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ART001517044
oai_dc
청소년기의 구조적 척추 측만증 치험 2례
A Clinical Trial for Two Adolescent Patients with Structural Spinal Scoliosis
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "홍상준(동서한방병원 한방소아과); 최가혜(동서한방병원); 송인선(동서한방병원); 이철휘(동서한방병원 침구과)" ]
목적 :본 연구의 목적은 추나요법으로 치료된 청소년기 척추 측만증 환아 2례를 보고함이다. 방법 :우리는 x-ray를 사용하여 2례의 청소년기 환자를 검사하였다. 이 환자들은 구조적 척추측만증으로 진단되었다. 우리는 자침과 추나요법을 상용하였고 Cobb's angle과 VAS를 통해 치료 효과를 평가하였다. 결과, 결론 :우리는 치료후 다음과 같은 효과를 확인하였다. 한 케이스에서는 흉추에서 Cobb's angle 이 19˚에서 10.6˚로 8.4˚호전되어 44.2%의 교정도를 보였고 VAS 는 5에서 1-2로 개선되었다. 다른 케이스에서는 요추에서 Cobb's angle 이 11.3˚에서 7˚로 4.3˚호전되어 38%의 교정도를 보였고 VAS 는 7에서 1-2로 개선되었다.
한의학
null
kci_detailed_000248.xml
ART001517040
oai_dc
제 6 뇌신경 마비로 진단된 痲痺性 斜視 患兒 1例 報告
One Clinical Study on Strabismus Patient of Abducence Nerve Paralysis with Oriental Medicine
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "천진홍(동국대학교 한방소아과); 민상연(동국대학교); 김장현(동국대학교)" ]
목적 : 이 연구는, 제6 뇌신경 마비로 진단된 마비성 사시 환아를 한의학적 방법으로 치료한 증례 보고이다. 소아에게 있어서 마비성 사시에 대한 한의학적 치료법의 안전성과 효과를 확인하고자 한다. 방법 : 양방의료기관 안과에서 각종 검사를 통해 제6 뇌신경(외전신경) 마비로 진단받고 경과관찰만 하던 환아 1명을, 2010년 3월 6일부터 2010년 3월 30일까지 한약, 침, 뜸, 탄소광선 요법 등을 시술하면서 경과를 관찰하였다. 결과 : 마비성 사시인 소아에게 한의학적인 치료법을 시술하였을 경우, 24일만에 완치되었으며 부작용이나 재발은 발생하지 않았다. 따라서 이 치료법을 바탕으로 치료 프로토콜을 제작할 것이다. 결론 : 외전신경마비로 인한 사시 환아에게, 단순한 경과관찰이나 수술요법 보다는 한의학적 치료가 안전하며 효과적이다.
한의학
null
kci_detailed_000248.xml
ART001517099
oai_dc
경희의료원 한방소아·청소년과 외래 환자의 주소증에 대한 연구 (2009년 3월~2010년 2월)
A Study of the Chief Complaint of Pediatric Outpatients in the Kyung Hee Oriental Medicine Hospintal
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "최민형(경희대학교 한방소아과); 김덕곤(경희대학교); 이진용(경희대학교)" ]
목적: 한방 소아•청소년과 외래에 방문하는 환자들의 주소증의 최신 경향을 하는 것이 이번 연구의 목적이다. 방법: 2009년 3월부터 2010년 2월까지 경희대학교 한방병원 한방소아과를 내원한 소아•청소년 환자 3024명의 초진기록지를 분석하였다. 결과: 환자의 연령대는 만 1세가 가장 많았고, 나이가 증가함에 따라 급격히 감소하였다. 가장 많이 방문하는 시기는 8월, 가장 적게 방문하는 시기는 11월이었다. 가장 많이 방문한 질환의 계통은 호흡기, 성장, 보약, 소화기, 신경•정신, 피부의 순서였고, 단일 주소증은 성장, 보약, 식욕부진•편식, 비부비동염, 감기, 아토피피부염, 경기의 순서로 나타났다. 만 1~6세에서는 호흡기 계통, 만 7세 이상에서는 성장 계통이 가장 많이 방문하였다. 단일 주소증으로는 만 0세에는 경기, 만 1~3세에서는 보약, 만 4~6세에서는 비부비동염, 만 7세 이상에서는 성장 환자가 가장 많이 방문하였다. 보약과 호흡기 계통은 8월에 크게 증가였고, 성장과 소화기 계통은 9월에 크게 증가하였다. 단일 주소증은 성장 환자의 방문이 가장 많았지만, 9월과 11월에는 보약 환자가 가장 많았다. 결론: 가장 많이 방문하는 질환의 계통은 호흡기계 질환이었고, 단일 주소증은 성장이었다. 소아•청소년에 대한 더 많은 자료의 축적과, 이를 바탕으로 단일 질환에 대한 다양한 연구가 핖요하다.
한의학
null
kci_detailed_000248.xml
ART001517100
oai_dc
성장에 대한 유전적·환경적 요인의 영향
Effect of Genetic and Environmental Factors on Growth
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "최민형(경희대학교 한방소아과); 김덕곤(경희대학교); 이진용(경희대학교)" ]
목적: 성장에 영향을 주는 유전적•환경적 요인을 파악하고, 이를 이용하여 최종 신장을 예측한다. 방법: 소아•청소년 환자 1352명의 신장측정과 설문조사를 통해 얻어진, 유전적•환경적 요인과 키 백분위수 사이에 상관분석과 회귀분석을 하였다. 결과: 키백분위수와 상관성을 갖는 요소는 MPH, NBW, 식욕부진, 소화불량, 아침식사, 아토피, 수면의 질이다. MPH는 적당한 크기(moderate)의 관련성, NBW와 식욕부진은 약간(fair)의 관련성, 소화불량, 아토피피부염, 아침식사, 수면의 질은 선형적인 관련성을 보이지만, 관련성이 약했다(poor). 상관성을 갖는 요소와 키백분위수 사이에 얻어진 회귀식은 26.9%의 예측력으로 크지 않았다. 유전적 요인만을 고려한 회귀식의 예측력은 20.4%였다. 키백분위수에 가장 큰 영향을 미치는 요소는 MPH였다. 식욕부진은 출생시체중에 비해 더 큰 영향력을 가졌다. 소화불량과, 아침식사, 아토피 피부염과 수면의 질은 크기는 작지만 비슷한 크기의 영향력을 가지고 있었다. 결론: 부모의 신장이 최종신장에 가장 큰 영향을 미치고, 출생시체중, 식욕부진, 소화불량, 아침식사, 아토피 피부염, 수면의 질도 영향을 미친다.
한의학
null
kci_detailed_000248.xml
ART001516396
oai_dc
한방병원 응급실에 내원한 소아 환자에 관한 임상적 고찰
Clinical Study of the Pediatric Patients Who Had Visited Emergency Room(ER) at Oriental Medical Hospital
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이유진(대구한의대학교); 백정한(대구한의대학교)" ]
목적 : 한방병원 응급실에 내원한 소아 환자의 특성 및 질병양상을 파악하여 응급실에서 시행되는 한방치료의 질적 향상, 다양한 치료방법을 확립하여, 소아 환자 진료를 활성화하고자 한다. 방법 : ○○한의대학교부속○○한방병원 응급실에 내원한 만 15세 이하의 소아환자 371명을 대상으로 병력기록부를 중심으로 자료를 분석하였다. 결과 :1. 내원 환아의 평균연령은 4.28세였고, 1-3세의 유아기가 36.7%로 가장 많았다. 2. 월별 내원 분포는 6월에 내원한 환아 수가 11.6%로 가장 많았다. 요일별로는 일요일에 내원한 환아가 29.1%로 가장 많았다. 내원 시간별로 18-21시에 내원한 환아가 35.6%로 가장 많았다. 3. 주소증을 계통별로 분류해 보면 소화기계 질환이 가장 많았고 신경계 질환이 다음으로 많았다. 영아기에는 신경계 질환이, 유아기, 학동전기, 학동기에는 소화기계 질환이, 사춘기에는 근골격계 질환이 가장 많았다. 4. 발병 후 6시간 이내에 내원한 경우가 48.0%로 가장 많았다. 응급실 내원 전 처치 없이 온 경우가 47.2%, 타 의료기관 진료를 받고 온 경우는 21.8%였다. 응급실에서 수기와 한약 처방을 병행한 경우가 75.2%였으며, 97.3%가 귀가하였다. 결론 : 급성 중증질환보다는 소화불량, 啼哭, 열성경련, 足踝部捻挫 등에 국한되어 한방 응급진료를 선호하는 경향이 있었다. 한방 응급진료의 우수성을 다양한 질환별로 홍보하여 소아 및 보호자의 인식을 개선하고, 자석침, 차침, 灸, 향기요법 등의 다양한 치료방법을 강구하여 응급실에서의 소아 환자 진료를 활성화해야 한다.
한의학
null
kci_detailed_000248.xml
ART001517090
oai_dc
대청룡탕이 지방세포 분화기전에 미치는 영향
The Effects of Daecheongryong-tang on Transcription Factors and Adipogenic Genes during 3T3-L1 Differentiation
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이준문(동의대학교); 조성우(동의대학교); 강경화(동의대학교); 이승연(동의대학교); 유선애(동의대학교)" ]
Objectives: The purpose of this study is to investigate the effects of Daecheongryong-tang (DCRT) on the adipogenesis in 3T3-L1 preadipocytes. Methods: 3T3-L1 preadipocytes were differentiated with adipogenic reagents by incubating for 2 days in the absence or presence of DCRT ranging 0.25 and 2%. The effect of DCRT on adipogenesis was examined by Oil red O staining, and the protein, RNA, and RT-PCR were measured. Results: Our results showed that DCRT decreased the TG content by ORO staining. To elucidate the mechanism of the effects of DCRT on lowering TG content in 3T3-L1 adipocytes, we examined the DCRT modulate expressions of transcription factors to induce adipogenesis and adipogenic genes which is related to the regulation of accumulation of lipids. As a result, the expression of SREBP1, C/EBPβ, C/EBPδ, C/EBPα, and PPARγ genes, which induce the adipose differentiation and adipose-specific aP2, adipsin, LPL, CD36, TGF-β and adiponectin genes which regulates fat formations, were decreased. In addition, DCRT reduced the expression of iNOS and IL-6 in 3T3-L1 adipocytes, resulting in inflammation. Conclusions: DCRT could regulate transcript factor related to induction of adipose differentiation, inhibit the accumulation of lipids and expression of the adipogenic genes.
한의학
null
kci_detailed_000248.xml
ART001517056
oai_dc
性暴力으로 인한 外傷 後 스트레스 障碍 靑少年 1例
A Clinical Report of Post Traumatic Stress Disorder from Sexual Violence
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "최가혜(동서한방병원); 홍상준(동서한방병원 한방소아과); 송인선(동서한방병원)" ]
목적 : 본 증례는 성폭력으로 인한 외상 후 스트레스 장애 청소년 1명을 한방치료하여 유의한 효과를 얻었기에 보고하는 바이다. 방법 : 성폭력 후유증 청소년 1명에게 침치료와 뜸치료를 시행하였다. 결과 : 한방 치료 후 환아 1명은 외상 후 스트레스 장애 증상의 호전을 보였다. 결론 : 이번 증례를 통해 청소년 성폭력 후유증에 대한 한방 치료가 효과적임을 알 수 있었다. 그러나 재발이 가능하므로 지속적인 관찰 및 관리가 필요하며 향후 성폭력 후유증 치료에 대한 더 많은 한방적 연구 및 고찰이 필요할 것으로 사료된다.
한의학
null
kci_detailed_000248.xml
ART001517049
oai_dc
심계 허약아 진단을 위한 절단값의 산정 ; K-CBCL 총문제행동점수를 기준으로
Set the Cut off Values for Diagnosing Heart Weak children ; By Using K-CBCL Total Behavior Problems Score
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "정민정(부산대학교 한방병원 한방소아과); 임정화(부산대학교병원 한방진료처 한방신경정신과); 황보민(부산대학교 한의학전문대학원 한방안이비인후피부과교실); 윤영주(부산대학교); 김기봉(부산대학교)" ]
Objectives:본 연구의 목적은 허약아설문지와 K-CBCL의 상관관계를 알아보는 것이다. 또한 K-CBCL의 총문제행동 점수의 50T를 기준으로 심계허약점수의 절단값을 산정하고자 하였다. Methods:대전 지역 초등학생 271명에게 설문지를 배부하였고, 분석하였다. Results:심계허약점수와 K-CBCL의 총문제행동 점수와 높은 상관관계가 있었다. K-CBCL의 총문제행동 점수의 50T를 기준으로 심계허약점수의 절단값을 산정하고자 하고자 ROC curve를 이용하여 분석하였다. 심계허약아를 진단하기 위한 심계허약점수의 절단값은 남아 11점 여아 8점이었다. Conclusions:심계허약아를 진단하기 위한 심계허약점수의 절단값은 남아 11점 여아 8점이었다.
한의학
null
kci_detailed_000248.xml
ART001517041
oai_dc
한약을 복용한 소아에게 발생한 부작용에 대한 연구
A Study of Side Effects from Korean Herb Medicine on Children
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "정선경(동의대학교 한방소아과); 곡수영(동의대학교 한방소아과); 유선애(동의대학교); 이승연(동의대학교)" ]
목적이 연구의 목적은 한약을 복용한 소아에게 나타난 부작용의 발생률, 부작용의 종류, 부작용과 한약과의 인과관계 등을 조사하고자 하였다. 방법이 연구는 2009년 9월부터 2010년 2월까지 ○○대학교 부속한방병원 한방소아과 외래를 방문한 환아 중 탕약을 복용한 환아를 총 212명을 대상으로 하였다. 환자의 차트리뷰와 전화설문으로 연구하였다. 결과1. 전체 212명 중 부작용이 발생한 경우는 남아 6건, 여아 3건, 총 9건으로 발생율은 4.2%이었다. 2. 가장 많은 빈도의 부작용의 종류는 복통으로 脾계 관련 증상이었다. 3. 부작용은 탕약 복용 1~3일 후 발생했으며, 지속 기간은 탕약 복용 수시간 이내가 가장 많았고, 약의 분복 및 감량으로 대부분 소실되었다. 결론부작용의 증상이 서양의학에서 말하는 약물유해반응으로 말할 정도의 심각한 수준이 아니었다. 가장 빈번한 부작용의 증상은 복통이었다. 후속적인 연구가 필요하다.
한의학
null
kci_detailed_000248.xml
ART001517053
oai_dc
야간 발열을 동반하는 전신형(Systemic type) 소아기 류마티스 관절염(Juvenile Idiopathic Arthritis; JIA) 환아 증례보고
A Case Report of Systemic Type Juvenile Idiopathic Arthritis with Night Fever
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "유창길(유창길한의원); 이윤주(유창길한의원)" ]
목적 : 이 증례보고는 전신형 소아기 류마티스 관절염 환아를 한약치료를 통해 유효한 결과를 얻었음을 보고하는 것이다. 방법 : 전신형 소아기 류마티스 환아에게 한약치료를 적용하였고, 환자의 증상에 따라 양약을 줄여나갔으며, 2~3개월에 한번씩 혈액검사를 하였고, 매일 체온과 전신증상을 전화를 통해 관찰하였다. 결과 : 한방치료를 통하여 환자의 전신형 소아기 류마티스 관절염 증상이 모두 사라졌고, 환아는 모든 항류마티스제를 중단한 상태에서도 좋은 상태를 유지하고 있다. 혈액검사 결과 역시 정상으로 회복되어 임상적 관해 상태에 있다. 결론 : 결과에 의해 한약치료가 전신형 소아기 류마티스 관절염에 효과가 있다는 것을 알 수 있으며, 향후에도 보다 많은 증례를 통한 지속적인 연구가 필요할 것으로 보인다.
한의학
null
kci_detailed_000248.xml
ART001517043
oai_dc
복부 초음파 검사로 진단받은 급성 충수염 환아 증례 보고
A Case Report of Patient with Acute Appendicitis Diagnosed by Abdominal Ultrasonography
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "유수향(동신대학교); 김오영(동신대학교); 채중원(동신대학교)" ]
목적 : 이 연구의 목적은 복부 초음파로 진단 받은 급성 충수염 환아의 한의학적 치료-한약, 침 효과를 밝히기 위함이다. 방법 : 환아는 4일동안 한약치료(가미의이인탕)과 침 치료를 받았으며, 호전을 확인하기 위해 복부 초음파 검사 및 Vas Scale을 사용하였다. 결과 : 우하복부 통증, 오심, 식욕부진 등의 제반 증상이 사라졌으며 복부 초음파 검사 상 정상 소견이었다. 결론 : 이 연구는 4일간의 가미의이인탕 투여와 침치료가 급성 충수염 치료에 효과가 있음을 보여준다.
한의학
null
kci_detailed_000248.xml
ART001444362
oai_dc
紫河車 濕布療法을 이용한 아토피 환자 치험 1례
One Case of Atopic Dematitis Treated by Horminis Placenta External Wet Therapy
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "박은성(경희대학교); 이진용(경희대학교)" ]
Objectives The purpose of this study is to report a Atopic dematitis patient treated by Horminis Placenta external wet therapy. Methods The patient was treated by acupuncture, herb medicine, especially Horminis Placenta external therapy. Kunz type, SCORAD index and Vas scale were used to measure the progression. Results and Conclusions We had evaluated the score during admission. SCORAD index include the extent, the intensity, pruritus, sleeping loss had increased from 52.88 score to 21.26 score. And the symptoms had improved with treatment.
