Unnamed: 0 int64 0 10.4k | id int64 0 10k | text stringlengths 166 4.02k | label stringclasses 23
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|---|---|---|---|
900 | 466 | Complement-fixing antibodies to sympathetic and parasympathetic tissues in IDDM. Autonomic brake index and heart-rate variation.
We describe herein complement-fixing anti-adrenal medullary (CF-ADM) and anti-sympathetic ganglia (CF-SG) antibodies in insulin-dependent diabetes mellitus (IDDM).
This study describes comp... | C18 |
901 | 3,035 | Utility of computed tomography for surveillance of small abdominal aortic aneurysms. Preliminary report.
To assess the ability of computed tomography to predict the potential for expansion of small abdominal aortic aneurysms, we analyzed the computed tomographic scans of 30 patients who had two or more abdominal compu... | C18 |
902 | 2,492 | Haplotype analysis of the human apolipoprotein B mutation associated with familial defective apolipoprotein B100.
Haplotype analysis was conducted on the mutant allele of 14 unrelated subjects heterozygous for a mutation in the codon for amino acid 3500 of human apolipoprotein B100.
This mutation is associated with d... | C18 |
903 | 8,634 | Short stature, mental retardation, and hypoparathyroidism: a new syndrome.
Eight children (four boys and four girls) with extreme failure to thrive, dysmorphic features, developmental delay, hypoparathyroidism, and abnormal skeletal survey were studied.
They were the products of seven consanguinous marriages, two of ... | C18 |
904 | 7,962 | Allelic variants at insulin-receptor and insulin gene loci and susceptibility to NIDDM in Welsh population.
A cohort of 132 well-documented White Welsh non-insulin-dependent diabetic (NIDDM) subjects were genotyped for 5 restriction-fragment-length polymorphisms (RFLPs) at the insulin-receptor gene (IRG) locus and a p... | C18 |
905 | 7,713 | Ticlopidine treatment reduces the progression of nonproliferative diabetic retinopathy. The TIMAD Study Group.
The Ticlopidine Microangiopathy of Diabetes study (TIMAD), a randomized, double-masked, placebo-controlled trial, assessed the effect of this antiplatelet agent (ticlopidine hydrochloride) in reducing the pro... | C18 |
906 | 368 | Peripheral venous monitoring with acute blood volume alteration: cuff-occluded rate of rise of peripheral venous pressure.
We investigated the use of a new peripheral hemodynamic monitoring technique, the cuff-occluded rate of rise of peripheral venous pressure (CORRP), in the assessment of volume status in fluid over... | C18 |
907 | 9,130 | Screening for slight albuminuria: a comparison of selected commercially available methods.
Slight albuminuria predicts clinically significant nephropathy in patients with insulin-dependent diabetes mellitus (IDDM) and early death in patients with non-insulin-dependent diabetes mellitus (NIDDM).
This study compares fo... | C18 |
908 | 6,197 | Cardiac fluoroscopy for the diagnosis of coronary artery disease: a meta analytic review.
To evaluate variability in the reported accuracy of fluoroscopically detected coronary calcific deposits for predicting angiographic coronary disease, we applied meta analysis to 13 consecutively published reports comparing the r... | C18 |
909 | 487 | Combined insulin-sulfonylurea therapy in treatment of NIDDM.
For the past few years, interest has focused on the combination of insulin and sulfonylurea in the search for effective treatments for non-insulin-dependent diabetes mellitus (NIDDM) patients who fail on oral hypoglycemic agents.
Although several studies ha... | C18 |
910 | 6,359 | Temporary loss of limb function secondary to soft tissue calcification in a patient with rhabdomyolysis-induced acute renal failure.
A case of unusually severe soft tissue calcification with temporary loss of limb function in a patient with rhabdomyolysis-induced acute renal failure (ARF) is described.
A large dose o... | C18 |
911 | 470 | Impact of intensive educational approach to dietary change in NIDDM.
