-resistant tumor.
Cells from a radiation-induced fibrosarcoma (RIF-1) are exceedingly resistant to tumor necrosis factor alpha (TNF-alpha) in vitro.
We tested whether the addition of mild hyperthermia (42.... | C04 |
8,654 | 6,980 | Primary malignant peritoneal mesothelioma. A report of seven cases and a review of the literature.
Mesothelioma of the peritoneum is a rare malignant neoplasm easily mistaken by both surgeon and pathologist for one of the more common neoplasms of the abdomen.
Review of our records from metropolitan-area hospitals for... | C04 |
8,655 | 332 | Combined laminoplasty and posterolateral fusion for spinal canal surgery in children and adolescents.
Spinal deformities, especially kyphosis and instability, after laminectomy for tumors and other diseases, are major clinical problems.
Since 1981, combined laminoplasty and posterolateral fusion for the prevention of... | C04 |
8,656 | 2,567 | Oral contraceptives and breast cancer.
Among women in general the risk of breast cancer through 59 years of age does not appear to be affected appreciably by the use of oral contraceptives.
Nonetheless, concern continues to be expressed about the effects of early age at first use, long-term duration of use, formulati... | C04 |
8,657 | 26 | HLA class I and class II antigen expression on squamous cell carcinoma of the head and neck.
We compared human major histocompatibility (HLA) class I and class II antigen expression on squamous cell carcinoma of the head and neck with that on normal mucosa.
Frozen sections of a consecutive series of 30 squamous cell ... | C04 |
8,658 | 3,011 | Pulmonary blastoma with malignant melanoma component.
Pulmonary blastomas are rare primary tumors that consist of tubular or glandular structures embedded in an undifferentiated mesenchymal stroma.
Focal cartilage, bone, and skeletal muscle as well as squamous differentiation have been described in these tumors.
We ... | C04 |
8,659 | 3,390 | The physical state of human papillomavirus 16 DNA in cervical carcinoma and cervical intraepithelial neoplasia.
Cervical carcinomas and cervical intraepithelial neoplasias (CIN) were analyzed for the presence of human papillomavirus (HPV) DNA using Southern blot hybridization.
Of the five HPV types examined (HPV type... | C04 |
8,660 | 4,016 | Colonic lipomas: outcome of endoscopic removal.
Colonic lipomas are benign adipose tumors which are usually submucosal.
With the increase in the number of endoscopic procedures being performed, these tumors are often detected incidentally at colonoscopy.
Although the risks of removing these tumors have been recogniz... | C04 |
8,661 | 8,787 | The influence of autologous lymphokine-activated killer cell infusions on the toxicity and antitumor effect of repetitive cycles of interleukin-2.
Twenty patients with refractory malignancies were treated with a protocol evaluating the addition of ex vivo-activated autologous lymphokine-activated killer (LAK) cells to... | C04 |
8,662 | 4,811 | Quantitative analysis of antibody localization in human metastatic colon cancer: a phase I study of monoclonal antibody A33.
A33 is a mouse immunoglobulin G2a (IgG2a) monoclonal antibody (mAb) that detects a heat-stable, protease- and neuraminidase-resistant epitope.
The antigen is homogeneously expressed by virtuall... | C04 |
8,663 | 8,925 | Autoradiographic evaluation of monoclonal antibodies' access to melanoma-associated antigens in melanoma xenografts.
Autoradiography of nude mice bearing human malignant melanoma xenografts was performed to characterize the distribution pattern of radioiodinated anti-melanoma monoclonal antibodies (MoAb) and fragments... | C04 |
8,664 | 8,739 | Pachyonychia congenita complicated by hidradenitis suppurativa: a family study.
A family is described in which five of the six members with the Jackson-Lawler type of pachyonychia congenita also had varying degrees of hidradenitis suppurativa.