한의학
null
kci_detailed_000248.xml
ART001444359
oai_dc
소아 및 청소년에서 버섯 유두 개수로 산출한 설 미뢰 밀도와 식습관의 상관성 연구
A Study on the Correlation of Fungiform Papillae (Taste Bud) andEating Behavior of Children and Adolescents
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "배선재(압구정함소아한의원); 이상용(잠실함소아한의원); 이은혜(함소아한의원네트워크 연구개발본부); 최현(압구정함소아한의원)" ]
Objectives This study is to find out how fungiform papillae count, which represents the density of taste buds, is related to eating behavior of children and adolescents. Methods The authors measured fungiform papillae count, height, and weight of 50 healthy children aged from 2 to 15. To evaluate the severity of anorexia, parents of the subjects answered modified version of Korean Children’s Eating Behaviour Questionnaire (K-CEBQ). Children with weight of less than 50th percentile were assigned to low-weight group, while the others to high-weight group. Pearson’s correlation test was conducted in order to evaluate the relationship between modified K-CEBQ score and fungiform papillae count. Results Low-weight children scored 29.8±9.1, while high-weight children scored 24.5±7.1. (p<0.05) on modified K-CEBQ. Pearson’s correlation coefficient between modified K-CEBQ score and fungiform papillae count was 0.503 (p<0.05) in low-weight group, 0.260 in high-weight group, and 0.339 (p<0.05) in total. However, there were no statistical significance in correlations between modified K-CEBQ score and percentile of weight, height, or BMI. Conclusions Severity of anorexia was correlated to the density of taste buds, especially in children who weighed less than average. The analysis on each single question indicated that children with high taste bud density had poor appetite not because of their inadequate digestive function, but because of their fastidious eating habit. Further study should be focused on finding out which specific aspect of appetite is related to the taste bud density.
한의학
null
kci_detailed_000248.xml
ART001444367
oai_dc
小兒藥證直訣의 醫案에 나타난 錢乙의 의학사상에 관한 연구
A Study on the Medical Records and Qian Yi(錢乙)‘s Medical Thought in ≪Xiao Er Yao Zheng Zhi Jue≫
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김장현(동국대학교); 황영준(동국대학교); 민상연(동국대학교)" ]
Objectives The Medical record consist of symptoms, the cause of a disease, diagnostic studies, medical treatment, prescription, and so on. Doctors can use medical records as data for diagnosis, treatment, and education. Therefore, medical records are beneficial. Methods Translating ≪Xiao Er Yao Zheng Zhi Jue≫ into modern Korean, and studying the medical records of Qian Yi(錢乙)’s Medical concept in ≪Xiao Er Yao Zheng Zhi Jue≫ were examined. Results Regarding the diagnosis of the pediatric diseases, Si Zhen He Can(四診合參), consider in the eye exam closely. In addition, he closely combined the concept of Wu Zang Bian Zheng(五臟辨證), and diagnosis the pediatric diseases. Wu Zang Bian Zheng(五臟辨證), what Qian-Yi(錢乙) established method was based on Zheng Ti Guan(整體觀) in Huang Di Nei Jing(黃帝內經). Qian Yi(錢乙) took a close look on Chuang Zhen(瘡疹) which had been an inadequate field in those days. He criticized on the habitual misuse of medications. He treated Ji Jing(急驚) and Man Jing(慢驚) separately; Ji Jing(急驚) as Liang Xie(凉瀉) and Man Jing(慢驚) as Wen Bu(溫補). He proposed Zong Gan Zhu Feng and Xin Zhu Jing(縱肝主風, 心主驚) theory and formulated Jing Feng(驚風) theory as well. He emphasized the treatment to Gong Bu Shang Zheng, Bu Bu Zhi Xie, Xiao Bu Jian Shi(攻不傷正, 補不滯邪, 消補兼施) because he had a clear demonstration to Han Re Xu Shi (寒熱虛實) of the five viscera in the field of Fang yao(方藥). Conclusions Understanding ≪Xiao Er Yao Zheng Zhi Jue≫ and its medical records of Qian Yi(錢乙)’s medical concept had quintessential meaning to both modern pediatrician and oriental medical doctors of all medical fields in treating children.
한의학
null
kci_detailed_000248.xml
ART001444366
oai_dc
天麥湯의 알레르기 염증반응 및 기전탐색에 관한 연구
Experimental Study about the Pathway of Inflammatory Allergic Reaction of Cheonmaec-tang
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김원일(동의대학교); 김용현(동의대); 이승연(동의대학교)" ]
Objetives The purpose of this study was to examine the pathway of anti-allergic effects of Cheonmaec-tang (CMT). Methods We examined the cell viability, β-hexosaminidase release, pro-inflammatory cytokines secretion and mRNA expressions, nuclear factor-kappa B (NF-κB) (p65) activation, inbibitor kappa B-alpha (IκB-α) degradation, and MAPKs activation in RBL-2H3 cells pre-treated by CMT of 2.0 ㎎/㎖, 4.0 ㎎/㎖ separately. Results We observed that CMT reduced the secretion of β-hexosaminidase, TNF-α, IL-4 and the expression of COX-2 mRNA in RBL-2H3 cells. Futhermore, CMT inhibited the levels of activation of NF-κB (p65) protein, ERK MAPK, and degradation of IκB-α in RBL-2H3 cells. Conclusoins These results show that CMT has an anti-histamine effect and inhibitory effect of NF-κB (p65) through regulation of IκB-α degradation. These suggest that CMT could be used as an anti-allergic medicine.
한의학
null
kci_detailed_000248.xml
ART001444364
oai_dc
小兒醫方과 東醫寶鑑의 편제와 처방에 대한 연구
Study on Prescription and Formation of SoAEuiBang and DongEuiBoGam
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김초영(경희대학교); 장규태(경희대학교)" ]
Objectives In the later period of Choseon dynasty, korean pediatrics became a pivot part of medicine. SoAUiBang was the most important book in that era. DongEuiBoGam was the most widely read of all oriental medicine books and published in early days of the Choseon dynasty. Therefore, this comparative study on the prescription and formation of SoAUiBang and DongEuiBoGam could be a useful way to understand SoAUiBang's characteristics. Methods This study was based on SoAUiBang and DongEuiBoGam, two literatures of oriental medicine. Results 1. Formation of SoAUiBang had a similar aspect with that of DongEuiBoGam's and enlarged the area of pediatrics by featuring general medical books. However, its formation did not follow the DongEuiBoGam's, but had its unique formation. It tried to include all diseases of pediatrics in the system of DongEuiBoGam. Plus, smallpox and measles belonged to the epidemic diseases were excluded from the area of pediatrics. 2. Comparing SoAUiBang's prescription of some important diseases with DongEuiBoGam's, it was almost a prescription based on DongEuiBoGam's prescription. However, adjustment of herbs and dosages could not be found in any oriental medicine books including DongEuiBoGam. Conclusions SoAUiBang maintained the traditional Oriental medicine based on author’s scholarly creativeness. In addition, it also inherited the lineage of medicine in Korea along with the pedigree of DongEuiBoGam. Therefore, SoAUiBang should be re-evaluated as a medicine book that opened a new field of pediatric and had great academic values.
한의학
null
kci_detailed_000248.xml
ART001444360
oai_dc
아토피樣 피부염 NC/Nga 생쥐에서 消風導赤湯加味와 아토피크림, 紫雲膏 및 消風導赤湯加味의 병용투여가 피부염에 미치는 영향
Effects of SPDJTK (SoPungDoJeokTangKami) and Concurrent Administration of AJ (Atopy cream, Jawoongo) Plus SPDJTK on Atopic Dermatitis-like Skin Lesions in NC/Nga Mouse Induced by BMAC
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김윤희(대전대학교); 한달수(대전대학교); 한재경(대전대학교 한의과대학)" ]
Objectives The purpose of this study is to investigate the effect of SPDJTK(SoPungDoJeokTangKami) and concurrent administration of AJ(Atopy cream, Jawoongo)+SPDJTK on atopic dermatitis-like skin lesions by using in NC/Nga atopic dermatitis mouse induced by BMAC-induced mice. Methods Clinical skin score, hematology and Serum total IgE and IgG1 of NC/Nga atopic dermatitis mice were evaluated. Moreover, the cytokine level, total cell number, Immunohistochemical staining and Histological features of axillary lymph node(ALN), draining lymph node(DLN), peripheral blood mononuclear cells(PBMCs) and dorsal skin tissue were used in NC/Nga mice. Results Orally administrated SPDJTK with concurrent administration of SPDJTK and AJ decreased the clinical skin score, total cell number of WBC, eosinophils in blood, serum total IgE & IgG1, IL-5, IL-13, IFN-γ. Also, total cell number of ALN and dorsal skin tissue, absolute cell number of CD4+, CD8+, CD3+CD69+, CD3+CCR3+, CCR3+, CD4+CXCR5+ in ALN, absolute cell number of CD3+CCR3+, CCR3+ in DLN, granulocytes in PBMCs, activation cell number of CD3+CD69+, CCR3+, total cell number of CD3+ T cell in dorsal skin tissue were significantly decreased. Furthermore, thickness of epidermis, infiltrated inflammatory immune cell and mast cell in dermis, amount of Eotaxin2 mRNA, CCR3 mRNA in dorsal skin tissue, gene expression of IL-5, IL-13 mRNA in ALN, CD4+ Th cell in dorsal skin tissue and CCR3+ eosinophils in ALN were all significantly decreased. However, total number of DLN, absolute number of CD3e+ T cell and CD19+ B cell, absolute number of CD4+, number of Th cell in DLN and gene expressoin of foxp3 mRNA were significantly increased significantly. Conclusions Concurrent administration of SPDJTK and AJ on atopic dermatitis in NC/Nga atopic dermatitis mouse was very effective treatment for atopic dermatitis.
한의학
null
kci_detailed_000248.xml
ART001444369
oai_dc
가미보중익기탕과 가미좌귀음의 폐 섬유화 치료 기전에 대한 예비 연구
The Preliminary Study for Therapeutic Mechanism of Gami-Bojungikgitang and Gami-Jwagwieum for Pulmonary Fibrosis
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이해자(원광대학교); 신권성(원광대학교 한방소아과); 안재선(원광대학교 한의과대학)" ]
Objectives In this study, we evaluated the therapeutic effects of Gami-Bojungikgitang and Gami-Jwagwieum for bleomycin-induced lung fibrosis in mice. Methods Extracted lyophilization, Gami-Bojungikgitang (96g) and Gami-Jwagwieum (118g) boiled, filtered, depressed, concentrated, and are obtained. They were divided into five groups: normal, group IA; Animal group treated with bleomycin observed on the 21th day, group IB; Animal group treated with bleomycin observed on the 42th day, group IIA; Animal group treated with bleomycin and Gami-Bojungikgitang. Gami-Jwagwieum observed on the 21th day, group IIB; Animal group treated with bleomycin and Gami-Bojungikgitang/Gami-Jwagwieum observed on the 42th day. Mice are used on the 42th day and as a result, bronchoalveolar lavages fluid is obtained. Counting total number of cells, different ratio of macrophage, lymphocyte, and neutrophil are established. Results In animal group treated with bleomycin and Gami-Bojungikgitang, total cell count decreased by 50% in 3 weeks compared to animal group with non-administrated Gami-Bojungikgitang. However, total cell count in 6 weeks increased compared to 3 weeks although total cell count still decreased compared to animal group with non-administrated Gami-Bojungikgitang. In the view of differential cell counts in bronchoalveolar lavages fluid in treatment group on 3 and 6 weeks, neutrophile was a few and lymphocyte decreased. In animal group treated with bleomycin and Gami-Jwagwieum, total cell count decreased by 50% in 3 and 6 weeks compared to animal group with non-administrated Gami-Jwagwieum. In the view of differential cell counts in bronchoalveolar lavages fluid in treatment group on 3 and 6 weeks, lymphocyte also decreased. Conclusions Gami-Bojungikgitang and especially Gami-Jwagwieum for bleomycin-induced lung fibrosis in mice were effective in total cell count and differential cell count.
한의학
null
kci_detailed_000248.xml
ART001444368
oai_dc
六味地黃湯加味方 약침이 연골세포에 미치는 영향
Effect of Yukmijihwang-Tang Gamibang Aqua-acupuncture on the Recovery of Chondrocyte Phenotype
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김장현(동국대학교); 최원주(동국대학교 한의과대학 소아과학교실); 민상연(동국대학교)" ]
Objectives The purpose of this study is to examine the effect of chondrocyte re-differentiation in using ukmijihwang-Tang gamibang aqua-acupuncture. Methods In this study, chondrocytes were extracted from New Zealand white rabbit's knee joint, and cultured in monolayer after collagenase treatment. In the third passage, after the mRNA transcript of the type II collagen significantly reduced, diluted Yukmijihwang-Tang gamibang were added to cultured of chondrocyte, and its effect on the mRNA expression of type II collagen was quantitatively evaluated. Results As a result of treatment with Yukmijihwang-Tang gamibang in vitro for 48 hours, the mRNA expression of type Ⅱ collagen was up-regulated. In addition, the result of H&E-staining in vivo indicated that chondrocyte-like tissues were formed in repairing injured cartilages after 12 weeks of treatment with Yukmijihwang-Tang gamibang. Conclusions These results indicated that Yukmijihwang-Tang gamibang was effective on the recovery of chondrocyte phenotype, and could be used for cartilage regeneration in arthritic diseases. However, more clinical study of Oriental medical treatment for this case might be also needed.
한의학
null
kci_detailed_000248.xml
ART001444361
oai_dc
소아 성장을 위한 한약투여에 대한 만족도와 기대치 조사
A Study for Satisfaction and Expectation of Effect on the Growth of Children Treated with Herbal Medicine
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "박은성(경희대학교); 이진용(경희대학교); 김덕곤(경희대학교)" ]
Objectives The purpose of this study is to evaluate the effect of herbal medicine in children's growth and to report the children's expectation. Methods 171 children visited the department of Pediatrics, Kyung-Hee Oriental Medical Hospital from June 2009 to Desember 2009 were studied. They were treated more than 6 months and they visited our clinic more than 3 times. Every time when patients visited our hospital, their height, body weight and obesity degree was examined using DS-102(dszenix, Seoul). Also, height percentile of first and the last visit was measured, and those were compared by the Growth Statistics Curve made by the Korean Association of Pediatrics, 2007. Results and Conclusions The mean growth of total children increased by 4.42 percent; the increased percent for boys was 4.17 and that of girls was 5.00. Herbal medical treatment helped growth in children who took medicine for growth retardation problem. Plus, majority of parents who visited the department of Pediatrics, Oriental Medical Hospital satisfied with the service and their children’s height. Although thinking genetic factor is important for their height, but they think that herbal medical treatment help the growth with changing eating habit.
한의학
null
kci_detailed_000248.xml
ART001444365
oai_dc
중학생 비만아들의 생활습관과 정신상태의 상관관계
The Realationship between Life Style of Obesity Teenager and Mental Condition
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김덕곤(경희대학교)" ]
Objectives The relationship between depression, obesity, life style of adolescents has been reported, but the results were not consistent. Thus this study was designed to find out the relationship. Methods The participants were the first and second grade middle school students. The participants were asked to measure their height and weight etc, and were asked to survey questionnaires. To diagnose the students' degree of depression, Children's Depression Inventory(CDI) by Kovas and Beck. Results The average depression score in the obese group was significantly higher than that of the normal body weight group. In addition, male obese group scored higher on CDI than the female obese group, and the obese group of participants who don't exercise, but like to play computer games and watch TV scored higher on CDI than the group who exercise and don't play computer games. Conclusions This study proved that depression in adolescent was closely related with obesity and obesity-related lifestyles. “The research was supported by the Kyung Hee University Research Fund in 2007”(KHU-20071638)
한의학
null
kci_detailed_000248.xml
ART001444363
oai_dc
항류마티스제(DMARDs)와 비스테로이드성 소염진통제(NSAIDs)에 반응하지 않는 다수관절형 소아기 류마티스 관절염 환아 증례 보고
A Case Report of Polyarticular Type Juvenile Idiopathic Arthritis(JIA) Patient Ineffective Response to DMARDs and NSAIDs
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "유창길(유창길한의원); 이윤주(유창길한의원)" ]
Objectives This study is to examine case that has an significant result on treating Polyarticular Type Juvenile Idiopathic Arthritis(JIA) the patient who did not response to DMARDs and NSAIDs with oriental medicine. JIA is the most common form of persistent arthritis in children before age 16. The symptoms of JIA is pain and edema of joints, fever, lethargy, reduced physical activity, and poor appetite. But the symptoms vary. Methods The patient felt pain and had limitation of mobility on his joints, but the DMARDs and NSAIDs were not effective. Therefore, he was treated with oriental medicine and withdrew from DMARDs and NSAIDs. The patient took DMARDs and NSAIDs from May 2007 to November 2008(He did not took DMARDs and NSAIDs from December 2007 to June 2008), and took oriental medicine from November 2008 until now. Results The patient's pain and limited mobility on his joints, edema, morning stiffness, fatigue was gone, and could maintain the condition. He doesn't have DMARDs or any other western medicine anymore. Conclusions This study shows that a Polyarticular Type Juvenile Idiopathic Arthritis patient who had ineffective response to DMARDs and NSAIDs can reach to the clinical remission by oriental medicine treatment. His morning stiffness, fatigue, pain of joints, edema was gone and ESR was in normal range with Oriental medicine treatment.
한의학
null
kci_detailed_000248.xml
ART001477894
oai_dc
PubMed를 통한 소아질환에 대한 추나 치료 연구의 최신 동향
The Latest Trends of Chiropractic Treatment on Pediatric Disease
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "조성우(동의대학교)" ]
Objectives We aimed reviewing studies related to the treatment of children by Chiropractic treatment. Methods We referred to PubMed by using searching keywords of chiropractic and the terms of pediatrics, such as child, children, juvenile, pediatric, infant. Twenty four papers were found. Results 1. We found twenty four papers about pediatric and chiropractic. 2. Chiropractic was used in various pediatric diseases and was shown to be effective. 3. There were several views on safety and effectiveness of pediatric chiropractic. Conclusions Applying of pediatric chiropractic was broad, and it was effectively cure for pediatric diseases.
