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ART001659308	oai_dc	Error Correction in Pedagogical Context	Error Correction in Pedagogical Context	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "우수정(건양대학교)" ]	The activity of correction is prevalent and important in the context of language teaching and learning since the correction is closely related to the work of teaching. This paper explores correction sequences in a pedagogical context to examine how the teachers design their correction relevant turns. In the activity of correction, two distinct actions are involved: locating an error and replacing the error with what is correct. Using conversation analytic framework, it is observed that the teachers in the study use linguistic resources when locating errors, and this task can be accomplished successfully when the interlocutors work together and build common understanding on what the "matter-of-focus" (Brouwer, 2004) is in ongoing conversation. In doing to correcting, the teachers use several strategies to make the correction less-face-threatening and less salient so that the other purpose of the talk, teaching, can be focused.	언어학	null	http://dx.doi.org/	kci_detailed_000246.xml
ART001659309	oai_dc	Information Features Coded Through Epistemic Modal Suffixes	Information Features Coded Through Epistemic Modal Suffixes	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "양창용(제주대학교)" ]	The main purpose of this paper is to explain Korean final sentence ending in terms of information structure. Based on Lee's(1991) argument, this paper focuses on the functional understanding of modal suffixes. Traditionally, the category of modals do not represent all the different attitudes of a speaker toward the proposition and the hearer. Instead, it is known to fulfill two functions: mood and speech register and group according to different moods. With this in mind, the present study tries to show that information status coded by the ending suffixes should be distinguished from the status of modality. In analyzing the ending suffixes, the informational functions should be regarded as a basis for further understanding of modality	언어학	null	http://dx.doi.org/	kci_detailed_000246.xml
ART001659307	oai_dc	A Discourse-analytic Study of Judges’ Interruptions in Korean Courtroom Trials	A Discourse-analytic Study of Judges’ Interruptions in Korean Courtroom Trials	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이지은(이화여자대학교)" ]	With the courtroom examination taking center stage in the Korean criminal court procedure, a development which is believed to enhance transparency and fairness in court system, a discourse- based study can provide information on the discursive and professional practices of legal professionals. Drawing on the discourse of criminal courtroom interactions in Korea, this paper examines the phenomenon of trial judges’ interruption and its various functions in courtroom trials. Interruptions can be largely divided into cooperative interruption and non-cooperative interruption, but a closer look reveals that judges’ interruption during courtroom proceedings can be seen as part of collaboration and confrontation in the judge’s fact-finding activities, and it demonstrates the judges’ active role in conducting courtroom trials in an efficient and fair way.	언어학	null	http://dx.doi.org/	kci_detailed_000246.xml
ART001659314	oai_dc	TEACHERS’ AND LEARNERS’ PERSPECTIVE ON USING ENGLISH LANGUAGE MOVIES IN THE LISTENING CLASS	TEACHERS’ AND LEARNERS’ PERSPECTIVE ON USING ENGLISH LANGUAGE MOVIES IN THE LISTENING CLASS	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "양지영(제주대학교)" ]	Since English has become a international language in the world, English education in Korea has focused on communicative competence. However, it is questioned that the listening part of English textbooks has effects on enhancing listening ability which can use in real communicative contexts. In this study, it will be shown that the adequacy of English movies as an authentic listening teaching materials and teachers' and students' perspectives on using the English language movies in the listening class will be discussed.	언어학	null	http://dx.doi.org/	kci_detailed_000246.xml
ART001659312	oai_dc	영어교사 수업능력 향상을 위한 교육대학원 영어교육전공 교과과정 개선방안		{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "임정완(대구대학교)" ]	The purpose of this study was to propose an alternative curriculum for English education major in the graduate schools of education to improve the teaching ability of teachers of English. This study surveyed high school English teachers' opinions about the quality of being a good English teacher and his/her teaching ability. A total of 42 teachers working in Seoul or Daegu participated in this study. The results were as follows: First, the most important factors of being a good English teacher were being able to use English teaching methods which were appropriate to the current level of learners' proficiency, to make a good lesson plan and use it with various teaching materials to stimulate their students' motivation for learning, to communicate well in English, to have good English reading and writing skills, to have sound personality, a sense of educational duty, and ethics. The least important factors, on the other hand, for being a good teacher of English were having pedagogical content knowledge such as English literature and phonetics as well as using computer assisted language teaching and participating to teacher training and voluntary service. Based on the findings, the curriculum of a particular graduate school of education in Daegu was investigated and some suggestions were made for improvement on the curriculum.	언어학	null	http://dx.doi.org/	kci_detailed_000246.xml
ART001659311	oai_dc	일본어 조건표현「と,ば,たら,なら」의 담화적 기능 -반복표현과 초점화를 중심으로-	A Functional Approach to Japanese Conditional Expressions ‘To, Ba, Tara, and Nara’	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "고용진(제주한라대학교)" ]	The present paper deals with the linguistic repetition and focus phenomenon in the Japanese conditional expressions such as to, ba, tara and nara. It is suggested that linguistic repetition plays an important role in everyday conversation and has an important discourse function. Its main role is not just a lengthy stretch of discourse but a contribution of smooth flow of discourse. In addition, repetition is known as a focus device to connect old information to new information. This is because repetition has something to do with the participants' roles in choosing the given information over new information or vice versa in the smooth flow of discourse.	언어학	null	http://dx.doi.org/	kci_detailed_000246.xml
ART001659315	oai_dc	「朝顔」의 의미론 - 일본고전 작품을 중심으로-		{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "최진희(경일대학교)" ]	本稿は『万葉集』『八代集』『源氏物語』『伊勢物語』『枕草子』に表われる「朝顔」のイメージと、その解釈についての考察である。花のイメージから出てきた意味として捕えれている点が多いということがわかる。特に、桔梗(ききょう)․牽牛子朝(けにごし)(=今の赤顔)の解釈が目立ち、現代語として「朝顔」が一番近い解釈であったのがわかる。でも、言葉の解釈より、花のイメージから出てきた意味として使われていた点に注目したい。それは「恋の軽率・妻・虚しさ・切なさ」などと挙げられるが、恋との関わりの深い「朝顔」の意味が多かったのがわかる。それが中世になっていくにつれて「朝顔」の意味はどうなっていくのだろうか。平安時代からも「恋の移り気のはやさ」「虚しさ」などの意味もあったけれども、とくに後代に流れていく作品の中でのイメージはどうなっていくのであろうか。そのように移っていく意味の考察を、作品を通して探っていくのを今後の課題としておきたい。	언어학	null	http://dx.doi.org/	kci_detailed_000246.xml
ART001659316	oai_dc	翻訳における異文化コミュニケーションのあり方　一学部課程における翻訳教育の事例を中心にー		{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "신장호(대구외국어대학교)" ]	At the present moment, the translation education at the level of university focuses on dealing with language skills rather than upgrading the translation skills or intercultural understanding. Therefore, it is limited to the literally oriented semantic transfer not considering multiple aspects of translation. It is desired that for various cultural aspects should be taken into consideration in the education of translation. This kind of socio-cultural aspects in translation will help produce the better translator in the future.	언어학	null	http://dx.doi.org/	kci_detailed_000246.xml
ART001659313	oai_dc	예비초등교사용 TEE 인증 평가 개발		{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "홍경선(제주대학교); 양효선(제주대학교부설초등학교); 이재영(제주대학교); 한계련(노형초등학교)" ]	The purpose of this study is to develop an assessment program for TEE(Teaching English In English) qualification of the students in teachers college at Jeju National University in order to improve their English proficiency and teaching skills. This TEE qualification program was designed on both pre-service and in-service teacher needs analysis; 221 students were surveyed along with 80 teachers at public elementary schools on Jeju Island. With the opinions from both parties collected, we have decided to include the teaching performances. There are two parts of an evaluation procedure; an interview section and a storybook section. In the interview section we assessed students' English proficiency by using Solom scales including comprehension, fluency, vocabulary, grammar and pronunciation. In the storybook section we evaluated teaching skills by using such three categories as lesson planning, practice and techniques, and teacher's language use. To increase the validity and reliability inter-rater and intra-rater differences were controlled. But the focus of the program is on the after-the-test measures in encouraging the low-group students to achieve the minimum target levels before their graduation. Extra courses such as English clinic courses and conversation courses were provided during the following vacation periods so that they can improve their teaching skills and English proficiency to the target levels, while some advantageous opportunities provided for the excellent group.	언어학	null	http://dx.doi.org/	kci_detailed_000246.xml
ART001724764	oai_dc	전화 영어 수업 분석과 영어 말하기 능력 증진 효과에 대한 연구	A study on the phone English and its effect on promoting English speaking fluency.	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "정숙경(대전대학교)" ]	The purpose of the study was to measure the effect of phone English conversation through smart phones by investigate the process of three month phone English class. 14 college university students participated in the research. Students learning styles and attitudes towards the phone English were explored. According to main research results. students predominantly preferred phone English class over face-to-face English class due to its availability regardless of time and space, one to one teaching style, and the amount of teachers’ corrective feedback. The t-test result of pre and post online speaking test revealed that phone English class has contributed to improving the students' speaking ability. In spite of students' predominant use of smart phones for phone English, most students are not used to utilizing the internet functions of smart phones for learning purpose.	언어학	null		kci_detailed_000246.xml
ART001724840	oai_dc	「축제」の日本語訳に関する研究－通訳翻訳大学院における使い分け指導を中心に－	A study of translation from Korean word "festival" into Japanese	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "坂野慎治(제주대학교)" ]	The purpose of this paper is to study the usage of Japanese vocabulary which is similar to "festival". ① When it expresses a festival, "Matsuri(祭り)" is generally suitable. "Shukusai(祝祭)" and "Saiten(祭典)" is appropriate when it is unrelated to religion. "Sairei(祭礼)" is appropriate when it relates to religion. ② "Saiten(祭典)" is appropriate for abstract expression. "Shukusai(祝祭)" is used when it includes congratulations. ③ "Shukusai(祝祭)" and "Matsuri(祭り)" is used, when it modifies a noun with an abstract meaning. ④ In the case of religious rituals, "Saishi(祭祀)" is used.	언어학	null		kci_detailed_000246.xml
ART001724791	oai_dc	Bilingual Education, Jim Cummins and the Possibility for Change	Bilingual Education, Jim Cummins and the Possibility for Change	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "아투르 로드리게스(Boise State University)" ]	In this essay I provide a brief review analysis and critique of Bilingual Education in the US and the related theories of Professor James Cummins with analyses of his work, including commentary related to possibilities for change in Bilingual Education practice and theory. I begin with a short vignette, personal experience learning to speak English in the United States. The vignette situates readers in language instruction and socio/cultural-political issues that affect children in US public schools, it provides a basis for a personal analysis of James Cummins’ theories related to bilingual education, BICS and CALP constructs, and critiques posed by Edelsky et al (1983), Martin Jones and Romaine (1986) and MacSwan (2000). Further, I discuss the critiques of Cummins’ work and my understanding of their relationship to bilingual education theory and bilingual students’ language and literacy experiences; the sociocultural, psycholinguistic and political influences of language and literacy acquisition in US public schools.	언어학	null		kci_detailed_000246.xml
ART001724680	oai_dc	수사구조이론에 기초한 영한번역 연구	A Study on English to Korean Translation Based on Rhetorical Structure Theory	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김성옥(대구외국어대학교)" ]	The purpose of this paper is to show that translating involves conveying not only vocabularies or thematic progression in the source text but its hierarchical structure connected through implicit relations termed relational propositions. Based on Rhetorical Structure Theory (henceforth RST), which addresses text organization by means of relational propositions, and explains coherence by a hierarchical structure of texts, this paper analyzes and compares the rhetorical structures of both English texts and their Korean translations in order to discuss incoherence in the target texts.	언어학	null		kci_detailed_000246.xml
ART001724755	oai_dc	원어민 교양영어 수업에 대한 대학생들의 인식 조사	A study of university students' awareness of practical English teaching by native English instructors	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이현구(나사렛대학교)" ]	The purpose of this study is to examine university students' awareness of practical English teaching by native English instructors and to propound an appropriate method to develop a necessary qualification for native English instructors for effective English teaching. A total of 159 university students participated in this study and a questionnaire with 19 items was administered to the students. The questionnaire consists of the English learning environments for learners, the needs for practical English education, and the awareness of practical English teaching by native English instructors. The findings are as follows; 1) the purpose of students' learning practical English is to get a good job 2) English speaking and grammar are regarded as most difficult skills to acquire 3) the native English instructors' ability to speak students' native language is highly demanded. Based on the findings, some pedagogical suggestions are made for improvement on an efficient practical English teaching at university level.	언어학	null		kci_detailed_000246.xml
ART001724737	oai_dc	영작문활동과 교사의 Feedback에 관한 연구	A Study of Teacher Feedback Types on English Writing among Korean Students.	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김우영(한세대학교)" ]	The purpose of this study is to recognize the necessity of English writing with the development of information communication, and to search for the effective feedback for English writing instruction. This study was implemented with 82 high school students and those students were redistributed into four groups: control group given no feedback, form-based feedback group, meaning-based feedback group, and integrative feedback group. Each group were assigned with a different writing homework every week for 5 weeks. Each group was provided with a different type of writing feedback. At the end of the period, each group's first and last submitted writing compositions were evaluated with analytic assessment method, and the improved scores were statistically analyzed by ANCOVA. The results show that there was a significant difference mostly in meaning-based feedback group, in which the lower level students showed the most noticeable improvement and the high level students drew a small score increase. This study proposes that teachers should instruct English writing by using meaning-focused feedback to help students perform communicative conveys. Also, teachers should use a purposeful feedback with the consideration of the students' level.	언어학	null		kci_detailed_000246.xml
ART001724798	oai_dc	An Effective Peer Grouping in Second Language Learning Drawn on Vygotskian Perspective of Peer Interaction	An Effective Peer Grouping in Second Language Learning Drawn on Vygotskian Perspective of Peer Interaction	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "홍영숙(중원대학교)" ]	This paper examines the effects of peer interaction on children’s development, specifically on second language learning in elementary school settings through a literature review. There is a problem to hinder peer interaction in choosing partner, caused by language ability and socio- economic differences. This paper proposes a solution for the problem of active peer interaction during EFL (English as a Foreign Language) classes by investigating the effective ways of group making. I draw on the Vygotskian concept of peer interaction stated as ‘collaboration with more capable peers’ for providing some implications in making groups in the classroom examining several study results. I suggest that teachers should pay more attention to the affective factors such as motivation, emotion, and involvement when they make up peer grouping for activating peer interaction on children’s language learning. I look to Vygotsky not only for the theoretical framework through which to examine these affective factors, but also as a model for teachers who instill confidence in their students by offering caring support.	언어학	null		kci_detailed_000246.xml
ART001724829	oai_dc	韓国語母語話者の「断り」表現の調査研究 -20代と30代を対象として-	A research on the refusal expressions by a Korean native speaker –intended for the twenties and thirties-	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "青木咲野加(경일대학교)" ]	This paper analyzes characteristics of the refusal expressions by a Korean native speaker in their sentence structures. The analysis focuses on the differences between the twenties and thirties or the 「UCHISOTO」. As a result, the following three characteristics are obtained. First, the sentence structure is characterized by the 「C:apology」 + 「D:excuse/reason」for the twenties and thirties, irrespective of the 「UCHISOTO」s. Secondly, the differences between the twenties and thirties are the number of semantic formulas. The thirties use the larger number or the longer length of semantic formulas than the twenties. Thirdly, the 「UCHI」 tend to frequently use the「A:direct refusal」, while 「C:apology」and 「D:excuse/reason」are substantially used by the 「SOTO」.	언어학	null		kci_detailed_000246.xml