We suggest an association between this type of pachyonychia congenita and ... | C04 |
8,665 | 8,786 | The Patterns of Care Outcome Study for cancer of the uterine cervix. Results of the Second National Practice Survey.
This report summarizes the outcome results of the Patterns of Care Study (PCS) of cancer of the uterine cervix from 565 patients treated in 1978.
The 5-year survival with no evidence of disease was: St... | C04 |
8,666 | 5,030 | Randomized phase II evaluation of carboplatin and CHIP in advanced transitional cell carcinoma of the urothelium. The Eastern Cooperative Oncology Group.
A total of 83 patients with metastatic transitional cell carcinoma who had previously received no systemic therapy entered a randomized phase II evaluation of carbop... | C04 |
8,667 | 7,094 | Association of bcl-1 rearrangements with lymphocytic lymphoma of intermediate differentiation.
Previous studies using classical cytogenetics have demonstrated the presence of the t(11;14) (q13;q32) chromosomal translocation in some cases of lymphocytic lymphoma of intermediate differentiation (IDL), a distinct type of... | C04 |
8,668 | 2,234 | Is urethral sparing at cystectomy a safe procedure?
Urethrectomy is performed with cystectomy when the neoplasm is multifocal, at the bladder neck, or associated with carcinoma in situ (CIS).
The records of the most recent 20 patients treated by radical cystectomy at our institution were reviewed.
In 50 percent of t... | C04 |
8,669 | 7,536 | Aqueductal (pencil) glioma presenting as neurogenic pulmonary edema: a case report.
A case of neurogenic pulmonary edema due to hydrocephalus, without initial neurological deficit, is described.
Computed tomography demonstrated a ring enhancing lesion in the tectum of the mesencephalon obstructing the aqueduct of Syl... | C04 |
8,670 | 691 | Prognostic factors of hepatocellular carcinoma in the west: a multivariate analysis in 206 patients.
To investigate the prognostic factors in Western patients with hepatocellular carcinoma, 206 patients with confirmed diagnoses of hepatocellular carcinoma were studied in terms of survival.
All patients were diagnosed... | C04 |
8,671 | 2,659 | Treatment selection for carcinoma of the base of the tongue.
Between 1974 and 1984, 173 patients were treated for squamous cell carcinoma of the tongue base.
Fifty-four patients had T1 or T2 primaries, while 115 patients had T3 or T4 tumors (4 were not staged).
Lymph node metastasis was present in 120 patients.
Ear... | C04 |
8,672 | 7,204 | Epidermal growth factor regulates the in vitro sensitivity of human ovarian carcinoma cells to cisplatin.
Cisplatin (DDP) is the most effective drug for the treatment of human ovarian cancer, but the mechanisms that determine sensitivity to the cytotoxic action of DDP are not well understood.
Treatment of two human o... | C04 |
8,673 | 9,649 | Thallous chloride uptake and DNA profile in parathyroid adenomas.
Thallium isotope scintigraphy is used to localize parathyroid adenomas but the mechanism underlying the technique is poorly understood.
While larger adenomas are reliably localized the results are less certain for small tumours.
This study explores th... | C04 |
8,674 | 9,633 | Regional chemotherapy for colorectal liver metastases: a phase II evaluation of targeted hepatic arterial 5-fluorouracil for colorectal liver metastases.
The results of systemic chemotherapy in patients with liver metastases from colorectal cancer remain dismal.
Regional chemotherapy has been advocated as a method of... | C04 |
8,675 | 5,452 | Occult vascular malformations of the optic chiasm: magnetic resonance imaging diagnosis and surgical laser resection.
Angiographically occult vascular malformations of the optic nerve and chiasm are extremely rare.
Before the advent of magnetic resonance imaging (MRI), it was difficult to diagnose these lesions preop... | C04 |
8,676 | 6,905 | Squamous carcinoma metastatic to the sternum.
A 63-year-old man had a 10 x 16-cm sternal mass 18 months after a second aortocoronary bypass operation.