한의학
null
kci_detailed_000248.xml
ART001477886
oai_dc
삼복첩을 이용한 동병하치법에 관한 임상연구고찰
Clinical Trial Study about Preventing Winter Diseases through Summer Prophylactic Treatment Using Acupoint Sticking
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "성현경(동국대학교 한방소아과); 민상연(동국대학교); 김장현(동국대학교)" ]
Objectives The purpose of this study is to analyzing clinical trials of the current acupoint sticking treatment on Sambok* to prevent winter diseases through summer prophylactic treatment. Methods 33 Chinese clinical studies published in last fifteen years were selected for analysis. Results Acupoint sticking treatment on Sambok* is used in asthma, rhinitis, bronchitis. Commonly used herbs are Sinapis Semen(白芥子), Asari Herba Cum Radix(細辛), Euphorbiae Kansui Radix(甘遂), Corydalis Tuber(玄胡索), Moschi Moschus(麝香), Ephedrae Herba(麻黃), Cinnamomi Cortex Spissus(肉桂) and Commonly used acupoints are Feishu(肺兪), Kohwang(膏肓), Shinsu(腎兪), Pisu(脾兪). 33 studies showed that the effect of treatment in different age, symptom, acupoints, herbs, methods. However, it shows that acupoint sticking treatment on Sambok* is effective in various diseases, especially in respiratory disease. Conclusions This study shows that acupoint sticking treatment on Sambok* is effective in preventing many diseases. More clinical studies about acupoint sticking treatment and standardizations to evaluate effectiveness are needed to prove its efficacy clearly.
한의학
null
kci_detailed_000248.xml
ART001477889
oai_dc
肺系虛弱兒에 대한 加減保肺養營煎의 임상적 효능 연구
Effects of the Gagam-Bopyeyangyeongjeon on the Lung Weakness Children(肺系虛弱兒)
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "곡수영(동의대학교 한방소아과); 정선경(동의대학교 동의의료원 한방소아과); 유선애(동의대학교); 이승연(동의대학교)" ]
Objectives The purpose of this study is to evaluate the clinical effectiveness and prophylactic treatment effectiveness of Gagam-Bopyeyangyeongjeon(GGBYJ) on the Lung Weakness Children(肺系虛弱兒) who catch cold easily. Methods The study has been carried out from 27 children, who were treated with GGBYJ in Department of Pediatrics, Oriental Medical Hospital from August to December in 2009. The study was completed through patient chart review and telephone survey. Results 1. Immediately after the treatment, there was significantly decreasing(p=0.005) on respiratory symptoms in the Lung Weakness Children(肺系虛弱兒) who catch cold easily. 2. After the treatment, when season changes (three months later), there were preventive and continuous effects on reducing morbidity and on decreasing degree of symptoms against new respiratory infections compared to the previous year before taking medicine. 3. GGBYJ improved the respiratory symptoms, and also anorexia, constipation, heights, skin and fatigue. Conclusions In conclusion, there were significant clinical and preventive effectiveness of GGBYJ for the Lung Weakness Children(肺系虛弱兒) who caught a cold easily. Further studies are needed with more clinical cases.
한의학
null
kci_detailed_000248.xml
ART001477861
oai_dc
五遲 五軟 五硬 幼兒의 임상면접지 분석
Analysis of Clinical Questionnaire on the Five Retardation, Five Stiffness and Five Limpness
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "백은경(해마한의원); 박재형(해마한의원); 윤영주(부산대학교); 박재현(강북한방병원)" ]
Objectives Taking detailed patient history helps earlier diagnosis and treatment of developmental disability. In this study we analyzed the clinical questionnaire to find out the clinical characteristics of those with five-retardation, five-limpness, or five-stiffness. Methods The data was collected from 484 children under the age of six who have visited H oriental medicine clinic for developmental delay. The clinical questionnaire was filled out by their parents and the data was analyzed statistically. Results 436 children showed symptoms of five-retardation, 90 children suffered from five-stiffness, 54 children showed five-limpness and 7 children suffered from five-stiffness and five-limpness complex. Generally, boys had higher chance to show disease symptoms than the girls (2.32:1) and 40 children (8.26%) reported family history of developmental disability. Cerebral palsy ranks the most common familial disease, followed by developmental delay, mental retardation, autistic disorder and language disorder. Among the children we have studied, 285 children (63.19%) showed delayed unassisted walk while 192 children (42.57%) had language disorder. Also, 138 children (28.51%) had both walk and language disorders. The children in this study also showed delayed toilet training and half of them had little stranger anxiety when they were infants. It was also found that 120 children (24.79%) experienced epilepsy. This study reaffirmed that low birth weight, premature birth, and suffocation are major risks causing neurological damage. Conclusions They had history which including family history, problems at birth, epilepsy, face recognition, muscle tone disorder, delayed walking without assistance, language ability, and toilet training.
한의학
null
kci_detailed_000248.xml
ART001477876
oai_dc
수도권 지역 초등학생의 건강기능식품 및 한약 복용 실태에 대한 연구
The Study on Consumption of Health Supplements and Herbal Medicines by Elementary School Students in Gyeonggi-do
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김미기(원광대학교 한방소아과); 정지호(원광대학교); 신권성(원광대학교 한방소아과); 이동엽(원광대학교 한의학전문대학원); 이해자(원광대학교); 박은정(원광대학교)" ]
Objectives The purpose of this study is to get the basic information about the actual amount of consumption of the Health supplements and Herbal Medicines. Also, we investigated the consumption differences according to the regions. Methods 500 questionnaires were handed out to parents of elementary students in O O, Gyeonggi-do province, and 331 questionnaires were collected and evaluated for this study. Results Among the 331 students, 58.4% were female, and 41.6% were male. The percentages of the subjects consuming health supplements and herbal medicines were 67.4% and 59.2% respectively. The maximum period of taking the health supplements were from 1 month to 6 month (49.5%), and the maximum period of taking the herbal medicine was within one month (55.6%). The total cost of the health supplements was less than 100,000won (43.7%), which was the most common while herbal medicine cost was between 100,000won and 200,000won (40.6%). The most common age of consuming the health supplements and herbal medicine for the first time was six to ten years old (47.3%); the case of herbal medicine was one to six years old (64.0%). Most of people purchased health supplements from pharmacy (48.0%), and purchased the herbal medicine from the oriental medical clinic (61.8%). Among those people who purchased health supplements, they bought nutritional supplements (82.8%), red ginseng or ginseng products (43.4%), plum extract products (10.9%), and chlorella products (6.8%). The reason for consuming health supplements was to be healthier even though there is no ongoing illness (47.1%), which was the most common reason. The reason for consuming herbal medicine was to cure weakness (39.3%). For the responses about effectiveness after taking medications, people thought herbal medicine seemed to be more effective compare to health supplements (72.3%, 63% respectively). Only 1.4% of the subjects consuming the health supplements showed adverse effects while herbal medicine showed 4.6%. The most common adverse effects were 'general reaction' caused by the health supplements and dermatologic problems caused by the herbal medications. Conclusions Among 331 subjects, the percentage of consuming the health supplements (67.4%) was higher than the Herbal Medicine (59.2%). The total consuming cost of the herbal medications was higher than general health supplements. Also, the maximum period of consuming the health supplements was longer than herbal medications. Therefore, it is shown that herbal medications have no price competitiveness compare to health supplements. The age of using the herbal medicine for the first time was younger than the health supplements. Even though many people can purchase both health supplements and herbal medication from pharmacies and local oriental medical clinic, it is also shown that some people thought that the health supplements should be purchased from oriental medical hospital (13.9%). The most commonly taken forms of the health supplement was nutrition-supplying products, and the second common health supplements were ginseng and red ginseng. The health supplements were commonly consumed for preventing illness and for maintaining healthy life rather than for cure diseases. On the other hand, the herbal medicine was more commonly consumed to be taller or to treat diseases. More than half of the entire people replied as 'satisfied' for their purchase. Some adverse effects and general reaction were common with the subjects consuming health supplements while dermatological adverse reaction was common with the subjects consuming herbal medications.
한의학
null
kci_detailed_000248.xml
ART001477891
oai_dc
우리나라 양산지역 학동전기 아동에서 비만 진단을 위한 체지방률의 절단값
The Cut Off Values of Body Fat Percentage for Diagnose Obese among Selected Number of Preschool Children in Yangsan
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "정민정(부산대학교 한방병원 한방소아과); 김기봉(부산대학교)" ]
Objectives The objectives of this study were to evaluate the correlations between the indices of obesity and percentage body fat by bioelectrical impedance analysis(BIA). Also, this study was designed to define the cut off values of percentage body fat by BIA which would represent BMI and degree of obesity in order to detect overweight and obesity in preschool children. Methods The height and weight of 683 children aged four to six years old were measured. Also, percentages of body fat were measured by BIA. Results There were high correlations between the boy's body fat percentages and degree of obesity(r=790). Also, there were high correlations between the girl's body fatpercentages and BMI(r=778). The cut off values of body fat percentage, which would correspond to those of BMI percentiles, were calculated by ROC curve analysis. To classify as an overweight, the correspondent cut off values of body fat percentage were 19.55% in boys and 22.35% in girls. For obesity, the cut off values were 28.80% in boys and 27.60% in girls. The cut off values of body fat percentage, which would correspond to degree of obesity were calculated by ROC curve analysis. To classify as an overweight, the correspondent cut off values of body fat percentage were 19.75% in boys and 22.35% in girls. For obesity, the cut off values were 29.05% in boys and 28.75% in girls. Conclusions According to the BMI criteria by the Korean pediatrics society in 2007, the most appropriate cut off values of body fat percentage in for four to six years old children were follows; for boys, 19.55% considered as overweight, and 28.80% as obese while for girls, 22.35% considered as overweight and 27.60% as obese. According to suggested degree of obesity criteria, the most appropriate cut off values of body fat percentage in for four to six old children were were follows; For boys, 19.75% was considered as overweight, and 29.05% as obesity. For girls, 22.35% was considered as overweight, and 28.75% as obese.
한의학
null
kci_detailed_000248.xml
ART001477892
oai_dc
성동구내 어린이집 어린이의 알레르기 질환과 허약아의 실태 및 관련성에 대한 보고
The Relationships between Allergy and Weakness in Children in Seong-Dong District
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "박유진(제인한방병원); 윤지연(제인한방병원 소아과); 명성민(중원대학교)" ]
Objectives The purpose of this study is to find the relationships between the allergy and weakness in children in Seong-Dong district. Methods 802 day care centers children were participated for survey on allergic disease, risk factors, and weakness. From the result, we analyzed the relationships between the aforementioned factors. Results 1. 802 children were participated for the survey. We eliminated survey answers with unclear answers, and selected 792 survey sheets as our final subject of study. The age of majority of subjects(720 children) were between one to six years old, and the others were under the age of one and over seven. 2. The prevalence rate of asthma in a lifetime was 6.69%, allergic rhinitis was 14.87%, atopic dermatitis was 28.82%, allergic conjunctivitis was 6.29%, food allergies was 9.58%, and drug allergies was 1.4%. In 2009, the prevalence rate of allergies during treatments is 6.69% for asthma, 13.41% for allergic rhinitis, 13.64% for atopic dermatitis, 4.13% for allergic conjunctivitis, 5.23% for food allergies, 0.96% for drug allergies. 3. The significant risk factors were types of dwelling, pet with fur, dirty environments without vacuum cleaners, the numbers of times bed covers were washed, frequency of air ventilation, changes in body after moving, family history. 4. The distribution of the number of children with weakness within the five visceras were respiratory weakness, digestive weakness, psychoneurologic weakness, neuromotor weakness, and urogenital weakness in the order of most to the least. More specifically, children who only has respiratory weakness were the majority, while children who have respiratory and digestive weaknesses, children who have respiratory, digestive, and psychoneurologic weaknesses, children who have respiratory and psychoneurologic were followed. 5. With the exception of children with urogenital weakness, Most of the children with respiratory weakness, digestive weakness, psychoneurologic weakness, and neuromotor weakness had been treated for allergies in 2009, while children who were diagnosed with allergic diseases at least once in their lifetime most likely had weak respiratory, digestive or psychoneurologic systems. Conclusions The results of this study showed that there was a correlation between children with weak viscera and children with allergic diseases. However, further research would be necessary.
한의학
null
kci_detailed_000248.xml
ART001477896
oai_dc
關元(CV4)에 溫筒灸를 시술한 夜尿 患兒 5례 보고
The Five Cases Report about Enuretic Children with Moxa Bucket Moxibustion on Gwanwon(CV4)
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김지영(춘천한방병원 한방내과); 임해원(춘천한방병원); 김지현(춘천한방병원 한방안이비인후피부과); 권강(춘천한방병원 한방안이비인후피부과); 김종화(춘천한방병원 한방내과)" ]
Objectives This study to investigate the effect of oriental medical treatment including moxa bucket moxibustion on children with nocturnal enuresis. Methods We treated five cases of enuretic children with oriental medical treatment like moxa bucket moxibustion on Gwanwon(CV4) at every cases and acupuncture, TDP, herbal medicine at some cases. To investigate relapse, we followed up by telephone at least about 3 months after the end of the therapy. Results After the treatment, the number of enuresis before and after the treatment were compared. The number was decreased by 67% or more all cases. Conclusions According to the result, oriental medical treatment including moxa bucket moxibustion is considered to be effective on the nocturnal enuresis and further study is needed with more cases.
한의학
null
kci_detailed_000248.xml
ART001477880
oai_dc
소아 청소년의 고혈압에 영향을 미치는 요인
Factors Influencing Hypertension in Children and Adolescents
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "조민서(대전대학교 천안한방병원 한방소아과); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]
Objectives This study was performed to investigate the effects of obesity, food, physical activity and stress on blood pressure changes for children and for adolescents. Methods The participants were the first and the fourth grade elementary school students and the first grade of middle school students. They were asked to measure the blood pressure, height, weight and were asked to complete questionnaires. Results The systolic and diastolic blood pressure of male was significantly higher than that of female and the prevalence of hypertension among the first and the fourth grade elementary school students and the first grade of middle school students were 15.6%, 13.6%, and 7.8%, respectively. Height, weight and body mass index (BMI) were highly correlated with the level of blood pressure. However, food, and physical activity, stress and depression were poorly correlated with the level of blood pressure. Conclusions This study proved that blood pressures in children and in adolescent were closely related with obesity, sex, and height.
한의학
null
kci_detailed_000248.xml
ART001477895
oai_dc
저체중 소아의 성장과 골성숙도에 관한 임상적 연구
A Study on the Growth, Skeletal Maturity of Chidren with Low Weight
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김초영(경희대학교); 장규태(경희대학교)" ]
Objectives The study was designed to find out the relationships between low weight and growth, skeletal maturity among children by analyzing body composition and bone age. Methods Subjects were composed of 336 children from six years to seventeen years of age, without any other diseases related to growth, who visited the department of oriental pediatrics East West Neo Medical Center at Kyung Hee University and were measured their body composition and bone age. Results There were significant correlations between decreasing of RH-MPH(%) and low weight. 1. As obesity index decreased, the RH-MPH was also decreased. 2. The RH-MPH(%) of the low weight group according to the obesity index classification was significantly decreased than that of the normal weight group. 3. The skeletal maturity was more decreased in the low weight group. However, the differences between the two group was not significant. 4. The RH-MPH(%) was increased in children who developed secondary sexual character. Skeletal maturity was decreased in children who developed secondary sexual character. 5. The RH-MPH(%), and skeletal maturity was not significantly different between males and females. 6. Only in the case of children without development of secondary sexual character, low weight caused significant RH-MPH(%) decrease. Conclusions Low weight children might be smaller than what it supposed to be. Also, low weight could affect body development more to the children than to the teenager.
한의학
null
kci_detailed_000248.xml
ART001477893
oai_dc
木瓜 추출물이 항알레르기 및 항산화 작용에 미치는 영향
The Antiallergic and Antioxidative Effects of Chaenomeles Sinensis (CS) in RBL 2H3 Cells
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이승연(동의대학교)" ]
Objectives The purpose of this study was to investigate the antiallergic and antioxidative effects of Chaenomeles Sinensis (CS). Methods CS pretreatments inhibited anti-DNP IgE in RBL-2H3 mast cells for an hour. we measured cell viability, -hexosaminidase release, IL-4, TNF- secretion, and IL-4, TNF- mRNA expression CS pretreatments inhibited DNP-HSA() for ten minutes, we measured Dicholrodihydrofluorescein(DCF) and DPPH radical-scavenging activity in 0.5 mM 1,1-diphenyl-2-picrydrazyl(DPPH) radical solution, 0.1ml, 99% ethanol 0.8ml, and CS 0.1 ml mixed solution. Results 0, 1, 2, 3, 4, 5 mg/ml CS treatments were not affect on cell viability and inhibited b-hexosaminidase release, IL-4, TNF- secretion, CS treatments also decreased IL-4, TNF- mRNA expression in RBL-2H3 cells. CS treatments inhibited reactive oxygen species(ROS) and DPPH radical-scavenging activity. Conclusions These results suggest that CS may be useful for the prevention or treatment of allergic disease.
한의학
null
kci_detailed_000248.xml
ART001477864
oai_dc
한방병원 산후조리센터 산모를 대상으로 한 모유수유 실태 및 인식조사
A Survey on Understanding and Actual Condition of Breast-feeding of Woman at Oriental Medicine Hospital Postpartum Care Center
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "정지호(원광대학교); 김미기(원광대학교 한방소아과); 박진수(원광대학교 한의과대학 침구과학교실); 신권성(원광대학교 한방소아과); 박은정(원광대학교)" ]
at Jeonju Wonkwang University Oriental Medicine hospital postpartum care center. Results The majority of women(79.2%) had planned breast-feeding. However, only 32.1% of women currently have fed breast-feeding. 58% of mothers who did partial breast-feeding and breast-feeding currently have planned to breast-feed more than 7 months. The main reason of bottle-fed is concern of insufficient amount of breast milk(72.2%). Also the main reason of breast-feeding is good for baby's health(90%). The average score on the test of the understanding about the methods and advantages of breast-feeding was out of total 18.49.1% of women thought that taking herbal medicine would affect baby during breast-feeding. Also 71.7% of women thought that herbal treatments (acupuncture, herbal medicine) would be helpful when the amount of breast milk is insufficient. Conclusions This survey has showed that in spite of full breast-feeding plan, the percentage of actual breast-feeding rate is low. Timely education is needed to increase breast-feeding rate. It is worth to consider herbal treatment to increase breast milk amount. In addition to that it is necessary to create a hospital environment in which mothers can easily begin breast-feeding as soon as possible after delivery. Moreover, beyond the medical field, political and social supports for breast-feeding are needed.