ART001724811	oai_dc	Thinking About Literacy in a Time of Transition	Thinking About Literacy in a Time of Transition	{ "journal_name": "한국언어연구학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "스텐 스테이너(boise state university)" ]	Literacy has been defined as reading, writing, listening, speaking, and viewing. Each area is complex in their own way, but surely reading is central to all subject disciplines. As we have come to understand learning to read and write, we know that both are complex and involve a developmental process for learners. While reading and writing share a symbiotic relationship so does listening and speaking. Viewing too has expanded beyond television media into the ever present state of advancing technology. In order for students to do well in their literacy development, adults have to understand the tremendous influence they have on the lives of children through role modeling, providing access to print, exploring the environment, and creating hands on experiences. Adults are also key to providing opportunities for children to interact, learn from each other, and share their understanding with adults. Encouraging questions through inquiry learning, and expression through multiple mediums, are necessary for literacy development among youth. In this manuscript, readers will find thoughts and ideas of how this all makes sense in a time of change.	언어학	null		kci_detailed_000246.xml
ART001966891	oai_dc	소아의 일측 음낭수종 교정술 후 반대측 발생의 치험 1례	A Case Study of Contralateral Occurrence after Unilateral Repair of Hydrocele in Children	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김은진(동국대학교 한의과대학 소아과학교실); 민상연(동국대학교); 김장현(동국대학교)" ]	ObjectivesHydrocele is a common disease found in pediatrics and is usually treated by hydrocelectomy, and even after theunilateral repair of hydrocele, it has been reported that the contralateral hydrocele still occurs in 5.4-12.5%. Therefore, the purpose of this study is to conduct a case study of contralateral hydrocele treated by Oryeong-sanand Bangkeehwangkee-tang (五苓散合防己黃芪湯). MethodsA patient diagnosed with San Syndrome (Su-San) (水疝) was administered Oryeong-san and Bangkeehwangkeetang(五苓散合防己黃芪湯). ResultsThe sizes of hydrocele and symptoms were reduced. ConclusionsIn the case of contralateral occurrence after unilateral repair of hydrocele in children, it is better to select a safertreatment than operation considering other possible complications. In this report, we have proven that Oryeong-sanand Bangkeehwangkee-tang (五苓散合防己黃芪湯) can be very effective in reducing the size of hydrocele,improving symptoms and preventing recurrence.	한의학	null		kci_detailed_000246.xml
ART001966893	oai_dc	소아의 기능성 위장관 질환과 기질 및 성격과의 관계	The Relationship Between Children's Temperament and Character to Functional Gastrointestinal Disorders	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이은주(경희대학교 한의과대학 한방소아과); 김형중(경희대학교 한의과대학 한방소아과); 이선행(강동경희대학교병원); 장규태(경희대학교)" ]	ObjectivesThe purpose of this study is to establish relationship between functional gastrointestinal disorders in children andTemperament and Character using objective criteria and questionnaires. MethodsThis study surveyed 3-6 years old 130 children who were attending the kindergarten or daycare center in thevicinity of Gangdong from May 15th, 2014 to November 30th, 2014. The Korean-translated Questionnaire onPediatric Gastrointestinal Symptoms-Rome III (QPGS-Rome III) and The Junior Temperament and CharacterInventory 3-6 (JTCI 3-6) questionnaires were used. Results1. Between the groups, functional gastrointestinal disorder group scored significantly higher on NS, NS1, NS4,HA4, ST and ST1. 2. As the number of functional gastrointestinal disorders increase, the group scored higher on NS, NS1, NS4,HA4, ST and ST1. ConclusionsThis study showed functional gastrointestinal disorder group exhibited higher NS, NS1, NS4, HA4, ST and ST1scores.	한의학	null		kci_detailed_000246.xml
ART001966888	oai_dc	大柴胡湯이 3T3-L1 지방전구세포와 고지방식이 유도 비만쥐에 미치는 영향	The Effects of Dai-saiko-to (Da-Chai-Hu-Tang) on 3T3-L1 Preadipocytes and High-Fat Diet-Induced Obese Mice	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "민들레(원광대학교 한방소아과); 박은정(원광대학교)" ]	ObjectivesThis experimental study was designed to investigate the effects of Dai-saiko-to (DSH) on differentiation of3T3-L1 preadipocytes and body weight, serum lipid levels in high-fat diet-induced obese mice. Materials and MethodsCells were incubated with DSH at an indicated concentration (0.01-1 ㎎/㎖) for 24h, then the growth rate wasassessed by MTS assay. 3T3-L1 preadipocytes were incubated in DMEM for 2 days with the indicated concentrationsof DSH. On Day 6, the cells were fixed and the cellular lipid contents were assessed by Oil-Red-O staining. Theexpression of peroxisome proliferator-activated receptor γ (PPARγ) and cytidine-cytidine-adenosine-adenosine-thymine(CCAAT)/enhancer-binding proteins α (C/EBPα) as adipocyte-specific proteins were determined by real time RTPCRand western blotting. Four-weeks old mice (wild-type C57BL/6) were used for all experiments. Body weightgain and serum lipid levels were measured in the obesity-induced mice. ResultsDSH did not show toxicity even at the concentration of 1 ㎎/㎖ and DSH significantly inhibited thedifferentiation of 3T3-L1 preadipocytes in a dose-dependent manner. Also, DSH significantly reduced the expressionsof PPARγ and C/EBPα in a dose-dependent manner. Furthermore, DSH significantly reduced body weight gain,serum glucose, total cholesterol and LDL-cholesterol contents in obesity-induced mice. ConclusionsThese results demonstrated that DSH inhibited 3T3-L1 preadipocyte differentiations and high-fat diet-inducedobesity in mice.	한의학	null		kci_detailed_000246.xml
ART001966892	oai_dc	藿香正氣散合六味地黃湯加味方을 처방한 자폐스펙트럼장애 환아 7례	Report on Seven Cases on Patients with Autism Spectrum Disorder Treated by Kwakhyangjungkisanhapyukmijihwangtang-gamibang	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이지나(경희대학교 한의과대학 소아과학교실); 김덕곤(경희대학교); 이진용(경희대학교)" ]	ObjectivesThe purpose of this study is to report seven cases of autism spectrum disorder treated by oriental medicine. MethodsSeven patients who are diagnosed with autism spectrum disorder were treated with herbal medicine(Kwakhyangjungkisanhapyukmijihwangtang-gamibang), and the effect was measured. ResultsAfter the treatment, cognitive skill, speech, motor function, communication skill, and the patients’ generalconditions have gotten better. ConclusionsThis study has shown that the oriental medical treatment for autism spectrum disorder was effective, but furtherstudies are needed.	한의학	null		kci_detailed_000246.xml
ART001966889	oai_dc	소아간질에 관한 문헌고찰- 최근 중의학 저널을 중심으로 -	A Literature Study about Childhood Epilepsy - Focused on Chinese Medical Journals -	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "강경하(원광대학교 한방소아과); 박은정(원광대학교)" ]	ObjectivesThe goal of this study is to investigate childhood epilepsy based on the recent literature of Eastern and Westernmedicine and look for better treatment. MethodsThis study reviewed definition, etiology and therapy method of childhood epilepsy based on 24 studies about thetreatment of epilepsy in childrenResults and ConclusionsBased on the comparison studies, not only herbal medication has shown better efficacy than anti-epileptics, butalso as a monotherapy, or as combination therapies, herbal medications were superior in childhood epilepsy.	한의학	null		kci_detailed_000246.xml
ART001967597	oai_dc	DNCB로 유발된 생쥐의 아토피 피부염에 대한 지실 (枳實)의 효능	Effects of Aurantii Immaturus Fructus (AI) on Atopic Dermatitis (AD) Induced by DNCB in Mice	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "박젬마(동신대학교 한의과대학 소아과학교실); 채중원(동신대학교)" ]	ObjectivesThe purpose of this study was to investigate the effects of AI on AD induced by DNCB in mice. AI hasantiallergic property that is useful in treating allergy-related-diseases, such as asthma, anaphylactic shock, acutebronchitis and skin diseases, skin pruritus from gastrointestinal diseases. However, AI has not been studiedintensively yet regarding anti-inflammatory effect on AD. Therefore, this study was conducted on 2,4-dinitrochlorobezene(DNCB)-induced mice to investigate effects of AI in AD. MethodsIn the experiment, we divided mice into four groups: a normal group (NOR), a control group (CON), an AIspread group (AI spread), and an AI spread and feeding group (AI spread & feeding). Then examined the changesin the body weight, weights of spleen and ear, thickness of dorsum skin and ear skin, clinical aspects on dorsumskin, historical assessments, proliferation of splenocytes in vitro and in vivo, and cytokine (TNF-α, IL-10). ResultsFrom the experiment, the ear weight of AI spread & feeding group was significantly dropped and the earthickness of both AI spread and AI spread & feeding were decreased significantly. Dorsum skin thickness was alsodecreased significantly in both AI spread and AI spread & feeding group. Also, AI treatment improved thesymptoms of AD, such as coloration, erythema and desquamation and had a better effect on AI spread & feedinggroup. In histopathological observation, thickened epidermis, hyperkeratosis, pigmentation, hypergranulosis,parakeratosis were diminished as well in both AI spread and AI spread & feeding group. In vitro, we could observewhen AI was increased as proliferation rate of splenocytes were increased, too. ConclusionsIn conclusion, these data suggest that AI can decrease symptoms of AD and show AI can be useful herbal therapyfor AD.	한의학	null		kci_detailed_000246.xml
ART002086968	oai_dc	한방소아·청소년과 외래 환자 주소증의 최근 경향에 대한 연구	A Study on the Recent Trend of Chief Complaint of Korean Pediatric and Adolescent Outpatients	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이은주(경희대학교 한의과대학 한방소아과); 이보람(경희대학교 대학원 한방소아과); 이지홍(경희대학교 대학원 한방소아과); 장규태(경희대학교)" ]	Objectives The purpose of this study is to investigate about chief complaints of Korean pediatrics and adolescent outpatients in the ○○ university hospital for their recent trend. Methods The study was composed of 4,677 new patients aged between 1 month and 20 years who had been visited pediatrics in ○○ university hospital from 2012 January to 2015 December. Results 1. Among those patients, majority was early childhood as 51.4%, followed by early childhood, late childhood, infancy, and adolescence. 2. Chief complaints in this population have been recorded in the fall the most as 29.6%, but the distribution was inconsistent. 3. To categorize, digestive-related chief complaints were the highest as 30.6%, followed by respiratory, supplemental use, growth, psychiatrics. Respiratory-related chief complaints increased dramatically in the fall. 4. In infancy and early childhood, digestive/respiratory complaints were common, whereas, growth complaints were common in late childhood and adolescence. 5. Digestive/respiratory complaints have been over 50% out of all chief complaints annually. Psychiatric and growth-related complaints have been trending up, whereas, supplemental/skin complaints have decreased every year. 6. Specifically, anorexia were the most common in digestive complaints, and rhinitis/sinusitis were top among respiratory complaints. Precocious puberty and developmental disability increased every year. Conclusions The most common chief complaints were digestive and respiratory-related, and precocious puberty and growth issues have been trending up lately. Based on this result, more studies that targets precocious puberty and growth problems are needed.	한의학	null		kci_detailed_000246.xml
ART002086966	oai_dc	비염을 동반한 틱장애 환아 치험례 보고	A Clinical Study of a Child with Tic-disorder with Allergic Rhinitis Lee Seung Yeon․Yu Sun Ae	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이승연(동의대학교); 유선애(동의대학교)" ]	Objectives The purpose of this study is to report a Tic-disorder child with allergic rhinitis. Methods The child was suffered from Tic-disorder and the allergic rhinitis, and there were two symptoms of all can last more than a year. sometimes the sniffling, as a sin of allergic rhinitis had caused tic disorder. I thought It was needed to control of both of the symptoms at the same time, so I applied the herbal medicine, CheongKanSoYoSan, for Tic-disorder, and carried out the Aromatherapy and the Laser acupuncture for allergic rhinitis. Results After this treatments, the symptoms of Tic-disorder were disappeared according to improving the symptoms of allergic rhinitis. Conclusions It was suggested that we tried to take care of the patient with Tic-disorder, had to considered the other symptoms that were capable of causing.	한의학	null		kci_detailed_000246.xml
ART002086961	oai_dc	한방병원에 내원한 부비동염 환아의 연령 분석 및 임상 유형 분류	A Study on Sinusitis in Pediatric Patients : the Analysis of Age and the Classification of Korean Medical Clinical Type	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이선정(원광대학교 한의과대학 소아과학교실); 강경하(원광대학교 한방소아과); 박은정(원광대학교)" ]	Objectives The purpose of this study is to analyze sinusitis patients who visited the department of pediatrics, OO Korean medicine hospital by using their age and to classify the clinical type by Korean medical theory. Methods The study was conducted based on 178 cases that consisted of sinusitis patients (from 1 to 15 years old) who visited OO Korean medicine hospital from March 2014 to March 2015. We analyzed the age of patients and classified them by the clinical type by reviewing patient's charts. After that, we compared the results with the results of previous studies. Results and Conclusions 178 Patients were studied. 2-years-age group was 19.7% of the study group which was higher than that of previous studies. The Lung-Kidney Yin Deficiency (肺腎陰虛) group was 33.1%, Wind-Heat (風熱) group was 29.8% and the Wind-Cold (風寒) group 18.5%, Spleen-Lung Qi Deficiency (脾肺氣虛) group was 15.7% and the Heart-Spleen Qi Deficiency (心脾氣虛) group was 2.8% of the study group. Children are full of Yang but lack of Yin (陽常有餘陰常不足) so they easily transform into heat and fire (化熱化火). The patients who had sinusitis were most likely to suffer from the common cold for more than a week, once a month. 45.1% of the people from the study group was suffered from common cold more than a week, and 43.8% of the people got common cold once a months. About 21.6 % and 18.3% of the people got common cold twice a month and once every 2 months, respectively. The remaining 15.7% got cold during the season changes.	한의학	null		kci_detailed_000246.xml
ART002086962	oai_dc	두드러기의 침치료에 대한 최근 임상 연구 동향	Recent Clinical Research on Effect of Acupuncture for Urticaria	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "한예지(경희대학교 한의과대학); 이선행(경희대학교 한의과대학); 이진용(경희의료원 한방병원)" ]	Objectives The purpose of this study is to investigate recent clinical studies on the effect of acupuncture for urticaria worldwide. Methods Based on the PubMed search with the key search terms of 'urticaria, acupuncture', dated between 2002 to 2015, a total of 9 randomized controlled trials (RCTs), 3 case series, and 2 case reports have been found, and were analyzed. Results and conclusions 1. The most commonly used acupoints were Quchi (LI 11), Xuehai (SP 10), Zusanli (ST 36), Sanyinjiao (SP 6), Dazhui (GV 14). 2. The most commonly used meridians were The Ren Channel, The Du Channel and The Gall Bladder Meridian of Foot-Shaoyang. 3. The treatment period varied from 12 days to 3 months. 4. Acupuncture treatment found to be significantly more or equally effective than the western medicine. 5. More clinical studies are needed to prove a true effectiveness of the acupuncture for urticaria. In case of laboratory tests, serum immunoglobulin E (IgE), interleukin 4 (IL-4) and Helicobacter pylori negative rate might be helpful.	한의학	null		kci_detailed_000246.xml
ART002086960	oai_dc	수면-각성이행에 초점을 둔 소아 야뇨증 치험 2례	A Case Study of Nocturnal Enuresis in Two Children by Focusing Sleep-wake Transition	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "전보람(동국대학교 한의학과 소아과학교실); 민상연(동국대학교); 김장현(동국대학교)" ]	Objectives The purpose of this study is to report the case of nocturnal enuresis in two children treated by using hypothesis that awareness during sleep may improves symptoms. Methods Enuresis children usually are not even aware of nocturnal urea due to excessive sleep. During the sleep cycle, enuresis children do not tend to have sleep-wake transition period compared to normal children. Ephedrine, the main ingredient of Ephedra sinica (麻黃), has a wakening effect. Two pediatric patients, who were suffering from nocturnal enuresis, were administered by Tosatang-gamibang (菟絲湯加味方) added Ephedra sinica (麻黃) or Boatang-gamibang (補兒湯加味方) added Ephedra sinica (麻黃) while correcting unhealthy voiding habit. Results As a result of the treatment, two pediatric patients were recovered without relapse. Conclusions In this report, we have proven that Tosatang-gamibang (菟絲湯加味方) added Ephedra sinica (麻黃) or Boatang-gamibang (補兒湯加味方) added Ephedra sinica (麻黃) and correcting voiding habit can considerably be effective in recovering nocturnal enuresis.	한의학	null		kci_detailed_000246.xml
ART002086964	oai_dc	알레르기성 비염의 변증과 평가방법에 대한 고찰	Research of Pattern Identification and Outcome Measurement in Allergic Rhinitis	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김지은(대구한의대학교 한의과대학); 백정한(대구한의대학교)" ]	Objectives To evaluate the effectiveness of allergic rhinitis treatment, and to set the ground in clinical studies, adequate outcome measures must be established. Thus, this study was designed to develop useful criteria based on those that have been suggested, and those that we are using today. Methods To assess outcome measures used in allergic rhinitis in Korean medicine, related articles found in Korea Traditional Knowledge Portal from 2000–2015 were evaluated. Then pattern identification and outcome measures were reviewed in each study. Results Among 27 studies, we have found 24 studies used subjective symptoms as outcome measures, 9 studies used quality of life, and most of allergic rhinitis were caused by Spleen-Gi deficiency. Conclusions It is necessary to develop outcome measures that directly reflect pattern identifications in Korean medicine, and those measures need to be further evaluated for their applicability, validity and sensitivity.	한의학	null		kci_detailed_000246.xml
ART002141263	oai_dc	連翹 n-BuOH 분획물의 아토피 피부염 억제 효과	The Effects of Forsythiae Fructus n-BuOH Fraction on Atopic Dermatitis	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이진화(대전대학교 한의과대학 소아과학교실); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]	Objectives Previous studies have found out that Forsythiae Fructus (FF) extracts have anti-atopic activities by in vitro experiment. In order to understand more about FF extracts’ benefit, we subdivided FF extracts depending on systematic fractionation method by using Methylene chloride (MC), Ethyl acetate (EtOAc), n-BuOH and n-hexane (n-Hx). This study is designed to examine the effect of FF fractions on the PMA- ionomycin-induced activation of RBL-2H3 mast cell lines in vitro and on the DNCB-induced activation of NC/Nga mice in vivo. Methods For this study, we examined IL-4, IL-13 production by ELISA analysis, IL-4, IL-13, IL-31, IL-31RA and TNF-α mRNA expression by real-time PCR and manifestations of AP-1 and MAPKs transcription factors by western blotting in vitro. Through in vitro experiment, we selected FF n-BuOH fraction that seems the best effective in atopic dermatitis then induced it on NC/Nga mice by DNCB. We measured mice’s WBC, eosinophil and neutrophil in heart blood, IL-4, IL-5, IFN-γ in the spleenocyte culture supernatant, the absolute cell numbers of CD4+, CD8+, B220+CD23+, CD3+CD69+ and Gr-1+CD11b+ in the PBMCs, ALN and dorsal skin, IL-5, IL-13, IL-31, IL-31RA in the dorsal skin by real-time PCR and the distribution of immune cells by H&E on dorsal skin and ANL and toluidine blue staining on dorsal skin. Results FF n-BuOH fraction suppressed IL-4, IL-13 production and mRNA expression of IL-4, IL-13, IL-31, IL-31RA and TNF-α. Results from the western blot analysis showed that FF n-BuOH fraction reduced the activation of the mast cell specific transduction factors involved in AP-1 by suppressing JNK and ERK phosphorylation. In the gross, atopic dermatitis induced by DNCB in NC/Nga mice were improved by oral administration of FF n-BuOH fraction. Oral FF n-BuOH fraction also decreased the level of IgE in mice’s serum and the level of IL-4 and IL-5 in the spleenocyte culture supernatant, cell numbers of CD8+, B220+CD23+ in the PBMCs, CD4+ in the ALN and CD4+, Gr-1+CD11b+ in the dorsal skin and suppressed mRNA expression of IL-5, IL-13, IL-31, IL-31RA in the dorsal skin. Histological examination showed that infiltration levels of immune cells in atopic dermatitis induced NC/Nga mice were improved by FF n-BuOH fraction. Conclusions FF n-BuOH fraction can reduce pruritus by suppressing IL-31, IL-31RA secretion and modulate molecular mediators and immune cells associated with atopic dermatitis induced in NC/Nga mice which may have played a significant role in recovering atopic dermatitis symptoms.	한의학	null		kci_detailed_000246.xml