The resected lesion was a metastatic tumor of squamous histology.
No primary tumor was found.
The diagnostic work-up and treatment options are presented. | C04 |
8,677 | 6,452 | Preferential mitogenic activity for myoblast-like cells can be extracted from uterine leiomyoma tissues.
The presence of mitogen(s) in leiomyoma extracts stimulating cells with the fibroblast, myoblast, and osteoblast phenotype was documented.
Mitogenic activity in leiomyoma extracts was acid stable and sensitive to ... | C04 |
8,678 | 7,455 | Colonic stenoses: use of oral barium when retrograde flow is completely obstructed on barium enema studies.
Forty patients with complete obstruction to retrograde barium flow on barium enema examinations, without clinical or radiographic evidence of obstruction, were studied further with orally administered barium in ... | C04 |
8,679 | 2,174 | Pulmonary disease following intravesical BCG treatment.
Bacillus Calmette-Guerin (BCG) is an attenuated strain of Mycobacterium bovis that has been used in the treatment of malignant disease for over 20 years and for the treatment of bladder cancer since 1976.
Major complications of this treatment are infrequent.
We... | C04 |
8,680 | 4,975 | Antitumor activity of liposome-encapsulated doxorubicin in advanced breast cancer: phase II study.
Previous studies in animals have demonstrated liposome-encapsulated doxorubicin (LED) has substantially less cardiac toxicity than free doxorubicin but retains antitumor activity.
In a phase I clinical study of LED, the... | C04 |
8,681 | 5,095 | The prognostic value of modal deoxyribonucleic acid in low grade, low stage untreated prostate cancer.
We selected for a prospective surveillance study 167 patients with untreated grades 1 and 2 prostate cancer.
The tumors were classified regarding modal deoxyribonucleic acid value (ploidy) by flow cytometry, cytolog... | C04 |
8,682 | 3,289 | New type of Bcr/Abl junction in Philadelphia chromosome-positive chronic myelogenous leukemia.
A new and rare type of Bcr/Abl junction between exon C3 of the 3' portion of the Bcr gene and Abl exon 2 has been identified in the leukemic cells of two Ph1-positive chronic myelogenous leukemia patients in chronic phase.
... | C04 |
8,683 | 9,125 | Breast cancer: the military's experience at Wilford Hall USAF Medical Center.
We reviewed the experience with breast cancer at Wilford Hall USAF Medical Center for the years 1978 through 1988.
A total of 868 cases were identified in the Wilford Hall Tumor Registry; overall 5-year and 10-year survivals were 63% and 39... | C04 |
8,684 | 9,310 | Genetic strategies of tumor suppression.
The evaluation of the cancer cell is a complex multigene process.
Tumor suppressor genes that are lost or inactivated, as well as genes that are overexpressed, play key roles in tumor progression.
The identification of overexpressed genes has been expedited by the presence of... | C04 |
8,685 | 4,844 | Epithelial cyst of the fourth ventricle. Case report.
A case of epithelial cyst in the fourth ventricle of a 4-year-old child is described.
A single epithelial layer with a clear basement membrane lining the cyst wall was observed.
There were no prominent histological findings to suggest a pathogenesis for this cyst... | C04 |
8,686 | 2,937 | Analysis of prognostic factors and clinicopathological staging of thymoma
The prognostic value of four clinical variables (age and sex of patients, association with myasthenia gravis, and clinical stage) and histological type was analyzed in 83 consecutive patients with thymoma, histologically classified as cortical,... | C04 |
8,687 | 5,083 | Outpatient flexible cystoscopy and fulguration of recurrent superficial bladder tumors.
Flexible cystoendoscopy and fulguration were used in the outpatient management of 185 patients with superficial bladder tumors followed for 24 months.
This method provided optimal surveillance for recurrence and successful tumor c... | C04 |
8,688 | 2,550 | Suppression of serum insulin level by diazoxide does not alter serum testosterone or sex hormone-binding globulin levels in healthy, nonobese women.