The aim of this study was to compare the effects of an intensive educational approach incorporating longer time, greater simplicity, repetition, and cognitive motivational techniques with a conventional one in subjects with established non-insulin-de... | C18 |
912 | 4,244 | Effect of central obesity on regulation of carbohydrate metabolism in obese patients with varying degrees of glucose tolerance.
It has been proposed that central obesity, by virtue of the enhanced lipolytic activity of abdominal adipose tissue, leads to higher plasma FFA concentrations, which, in turn, decrease both h... | C18 |
913 | 455 | Lack of cutaneous hyperemia in response to insulin-induced hypoglycemia in IDDM.
Cutaneous blood flow was measured with the laser Doppler technique and by recording cutaneous O2 tension on the forearm and forehead in nine young adult patients with insulin-dependent diabetes mellitus (IDDM) and nine sex- and age-matche... | C18 |
914 | 478 | Effect of isocaloric substitution of chocolate cake for potato in type I diabetic patients.
Traditional dietary advice given to people with diabetes includes eliminating simple sugars (primarily sucrose) from the diet.
Many people have difficulty following this recommendation.
Because patients with type I (insulin-d... | C18 |
915 | 2,733 | Use of Doppler flow velocity waveform analysis in detection of initial diabetic microangiopathy.
Doppler flow velocity waveform analysis (FVWFA), recorded from the dorsalis pedis artery (DPA) and the radial artery (RA), was performed on 36 women in attempting to detect an initial diabetic microangiopathy (DM).
The st... | C18 |
916 | 911 | Type 2 diabetes mellitus and periodontal disease.
The relationship between type 2 diabetes mellitus and periodontal disease was evaluated in 2,878 Pima Indians of the southwestern United States.
Two independent measures of periodontal disease, probing attachment loss and radiographic bone loss, were used to compare p... | C18 |
917 | 3,055 | X-linked spinal muscular atrophy (Kennedy's syndrome). A kindred with hypobetalipoproteinemia.
Kennedy's syndrome, X-linked adult-onset bulbospinal muscular atrophy, has been described in over 30 families.
The characteristic distribution of weakness creates a recognizable syndrome, augmented by frequent findings of t... | C18 |
918 | 4,785 | Lambert Eaton syndrome: autonomic neuropathy and inappropriate antidiuretic hormone secretion in a patient with small cell carcinoma of the lung.
A patient with small cell carcinoma of the lung developed asymptomatic autonomic neuropathy, inappropriate antidiuretic hormone (ADH) secretion and Lambert Eaton myasthenic ... | C18 |
919 | 531 | Absence of brown product FFI in nondiabetic and diabetic rat collagen.
Accumulation of brown products in long-lived proteins might be an important factor in determining long-term diabetic complications.
Fluorescent chromophore 2-(2-furoyl)-4-(5)-(2-furanyl)-1H-imidazole (FFI), isolated from hydrolyzed brown products ... | C18 |
920 | 5,600 | Nitrendipine-induced gingival hyperplasia. First case report.
Drug-induced gingival hyperplasia is well documented within the literature.
It has been associated with phenytoin, cyclosporine, and calcium channel blocking agents.
Nitrendipine is an experimental calcium channel blocking agent that also appears to cause... | C18 |
921 | 9,761 | Carbohydrate malabsorption. Its measurement and its contribution to diarrhea.
The major purpose of this research was to gain insight into the effect of carbohydrate malabsorption on fecal water output.
To do this we measured daily fecal output of total carbohydrate, reducing sugars, and organic acids (a product of ba... | C18 |
922 | 6,267 | Urinary organic acid excretion during feeding of medium-chain or long-chain triglyceride diets in patients with non-insulin-dependent diabetes mellitus.
Medium-chain triglycerides (MCTs) are absorbed and metabolized differently from long-chain triglycerides (LCTs).
Recent data indicate that MCTs may be useful as a di... | C18 |
923 | 53 | Hyponatraemia secondary to an inappropriately high release of antidiuretic hormone in cardiac tamponade.
A spontaneous intrapericardial haemorrhage caused cardiac tamponade in a 29 year old paraplegic man who was being treated with warfarin.
The associated persistent hyponatraemia, which was believed to be caused by ... | C18 |
924 | 2,061 | Anxiety levels and cancer fear in patients admitted for elective operations.
