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|---|---|---|---|---|---|---|---|---|---|---|---|---|
ART001052098 | oai_dc | 加味淸心蓮子湯이 NC/Nga mice의 아토피樣 피부염에 미치는 영향 | Effect of Kami-chungsimyeunjatang on atopic dermatitis-like skin lesions induced in NC/Nga mice by mite antigen stimulation | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김윤희(대전대학교); 윤지연(대전대학교); 한재경(대전대학교)"
] | 한의학 | null | kci_detailed_000250.xml | ||||
ART001052094 | oai_dc | 최근 임상연구를 중심으로 한 소아비만에 관한 방법론적 연구 | Methodological research of obese children focused on the recent clinical researches | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김장현(동국대학교); 이현숙(동국대학교)"
] | Methodological research of obese children focused on the recent clinical researches
Lee Hyun Sook, Kim Jang Hyun
Department of Pediatrics, College of Oriental Medicine, Dongguk University
Objectives : The purpose of this study is to investigate the recent tendency of clinical researches of obese children for finding better oriental medicine treatments.
Methods : This study was focused on diagnoses, treatments, prognoses and cures of obese children based on 37 of other papers which are J Korean Oriental Med, J Korean Oriental Pediatrics, J Korean Acd Fam Med, J Korean society for the study of obesity, Korea Sport Research, J Korean Academy of Pediatric Allergy and Respiratory Disease, J Korean Society for Health Education and Promotion, Korean J Pediatric, and Korean J Oriental Physiology and Pathology.
Results : The rate of obese children has been increased continuously. There are several reasons for increased rate : For example, inadequate eating habit, lack of exercise, and genetic factors such as inherited diseases, and the disorder of the endocrine system. The obesity in childhood or adolescent can cause not only the physical problems but also the mental problems. It is necessary for children to diet, change life style, exercise continuously, and being active in order to prevent child obesity and keep healthy. Obesity can be treated through therapy diet, exercise, behavior modification, drug therapy and operation.
Conclusion : It is important to recognize the children obesity, and make better treatments for that in the way of oriental cure. Moreover, additional reports should be keeping up based on continuing clinical researches. | 한의학 | null | kci_detailed_000250.xml | |||
ART001052104 | oai_dc | 防風通聖散加味方이 肥滿誘導 白鼠에 미치는 影響 | Effects of Bangpoongtongsungsankamibang extract on the obese SD rats induced by 2% cholesterol diet | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김덕곤(경희대학교); 김병우(경희대학교)"
] | Effects of Bangpoongtongsungsankamibang extract on the obese SD rats induced by 2% cholesterol diet
Kim Byung Woo, Kim Deog Gon
Department of Pediatrics, college of Oriental Medicine, Kyunghee University
Objectives : These experimental studies were designed to investigate the effects of Bangpoongtongsungsankamibang on the weight and the lipid metabolism of the obese rats induced by 2% cholesterol diet. They were designed to change values in the serum and leptin levels in the rats.
Materials and Methods : The serum and leptin levels were measured for a period of 8 weeks for obese SD rats induced by 2% cholesterol diet.
Results : The body weight showed a tendency to decreased significantly in sample (p<0.05). The Total cholesterol and Triglyceride level significantly decreased in sample (p<0.05). The HDL Cholesterol levels significantly increased in sample (p<0.05). The LDH levels did not show a significant change in sample. The ALP levels significantly decreased in sample (p<0.05). The SGOT and SGPT level did not show a significant change in sample. The Leptin levels significantly decreased in sample (p<0.05). The average size of the epididymal fat cell significantly decreased in sample (p<0.05). | 한의학 | null | kci_detailed_000250.xml | |||
ART001052097 | oai_dc | 『及幼方』에 기재된 醫案에 대한 硏究 | A study on the Medical records in the Gupyubang | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"장규태(경희대학교); 한윤정(경희대학교)"
] | A study on the Medical records in the Gupyubang
Han Yun Jeong, Chang Gyu Tae
Department of Pediatrics, College of Oriental Medicine, Kyunghee University
Objectives : The Medical Records(醫案) are important materials in studying the developmental process of Korean Traditional Medicine. The purpose of this study was to investigate the medical records which were described in Gupyubang(及幼方), the first Korean book that specialized in pediatrics.
Methods : 85 Medical records about medical traits of diagnosis and treatments in Gupyubang were analyzed and those were translated in Korean.
Results : Medical records were analyzed as follows; The number of Male was 76 and the number of Female was 9. Prepubertal period was 16 and preschool period 14. Acute febrile convulsion was 6. Measles and blood symptom was 5. Ring worm pain, vomiting & diarrhea, colic pain was 4. Most of them were self treatment except one. 77 cases were improved and 6 cases were dead or worse. The medical records used oral medication, external medication, acupuncture, moxibustion and surgical manners.
Conclusion : This study showed that Gupyubang is a experiential book and alse the medical records in Gupyubang was usefulness and had practical value. | 한의학 | null | kci_detailed_000250.xml | |||
ART001052095 | oai_dc | 여드름에 대한 文獻的 考察 -最近 中醫 雜誌를 中心으로- | A literature study on acne in Traditional Chinese medical journals | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김장현(동국대학교); 정우병(동국대학교)"
] | A literature study on acne in Traditional Chinese medical journals
Jung Wu Byung, Kim Jang Hyun
Department of Pediatrics, College of Oriental Medicine, Dongguk University
Objectives : The purpose of this study is to make the oriental medical treatment useful, and to develop the ways of acne cure.
Methods : Recent paper about Traditional Chinese medicine of acne was analyzed for this studying.
Results : According to the latest researches of Acne treatment with Chinese medicine, oriental medical methods to chronic acne were effective.
Conclusions : Oriental medical treatment can be classified into 3 parts; internal cure, external cure, and acupuncture therapy. All of these ways were efficacious to cure chronic Acne. | 한의학 | null | kci_detailed_000250.xml | |||
ART001180375 | oai_dc | Clinical Assessment of Efficacy, Safety and Usefulness of Traditional Herbal Medicine (THM) on Atopic Dermatitis | Clinical Assessment of Efficacy, Safety and Usefulness of Traditional Herbal Medicine (THM) on Atopic Dermatitis | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이진용(경희대학교); 김덕곤(경희대학교); 고덕재(경희대학교); 유한정(경희대학교)"
] | 아토피 피부염에 대한 한약치료의 효과, 안전성 및 유용성에 대한 임상 평가
고덕재, 유한정, 이진용, 김덕곤
경희대학교 한의과대학 소아과학 교실
목적 : 본 연구를 통하여 아토피 피부염 환아의 한약치료 후 임상 효능, 안전성 을 평가하고, 나아가 효능과 안전성을 종합적으로 평가함으로써 아토피 피부염에 대한 한약치료의 유용성을 평가하고자 한다.
방법 : 경희대학교 한의과대학 부속한방병원 한방소아과에 내원한 아토피 피부염 환아 39명의 한약치료 전후의 의무기록을 검토하였다. 아토피피부염 치료에 대한 한약의 효능을 평가하기 위하여 치료 후 아토피 피부염의 개선 정도에 대한 부모의 평가를 VAS를 사용하여 분석하였다. 아토피 피부염에 대한 한약치료 후 안정성의 평가를 위하여 치료 전후 혈중 AST, ALT, BUN, creatinine 변화를 검토하여 한약치료의 간신독성 여부에 대해 조사하였고, 보호자에 대한 설문조사를 통하여 한약치료 후 발생한 부작용 및 불편한 증상의 종류 및 정도를 평가하였다. 나아가 한약의 효능 및 안정성을 종합적으로 평가하여 아토피 피부염에 대한 한약 치료의 유용성을 분석하였다.