ART002141268	oai_dc	Helicobacter pylori 감염과 관련된 철결핍성 빈혈 환아 증례보고	A Case Report of Helicobacter Pylori-Related Iron Deficiency Anemia in a Child; Review of Western Literature	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "전보람(동국대학교 한의학과 소아과학교실); 민상연(동국대학교); 김장현(동국대학교)" ]	Objectives The purpose of this study is to report a case of iron deficiency anemia in a child with repetitive bleeding in the upper gastrointestinal tract caused by Helicobacter pylori infection, and summarize review of a western literature. Methods A 13-year-old patient, who were suffering from iron deficiency anemia from repetitive bleeding in the upper gastrointestinal tract, was administered by Ikwiseungyang-tang gamibang (益胃升陽湯加味方) and Samchulgeonbitang (蔘出健脾湯). After several tests, we realized that an iron deficiency anemia was related to Helicobacter pylori. Results By herb medication, the patient's symptoms were alleviated. Conclusions Helicobacter pylori infection is one of the reasons of refractory iron-deficiency anemia which is unresponsiveness to oral iron therapy. We report the findings of herb medication along with summarization of a western literature.	한의학	null		kci_detailed_000246.xml
ART002141277	oai_dc	식간 (食癎)으로 진단된 영아기 환아 1례에 대한 증례 보고	A Case Report of Infant Diagnosed as Sik-Gan (食癎)	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이은주(경희대학교 한의과대학 한방소아과); 이보람(경희대학교 대학원 한방소아과); 이지홍(경희대학교 대학원 한방소아과); 장규태(경희대학교)" ]	Objectives The purpose of this study is to report a case of one infant patient diagnosed as Sik-Gan (食癎) who was treated by Korean medical treatment. Methods We diagnosed an infant patient as Sik-Gan (食癎) and treated him with herbal medicine, acupuncture, moxa and chuna therapy while correcting his eating habit. To measure the degree of the patient’s progress, the frequency and exact symptoms of seizure events, and gastrointestinal symptoms were recorded. Results Korean medical treatment reduced the patient's the frequency of seizure, and improved gastrointestinal symptoms. Conclusions A patient who has past medical history of epileptic seizures, unhealthy eating habits and gastrointestinal malfunctions is prone to have a specific form of seizure called the Sik-Gan (食癎). In this report, we have proven that variety of Korean medical treatment can considerably be effective in preventing recurring seizure events and improving the patients’ gastrointestinal symptoms.	한의학	null		kci_detailed_000246.xml
ART002141265	oai_dc	알레르기성 비염환아들의 양도락 특성에 관한 연구	The Study on the Characteristics of Ryodoraku Score in the Children with Allergic Rhinitis	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "안주현(경희대학교 임상한의학과 소아과학교실); 이진용(경희대학교)" ]	Objectives The purpose of this study is to investigate the characteristics of Ryodoraku Score in the children who visited department of pediatrics, hospital of Korean medicine with allergic rhinitis as the chief complaint. Methods Subjects were 80 children with allergic rhinitis. We calculated the average Ryodoraku Score (RS, μA), and compared the average of each meridian system. And we classified the children by several groups (depending on age, additional allergic disease), and accomplished a comparative analysis. Results 1. The average of Ryodoraku Score in 80 children was 76.36 ± 22.72. 2. The figure of H3 (心), H5 (三焦), F1 (脾), F2 (肝), F3 (腎), F4 (膀胱), F5 (三焦), F6 (胃) had significant statistical differences compared to the total average. 3. Comparing the group having only allergic rhinitis to group having allergic rhinitis and other allergic disease, showed significant statistical difference in H2 (心包), H3 (心). 4. Analyzed by age, there's a significant statistical difference in F1 (脾), F4 (膀胱). Conclusion We found that H5 (三焦), F1 (脾), F4 (膀胱) showed significant statistical difference in Ryodoraku Score, and F1 (脾) had the highest relevance. The research indicate meaningful difference depending on age, additional allergic disease.	한의학	null		kci_detailed_000246.xml
ART002141280	oai_dc	관동화 및 관동화 가미방이 흰쥐의 간독성 및 신독성에 미치는 영향	Studies on Hepatic and Renal Toxicities Possibly Induced by Administration of Farfarae Flos in Rats	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김은진(동국대학교 한의과대학 소아과학교실); 민상연(동국대학교); 김장현(동국대학교 분당한방병원)" ]	Objectives This study is to investigate whether oral administration of Farfarae flos, JCT (Jeong-cheon-tang), CPT (Cheong-pye-tang) and CPK (Cheong-pye-tang- ga-kwandonghwa) will affect both the levels of serum GOT, GPT, blood urea nitrogen (BUN) and creatinine in SD rats or not, and will change body weight of the rats. Materials and Methods 18 SD rats were randomly divided into 6 groups . including a control group (vehicle 2 ml/rat), Farfarae flos water extract (extract 2 ml/rat), Farfarae flos fine powder (emulsion 2 ml/rat), JCT (extract 2 ml/rat), CPT (extract 2 ml/rat) and CPK (extract 2 ml/rat) group. The drugs were administered to rats for 2 weeks or 30 days (for control and Farfarae flos fine powder group only) and serum GOT/GPT activities and BUN/creatinine concentrations were measured. Also, the changes of body weights of each rat was measured. Results (1) Farfarae flos water extract, Farfarae flos fine powder emulsion, JCT and CPT and CPK did not cause any changes in serum GOT/GPT activities and BUN/creatinine concentrations compared to the ones in control group. (2) There are no significant changes in rats’ body weight among the experimental groups during the experimental period. Conclusions Contrary to the reports on human data, 2 weeks or 30 days of oral administrations of Farfarae flos itself and decoctions containing Farfarae flos did not provoke hepatotoxicity and nephrotoxicity.	한의학	null		kci_detailed_000246.xml
ART002141326	oai_dc	열성 경련에 대한 중의학 임상 연구 동향 - RCT를 중심으로 -	Review of Clinical Research on Effect of Traditional Chinese Medicine for Febrile Seizure	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이보람(경희대학교 대학원 한방소아과); 이은주(경희대학교 한의과대학 한방소아과); 이지홍(경희대학교 대학원 한방소아과); 장규태(경희대학교)" ]	Objectives The purpose of this study is to provide clinical evidence of Korean medicine for febrile seizure by review of randomized controlled trials on the effect of TCM (traditional Chinese medicine) for febrile seizure. Methods We searched randomized controlled trials about TCM treatment of febrile seizure from the China National Knowledge Infrastructure (CNKI) (January 2008 to June 2016). The selected literatures were assessed by Jadad scale. Results 40 papers were selected from 160 studies. Analyses of selected studies indicated that the TCM treatment group has significantly higher cure rate for febrile seizure than first aid or western medicine group. The most commonly used herbs were Gardeniae Fructus (梔子), Uncariae Ramulus cum Uncis (鉤藤), Cornus Gazeliae (羚羊角), Margarita (珍珠), Scutellariae Radix (黄芩), Glycyrrhizae Radix (甘草). The most commonly used acupoints were GV26 (人中), LI4 (合谷), KI1 (湧泉), GV20 (百會). There were no serious adverse events reported from the TCM treatment group during the treatment period. Conclusions TCM has been shown as not only effective but also safe treatment on febrile seizure. This finding can be widely utilized in clinical practice and can form the basis for development of clinical practice guidelines in future.	한의학	null		kci_detailed_000246.xml
ART002141328	oai_dc	소아 식욕부진의 외치법에 대한 연구 동향 - 최근 중의잡지를 중심으로 -	Recent Clinical Research on the Effect of External Therapy for Infantile Anorexia - Based on the Recent Traditional Chinese Medical Journal -	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이지영(동의대학교 한의과대학 소아과학교실); 이승연(동의대학교); 유선애(동의대학교)" ]	Objectives The purpose of this study is to investigate recent clinical studies on the effect of external therapy for infantile anorexia. Methods We searched for the study at CNKI by a keyword ‘xiaoaryanshizheng’ after 2010. 40 clinical studies which were using one external therapy method were selected. Result Selected 40 clinical studies were divided into six types of external therapy. The subjects for these clinical studies were between three months and 14 years old children. The number of the subjects was between 20 and 260. The period of treatment was between three days and three months. Only using one external therapy for infantile anorexia had 84.62%-100% cure rate. Conclusions Based on these clinical studies, external therapy has been shown as an effective treatment on infantile anorexia.	한의학	null		kci_detailed_000246.xml
ART002141272	oai_dc	국소한약외용제의 알레르기성 비염 치료 효과에 대한 문헌 고찰	A Literature Study of Topical Application of Chinese Herbal Medicine for Allergic Rhinitis	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "방미란(동국대학교 한의과대학 소아과교실); 김장현(동국대학교); 민상연(동국대학교)" ]	Objectives The purpose of this study is to analyze studies about the effects of topical application of Chinese herbal medicine for allergic rhinitis within randomized controlled trials (RCT). Methods The search database includes KJTK (Korean Traditional Knowledge Portal), OASIS (Oriental Medicine Advanced Searching Integrated system), CNKI (China National Knowledge Infrastructure), PubMed, and EMBASE. We used the following key search terms: “allergic rhinitis”, “traditional Chinese medicine”, “traditional Korean medicine”, “Chinese herbal medicine”, “randomized controlled trial”, “clinical study”, “nasal spray”, and “nasal drop” Results Five studies were selected for analysis. Three studies used nasal spray of Chinese herbal medicine and two studies used nasal drops of Chinese herbal medicine for the intervention. Frequently used herbs were Magnoliae Flos (辛夷), Scutellariae Radix (黃芩), Coptidis Rhizoma (黃連), and Astragali Radix (黃芪). For the outcome measures, studies used symptom score, questionnaire of Quality of Life, nasal airway resistance, or laboratory studies. From all 5 studies, it has been shown that topical application of Chinese herbal medicine was effective for improving symptoms of allergic rhinitis. Two out of five studies showed statistical difference between study group and control group. Conclusions This study shows that topical application of Chinese herbal medicine can improve symptoms of allergic rhinitis. Well-designed RCT studies with low risk of bias and studies with outcome measures for assessing the immunomodulatory effects are necessary to confirm these findings.	한의학	null		kci_detailed_000246.xml
ART002141338	oai_dc	소아비만의 치료에 대한 국내 임상연구 동향	Review of Korean Clinical Studies on Treatment for Childhood Obesity	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김경리(대전대 한의과대학 소아과학교실); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]	Objectives The purpose of this study is to investigate Korean clinical studies on treatment of childhood obesity and to propose for better treatment options for childhood obesity. Methods Based on RISS, KISS, OASIS, KMbase with the keyword ‘childhood obesity’, ‘child obesity’, ‘obese child’, ‘overweight child’, total of 21 randomized controlled trials (RCTs), 11 single clinical studies, 3 chart reviews and 3 case reports have been found, and were analyzed. Results and Conclusion 1. Some study subjects were classified based on their sex - only men or women in a group or sometimes both. Another way of classify the study subjects were based on their age - preschooler, primary school students, middle school students, and high school students. The diagnostic criteria of the subjects were BMI (body mass index), Body fat percentage, Obesity index, Weight and unknown criteria. 2. The treatments used in 38 studies were exercise alone, education alone, both exercise and education or herbal therapy. The 7 studies that used herbal therapy as part of their study intervention had a study group with herbal intervention only and the other 2 study group with herbal treatment in addition to exercise and education. 3. 9 studies included herb medicines, electroacupuncture, auricular acupuncture, cupping, aroma massage, infrared light, and abdomen pad. Herb medications used in 5 studies included Chegameuiin-tang 2 kinds, Sobieum, Biman-tnag, and I-razin. 4. The methods of assessment used in 38 studies were classified by 7 categories and anthropometry parameters which is the basic methods are used in all studies 5. Almost studies (29 studies in all 38 studies) were using anthropometric parameters results on significantly effectiveness of childhood obesity. 6. More studies are needed to prove true effectives from various treatments, especially herbal therapy for childhood obesity.	한의학	null		kci_detailed_000246.xml
ART002111999	oai_dc	소아 반복성 호흡기 감염의 한약 치료에 대한 임상 연구 동향: 중의학 논문을 중심으로	Review of Clinical Research about Herbal Medicine Treatment on Recurrent Respiratory Tract Infection in Children	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이지홍(경희대학교 대학원 한방소아과); 이은주(경희대학교 한의과대학 한방소아과); 이보람(경희대학교 대학원 한방소아과); 장규태(경희대학교)" ]	Objectives The purpose of this study is to investigate recent clinical studies on effect of herbal medicine treatment for recurrent respiratory tract infection in children. Methods We searched some clinical studies about recurrent respiratory tract infection in children from the China Academic Journal (CAJ) of China National Knowledge Infrastructure (CNKI) (January 2011 to December 2015). Results 50 papers were selected from 168 studies. The herbal decoction was main herbal medicine treatment for recurrent respiratory tract infection in children. Commonly used herbs were Atractylodis Rhizoma Alba, Glycyrrhizae Radix, Astragali Radix, Saposhnikovia Radix and Pseudostellariae Radix. Yupingfeng keli was the most frequently used herbal compound. Total effective rate was 66.4-100%, experimental group was significantly higher than control group in 45 papers (P<0.05). Immune index (in 22 papers) and curative effect of TCM syndrome (in 7 papers) were significantly higher than those of control group after treatment (p<0.05). Conclusions Herbal medicine has been shown as an effective treatment on recurrent respiratory tract infection in children. These research results can be utilized in other clinical studies and in treatment of recurrent respiratory tract infection for children.	한의학	null		kci_detailed_000246.xml
ART002112000	oai_dc	조협 추출물이 HaCaT cells의 항염증과 SEB-1 cells의 피지분비 억제에 미치는 영향	The Effects on Anti-inflammatory Action in HaCaT Cells and Inhibiting Sebum Secretion in SEB-1 Cells by Gleditsiae Fructus Extract	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "구은진(대전대학교 한의과대학 소아과학교실); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]	Objectives The purpose of this study is to investigate the effects of Gleditsiae Fructus 70% EtOH extract (JS_E) on anti-inflammatory action in HaCaT cells (A spontaneously immortalized human keratinocyte cell line) and inhibiting triglyceride genesis in SEB-1 cells (Immortalized human sebocyte). Methods The anti-inflammatory effect of JS_E was analyzed by enzyme-linked immunosorbent assays (ELISA) which measured levels of IP-10, RANTES and MDC in HaCaT cells. Also the effect on secretion of sebum of JS_E was analyzed by TG-S kit which measured the quantity of triglyceride in SEB-1 cells. Results JS_E inhibited IP-10, RANTES and MDC expression in a dose dependent manner. IP-10 expression was inhibited significantly in comparison to TNF-α and IFN-γ recombination (TI) control group at concentration of JS_E 200 ㎍/㎖ and RANTES and MDC expressions were inhibited significantly at concentration of JS_E 100, 200 ㎍/㎖. JS_E also inhibited triglyceride secretion of SEB-1 cells significantly in comparison to the control group in a dose dependent manner. Conclusions This study shows that JS_E has the effects of anti-inflammatory action and inhibiting sebum secretion. According to these results, JS_E can be used for treating skin diseases such as acne and dermatitis caused by inflammation and excessive secretion of sebum by controlling the activity of the HaCaT and SEB-1 cells.	한의학	null		kci_detailed_000246.xml
ART002111979	oai_dc	한방 영유아 건강검진 도입 필요성 연구	Research for Health Examinations for Infants and Children by Korean Medicine	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "유승주(부산대학교 한의학전문대학원); 천진홍(부산대학교); 김기봉(부산대학교)" ]	Objectives This study is to analyze current guidelines for health check-ups in infants and children, and to develop better guidelines based on oriental medicine. Methods We analyzed The Manual of 2015's Health Examination for Infants and Children which is a Korean Developmental Screening Test for Infants and Children (K-DST). The statistics from the test was collected from 2010 to 2014 to figure out the problems of Health Examinations for Infants and Children. 20 articles from 2000 to 2014 from RISS, NDSL were also analyzed. Results The current guidelines for health examinations in infants and children didn't include major pediatric diseases such as allergy and asthma. Also, the pediatrics health education materials were mainly focused on hypernutrition but not so much on nutrition deficiency. The number of the centers for Health Examinations for Infants and Children was 52.2% of the number of NIP-Participating medical institutions for infants and children. Conclusions Oriental medicine can be useful to prevent major pediatric diseases and to promote general health in pediatrics. By legislating 'Geon-a-beop', which is a law for infants and children, we can increase the number of medical centers for infants and children to get health check-ups. Currently, there are 9,769 Korean medical institutions, and the rate of traditional medical doctors of public health doctors was 25.5%. Weak Children Questionnaire is developed, considered to be more useful when it is developed with 5-point scale rather than 2.	한의학	null		kci_detailed_000246.xml