Patients who are to have elective operations project varying degrees of anxiety, and many spontaneously express fear (without basis) that their operation involves a diagnosis of malignancy.
To measure total, covert, and overt anxiety objecti... | C18 |
925 | 6,043 | The predictive value of needle localization mammographically assisted biopsy of the breast.
This study was done to review critically the experience at the University of California at San Diego in needle localization mammographic biopsy of the breast with regard to use and accuracy in identifying early carcinoma of the... | C18 |
926 | 6,183 | Silent myocardial ischemia and infarction in diabetics with peripheral vascular disease: assessment by dipyridamole thallium-201 scintigraphy.
We investigated the incidence of silent myocardial ischemia and infarction as assessed by dipyridamole thallium scintigraphy in 30 diabetic patients with peripheral vascular di... | C18 |
927 | 7,500 | Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
The current studies were designed to determine whether chronic overexpression of low density lipoprotein (LDL) receptors in the liver would protect mice from the increase in plasma LDL-cholesterol that is induced by high-fat diet... | C18 |
928 | 6,572 | Hypothermia and acidosis worsen coagulopathy in the patient requiring massive transfusion.
Massive transfusion may cause abnormalities of electrolytes, clotting factors, pH, and temperature and may occur in a scenario of refractory coagulopathy and irreversible shock.
Identification of correctable variables to improv... | C18 |
929 | 3,814 | Devices for insulin administration.
There is a significant need for revised, safe, and more effective insulin-delivery methods than subcutaneous injections in the treatment of both type I (insulin-dependent) and type II (non-insulin-dependent) diabetes.
The aim of this review is to describe the rationale and methods ... | C18 |
930 | 4,261 | Clinical review 16: Parathyroid hormone-related proteins: coming of age in the 1990s.
The last 3 yr have yielded a fertile harvest of new information on the HHM clinical syndrome and on the novel peptide hormone family responsible for the syndrome.
Whereas the clinical riddle enshrouding the HHM syndrome first posed ... | C18 |
931 | 527 | Effect of hyperinsulinemia and hyperglycemia on intracellular glucose and fat metabolism in healthy subjects.
Hyperinsulinemia and hyperglycemia per se both stimulate glucose uptake and the disposal of glucose by oxidative (Gox) and nonoxidative (Nox) metabolism.
However, the intracellular metabolic fate of glucose m... | C18 |
932 | 7,242 | The need for accurate nutrition survey methodology: the South Carolina experience.
Assessment of two nutrition-related risk factors, obesity and fat intake, was completed on a representative sample of South Carolina adults.
Obesity estimates determined from self-reported heights and weights were less than prevalences... | C18 |
933 | 6,059 | Disc swelling in an adult diabetic patient [clinical conference]
A patient with insulin dependent adult onset diabetes presented with bilateral disc edema and minimal visual dysfunction.
Initial work-up excluded an intracranial lesion, and a lumbar puncture revealed a normal opening pressure.
The patient developed p... | C18 |
934 | 5,150 | Ten-year follow-up of behavioral, family-based treatment for obese children
Using a prospective, randomized, controlled design, we examined the effects of behavioral family-based treatment on percent overweight and growth over 10 years in obese 6- to 12-year-old children.
Obese children and their parents were random... | C18 |
935 | 482 | Sulfonylureas. Why, which, and how?
Although controversies remain as to the usefulness of sulfonylureas, most evidence is in favor of their use in many if not patients with non-insulin-dependent diabetes mellitus.
When used properly, sulfonylureas improve insulin secretion and action, and these effects may be maintai... | C18 |
936 | 6,387 | Contrast nephropathy in azotemic diabetic patients undergoing coronary angiography.
PURPOSE: To evaluate the incidence of, risk factors for, and outcome of contrast nephropathy in azotemic diabetic patients undergoing coronary angiography.
PATIENTS AND METHODS: Fifty-nine insulin-dependent diabetics with a mean serum... | C18 |
937 | 9,127 | Physician documentation of diabetes care: use of a diabetes flow sheet and patient education clinic.