결과 및 결론 : 환아 39명 중 27명 (69%) 의 부모가 한약치료가 아토피 피부염의 개선에 효과가 있다고 보고하였다. 안정성의 평가에 있어서, 39명의 환자에게서 한약 치료 후 간장과 신장에 미치는 독성이 발견되지 않았다. 2명의 환아가 일시적이고 경미한 복부 불쾌감을 호소하였으나, 한약투여와의 관련성은 관찰되지 않았다. 1명의 환아에서 경미한 복통이 발견되었으나, 의학적 치료 없이 증상은 소실되었으며, 치료 과정의 중단 없이 계획되었던 모든 치료 과정을 종료하였다. 치료 후 상기 환아는 아토피 피부염의 증상 개선 뿐 아니라 변비증상의 완화, 만성적 어지러움의 개선 등 제반 신체 조건의 호전을 보고 하였다. 임상적 효능과 안전성을 종합적으로 고려할 때, 환아 39명 중 27명 (69%) 의 사례에서 한약치료가 아토피 피부염의 유용한 치료수단으로 평가되었다. 이를 근거로 한약 치료가 아토피 피부염에 대하여 안전성을 가진 유용한 치료방법이라 사료되며, 향후 임상적 효능과 안전성을 객관적으로 평가할 수 있는 대규모의 임상연구가 필요하리라 사료된다. | 한의학 | null | kci_detailed_000250.xml | |||
ART001180420 | oai_dc | 3T3-L1 cell에서 방풍통성산의 지방세포 분화 억제 효과 연구 | Effects of Bangpoongtongsungsan on adipose tissue and hyperlipidemia of 3T3-L1 induced Rats | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김덕곤(경희대학교); 이진용(경희대학교); 이경태(경희대학교); 차민경(경희대학교)"
] | 한의학 | null | kci_detailed_000250.xml | ||||
ART001181063 | oai_dc | 영兒 脂漏性 皮膚炎에 대한 證例 1例 | A case report of Seborrheic Dermatitis in an infant | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김장현(동국대학교); 김기봉(부산대학교)"
] | A Case Report of Seborrheic Dermatitis in an Infant
Kim Ki Bong, Kim Jang Hyun
Department of Pediatrics, College of Oriental Medicine, Dongguk University
Objectives:The objective of this study is to assess the clinical effect of illinition and carbon-ray treatment on seborrheic dermatitis.
Methods:This clinical study was carried out with one case(male) who visited the Department of Pediatrics, Dongguk University Bundang Oriental Hospital and it was diagnosed as seborrheic dermatitis. It is treated with illinition for 37 days and carbon-ray treatment in 12 times. We checked the aspect of wound.
Results:The child`s wound improved, and the seborrheic dermatitis disappeared.
Conclusions:Illinition and carbon-ray treatment are effective in the treatment of seborrheic dermatitis and improve the function of removing inflammation and regerenating the skin in the body.
Key words:seborrheic dermatitis, illinition, carbon-ray treatment | 한의학 | null | kci_detailed_000250.xml | |||
ART001181110 | oai_dc | 주의력결핍과잉행동장애 치료에 대한 문헌적 고찰 : 최근 중의잡지를 중심으로 | The Literature Study for Attention Deficit Hyperactivity Disorder(ADHD) in Traditional Chinese Medical Journals | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김장현(동국대학교); 김희은(동국대)"
] | The Literature Study for Attention Deficit Hyperactivity Disorder(ADHD) in Traditional Chinese Medical Journals
Kim Hee Eun, Kim Jang Hyun
Department of pediatrics, College of Oriental Medicine, Dongguk University
Objective : The aim of this study was to investigate treatment of Attention Deficit Hyperactivity Disorder(ADHD) in current Traditional Chinese Medical Journals.
Methods : From January 2000 to December 2005, we searched Traditional Chinese Medical Journals.
Results : 21 articles were selected and classified into two large groups, case report and comparison study. Totally 1137 cases, complete cures are 276, significant improvements and some improvement 1028, complete cure rate 24.27%, total improvement rate 90.41%.
Conclusion : Oriental medical treatments for ADHD were investigated to be effective in most trials. But there remains a debate about outcome criteria. Further studies are needed. Treatment methods were herbal medicine, acupuncture, auricular acupuncture, family consult.
Key words : Attention Deficit Hyperactivity Disorder, ADHD, Traditional Chinese Medical Journals. | 한의학 | null | kci_detailed_000250.xml | |||
ART001180376 | oai_dc | 기歸補腎湯 투여가 야뇨증 환아에 미치는 영향에 관한 임상적 연구 | The clinical effect of Gikwuibosin-tang on nocturnal enuresis | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이승연(동의대학교); 주봉현(동의대); 장지혜(동의대); 정민정(동의대)"
] | The Clinical Effect of Gikwuibosin-tang on Nocturnal Enuresis
Ju Bong Hyun, Jang Ji Hye, Jeong Min Jeong, Lee Seung Yeon*
Department of Pediatrics, College of Oriental Medicine, Dong-Eui University
*Department of Pediatrics, College of Oriental Medicine, Dong-Eui University Clinical Research Center of Oriental Medicine, Dong-Eui University
Objective : The objective of this study is to assess the clinical effect of Gikwuibosin-tang on nocturnal enuretic children.
Methods : This clinical study was carried out with 15 cases of children aged 5 to 10 years old who visited the 00 Oriental Clinic between February 2005 and August 2005 and who were diagnosed as the nocturnal enuresis.
The data of present symptom and improvement progress was collected via telephone interviews with their mother.
Results : The total number of children was 15, 10 of them were male and 5 were female. Sex ratio was 2:1. Patients under 6 years old were 9(60%). After the treatment of oriental medicine after 2～3months, 6 of the children were improved completely and 7 of them were cured quite well, 2 of them were recovered in a half way. the treatment performed very well so there's no case which were not improved at all. And a ratio of the perfect cure was 40%. Following-up survey by telephone, the treatment were performed completely for 8 of them and 4 of them were almost improved but 3 of them were not improved. And a ratio of the perfect cure was 53.3%.
Conclusion : Gikwuibosin-tang is effective in the treatment of nocturnal enuretic children. Further study is needed with more cases.
Key words : Gikwuibosin-tang, nocturnal enuretic children. | 한의학 | null | kci_detailed_000250.xml | |||
ART000974303 | oai_dc | 소아의 한약복용과 비만에 대한 후향적 연구 | A Retrospective Study on Herbal Medication and Obesity for Children | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"강현경(세종대학교); 이승연(동의대학교); 장지혜(동의대)"
] | A Retrospective Study on Herbal Medication and Obesity for Children
Jang Ji Hye, Kang Hyun Kyoung, Lee Seung Yeon*
Department of Pediatrics, College of Oriental Medicine, Dongeui University
*Department of Pediatrics, College of Oriental Medicine, Dongeui University,
Clinical Research Center of Oriental Medicine, Dongeui University
Objective : As today obese children have increased rapidly in Korea, the interest has been much increased. And parents concern about the effect of Herbal Medication(HM) on gaining weight. Therefore we had a retrospective study HM and obesity for children.