한의학
null
kci_detailed_000248.xml
ART001477887
oai_dc
소아·청소년 구취 환자의 임상적 특징에 대한 연구
A Clinical Study on Characteristics of Pediatric Patients with Halitosis
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "윤혜준(경희대학교 한의과대학 소아과학교실); 이진용(경희대학교)" ]
Objectives Halitosis affects a large proportion of the population, and it may cause a significant social or psychological problems but pathophysiological mechanism of halitosis is unclear. The purpose of this study is to investigate pediatric halitosis patients' characteristics and their related symptoms. Methods 133 patients were participated at the Pediatric Clinic of Kyanhee Oriental Medical Center from May 29th, 2010 to July 10th, 2010. We measured sulfide level and reviewed medical charts and asked some questions. Patients of sex, age, respiratory symptoms, digestive symptoms, systemic symptoms and sulfide level were analyzed. Results Stuffy nose, cough after sleep, sputum, snoring, indigestion, stomachache, motion sickness, and Bi-We-Soo diagnosis grades were significantly associated with halitosis Conclusions Based on data, we found that halitosis is related to the respiratory and digestive symptoms. Also, we can refer this study when diagnosing patients or giving treatments to patients.
한의학
null
kci_detailed_000248.xml
ART001477872
oai_dc
성인 비만과 비교를 통한 소아 비만의 특성 연구-천안 지역 중심으로
A Study on Characteristics of Obesity in Young Age and Comparison of Obesity in Adults in Cheon-an
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "서희연(대전대학교 한방소아과); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]
Objectives The recent prevalence rate of obesity in children is increasing, but so far the majority of ongoing research is focused on obesity in adults. Even comparison studies between obesity in adults and in children are insufficient at this stage. Thus, our research will investigate the characteristics of obesity in children based on the comparison with adults. Methods The blood levels including glucose, cholesterol, AST, ALT of obese children and obese adults were compared and analyzed. Results From comparison studies, the levels of glucose, cholesterol, ALT in adults were higher than in children. In order to take account the age differences, only the rate of abnormal levels based on the reference range were compared. As a result, the abnormal rate in blood cholesterol level was higher in children. Conclusions Childhood obesity may develop complications at early age and has high potential risk to result in adult obesity as well. Therefore, child obesity needs to be treated with more caution and careful attention.
한의학
null
kci_detailed_000248.xml
ART001477867
oai_dc
食癎으로 진단된 癎疾 患兒 2例에 대한 證例報告
Two Cases Report of Epileptic Children Diagnosed as Sik-Gan(食癎)
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "손미주(대전대학교 한방소아과); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]
Objectives The purpose of this study is to report two cases of epileptic children who were diagnosed as Sik-Gan(食癎) and were treated by oriental medical treatment. Methods We diagnosed the patients as Sik-Gan(食癎) and treated them with herbal medicine, acupuncture, moxa and oriental physical therapy. We observed the improvement of patient's disease by checking seizure frequency and clinical progression of gastrointestinal symptoms. Results Oriental medical treatment reduced patients' the number of seizures, and improved gastrointestinal symptoms. Conclusions This study showed that the oriental medicine can be a meaningful treatment for epileptic children who were diagnosed as Sik-Gan(食癎), but more relevant studies on epileptic children diagnosed as Sik-Gan(食癎) are needed.
한의학
null
kci_detailed_000248.xml
ART001412251
oai_dc
초등학생의 건강기능식품 및 한약 복용 실태에 대한 연구
A Study on the State of Health Functional Foods & Herbal Medicine Consumed by Elementary School Students
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김미기(원광대학교); 정지호(원광대학교); 이해자(원광대학교); 안민섭(원광대학교); 박진수(원광대학교); 박은정(원광대학교); 안재선(원광대학교); 임정훈(원광대학교)" ]
Objectives The purpose of this study is to get the basic information from patients how much they understood about their medication and also to know whether patients are making reasonable drug choice between Health Functional Foods and Herbal medicine. Methods 500 questionnaires were handed out to the parents of students in two elementaryschools located in ○○, Junlabukdo province. 421 questionnaires were completed to be evaluated. Results Among 421 subjects, 53.0% were female, and 47.0% were male. The percentages of the subjects consuming Health Functional Foods and herbal medicine were67.7% and 67.8%, respectively. Among those people who consumed Health Functional Food, 44.1% were using nutritional supplements, red ginseng or ginseng products (26.9%), chlorella products (11.5%), and plum extract products (7.7%). As for the reason to consume Health Functional Foods were varied, but "in order to be healthy, although currently displaying no illness.'(43.0%) were the most responses among the given choices. On the other hand, the reason for consuming herbal medicine was 'In order to grow taller'(26.1%), 'Inorder to cure weak physical state frequently displaying common illnesses',(25.9%), and 'In order to cure diseases.'(23.3%). For the questions about effectiveness after consumption,the 69.9% subjects said that it seemed to be effected, and that % was slightly higher than that of subjects with consuming Health Functional Foods(64.4%). For question concerning preferences between Health Functional Foods and herbal medicine, 57.5% chose herbal medicine, and this percentage was higher than that of Health Functional Foods(42.5%). As for the reasons of additional consumption of the Health Functional Foods, subject answered as 'Easy to consume.'(41,6%), which was the most common among the subjects consuming Health Functional Foods. On other hand, the subjects of herbal medicine answered as that herbal medicine is 'more effective'(45.7%), and 'more trustworthy in preventing side-effects.'(40.3%). After consumption of the herbal medication, only 3.9% of the subjects consuming either Health Functional Foods or herbal medicine hadside-effects. The most common side-effects were 'dermal reaction' which is normally caused by Health Functional Foods and 'indigestion' problems caused by herbal consumption. Conclusions According to the 421 subjectsthose involved in study, the percentages of consuming Health Functional Foods(67.7%) and herbal medicine(67.8%) were similar. The most commonly consumed products were a type of Health Functional Foods which were the nutrition-supplying products. Ginseng or red ginseng products were the next commonly used products. Health Functional Foods were commonly consumed for preventing illness and maintaining health rather than any other purpose. In contrary, herbal medicines were more commonly consumed for purposes such as for growth or treating certain type of disease. As a result of consumption, more than half of both subject replied as 'satisfied'. As for the side effects, dermal reaction was the most common problem for those with consuming Health Functional Foods, while indigestion was the most common side effect from the subjects with consuming herbal medicine.
한의학
null
kci_detailed_000248.xml
ART001412272
oai_dc
오과다가 쥐의 폐섬유화 모델의 치료에 미치는 영향
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이해자(원광대학교)" ]
한의학
null
kci_detailed_000248.xml
ART001412243
oai_dc
韓方病院 小兒科 入院 患者의 主訴證에 대한 硏究
An Observation of the Chief Complaints of Padiatric Inpatients in the Oriental Hospital
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "천진홍(동국대학교); 김기봉(부산대학교); 민상연(동국대학교); 김장현(동국대학교); 유현영(동국대학교)" ]
Objectives The purpose of this study is to collect the statistics of pediatric problems and to develop more effective oriental medical treatments for pediatric diseases, their clinical applicability, and chief complaints on pediatric inpatients in oriental hospitals. Methods The study was composed of seventy inpatients thatwere age from 0 to 20, had received hospital treatment at the pediatrics in Dongguk Bun-Dang Oriental Medicine Hospital for seven years from 1 January 2002 to 31 December 2008. The chief complaints were mainly categorized by oral examination on their patients. Results 1. In this study, male children were thirty one and female children were 39. Thus, sex ration of male to female was 0.79:1. 2. In age distribution, one month to one year were three (4.3%), 1 to six years were forty two (60%), six to ten years were fifteen (21.4%), and ten to twenty years were ten (14.3%) 3. In November, the number of inpatients was the highest (15.7%) in a year. However, there were no significant seasonal differences. 4. In the systemic division, the respiratory diseases : 44(62.9%), the digestive diseases : 11(15.7%), the infectious diseases : 5(7.1%), the musculoskeletal diseases : 3(4.3%), the diseases of nervous system : 3(4.3%), the gynecologic diseases : 1(1.4%), the liver and biliary disorders : 1(1.4%), and etc. : 3(4.3%). 5. The chief complaint of the inpatients is pneumonia, a common cold, respiratory complex symptoms, rhinitis, sinusitis, bronchitis, tonsillitis, diarrhea and etc. Conclusions The two main causes of inpatients were respiratory diseases and digestive disease. More data of inpatients are required for further study. Thus, the new diseases and treatment methods should be studied as a field of oriental medical treatment.
한의학
null
kci_detailed_000248.xml
ART001412239
oai_dc
주의력 간섭검사와 허약아 증상에 관한 연구- 스트룹 아동 색상-단어검사 중심으로-
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "곡수영(동의대학교 한방소아과); 유선애(동의대학교); 이승연(동의대학교)" ]
한의학
null
kci_detailed_000248.xml
ART001408920
oai_dc
아토피樣 피부염 NC/Nga 생쥐에서 滋陰除濕湯加減과 아토피 크림-紫雲膏의 병용투여가 피부염에 미치는 영향
Effects of Concurrent Administration of JaUmJeSeupTangKaKam(JUJSTK) and Atopy Cream, Jawoongo(AJ) on Atopic Dermatitis-like Skin Lesions in NC/Nga Mouse
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이남열(대전대학교); 김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives The purpose of this study is to examine the effect of a concurrent administration of JUJSTK and AJ on atopic dermatitis in an in-vivo experiment. Thus, this study is expressed by using NC/Nga atopic dermatitis mice which have histological and clinical similarities to that of humans have been used. Methods Clinical skin score, hematology, serum total IgE and IgG1 of the mouse was evaluated, and cytokine levels, total number of the cells, immunohistochemical staining, histological features of axillary lymph node(ALN), peripheral blood mononuclear cells(PBMCs), and a dorsal skin tissue of the mouse were analyzed. Results Oral administration of JUJSTK and concurrent administration of JUJSTK and AJ lowered the clinical skin score, total cell number of WBC, eosinophils in blood, and serum total of IgE & IgG1, IFN-γ, IL-5, IL-13, IL-17. In addition, total cell number of ALN and dorsal skin tissue, absolute cell number of CD3e+ T cell, CD4+ Th cell, CD8+ c/sT cell, CD3+CCR3+ cell, CCR3+ cell, CD3+CD69+, CD4+CXCR5+ in ALN, PBMCs, absolute cell number of CCR3+, CD3+/CD69+, CD11b+/Gr-1+, CD11b+/Gr-1+ in dorsal skin tissue, Eotaxin2 mRNA, CCR3 mRNA in dorsal skin tissue and gene expression of IL-5 mRNA, IL-13 mRNA in ALN were significantly decreased. Furthermore, thickness of epidermis infiltrated inflammatory immune cell & mast cell in dermis, histological infiltration of mast cell, the size of inflammatory lymphocytes cells & plasma cells in ALN and histological infiltration of CD4+ & CCR3+in ALN and dorsal skin tissue were significantly decreased as well. Conclusions Concurrent administration of JUJSTK and AJ on atopic dermatitis in an in-vivoexperiment by using an NC/Nga atopic dermatitis mouse was very effective as an atopic dermatitis treatment.
한의학
null
kci_detailed_000248.xml
ART001408913
oai_dc
요로감염이 동반되 소아 요로결석 환아 증례 보고
A Case Report of a Child who has Urolithiasis with Urinary Tract Infections
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "정지호(원광대학교); 안재선(원광대학교); 이해자(원광대학교); 박은정(원광대학교); 김미기(원광대학교); 오지은(원광대학교); 은선헤(원광대학교); 박가영(삼세한방병원)" ]
Objectives A purpose of this study is to report a case study of a child with urolithiasis and urinary tract infections Methods A four-year-old female had been taken Korean traditional medicine for two weeks, and clinical symptoms had been observed. Results Treating with Korean traditional medicine, symptoms of urolithiasis with urinary tract infections has been improved. Conclusions This study supports that Korean traditional medicine can be an effective means of treating internal medicine for urolithiasis with urinary tract infections, and further case studies are needed for more accurate results.
한의학
null
kci_detailed_000248.xml
ART001412247
oai_dc
자폐증 환아의 頭鍼치료 치험 1례
A Clinical Report of Scalp Acupuncture Effects on Autistic Children
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "홍상준(동서한방병원); 최가혜(동서한방병원); 송인선(동서한방병원)" ]
Objectives The study was designed to report the clinical effects of scalp acupuncture on autistic children. Methods These patients were treatedby scalp acupuncture. We observed the improvement of his disease through K-CARS and E-CLAC tests. Results By using scalp acupuncture, we could make a considerable improvement of autistic score(K-CARS). Conclusions Theabove results suggest that scalp acupuncture can be an effective treatment for autistic children.
한의학
null
kci_detailed_000248.xml
ART001412253
oai_dc
韓方治療로 호전된 小兒 腦出血 後遺症 治驗 1例
A Case Report of a Sequela of Intracranial Hemorrhage in Childhood
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "최가혜(동서한방병원); 송인선(동서한방병원); 홍상준(동서한방병원)" ]
Objectives The purpose of the case study is to report the effects of stroke in childhood especially for Intracranial Hemorrhage sequela treated by oriental medical treatment. Methods The patient was treated by herbal medicine, acupuncture, moxa, and physical treatments. Results By using of oriental medical treatment, we could see significant improvement for Stroke symptoms. Conclusions This case study shows that oriental medical treatment can be an effective treatment for Stroke in Childhood. However, the further study with longer, and large clinical trials are needed for accuracy.
한의학
null
kci_detailed_000248.xml
ART001412234
oai_dc
초등학교 4학년 아동의 알레르기 질환 유무에 따른 식습관 및 생활습관 비교
Comparison of Eating Habits and Living Habits in Fourth Grade Elementary School Children with or without Allergic Diseases
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "서희연(대전대학교); 김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives Because allergic disease is currently prevalent and has tendency to become chronic, the purpose of this study is to examine the effects of allergic diseases on eating and living habits of children when they grow. Methods Questionnaire performed by 203 fourth grade elementary school children in Cheonan was analyzed. Results Disease group had low frequency of eating ramen, watching TV or web-surfing than that of normal group, but had higher frequency of eating meat, eating breakfast.
한의학
null
kci_detailed_000248.xml
ART001412241
oai_dc
외상성 뇌손상으로 인한 발달초기장애 환아의 한방적 처치에 관한 증례보고
A Case Report of Primary Developmental Disorder Induced by Traumatic Brain Injury
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "성현경(동국대학교); 민상연(동국대학교); 김장현(동국대학교)" ]
Objectives The purpose of this study is to report the clinical effectsof oriental medical treatment on developmental disorder induced by traumatic brain injuries. Methods The patients were treated with herb medicine, acupunctures, moxibustions, and negative pressures, and then evaluated by manual muscle tests, gross motor function measurements, sequenced language scales for infants. Results The patient's manual muscle power, motility, cognition, speech were significantly improved after six weeks of oriental medical treatment. Conclusions This study showed that oriental medical treatments were effective on developmental disorder induced by traumatic brain injuries. However, further clinical studies were needed.
한의학
null
kci_detailed_000248.xml
ART001412237
oai_dc
허약아 증상연구를 통하여 본 학교생활 부적응의 한의학적 접근
Oriental Medical Research about School Life Maladjustment by Study of the Weak Children Symptoms
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "손미주(대전대학교); 김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives This study is designed to evaluate the relationship between school life maladjustment and oriental medicine by diagnostic procedure based on the symptoms of weak children. Methods The questionnaire administrated to 130 fifth grade elementary school students in Daejeon was analyzed. Results 1. Comparing and analyzing different sexes in terms of school adjustment grades, girls were more adaptable than boys. 2. Weak score didn't show significant difference in sex and in the school adjustment 3. Based on the relationship between a group normal children and a group of children with weak lung, normal children group was more adaptable than group of children with weak lung. Conclusions School life maladjustment should be investigated as a new field of oriental medical treatment and further study needs to be done.
한의학
null
kci_detailed_000248.xml
ART001412261
oai_dc
人蔘固本丸加味方이 흰쥐의 成長에 미치는 影響
The Effect of InsamGobonHwan (IGH) on Growth of Rats Park Sun Young, Baek Jung Han
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "박선영(대구한의대학교); 백정한(대구한의대학교)" ]
Objectives To evaluate the effect of InsamGobonHwan (IGH) on growth of rats. Methods We divided male Sprague-Dawley rats into 4 groups(IGHE1, IGHE2, IGHE3 and sham group). IGHE1, IGHE2, IGHE3 groups were administered with IGHE water extracts once a day at the dose of 1,000, 500 and 250㎎/㎏/10㎖ for 1 week, 2 weeks, and 3 weeks. Sham group was administered with normal saline with using the same method. We measured body weight, amount of body weight increasing, length of femur, serum Growth Hormone(GH), serum Insulin-like Growth Factor-Ⅰ(IGF-Ⅰ), serum Thyroid-stimulating Hormone(TSH) and serum testosterone at 1 week, 2 weeks, and 3 weeks of experiment. Results The body weight and the changes of body weight increased significantly in IGHE1 group compared to sham group after 2 and 3 weeks, and in IGHE2 group after 2 weeks. The lengths of the femur increased significantly in IGHE1 group as compared with sham group after 1, 2 and 3 weeks, and in IGHE3 group after 1 week. The level of IGF-Ⅰ in the serum increased significantly in S1 group as compared tosham group after 1 and 3 weeks, and in IGHE13 group after 3 weeks. The level of TSH in the serum increased significantly in IGHE1group as compared to sham group after 2 and 3 weeks. The level of GH and testosterone in the serum does not change significantly. Conclusions SGT have an effect of promoting growth of rats and might be effect to treat various kinds of growth delay in children.