We assessed two interventions designed to improve the care of patients with diabetes mellitus by documenting the complications of their disease.
These were a flow sheet, included with outpatient medical records, and a... | C18 |
938 | 6,568 | Pouch outlet obstruction following vertical ring gastroplasty for morbid obesity.
We have experienced a 14% (38 of 264 patients) incidence of pouch outlet obstruction following vertical ring gastroplasty.
Initial management consisted of dilatation in 34 of 38 patients (94%).
Ten of 34 patients (29%) were spared reop... | C18 |
939 | 3,941 | Insulinlike activity of new antidiabetic agent CP 68722 in 3T3-L1 adipocytes.
We examined the in vitro effects of CP 68722, a novel antidiabetic agent, in 3T3-L1 adipocytes.
CP 68722 stimulated 2-deoxyglucose uptake in the absence of insulin.
At least 30 min of incubation were required for stimulation of uptake.
Th... | C18 |
940 | 3,958 | Contribution of impaired muscle glucose clearance to reduced postabsorptive systemic glucose clearance in NIDDM.
The reduced postabsorptive rates of systemic glucose clearance in non-insulin-dependent diabetes mellitus (NIDDM) are thought to be the consequence of insulin resistance in peripheral tissues.
Although the... | C18 |
941 | 7,964 | Experimental diabetes increases insulinlike growth factor I and II receptor concentration and gene expression in kidney.
Insulinlike growth factor I (IGF-I) is a mitogenic hormone with important regulatory roles in growth and development.
One of the target organs for IGF-I action is the kidney, which synthesizes abun... | C18 |
942 | 543 | Heart-rate variability and cardiac autonomic function in diabetes.
Cardiac autonomic function was measured in 25 subjects with insulin-dependent diabetes mellitus and 11 control subjects.
Autonomic integrity was assessed with standard tests of autonomic function and a new technique of measuring heart-rate variability... | C18 |
943 | 6,277 | Physical growth and development of children with type 1 glycogen-storage disease: comparison of the effects of long-term use of dextrose and uncooked cornstarch.
Thirteen patients with type 1 glycogen-storage disease (GSD-1) were studied to compare the effects on biochemical control and growth of 2 y of therapy with i... | C18 |
944 | 486 | Metabolic effects of combination glipizide and human proinsulin treatment in NIDDM.
The effects of 3 mo of treatment with a combination of glipizide and human proinsulin were studied in a small group of closely monitored patients.
The patients had non-insulin-dependent diabetes mellitus (NIDDM) and poor glucose regul... | C18 |
945 | 2,367 | Serial evaluation of lipid profiles and risk factors for development of hyperlipidemia after cardiac transplantation.
To determine the prevalence, time course and factors responsible for hyperlipidemia after heart transplantation, 83 consecutive 1-year survivors were studied.
By 1 year, 83% of patients had serum tota... | C18 |
946 | 2,254 | The changing epidemiology of diabetes mellitus among Navajo Indians.
Although early descriptions of diabetes mellitus among Navajo Indians characterized the disease as an infrequent and "benign chemical abnormality," the prevalence of diabetes and its complications among Navajos appears to have increased substantially... | C18 |
947 | 3,029 | Immediate breast reconstruction following mastectomy is as safe as mastectomy alone.
We evaluated wound complications and potential risk factors after mastectomy with immediate breast reconstruction and compared them with similar data after modified radical mastectomy.
The incidences of infection, seroma, hematoma, a... | C18 |
948 | 521 | Association of elevated fasting C-peptide level and increased intra-abdominal fat distribution with development of NIDDM in Japanese-American men.
The Japanese-American population of King County, Washington, is known to have a high prevalence of non-insulin-dependent diabetes mellitus (NIDDM).
As part of a community-... | C18 |
949 | 5,195 | Removal of an inorganic acid load in subjects with ketoacidosis of chronic fasting.
When a large inorganic acid load is ingested by normals, the proton load is eliminated because the rate of excretion of ammonium can rise to 200 to 300 mmol/day.