Method : We examined medical record of 38 patients who visited to Department of Pediatrics in 00 medical center from 2002 to 2006 and took HM. Their Hight, Weight, Obesity Index(OI) were estimated at two points: before and after HM treatment. And they were divided into two groups according to the HM type and analyzed for differences of OI.
Result : There were no significant changes in 38 patients's OI before and after treatment. But only one case gained over weight(OI: 21.31). OI increased slightly after treatment but there were not statistically significance. OI according to the HM type had slightly difference but there were not statistically significance. There were no connections between HM type, the number of days taking HM and changes of OI.
Conclusion : On the basis of this study, we thought there were no connections between HM and obesity for children. But this study's cases are small in number so more study is need.
Key words : Herbal Medication(HM), Obesity Index(OI) | 한의학 | null | kci_detailed_000250.xml | |||
ART001181112 | oai_dc | 천안지역 초등학생의 2차 성징 발현 시기에 대한 연구 | A study of manifestation period of sex character among elementary student in Cheon-an | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김윤희(대전대학교); 이남열(대전대); 한재경(대전대)"
] | A Study of Manifestation Period of Sex Character Among Elementary Student in Cheon-an
Lee Nam Yeol, Han Jae Kyung, Kim Yun Hee
Department of Pediatrics, College of Oriental Medicine, Daejeon University
Objective:In order to educate juveniles with proper sex education and to present advisable sexual culture among them, we researched the revelation age and duration period of secondary sex characteristics of 5th and 6th elementary student in Cheon-an, and compared them with their mother's case.
Method:We did a survey among 5th and 6th grade elementary student in Cheon-an, which includes pictures presenting different stages of breasts and pubic hair development.
Results:Results show that in girls, average menarche age was 11.47 while the average of their mother's was 14.25. 3 years of decline was observed. On boys, average pubic hair development age was 11.42, similar to the average age of voice change, 11.43. Girls showed relatively earlier distribution of pubic hair manifestation age of 11.39, than in boys, which was 11.42. Concerning the sexual maturity, 99% of girls were over B2, while 43% of boys were over PH2. Almost all of the female participants manifested secondary sex characteristics, and half of them were in the stage of pubic hair development.
Conclusion:We observed that the average age of manifesting secondary sex characteristic among elementary students is getting younger and especially, menarche age of young girls is significantly showing downward tendency compared to their mothers'. Sex education in elementary schools should be carried out considering the development stage of secondary sex characteristics among students.
Key words:Secondary sex character, Sexual maturity, Menarche age, Sex education | 한의학 | null | kci_detailed_000250.xml | |||
ART001181064 | oai_dc | 調元散加味方이 흰쥐의 成長에 미치는 影響 | The effect of Jowonsangamibang on the growth of the rats. | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"백정한(대구한의대학교); 김봉성(대구한의대); 서정민(대구한의대)"
] | Effect of Jowonsangamibang on the Growth of the Rats
Kim Bong Sung, Seo Jung Min, Baek Jung Han
Department of pediatrics, College of Oriental Medicine, Daegu Haany University
Objective : The purpose of this study is to find out the effect of Jowonsangamibang(JWS) on the growth of rats.
Methods : First of all, we divided male Sprague-Dawley rats into 4 groups(J1, J2, J3 and sham group). Then J1, J2 and J3 groups were administered with JWS water extracts(JWSE) once a day at a dosage 250, 500, 1,000㎎/㎏ respectively for 3 weeks. The sham group was administered with normal saline in the same manner. And we measured body weight, amount of body weight increased, length of femur, serum GH, serum IGF-Ⅰ, serum TSH and serum testosterone after each week.
Results : There were no significant changes of body weight, the level of GH, TSH, and testosterone in J1, J2 and J3 groups. The change of body weight gained was increased significantly in the J3 group compared with the sham group after 1, 2 and 3 weeks. The length of the femur was increased significantly in the J2 group after 1 week and in the J3 group after 3 weeks compared with the sham group. The level of IGF-Ⅰ in the serum was increased significantly in J1, J3 after 1 week compared with the sham group.
Conclusion : According to the results above, JWS increased body weight, length of femur, serum GH, serum IGF-1 compared with the sham group. This study shows that JWS has an effect on promoting the growth of rats, thus it's expected to treat of growth delay in children.
Key words : Jowonsangamibang(JWS), growth, body weight, length of the femur, GH, IGF-Ⅰ, TSH | 한의학 | null | kci_detailed_000250.xml | |||
ART000974305 | oai_dc | 놀이치료를 병행한 틱장애 환아 치험 1례 | A Case Study on Tic-disorder Child treated by Oriental Medicine and Play Therapy | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김윤희(대전대학교); 송현지(대전대); 한재경(대전대)"
] | A Case Study on Tic-disorder Child treated by
Oriental Medicine and Play Therapy
Song Hyun Jee, Han Jae Kyung, Kim Yun Hee
Department of Pediatrics, College of Oriental Medicine, Dae Jeon University
Objective : The purpose of this study is to report a case of tic-disorder child treated by
Oriental medicine and Play therapy
Methods:We treated the Tic-disorder child with herbal medicine (Yangsintangkamibang), acupuncture and Play therapy. Then we evaluated tic disorder by Yale Global Tic Severity Scale(YGTSS) and observed the progress of tic disorder with the play therapy.
Results : We treated a tic-disorder patient with oriental medicine, play therapy and had a good effect on a patient who had facial motor tic disorder. The patient's symptoms were improved and the YGTSS also decreased.
Conclusions : This study shows that co-treatment of oriental medicine and play therapy can be an effective treatment for tic disorder. And the further study is needed with more cases and longer duration.
Key words : Tic-disorder, Yangsintangkamibang, Acupuncture, Play therapy | 한의학 | null | kci_detailed_000250.xml | |||
ART001180377 | oai_dc | 주의력결핍과잉행동장애의 진단 및 평가 : 행동평정척도들을 중심으로 | Assesment and Diagnosis of Attention Deficit Hyperactivity Disorder(ADHD) | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"장규태(경희대학교); 한윤정(경희대학교)"
] | Assesment and Diagnosis of
Attention Deficit Hyperactivity Disorder(ADHD)
- Focusing on Behavior Rating Scales -
Han Yun Jeong, Chang Gyu Tae
Department of Pediatrics, College of Oriental Medicine, Kyunghee University
Objective : This study is to investigate the method for assesment and diagnosis of ADHD, especially focusing on behavior rating scales.
Methods : We searched the recent date of the publication and paper in ADHD
Results:For Assesment and Diagnosis of ADHD, various method such as interview with parents, child and teacher, behavior observation, behavior rating scales and neuropsychological test are used. The structured interview consists of the restrictive questions and response, and then have diagnostic algorithm, consequently can be used by untrained clinicians. Of the structured interview, standardization of K-SADS in Korean version is finished. Behavior rating scales, the form of parent, teacher and self-report questionnaires, are used as diagnosis and treatment evaluation of ADHD. Behavior rating scales consist of both ADHD-specific scales and broad-band scales designed to screen for various symptoms (including ADHD symptoms). ADHD-specific scales are useful in differential diagnosis, discrimination of subtype, treatment evaluation, However, broad-band scales are useful in preliminary examination.
The neuropsychological tests can evaluate attention deficit and effect of attention deficit on cognitive function and academic performance. The neuropsychological tests also used in diagnosis and treatment evaluation of ADHD.