Suppression of serum insulin levels with diazoxide is associated with a decrease in serum testosterone and an increase in serum sex hormone-binding globulin in obese wome... | C04 |
8,689 | 9,059 | Multisurface method of pattern separation for medical diagnosis applied to breast cytology.
Multisurface pattern separation is a mathematical method for distinguishing between elements of two pattern sets.
Each element of the pattern sets is comprised of various scalar observations.
In this paper, we use the diagnos... | C04 |
8,690 | 4,699 | Alternating cisplatinum and VAC ineffective in end stage squamous cell carcinoma of the head and neck.
Sixteen patients with end stage squamous cell carcinoma of the head and neck were admitted to a phase II study of alternating courses of cisplatinum (100 mg/m2) and VAC (vincristine 1.4 mg/m2, adriamycin 50 mg/m2, cy... | C04 |
8,691 | 8,754 | Leukaemia complicating treatment for Hodgkin's disease: the experience of the British National Lymphoma Investigation.
OBJECTIVE--To determine the incidence of and risk factors for the development of secondary acute leukaemia and myelodysplasia in patients treated in British National Lymphoma Investigation's studies o... | C04 |
8,692 | 4,812 | An early phase II study of CPT-11: a new derivative of camptothecin, for the treatment of leukemia and lymphoma.
An early phase II study of a new camptothecin analog and an inhibitor of topoisomerase I, CPT-11, was conducted in 62 patients with refractory leukemia and lymphoma by four different treatment schedules in ... | C04 |
8,693 | 208 | Association of disease-free survival and percent of ideal dose in adjuvant breast chemotherapy.
The relationship between percent of ideal dose and disease-free survival was examined in 256 Stage II and III patients who participated in a 2-year breast adjuvant chemotherapy trial consisting of cyclophosphamide, methotre... | C04 |
8,694 | 3,418 | Perinatal infection of human T-lymphotropic virus type I, the etiologic virus of adult T-cell leukemia/lymphoma. DNA amplification of specific human T-lymphotropic virus type I sequences.
A gene amplification technique, polymerase chain reaction, was used to detect human T-lymphotropic virus type I (HTLV-I), the etiol... | C04 |
8,695 | 9,723 | Stomal adenocarcinoma in Crohn's disease.
Malignant change occurring at the site of a stoma in two patients with proved Crohn's disease is described.
Patients with ulcerative colitis have an increased risk of colonic malignancy and Crohn's disease is also associated with both small and large bowel carcinoma.
Most pr... | C04 |
8,696 | 3,986 | Detection of duodenal gastrinomas by operative endoscopic transillumination. A prospective study.
The ability of operative endoscopic transillumination of the bowel wall to detect duodenal gastrinoma was evaluated prospectively in 26 patients with the Zollinger-Ellison syndrome.
The results were assessed by explorato... | C04 |
8,697 | 6,309 | Microstaging of squamous cell carcinomas.
The clinical classification of squamous cell carcinoma, which was established primarily by the International Union Against Cancer (UICC), does not permit optimal estimation of expected metastasis.
The authors' results indicate that metastasis can be more accurately estimated ... | C04 |
8,698 | 4,239 | Transthyretin receptors on human astrocytoma cells.
Transthyretin (TTR), a transport protein for T4 and retinol-binding protein, is the principal T4-binding protein of cerebrospinal fluid.
Its function in regard to the delivery of its ligands and in other respects is unclear.
The binding of [125I] TTR to cultured hu... | C04 |
8,699 | 2,531 | Successful conservative management of primary nonmetastatic cervical choriocarcinoma.
Primary cervical choriocarcinoma is a rare disease; since 1915 only about 60 cases have been published.
The case presented here can be defined as primary cervical choriocarcinoma since it fulfills all the criteria delineated previou... | C04 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.