ART002111996	oai_dc	소아청소년의 脾虛證과 체질량 지수 및 식습관과의 관계에 대한 조사 연구	The Study on the Correlation Between Spleen Deficiency Syndrome, Body Mass Index (BMI) and Eating Habit in Children and Adolescents	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김빛나래(동신대학교 한의과대학); 유수향(동신대학교); 이다은(동신대광주한방병원); 채중원(동신대학교)" ]	Objectives The purpose of this study is to understand the correlation between spleen deficiency syndrome, body mass index (BMI) and eating habit in children and adolescents and to provide foundation of preventive care and treatment. Methods A survey was conducted with 115 children and adolescents, who were 4th, 5th and 6th grade of elementary school in Gwangju from March 2nd, 2016 to April 8th, 2016. Body mass index (BMI) was calculated using the measured height and weight. Spleen deficiency syndrome and eating habit in children and adolescents were investigated by using the Deficiency of the Spleen Questionnaire and Korean Children's Eating Behaviour Questionnaire (K-CEBQ). A data analysis was performed by using SPSS 23.0 program. Results 1. There was no statistically significant correlation between spleen deficiency syndrome and body mass index (BMI). 2. Children and adolescents with spleen deficiency syndrome were interested in food rather than avoided it. 3. There was a positive correlation between body mass index (BMI) and FR (Food responsiveness), “Food approach”. The correlation between the healthy weight group and FR is statistically significant negative correlation. Conclusions Due to various limitations, it is difficult to generalize the correlation between spleen deficiency syndrome, body mass index (BMI) and eating habit in children and adolescents. Therefore additional research is necessary to confirm this study’s findings.	한의학	null		kci_detailed_000246.xml
ART002111995	oai_dc	東醫寶鑑小兒門處方에 대한 考察	Study on Treatment Options for Pediatrics Based on DongEuiBoGam	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "민들레(상지대학교)" ]	Objectives The purpose of this study is to find a way to apply current oriental pediatrics treatment guidelines based on a pediatric chapter in DongEuiBoGam. Methods I learned pediatrics prescription formula, indications of drugs, dosage regimen from DongEuiBoGam, and I classified herbs that can be used for pediatrics prescriptions based on their types, effects, tempers, flavors, toxicities, and attributive channels. Results & Conclusions I learned similarities among pediatrics prescription regimens and the herbs commonly used in pediatrics. Also, I found out physiological and pathological characteristics in pediatrics. I expect that this study would be helpful for current oriental pediatric treatments.	한의학	null		kci_detailed_000246.xml
ART002111976	oai_dc	豆豉 추출물을 이용한 下胎毒法이 NC/Nga 생쥐에서 유발된 아토피 유도 피부염에 미치는 항염증 효과	The Anti-inflammatory Effects of Hataedock Taken Douchi Extracts on Atopic Dermatitis-like Skin Lesion of NC/Nga Mouse	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "엄선호(부산대학교); 안상현(부산대학교); 박선영(세명대학교); 천진홍(부산대학교); 김기봉(부산대학교)" ]	Objectives Hataedock is a Korean herbal medical oral treatment that removes fetal toxic heat and meconium from new born babies. The purpose of this study is to evaluate whether Hataedock treatment of Duchi extracts has anti-inflammation effects on AD (Atopic Dermatitis)-induced NC/Nga mice. Methods After Hataedock treatment of Duchi extracts on days 0, 3-week-old NC/Nga mice were sensitized on days 28, 35, 42 by exposure of DNFB (dinitrochlorobenzene) and were induced to have AD. Immunohistochemistry of NF- κB p65, iNOS, COX-2 and TUNEL assay of apoptotic body was used to identify changes of skin damages and anti-inflammation effects. Results The alleviate effect of the skin damage and angiogenesis was observed in DT group. The damage of stratum corneum, hyperplasia, edema, infiltration of lymphocytes and distribution of capillary were decreased in DT group. Also, the study results suggested that Hataedock treatment of Duchi extracts in DT group remarkably downregulated levels of NF- κB p65 by 70% (p < 0.001), as well as COX-2 by 51%, iNOS by 62% (p < 0.001). Additionally, Hataedock treatment of Duchi extracts in DT group up-regulated apoptosis of inflammatory cells by 68% in atopic dermatitis-like skin lesion. Conclusions From the study results, we observed that Hataedock treatment of Duchi extracts alleviates AD through diminishing various inflammatory cytokines in the skin lesions, which are involved in the initial steps of AD development. It is anticipated to have potential applications for prevention and treatment of atopic dermatitis.	한의학	null		kci_detailed_000246.xml
ART002111992	oai_dc	사시의 침치료에 대한 최근 임상 연구 동향	Recent Clinical Research on Effect of Acupuncture for Strabismus	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이지나(경희대학교 한의과대학 소아과학교실); 이선행(경희대학교 한의과대학 임상한의학과 소아과학교실); 이진용(경희대학교)" ]	Objectives The purpose of this study is to investigate recent clinical studies on effect of acupuncture for strabismus in Korea and other countries. We have analyzed 10 years (from 2006 to 2015) of case studies and randomized controlled trials (RCT) on effect of acupuncture for strabismus. Methods The search database includes Oasis, KTKP (Korean Traditional Knowledge Portal), Medline, Embase, and Cochrane library. To narrow the search, the following key search terms were used: 'strabismus, acupuncture'. The search was limited to the publication date from 2006 to 2015. 7 case studies and 5 control studies were selected for analysis. Results and Conclusions 1. The acupuncture treatment is effective for paralytic strabismus 2. The studies used BL1, GB1, ST2, TE23, GB15, EX-HN5, ST1, and LI4 acupoints and also an electroacupuncture treatment, which is 15 minutes of extraocular muscle stimulation, was used. 3. Degree of strasbismus was tested by Ocular motor range test, Corneal light reflex test, Ocular abducent scale test (Scott and Kraft, Diploptic range test).	한의학	null		kci_detailed_000246.xml
ART002111994	oai_dc	인후통의 침치료에 대한 국외 임상 연구 동향	Recent Clinical Research on Effect of Acupuncture on Sore Throat	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "한예지(경희대학교 한의과대학); 이선행(경희대학교 한의과대학 임상한의학과 소아과학교실); 이진용(경희대학교)" ]	Objectives The purpose of this study is to investigate recent clinical studies on the effect of acupuncture on sore throat. Methods Based on the PubMed search with the key search terms of 'sore throat, acupuncture', dated from 1992 to 2015, 7 controlled trials and 8 case series was found, and were analyzed for this study. Results 1. The most commonly used acupoints were Quchi (LI11), and Hegu (LI4). 2. The most commonly used meridians were The Lung Meridian of Hand-Taiyin and The Large Intestine Meridian of Hand-Yangming. 3. Acupuncture treatment was effective for both acute and chronic sore throat. 4. More clinical studies are needed to prove the effectiveness of the acupuncture on sore throat. To be more objective on the study results, we can measure temperature drops on or amount of analgesic consumption for sore throat after acupuncture treatment.	한의학	null		kci_detailed_000246.xml
ART002111993	oai_dc	滋陰降火湯이 호흡기 점액의 생성 및 분비에 미치는 영향	Effect of Jaeumganghwa-tang on Production and Secretion of Respiratory Mucus	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "천진홍(부산대학교); 민상연(동국대학교); 김장현(동국대학교)" ]	Objectives In this study, the effects of Ja-eum-gang-hwa-tang (JGT) on the increase in airway epithelial mucosubstances of rats and ATP- or PMA- or EGF- or TNF-α-induced MUC5AC mucin production and gene expression from human airway epithelial cells were investigated. Materials and Methods Hypersecretion of airway mucus was produced by exposure of SO2 to rats for 3 weeks. The effect of orallyadministered JGT for 2 weeks on increased epithelial mucosubstances from tracheal goblet cells of rats was assessed by using histopathological analysis after staining the epithelial tissue with Hematoxylin-eosin and PAS-alcian blue. Possible cytotoxicity of JGT was assessed by investigating the potential damage on kidneys and liver functions by measuring serum GOT/GPT activities and serum BUN concentration of rats and the body weight gain during experiment. Also, the effect of JGT on ATP- or PMA- or EGF- or TNF-α-induced MUC5AC mucin production and gene expression from human airway epithelial cells (NCI-H292) were investigated. Confluent NCI-H292 cells were pretreated for 30 min in the presence of JGT and treated with ATP (200 μM) or PMA (10 ng/㎖) or EGF (25 ng/㎖) or TNF-α (0.2 nM) for 24 hrs to assess the effect of JGT both on ATP- or PMA- or EGF- or TNF-α-induced MUC5AC mucin production by using enzyme-linked immunosorbent assay (ELISA) and on gene expression by the same inducers using reverse transcription-polymerase chain reaction (RT-PCR). Results (1) JGT decreased the amount of intraepithelial mucosubstances of trachea of rats. (2) JGT did not show any renal and hepatic toxicities, and did not affect body weights either. (3) JGT significantly inhibited ATP-, PMA-, EGF-, and TNF-α-induced MUC5AC mucin productions from NCI-H292 cells. (4) JGT inhibited EGF-, and PMA-induced expression levels of MUC5AC gene in NCI-H292 cells. However, ATP- and TNF-α-induced MUC5AC gene expression levels were not affected in NCI-H292 cells. Conclusions The result from the present study suggests that JGT might control the production and gene expression of airway mucin observed in various respiratory diseases which accompanied by mucus hypersecretion. Also, JGT did not show liver toxicity or impact on kidney functions. The effect of JGT should be further studied by using animal experimental models which can show proper pathophysiology of airway diseases.	한의학	null		kci_detailed_000246.xml
ART002053296	oai_dc	소아 추나에 대한 국내·외 연구 동향	Domestic and Foreign Research Trend on the Pediatric Chuna Treatment	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이진화(대전대학교 한의과대학 소아과학교실); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]	Objectives The purpose of this review is to investigate the domestic and foreign studies of pediatric Chuna treatment and propose the directions of future studies and clinical applications. Methods We searched for the study at RISS, KISS, DBPIA, Pubmed, CNKI by keywords, ‘추나’, ‘Osteopathic’, ‘Chiropractic’, ‘Manipulation’, ‘推拿’, ‘导引’, ‘按摩’, After 2010. Results 1. Selected 3 domestic studies were categorized as 1 survey study and 2 case reports. Selected 41 foreign studies from Pubmed were categorized as 15 systemic reviews, 8 survey studies, 12 case reports and 6 control studies. Selected 82 foreign studies from CNKI were categorized as 10 systemic reviews, 22 case reports and 50 control studies. 2. 2 clinical domestic studies researched on idiopathic Scoliosis. The foreign clinical studies from Pubmed are 18 cases, and those studies were categorized into Premature baby care (3), Infant colic (2), ADHD (2), Congenital talipes equinovarus (1), Somatic dysfuntion (1), Nonsynostotic occipital plagiocephaly (1), Conversion disorder (1), Lower back pain (1), Chronic bilateral dorsal foot pain and stiffness (1), plantar fasciitis (1), Migraine headaches (1), Cyclic vomiting syndrome (1), Acute otitis media (1) and Cerebral palsy (1). The other 72 foreign clinical studies were from CNKI, and they studied 39 different diseases. Systematically, they studied about digestive diseases (25), respiratory diseases (20), fever (6), musculoskeletal diseases (5), nervous system diseases (5), dermatology diseases (2) and other disease states. The Chuna treatment was used in variety of studies. 3. 2 clinical domestic studies adopted techniques of Osteopathy Chuna. The foreign clinical studies from Pubmed adopted techniques of Osteopathic manipulation (10) and Chiropractic manipulation (8). The other foreign clinical studies from CNKI adopted techniques of Acupressure (69), Abdominal manipulation (23), Spinal manipulation (21), Thoracic manipulation (11), Traction manipulation (2), Muscular manipulation (2), Squeezing Sha manipulation (1), Spine correction (1), Joint manipulation (1) and Fascia manipulation (1). Conclusions In addition to musculoskeletal disorders, variety of pediatric diseases could be treated with Chuna treatment instead of acupuncture.	한의학	null		kci_detailed_000246.xml
ART002053297	oai_dc	알레르기성 비염의 한의학 및 보완대체의학적 치료에 대한 국내 임상 연구 동향	Review of Clinical Studies on Korean Medicine and Complementary and Alternative Medicine Treatment for Allergic Rhinitis in the Korean Literature	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "구은진(대전대학교 한의과대학 소아과학교실); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]	Objectives The purpose of this study is to analyze Korean clinical studies in Korean medicine and complementary and alternative medicine for allergic rhinitis and to propose for better methods of clinical studies and effective treatments on allergic rhinitis. Methods Electronic researches were performed with NDSL, RISS, KISTI, KISS, OASIS by keyword ‘Allergic rhinitis'. Results The treatments used in 36 studies were herbal medicines, acupuncture, pharmacopuncture, moxibustion, cupping, inject medicine to nasal cavity, aroma therapy, ointment, nasal cleansing solution, laser treatment, infra-red therapy, oxygen nebulizer, diet treatment, moxa-pellet treatment, mindfulness meditation and space-spine manipulation techniques. The most common acupoints were LI4 and LI20 (Large Intestine Meridian). The most common methods of assessment is subjective nasal symptoms. All studies using subjective nasal symptoms and quality of life as assessment methods to show valid results on the improvement of allergic rhinitis. Conclusions This study shows that Korean medicine and complementary and alternative medicine on allergic rhinitis are effective. It will be expected to use that various methods for allergic rhinitis and more clinical studies for allergic rhinitis and pediatric patients needed in the future.	한의학	null		kci_detailed_000246.xml
ART002053290	oai_dc	소아근시에 대한 눈 주위혈 지압의 유효성 및 안전성 평가 연구	The Efficacy and Safety of Periocular Acupoint Stimulation on Myopia Progression in Children: A Study Protocol	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김기봉(부산대학교 한의학전문대학원 임상의학부, 부산대학교 한방병원 한방소아과); 차호열(부산대학교 한방병원 한방소아과); 정아람(부산대학교 한방소아과); 천진홍(부산대학교 한의학전문대학원 임상의학부, 부산대학교 한방병원 한방소아과); 최준용(부산대학교)" ]	Objectives Myopia has a higher prevalence rate in eastern countries, which also have a higher rate of educational fever compared to western countries. Considering this, social costs paid for myopia will increase rapidly in Korea. Although the development of myopia treatment is necessary, there has been a lack of relevant studies. Thus, this study aims to produce data to prevent unnecessary treatments and medical expenses. Methods The objective is to evaluate the effect of periocular acupressure exerted by a medical massager for myopia. This is an open-label, prospective, single-arm, and pre and post superiority study. The subjects are 7~12-year-old myopia patients with under 5 D (diopter) of spherical equivalent. A total of 56 subjects were enrolled. The selected subjects will wear the massager for 15 minutes twice a day for 24 weeks. The primary endpoint is the refraction change. The secondary endpoint is the axial length change. Statistical analysis was performed at a significant level of 0.05, using a two-tailed test. The criterion for significantly improved refraction was -0.17±0.50 D/6 months and that of axial length change was 0.126 mm. Results and Conclusions This study did not include a control group because children represent a vulnerable group. This objective study will bring some impact on Korean medical myopia treatment. A long-term confirmatory clinical study may be necessary in future.	한의학	null		kci_detailed_000246.xml
ART002053293	oai_dc	성장판의 성장에 저단계 레이저가 미치는 영향에 대한 고찰	Review of Low Level Laser Therapy on The Growth of Epiphyseal Plate	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "최지원(우석대학교 한의과대학 한의학과); 장인수(우석대학교); 정민정(우석대학교)" ]	Objectives We aimed to identify the effectiveness of photobiomodulation using low level laser therapy (LLLT), light emitting diode (LED) and others on the growth of the length of the growth plate by reviewing literatures. Methods We searched literatures using PubMed, Science Direct, CINAHL, Korea Traditional Knowledge Portal (KTKP), Oriental Medicine Advanced Searching Integrated System (OASIS), China Knowledge Resource Integrated Database (CNKI), Japan Science and Technology Information Aggregator, Electronic (J STAGE), and Japan National Institute of Informatics Scholarly and Academic Information Navigator (CiNii) using the keywords “Growth plate” “Epiphyseal growth” “Epiphyseal plate” and “Laser”, “light emitting diode (LED)”, “near-infrared light”, and “photobiomodulation”. Search range included only original article which provided English abstract were selected. The search strategy contained no language limitation. Results A total 556 studies were found. Then, 551 were excluded by scanning titles and abstracts and finally 5 articles were selected. Five articles were RCTs using rodents. Two of the 5 articles used InGaAlP Laser (630-685 nm), and the other 3 articles used GaAlAs Laser (780, 820, and 870 nm) to investigated the effects of LLLT on the growth of the length of the epiphyseal cartilage and the number of chondrocytes and thickness of each zone of the epiphyseal cartilage. Two articles concluded that LLLT had a beneficial effect on the longitudinal growth of the growth plate. In growth of the epiphyseal plate, there were no significant differences in others. Conclusions It is might that LLLT influenced on the growth of epiphyseal plate by positive affect. However, further rigorous RCTs are warranted.	한의학	null		kci_detailed_000246.xml
ART002053298	oai_dc	교통사고 후 夜啼, 夜驚 증상을 보인 소아 환자 35명에 대한 증례보고	The Clinical Study of Night Crying and Night Terror in Children after Traffic Accidents	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "강경하(원광대학교 한방소아과); 이선정(원광대학교 한의과대학 소아과학교실); 박은정(원광대학교)" ]	Objectives The purpose of this study was to report 35 children who had sleep disorder like night crying or night terror after traffic accidents. Methods This clinical study had been carried out with 35 infants and children, who visited to the department of Pediatrics, ○○ Oriental Medical Hospital from January 2012 to June 2015. Results The study group had similar sex the ratio between boys and girls and the group had more of 1-3 year-old children. The number of patients who were diagnosed as night crying were 24, night terror were 7 and palpitation due to alarm were 4. All patients took herb medicine and 15 patients were treated by acupuncture. During the treatment, symptom of night crying and terror were disappeared. Conclusions This result showed that the oriental medical treatment was effective in children who suffered from night crying or night terror after traffic accidents.	한의학	null		kci_detailed_000246.xml
ART002053288	oai_dc	허약아의 수면 습관에 대한 연구	A Study on Sleep Habits of Weak Children Groups	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김민주(경희대학교 한의과대학 한방소아과); 이선행(강동경희대학교병원); 이진용(경희의료원 한방병원)" ]	Objectives The purpose of this study is to research on sleep habits of weak children groups using objective evaluation tools. Methods This study surveyed 108 children and adolescents of 4~10 years old who visited the department of Pediatrics of ○○ Korean Medicine Hospital from June 19th, 2015 to August 28th, 2015. Weak Children Questionnaire and CSHQ (The Children’s Sleep Habits Questionnaire) were used to research on sleep habits of children. We analyzed the data by using PASW Statistics 18.0 with independent t-test. Results CSHQ Score of Weak Children Group was significantly higher than CSHQ Score of Normal Children Group (p<0.05). CSHQ Score (Mean±SD) of Normal Children Group was 52.92 ± 5.72 and CSHQ Score (Mean±SD) of Weak Children Group was 56.23 ± 5.66. Conclusions Weak Children Group had more sleep habit problems than Normal Children Group.	한의학	null		kci_detailed_000246.xml