Conclusion:For Assesment and Diagnosis of ADHD, various method are used, especially behavior rating scales are both useful and simple tool for diagnosis and treatment evaluation
Key word : Attention Deficit Hyperactivity Disorder, ADHD, Behavior rating scales | 한의학 | null | kci_detailed_000250.xml | |||
ART000974304 | oai_dc | 전염성 연속종 환아 1례 보고 | A case report of Molluscum Contagiosum in an infant | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김장현(동국대학교); 황영준(동국대)"
] | A Case Report of Molluscum Contagiosum in an Infant
Hwang Young Jun, Kim Jang Hyun
Department of Pediatrics, College of Oriental Medicine, Dongguk University
Objectives:The purpose of this study is to report Molluscum Contagiosum in an infant.
Methods:We reported 5-year-old male patient who suffered from Molluscum Contagiosum. We treated him with Gami-Okbyungpung-tang.
Results:After this treatment, the symptoms(papule on both thigh and gluteal sulcus region, itching) were improved.
Conclusion:We had good effects in oriental medical treatment on Molluscum Contagiosum. The further study is needed.
Key words:Molluscum Contagiosum, Gami-Okbyungpung-tang | 한의학 | null | kci_detailed_000250.xml | |||
ART001181111 | oai_dc | 사상체질음성분석기를 이용한 사상체질별 소아특성 연구 | A Study on the Children's characteristics by Sasang Constitution Analysed with PSSC-2004 | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"서영민(동국대학교); 김장현(동국대학교); 최은영(동국대)"
] | A Study on the Children's characteristics by Sasang Constitution Analysed with PSSC-2004
Choi Eun Young, Seo Young Min, Kim Jang Hyun
Department of pediatrics, College of Oriental Medicine, Dongguk University
Objective : The purpose of this study was to distribute children by Sasang constitution through voice analysis, and to investigate the difference of physical and physiological characteristics in constitutions.
Material and Methods : The subjects were 380 children aged between 5 and 6 who had been attending kindergartens. In April 2006, children were examined to make a diagnosis of Sasangin by PSSC-2004. Their parents responded the questionnaire on the children's characterist as eating habit, digestion, defecation, urination and perspiration.
Results : Sasang constitution composed of 55.0% Soeumin, 1.8% Soyangin and 43.2% were Taeumin, and there were no significant physical and physiological differences in those groups.
Conclusion : In this study, we tried to figure out some physical and physiological characteristics differences in Sasang constitution by using PSSC-2004.
Statistically, however, there were no remarkable differences and we needed more specific studies.
Key words : Sasang constitution, children, PSSC-2004, voice | 한의학 | null | kci_detailed_000250.xml | |||
ART000974302 | oai_dc | 아스퍼거 증후군 환아 증례 보고 | A Case Report of Asperger’s syndrome | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김윤희(대전대학교); 한재경(대전대학교)"
] | Objective : This study was to investigate the effect of oriental medical treatment for Asperger’s syndrome.
Methods : This patient was lack of social communication, interaction, imagination and motor coordination. It was due to Asperger’s syndrome. The patient was treated with Herbal medicine, acupuncture and play therapy. And we evaluated the case with The Australian scale for Asperger’s syndrome.
Results : Oriental medical treatment and play thrapy alleviated his symptoms of Asperger’s syndrome and anxiety.
Conclusions : We report the good result of oriental medical treatment on this case. The more study of oriental medical treatment for Asperger’s syndrome is needed. | 한의학 | null | kci_detailed_000250.xml | |||
ART001181109 | oai_dc | 소아를 주요 대상으로 하는 한의원 웹사이트의 분석 및 고찰 | Analysis of Oriental Pediatrics Clinic Web Sites in Korea | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"서영민(동국대학교); 김장현(동국대학교)"
] | Analysis of Oriental Pediatrics Clinic Web Sites in Korea
Seo Young Min, Kim Jang Hyun
Department of Pediatrics, College of Oriental Medicine, Dongguk University
Objectives : The Internet is closely related to the live of modern people in the 21st Century. With increasing interest in health and disease of children, the public has access to a growing supply of information on oriental pediatrics clinic through Internet.
The purpose of this study is to collect and analyze the Internet web sites concerning oriental pediatrics clinic in Korea, and study the effectiveness of internet toward oriental pediatrics.
Methods : We selected 42 web sites by searching for such keyword as child and oriental Medical clinic at korea major web search engine. The sites were evaluated and analyzed on the basis of 24 items under three evaluation criteria such as quality of contents, the easy of use, reliability of web sites.
Results: Study results indicated that 34% of web sites were built in 2004, 58% of oriental pediatrics clinic was located in Seoul & Kyunggi and 84% of them was connected network medical system. About health information was supplied in oriental pediatrics clinic web sites, the growth was high frequent information, 50% of web sites supplied high quality information and 19% of them was supplied high diversity information.
Conclusions: It is necessary to control system as information certification system in the area of oriental pediatrics clinic web sites.
Key words: internet, health information, oriental pediatrics, web sites | 한의학 | null | kci_detailed_000250.xml | |||
ART001180870 | oai_dc | 桑白皮가 항알러지 및 항염증반응에 미치는 영향 | In vitro and in vivo anti-inflammatory and anti-allergic responses caused by water extract of Mori Cortex | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이진용(경희대학교); 김덕곤(경희대학교); 조형준(경희대학교)"
] | 한의학 | null | kci_detailed_000250.xml | ||||
ART001180822 | oai_dc | 완관절 초음파통과속도를 이용한 골연령 측정값과 X-ray영상을 이용한 골연령 측정값의 비교 | A study on growth and development of children by Ultrasound transonic velocity of inferior radiocarpal joint | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이진용(경희대학교); 김덕곤(경희대학교); 윤경희(경희대학교); 고덕재(경희대학교); 유한정(경희대학교)"
] | Objectives : The purpose of this study was to suggest a new method for measurement of children's growth development. Ultrasound transonic velocity of inferior radiocarpal joint has some advantages that it is harmless to human body and apply a new analysis algorithm. it can be used for the diagnosis of bone age.
Methods : This clinical study have been carried out with the 117 case(male 68, female 49) of the children aged 5 to 16 years old who visited in Department of Pediatrics, ○○ university Oriental Hospital. Bone maturity is measured by Ultrasound transonic velocity and X-ray image of growth plate in inferior radiocarpal joint. This study were designed to investigate the relationship of the bone age by Ultrasound transonic velocity and X-ray image.
Result & Conclusion : The maturity of growth plate of inferior radiocarpal joint was correlated with age, height, weight, BMI in this study(P<0.001). The Ultrasound transonic velocity of inferior radiocarpal joint are sufficient diagnostic worth as an index to predict bone maturity. | 한의학 | null | kci_detailed_000250.xml | |||
ART001180821 | oai_dc | 청소년기 心膽虛怯 환아의 溫膽湯 치험 1례 | A clinical study on the effect of Ondam-tang on anxiety disorder in adolescence | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"하수연(동서한방병원); 이정림(동서한방병원); 하광수(동서한방병원); 김선미(동서한방병원); 송인선(동서한방병원)"
] | Objectives : The purpose of this study is to find out whether Ondam-tang has any effects on adolescence with anxiety disorder
Methods : The subject is in regard to 1 case with anxiety disorder who admitted at ○○ Oriental Medical hospital from 29th of June to 7th of July. The herbal therapy (Acupuncture, Moxa, Aroma therapy) is applied.
Results : After treatment, in a week, most of symptoms(insomnia, anxiety, the problem of verbal expression, chest discomfort, palpitation, anorexia, digestion, headache, dizziness, thirst, eye discomfort, etc) were subsided.