한의학
null
kci_detailed_000248.xml
ART001412257
oai_dc
蒲公英의 염증성 사이토카인 발현 및 조절에 관한 연구
Inhibitory Effect of Taraxaci Herba Extract (THE) on Pro-inflammatory Mediatory
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "노경호(대구한의대학교); 백정한(대구한의대학교)" ]
Objectives The purpose of this study is to find out the effect of Taraxaci Herba Extract (THE), LPS, on pro-inflammatory mediatory Methods After the treatment of Taraxaci Herba MeOH extract dissolved in EMEM for 1 hour prior to the addition of LPS (1 μg/ml), cell viability was measured by MTT assay, Nitric Oxide production was monitored by measuring the nitrite content in culture medium. And levels of cytokine and PGE2 were analyzed by sandwich immunoassays. Results THE inhibited the production of nitrite and nitrate (0.03 and 0.1 mg/ml), TNF-α, (0.03 and 0.1 mg/ml), IL-1β(0.03 and 0.1 mg/ml), IL-6 (0.01, 0.03 and 0.1 mg/ml) and PGE2(0.03 and 0.1 mg/ml) activated with LPS. In Raw 264.7 cells activated with lipopolysaccharide. Conclusions According to the results above, Taraxaci Herba can produce anti-inflammatory effect, which may play a role in adjunctive therapy in Gram-negative bacterial infections.
한의학
null
kci_detailed_000248.xml
ART001412274
oai_dc
주자독서환의 뇌기능 활성 및 신경세포 보호효과
The Effects of Jujadokseo-hwan on the Activation of Brain and Neuroprotactive Effects
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이유경(동신대학교); 채중원(동신대학교)" ]
Objectives This study is designed to investigate the effects of Jujadokseo-hwan on the brain ability and inducing oxidative stresses. Methods We measured the changes of regional cerebral blood flow and mean arterial blood pressure. Then we analyzed histological examination, immunohistochemistric response and anti-oxidant activity of Jujadokseo-hwan. Results 1. Treatment of Jujadokseo-hwan significantly increased regional cerebral blood flow but decreased mean arterial blood pressure. 2. Treatment of Jujadokseo-hwan-induced increase of regional cerebral blood flow was significantly inhibited by pretreatment with indomethacin (1 ㎎/㎏, i.p.), an inhibitor of cyclooxygenase. 3. In histological examination through TTC stain, group Ⅰ was no change, but group Ⅱ showed that discolored in the most cortical part. Group Ⅲ showed that decreased discolor in the cortical part. 4. In immunohistochemistric response of BDNF, group Ⅱ showed that lower response effect . Group Ⅲ showed that increase response effect . 5. Treatment of Jujadokseo-hwan increased proliferation rates of Glial cell effectively 6. Treatment of Jujadokseo-hwan accelerated proliferation rates of C6 cells in vitro. In addition, protective effects on cell death induced by paraquat, rotenone and hydrogen peroxide. In addition, activity of SOD were increased by treatment with Jujadokseo-hwan. Conclusions In conclusion, Jujadokseo-hwan can improve of the brain ability , learning ability , memory ability and induce ischemic brain injuries.
한의학
null
kci_detailed_000248.xml
ART001412270
oai_dc
갈근추출액이 알레르기 염증반응에 미치는 영향
The Effects of Puerariae Radix on Allergic Inflammation
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김홍배(동의대학교); 강경화(동의대학교); 황원덕(동의대학교); 유선애(동의대학교); 이승연(동의대학교)" ]
Objectives To study the effects of Puerariae Radix (PR) on allergic inflammation. Methods In vivo, Animals were orally administrated with PR once a day for 5 days. Then, we investigated compound 48/80-induced active systemic anaphylatic shock using ICR mice and anti-DNP IgE-induced passive cutaneous anaphylaxis using Sprague Dawley rat. In vitro, we measured cell viability, b-hexosaminidase release, IL-4, TNF-a and PGE2 secretion and IL-3, IL-4, TNF-a, COX-2 and iNOS mRNA expression from RBL-2H3 cells after treatment of PR. Results In vivo, PR pretreatments inhibited compound 48/80-induced active systemic anaphylatic shock. Passive cutaneous anaphylaxis was inhibited. In vitro, 0 ~ 1% PR treatments were not affect on cell viability and inhibited b-hexosaminidase release, IL-4, TNF-a and PGE2 secretion. PR treatments also decreased IL-3, IL-4, TNF-a, COX-2 and iNOS mRNA expression in RBL-2H3 cells. Conclusions These results suggest that PR may be beneficial in the inhibition of allergic inflammatory response.
한의학
null
kci_detailed_000248.xml
ART001412280
oai_dc
凉血除濕湯이 DNCB로 유도된 NC/Nga mice의 아토피 피부염에 미치는 영향
Effect of Yanghyeoljeseuptang (YHJST) Composition on Atopic Dermatitis NC/Nga Mice Induced by DNCB(dinitrochlorobenzene)
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "박두병(대전대학교); 김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives The purpose of this study is to investigate the effect of YHJST on atopic dermatitis in an experiment using an NC/Nga mice induced by DNCB, which has histological and clinical similarities to the condition in humans. Methods To investigate the effect of YHJST on atopic dermatitis(AD), we evaluated atopic dermatitis-like skin lesions by clinical skin index and analyzed immunological parameters in peripheral blood mononuclear cells(PBMCs) and performed skin histology in ears and dorsal skin of NC/Nga ato-mouse. Results YHJST medicines decreased Serum level of IgE, IL-6, TNF-α. Also total number of CD69+, CD3+ in PBMCs, absolute cell number of CCR3+CD3+, CD11b+Gr-1+ in Dorsal skin tissue, Serum IgG1, IgM, IgG2a and IgG2b decreased significantly. Furthermore YHJST is extremely effective to histological symptoms; dermal and epidermal thickening, hyperkeratosis and inflammatory cell infiltration and suppressed histologic infiltration of CD4+& CCR3+ in ear and dorsal skin lesions significantly. YHJST decreased gene-expression of IL-6, TNF-α, CCR3, Eotaxin mRNA than that of control group. Conclusions YHJST on atopic dermatitis to atopic dermatitis NC/Nga mouse induced DNCB was incredibly effective.
한의학
null
kci_detailed_000248.xml
ART001412245
oai_dc
기능성 소화불량증으로 腹部脹滿이 지속되는 환아 증례 1례 보고
A Case Report of Functional Dyspepsia with Abdominal Distention
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김초영(경희대학교); 장규태(경희대학교)" ]
Objectives This study is to report a case that has an important meaning as a result of treating functional dyspepsia with oriental treatment. We investigated functional dyspepsia in 6 years child who had to continue abdominal distention for a month after gastroenteritis. The child has recovered from all dyspepsia symptoms after treating with oriental medicine. Methods The patient had dyspepsia symptoms all day, especially repeated abdominal distention. He sometimes had nausea, vomiting, diarrhea, abdominal pain. For those symptoms, we treated him with herbal medicine and acupuncture. The aim of treatment was to improve functional dyspepsia without western treatment. We measured patient's abdomen circumference for change of abdominal distention. Results The symptoms of functional dyspepsia were vanished and the patient maintains his condition with oriental medicine treatment without western treatment. After herb medicine treatment and acupuncture treatment the patient's dyspepsia symptoms (nausea, vomiting, diarrhea, abdominal pain, and abdominal distention) were vanished and maintained his condition for two months after complete the treatment. Conclusions This study showed that oriental medicine can elevate the functional dyspepsia children's quality of life with continuous health care and treatment. For more accurate studies, further studies would be needed with more cases.
한의학
null
kci_detailed_000248.xml
ART001412265
oai_dc
저출력 레이저 치료(LLLT)가 아토피 피부염의 증상 완화에 미치는 영향
The Effects of Low Level Laser Therapy on Decrease of Atopic Dermatitis Symptoms
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "윤혜준(경희대학교); 윤종성(신창한의원); 김덕곤(경희대학교); 이진용(경희대학교)" ]
Objectives The purpose of this study is to evaluate the effects of Low Level Laser Therapy on Atopic dermatitis symptoms. Methods 19 patients (7 men, 12 women) were involved in this study. The intensity of SCORAD index (Erythema/darkening, Edema/papulation, Oozing/crust, Excoriation, Lichenification/prurigo, Dryness) and the symptom of SCORAD index (Pruritus) in two regionswere measured. One region was treated by LLLT, the other region was not treated. Then a comparative study of index score of two regions was analyzed. Results After treatment, there were statistically significant differences in Edema/papulation, Excoriation (p<0.001), Oozing/crust (p<0.01), and Pruritus(p<0.05) index. Conclusions Based on the results, we concludedthat LLLT is an effective in the treatment of atopic dermatitis. Also, further controlled studies with clinical cases of appropriate treatment time, wavelength, and intervals are needed.
한의학
null
kci_detailed_000248.xml
ART001412266
oai_dc
防風通聖散으로 치료한 소아 乾癬 3례
Three Cases Report of Children Psoriasis treated by Bangpungtongsungsan
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이기훈(강남동약한의원); 장규태(경희대학교)" ]
Objectives The purpose of these 3 cases study is to report the effects of psoriasis children treated by oriental medicine. Methods The subjects are 3 children diagnosed as having psoriasis. These patients were treated by oriental herbal medicine(Bangpungtongsungsan). We observed the improvement of skin condition by Psoriasis Area and Severity Index(PASI) score. Results After treatment, the symptoms of psoriasis were relieved. PASI score of three children in psoriasis was respectively changed from 7 to 0, 2.4 to 0, 3.6 to 0. Conclusions This study shows that Bangpungtongsungsan can be an effective treatment for psoriasis. Further study in needed with more cases of treatment.
한의학
null
kci_detailed_000248.xml
ART001340773
oai_dc
소아의 사상체질별 신체 특성의 차이에 관한 연구 -Zema21을 통한 체질분석 및 체성분검사와의 상관관계를 중심으로-
The Relationship Between Zema 21 and Inbody Based on the Sasang Constitutional Differences of Children
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "서정민(대구한의대학교); 이유진(대구한의대학교); 윤혜진(대구한의대학교); 강미선(대구한의대학교); 백정한(대구한의대학교)" ]
Objectives The purpose of this research is to find out the relationship between Zema 21 and in body based on the Sasang Constitutional difference of children. Methods We collected 1050 children from 5 years old to 15 years old who had been tested for both Zema21 and Inbody in ○○ oriental hospital from the period of September 1, January 1999 to August 31, 2008. This research investigated the Constitutional differences based on the relationship between Zema21 and Inbody. Results 1. It turned out that the children’s height does not have a significant relationship between their age and gender. 2. Generally, Taeumin’s weights were significantly high than those of Soyangin’s and Soumin’s in certain ages in children over 9 years old and in all genders. 3. The percentage of the body fat in Taeumin were significantly high than Soyangin and Soumin in certain ages in children over 10 years old and in all genders. 4. Waist-Hip ratio in Taeumin were significantly high than Soyangin and Soumin in male over 10 years old and in female over 13 years old of children. On the other hand, there was no relationship to the Soyangin and Soumin. 5. The obesity degree in Taeumin were significantly high in all female and male who were over 10 years old. Soyangin were the next highest group and Soumin follows. 6. Body Mass Index in Taeumin were significantly high in all genders who were over 10 years old. The second is Soyangin, and the lowest groupis Soumin. 7. The Basal Metabolic Rate resulted as significant in all age, although this does not have any relationship between age and gender. 8. Abdomen out in Taeumin were significantly high in ages over 10 and genders. The second is Soyangin and the lowest is Soumin. 9. Hip circumference Abdomen out in Taeumin were significantly high in ages over 10 and genders. Specially, Taeumin shows highest value, then the second is Soyangin, and the lowest is Soumin who were over 12 years old. Conclusions The results of Inbody were not significant to the children who were under 9 years old. Taeumin became significantly fat after over 10 years old. The results of Body Composition except height and Basal Metabolic Rate(MBR) were the highest in Taeumin, and Soyangin and Soumin were the second, and the third respectively.
한의학
null
kci_detailed_000248.xml
ART001340775
oai_dc
消肥飮이 비만아의 체질량지수와 비만도 감소에 미치는 영향
The Effects of Sobieum on Decrease of Body Mass Index (BMI) and Obesity Index of Obese Children
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이동형(경희대학교); 김덕곤(경희대학교)" ]
Objectives The purpose of this study is to evaluate the effects of Sobieum on decrease of BMI and obesity index of obese children. Methods 66 children (33 boys, 33 girls) were involved in this study. We measured height and weight for each time their visit, and calculated BMI and obesity index. Results After medication, BMI level and obesity index were significantly reduced (p<0.001). Conclusions We speculate that Sobieum is effective in the treatment of childhood obesity, and further controlled studies are needed with clinical cases of hematological evaluation.
한의학
null
kci_detailed_000248.xml
ART001340762
oai_dc
주의력결핍 과잉행동 장애의 原因 및 病機에 따른 한방음악치료의 機法에 관한 연구
The Study on Treatment of Attention Deficit Hyperactivity Disorder by Oriental Medicine Music Therapy
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이승현(경희대학교); 김여진(경희대학교)" ]
Objectives The purpose of this study is to introduce oriental medicine music therapy related to the treatment of ADHD. Methods This study observed ADHD from the oriental medical point of view and tried to treat this disease with the oriental medicine music therapy. Results ADHD is caused by excess of Yang energy, flaming-up of fire, blood deficiency of the heart and the spleen, deficiency of the kidney essence, and instability of emotions. The ADHD patients with the case of excess of Yang energy and flaming-up of fire, patients were played Fire-Gi rhythm as a treatment, and they listened to Metal-Gi music. Whereas, the ADHD patient with blood deficiency of the heart and the spleen, invigoration of vital energy music therapy can be used. Another case of ADHD patients with deficiency of the kidney, Water-Gi rhythm and replenishing vital essence music therapy can be used. According to the patients' seven modes of emotions, the proper music should be chosen. Conclusions Oriental medicine music therapy can be a new type of treatment for ADHD patients.
한의학
null
kci_detailed_000248.xml
ART001340735
oai_dc
아토피樣 피부염 NC/Nga생쥐에서 加減消毒飮의 투여가 피부염에 미치는 영향
Effects of Kakamsodokum (KKSDU) on Atopic Dermatitis-like Skin Lesions in NC/Nga Mouse
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "송현지(대전대학교); 김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives The purpose of this study is to investigate the effect of Kakamsodokum (KKSDU) on atopic dermatitis in an in-vitro experiment using an NC/Nga atopic dermatitis mouse, which has histological and clinical similarities to the condition in humans. Methods We evaluated IL-1β, IL-6, TNF-α, TGF-β, IL-10 mRNA, CD4+/IFN-γ+, and CD4+CD25+foxp3+ in B and T cells of NC/Nga atopic dermatitis mouse by real-time PCR and intracellular staining in vitro. Results KKSDU medicines supressed IL-1β, IL-6, TNF-α, TGF-β mRNA and increased IL-10 mRNA in B cells. CD4+/IFN-γ and CD4+CD25+foxp3+ in T cells were increased by KKSDU. Conclusions KKSDU on atopic dermatitis might be very effective to the atopic dermatitis treatment.
한의학
null
kci_detailed_000248.xml
ART001340754
oai_dc
麝香 및 麝香 配合 韓藥製劑의 口腔 投與가 白鼠의 記憶 및 腦機能 活性에 미치는 영향
The Effects of Moschus and Herbal Combination with Moschus by Oral Administration at Memory and Activation of Brain Ability on Rats
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "정현주(동신대학교); 채중원(동신대학교); 이유경(동신대학교)" ]
Objectives This study was investigated to find how the orally administrated Moschus, herbal combination with Moschus, and herbal combination improves the rats’ memory and rats’ liver. These medications are generally known asthe memory improvement. Methods This study used the Sprague Dawley rats. They were divided into two groups – SD rats and orally administrated Saline(Control group). 0.473 mg/kg Moschus(HM-A), 153.9 ㎎/㎏ herbal composition without Moschus(HM-B), and 165.95 ㎎/㎏ herbal composition with Moschus combined(HM-C) Control, saline were orally administered. Each group was trained in the eight-arm radial maze task at the conditions of before oral administrated, and also right after third, sixth, and eighth by oral administration. Lastly, these animals were killed and were tested for brain tissue and serum AST/ALT level to measure how the medications were effected to the liver function. Results The result of radial eight-arm maze task test, the HM-B and HM-C groups showed significant decrease in mistakes from the fourth day of testing. Whereas, the HM-A group showed increasing in the error rate. HM-A and HM-C group of rats had significantly increased amount of acetylcholinesterase in the CA1 region of hippocampus, compared to the control group. Whereas, HM-B and HM-C group had increased level of ChAT compared to the control group. On the other hand, each experimental group did not show any significant difference to the level of serum AST/ALT and the weight ratio of the liver to the body. Conclusions This study provided evidences that the orally administered memory improvement herbal medication, and Moschus were effective to improve memory.
한의학
null
kci_detailed_000248.xml
ART001340741
oai_dc
고열, 발진을 동반하는 전신형(systemic) 소아기 류마티스 관절염(juvenile rheumatoid arthritis; JRA) 환아 증례 1례 보고
A Case Report of Systemic Type Juvenile Rheumatoid Arthritis with Fever and Eruption
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "유창길(유창길한의원); 이윤주(유창길한의원)" ]
Objectives This study is to report a case that has an important meaning as a result of treating Juvenile Rheumatoid Arthritis. We investigated a patient who had to maintain his life with western medicines such as DMARDs, NSAIDs and steroids for a long time. The patient has recovered from all symptoms and his ESR, CRP has been back to normal range with oriental medicine treatment. Methods The patient had fever, especially repeated fever during the afternoon, pain and swelling of joints, generalized skin eruption, anorexia, delayed growth, weight loss, fatigue. So we treated him with herbal medicine and reduced his western medicine. The aim of treatment was recovery from Juvenile Rheumatoid Arthritis after discontinuance of all western medicine. Results The symptoms of systemic type Juvenile Rheumatoid Arthritis was vanished and the patient maintains his condition with oriental medicine treatment after stopped all DMARDs such as MTX(methotrexate) and NSAIDs. His ESR and CRP levels were back to the normal range. After this treatment the patient's height and weight has been increased which showed a significant meaning in growth to the child. Conclusions This study showed that oriental medicine can elevate the Juvenile Rheumatoid Arthritis patient's quality of life with continuous health care and treatment for major problem. For more accurate studies, further studies would be needed with more cases.