ART002053292	oai_dc	한방소아과학 수업에서 PBL (Problem Based Learning) 모듈 개발 및PBL 도입을 위한 사전 연구	Preliminary Study for the Development of PBL (Problem Based Learning) Module and the Evaluation of PBL on the Korean Medical Pediatrics Class	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이승연(동의대학교); 유선애(동의대학교)" ]	Objectives The purpose of this study is to examine the development of PBL Module and the possibility of the evaluation on the Korean medical Pediatrics class. Methods In this study, we examined the 32 case reports (four teams for three years) which were made by the Korean medicine school 4th year students, who attended the discussion class. The student read the given materials and identified the purpose of the subjects and selected the learning issues, investigated them. After then they discussed the subjects and made the reports. Results The learning issues by students were similar, the students worked to study them with research papers, books, internet materials and personal subjects. After class, the students showed the change of their thoughts and they could accept the other one. Conclusions This study suggests it is possible that the development of PBL Module and the evaluation on the Korean medical Pediatrics Class.	한의학	null		kci_detailed_000246.xml
ART002053305	oai_dc	자폐스펙트럼장애의 침치료에 대한 최근 임상 연구 동향- RCT 중심으로 -	Recent Clinical Research on Effect of Acupuncture for Autism Spectrum Disorder	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이지나(경희대학교 한의과대학 소아과학교실); 이선행(경희대학교 한의과대학 임상한의학과 소아과학교실); 이진용(경희대학교)" ]	Objectives The purpose of this study is to investigate recent clinical studies on effect of acupuncture for Autism Spectrum Disorder in other countries. We have analyzed the studies on effect of acupuncture for Autism Spectrum Disorder within randomized controlled trail (RCT) for 6years (from 2010 to 2015). Methods The search database includes Medline, Embase, Cochrane library and CNKI (China National Knowledge Infrastructure). To narrow the search, the following key search terms were used: 'autism or ASD or Asperger’s Syndrome or pervasive developmental disorder, acupuncture'. The search was limited to the publication date from 2010 to 2015. 7 control studies in Medlin, Embase, Cochrane library and 5 control studies in CNKI were selected for analysis. Results and Conclusions 1. The acupuncture and rehabiliation treatment is more effective than only acupuncture treatment. Especially, Retention of needling is helpful. 2. It is necessary to set up standard scale in assessment of ASD patients and serum arginine-vasopressin (AVP) can be substitution. 3. Head acupuncture and tongue acupuncture is effective for ASD.	한의학	null		kci_detailed_000246.xml
ART002053300	oai_dc	하태독법 중 황련감초법이 DNFB로 유발된 NC/Nga 생쥐의 아토피 피부염에 미치는 영향	The Effects of Hataedock on 2,4-dinitrofluorobenzene Induced Atopic Dermatitis Like Skin Lesion in NC/Nga Mice	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "차호열(부산대학교 한방병원 한방소아과); 안상현(부산대학교 한의과학연구소); 정아람(부산대학교 한방소아과); 천진홍(부산대학교 한의학전문대학원 임상의학부, 부산대학교 한방병원 한방소아과); 박선영(세명대학교); 김기봉(부산대학교)" ]	Objectives Hataedock is the treatment that dispels toxic heat and meconium gathered at the fetus for the new born baby by orally administered herbal extracts. The purpose of this study was to evaluate whether Hataedock alleviate inflammatory skin damages in AD-induced NC/Nga mice through regulating of skin barrier maintain and Th2 differentiation. Methods We established an AD model in the 3-week-old NC/Nga mice through the repeated application of DNFB (dinitrochlorobenzene) on days 28, 35, 42 after Hataedock treatment which was orally administered. We identified the changes of skin barrier and Th2 differentiation through the histological and immunohistochemical changes of protein kinase C (PKC), interleukin (IL)-4, degranulated mast cell, Substance P and MMP-9. Results Our results suggested that Hataedock treatment significantly down-regulated levels of PKC by 82% (p < 0.001), as well as IL-4 by 56% (p < 0.001). Hataedock also suppressed mast cell infiltration, ear edema formation. and Substance P in the tissue of NC/Nga mice were decreased by 57% (p < 0.001), and MMP-9 by 55% (p < 0.001). Conclusions These results suggest that Hataedock alleviates AD through the down-regulation of PKC and Th2 cytokines, which are involved in the initial steps of AD development. Hataedock have potential application for the treatment of AD.	한의학	null		kci_detailed_000246.xml
ART002053302	oai_dc	강직성 뇌성마비의 침자치료에 대한 문헌고찰 - 최근 중의잡지를 중심으로 -	A Literature Study on Acupuncture for Spastic Cerebral Palsy	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "유선애(동의대학교); 조성우(동의대학교); 이승연(동의대학교 한의과대학 한방소아과학교실)" ]	Objectives The purpose of this study is to look into the methods of acupuncture for spastic cerebral palsy. Methods 27 cases of the clinical literature were selected from 43 studies about cerebral palsy and spastics. Theses literature were published between the January 2010 to September 2015 by using the China Academic Journal (CAJ) of China National Knoweldge Infrastructure (CNKI). Results Most studies mentioned the effect of acupuncture (scalp, general) or acupoint-injection, derma needle, warm acupoint. It was more effective with other herbal complex rehabilitation therapy such as acupuncture, physical therapy occupational therapy, rehabilitation, and the complex speech therapy than just the herbal therapy alone. Acupuncture of acupoint-injection has overall 86～96% of rehabilitation rate. The acupuncture was often used with the general acupuncture and scalp acupuncture. Commonly used major acupuncture points were sishencong (四神總), bohui (百會), yundongqu (運動區), and pinghengqu (平衡區), Li11, Li04, Gb39, St41. The main acupoint-injection points were fengchi (Gb21) and jiexi (St41). For the injection, brain actiator, astragalus injection, cerebroprotein hydrolysate, Vit B1, Vit B2 were commonly used. Conclusion Acupuncture and acupoint-injection have been shown as an effective treatment on spastic cerebral palsy. The acupuncture was used often with the general acupuncture and scalp acupuncture all together.	한의학	null		kci_detailed_000246.xml
ART002053294	oai_dc	호마자 추출물이 NC/Nga 생쥐의 아토피 피부염에 미치는 영향	Therapeutic Effects of Sesamum Indicum Extracts on Atopic Dermatitis-Like Skin Lesions of NC/Nga Mouce	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김윤희(대전대학교); 이혜림(가천대학교)" ]	Objectives The purpose of this study is to investigate the effects of Sesamum indicum extracted (SEI) on atopic dermatitis in an in-vitro and in-vivo experiment using a MC/9 murine mast cells and a NC/Nga mouse. Methods In-vitro experiment, IL-4, IL-5, IL-6, IL-13, TNF-α and GM-CSF mRNA expression were evaluated by Real-time PCR, IL-13, MIP-1α production by ELISA and manifestations of NFAT-1, NFAT-2, c-jun, c-fos, NF-κB p65 transcription factors by western blotting. In-vivo experiment, we measured WBC, Eosinophil, Neutrophil, and serum IL-5, IL-13 in NC/Nga atopic dermatitis mouse, IL-5, IL-13, IFN-γ, IL-4 in the spleenocyte culture supernatant by ELISA, the absolute cell numbers of CD4+, CD8+, +Gr-1+CD11b, B220+CD23+ in the axillary lymph node (ALN), peripheral blood mononuclear cells (PBMCs) and dorsal skin tissue, IL-5, IL-13 by Real-time PCR, the distribution of tissue inflammation and cellular infiltration by H&E and toluidine blue. Results SEI decreased IL-4, IL-5, IL-6, IL-13, GM-CSF, TNF-α mRNA expression, IL-13, MIP-1α production and the expression of transcription factors including NFAT-1, c-jun, NF-κB p65 in MC/9 murine mast cells. SEI orally administration decreased cell number of WBC, Eosinophil, the level of serum IgE, total cell number of ALN and dorsal skin tissue, absolute cell number of CD4+, CD8+, B220+CD23+ in the ALN. SEI orally administration also increased absolute cell number of CD8+/CD3+ and decreased Gr-1+/CD11b+ in PBMCs, decreased CD4+ in dorsal skin tissue, inhibited IL-5, IL-13 mRNA expression. Infiltration levels of inflammatory immune cells, mast cells and thickness of epidermis decreased in dorsal skin tissue. Conclusions SEI can regulate allergic inflammatory response suppressed the gene expression and production of cytokines that mediate allergic reactions, and will be able to be effectively utilized in the treatment of atopic dermatitis future.	한의학	null		kci_detailed_000246.xml
ART002024246	oai_dc	금은화 추출물의 항산화, 항염증 효과가 Dextran Sulfate Sodium으로 유도된 생쥐의 궤양성 대장염에 미치는 영향	The Anti-oxidative and Anti-inflammatory Effect of Lonicera Japonica on Ulcerative Colitis Induced by Dextran Sulfate Sodium in Mice	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "차호열(부산대학교 한방병원 한방소아과); 정아람(부산대학교); 천진홍(부산대학교); 안상현(동국대학교); 박선영(세명대학교); 김기봉(부산대학교)" ]	Objectives This study was to investigate the anti-oxidative and anti-inflammatory effect of Lonicera japonica water extracts (LE) on Ulcerative Colitis Induced by DSS (Dextran Sulfate Sodium) in Mice Methods Colitis was induced by DSS in Balb/c mice. The sample group was divided into three. The mice in control group were not inflammation-induced. The pathological group was composed of untreated colitis elicited mice. The experimental group was administered Lonicera japonica water extracts (LE) after colitis elicitation. The effects on ulcerative colitis were evaluated the anti-oxidant effect, inhibition of COX-2 mRNA expression, the morphological change of colonic mucosa, decrease effect of HSP 70 and COX-2 in mucosa. Results The SOD ability of LE was dose-dependently increased and the LPS-induced COX-2 mRNA expression of LE was dose-dependently decreased. LE showed the protective effects on DSS-induced experimental colitis. LE inhibited shortening of colon length, the hemorrhagic erosion in colonic mucosa. LE also showed the decrease effect for HSP70 and COX-2 in mucosa. Conclusions The current results demonstrate the clinical utility of LE in traditional medicine and indicate the possible treatments for ulcerative colitis from natural products. Further investigations for exact mechanisms will be needed.	한의학	null		kci_detailed_000246.xml
ART002024250	oai_dc	해표이진탕이 기도 뮤신의 분비, 생성 및 유전자 발현에 미치는 영향	Effect of Haepyoijin-tang on Airway Mucin Secretion, Production, Gene Expression and Hypersecretion of Mucus	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "석연희(동국대학교); 민상연(동국대학교); 김장현(동국대학교)" ]	Objectives In this study, effects of haepyoijintang (HIJ) on the increase in airway epithelial mucosubstances of rats and ATP-, PMA-, EGF- or TNF-α-induced MUC5AC mucin production and gene expression from human airway epithelial cells were investigated. Methods Hypersecretion of airway mucus was induced by exposure of rats to SO2 during 3 weeks. Effect of orally-administered HIJ during 2 weeks on increase in airway epithelial mucosubstances from tracheal goblet cells of rats was evaluated using histopathological analysis after staining the epithelial tissue with PAS-alcian blue. Possible cytotoxicity of HIJ was evaluated by examining the potential damage of kidney and liver functions by measuring serum GOT/GPT activities and serum BUN and creatinine concentrations of rats and the body weight gain during experiment, after administering HIJ orally. At the same time, the effect of HIJ on ATP-, PMA-, EGF- or TNF-α-induced MUC5AC mucin production and gene expression from human airway epithelial cells (NCI-H292) were investigated. Confluent NCI-H292 cells were pretreated for 30 min in the presence of HIJ and treated with ATP (200 μM), PMA (10 ng/ml), EGF (25 ng/ml) or TNF-α (0.2 nM) for 24 hrs, to evaluate the effect of HIJ both on ATP-, PMA-, EGF- or TNF-α-induced MUC5AC mucin production using enzyme-linked immunosorbent assay (ELISA) and on gene expression by the same inducers using reverse transcription-polymerase chain reaction (RT-PCR). Results (1) HIJ decreased the amount of intraepithelial mucosubstances of trachea of rats. (2) HIJ did not show renal and hepatic toxicities and did not affect body weight gain of rats during experiment. (3) HIJ significantly inhibited ATP-, PMA-, EGF-, and TNF-α-induced MUC5AC mucin productions from NCI-H292 cells. (4) HIJ significantly inhibited ATP-, PMA-, EGF-, and TNF-α-induced MUC5AC mucin gene expression from NCI-H292 cells. Conclusions The result from the present study suggests that HIJ might control the production and gene expression of airway mucin observed in various respiratory diseases accompanied by mucus hypersecretion and do not show in vivo toxicity to liver and kidney functions after oral administration. Effect of HIJ with their diverse components should be further investigated using animal experimental models that can reflect the pathophysiology of airway diseases through future studies.	한의학	null		kci_detailed_000246.xml
ART002024228	oai_dc	소아 천식 치료의 국외 보완대체의학 임상 연구 동향	The Trends in Foreign Clinical Trials for Pediatric Asthma in Complementary and Alternative Medicine	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "방미란(동국대학교 한의과대학 소아과교실); 김장현(동국대학교); 민상연(동국대학교)" ]	Objectives The purpose of this study is to analyze the trends in foreign clinical trials for pediatric asthma in complementary and alternative medicine (CAM) Methods We reviewed 31 randomized controlled trials (RCT) for pediatric asthma treatment in CAM published from 2005 to 2015 in PubMed and analyzed their treatments, compounds of herbal medicines, acupoints, methods of assessment, and treatment results. Results The treatments used in the studies were herbal medicines, acupuncture, acupoint application, breathing training, supplement, normocaloric diet, yoga, massage therapy, and art therapy. The frequently used herbs were Asari Herba Cum Radix (細辛). Ephedrae Herba (麻黃), Astragali Radix (黃芪). The most common acupoints were Feishu (肺兪, BL13). The methods of assessment in pediatric asthma were symptom scale, questionnaire of Quality of Life, lung function test, laboratory studies, and medication usage. In 28 out of 31 studies, treatment group gets better than non-treated group. Conclusions This study shows that CAM is effective in treating pediatric asthma. More clinical studies using objective outcome measures are needed to prove its efficacy clearly.	한의학	null		kci_detailed_000246.xml
ART002024233	oai_dc	학령기 아동에서 어머니-아동 기질 관계와 양육스트레스 연구	Relationships between Mother-Child Temperamental Interactions and Parenting Stress in Korean School-Aged Children	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "유경(밝은언어심리센터); 김락형(우석대학교); 유승택(원광대학교)" ]	Objectives The purpose of this study was to investigate the relationships between mother's and child's temper and parenting stress Methods One hundred twenty healthy mothers (above 20 yrs old) who has a school-aged child (7-11 yrs old) participated after informed consent. The temperament of the children was analyzed by the Junior Temperament and Character Inventory 7-11 (JTCI 7-11) by their mothers. The temperament of the mothers was analyzed by the Temperament and Character Inventory-Revised Short (TCI-RS) and the mother's parenting stress was analyzed by the Korean Parenting Stress Index (K-PSI). The relationships between mothers' and child's temperament and parenting stress were assessed using the Pearson correlation coefficient and multiple regression test. Results There were significant correlations between maternal temperaments and child's temperaments and maternal parenting stress. There was a positive correlation between mother's harm avoidance characteristic, child's novelty seeking degree and parenting stress. On the other hand, there was a negative correlation between child's persistence and parenting stress. In addition, interactions between child and mother temperament dimensions predicted higher levels of parenting stress. Parenting stress was higher in the group of high mother's harm avoidance with child's high novelty seeking and high mother's harm avoidance with low child's persistence. Conclusions These results are showing that there are significant relationships between mother and child temperament and parenting stress in mothers with school-aged children.	한의학	null		kci_detailed_000246.xml
ART002024241	oai_dc	일본에서 소아질환에 적용하는 한약치료에 대한 문헌고찰	A Literature Study of Kampo Drug Treatment for Children in Japan	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "지현우(세명대학교 한의학과); 송창은(세명대학교 한의학과); 성현경(세명대학교)" ]	Objectives This research aimed to analyze studies on pediatric disease treated by kampo drug, kind of kampo drug used in children, treatment period, and the result of kampo drug treatment for children in Japan. Methods We got 263 search result with searching word ‘kampo medicine’ and ‘小兒’, ‘children’, ‘乳兒’ in J-stage. We selected 34 articles among them which were related to objective of research to analyze studies by type of pediatric disease treated with kampo drug, kinds of kampo drug for each disease, treatment period and result of kampo drug treatment for children. We considered frequency of kampo drug use & pediatric disease treated with kampo drug and significance of research. Results According to analyzed results, respiratory diseases are the most frequent diseases that are healed by kampo drug. Next sequenced diseases are skin disease. In Kind of kampo drug for pediatric disease. Goreisan (五苓散) and Shosaikoto (柴胡桂枝湯), Shokenchuto (小建中湯) are used frequently. Also, various disease treated with kampo drug were improved. Conclusions Japanese Doctors consider the Kampo drug is safe and has a lot of merit compared to modern medication. Especially for symptom with unknown origin & immune diseases such as upper respiratory tract infections. Referring to clinical cases of kampo drug in Japan, we will use kampo drug for various pediatric diseases in future.	한의학	null		kci_detailed_000246.xml
ART002024237	oai_dc	길랑바레 증후군의 한방치료에 관한 고찰 –중의학 저널을 중심으로–	A Literature Study on Treatment of Guillain-Barre Syndrome Based on Traditional Chinese Medicine Journals	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김형중(경희대학교 한의과대학 한방소아과); 이은주(경희대학교 한의과대학 한방소아과); 이선행(강동경희대학교병원); 장규태(경희대학교)" ]	Objectives The purpose of this study is to analyze Korean medicine treatment of guillain-barre syndrome based on TCM (Traditional Chinese Medicine) Journals. Methods 12 control studies and 28 case studies in CNKI (China National Knowledge Infrastructure) were selected for analysis. Results and Conclusions 1. In control studies, most studies have studied western medicine (Control) versus western medicine + TCM (Intervention group). The intervention group had significantly better results than that of the control group. 2. In case studies, syndrome differentiations related to dual deficiency of qi and blood are common. Every syndrome differentiations has deficiency syndrome. 3. The most commonly used acupoints are LI11, ST36, LI4 and GB34. 4. The most commonly used meridians are large intestine meridian and stomach meridian.	한의학	null		kci_detailed_000246.xml