Conclusion : Anxiety disorder is similar to Simdamhugup in Oriental medicine. Ondam-tang has been used for long time for treatment on Simdamhugup. Ondam-tang is effective medication for adolescence with anxiety disorder, but more studies about adolescence and Oriental approach of psychiatrics are needed. | 한의학 | null | kci_detailed_000250.xml | |||
ART001204171 | oai_dc | 소아 아토피 피부염에 관한 임상적 고찰 | A Clinical Study of Atopic Dermatitis for Children | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이승연(동의대학교); 장지혜(동의대); 이준문(동의대)"
] | Objective : The objective of this study is to investigate treatment results and reasons of difference of treatment result.
Method : 22 patients with atopic dermatitis were evaluated for the symptoms and signs according to SCORAD index before and after Oriental medical treatment. And they were divided into two groups(G1: the lower group, G2: the higher group) with 30 scores in standard and analyzed for differences of treatment result.
Reasult : 22 patients's Change of total SCORAD index before and after treatment were 35.79±10.86 and period were 4.55±2.94 months. There were no significant differences between two groups in sex, age, congenital fever, onset and hospital treatment. There were many differences between two groups in the weakness of Digestive system. There were more familial histories in G2 than G1. Past years were 3.20±3.72 years in G1 and 1.75±1.68 years in G2. There were more deterioration fctors in G1 than G2. Sleep conditions before treatment were worse in G2 than G1 but all children except one were good after treatment. SCORAD index before treatment were worse in G2 than G1. The used herbal medicines were Bangpungtongsungsan gagambang, Yukmijihawangtang gagambang, Saenghyeolyunbuum gagambang. The most frequently used herbal medicine was Bangpungtongsungsan gagambang in G1, Yukmijihawangtang gagambang in G2.
Conclusion : On the basis of this study, we thought factors which affected treatment result were the weakness of Digestive system, past years, deterioration factors and SCORAD index before treatment. But this study's cases are small in number so more study is need. | 한의학 | null | kci_detailed_000250.xml | |||
ART001028444 | oai_dc | 심폐소생술후 발생한 저산소성 허혈성 뇌손상 患兒 치험 1例 | A Case Report of Hypoxic Ischemic Encephalopathy followed by Cardiopulmonary Resuscitation | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이진용(경희대학교); 김덕곤(경희대학교); 고덕재(경희대학교); 유한정(경희대학교); 조백건(경희대학교)"
] | Objective : To evaluate the effect of Oriental Medical Treatment on a patient with Hypoxic Ischemic Encephalopathy followed by Cardiopulmonary Resuscitation
Method : We applied various methodology of Oriental Medical Treatment including Acupuncture, Electroacupuncture, Physical treatment, Herbal Medicine, Moxibustion treatment and Western medication as well.
Result : Herbal medicine was applied on the basis of the patient's history. We applied formular to remove phelgm as a pathogenic factor after Hypoxic Ischemic Encephalopathy. At the same time, considering the patient spent more than a month in ICU lacking appropriate nutrition, we used formuli on the basis of "Deficiency of Spleen" focusing to vitalize the function of digestive system. As the condition of the patient changed, we also adapted formular accordingly. We prescribed Herbal medication to strengthen Yin and Yang equally as she got hospitalized for long time. Also we applied Acupuncture treatment and Moxibustion treatment to control Qi flow. The general condition of the patient got better with successful removal of Foley catheter and elevated Glasgow Coma scale. We used Electroacupuncture, Physical treatment and Western medication at the same to get maximized effect on relaxing the contracted muscle. According to the Modified Ashworth Scale (MAS), we have some changes in muscle spasticity but later, the effect was not that significant.
Conclusion : We had a patient with Hypoxic Ischemic Encephalopathy followed by Cardiopulmonary Resuscitation. In the management of Hypoxic Ischemic Encephalopathy, Conservative treatmennts are the mainstream but there are not many alternatives. Therefore, We suggest that Oriental medical approach may contribute to the management of Hypoxic Ischemic Encephalopathy. | 한의학 | null | kci_detailed_000250.xml | |||
ART001028600 | oai_dc | 한방 소아과에 내원한 환아 보호자 일반적인 인식도 조사와 한약치료후의 반응에 대한 후향적 연구 | A Survey on Parent's Recognition and Retrospective Study on Effect of Herbal Medication | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김윤희(대전대학교); 채호연(대전대); 한재경(대전대)"
] | 한의학 | null | kci_detailed_000250.xml | ||||
ART001028738 | oai_dc | 儒門事親에 나타난 小兒와 관련된 理論과 治法에 대한 考察 | A Study on the Therapeutic Theory of Rumenshiqin(儒門事親) concerning Pediatrics | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김장현(동국대학교); 정우병(동국대); 김기현(동국대); 장규태(동국대)"
] | 한의학 | null | kci_detailed_000250.xml | ||||
ART001180820 | oai_dc | 초등학교 어린이의 허약상태 및 성장부진에 對한 報告 | The statistical study of Weakness and the Delayed Growth on primary school children | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"왕향란(샘한방병원); 장보형(샘한방병원); 권미원(샘한방병원)"
] | Objective : As the meaning of collective medical examination, the purpose of this study is to investigate distribution of weak children by measurement according to the five group of weakness (Lung, Heart, Pancreas, Liver, Kidney), and the relationship between the five group of weakness and the Growth failure on primary school children.
Methods : This study is composed of 1078 children who attend A primary school in ○○ city. They are divided into 6 groups by grade and for the purpose of effective comparison, The five weak symptoms are studied to determine the association with growth stature among children and we standardize the weak children's height into percent according to age.
Results: When each weak children controled grade, sex, body-weight, existence or nonexistence of personal history, physical exercise so on, relatively group of weakness for kidney is statistically less then opposite group and the rest of the people statistically have no significant difference.
Conclusions: From the above result, it is suggested that the statistical relationship between the weakness for kidney and growth(p<0.001)). It looks forward to have contributed to collective medical examination and children's health care by oriental medical treatment. | 한의학 | null | kci_detailed_000250.xml | |||
ART001180871 | oai_dc | 加味養神湯이 低溫 스트레스에 미치는 영향 | The Effects of Kamiyangsintang(KYT) to Cold-Stress | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김윤희(대전대학교); 정창호(대전대); 한재경(대전대)"
] | Objective : The study was aimed to evaluate the anti-stress effect of KYT on the cold-stressed Mice.
Methods : The experimental animals were stressed in cold room (4±0.5℃) for one hour in a day during two weeks, and administred 131mg/100g KYT extract for two weeks before stress. For two weeks, while the experiment was taking place, we conducted a research about the change of weight and content of norepinephrine, epinephrine, dopamine, cortisol and GOT, GPT in the mice serum.
Results : KYT extract significantly inhibited the decrease of body weight induced by stress, compared with the control group. KYT extract had no significant decreasing effect on the change of content of the serum GOT but had significant decreasing effect on the change of content of the serum GPT compared with the control group. KYT extract had significant decreasing effect on the change of content of the serum cortisol compared with the control group. KYT extract had decreasing effect on the change of content of the serum dopamine compared with the control group. KYT extract had no decreasing effect on the change of content of the serum norepinephrine compared with the control group.
KYT extract had significant decreasing effect on the change of content of the serum epinephrine compared with the control group.