In subjects with ketoacidosis of chronic fasting, such a large increase ... | C18 |
950 | 488 | Will sulfonylurea treatment of impaired glucose tolerance delay development and complications of NIDDM?
The chronic hyperglycemia of non-insulin-dependent diabetes mellitus (NIDDM) evolves gradually and is usually preceded by more transient hyperglycemia, classified as impaired glucose tolerance (IGT).
Already in thi... | C18 |
951 | 5,650 | Dexamethasone effects on the hospital course of infants with bronchopulmonary dysplasia who are dependent on artificial ventilation.
A randomized double-blind placebo-controlled trial was conducted to evaluate the effects of enterally administered dexamethasone on the hospital course of infants with bronchopulmonary d... | C18 |
952 | 7,601 | Growth in obese children treated for obesity.
This study assesses the growth patterns during a 5-year period in children aged 6 to 12 years treated for obesity using behavioral family-based treatment procedures.
Previous studies have suggested a decrease in height velocity after weight reduction, but these results di... | C18 |
953 | 6,873 | Acute hypercalcemic crisis after an open heart operation.
Acute hyperparathyroidism developed in a previously normocalcemic 64-year-old woman during the first week after a coronary operation.
Prolonged QT interval in the electrocardiogram and hypercalcemia were documented on the fourth postoperative day.
Neck explor... | C18 |
954 | 5,829 | Molecular mapping of the mouse db mutation.
Diabetes (db) is an autosomal recessive mutation located in the midportion of mouse chromosome 4 that results in profound obesity with hyperphagia, increased metabolic efficiency, and insulin resistance.
To clone this gene and generate a molecular map of the region around t... | C18 |
955 | 6,052 | Calcifications of the breast after reduction mammoplasty.
Mammograms of 152 patients after mammoplasty were studied and 37 patients were noted to have calcifications.
The pattern of these calcifications was studied to determine if specific characteristics could be identified.
The calcifications were found to occur w... | C18 |
956 | 7,965 | Distribution of elements and water in peripheral nerve of streptozocin-induced diabetic rats.
Accumulating evidence suggests that alterations in Na, Ca, K, and other biologically relevant elements play a role in the mechanism of cell injury.
The pathogenesis of experimental diabetic neuropathy is unknown but might in... | C18 |
957 | 459 | Incidence of IDDM during 1984-1986 in population aged less than 30 yr. Residents of Turin, Italy.
The goal of this study was to measure the incidence of insulin-dependent diabetes mellitus (IDDM) during 1984-1986 in residents of Turin, Italy, aged less than 30 yr.
The primary data source was the list of all subjects ... | C18 |
958 | 9,191 | Cigarette smoking, adiposity, non-insulin-dependent diabetes, and coronary heart disease in Japanese-American men.
PURPOSE: Coronary heart disease has been described to be increased with both glucose intolerance and cigarette smoking.
All three of these have also been reported to be associated with central adiposity ... | C18 |
959 | 3,955 | Is insulinlike growth factor I associated with diabetic retinopathy?
Insulinlike growth factor I (IGF-I) is the mediator of the growth-promoting effects of growth hormone and has been suspected of playing a role in the pathogenesis of proliferative diabetic retinopathy (PDR).
However, previous attempts to correlate I... | C18 |
960 | 7,378 | Increased testosterone in type I diabetic subjects with severe retinopathy.
Diabetic retinopathy rarely occurs before puberty, suggesting that changes in sex hormones may influence the development of this condition.
The authors measured serum testosterone, estradiol, DHEA-S, and sex hormone binding globulin levels in... | C18 |
961 | 6,363 | The NT 1311 polymorphism of G6PD: G6PD Mediterranean mutation may have originated independently in Europe and Asia.
A polymorphic site exists in exon 11 of G6PD: in the wild-type enzyme, nucleotide (NT) 1311 is a C, but is some individuals from diverse populations a T is present instead.
Nine of 54 X chromosomes from... | C18 |
962 | 430 | The starved colon--diminished mucosal nutrition, diminished absorption, and colitis.