ART001995461	oai_dc	金水六君煎이 이산화황으로 유발된 흰쥐의 호흡기 점액 및 뮤신생성에 미치는 영향	Effect of Geumsuyukgunjeon on Airway Mucus Secretion and Mucin Production	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김은진(동국대학교 한의과대학 소아과학교실); 민상연(동국대학교); 김장현(동국대학교)" ]	Objectives In this study, effect of Geumsuyukgunjeon (GYJ) on the increase in airway epithelial mucosubstances of rats with acute bronchitis and EGF-induced MUC5AC mucin production from human airway epithelial cells were investigated. Materials and Methods Hypersecretion of airway mucus was induced by exposure of rats to SO2 during 3 weeks. Effect of orally-administered GYJ during 2 weeks on increase in airway epithelial mucosubstances from tracheal goblet cells of rats was assesed using histopathological analysis after staining the epithelial tissue with PAS-alcian blue. Possible cytotoxicity of GYJ was assessed by examining the potential damage of kidney and liver functions by measuring serum GOT/GPT activities and serum BUN and creatinine concentrations of rats and the body weight gain during experiment, after administering GYJ orally. Effect of GYJ on EGF-induced MUC5AC mucin production from human airway epithelial cells (A549) was investigated. Confluent A549 cells were pretreated for 30 min in the presence of GYJ and treated with EGF (25 ng/ml) for 24 hrs, to assess the effect of GYJ on EGF-induced MUC5AC mucin production using enzyme-linked immunosorbent assay (ELISA). Results (1) GYJ decreased the amount of intraepithelial mucosubstances of trachea of rats. (2) GYJ did not show kidney and liver toxicities and did not affect body weight gain of rats during experiment. (3) GYJ significantly inhibited EGF-induced MUC5AC mucin production from A549 cells. Conclusions The result from the present study suggests that GYJ might control both the mucus hypersecretion in vivo and do not show in vivo toxicity to liver and kidney functions after oral administration and the production of pulmonary mucin.	한의학	null		kci_detailed_000246.xml
ART001995466	oai_dc	Pubmed로 검색한 소아 천식의 침술 및 혈위약물요법 치료에 관한 문헌고찰	A Literature Study of Oriental Medicine Therapy for Pediatric Asthma Mainly about Acupuncture and Acupoint Application in Pubmed	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "송창은(세명대학교); 지현우(세명대학교); 이학경(세명대학교); 성현경(세명대학교)" ]	Objectives Asthma is an allergic disease that frequently occurs in children. This study aims to research acupuncture and acupoint-application treatment of pediatric asthma. Methods We got 53,653 search results with searching word ‘child’ ‘children’ ‘pediatric’ ‘juvenile’ ‘adolescence’ ‘baby’ ‘infant’ ‘asthma’ in Pubmed and got 147 results among them with searching word ‘acupuncture’ ‘acupoint application’. We selected 13 articles among them which were seem to be related to this study. We classified these studies according to the type of study, the treatment methods and treatment outcomes. Results There were few studies about acupuncture and acupoint application on pediatric asthma. According to current research, conducting acupuncture and acupoint application treatment on pediatric asthma patient is recommended. Especially, acupoint application and laser acupuncture treatment were important to consider as treatment options on pediatric asthma patients for non-invasive way and less painful to children. Conclusions For the study on acupuncture and acupoint application treatment in pediatric asthma, it is necessary that we conduct research on various merit of acupuncture. More clinical data would be needed to prove the effects of acupuncture and acupoint application treatment in pediatric asthma.	한의학	null		kci_detailed_000246.xml
ART001995457	oai_dc	DNCB로 유발된 생쥐의 알레르기성 접촉피부염에 선태가 미치는 영향	Effects of Cicadae Periostracum (CP) in Allergic Contact Dermatitis (ACD) Induced by DNCB in Mice	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김빛나래(동신대학교 한의과대학); 채중원(동신대학교)" ]	Objectives In the theory of Korean Medicine, Cicadae Periostracum (CP) has been used to treat skin diseases such as inflammatory dermatitis, tetanus and pruritus. CP can reduce heat and disperse wind. In prior studies, anti-allergic effect and anti-inflammatory effect of CP were reported. However, there has been no report regarding the correlation of CP and allergic contact dermatitis (ACD). This study was performed to show the effects of CP in ACD induced by 2,4-dinitrochlorobenzene (DNCB) in mice. Methods In this experiment, the effects of CP on biological changes were measured, such as changes in ear and spleen weight, ear and dorsum skin thickness, clinical aspect on the dorsum skin and histological changes. The effect of proliferation rate of splenocytes was also investigated in vitro and vivo study. Results In results, CP application (CPA) group and CP application and administration (CPAA) group were significantly restrained in ear weight gain and increase in ear and dorsum skin thickness compared to the control group. In addition, CPA and CPAA group showed diminished erythema, desquamation, bloodstain, and marks. Also, the histological assessment showed that CP treatement diminished thickness of epidermis, hyperkeratosis, pigmentation and parakeratosis. Conclusions In conclusion, these data suggest that CP can decrease symptoms of ACD.	한의학	null		kci_detailed_000246.xml
ART001995464	oai_dc	지방전구세포와 고지방식이비만마우스에서 가미곽향정기산의 전탕액과 발효액의 항비만효과	The Antiobese Effects of Gamikwakhyangjungkisan and Fermented GamiKwakhyangjungkisan in Preadipocytes and Mice Fed High Fat Diet	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김주희(원광대학교 한의과대학 소아과학교실); 박은정(원광대학교)" ]	Objectives This experimental study was designed to investigate the antiobese effects of Gamikwakhyangjungkisan and Fermented GamiKwakhyangjungkisan. Methods The cellular lipid contents were assessed by Oil-Red-O staining. The expression of PPARγ and C/EBPα were determined by real time RT-PCR and western blotting. In addition, body weight gain and serum lipid levels were measured in the mice with obesity induced by the high fat-diet for four weeks. Results Gamikwakhyangjungkisan and Fermented GamiKwakhyangjungkisan is reduced 3T3-L1 cells’ differentiation and the expressions of PPARγ and C/EBPα in high concentration group. High-fat diet + Fermented GamiKwakhyangjungkisan group significantly reduced body weight gain. High-fat diet + Fermented GamiKwakhyangjungkisan group significantly increased HDL-cholesterol contents and reduced LDL-cholesterol contents. Furthermore, Fermented GamiKwakhyangjungkisan is excellent antiobese effects than Gamikwakhyangjungkisan. Conclusions These results demonstrate that Gamikwakhyangjungkisan and Fermented GamiKwakhyangjungkisan exerts antiobese effect in 3T3-L1 cells and mice fed high fat diet. Furthermore, Fermented GamiKwakhyangjungkisan is excellent antiobese effects than Gamikwakhyangjungkisan.	한의학	null		kci_detailed_000246.xml
ART001995458	oai_dc	청소년의 신체활동이 성장에 미치는 영향	The Effect of Physical Activities on the Growth Indices in Adolescents	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이혜림(가천대학교)" ]	Objectives The purpose of this study is to investigate the relationship between physical activity and growth indices. Methods 5963 of 12 years old adolescents were participated in the 10th Korea Youth Risk Behavior Web-Based Survey (KYRBWS-V) project in 2014. These data was analyzed to show the relationship between physical activity and height, BMI. Results According to the Physical Activity guidelines, the mean height was higher in the each male and female group with ‘moderate physical activity for at least 60 min ≥ 7 days/week’, ‘vigorous physical activity ≥ 3 days/week’, and ‘muscle-strengthening activity ≥ 3 days/week’ compare to the group who did not. The mean BMI was lower in the male group of ‘sitting for watching TV or computer, etc on a weekday ＜ 3 hr/day’ compare to group who did not. Conclusions These results showed that physical activity in adolescence is correlated to growth. Therefore, this research can be one of the reference data to show the proper physical activity is important in the growth.	한의학	null		kci_detailed_000246.xml
ART001995556	oai_dc	식물성에스트로겐 작용이 보고된 한약재에 관한 고찰	The Review of the Herbal Medicines with Phytoestrogenic Effect	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이선행(강동경희대학교병원); 김형중(경희대학교 한의과대학 한방소아과); 이은주(경희대학교 한의과대학 한방소아과); 장규태(경희대학교)" ]	Objectives Medical plant has a big role in Herbal Medicines, and most medical plant has phytoestrogens. Therefore some estrogenic effects have been reported in a lot of Korean Medicine literature. Phytoestrogens should be used carefully in children. The objective of this study is to identify reported phytoestrogenic effects in Herbal Medicines and to evaluate the characteristics of the phytoestrogens in Herbal Medicines. Methods A literature search was done with using 8 databases with a limit of reports until 12/31/2013. The estrogenic effects were summarized by each individual Korean Medicine. The frequency of the phytoestrogens was also investigated depending on the Korean medical categorization by the treatment effect. Results and Conclusions Phytoestrogenic effects were reported in 89 Herbal Medicines. Phytoestrogens were act bidirectionally, and the effect was fairly weak compared to estrogen. Phytoestrogenic effect was variable on different cells and tissues. The most frequent phytoestrogenic effect was in tonifying and replenishing medicinal, the following orders were heat-clearing, exterior-releasing, and blood-activating and stasis-dispelling medicinal. Phytoestrogens were not reported in dampness-resolving, digestant, orifice-opening, emetic medicinal.	한의학	null		kci_detailed_000246.xml
ART001906730	oai_dc	Sensitiv ImagoTM, 양도락을 이용한 Duchenne Muscular Dystrophy 환아 1례의 검사 결과 보고	A Case Report : The Measurement Results of Duchenne Muscular Dystrophy Patient Using Sensitiv ImagoTM and Ryodoraku	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "한주희(경희대학교 한방소아과); 김덕곤(경희대학교); 이진용(경희대학교)" ]	ObjectivesThe purpose of this study is to report the measurement results of Duchenne Muscular Dystrophy (DMD) inPatient Using Sensitiv ImagoTM (SI) and Ryodoraku. MethodsWe conducted SI test and Ryodoraku test to a 7-year-old DMD patient who visited to Oriental pediatrics,Kyung Hee Medical Center. ResultsWe obtained SI and Ryodoraku test results from a DMD patient. ConclusionsFurther study with more samples is necessary to establish accuracy of SI in clinical use.	한의학	null	http://dx.doi.org/10.7778/jpkm.2014.28.3.074	kci_detailed_000246.xml
ART001906691	oai_dc	한약 복용 후 발생한 유해사례에 대한 연구 - 소아ㆍ청소년을 중심으로	A Study of Adverse Events that Occurred after Taking Herbal Medicine - Focused on Children and Adolescents	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이지홍(동의대학교 한의과대학 소아과학교실); 유선애(동의대학교); 이승연(동의대학교)" ]	ObjectivesThe purpose of this study is to investigate the incidence and clinical features of adverse events associated withherbal medicine, and to analyze their causality and severity. MethodsThis study was carried out from 159 children and adolescents who took herbal medicine in the Department ofPediatrics, OO Korean Medical Hospital from december, 2013 to april, 2014. The data was collected by survey inperson or telephone. The World Health Organization (WHO)-Uppsala Monitoring Center (UMC) criteria was usedto analyze causality for each adverse events. Results1. 207 cases were surveyed from 159 children and adolescents who took one or more kinds of herbal medicine. 2. A total of 12 general adverse events (5.8%) were reported from the study. Among these adverse events, 8 cases(3.9%) were associated with herbal medicine. 3. Gastro-intestinal system disorders were most frequently reported (70%) as adverse events, which is followed bypsychiatric disorders (15%), skin and appendages disorders (10%), urinary system disorders (5%). 4. The most common clinical symptom was abdominal pain (20%), followed by diarrhea (15%), loose stools(10%), vomiting (10%) and borborygmus (10%). 5. The severity of adverse drug reactions was mostly mild (87.5%), and moderate (12.5%). There was no severecase. ConclusionsThe adverse events from herbal medicine on children and adolescents were mostly minor, most of them couldcontinue herbal medicines.	한의학	null	http://dx.doi.org/10.7778/jpkm.2014.28.3.001	kci_detailed_000246.xml
ART001906704	oai_dc	영유아 아토피피부염 환자 69명의 한의학적 치료효과에 대한 후향적 연구	Retrospective Study about the Effectiveness of a Korean Medicine Treatment on 69 Infant and Young Child Atopic Dermatitis Patients	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "민들레(프리허그 한의원); 한명화(프리허그한의원); 박건(프리허그한의원); 서산(프리허그한의원); 한수련(프리허그한의원)" ]	ObjectivesThe purpose of this study is to report the effectiveness of Korean medicine treatment on 69 infant and youngchild atopic dermatitis patients. Methods69 infants and young child atopic dermatitis patients who had visited oriental medical clinics from 2011.1.9 to2012.1.31 were studied. All of them were continually treated for 3 to 9 months, and were analyzed by ObjectiveSCORAD Index (OSI). A detailed analysis of OSI was done according to gender, age, using of topical steroidointment, family history of atopic disease, treatment period, and intensity. Results1. Male and female percentage of the study group was 56.5%: 43.5%. The average period of treatment was 6.09months. 71.0% used topical steroid ointment, and 65.2% had family history of atopic disease. 2. The average period of treatment was significantly longer in patients who used topical steroid ointment, or whohad family history of atopic disease. 3. 95.7% of total patients reported decrease in OSI score at the final visit. OSI was significantly lowered after3, 6, and 9 months of treatment. The longer period of treatment, the lower average post-treatment OSI. 4. 85.5% of the study group had severe dermatitis, and 14.5% was moderate case based on the OSI intensityassessment at initial visit. These percentages got changed at the final visit as 34.8% of severe, 58.0% ofmoderate, and 7.2% of mild cases. The average treatment period of patients who were diagnosed as severe atthe initial visit was 6.18 months, and their final OSI improvement rate was 39.58%. 58% of them wereimproved to be mild or moderate at the final visit. ConclusionThe Korean medicine treatment is effective in treating infant and young child atopic dermatitis patients. Therewas significant decrease in OSI score after 3, 6, and 9 months of treatment. The difference increase with thetreatment period.	한의학	null	http://dx.doi.org/10.7778/jpkm.2014.28.3.017	kci_detailed_000246.xml
ART001906724	oai_dc	Anti-inflammatory Activities of GyejigaChulBuTang on Lipopolysaccharide-stimulated RAW264.7 Cells	Anti-inflammatory Activities of GyejigaChulBuTang on Lipopolysaccharide-stimulated RAW264.7 Cells	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "정민정(우석대학교); 이승연(동의대학교); 유선애(동의대학교); 강경화(동의대학교)" ]	ObjectivesGyejigaChulBuTang (GCBT) is a prescription used to treat acute and chronic arthritis in Korea, China, andJapan. This study assessed the anti-inflammatory and anti-oxidant activities of GCBT on lipopolysaccharide(LPS)-stimulated RAW264.7 macrophage cells. MethodsRaw264.7 cells were pretreated with or without GCBT for 1 hour prior to incubation with LPS. Anti-inflammatory activity of GCBT was evaluated with reference to gene expression and production levels ofproinflammatory cytokines (TNFα, IL-1β, IL-6, GM-CSF and INFγ) and inflammatory mediators (iNOS, COX-2,NO and PGE2). In addition, intracellular ROS generation and signal transduction of MAPK family, PI3K/Akt andIκBα/NFκB was investigated. ResultsPrior treatment with GCBT inhibited elevation of TNFα, IL-1β, IL-6, GM-CSF, INFγ, NO and PGE2, togetherwith their cognate mRNAs in a dose-dependent manner. Intracellular ROS contents were similarly reduced. Theseeffects were due to inhibition of LPS-induced phosphorylation of MAPK family, PI3K/Akt and IκBα as well asnuclear translocation of NFκB. ConclusionsGCBT suppresses pro-inflammatory mediators. GCBT has potential in the treatment of juvenile rheumatoidarthritis associated with inflammation.	한의학	null	http://dx.doi.org/10.7778/jpkm.2014.28.3.047	kci_detailed_000246.xml
ART001906735	oai_dc	Sensitiv ImagoTM 측정에 의한 틱 장애 환아의 검사 결과 보고	Report of Sensitiv ImagoTM Test Results in Tic Disorder Children	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김민주(경희대학교 한의과대학 한방소아과); 김덕곤(경희대학교); 이진용(경희대학교)" ]	ObjectivesThe purpose of this study is to report test results in eight tic disorder children using Sensitiv ImagoTM. MethodsEight tic disorder children were tested using Sensitiv ImagoTM. Also, they were diagnosed with tic disorders byDSM-Ⅳ (Diagnostic and Statistical Manual of Mental Disorders, 4th edition) and we evaluated tic disorder cases byYale Global Tic Severity Scale (YGTSS). ResultsIn 8 cases, 1 case was transient tic disorder, 3 cases were Tourette’s disorder and 4 cases were unspecified ticdisorder. In the result of Sensitiv ImagoTM, 4 cases showed the lowest score at filter #5* and 4 cases showed thelowest score at filter #6* in [Express Monitoring] of [Review of System Disorders of Homeostasis]. Filter #5includes urogenital organs, liver, gallbladder, kidneys, urinary bladder and ureter and Filter #6 stands for organsof immune and respiratory systems. ConclusionWe report test results in eight tic disorder children using Sensitiv ImagoTM. Further studies about the principle,repeatability, reproducibility of Sensitiv ImagoTM are needed.	한의학	null	http://dx.doi.org/10.7778/jpkm.2014.28.3.085	kci_detailed_000246.xml
ART001906712	oai_dc	비만세포에서 連翹 추출물의 Th2 사이토카인 발현 및 신호전달 기전 억제효과	The Suppressive Effect of Th2 Cytokines Expression and the Signal Transduction Mechanism in MC/9 Mast Cells by Forsythiae Fructus Extracts	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이진화(대전대학교 한의과대학 소아과학교실); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]	ObjectivesForsythiae Fructus treatment has been used for inflammatory and allergic diseases in Korean Medicine. Nevertheless, the mechanism of action and the cellular targets are not understood well. The pathogenesis of allergicdiseases are associated with Th2 cytokines such as IL-13, MIP-1α, IL-13, IL-5, GM-CSF, IL-4, TNF-α and IL-6,which are secreted by the mast cells. This study was conducted to investigate the effects of Forsythiae Fructusextracts (FF) on Th2 cytokines expression and signal transduction in MC/9 mast cells. MethodsIn the study, MC/9 mast cells were stimulated with DNP-IgE for 24 hours and then treated separately with CsA10 ㎍/㎖ and varying doses of FF for one hour. MC/9 mast cells stimulated with DNP-IgE was the control group,a treatment with CsA was the positive control group and a treatment with varying doses FF was the experimentalgroups. The mRNA levels of IL-13, IL-5, GM-CSF, IL-4, TNF-α, IL-6 were analyzed with Real-time PCR. Thelevels of IL-13, MIP-1α were measured using enzyme-linked immunosorbent assays(ELISA). NFAT, AP-1 and NF-κB p65 were examined by Western blot analysis. Results1. FF were observed to suppress the mRNA expression of IL-13, IL-5, GM-CSF, IL-4, TNF-α, IL-6 in comparisonto DNP-IgE control group. 2. FF also has inhibited the IL-13, MIP-1α production significantly in comparison to DNP-IgE control group. 3. Western blot analysis of transduction factors involving Th2 cytokines expression has revealed a prominentdecrease of the mast cell specific transduction factors including NFAT-1, NFAT-2, c-Jun, and NF-κB p65 butc-Fos. ConclusionsIn conclusion, the anti-allergenic activities of FF may be strongly related to the regulation of transcription factorsNFAT-1, NFAT-2, c-Jun, and NF-κB p65 causing inhibition of Th2 cytokines in mast cells.	한의학	null	http://dx.doi.org/10.7778/jpkm.2014.28.3.031	kci_detailed_000246.xml