Conclusions : According to the above results, it is concluded that KYT will be useful as a preventive and remedy against stress disease. | 한의학 | null | kci_detailed_000250.xml | |||
ART001028599 | oai_dc | 모 한방병원 소아과 외래 환자의 주소증에 대한 연구 (’01-’04년) | A Study of the Chief Complaint of Pediatric Outpatients in the Oriental Hospital | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김장현(동국대학교); 최은영(동국대); 장규태(동국대)"
] | Objective : The purpose of this study was to investigate chief complaints of pediatric outpatients in the oriental hospital and search for a trend of patients and their symtoms.
Method : The study was composed of 2,915 new patients aged between 0 and 20 who had been visited pediatrics in ○○ university oriental hospital from 2001 to 2004.
Results : The percentage of new patients decreased every year with 30.7% in 2001, 25.5% in 2002, 24.1% in 2003, 17.8% in 2004. The age distribution showed 9.9% in infancy patients, 62.6% in early childhood, 16.8% in late childhood, 10.6% in adolescence. The percentage of infants decreased every year with 13.3% in 2001, 9.4% in 2002, 8.8% in 2003, 7.1% in 2004. The percentage of adolescents increased every year with 8.0% in 2001, 9.6% in 2002, 12.8% in 2003, 13.5% in 2004. Systemic division of chief complaints was respiratory symtoms(37.6%), general symtoms(26.1%), digestive symtoms(19.2%), skin symtoms(6.8%), nervous and mental symtoms (6.1%), urinary symtoms(2.2%), musculoskeletal symtoms(1.3%) and others(0.7%) in order of frequency. The main chief complaints were nasal mucus/obstruction(17.5%), weakness(16.9%), cough(12.8%), loss of appetite(9.8%), inappropriate growth(4.3%), atopic skin problem(3.4%), repeated common cold(2.4%), abdominal pain(2.4%), vomiting(2.2%), diarrhea(2.0%) and fever (1.9%). Loss of appetite, inappropriate growth and repeated common cold increased every year. Diarrhea and convulsion decreased every year.
Conclusions : The two main causes of visit of patients were respiratory problems and improvement of general condition. More data of patients should be accumulated for further study. Not only analysis according to chief complaint, but also analysis according to diagnosis will accomplish more aaccurate information about disease of childrens in the future. | 한의학 | null | kci_detailed_000250.xml | |||
ART001028737 | oai_dc | Cerebellar Atrophy로 인해 유발된 Spinocerebellar Ataxia 患兒 1例 報告 | The Clinical Study on Spinocerebellar Ataxia with Cerebellar Atrophy | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이정림(동서한방병원); 하광수(동서한방병원); 김선미(동서한방병원); 하수연(동서한방병원); 송인선(동서한방병원)"
] | 저자는 Brain MRI 상 Cerebellar atrophy로 인한 척수소뇌성 운동실조증으로 진단받은 6세 환아의 Ataxia, Dysarthria, 頭部振顫症, 眼振 등에 대해 한방적 치료 후 호전도가 있었기에 이에 證例報告하는 바이다.특히 頭振, 眼振과 같은 振顫질환과 실조증에 대하여 頭鍼시술이 유효성이 컸으며, 五遲 五軟證에 대하여서 肝, 腎正格과 六味地黃湯의 장기 투여가 효과가 있었다.일반적인 SCA, ADCA가 청, 장년기 이후에 발생하고 유전적인 경향이 큰 것에 반해 在胎시 큰 이상없이 생후 특발적으로 발생한 척수소뇌성 운동실조에 대하여서는 한방적으로 證例報告 된 바가 드문 실정으로 유, 소아의 이러한 질환에 대한 진일보된 연구과 함께 평가척도나 치료방법적인 면에서의 考察이 더욱 필요하리라 사료된다. | 한의학 | null | kci_detailed_000250.xml | |||
ART001180819 | oai_dc | 歸脾湯加減方이 구속 Stress 유발 白鼠에 미치는 영향 | The effects of Quibitanggagam(QBT) on the stress due to restraint method in rat | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김장현(동국대학교); 권혁란(동국대); 김기현(동국대); 장규태(동국대)"
] | Objectives : This study was aimed to find out the anti-stress and protective-memory effect of Quibitanggagam(QBT) on stress of rats
Methods : This experimental study was conducted with elevated plus maze test, passive avoidance test, morris water maze test, and consequently density of AchE reactivity in the CA1 of hippocampus to research the learning and memory of rats affected by restraint stress.
Results : Passive avoidance test revealed that time latency of retention test for QBT+Stress group significantly decreased on 2, 3rd day. Morris water maze revealed that acqusitive ability of QBT+Stress group significantly improved on 2, 3rd day and retentive ability of QBT+Stress group was significantly improved on 7th day. Elevated plus maze test revealed that latency in open arm of QBT+Stress group significantly decreased and locomotor activity(number of entered arm) of QBT+Stress group was significantly increased. The values of density of AchE stained nuclei in the CA1 of hippocampus QBT+Stress group was significantly increased compared with SAL+Stress group.
Conclusion : According to the above results, it is concluded that QBT will be useful as a remedy against stress disease and improving memory. | 한의학 | null | kci_detailed_000250.xml | |||
ART001028596 | oai_dc | 저산소성 허혈성 뇌손상을 받은 WPW 증후군 환아 증례 1례 | A case report of Wolff-Parkinson-White syndrome with Hypoxic ischemic encephalopathy | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"하광수(동서한방병원); 이정림(동서한방병원); 김선미(동서한방병원); 하수연(동서한방병원); 박준범(동서한방병원); 송인선(동서한방병원)"
] | Objective:There were few reports on the treatment of Wolff-Parkinson-White syndrome with Hypoxic ischemic encephalopathy. We treated a Wolff-Parkinson-White syndrome with Hypoxic ischemic encephalopathic patient with Oriental medical approach, and got a significant result. This treatment shows the possibility of healing Wolff-Parkinson-White syndrome with Hypoxic ischemic encephalopathy. So we are reporting this case.
Method: Acupuncture treatment, herb medication, rehabilitation therapy were applied for treating patient's chief symptom.(involuntary movement, dystonia, aphasia, fever, perspiration)
Results: Consciousness loss in acute stage of Hypoxic ischemic encephalopathy can be considered as Mental Confusion due to Phlegm(Dammisimgyu) in veiw point of Oriental medicine. Wolff-Parkinson-White syndrome can be considered as Sudden Palpitation(Gyounggye) in veiw point of Oriental medicine. After oriental medical treatment, patient's chief symptoms were improved.
Conclusion: More study about oriental medical treatment on Wolff-Parkinson-White syndrome with Hypoxic ischemic encephalopathy is needed. | 한의학 | null | kci_detailed_000250.xml | |||
ART001028448 | oai_dc | 한방병원 산후조리센터 내 신생아의 Rota Virus 감염증에 대한 임상적 고찰 | A Clinical Study for Rota Virus Infection of Neonates in Oriental Medicine Hospital Postpartum Care Center | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김선미(동서한방병원); 이정림(동서한방병원); 하광수(동서한방병원); 하수연(동서한방병원); 송인선(동서한방병원)"
] | Objective : The aim of this study is to investigate rota virus infection of neonates in the Postpartum care center.
Methods : This clinical study was carried out with the 205 neonates who admitted to the Postpartum Care Center of ○○ Oriental Medicine Hospital, from July, 2004 to July, 2005. Stools were examined daily with Rotazyme ELISA tests(Bio Line Rota Virus, SD Standard Diagnostics, INC.) for 3 days from the day of admission. Supplementary test was examined when change was found in stools.