Nutrition of colonic epithelial cells is mainly from short chain fatty acids (SCFAs) produced by bacterial fermentation in the colonic lumen.
n-Butyrate contributes more carbon of oxidation to epithelial cells than glucose or glutami... | C18 |
963 | 6,287 | Self-reported weight and height.
The error in self-reported weight and height compared with measured weight and height was evaluated in a nationally representative sample of 11,284 adults aged 20-74 y from the second National Health and Nutrition Examination Survey of 1976-1980.
Although weight and height were report... | C18 |
964 | 9,782 | Hyperglycemia-induced B cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background.
The role of pancreatic B cell dysfunction in the phase preceding clinical onset of insulin-dependent and non-insulin-dependent diabetes mellitus has been much debated.
In this... | C18 |
965 | 6,352 | Etiology of hypercalcemia in hemodialysis patients on calcium carbonate therapy.
Fourteen of 39 dialysis patients (36%) became hypercalcemic after switching to calcium carbonate as their principal phosphate binder.
In order to identify risk factors associated with the development of hypercalcemia, indirect parameters... | C18 |
966 | 9,088 | Immunological evidence for the accumulation of lipoprotein(a) in the atherosclerotic lesion of the hypoascorbemic guinea pig.
Lipoprotein(a) [Lp(a)] is an extremely atherogenic lipoprotein.
Lp(a) has been found in the plasma of humans and other primates, but until now only in a few other species.
The mechanism by wh... | C18 |
967 | 7,259 | The importance of context in choosing nutritional indicators.
Nutritional indicators are used to screen, diagnose, and evaluate interventions in individuals.
They are also used in populations to ascertain and place under surveillance the magnitude of nutritional problems, their location and causes, and to evaluate th... | C18 |
968 | 6,987 | The influence of hyperglycemia and diabetes mellitus on immediate and 3-month morbidity and mortality after acute stroke.
Fasting serum glucose, glycosylated hemoglobin, and fructosamine concentrations were determined in 304 consecutive subjects admitted with acute stroke, within 48 hours of ictus.
Based on the medic... | C18 |
969 | 8,976 | Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages.
Insulin-dependent diabetes mellitus (IDDM) is a disease with an autoimmune aetiology.
The non-obese diabetic mouse is a good spontaneous animal model of the human disease, with IDDM developing in 50-80% of female mice by... | C18 |
970 | 2,978 | Fast and effective treatment of malignant hypercalcemia. Combination of suppositories of calcitonin and a single infusion of 3-amino 1-hydroxypropylidene-1-bisphosphonate.
Seventeen patients with malignant hypercalcemia were treated with a combination of a single dose of 3-amino 1-hydroxypropylidene-1-bisphosphonate (... | C18 |
971 | 3,448 | Death at cardiac catheterization: coronary artery embolization of calcium debris from Ionescu-Shiley bioprosthesis.
The case described is a death due to embolization of calcium debris from a bioprosthesis, dislodged at cardiac catheterization.
As more bioprosthetic valves are implanted, and more of them fail long-ter... | C18 |
972 | 6,273 | Cholesterol-lowering effects of soluble-fiber cereals as part of a prudent diet for patients with mild to moderate hypercholesterolemia.
Soluble-fiber breakfast cereals were examined for their cholesterol-lowering ability in 58 male patients with mild to moderate hypercholesterolemia in a randomized, double-blind, pla... | C18 |
973 | 8,921 | Depletion of alcohol (hexanol) dehydrogenase activity in the epidermis and jejunal mucosa in Sjogren-Larsson syndrome.
Using a histochemical technique, we have demonstrated a consistent deficiency of alcohol (hexanol) dehydrogenase activity within the epidermis and jejunal mucosa of patients with Sjogren-Larsson syndr... | C18 |
974 | 4,246 | Beta-cell cytoadherent lymphocytes in some subjects at risk for type 1 (insulin-dependent) diabetes: progression to diabetes within 2 years.
The increased binding in vitro of CD3 CD4 T-lymphocytes from type 1 (insulin-dependent) diabetic patients to beta-cell membrane antigens compared to lymphocytes from control subj... | C18 |
975 | 5,796 | Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes.