한의학
null
kci_detailed_000248.xml
ART001340746
oai_dc
수면중 간질발작을 주소로 하는 증후성 간질 환아 증례 보고
A Case Report of Symptomatic Epilepsy
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김윤영(동국대학교); 민상연(동국대학교); 김장현(동국대학교)" ]
Objectives The purpose of this study is to report a case which gave various remarkable epilepsy treatment results by using oriental medicine. Methods We treated the patient with acupuncture as a main treatment and herbal medicine. We also recommended to the patient and patient’s parents to continue oriental medical treatment for 2 years from now because symptomatic epilepsy is a type of disease which needs long term care. Results The epileptic seizure has been well controlled for 12 months so far, and the results was recorded by EEG. The EEG level was in normal range. Conclusions Even though this is only one case of the study but this case has an important meaning because the epilepsy was treated by oriental medicine, especially acupuncture treatment. The control of the symptomatic epileptic seizure was effective by means of increasing patient's quality of life. Further studies about effective treatment of symptomatic epilepsy would be needed with more various cases.
한의학
null
kci_detailed_000248.xml
ART001341008
oai_dc
뇌성마비의 鍼刺 치료에 대한 문헌적 고찰 -최근 중의잡지를 중심으로-
A Literature Study on Acupuncture for Cerebral Palsy -Based on the Current Traditional Chinese Medical Journals-
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "하수연(동국대학교); 민상연(동국대학교); 김장현(동국대학교)" ]
Objectives The purpose of this study is to investigate the current acupuncture therapy of cerebral palsy. Methods We investigated the Chinese clinical papers which were published in the last 10 years(from 1999 to 2008). We found these papers from the oriental medical library in university and we also used the China National Knowledge Infrastructure(CNKl) through the internet and selected 32 papers for analyzing. Results Most papers were described the effect of acupuncrure or acupoint-injection. This is more effective way to treat than the general rehabilitation treatment such as the physical therapy, the occupational therapy, and the speech therapy. Acupuncture or acupoint-injection has overall 80~100% of rehabilitation rate. The younger the children were, the longer the treatment period was, and the more successful in treatment. The acupuncture was often used with the general acupuncture and scalp acupuncture. Commonly used major acupuncture points were sishencong(四神聰), bohui(百會), zusanli(足三里), yundongqu(運動區), pinghengqu(平衡區), quchi(曲池), and sanyinjiao(三陰交). Commonly used main meridian pathways were bladder, governor vessel, gallbladder, large intestine, stomach, small intestine meridian. Head is the common site for acupuncture. The main acupoint-injection points were zusanli(足三里), dazhui(大椎), shenshu(腎兪), yamen(啞門), neiguan(內關), and fengchi(風池). For the injection, brain activator, ganglioside Ml, cerebroprotein hydrolysate, cytidine diphosphate choline, Vit Bl, Vit B12, the salviae root, the safflower were commonly used. Conclusions Acupuncture and acupoint-injection have been shown as an effective treatment on cerebral palsy. The acupuncture was used often the general acupuncture and scalp acupuncture all together. Commonly used main acupuncture points were sishencong, bohui, zusanli, yundongqu, pinghengqu, quchi, sanyinjiao.
한의학
null
kci_detailed_000248.xml
ART001340771
oai_dc
薏苡仁의 염증성 사이토카인 발현 및 조절에 관한 연구
Inhibitory Effect of Coicis Semen Extract(CSE) on Pro-inflammatory Mediatory
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "윤혜진(대구한의대학교); 이유진(대구한의대학교); 강미선(대구한의대학교); 백정한(대구한의대학교)" ]
Objectives This study was evaluated the effects of CSE the regulatory mechanism of NO and cytokines in the LPS-stimulated Raw 264.7 cells. Methods The Coicis Semen MeOH extract dissolved in EMEM for 1 hour prior to the addition of LPS(1μg/ml). The cell viability was measured by MTT assay, and Nitric Oxide production was monitored by measuring the nitrite content in culture medium. The levels of cytokine and PGE2 were analyzed by sandwich immunoassays. Results CSE inhibited the production of NO (0.03 and 0.1 mg/ml), TNF-α (0.03 and 0.1 mg/ml), IL-1β (0.03 and 0.1 mg/ml), IL-6 (0.03, 0.1 mg/ml) and PGE2(0.03 and 0.1 mg/ml) in Raw 264.7 cells activated with LPS(lipopolysaccharide). Conclusion According to the results above, Coicis Semen can produce anti-inflammatory effect, which may play a role in adjunctive therapy in Gram-negative bacterial infections.
한의학
null
kci_detailed_000248.xml
ART001340731
oai_dc
理中湯이 IgE가 과잉생성되고 피부염이 유발된 NC/Nga생쥐에서 IFN-γ 반응에 의한 Th2 세포분화 억제에 미치는 영향
The Effect of Li Zhong Tang on the Suppression of Th2 Differentiation by IFN-γ Response in IgE Hyperproduction and Atopic Dermatitis-like Skin Lesions Induced NC/Nga Mouse
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "서희연(대전대학교); 김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives The purpose of this study is to investigate the effect of Li Zhong Tang(LZH-T) on atopic dermatitis by using NC/Nga atopic dermatitis mouse. Methods First, in vitro, we isolated B cells from NC/Nga mouse which induced atopic dermatitis-like skin for 18 weeks. We analyzed FACS by intracellular staining of IFN-γ, GATA-3+ and also analyzed cytokines by using real-time PCR. Secondly, in vivo , after administration of LZH-T to the 12 weeks old mouse with atopic dermatitis. We analyzed serum IgE, IFN-γ level and observed the changes of activated cell. Results In vitro, LZH-T decreased the levels of CD4+/IFN-γ+ and increased the levels of CD4+/GATA3+. In vivo, serum IgE levels were decreased and IFN-γ levels were increased in LZH-T group compared to the control group. In PBMCs, the percentage of activated cell - granulocytes, CD3+, CD3+CD4+, B220+CD23+, and CCR3+ were decreased and CD19+, CD3+CD8+ were increased in LZH-T group compared to the control group. Conclusions This study demonstrates immunological activity of GPJST on atopic dermatitis-like model mice.
한의학
null
kci_detailed_000248.xml
ART001340737
oai_dc
아토피 피부염 동물 모델에서 아토피 크림과 紫雲膏의 병용도포가 피부염에 미치는 영향
Effects of Atopy Cream-combined with Jawoongo Ointment on the Development of Atopic Dermatitis-like Skin Lesions in NC/Nga Mouse
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "여의주(대전대학교); 김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives The purpose of this study is to investigate the suppressive effects of Atopy cream-combined with Jawoongo ointment (A-J), on the development of atopic dermatitis-like skinlesions in NC/Nga mouse. Methods We evaluated clinical skin score, hematology and Serum total IgE and IgG1 of NC/Nga atopic dermatitis mouse, analyzed the cytokine level, total cell number, Immunohistochemical staining and Histological features of axillary lymph node(ALN), draining lymph node(DLN), peripheral blood mononuclear cells(PBMCs) and dorsal skin tissue in NC/Nga mouse. Results A-J decreased the clinical skin score, total cell number of WBC, platelet, neutrophils, eosinophils in blood, Serum total IgE & IgG1, IL-5, IL-13. Also, total cell number of ALN and dorsal skin tissue, Absolute cell number of CD3e+&CD19+, CD4+&CD8+, CD3+/CCR3+, CCR3+, CD3+/CD69+, CD3+/CXCR5+ in ALN, PBMCs, Absolute cell number of CCR3+, CD3+/CD69+, CD11b+/Gr-1+ in dorsalskin tissue, Eotaxin2 mRNA, CCR3 mRNA in dorsal skin tissue and gene expression of IL-5 mRNA, IL-13 mRNA in ALN decreased significantly. Furthermore, thickness of epidermis, infiltrated inflammatory immune cell and mast cell in dermis, histologic infiltration of mast cell, the size of inflammatory lymphocytes cells and plasma cells in ALN and histologic infiltration of CD4+ & CCR3+ in ALN and dorsal skin tissue decreased significantly. However, total cell number of DLN, absolute cell number of CD3e+&CD19+, CD4+&CD8+, B220+/CD23+, CD3+/CD69+ increased significantly. Conclusions A-J was the successful treatment of atopic dermatitis in a NC/Nga mouse model.
한의학
null
kci_detailed_000248.xml
ART001340766
oai_dc
瓊玉膏加味方이 흰쥐의 成長에 미치는 影響
The Effect of KyungOcGogamibang on the Growth of the Rats
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "정봉균(대구한의대학교); 윤혜진(대구한의대학교); 이유진(대구한의대학교); 강미선(대구한의대학교); 백정한(대구한의대학교)" ]
Objectives The purpose of this study is to find out the effect of KyungOcGogamibang(KOGE) on the growth of rats. Methods First of all, we divided male Sprague-Dawley rats into 4 groups(KOGE1, KOGE2, KOGE3 and control group). Then KOGE1, KOGE2 and KOGE3 groups were administered with KOGE water extracts once a day at a dosage of 250, 500, 1,000㎎/㎏ respectively for 3 weeks. The control group was administered with normal saline in the same manner. We measured the rat's body weight, amount of body weight increased, length of femur, serum GH, serum IGF-Ⅰ, serum TSH and serum testosterone after each week of administration. Results 1. There were significant changes of the rat's body weight, the length of the femur, the level of GH, IGF-Ⅰand TSH in KOGE1 groups. 2. There were significant changes of the rat's body weight, the length of the femur, the level of IGF-Ⅰand TSH in KOGE2 groups. 3. There were significant changes of the rat's body weight, the length of the femur, the level of IGF-Ⅰand TSH in KOGE3 groups. Conclusions According to the results above, rat in KOGE group have been increased their body weight, length of femur, serum GH, serum IGF-1 compared to the control group. This study shows that groups of KOGE have an effect on promoting the growth, thus it is expected to treat growth problems for children.
한의학
null
kci_detailed_000248.xml
ART001340764
oai_dc
한국어판 아동식습관 설문지(Korean Children's Eating Behaviour Questionnaire, K-CEBQ)의 타당화 예비연구
Pre-study of Validation of the Children's Eating Behaviour Questionnaire in Korean Children
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이민정(경희대학교); 장규태(경희대학교); 한윤정(경희대학교)" ]
Objectives In this study, we obtained Korean version of CEBQ (Children's Eating Behaviour Questionnaire) and verify whether it is reliable or not. Methods Total 106 parents completed this questionnaire, and we gathered children's BMI data and examined the relationship between children's BMI and mean scale scores. Results 1. This study results confirmed the theorectical factor structure, with acceptable internal reliability and between-subscale correlations. 2. There are significant mean scale scores difference between anorexia group and control group. 3. There are significant relations between children's BMI and mean scale scores. Conclusions The results support the use of the CEBQ as a phsychometrically sound tool for assessing children's eating behaviours in Korean children.
한의학
null
kci_detailed_000248.xml
ART001303946
oai_dc
驅風除濕湯이 DNCB로 유도된 NC/Nga mice의 아토피 피부염에 미치는 영향
Effect of Gupoongjeseuptang (GPJST) on DNCB (dinitrochlorobenzene)-induced Atopic Dermatitis-like Model NC/Nga Mice
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "윤재은(대전대학교); 김윤희(대전대학교); 한재경(대전대); 김윤희(대전대학교)" ]
Objectives The purpose of this study is to investigate the effect of Gupoongjeseuptang (GPJST) on atopic dermatitis by in vivo experiment using NC/Nga atopic dermatitis mouse, which has histological and clinical similarities to the atopic dermatitis of human. Methods To investigate the effect of GPJST on atopic dermatifis, we evaluated atopic dermatitis-like skin lesions by clinical skin index and analyzed immunological parameters in peripheral blood mononuclear cells (PBMCs), splenocytes, draining lymph node (DLN) and performed skin histology in ears and dorsal skin of atopic dermatitis-like skin NC/Nga mouse in vivo. Results In vivo, clinical skin severity score were significantly lower in GPJST group than control group. IgE, IL-6, TNF-α, IgG1, IgM, IgG2a and IgG2b levels in serum decreased remarkably in GPJST group than control group. Also, total absolute number of CD3+CD69+, and CCR3+ cells recovered as normal in PBMCs and CD3+, CD3+CD69+ decreased significantly compared with control group in isolated DLN from NC/Nga mouse and total absolute number of CD11b+Gr-1+, CCR3+CD3+ in dorsal skin of NC/Nga mouse decreased by GPJST. We analyzed ear and neck-back skin after biopsy and dyeing by hematoxyline/eosin (H&E) and toluidine staining (mast cells marker) and obtained results that GPJST are very effective to histological symptoms (dermal and epidermal thickening, hyperkeratosis and inflammatory cell (CD4, CCR3+) infiltration). Conclusions This study demonstrates immunological activity of GPJST on atopic dermatitis-like model mice.
한의학
null
kci_detailed_000248.xml
ART001303887
oai_dc
한약인성 간손상의 원인산정법으로 도입된 진단 척도(Modified RUCAM scale)에 대한 임상적 고찰
A Clinical Study on the Modified RUCAM Application to Liver Injury Induced by Herbal Medicine
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "천진홍(동국대학교); 민상연(동국대학교); 김장현(동국대학교)" ]
Objectives The purpose of this study is to confirm severe problem caused by using a modified RUCAM scale than that officially recognized to diagnose liver injury induced by herbal medicine. Materials and Methods Cases with liver injury induced by herbal medicine received to a related institute from January 2004 to December 2007 were collected and evaluated by the original scale and modified scale. Results 1. Based on this study, we couldn't clinicaly confirm that the case was not excluded by the relieved first item basis of modified RUCAM scale which has to be excluded by the first item basis of orginal RUCAM scale. 2. By modified 6th item, one score was added to the total score. 3. By adding 8th item, it gaind one point to the whole the total score. Conclusions In this study, we can clinically confirm that the modified RUCAM application to case with liver injury induced by herbal medicine is a severe problem.
한의학
null
kci_detailed_000248.xml
ART001303833
oai_dc
뇌성마비의 조기치료에 관한 문헌적 고찰-최근 중의 잡지 중심으로-
A Literary Review on Early Treatment of Cerebral Palsy -Centered on the Chinese Medical Journal-
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "곡수영(동의대학교); 이승연(동의대학교); 유선애(동의대학교)" ]
Objectives This study has been carried out to look into the methods of early treatment of cerebral palsy and the treatment effect by ages. Methods The fifteen theses dealing with treatment effects by ages were analyzed, which were selected from the 121 theses retrieved out of the wu-ruan(五軟), wu-chi(五遲), wu-ying(五硬), naotan(腦癱), naoxing-tanhuan(腦性癱瘓), during the period between the January 2004 to August 2008 by using the China Academic Journal(CAJ) of China National Knowledge Infrastructure(CNKI). Results 1. Among the study objects in the 15 theses, it was identified that there were 1.97 times more boys with cerebral palsy than that of girls, and it appeared that there was no significant relationship between gender and the treatment. 2. The early treatment referred to the treatment which was carried out based on the early diagnosis within 6 months to one year after the birth. This is the time when the adaptability and plasticity of the brain are high, and it was found out that the treatment effective as babies are young. 3. For the treatment of cerebral palsy, the combination of Traditional Chinese and Western Medicine Therapy was more frequently used than the exclusive Chinese medical treatment method, and it was more effective. Especially in the case, the Chinese medical treatment was focused on the acupuncture and the Tuina Massage. Conclusions 1. For the treatment of cerebral palsy, when the age between one and two years old was established as the standard. The younger the babies were, the higher treatment effects were obtained. 2. It appeared that the early treatment of oriental medicine had relatively excellent effects on cerebral palsy, but it turned out that we needed more studies for accurate results.
한의학
null
kci_detailed_000248.xml
ART001303849
oai_dc
국내 시판중인 소아용 피부 보습 제품의 분석 및 고찰
Analysis of Baby Moisturizers Marketing in Korea
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김윤영(동국대학교); 서영민(동국대학교); 김장현(동국대학교)" ]
Objectives The purpose of this study is to analyze the baby moisturizers and give information about basis of herbal moisturizer. Methods We selected 243 goods by searching with keywords as "baby moisturizer" at 6 major web search engines, 12 web shopping malls in Korea. 10 items were evaluated under three evaluation criteria such as type of product, ingredient and function of goods. Results Study resulted that the most type of moisturizers were lotion type. 80% of the products contained medical agents. Ingredients of medical agents were herbal medicine, aroma oil, vitamin and extract. The moisturizer for atopic dermatitis contained ceramide about half. The ingredient of herbal medicine existed usually as excipients, not as active ingredient. Conclusion It is necessary to study and develop new products contained herbal medicine as active ingredient based on the oriental medical theory.
한의학
null
kci_detailed_000248.xml
ART001303919
oai_dc
韓方治療로 호전된 肥滿으로 인한 小兒의 脂肪肝 治驗 2例
Two Cases Reports of Chlid Fatty Liver with Obesity
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "최가혜(동서한방병원); 김하얀(동서한방병원); 송인선(동서한방병원)" ]
Objectives The purpose of these 2 case studies are to report the effects of fatty liver children treated by oriental medical treatment. Methods These patient was treated by herbal medicine, acupuncture, moxa, consultation. We observed the improvement of his disease by checking GOT, GPT, GGT, TG, and BMI. Results By use of oriental medical treatment, we could make a considerable improvement of Child fatty liver. Conclusions These 2 case studies shows that oriental medical treatment can be an effective treatment for Child fatty liver. And the further study is needed with more cases and longer duration.
한의학
null
kci_detailed_000248.xml
ART001303767
oai_dc
轉換障碍 患兒 1例에 대한 證例報告
A Clinical Report of Conversion Disorder
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김하얀(동서한방병원); 최가혜(동서한방병원); 송인선(동서한방병원)" ]
Objectives The purpose of this study is to report a case of conversion disorder child treated by oriental medical treatment. Methods We diagnosed the patient as Soeumin Woolgwang disease and treated him with herbal medicine, acupuncture, moxa, consultation. We observed the improvement of his disease by checking his pseudo-seizure, stool, headache and chest discomfort. Results By use of oriental medical treatment, we could make a considerable improvement of pseudo-seizure and other symptoms(stool, headache and chest discomfort). Conclusions This study shows that oriental medical treatment can be an effective treatment for conversion disorder. But the symtoms may recur, so we need continuous observation and management.