Results : Among 205 newborn babies, 58 cases turned out to be positive. The positive rate of rota virus was not significantly related to sex, birth weight, gestation age. But, it was significantly related to delivery method and it was higher in caesarean section group. The manifestation rates of symptoms were 51.7% in Rotazyme positive neonates. In the Rotazyme positive 58 cases, 30 cases(51.7%) had diarrhea, 8 cases had fever(13.8%), 1 case(1.7%) had vomiting. The positive rate of rota virus was higher during from october to march. There were 190 cases(92.2%) of mixed feeding and 15 cases(7.8%) of artificial feeding. There was significance between breast feeding and the positive rate of rota virus. There was no significance between hospital of birth and the rate of positive rotazyme test.
Conclusions : A further study of neonates in postpartum care center is necessary as preference of postpartum care center was increased. And the oriental medicine treatment of rota virus is expected to be effective, so a further study is necessary. | 한의학 | null | kci_detailed_000250.xml | |||
ART001028736 | oai_dc | 季節別 症狀을 중심으로 한 小兒感冒의 임상적 고찰 | The Clinical Study on Childhood Common Cold in Four Seasons | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"백정한(대구한의대학교); 서정민(대구한의대); 구진숙(대구한의대)"
] | Objectives: This study was performed to investigate the character of childhood common cold according to four seasons.
Methods: We made an investigation into medical record of 432 children under fifteen years of age who visited pediatrics or emergency room suffering from common cold. We analyzed the principal and secondary symptoms of the children classifying four seasons by SPSSⓇ 12.0 for windows.
Results: Male to female ratio were 1.42:1, the average of age was 3.86 years old.
Distribution of principal symptoms was that nasal discharge was 231(56.1%), cough was 223(54.1%), nasal obstruction was 162(39.3%), secretion and sputum were 126(30.6%), fever was 121(29.4%), and headache was 13(3.2%). Out of these fever occurred in high frequency during spring and summer, nasal obstruction occurred in high frequency during spring and autumn. Distribution of secondary symptoms was that throat pain was 93(22.6%), otalgia was 39(9.5%), vomiting was 35(8.5%), abdominal pain was 30(7.3%), anorexia was 23(5.6%), sweating was 21(5.1%), diarrhea was 19(4.6%), and startle was 11(2.7%). Out of these otalgia occurred in high frequency during spring and summer, diarrhea occurred in high frequency during autumn and winter.
Conclusions: A few symptoms can be the character according to four seasons. | 한의학 | null | kci_detailed_000250.xml | |||
ART001180769 | oai_dc | 當歸飮子 加減方의 처방별 (A, B) 아토피성 알레르기반응 조절 효과 비교 연구 | A Comparative Study of Regulatory Effect of Atopic Allergic Reaction by Prescriptions (A, B) | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박은정(원광대학교); 이해자(원광대학교); 한경훈(원광대)"
] | Objective : Danguieumja-gagambang (DGEJGB), a traditional Korean prescription, has been used as therapeutics for allergic diseases such as atopic dermatitis (AD). In this study, we compared with regulatory Effect of Atopic Allergic Reaction by Prescriptions A and by Prescriptions B.
Methods : To evaluate and compare the atopic allergic effectiveness of two prescription (A, B) of DGEJGB, the author investigated a possible effect of DGEJGB on mast cell-mediated allergic reaction, cytokine secretion and mRNA expression in vivo and in vitro.
Results : Mast cells are a potent source of mediators that regulate the inflammatory response in allergic reaction. In mice orally administered A, B of DGEJGB (0.01, 0.1 and 1.0 g/kg) for 1 h, compound 48/80-induced ear swelling was significantly reduced. Significant reduced levels (P < 0.05) of tumor necrosis factor (TNF)-α was observed in the human mast cell line (HMC-1) with DGEJGB (A). IL-6 and IL-8 secretion were significantly inhibited by DGEJGB (A, B). In addition, TNF-α and IL-8 mRNA expression were reduced by DGEJGB (A) at the dose of 0.01 mg/ml without cell toxicity.
Conclusions : These results suggest that DGEJGB (A) contributes to the treatment of atopic allergic reactions rather than DGEJGB (B), and that its action may be due to inhibition of cytokine secretion and mRNA expression HMC-1. | 한의학 | null | kci_detailed_000250.xml | |||
ART001028735 | oai_dc | 절식요법이 2명의 비만청소년의 체성분 변화에 미치는 영향 | The Effect of the Fasting for Body Composition Changes in Two Obese Adolescents | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김홍배(한양대학교); 이승연(동의대학교); 정선희(동의대)"
] | Objectives : The purpose of this study is to investigate the effect of fasting therapy on the changes of body composition in obese adolescents.
Methods : We examined the body composition of obese adolescents three times; before fasting, on the second refeeding day, two or four weeks later.
Results : Body weight, body mass index(BMI), basal metabolic rate(BMR) and lean body mass(LBM) were decreased during the fasting, whereas percent-fat was increased. After fasting, patients have the dietary period. During this period BMR and LBM were increased and the decrease of percent-fat was continued.
Conclusions : It seems that fasting therapy with keeping up well-controlled dietary period and receiving oriental medical management can be useful to decrease percent-fat in obese patients. | 한의학 | null | kci_detailed_000250.xml | |||
ART001180770 | oai_dc | 비전형자폐 소아 환자 치험 2례 보고 | Two Cases Report about Atypical Autistic Children | {
"journal_name": "대한한방소아과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"장지혜(동의대); 임영우(동의대); 이승연(동의대)"
] | Objective : The purpose of this study is to assess the clinical effect of Yukmijihawangtang gamibang on autism.
Methods : This clinical study was carried out with two atypical autistic children. We treated them with the herb medicine(Yukmijihawangtang gamibang) for several months and observed them once a month. And we checked the dregrees of autism with Korean-Autism Diagnostic Scale at June 29 and October 13.
Results : Two cases's dregrees of autism were improved significantly. Autistic probability of case 1 was below the average at first test and very low at second test And case 2 was above the average at first test and very low at second test. And language was improved at last.