Familial hypercholesterolemia is an inherited disease in humans that is associated with coronary artery disease and is caused by a deficiency of the receptor that mediates ... | C18 |
976 | 4,504 | Cholesterol screening in 5,719 self-referred elderly subjects.
To assess the frequency of hypercholesterolemia as a potential major public health problem in the elderly, we studied 5,719 self-referred subjects greater than age 60 and 11,890 less than or equal to 60 years, whose nonfasting capillary blood cholesterol l... | C18 |
977 | 541 | Increased preproinsulin mRNA in pancreatic islets incubated with islet cell-stimulating antibodies from serums of type I diabetic patients.
We recently described autoantibodies that stimulate the release of insulin from pancreatic beta-cells both in vitro and in vivo.
The aim of this study was to establish whether is... | C18 |
978 | 524 | Absence of angiogenesis-inhibitory activity in aqueous humor of diabetic rabbits.
We studied inhibitory activity of angiogenesis in the eye to explore the formation of new blood vessels in diabetic microvascular diseases.
When we examined the effects of extracts from various ocular tissues of nondiabetic rabbits on t... | C18 |
979 | 2,312 | Renal effects of angiotensin-converting enzyme inhibition in congestive heart failure.
Some studies report that inhibition of angiotensin-converting enzyme (ACE) improves renal function in patients with congestive heart failure, whereas others report that renal deterioration is a frequent complication of treatment wit... | C18 |
980 | 8,135 | The association of xerostomia and inadequate intake in older adults.
Recent studies indicate that nearly one in five older adults has xerostomia (dry mouth).
Salivary gland dysfunction and/or inadequate saliva increases the difficulty of these older adults in obtaining proper nutrition.
Problems in lubricating, mast... | C18 |
981 | 592 | The uncoupling of biliary lipid from bile acid secretion by organic anions in the rat.
A number of organic anions has been shown to inhibit biliary phospholipid and cholesterol secretion without affecting bile acid secretion.
However, the mechanism of this uncoupling phenomenon is still unclear.
This study shows a c... | C18 |
982 | 3,811 | Insulin use in NIDDM. Rationale based on pathophysiology of disease.
Because basal hyperglycemia is a major feature in non-insulin-dependent diabetes mellitus, diabetes control can be monitored by the fasting blood glucose concentration.
A hierarchical sequence of therapies is proposed in which the major aim is to ma... | C18 |
983 | 2,806 | A prospective assessment of the Garren-Edwards Gastric Bubble and bariatric surgery in the treatment of morbid obesity.
Morbid obesity is a serious medical hazard, and effective alternatives to surgery have been unsuccessful.
In 1985, the Garren-Edwards Gastric Bubble (GEGB) was offered as an adjunct to dietary and b... | C18 |
984 | 4,008 | Adaptive hyperphagia in patients with postsurgical malabsorption.
The specific nutritional consequences of malabsorption after small-bowel surgery were studied in a consecutive series of 48 ambulatory patients who had had small-bowel resection (n = 43) or bypass (n = 5) and in 10 patients who had an ileal pouch (n = 1... | C18 |
985 | 7,382 | Indications and results of relaxing retinotomy.
The authors report their results of a consecutive series of 40 eyes undergoing relaxing retinotomy during vitrectomy to achieve retinal reattachment for the following indications: proliferative vitreoretinopathy (PVR), 21 eyes (52%); trauma, 10 eyes (25%); diabetic retin... | C18 |
986 | 9,870 | Elevation of skeletal muscle isoform of serum creatine kinase in heterozygous familial hypercholesterolaemia.
Serum creatine kinase (CK) is an important adjunct in the diagnosis of myocardial infarction or in monitoring for the side-effects of drugs.
We report elevation of CK in patients with untreated heterozygous f... | C18 |
987 | 4,482 | The effects of moderate exercise training on nutrient intake in mildly obese women.
The relationship between moderate exercise training (five 45-minute sessions per week, brisk walking at 62 +/- 2% VO2 max for 15 weeks) and changes in nutrient intake was investigated in a group of 36 sedentary, mildly obese women.