ART001906726	oai_dc	山楂가 DNCB로 유발된 생쥐의 알레르기성 접촉피부염에 미치는 영향	Effects of Crataegus Pinnatifida (CP) on Allergic Contact Dermatitis (ACD) Induced by DNCB in Mice	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "유수향(동신대학교); 채중원(동신대학교)" ]	Allergic contact dermatitis (ACD) is a type IV delayed hypersensitivity reaction that results from exposures andsubsequent sensitization to an environmental chemical. Crataegus Pinnatifida (CP) is commonly used to improvespleen function, remove retention of food, and promote blood circulation. This study is designed to investigate theeffects of CP on ACD induced by 2,4-dinitrochlorobenzene (DNCB) in mice. In this experiment, the effects of CPon changes in body weights, ear and dorsum skin thicknesses, ear weights, clinical aspects on the dorsum skin,histopathological changes, spleen weights, cytokines were investigated. In addition, the effects on the proliferationrates of splenocytes were also investigated in vivo and vitro study. In results, CP spread (CPS) group and CP spread and administered (CPS+Adm) group showed decrease in spleenweights. In CPS+Adm group, dorsum skin thicknesses were decreased significantly compared to control group. CPtreatment diminished erythema, desquamation and keratosis which were induced by repeated painting of DNCB. In histopathological observation, spongiosis and edema were diminished in CPS and CPS+Adm group. CP led todecrease in the proliferation rates of splenocytes in vivo and vitro. In conclusion, these data suggest that CP can decrease symptoms of ACD, so CP is useful to treat patient withACD.	한의학	null	http://dx.doi.org/10.7778/jpkm.2014.28.3.059	kci_detailed_000246.xml
ART001932517	oai_dc	삼복첩의 장단점에 대한 인식조사와 삼복첩 부작용에 대한 연구	The Study on Investigation of Advantages and Disadvantages of Acupoint Sticking in Dog-Days and Side Effects of Acupoint Sticking in Dog-Days	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김형중(경희대학교 한의과대학 한방소아과); 이은주(경희대학교 한의과대학 한방소아과); 이선행(강동경희대학교병원); 장규태(경희대학교)" ]	ObjectivesThe purpose of this study is to understand what caregivers think advantageous and disadvantageous regardingAcupoint sticking Dog-days. Also, to know whether Acupoint sticking in Dog-days affect vital signs, and toinvestigate if occurrence of side effects are related to application duration, sweat, or compliance to precautionarymeasures. MethodsSurvey has been handed out to parents of the children who took Acupoint sticking in Dog-days. 10 days afterthe first dose was administered, survey was performed to examine any side effect occurrences, characteristics of sweat,duration of application, parents’ thought about this therapy. Also, vital signs were checked before the first dose,and 10 days after to see any differences in vital signs in regards to this therapy. ResultsPreferable opinions about Acupoint sticking in Dog-days are ‘convenient than herbal medications’ (76.5%), ‘lessreluctance of child’ (47.1%), ‘reasonable price’ (20.6%), ‘good effectiveness’ (17.6%), ‘less side effect’ (14.7%), ‘noworry about agrochemicals or heavy metals uptake’ (11.8%). Downsides were ‘difficult to admit to hospital righton the Dog-days’ (73.5%), ‘no conspicuous effectiveness’ (11.8%), ‘expensive’ (5.9%), ‘reluctance of child’ (2.9%). Vital sign differences were minimal when examined before and after Acupoint sticking in Dog-days. Side effectsoccurred 5 times in 34 cases, and they were erythema, itchiness, and hot sensation. There were no scars or blistersreported. All 5 cases were resolved without any interventions within 3 days. ConclusionsAcupoint sticking in Dog-days doesn’t affect vital signs. Severe side effect is rare, reported side effects wererelatively mild, suggesting that it may be safe and well-tolerated. ‘Convenience’ (76.5%) is biggest advantage ofAcupoint sticking in Dog-days and ‘less reluctance of child’ is also big advantage of Acupoint sticking in Dog-days. ‘Difficulty to admit to hospital right on the Dog-days’ (73.5%) is biggest disadvantage of Acupoint sticking inDog-days.	한의학	null		kci_detailed_000246.xml
ART001932488	oai_dc	白鮮皮 추출물이 DNCB로 유발된 NC/Nga 생쥐의 아토피 피부염에 미치는 영향	The Effects of Dictamni Radicis Cortex Extracts on DNCB Induced Atopic Dermatitis-like Skin Lesions of NC/Nga Mouse	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이윤실(대전대학교 한의과대학 소아과학교실); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]	ObjectivesDictamni Radicis Cortex extracts (DRC) has been known to suppress allergic reaction, however the cellulartarget of DRC and its mode of action remain unclear. The purpose of this study is to investigate the effects ofDictamni Radicis Cortex extracts on DNCB induced atopic dermatitis-like skin lesions of NC/Nga mouse. MethodsThis study was designed to investigate the effects of DRC extract in the DNP-IgE-induced activation of MC/9murine mast cell lines in vitro and in the DNCB-induced activation of NC/Nga mouse in vivo. For thisinvestigation, We examined IL-4, IL-5, IL-6, IL-13, TNF-α and GM-CSF mRNA expression by Real-time PCR,IL-13, MIP-1α production by ELISA analysis and manifestations of NFAT1, NFAT2, AP-1 and NF-κB p65transcription factors by western blotting in vitro. Then, we examined WBC, eosinophil and neutrophil in NC/Ngamouse, IL-5, IL-13 in serum, IFN-γ, IL-4 in the spleenocyte culture supernatant, the absolute cell numbers ofCD4+, CD8+, +Gr-1+CD11b, B220+CD23+ in the ALN, PBMCs and dorsal skin, IL-5, IL-13 in the dorsal skin byReal-time PCR and the distribution of mast cells by H&E and toluidine blue. ResultsIn vitro the mRNA expression of IL-4, IL-5, IL-6, IL-13, TNF-α, GM-CSF and IL-13, MIP-1α production byELISA analysis were completely abolished by DRC and the western blot analysis decreased the expression of mastcell-specific transcription factors including NFAT-1, NF-κB p65. In vivo DRC oral adminstration also decreasedthe counts of WBC, eosinophils and inflammatory cytokines such as IL-13 and IgE in the serum. DRC oraladminstration elevated IL-4 level in the spleenocyte culture supernatant. DRC oral adminstration decreased totalALN cells, total skin cells, cell numbers of CD4+, B220+CD23+ in the ALN, +Gr-1+CD11b in the PBMCs andCD4+, CD8+ in the dorsal skin. The mRNA expression of IL-5, IL-13, thickness of epidermis, inflammationimmune cells and mast cells were abolished by DRC in the dorsal skin. ConclusionsHistological examination showed that infiltration levels of immune cells in the skin of AD-induced NC/Ngamouse were much improved by DRC oral adminstration. These results, therefore, suggest that DRC can regulatemolecular mediators and immune cells that are functionally associated with atopic dermatitis induced in NC/Ngamouse, and may play an important role in recovering AD symptoms.	한의학	null		kci_detailed_000246.xml
ART001932498	oai_dc	한방병원에 내원한 소아청소년기 말초성 안면마비 환자 284례를 통한 임상적 고찰	A Clinical Study on Children and Adolescents Who Visited the Hospital of Korean Medicine for 284-Peripheral Facial Palsy	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "강기연(대전대학교부속한방병원); 이혜림(대전대학교); 한재경(대전대학교); 김윤희(대전대학교)" ]	ObjectivesThe purpose of this study is to investigate the clinical characteristics in children and adolescents with peripheralfacial palsy that was treated with Korean medicine. MethodsThe study was conducted based on 284 cases that consisted of 261 children (less than 19 years old) who visitedthe hospital of Korean medicine from August 2010 to August 2014. Then, this study was analyzed by reviewingthe patients’ charts. ResultsThe incidence of facial palsy in pediatric patients was more common in boys than in girls and the mean agewas 11.2 years. The prevalence of facial palsy was more common in winter and most were diagnosed with Bell'spalsy. Recurrence was identified in 12.6% of the patients. The average age of the first attack was 9.5 years. It tookabout 3.2 years for recurrence to occur from the first onset. It took about 5 days to visit the hospital of Koreanmedicine from the onset. 81% of the patients came within 1 week from the onset. 50.7% of the cases did notreceive any treatment before and 49.3% were previously treated at other hospitals. More than half of the patients(65.1%) received Korean medicine first. 54.6% of the patients were hospitalized and 45.4% received outpatienttreatments in the hospital of Korean medicine. Outpatient treatments were administered about 11.5 times whilehospitalized patients were treated for an average of 16.6 days. In general, hospitalized patients were treated moreoften than the outpatient group. An overall average duration of treatment was 70.6 days from the onset of facialpalsy until the last day of treatment, and 53.0 days from the first day of treatment until the last day of treatment. 41.5% of the cases were treated only with Korean medicine and 49.0% were treated with a combination ofKorean and Western medicine. The types of Korean medicine treatment used for facial palsy in descending orderof frequency were acupuncture, Infra red, herbal medicine, SSP therapy, electro-acupuncture, carbone, hot pack,cupping, and moxibustion. The treatments that were most frequently used from Western medicines were steroid asmonotherapy (61.7%) and a combination of steroids and antiviral therapy (37.6%). ConclusionsThis result showed that the risk of facial palsy recurrence among children is relatively high and that facial palsyrequires a long-term treatment. It's helpful to explain about prognosis, treatment duration, and recurrence potentialin children. Facial palsy in children is treated in various ways but more studies about the therapeutic effects ofKorean medicine, Western medicine, and combination of Korean-Western medicine in children are needed.	한의학	null		kci_detailed_000246.xml
ART001932532	oai_dc	Sensitiv ImagoTM 측정에 의한 야뇨증 환아의 검사 결과 보고	The Measurement Results of Nocturnal Enuresis in Children Using Sensitiv ImagoTM	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "최원석(경희대학교 한의과대학); 김덕곤(경희대학교); 이진용(경희대학교)" ]	ObjectivesThe purpose of this study is to report the nocturnal enuresis in children using Sensitiv ImagoTM. MethodsTwenty nocturnal enuresis children were tested using Sensitiv ImagoTM. Results10 cases showed the lowest score at filter #5* and 7 cases showed the lowest score at filter #6* in [ExpressMonitoring] of [Review of System Disorders of Homeostasis]. ConclusionsFurther study with more samples is necessary to establish the accuracy of Sensitiv ImagoTM.	한의학	null		kci_detailed_000246.xml
ART001932531	oai_dc	歸脾溫膽湯加味方의 틱장애 환아 20례에 대한 치료효과	A Case Report of Tic Disorder Children Treated by Kuibiondam-tang Gami	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "강경하(원광대학교 한방소아과); 박은정(원광대학교)" ]	ObjectivesThe purpose of this study is to report 20 cases of tic disorder children who were treated by Kuibiondam-tangGami. MethodsWe treated the tic disorder children with herbal medicine, Kuibiondam-tang Gami. Then we evaluated ticdisorder by Yale Global Tic Severity Scale (YGTSS) and observed the progress of tic disorder. Results20 children (male 17, female 3 / transient tic disorder 6, chronic motor or vocal tic disorder 13, Tourette’sdisorder 1) were studied, the average age of children was 8.45 ± 2.08 years, the average duration of illness was16.55 ± 13.63 month and the mean of treatment was 13.20 ± 9.29 week. After the treatment, mean of YGTSS wasreduced 36.35 ± 9.84 to 9.35 ± 1.03 and total effective rate was 95%. ConclusionsKuibiondam-tang Gami is effective for reducing tic symptom and improving general conditions in children.	한의학	null		kci_detailed_000246.xml
ART001932533	oai_dc	Sensitiv ImagoTM 측정 환아의 BMI에 대한 연구	The Study on Relationships between Body Mass Index and the Measurement Results Using Sensitiv ImagoTM in Pediatric Patients	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "윤상진(경희대학교 한의과대학); 김덕곤(경희대학교); 이진용(경희대학교)" ]	ObjectivesThe purpose of this study is to investigate correlation between body mass index (BMI) and the Sensitiv ImagoTMin pediatric patient. MethodsThe study was conducted with 79 children, who were 5 to 18 years old. They were tested using SensitivImagoTM. Their height, weight were measured for body mass index to find out the relationship between Body MassIndex (BMI) and the result of Sensitiv ImagoTM (SI). Results1. The percentages of the normal weight group (74.68%), overweight group (6.33%), and underweight group(18.99%) were shown respectively. 2. No one was belong to Acute Processes in either groups. 3. In normal weight group, there were Active Processes (16.9%), Unstable Remission (69.5%), Inactive Processes(13.6%), Inactive Process or Development Risk (0.0%). In overweight group, there were Active Processes(20.0%), Unstable Remission (40.0%), Inactive Processes (40.0%), Inactive Process or Development Risk(0.0%). In underweight group, there were Active Processes (6.7%), Unstable Remission (66.7%), InactiveProcesses (20.0%), Inactive Process or Development Risk (6.7%). ConclusionsThere were no significant relationship between Body Mass Index (BMI) and Sensitiv ImagoTM in pediatric patient. Considering that the number of subjects involved in this study was not enough to confirm any results, furtherstudies are necessary to confirm this relationship.	한의학	null		kci_detailed_000247.xml
ART001933217	oai_dc	자폐증 한방 치료에 대한 최신 임상 연구 고찰 - 중의학 논문 중심으로 -	Review of Clinical Studies for Oriental Treatment of Autism in Traditional Chinese Medicine	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이진화(대전대학교 한의과대학 소아과학교실); 한재경(대전대학교 한의과대학); 이혜림(대전대학교 둔산한방병원 한방소아과); 김윤희(대전대학교)" ]	ObjectivesThe purpose of this review is to investigate the clinical studies of oriental treatment for Autism in China andseek the better methods to study and treat Autism in Korea. MethodsWe searched for the study at CNKI by keywords, ‘Autism’, ‘孤独症’, ‘自闭症’, in the last 5years. ResultsSelected 14 clinical studies were divided into 6 case reports and 8 control studies. The subjects of clinical studywere the average 4-9 years old children. It was described that the symptoms were improved after treatment in 6case reports. 8 control studies reported that the experimental group were better effective than the comparison group. Frequently used method for treatment was Scalp acupuncture. ConclusionsIt is promising that we could develop our own treatment and studies for autism in Korea by using Scalpacupuncture, based on these clinical studies.	한의학	null		kci_detailed_000247.xml
ART001932535	oai_dc	대전지역 다문화가정 자녀의 성장에 대한 보고	A Study on the Growth of Multicultural Families' Children in Dae-jeon Area	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이혜림(대전대학교 둔산한방병원 한방소아과)" ]	ObjectivesThe purpose of this study is to evaluate the current growth via Growth indices, Obesity indices, Metabolic riskfactors of Multicultural Families' Children in Dae-jeon area. Methods5 to 12 year old children from 56 multicultural families were enrolled in this study, and were examined theirbone age and body composition, and have received blood tests. Results1. In Growth indices, average height percentile was 53.64 ± 25.59%. The AHP and MPH respectively, wereconverted into 20 years old adult height percentile, AHP of a girls was 40 percentile and MPH was 19percentile, AHP of boys was 57 percentile and MPH was 21 percentile. 2. In Obesity indices, average of BMI pecentile was 44.16 ± 29.52; low-weight group (6 boys, 4 girls),normal-weight group (20 boys, 18 girls), over-weight group (8 girls). Average PWH was 100.51 ± 15.66%;low-weight group (9 boys, 5 girls), normal-weight group (14 boys, 15 girls), over-weight group (3 boys, 5girls), obesity group (5 girls). 3. The results of the relationship between Growth indices and Obesity indices,1) As RH percentile in boys was increased, skeletal maturity, AHP and AHP-MPH were also increased. Similarly, as RH percentile in girls was increased, skeletal maturity, AHP and AHP-MPH were alsoincreased. 2) As skeletal maturity in boys was increased, BMI percentile was also increased. As skeletal maturity in girlswas increased, AHP-MPH was decreased but had no significant differences. ConclusionsCurrent growth of children in multicultural families was above the average when compared to that of averagechildren in the same age. It was predicted that the boys’ height were still above the average adult height, but thegirls’ height were below the average. Also this study showed that girls were more prone to be overweight than boys,thus requiring more intensive management and training in regards to eating habits and exercise.	한의학	null		kci_detailed_000247.xml
ART001932512	oai_dc	환아 보호자 대상으로 실시한 한약 용기 선호도 조사	Preference of Herbal Medicine Packagings for Caregivers	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "정아람(부산대학교 한방소아과); 이혜윤(부산대학교 한방병원); 천진홍(부산대학교); 김기봉(부산대학교)" ]	ObjectivesThe aim of this study is to investigate preferred herbal medicine packaging. MethodsThe study used questionnaires for the caregivers, who have administered their children herbal and westernmedicine. 106 of them were visited the Department of Pediatrics, the Oriental Medicine Hospital of OO University,during the period between in 2014. We used PASW Stastics 18.0 to analyze different dosing methods, and preferred packaging and drugformulations. Results1. 77.4% answered that they use cups to administer medications, 9.4% transferred it to other plastic bottles,8.5% used straw to drink from the pouch, 4.7% drank as it is inside the pouch. Method of taking it wasnot very significant depending on the age. 2. Compare to pills and capsules, 48 responders answered that pills and capsules are easier to take, 11 answeredherbal medication is easier to take. 32 answered that there were no significant difference. 3. 45.3% reported vinyl pouch was preferable, 44.3% answered spout pouch was preferred, 5.7% answered bottlesare convenient, and another 5.7% responders thought cup was fine. Others include syrup bottles had 1 person.These varying preferences were not depending on the age variations. 4. 56.3% answered that price was the main reason why they prefer one over the other. Others 29.2% statedconvenience, 12.5% reported safety, and 10.4% people answered ease of administration as their main reasonfor their preferences. ConclusionsBased on this study, numbers of parents felt inconvenient administering herbal medicine as a vinyl pouch, andfelt necessary to improve this. However, price and other reasons made vinyl pouch still more preferable option. Vinyl pouch that we are using today didn’t show any safety issues. Therefore, it is recommended to still use vinylpouch, but with caps on top to improve administration and distinguishing issues.	한의학	null		kci_detailed_000247.xml
ART001932537	oai_dc	한방산후조리원 산모를 대상으로 실시한 하태독법의 인식 및 의향 조사	A Study Regarding Current Usage of Ha-Taedok Method in Postpartum Mothers	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "정민정(우석대학교)" ]	ObjectivesPurpose of this study is to investigate the current usage of Ha-Taedok Method in postpartum women. Methods36 questionnaires were statistically analyzed by using PASW Statistics 18. ResultsOnly 2 women knew Ha-Taedok Method (5.6%). Women tend not to use Ha-Taedok Method because their children were too young to take herbal medicine(27.8%). However, when being educated about Ha-Taedok Method, they were more likely to take this method thanbefore (13.2%→ 75%). ConclusionsThe utilization of Ha-Taedok Method will improve up on educating post-partum women.	한의학	null		kci_detailed_000247.xml