한의학
null
kci_detailed_000248.xml
ART001303786
oai_dc
한약 투여가 사춘기 전 소아의 신장성장에 미치는 영향에 대한 예비 연구
Pilot Study of Effect to the Growth after the Administration of Herbal Medicine to the Prepuberty Children
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "정민정(동의대학교); 곡수영(동의대학교); 이승연(동의대학교)" ]
Objectives The aim of this study was to evaluate the effect to the height-growth after the administration of herbal medicine to the prepuberty children Methods This clinical study has been carried out with 18 children, who visited to the Department of Pediatrics, Dong-eui oriental medical center from January 2005 to August 2008. They had been treated for height-growth with herbal medicine more than 6 months. This study has been carried out by chart-review to see the effectiveness. Height percentile, BMI and GV(Growth Velocity) after medication was compared with the ones before medication. Results 1. This clinical study has been carried out with 18 children, 12 boys(66.7%) and six girls(23.3%). Their average age was 10.30 years old. 2. Generally total children's average height percentile was increased compared to after medication. Especially eight of them has significantly increasd height percentile(44.4%). 3. Total children's average GV/6months was also increased after medication. Especially ten of them has significantly increasd GV/6months (55.6%). 4. Total children's average BMI also increased (17.01 to 17.85) after medication. Conclusions Herbal medicine affects to the growth of pre-puberty children.
한의학
null
kci_detailed_000248.xml
ART001303751
oai_dc
초등, 중학교 비만 아이들의 韓醫學的 氣, 血, 水 辨證 분석
Analysis of Symptom Pattern through Obesity of Qui Xui Shui in Adolescent School Students
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "조성민(경희대학교); 김덕곤(경희대학교)" ]
Objectives This study was designed to evaluate completely the relationship between obesity and Qui Xue Shui diagnostic procedure in primary and middle school students. Methods The study participants were the 1, 2nd grade students of middle school and 5, 6th grade students of primary school in Kang dong Gu of Seoul (1134 Students). The participants were measured for their height and weight etc, and they were also surveyed by questionnaire. We diagnosed the students as when they scored 10 points or behind on Qui Xue Shui(QXS) question problems from Japan education academy. Results and Conclusions The mean QXS score in the obese group was significantly higher than that of the normal body weight group and the obeser they are, the higher QXS score is. The Qi xu, Qi yu, Xue xu, Shui chi score of the QXS questions the obese group was higher than the normal group. The total QXS score was significantly higher in the obese group. It is shown that the total score of using the Qui Xue Shui diagnostic procedure is mainly dependent on obesity.
한의학
null
kci_detailed_000248.xml
ART001303882
oai_dc
설사를 동반한 장간막 림프절염 환아 증례 보고
A Case Report of Mesenteric Lymphadenitis with Diarrhea
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "정지호(원광대학교); 이해자(원광대학교); 박은정(원광대학교); 오지은(원광대학교)" ]
Objectives The purpose of this study is to report a case of nine-year-old female pediatric patient who had diagnosed as mesenteric lymphadenitis with abdominal pain. Methods The patient was treated by acupunture (acupoint: Hegu(LI4), Zusanli(S36), Zhongwan(CV12), Tianshu(S25)), indirect moxibustion and herb medicine (Koakhyangjeonggisan-kamibang, Jakyakgamchotang Ex) for one week. We observed clinical progress. Result and conclusions After oriental medical treatment, symptoms of mesenteric lymphadenitis (day and night abdominal pain, diarrhea) were improved. This study showed that oriental medicine can be a meaningful treatment for mesenteric lymphadenitis. For more accurate studies, further treatment cases would be needed.
한의학
null
kci_detailed_000248.xml
ART001372983
oai_dc
아토피樣 피부염 NC/Nga생쥐에서 滋陰除濕湯加減의 투여가 피부염에 미치는 영향
ffects of JaUmJeSeupTangKaKam (JUJSTK) on Atopic Dermatitis-like Skin Lesions in NC/Nga Mouse
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이남열(대전대학교); 김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives The purpose of this study is to investigate the effect of JUJSTK on atopic dermatitis in an in-vitro experiment using an NC/Nga atopic dermatitis mouse, which has histological and clinical similarities to the humans in terms of health condition. Methods We evaluated IL-1β, IL-6, IL-10, TNF-α mRNA, TGF-β mRNA, CD4+/IFN-γ+ and IL-17+CD4+ Th17 cells of NC/Nga atopic dermatitis mouse by real-time PCR and intracellular staining in vitro. Results JUJSTK medicines supressed the activities of IL-1β, IL-6, TNF-α, TGF-β mRNA and IL-17+CD4+ Th17 cells and it incresed the activities of IL-10 mRNA in B cells. The level of CD4+/IFN-γ+ in T cells were increased by JUJSTK. Conclusions JUJSTK on atopic dermatitis might be incredibly effective to the atopic dermatitis treatment.
한의학
null
kci_detailed_000248.xml
ART001372982
oai_dc
아토피樣 피부염 NC/Nga생쥐에서 加減消毒飮과 아토피크림-紫雲膏의 병용투여가 피부염에 미치는 영향
Effects of Concurrent Administration of KKSDU and AJ on Atopic Dermatitis-like Skin Lesions in NC/Nga Mouse
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "송현지(대전대학교); 김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives The purpose of this study is to investigate the effect of concurrent administration of KKSDU and AJ on atopic dermatitis in an in-vivo experiment using an NC/Nga atopic dermatitis mouse, which has histological and clinical similarities to the condition in humans. Methods We evaluated clinical skin score, hematology, serum total IgE and IgG1 of NC/Nga atopic dermatitis mouse and analyzed the cytoline level, total cell number, immunohistochemical staining, histological features of axillary lymph node(ALN), draining lymph node(DLN), peripheral blood mononuclear cells(PBMCs) and dorsal skin tissue in NC/Nga mouse. Results Orally administration of KKSDU and concurrent administration of KKSDU and AJ decreased the clinical skin score, total cell number of WBC, platelet, neutrophils, eosinophils in blood, serum total IgE & IgG1, IL-5, IL-13. Also, total cell number of ALN and dorsal skin tissue, absolute cell number of CD3e+&CD19+, CD4+&CD8+, CD3+/CCR3+, CCR3+, CD3+/CD69+, CD3+/CXCR5+ in ALN, PBMCs, absolute cell number of CCR3+, CD3+/CD69+, CD11b+/Gr-1+ in dorsal skin tissue, Eotaxin2 mRNA, CCR3 mRNA in dorsal skin tissue and gene expression of IL-5 mRNA, IL-13 mRNA in ALN are significantly decreased. Furthermore, thickness of epidermis, infiltrated inflammatory immune cell & mast cell in dermis, histologic infiltration of mast cell, the size of inflammatory lymphocytes cells & plasma cells in ALN and histologic infiltration of CD4+ & CCR3+ in ALN and dorsal skin tissue are significantly decreased. However, total cell number of DLN, absolute cell number of CD3+&CD19+, CD4+&CD8+, B220+/CD23+, CD3+/CD69+ in DLN and CD4+CD25+foxp3+ Treg cell, foxp3 mRNA in dersal skin tissue are increased significantly. Conclusions Concurrent administration of KKSDU and AJ on atopic dermatitis in an in-vivo experiment using an NC/Nga atopic dermatitis mouse was very effective to the atopic dermatitis treatment.
한의학
null
kci_detailed_000248.xml
ART001372990
oai_dc
체성분 분석과 골연령 측정을 통한 취학 전 아동의 성장에 대한 임상연구
A Clinical Study on Growth of Children Based onAnalyzing Body compositions And Measuring Bone Age
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "윤혜진(대구한의대학교); 이유진(대구한의대학교); 백정한(대구한의대학교)" ]
Objectives The purpose of this study is to have better data and to make efficient clinical reviews on pre-school children's growth based on two measurements; Body composition for measuring body volume and bone age for potential growth. Methods The study was conducted with 221 children(118 of boys and 103 of girls) from three kindergartens. Body compositions(soft lean mass, body fat mass, percent body fat) were measured by bioelectrical impedance analysis, bone age was measured by bone density through ultrasonic image of calcaneus. Results and Conclusions 1. The higher level on weight or BMI, the more averages of soft lean mass, body fat mass, percent body fat. 2. The average bone ages and bone age-chronological age were lower in under 50 percentile's group, but it was higher in upper 50 percentile's group. Also, children with high BMI had older in bone ages and bone age-chronological age. 3. The higher in height percentile based on the bone age; there were more soft lean mass. 4. The averages of bone age and bone age-chronological age were significantly decreased, the more percentiles of height according to bone age were big, they were higher than total average in under 50 percentile's group of height, lower than total average in over 50 percentile's group of height in both boys and girls. 5. The average of MPH were significantly decreased in top percentiles of children's height distribution. Also, in the upper percentiles of height distribution based on bone age were big in only boys. 6. The body compositions(soft lean mass, body fat mass, percent body fat) were related to body volume growth, which can be measured by weight or BMI. The bone age, bone age-chronological age, and MPH were related in terms of hight. The body volume growth was a little bit related with potential growth.
한의학
null
kci_detailed_000248.xml
ART001373001
oai_dc
성동구내 어린이집 어린이의 수면 및 식생활 실태와성장과의 관련성에 대한 보고
A Study on the Relations between Growth and the Current Conditions of the Day-care Center Children’s Sleeping Patterns and Diet patterns in Seongdong-district
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "박유진(제인한방병원); 윤지연(제인한방병원)" ]
Objectives The purpose of this study is to examine sleeping patterns and diet patterns of the children in day-care centers in Seongdong-district and to find out the relationships between those two patterns and children growth. Methods 686 day-care center kids participated in the examination. We measured their heights and weights. We also conducted a questionnaire survey (of them) on their sleeping patterns and diet patterns. Based on the findings, we have analyzed correlations of the factors. Results 1. We have interviewed 686 children in day-care centers in Seongdong-district. Substantial survey was conducted to 672(14 kids didn’t go through regular medical checkups). Their age ranged from 4 months to 120 months and weights covered from 6.20 kg to 50.80 kg with the average of 16.97kg. Their height ranges were from 70.4cm to 140.6cm and the average was 100.76cm. 2. The survey results showed that birth-height affects children’s current height. The results from the group of age over 25months and the group covering 2 to 6 years indicated that birth-height affected the current height as well. However, the result from the age group over 37 months showed that birth-height didn’t relate to the current height. 3. Results from questionnaires on sleeping patterns indicate that children sleeping longer are taller than the other. Results of other questionnaires showed no substantial relations to height. 4. Results from questionnaires on diet patterns, cold food eating habit affects growth. Conclusions According to the results above, sleeping patterns substantially affects the growth. In order to find out, however, the specific relations between them, further research would be necessary.
한의학
null
kci_detailed_000248.xml
ART001372980
oai_dc
NC/Nga 생쥐에서 加味淸心蓮子湯의 GATA-3 조절에 의한항아토피 피부염 효과
Anti-dermatitis Effects of KamiCheongsimyeonjatang on GATA-3 Regulation in NC/Nga Mouse
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "박슬기(대전대학교); 김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives The purpose of this study is to investigate effectiveness of KamiCheongsimyeonjatang (KCSYJT) medicines to suppress atopic dermatitis in mouse model experimentally. Methods First, in vitro, we isolated B cells from 18 weeks of atopic dermatitis-like skin NC/Nga mouse. Then we analyzed FACS(Fluorescence Activated Cell Sorter)by intracellular staining of IFN-γ, GATA-3+ and analyzed cytokines by using real-time PCR. Secondly, in vivo, after administration of KCSYJT to atopic dermatitis NC/Nga mouse at 12 weeks of age, we analyzed serum IgE and the change of activated cell in PBMCs(Peripheral Blood Mononuclear Cells). Results In vitro, KCSYJT medicines supressed IL-1β, IL-6, TNF-α, and TGF-β mRNA and increased IL-10 mRNA in B cells. Also, KCSYJT medicines decreased the levels of GATA-3⁺CD4⁺ and increased the levels of IFN-γ⁺CD4⁺ in CD4⁺ T cell. In vivo, serum IgE levels decreased in KCSYJT group than control group and In PBMCs, the activated cell percentage of granulocytes, CD3+, CD3+/CD4+, B220+/CD23+, and CCR3+ decreased and CD19+, CD3+/CD8+ increased in KCSYJT group than control group. Conclusions This study demonstrates immunological activity of KCSYJT on atopic dermatitis-like model mice.
한의학
null
kci_detailed_000248.xml
ART001372965
oai_dc
아토피 피부염 환아에 대해 3G 색과 원문양의 시각적 활용이 증상변화에 미치는 영향에 관한 임상연구
Clinical Study for Visual Application of Circle Pattern with 3G Color on Atopic Dermatitis Patients
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "최현(함소아한의원); 김정신(함소아한의원); 이은혜(함소아한의원네트워크)" ]
Objectives Several emotional therapies are reported to be effective in reducing the severity of atopic dermatitis (AD). The aim of this study was to assess the effect of color and pattern on the severity of AD and the quality of life in young AD patients. Methods We randomly assigned 41 children into case and control groups and had them participate in 15-minute block play sessions once in a week. The case group used blocks with green (3G, Munsell Color System) circle patterns on it, while the control group played with plain white blocks. We also provided a set of playing cards with the corresponding patterns. This trial continued for 4 weeks and 36 children (87.8%) completed. The primary outcome measurement was the Scoring Atopic Dermatitis (SCORAD) index. We also built a quality of life (QOL) questionnaire by modifying Infant-Dermatology Life Quality Index (IDLQI). SCORAD and QOL were evaluated on every visit. Results After the trial, SCORAD score decreased significantly both in case and control groups. (34.5±13.3 to 19.8±15.7; 33.8±12.4 to 23.5±10.6) However, there was no significant difference in the change of total score between two groups. (p=0.2674) Among items of SCORAD, pruritus and sleep loss showed greater reduction in case group. (p=0.0195; p=0.0482) The improvement of QOL was shown to be greater in case group than in control group. (19.6±7.4 to 10.7±9.0; 19.6±6.3 to 17.0±4.5) Conclusions Repeated exposure to green circle pattern reduced pruritus and sleep loss and improved QOL in children with AD. Proper visual stimuli are probably helpful for pediatric AD.
한의학
null
kci_detailed_000249.xml
ART001373003
oai_dc
吉益東洞의 저술에 나타난 結實而拘攣에 대한 考察 -吉益東洞의 ≪藥徵≫을 중심으로-
A Study on Caking Muscular Contraction(結實而拘攣) Based on the Research of Yakucho (藥徵)
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김동진(동국대학교); 김장현(동국대학교)" ]
Objectives Paeonia lactiflora Pall(芍藥) is known for curing caking muscular contraction(結實而拘攣) according to Yakucho(藥徵) published by Yoshimasu Todo(吉益東洞), but the descriptions of caking muscular contraction(結實而拘攣) are not fully provided. Methods In order to further investigate and review the exact meaning of caking muscular contraction(結實而拘攣), present study has been conducted on the basis of researches of Yoshimasu Todo's literatures, focusing on Yakucho. Results As a result of wide range of investigation, it is concluded that caking muscular contraction(結實而拘攣) indicates an abnormal muscular contraction of rectus abdominis. Conclusions This study will provide helpful clinic information to doctors who will apply medical treatment specified in Yoshimasu Todo's Yakucho(藥徵) to patients in the future.
한의학
null
kci_detailed_000249.xml
ART001372996
oai_dc
성장클리닉에 내원한 소아의 골연령과 체성분 및 신체 계측치의 상관성에 대한 연구
A Study on Relationships between Bone Age and Body Composition
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이유진(대구한의대학교); 윤혜진(대구한의대학교); 백정한(대구한의대학교); 곽민아(대구한의대학교)" ]
Objectives The purpose of this study was to examine relationships between bone age and body composition to make efficient clinical reviews on children’s growth. Methods 157 of children in age of 3 years to 16 years old were participated in this study(88 of boys and 69 of girls). They visited the department of pediatrics, ○○ university oriental hospital and were measured their body composition and bone age. Results 1. An age and bone age, height, weight, and body mass index were positively correlated, and also a bone age and height, weight, and body mass index were positively correlated. 2. The level of soft lean mass, body fat mass, and MPH were increased in boys in higher height percentile. Children's predicted adult height was higher in children in higher height percentile. 3. The level of body fat mass was increased as weight percentile increased. Bone age, MPH was increased as weight percentile increased, especially in case of boys. In girl's case, the level of soft lean mass, their predicted adult height, the difference between children's bone age and their actual age was increased as weight percentile increased. Conclusions Measuring bone age and body composition is the effective way to estimate children's growth and development in future.
한의학
null
kci_detailed_000249.xml
ART001372985
oai_dc
成長補中健兒湯 투여가 소아의 신장 성장에 미치는 효과
Effects to the Growth after Administration of Seongjangbojunggeonatang
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "유현영(동국대학교); 민상연(동국대학교); 김장현(동국대학교); 김기봉(동국대학교)" ]
Objectives The purpose of this study is to determine the effects of Seongjangbojunggeonatang treatment on the growth of children. Methods This study was conducted with the 121 children in age of 6 to 14 years old who visited the Department of Pediatrics, Oriental Hospital in Seongnam-si, Gyeonggi-do, Korea. We measured height at the first time visit, and after 12 months. The data we collected were analyzed based on the standards growth chart, 2007. Results 1. The mean heights of 6 to 11 year-old boys after administration of Seongjangbojunggeonatang were significantly higher compared to normal average height (p<0.01). The mean heights of 12 to 13 year-old boys after administration of Seongjangbojunggeonatang were significantly higher than normal average height (p<0.01). The mean heights of 14 year-old boys after administration of Seongjangbojunggeonatang were significantly higher than normal average height (p<0.05). 2. The mean heights of 6 to 9 year-old girls after administration of Seongjangbojunggeonatang were significantly higher than normal average height (p<0.01). The mean heights of 10 to 11 year-old girls after administration of Seongjangbojunggeonatang were significantly higher than normal average height (p<0.05). The mean heights of 12 to 14 year-old girls after administration of Seongjangbojunggeonatang were significantly higher than normal average height (p<0.05).