Th... | C18 |
988 | 7,010 | A subluxing arthropathy associated with the anti-Jo-1 antibody in polymyositis/dermatomyositis.
Of 180 patients with polymyositis/dermatomyositis (PM/DM) seen at the University of Pittsburgh and affiliated hospitals since 1975, 21 of 100 tested positive for the anti-Jo-1 antibody.
Sixteen of the 21 patients were wome... | C18 |
989 | 9,865 | Continuous subcutaneous insulin infusion (CSII), multiple injections (MI) and conventional insulin therapy (CT) in self-selecting insulin-dependent diabetic patients. A comparison of metabolic control, acute complications and patient preferences.
Continuous subcutaneous insulin infusion (CSII) and multiple injections ... | C18 |
990 | 3,135 | Effects of felodipine on urinary albumin excretion and metabolic control in hypertensive non-insulin-dependent diabetics.
The effect of a blood pressure reduction by 10 mg extended release felodipine once daily on urinary albumin excretion (UAE) as well as the possible diabetogenic effect of felodipine was studied.
A... | C18 |
991 | 2,494 | Definitive prenatal diagnosis for type III glycogen storage disease.
Prenatal diagnosis for type III glycogen storage disease was performed by using (1) immunoblot analysis with a polyclonal antibody prepared against purified porcine-muscle debranching enzyme and (2) a qualitative assay for debranching-enzyme activity... | C18 |
992 | 3,818 | Alcoholic ketoacidosis.
Alcoholic ketoacidosis is characterized by a metabolic acidosis with an elevated anion gap.
It generally is seen in the chronic alcoholic patient who has recently gone on a "binge" that was terminated because of complaints such as nausea, vomiting or abdominal pain.
Caloric intake is diminish... | C18 |
993 | 480 | Oral contraceptives in women with diabetes.
We evaluated the association of oral contraceptive use with the presence and severity of diabetic retinopathy, hypertension, and glycosylated hemoglobin in women of childbearing age who have diabetes.
Neither current or past use nor number of years of use of oral contracept... | C18 |
994 | 3,800 | Dynamic CT scanning of pancreatic duct after secretin provocation in pancreas divisum.
Variations in pancreatic duct diameter at CT scanning and serum pancreatic amylase response following secretin administration were studied in 29 patients with pancreas divisum and unexplained upper abdominal pain.
Eleven healthy in... | C18 |
995 | 8,590 | Glucose 6-phosphate dehydrogenase deficiency and cataract of patients in northern Sardinia.
We determined the activity level of glucose 6-phosphate dehydrogenase in 467 patients with cataract from northern Sardinia.
Of 226 men, 18 (8%) had glucose 6-phosphate dehydrogenase deficiency.
Of 241 women, 30 (12%) were het... | C18 |
996 | 9,121 | Morbidly obese patients' perceptions of social discrimination before and after surgery for obesity.
Morbidly obese patients' perceptions of obesity-related prejudice and discrimination were assessed before and 14 months after operation for obesity.
Preoperatively, the 57 consecutive patients perceived overwhelming pr... | C18 |
997 | 3,570 | Diabetic patients have abnormal cerebral autoregulation during cardiopulmonary bypass.
We tested the hypothesis that insulin-dependent diabetic patients with coronary artery bypass graft surgery experience altered coupling of cerebral blood flow and oxygen consumption.
In a study of 23 patients (11 diabetics and 12 a... | C18 |
998 | 6,260 | Obesity and iron status in menstruating women.
The relationship between iron stores and obesity in menstruating women was studied in 20 obese and 20 nonobese women matched for age and contraception.
Although no difference was observed in serum iron or total-iron-binding capacity, the obese group showed significantly ... | C18 |
999 | 3,768 | Pulmonary malignant angioendotheliomatosis. Presentation with fever and syndrome of inappropriate antidiuretic hormone.
A 64-year-old man presented with protracted fever, hyponatremia, and mononeuritis multiplex.
Inappropriate antidiuretic hormone secretion was established.
The absence of pulmonary infiltrates precl... | C18 |
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