ART001932519	oai_dc	알레르기성 자반증 환아 치험 2례	A Case Report of Allergic Purpura	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김빛나래(동신대학교 한의과대학); 박젬마(동신대학교 한의과대학 소아과학교실); 채중원(동신대학교)" ]	ObjectivesThe purpose of this study is to report the clinical effects of Korean herbal medicine and Chimsband treatmentin patients with allergic purpura. Methods4-year-old female patients, who were suffering from allergic purpura were treated by Korean herbal medicine(Samul-tang hap Yukmijihwang-tang gami) and Chimsband treatment. Also, photographs were used to check theimprovement. ResultsAfter treating for 15 days, the patients' allergic purpura were improved by Korean herbal medicine andChimsband treatment. ConclusionsThis study showed that Korean medical treatments could be an effective treatment option in treating allergicpurpura.	한의학	null		kci_detailed_000247.xml
ART001932491	oai_dc	한방병원 응급실에 내원한 소아 환자에 관한 임상적 고찰	A Clinical Study of the Pediatric Patients Who Had Visited the Emergency Room (ER) at the Oriental Medical Hospital	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김지은(대구한의대학교 한의과대학); 백정한(대구한의대학교)" ]	ObjectivesBy analyzing data of the pediatric patients who had visited the emergency room of the oriental medical hospital,we can understand their characteristics and diseases. The purpose of this study was to introduce the excellence ofthe Oriental medicine, to develop various treatments, and to revitalize pediatric emergency care at the orientalmedical hospital. MethodsThe study was composed of 334 pediatric patients who had visited the emergency room of the ○○ universityoriental hospital from January 2011 to December 2013. Results1. It has showed that between 7 to 12 years old patients (27.8%) were the most common age populations. 2. The number of pediatric patients was increased during February. According to the weekly distribution data,the number of pediatric patients who had visited on Sunday was the highest (28.7%). Also, the number ofpediatric patients who had visited the ER between 21 to 24 hours (29.0%) was the highest. 3. The two major reasons for inpatient hospitalization were digestive and nerve-related symptoms. Nerve-relatedsymptoms were the most common in infants while digestive symptoms were the most common in other childdevelopment stages. 4. The duration of time interval from the onset of symptoms to the ER visit was most commonly within 6 hours(50.3%). An acupuncture and herbal medication treatment (70.1%) were the most common medicaltreatments. The majority of the pediatric patients (95.5%) were discharged after their medical treatments. ConclusionsA serious acute illness was not the most common reason for the ER visit among the pediatric patients. The mostcommon disease states that have preferred to be treated with the oriental medicine were dyspepsia, crying, facialpalsy, and ankle sprain. We have to introduce the excellence of the oriental medicine. We also need to trydeveloping other treatments such as magnetic acupuncture, aromatherapy, and revitalizing pediatric emergency careat the oriental medical hospital.	한의학	null		kci_detailed_000247.xml
ART001932505	oai_dc	성조숙증으로 진단된 여자 환아에서 호르몬 수치가 개선된 치험 1례	A Case Report of Precocious Puberty in a Female Patient : Significant Improvement in Controlling the Sex Hormone Levels	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "임영권(아이조아 한의원 수원점); 허광욱(아이조아 한의원 수원점); 박송이(아이조아한의원 수원점); 서경석(아이조아 한의원 평택점); 천상렬(아이조아 한의원 부산점); 이석진(아이조아 한의원 성북점); 이훈(경희맑은사람 한의원); 김호철(경희대학교)" ]	ObjectivesThe purpose of this study is to find out how taking oriental herbal medicine may affect the sex hormone levelsin a patient who was diagnosed with prematurity. MethodsWe prescribed 120 cc of oriental herbal medicine twice daily for a month to a patient suspected of the precociouspuberty due to 11 pg/ml of the estradiol level. Upon finishing the course of oriental herbal medicine, the patientwas retested for the follicular stimulating hormone, luteinizng hormone and estradiol levels. ResultsAfter administration, all levels of luteininzing hormone, follicular stimulating hormone and estradiol weredecreased. There was no diagnosable evidence for the idiopathic central precocious puberty in the gonadotropinreleasing hormone stimulation. ConclusionsOriental herbal medicine is a good alternative treatment of choice for the precocious puberty. However, morein-depth studies are to be followed.	한의학	null		kci_detailed_000247.xml
ART001879069	oai_dc	C57BL/6N 마우스 탈모모델에서 미세다륜침과 영지추출물이 모발성장에 미치는 영향	Effects of Ganoderma Lucidum Extract Ethanol Extract and Microneedle Therapy System on Hair Growth in an Alopecia Model of C57BL/6N Mice	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "주봉현(동의대학교); 유선애(동의대학교); 강경화(동의대학교); 이승연(동의대학교)" ]	ObjectivesThis study was carried out to investigate the effect of Ganoderma lucidum extract (GLE) and microneedletherapy system (MTS) on hair growth in an alopecia model of C57BL/6N mice. MethodsFive-week old mice were depilated and separated in 4 groups ; CON (50% EtOH), MXD (5% Minoxidil), MTSand GLE + MTS. The treatments were applied twice a week for 3 weeks. The hair growth was determinedphotographically, the hair density, thickness and length were identified by Folliscope and the weights of body andorgans were measured. In dorsal skin tissue, the expression of hair growth-related gene and protein was analyzedby RT - PCR or Western blot. In addition, the hair follicles in the dermis were observed by H&E staining. ResultsThe promotion of hair growth was observed in GLE + MTS and MTS compared to CON. The hair density,thickness and length were also improved in GLE + MTS and MTS compared to CON. The mRNA expression ofTGF-α, TGF-β1, IGF-1, PRL and PL and the protein expression of VEGF and IGF-1 were increased in GLE + MTSand MTS compared to CON. The hair follicles and hair root growth were improved in GLE + MTS and MTScompared to CON. In the above results, GLE + MTS were more effective than MTS. ConclusionsThese results suggest that GLE and MTS has a hair growth activity and can be useful for the treatment ofalopecia.	한의학	null		kci_detailed_000247.xml
ART001879071	oai_dc	소아 전문 한의사를 대상으로 실시한 하태독법의 인식 및 사용실태 조사	A Study Regarding Current Usage of Ha-Taedok Method in Korean Pediatrician	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "정민정(우석대학교)" ]	ObjectivesThis study is to know the current usage of Ha-Taedok Method in Korean pediatrician. Methods69 questionnaires were statistically analyzed by using PASW Statistics 18. Results55 Korean Medicine doctors knew Ha-Taedok Method, but only 2 doctors were using Ha-Taedok Method intheir practice. The doctors tend not to use Ha-Taedok Method because it was hard to get permission from thepatient’s caregiver. 11 Korean Medicine doctors used Ha-Taedok Method to their own children though. Thepediatricians felt satisfied from the effect of Ha-Taedok Method especially because it can prevent from disease. Theyreported no side effect and adverse effect. Coptidis Rhizoma is a preferred herb to use along with Ha-TaedokMethod. For a better result from Ha-Taedok Method, it is recommended to start within 3 days old of patient. ConclusionsHa-Taedok Method may be effective as preventive method.	한의학	null		kci_detailed_000247.xml
ART001878981	oai_dc	MC/9 비만세포에서 杏仁 추출물의 Th2 cytokine 발현 억제 효과 및 신호전달 기전 연구	The Suppressive Effect on Th2 Cytokines Expression and the Signal Transduction Mechanism in MC/9 Mast Cells by PRAL	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "강기연(대전대학교 한의과대학 소아과학교실); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]	ObjectivesPRAL (Prunus armniaca Linne Var) is a herbal formula in Oriental Medicine, known for its anti-inflammatoryand anti-allergenic properties. However, its mechanism of action and the cellular targets have not yet been found enough. The purpose of this study is to investigate the effects of PRAL on Th2 cytokines expression in MC/9 mast cells. MethodsThe effect of PRAL was analyzed by ELISA, Real-time PCR, Western blot in MC/9 mast cells. mRNA levels ofGM-CSF, IL-4, IL-5, IL-6, IL-13, TNF-α were analyzed with Real-time PCR. Levels of IL-13, MIP-1α were measuredusing enzyme-linked immunosorbent assays (ELISA). NFAT, AP-1 and NF-κB p65 were examined by Western blot analysis. ResultsPRAL inhibited GM-CSF, IL-4, IL-5, IL-6, IL-13, TNF-α mRNA expression in a dose dependent manner. GM-CSF,IL-4, IL-5 mRNA expression were inhibited significantly in comparison to DNP-IgE control group at concentrationof 100 ㎍/㎖ and IL-6, IL-13, TNF-α mRNA expression were inhibited at concentration of 50 ㎍/㎖, 100 ㎍/㎖. PRAL also inhibited the IL-13, MIP-1α production significantly in comparison to DNP-IgE control group in adose dependent manner. IL-13 production was inhibited at a concentration of 200 ㎍/㎖, 400 ㎍/㎖ and MIP-1αwas inhibited at a concentration of 100 ㎍/㎖, 200 ㎍/㎖, 400 ㎍/㎖. Western blot analysis of transcription factors involving Th2 cytokines expression revealed prominent decrease of themast cell specific transcription factors including NFAT-1, c-Jun as well as NF-κB p65 but not NFAT-2 and c-Fos. ConclusionThese results indicate that PRAL has the effect of suppressing Th2 cytokines production in the MC/9 mast cells. These data represent that PRAL potentiates therapeutic activities to the allergic disease by regulating Th2 cytokinesin the MC/9 mast cells.	한의학	null		kci_detailed_000247.xml
ART001878979	oai_dc	허약아와 성장지표의 상관성에 대한 연구	A Study on Comparison between Growth Indices of Weak Children Groups via Analyzing Bone Age and Body Composition	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "이혜림(대전대학교 둔산한방병원 한방소아과); 한재경(대전대학교 한의과대학); 김윤희(대전대학교)" ]	ObjectivesThe purpose of this study is to investigate the relationship between weak children and growth indices. MethodsOne hundred twenty-six of the first and the second grade elementary school students who didn't have to developyet their secondary sexual characteristics answered the questionnaire. Their bone age and body composition were measured. Results1. According to the Weak Children questionnaire analysis, respiratory problem was one of the biggest problemsin the weak children group (35.7%), followed by digestive problems (23.0%), psycho-neurological problems(22.2%), neuromotor problems (9.5%), and urogenital problems (8.7%). 2. From the comparison between growth indices of weak children and that of normal children are as follows:1) The group of children who had problem in their digestive system had lower growth indices than the normalaverage children group. The growth indices includes mean height, weight, total body water, protein mass, mineralmass, body fat, skeletal muscle mass, body fat percentage, body mass index (BMI), and basal metabolic rate (BMR). 2) The children who had urogenital weakness had lower mean height, RH (Recent Height), RH - MPH {RecentHeight(%) - Mid-Parental Height(%)}, RUS (Radius, Ulna and Short bone) score, weight, protein mass, bodyfat, BMI, and visceral fat than the normal children group. 3. The results of the multiple comparisons of growth indices and weak children groups are as follows:1) Digestive weak children were the lowest in total body water, protein mass, mineral mass, skeletal musclemass, and basal metabolic rate. 2) Urogenital weak children were the lowest in height, RH, RH - MPH, RUS score, and weight. ConclusionThese results showed that children’s growth is strongly correlated to their own growth problems, especially tothose children who have digestive and urogenital problems. Therefore, this may be an effective way for childrengrowth treatment in Korean medicine to treat weak symptoms.	한의학	null		kci_detailed_000247.xml
ART001879068	oai_dc	필용방감길탕이 기도 뮤신의 분비, 생성, 유전자 발현 및 점액 과다 분비에 미치는 영향	Effect of Piryongbanggamgil-tang on Airway Mucin Secretion, Production, Gene Expression and Hypersecretion of Mucus	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "김윤영(동국대학교 한의과대학); 민상연(동국대학교); 김장현(동국대학교)" ]	ObjectivesIn this study, the author tried to investigate whether piryongbang-gamgil-tang (PGGT) significantly affect in vitroairway mucin secretion, PMA- or EGF- or TNF-α-induced MUC5AC mucin production / gene expression from humanairway epithelial cells and increase in airway epithelial mucosubstances and hyperplasia of tracheal goblet cells of rats. Materials and MethodsFor in vitro experiment, confluent RTSE cells were chased for 30 min in the presence of PGGT to assess the effectof PGGT on mucin secretion by enzyme-linked immunosorbent assay (ELISA). Also, effect of PGGT on PMA- or EGForTNF-α-induced MUC5AC mucin production and gene expression from human airway epithelial cells (NCI-H292) wereinvestigated. Confluent NCI-H292 cells were pretreated for 30 min in the presence of PGGT and treated with PMA(10 ng/ml) or EGF (25 ng/ml) or TNF-α (0.2 nM) for 24 hrs, to assess both effect of PGGT on PMA- or EGF- or TNF-α-inducedMUC5AC mucin production by ELISA and gene expression by reverse transcription-polymerase chain reaction (RT-PCR). For in vivo experiment, the author induced hypersecretion of airway mucus and goblet cell hyperplasia by exposureof rats to SO2 during 3 weeks. Effect of orally-administered PGGT during 2 weeks on increase in airway epithelialmucosubstances from tracheal goblet cells of rats and hyperplasia of goblet cells were assesed by using histopathologicalanalysis after staining the epithelial tissue with alcian blue. Possible cytotoxicities of PGGT in vitro were assessed by examining LDH release from RTSE cells and the rateof survival and proliferation of NCI-H292 cells. In vivo liver and kidney toxicities of PGGT were evaluated by measuringserum GOT/GPT activities and serum BUN/creatinine concentrations of rats after administering PGGT orally. Results(1) PGGT did not affect in vitro mucin secretion from cultured RTSE cells. (2) PGGT significantly inhibitedPMA-, EGF-, and TNF-α-induced MUC5AC mucin productions and the expression levels of MUC5AC mRNA fromNCI-H292 cells. (3) PGGT decreased the amount of intraepithelial mucosubstances and showed the tendency ofexpectorating airway mucus already produced. (4) PGGT increased LDH release from RTSE cells. However, PGGTdid not show in vivo liver and kidney toxicities and cytotoxicity to NCI-H292 cells. ConclusionThe result from this study suggests that PGGT can regulate the production and gene expression of airway mucinobserved in diverse respiratory diseases accompanied by mucus hypersecretion and do not show in vivo toxicity toliver and kidney functions after oral administration. Effect of PGGT with their components should be further studiedusing animal experimental models that reflect the diverse pathophysiology of respiratory diseases through future investigations.	한의학	null		kci_detailed_000247.xml
ART001879067	oai_dc	캠프 형식의 입원 치료를 받은 소아 아토피피부염 환자 6례	6 Cases of Atopic Dermatitis Children Patients for Hospitalization Program	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "신미란(세명대학교); 오진아(세명대학교충주한방병원 사상체질과); 이동녕(세명대학교)" ]	ObjectivesThis study investigated the effect of camping style Hospitalization program for atopic dermatitis childrenpatients. Methods6 patients were admitted for camping style hospitalization program. The program includes acupuncture, herbalmedicine, examination, education, psychotherapy, dressing, exercise. The patients were analyzed by Severity ScoringAtopic Dermatitis (SCORAD) index and measured skin pH value (pH). Also, patients evaluated themselves bywriting an atopic dermatitis diary which consists of diet, emotion, severity of pruritus, and sleep loss. Checkedquestionnaires which consists of atopic dermatitis, self treatment methods and each program satisfaction. ResultsAfter 7 days of hospitalization program, the patient’s SCORAD index scores were decreased and most of thepatient’s symptoms were improved. ConclusionsThe hospitalization program could be helpful for atopic dermatitis children patients.	한의학	null		kci_detailed_000247.xml
ART001854706	oai_dc	아토피 안심마을로 이주한 아토피 환아의 관찰연구	A Observational Study on Children with Atopic Dermatitis in Atopic-Free Village	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "성현경(대전대학교); 서경숙(대전대학교); 손창규(대전대학교)" ]	ObjectivesThis study aimed to evaluate the effects of atopic care program through observing atopic patients who have livedin atopic-free village located Geumsan of Chungnam province. MethodsSeventeen children (boy 7, and girl 10) with atopic dermatitis had moved into atopic-free village of Geumsan,and they have been cared with atopic care program. Atopic dermatitis symptoms were measured every month usingSCORAD (Scoring of Atopic Dermatitis) and EASI (Eczema Area and Severity Index) from March, 2012 toSeptember, 2013. The changes of scores were analyzed using paired t-test. ResultsThe median month of residence period was 19.9 months (range from 6 to 42 months). The atopic symptomswere significantly improved on SCORAD (p<0.01) and EASI (p<0.1) respectively. ConclusionDespite the limitation of the small number of study subjects, this study may provide the possibility of naturalenvironment-based therapy for children with atopic dermatitis.	한의학	null		kci_detailed_000247.xml
ART001854707	oai_dc	식욕부진을 주소로 내원한 환아의 현황 및 보호자 인식도 조사	A Survey of the Growth State of the Children with Anorexia and the Perception of Their Parents	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "유선애(동의대학교); 이승연(동의대학교)" ]	ObjectivesMany parents are stressed from their children with anorexia, so this study was planned to investigate the growth state of the children with anorexia and the main concerns of their parents. MethodsWe searched some medical documents regarding 21 children with anorexia and performed questionnaires on their parents. Results21 children (male 14, female 7) were studied, the average age of children was 53.62±20.46 months, the average height was 102.93±12.36㎝, the average weight was 16.37±1.31㎏, the average BMI was 15.26±1.31. 16 (76.10%) parents have experienced stress regarding their children's slow weight increase. There was no relationship between BMI of the children and the degree of stress of their parents. The parents tend to scold or to give nutrition supplement to their children to solve the anorexia. Many of the parents considered their children has anorexia just by looking at the children's attitude towards to the meals or when children had food whatever it given only. ConclusionsThe children with anorexia were mostly developed poorly. However, the parents who had children were developing nicely were also stressed because of their children's picky eating behavior and the difficults in coaching their children food.	한의학	null		kci_detailed_000247.xml
ART001854710	oai_dc	분만손상으로 인한 상완신경총마비 환아의 치험 1례	A Case Report of Child with Brachial Plexus Palsy Due to Birth Injury	{ "journal_name": "대한한방소아과학회", "publisher": null, "pub_year": null, "pub_month": null, "volume": null, "issue": null }	[ "유선애(동의대학교)" ]	ObjectivesThe purpose of this study is to know the effect of acupuncture on brachial plexus palsy due to birth injury. MethodsWe decided to treat one week of Vojta therapy and occupational therapy, but other were combined, and thenadd three weeks of acupuncture treatment as well. ResultsRight clavicle fracture at birth brachial plexus injury due to decreased locomotion of the right upper extremity,muscle weakness in children aged 7 months to Vojta therapy, occupational therapy and acupuncture, whenperformed in conjunction mobility increase of the shoulder joint, elbow support improvement, recovery of motorfunction of the hand grip, etc. to obtain a significant motor function recovery improvement. ConclusionAcupuncture was a good treatment of choice for the better shoulder, joint and hands movements.	한의학	null		kci_detailed_000247.xml

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