한의학
null
kci_detailed_000249.xml
ART001372979
oai_dc
Risk Factors for Sleep Bruxism in the Children
Risk Factors for Sleep Bruxism in the Children
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "박은성(경희대학교); 이진용(경희대학교)" ]
Objectives Sleep bruxism has a great effect on the patient's quality of sleep, and it is expected to be associated with a lot of disorders. Especially, for children, sleep is closely relative to the children's growth and their development. Therefore, sleep bruxism should be carefully treated. Compare to its importance, the risk factors in sleep bruxism for children are not fully studied. Methods Parents were participated this study by answering some of questions from Stanford Sleep disorder clinic, Tucson Children's Assessment of Sleep Apnea (TuCASA) and Sleep-EVAL knowledge system. Total 604 children were surveyed for this study and they were divided into two groups group of children with and without bruxism. Results In sleep disorder, snoring, sleep talking and sleep apnea were at risk. And with GI disease field, indigestion, stomachache, halitosis, gas, coated tongue were refered as risk factors. Children who have allergy disease, specially rhinitis, were at greater risk and plantar fever, stomatitis were risk factors, too. And they also reported irritability, anxiety, sensitivity disorders more frequently than the no-tooth-grinding group. Conclusions We can find that snoring, sleep talking and sleep apnea, indigestion, stomachache, halitosis, gas, coated tongue, allergy disease, plantar fever, stomatitis, irritability, anxiety, sensitivity disorders were associated to sleep bruxism. Most of all, the factor most closely related to sleep bruxism is allergy rhinitis.
한의학
null
kci_detailed_000249.xml
ART001372988
oai_dc
자폐증의 鍼치료에 대한 임상 연구 고찰 -최근 중의학 임상 연구를 중심으로-
Clinical Trial Study on Acupuncture for Autism Based on the Current Traditional Chinese Medical Journals
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김윤영(동국대학교); 민상연(동국대학교); 김장현(동국대학교)" ]
Objectives The purpose of this study is to investigate the current acupuncture treatment of autism. Methods 13 Chinese clinical studies published in the last five years were selected for analyzing. Results Treatment methods were used; massage of acupoints, electro acupuncture, scalp acupuncture, the general acupuncture and special acupuncture treatments for autism as Jin's three needling, Intelligence-increasing acupuncture. Commonly used acupoints were sishencong(四神總), shenting(神庭), benshen(本神), yintang(印堂), naohu(腦戶), naokong(腦空), bohui(百會), neiguan(內關), yanyu1qu(言語1區), yanyu2qu(言語2區), yanyu3qu(言語3區). 10 studies were showed the effects of acupuncture with total improvement rate and 7 of them were higher than 80%. Also, most of the studies showed the acupuncture treatment was extremely effective in improving autism children's speaking ability. Conclusions Acupuncture have been shown as an effective treatment on autism. Further studies about various treatment using by acupuncture and the evaluation standard would be needed.
한의학
null
kci_detailed_000249.xml
ART001233267
oai_dc
加味羌活散이 집먼지 진드기 추출물로 유도된 NC/Nga mouse의 아토피 피부염에 미치는 영향
Effect of Kami-kanghwalsan(KKHS) on Atopic Dermatitis-like Skin Lesions Induced in NC/Nga Mouse by Mite Antigen Stimulation
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김윤희(대전대학교); 한재경(대전대학교)" ]
Objectives The purpose of this study is to investigate the effect of KKHS on atopic dermatitis in an in-vivo experiment using an NC/Nga atopic dermatitis mouse, which has histological and clinical similarities to this condition in humans. Methods To investigate the effect of KKHS on atopic dermatitis (AD), we evaluated atopic dermatitis-like skin lesions by clinical skin index and analyzed immunological parameters in peripheral blood mononuclear cells(PBMCs), splenocytes, draining lymph node(DLN) and performed skin histology in ears and dorsal skin of atopic dermatitis of NC/Nga mouse in vivo. Results In vivo, clinical skin severity score was significantly lower in the KKHS group than in the control group. IgE, IL-6, TNF-α, IgM, IgG2a and IgG2b levels in serum decreased remarkably in the KKHS group than in the control group, and the level of IFN-γ production which is secreted from Th1 cell was increased by KKHS. After this experiment we analyzed immunological cells (CD3+, CD19+, CD4+, CD8+, CD3+CD69+, CD4+CD25+ and CD49b+) by flow cytometry. It results that the total absolute number of CD3+, CD19+, CD4+ and CD8+ cells were recovered as much as normal state, and the level of CD3+CD69+ in isolated DLN and PBMCs were significantly decreased, and total absolute number of Gr-1+, CD11b+ and CD3+ in dorsal skin of NC/Nga mouse were decreased by KKHS. We analyzed ear, DLN, and neck-back skin after biopsy and dyeing by hematoxyline/eosin(H&E), toluidine staining (mast cells marker). KKHS were very effective to the histological symptoms which are in dermal and epidermal thickening, hyperkeratosis and inflammatory cell infiltration. Ear thickness was significantly decreased compared with the control group and the size of inflammatory lymphocytes cells (ILC) and plasma cells (PC) in DLN were also decreased. Conclusions KKHS on atopic dermatitis in an in-vivo experiment using an NC/Nga atopic dermatitis mouse was very effectiveness to the atopy dermatitis treatment.
한의학
null
kci_detailed_000249.xml
ART001233268
oai_dc
天麥湯이 항알러지 염증반응에 미치는 영향
Anti-allergic Effects of Cheonmaec-tang in RBL-2H3 Cell
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "김용현(동의대); 김원일(동의대학교); 이승연(동의대학교)" ]
Objectives The purpose of this study was to examine the anti allergic reaction with Cheonmaec-tang. Methods We examined Cell Viability, β-hexosaminidase, TNF-α, IL-4 secretion from RBL-2H3 cell after pre- treatment with 2 ㎎/㎖, 4 ㎎/㎖ of Cheonmaec-tang. Results We observed that Cheonmaec-tang is reduced to β-hexosaminidase, TNF-α, IL-4 secretion in RBL-2H3 cell. Conclusions These results indicate that Cheonmaec-tang has anti-histamic effect and controls TNF-α, IL-4 secretion on allergic reaction.
한의학
null
kci_detailed_000249.xml
ART001235418
oai_dc
외상성 뇌경색 환아 1례에 대한 증례보고
A Case Report of Traumatic Cerebral Infarction
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이남열(대전대); 김윤희(대전대학교); 한재경(대전대)" ]
Objectives This study is to investigate the effects of oriental medical treatment for traumatic cerebral infarction. Methods We treated the patients with herbal medicine, acupuncture, aroma therapy, rehabilitation, and we evaluated these cases with Activity Index. Results There are some improvements in each patients, such as manual muscle power, finger apraxia after oriental medical treatments. Conclusions We report a change for the better effect of oriental medical treatment on this case. The more clinical studies of oriental medical treatment for traumatic cerebral infarction are needed.
한의학
null
kci_detailed_000249.xml
ART001235434
oai_dc
性早熟證에 관한 연구의 최근 동향 -최근 중의 잡지를 중심으로-
The Study for Precocious Puberty in Recent Journals of Traditional Chinese Medicine
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이민정(경희대학교); 장규태(경희대학교); 한윤정(경희대학교)" ]
Objectives The aim of this study was to investigate the treatment of precocious puberty in current traditional Chinese medical journals. Methods To figure out diagnosis methods, treatment methods, treatment effects of oriental medicine about precious puberty, Chinese medical journals from China National Knowledge Infrastructure (CNKI) which was published from 1999 to 2007 were analyzed and precocious puberty was also been searched. Results 82 articles were selected. 1.Yin and purging Fire(滋陰瀉火) from traditional Chinese Medicine was usually used. 2.The herbs were almost used such as Rehmannia glutinosa(地黃), Anemarrhena asphodeloides (知母), Phellodendron amurense(黃柏), Thesium chinense(夏枯草), Paeonia suffruticosa Andrews(牧丹皮), Alisma canaliculatum(澤瀉), Testudinis Plastrum(龜板), Paeonia japonica(白芍藥), Bupleurum falcatum(柴胡), Genianae Scabrae Radix(龍膽草). 3.The total improvement rate was 72.50 to 100% Conclusions The oriental medical treatments for precocious puberty were presumed to be effective, but more studies are still needed.
한의학
null
kci_detailed_000249.xml
ART001235139
oai_dc
生血潤膚飮을 이용한 아토피 피부염 치험례 보고
Case Study of the Effects of Saenghyeoryunbueum on Atopic Dermatitis
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "유현영(동국대); 민상연(동국대학교); 김장현(동국대학교); 김기봉(부산대학교)" ]
Objectives The purpose of this study is to report the clinical effects of herbal medicine on atopic dermatitis. Methods This nine clinical studies were done by those people who were visited the Oriental Hospital and all of them were diagnosed as atopic dermatitis. We treated the atopic dermatitis patients with herbal medicine(Saenghyeoryunbueum), and we checked SCORAD score and observed the wounds those patients had. Results The patients' wounds were improved and SCORAD score was decreased. Conclusions Herbal medicine(Saenghyeoryunbueum) is an effective in the treatment of atopic dermatitis, and it helped to improve regenerating the skin in the body. The further studies might be also needed.
한의학
null
kci_detailed_000249.xml
ART001233271
oai_dc
益黃散이 methotrexate로 誘發된 흰쥐의 免疫機能低下에 미치는 影響
The Effect of Ikhwang-San on Immunosuppression Induced by Methotrexate in SD Rats
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "박유부(대구한의대); 백정한(대구한의대학교); 윤혜진(대구한의대)" ]
Objectives This study is to investigate how dose Ikhwang-San can be effective on SD rats which deteriorated immunity caused by methotrexate. Methods The test sample were dosed once a day for 14 days by gastric gavage at the beginning of dosage 1000, 500 and 250㎎/㎏/10㎖ from 2 days after last MTX-dosing, and the changes of the body and spleen weight, total number of blood leukocytes , total number of lymphocytes, the percentage of B-cell, T-cell, CD3+CD4+ T-cell, CD3+CD8+ T-cell and CD4+/CD8+ T-cell ratios in the blood and spleen were observed. Results The changes of the body and spleen weight, the total number of blood leukocytes, the total number of lymphocyte in the blood and spleen were significantly increased in IHS Extracts groups comparing with the control group. The percentage of B-cell, T-cell, CD3+CD4+ T-cell in the blood and spleen were significantly increase in IHS groups and comparing with the control group. The ratio of CD4+/CD8+ T-cell in blood and spleen was significantly increased in IHS Extracts groups comparing with the control group. Conclusions According to those results, Ikhwang-San has good immunostimulating effect on SD rats which had deteriorated immunity caused by methotrexate.
한의학
null
kci_detailed_000249.xml
ART001235138
oai_dc
한방소아과 설문지 및 검사에 관한 임상현황연구
Clinical Investigation of Survey and Test in Korean Oriental Pediatrics
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "황영준(동국대); 민상연(동국대학교); 김장현(동국대학교); 김기봉(부산대학교)" ]
Objectives The purpose of this study is to investigate whether Korean oriental pediatrics hospitals are using their feedback surveys to improve their medical conditions. Methods We selected 24 oriental medicine university hospitals and sent surveys to investigate. 15 of those surveys were analyzed. Results The results were classified as follows; Only 9 of university hospital said that they are currently using their feedback surveys to improve their services. Question for asking the purpose of doing their feedback surveys, 58.3% of hospital responded to get some information for diagnosis, 25% of them said to see the progress of treatment of specific disease, and 16.7% answered for using their data to the further studies. The question about the reason why hospital were need to make these feedback surveys, 46.2% of them answered to apply better service, 38.4% of them said to post medical journal. The question for asking what do oriental medical hospitals check from feedback surveys, 40% of them said they check Ryodoraku, 33.3% was pulse diagnostic apparatus, EAV(Electro-puncture According to Voll) was 26.7%. The classification according to purpose of test resulted as follows; information for diagnosis was 48.1%, the progress of a disease was 37.3%. In addition oriental medical test there were blood test, radiological test, brain waves test, Hair Tissue Mineral Analysis(HTMA), ultrasonic test, body composition analysis. Conclusions Further clinical research is necessary for improvement of using the feedback survey effectively.
한의학
null
kci_detailed_000249.xml
ART001233269
oai_dc
升葛湯의 제형변화에 따른 항알레르기 효과의 비교 연구
The Comparative Study on the Difference of Anti-allergic Effects Based on Different form of Seunggal-tang
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이승연(동의대학교); 강경화(동의대학교); 유선애(동의대학교); 류지효(동의대학교); 이해웅(동의대학교); 김흥배(동의대)" ]
Objectives Seunggal-tang is one of the prescriptions of oriental herbal medicine, which has been applied to several allergic diseases such as atopic dermatitis. This study was planned to compare differences of anti-allergic effects based on different form of Seunggal-tang by manufacturing differently. Methods Two types herb medicine products were used; aqueous extract (SG-T, Seunggal-Tang) and powder (SG-S, Seunggal-San) which were made from the same mixed formula of Seunggal-tang. To investigate in vitro anti-allergic activities, rat basophilic leukemia (RBL-2H3) cells were treated with SG-T and SG-S for 1 hour, and then stimulated with the phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore A23187. We examined the release of beta-hexosaminidase, as a marker of degranulation, and the releases of tumor necrosis factor (TNF)-alpha and interleukin (IL)-4, as proinflammatory cytokines. Results SG-T and SG-S didn’t have effects on cell viabilities in concentrations under 2㎎/㎖. In additionto that, SG-T more inhibited releasing β-hexosaminidase, TNF-α and IL-4 than SG-S. Conclusions These results indicate that SG-T is more effective against mast cell-mediated allergic reactions than SG-S.
한의학
null
kci_detailed_000249.xml
ART001235135
oai_dc
정신지체에 대한 한의학 치료와 연구 동향(2003-2007년 중국 임상 논문에서)
Traditional Chinese Medicine in the Treatment of Mental Retardation : A Review Stud
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "임정균(우석대); 김락형(우석대학교)" ]
Objectives This study was designed to analyze the clinical studies on Mental retardation(MR) in traditional Chinese medicine(TCM). Methods For this study, we searched the clinical studies on MR, which had been published from 2003 to 2007, through web site CNKI(中國知識基礎設施工 http://www.cnki.net). There were 17 clinical studies and we focused on those studies. Results 1. In those Chinese studies, they used following words to describe Mental retardation; 小儿弱智(xiǎoérruòzhì), 智能發育不全(zhìnéngfāyùbuquán), 智力低下(zhìlìdīxià), 精神發育遲滯(jīngshéfāyùchízhì), 智能落后(zhìnéngluòhòu), 智能遲緩(zhìnéngchíhuǎn), 先天愚型患儿(xiāntiānyúxínghuàn’ér). 2. There were many kinds of TCM treatment methods for MR, such as herbal medicine, acupuncture, electroacupunture, acupoint injection, Chuna therapy, and special education. And those TCM treatments methods showed higher efficacies in the treatment of MR compared with Western medicine. 3. Mental retardation was related with the deficiency of heart, kidney, liver, spleen(心虛, 腎虛, 肝虛, 脾虛) and the pathological mechanism of Phlegm(痰) and Blood stasis(瘀血)in the studies about the Bian Zheng-the types of differential diagnosis- of MR. 4. Most of studies used Intelligence Quotient(IQ) to assess the efficacy of TCM treatment of MR. And the duration of treatment, the degree of illness, the age of patient, and the cause of illness affected the prognosis of MR. Conclusions These results suggest that traditional medicine could be one of the useful treatments on MR. And these results could be used in the clinical practices and studies on MR in Korea.
한의학
null
kci_detailed_000249.xml
ART001233272
oai_dc
멀미의 病因에 대한 韓醫學的 接近
The Cause of Motion Sickness in Oriental Medicine
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "한윤정(경희대학교); 장규태(경희대학교)" ]
Objectives The purpose of this study is to investigate that causes of motion sickness in oriental medicine. Methods The internal and external studies about motion sickness were searched Results and Conclusions The motion sickness is induced by conflict of balance system including vestibular, visual and proprioceptive system. The motion sickness is more common in female and in children between 2 and 12 years old. In western medicine, antihistamine and anticholinergic has been used for treatment of motion sickness, but these anti-motion sickness drug turn out to be not a perfect solution and have several side effects. On the other hands, In oriental medical terminology, there is no words equivalent to the “motion sickness”, but we consider the motion sickness as state with dizziness, nausea and vomiting. The motion sickness can be induced by either internal or external causes and the internal causes can thought to be a constitutional factor of an individuals, and the general transportation can be an external cause. The important internal cause is a dysfunction of the spleen, stomch(脾胃不調), retention of phlegm and fluids(痰飮), and deficiency of the kidney jing(腎精不足). The wind(風) and fire(火) in the upper part of the body, especially in the head, also can be an important cause of the motion sickness.
한의학
null
kci_detailed_000249.xml
ART001235130
oai_dc
至聖保命丹의 抗痙攣 작용에 관한 실험적 연구
An Experimental Study on the Anticonvulsive Effects of Jisungbomuyngtan
{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }
[ "이희성(경희대학교); 김덕곤(경희대학교)" ]
Objectives In order to investigate the anticonvulsive effects of Jisungbomuyngtan, the experiments were done in mice. Methods After solid extracts of Jisungbomuyngtan was orally administered to mice, four types of convulsion were induced in mice by ECT, strychnine, picrotoxin, caffein. Each of the time to convulsion and death was measured. Results 1. The solid extracts of Jisungbomuyngtan showed a remarkable effect in delaying the onset of convulsion induced by ECT 2. In case of convulsion induced by strychnine, the solid extracts of Jisungbomuyngtan revealed a slight, but not statistically significant effect. 3. Considerable prolongation of time to death was observed in convulsion induced by picrotoxin due to the anticonvulsive effect of Jisungbomuyngtan. 4. The anticonvulsive effect of Jisungbomuyngtan was not found in convulsion induced by caffein. Conclusions Jisungbomuyngtan effect remarkably in delaying the onset of convulsion induced by ECT. But slightly effect by strychnine. And Jisungbomuyngtan effect in prolonging time to death in convulsion induced by picrotoxin, but not found in convulsion induced by caffein.
한의학
null
kci_detailed_000249.xml