Conclusion : Yukmijihawangtang gamibang was effective in the treatment of autism and more study about this disease is needed. | 한의학 | null | kci_detailed_000250.xml | |||
ART002018110 | oai_dc | Men’s Health: What Should We Know? | Men’s Health: What Should We Know? | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김세웅(Catholic Integrative Medicine Research Institute)"
] | 비뇨기과학 | null | kci_detailed_000250.xml | ||||
ART002018119 | oai_dc | The Testis Completely Replaced by a Huge Epidermal Cyst in an Older Man | The Testis Completely Replaced by a Huge Epidermal Cyst in an Older Man | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Kyung Kgi Park(Jeju National University); Chang Lim Hyun(Jeju National University); Sung Dae Kim(Jeju National University); Young Joo Kim(Jeju National University); Jung Sik Huh(Jeju National University)"
] | Epidermal cysts are commonly encountered, slow-growing superficial cysts in the hair-bearing areas of the body, and are usually discovered in the second and fourth decades of life. These cysts tend to be superficial, meaning that they can be easily found by ultrasound and digital palpation at a moderate degree of growth. However, we found a huge testicular cyst that went undetected until old age. In this report, we describe the interesting case of a patient in whom the right testis was totally replaced with an epidermal cyst. The cyst was found by ultrasonography and further evaluated with magnetic resonance imaging. We performed orchiectomy under the impression of an epidermal cyst. The pathologic report confirmed this clinical impression. Over 24 months of follow-up, we did not find any recurrence of a growing mass on the testis. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002018120 | oai_dc | Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies | Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"문두건(고려대학교)"
] | 비뇨기과학 | null | kci_detailed_000250.xml | ||||
ART002018111 | oai_dc | Glans Penis Augmentation Using Hyaluronic Acid Gel as an Injectable Filler | Glans Penis Augmentation Using Hyaluronic Acid Gel as an Injectable Filler | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"문두건(고려대학교); Tae Il Kwak(Korea University College of Medicine); Je Jong Kim(Korea University College of Medicine)"
] | Glans penis augmentation (GPA) has received little attention from experts despite the existence of a subset of patients who may be dissatisfied with a small glans or poor tumescence of the glans during erection. Recently, GPA using an injectable filler or implantation of a graft or filler has been developed. Despite a demanding injection technique and inevitable uneven undulation of the glandular surface, GPA using injectable hyaluronic acid (HA) gel is a novel and useful therapy and an effective and safe procedure for soft tissue enhancement. For long-term presence of implants, timed supplementation can be used similar to that for fascial plasty. In complications such as mucosal necrosis of the glans penis, most cases occur from the use of non-HA gel or an unpurified form and misunderstanding of the management protocol for immediate side effects. Currently, GPA using injectable HA gel is not recommended in the International Society for Sexual Medicine guideline due to possible sensory loss. In a 5-year long-term follow-up of GPA by subcutaneous injection of HA gel, the residual volume of implants decreased by 15% of the maximal glandular circumference, but was still effective for alleviating the hypersensitivity of the glans penis in premature ejaculation patients. For efficacy in premature ejaculation, selection of appropriate candidates is the most important factor for success. GPA does not harm erectile function and is less invasive and irreversible compared to dorsal neurectomy. To refine the procedure, more interest and well-designed studies are required for the establishment of the procedure. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002018117 | oai_dc | Chronic Prostatitis: A Possible Cause of Hematospermia | Chronic Prostatitis: A Possible Cause of Hematospermia | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이길호(단국대학교)"
] | Purpose: While hematospermia is mainly caused by genitourinary inflammatory disorders, very few studies have been published on prostatitis-associated hematospermia (PAH) diagnosed using robust prostatitis evaluation methods. Therefore, we have evaluated the incidence of PAH by using systematic methods for evaluating prostatitis.Materials and Methods: We evaluated 37 hematospermia patients from a single hospital over the last five years. We classified the patients into PAH versus hematospermia without any evidence of prostatitis (HWP) by using a NIH-Chronic Prostatitis Symptom Index questionnaire and expressed prostatic secretion studies.Results: The mean age was 55.89±14.87 years, and the patients were grouped into two groups: one group had 12 HWP patients and the other 25 PAH patients. PAH patients were further sub-classified: chronic bacterial prostatitis (3 patients), chronic nonbacterial prostatitis (10 patients), prostadynia (7 patients), and asymptomatic prostatitis (5 patients). We found Enterococcus faecalis in the three chronic bacterial prostatitis patients. We could not find any statistically significant difference between the PAH and the HWP groups in terms of the age interval, serum prostate-specific antigen level, and prostate volume. Even though there was no statistically significant difference in the items about urination between the two groups, we found a statistically significant difference in the quality of life (QoL) impact for the patients in this study.Conclusions: Two-thirds of the hematospermia patients were associated with some evidence of prostatitis. Further, the patients with PAH revealed poor QoL compared with the patients with HWP. Therefore, we must evaluate the presence of prostatitis in hematospermia patients and alleviate the prostatitis-associated symptoms to improve their QoL. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002018112 | oai_dc | Current Status and Clinical Studies of Oriental Herbs in Sexual Medicine in Korea | Current Status and Clinical Studies of Oriental Herbs in Sexual Medicine in Korea | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"신유섭(Chonbuk National University); Chen Zhao(Shanghai Jiao Tong University); Li Tao Zhang(Chonbuk National University); Jong Kwan Park(Chonbuk National University)"
] | Erectile dysfunction (ED) is one of the most common diseases among aging men. Although previous studies have shown that type 5 phosphodiesterase inhibitors (PDE5-Is) are very effective for the treatment of ED, many researchers are currently attempting to identify therapeutic agents from natural sources with comparable or better effects than PDE5-Is. Herbal medicine is thought to be advantageous because it is natural; moreover, it not only treats isolated symptoms, but also maintains general well-being. Furthermore, since newly created chemical compound libraries have limited structural diversity with regard to pharmaceutical agents, more attention has recently been paid to the ability of oriental herbs to enhance physical health, including sexual function. Herein, we review the current status of Korean preclinical or clinical studies of the application of oriental herbs to sexual medicine. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002018113 | oai_dc | Protective Effects of KH-204 in the Bladder of Androgen-Deprived Rats | Protective Effects of KH-204 in the Bladder of Androgen-Deprived Rats | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"배웅진(가톨릭대학교); 하유신(가톨릭대학교); Jin Bong Choi(The Catholic University of Korea); Kang Sup Kim(The Catholic University of Korea); Su Jin Kim(The Catholic University of Korea); 조혁진(가톨릭대학교); 홍성후(가톨릭대학교); 이지열(가톨릭대학교); Zhiping Wang(Second Hospital of Lanzhou University); Sung-Yeoun Hwang(Korea Bio Medical Science Institute);... | Purpose: We investigated the protective effects of the herbal formulation KH-204 in the bladder of androgen-deprived rats.Materials and Methods: Male rats aged eight weeks were randomly divided into four groups, containing eight rats each: sham operation only (normal control group), androgen-deprived only (androgen-deprived control group), and androgen-deprived followed by treatment with 200 mg/kg or 400 mg/kg of KH-204. After 0.5 mg/kg of leuprorelin was subcutaneously injected in the androgen-deprived groups, the oral administration of either distilled water in the two control groups or KH-204 in the treatment group was continued for four weeks. Serum testosterone levels, RhoGEF levels, nitric oxide (NO)-cyclic guanosine monophosphate (cGMP)-related parameters, oxidative stress, and histologic changes were evaluated after treatment.Results: Treatment with the herbal formulation KH-204 (1) increased serum testosterone levels; (2) restored the expression of RhoGEFs, endothelial NO synthase, and neuronal NO synthase; (3) increased the expression of superoxide dismutase; and (4) decreased bladder fibrosis.Conclusions: Our results suggest that the positive effects of KH-204 on the urinary bladder may be attributed to its antioxidant effects or to an elevation in NO-cGMP activity. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002018114 | oai_dc | Seasonal Variation of Urinary Symptoms in Korean Men with Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia | Seasonal Variation of Urinary Symptoms in Korean Men with Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"최호철(연세대학교); 권종규(연세대학교 세브란스병원); 이주용(연세대학교 세브란스병원); 한장희(연세대학교 세브란스병원); 정해도(연세대학교 세브란스병원); 조강수(연세대학교)"
] | Purpose: To examine seasonal variations in urinary symptoms in Korean men with lower urinary tract symptoms and benign prostatic hyperplasia (LUTS/BPH).Materials and Methods: Records were obtained from a consecutive database of LUTS/BPH patients from March 2010 to February 2014. A total of 1,185 patients were suitable for analysis. The International Prostate Symptom Score (IPSS), uroflowmetric parameters, prostate volume-related parameters, and serum prostate-specific antigen levels were evaluated.Results: Based on the month during which they were examined, patients were categorized into cold, hot, or intermediate season groups. The IPSS score was significantly different between the cold and the hot season groups (17.3±6.9 vs. 16.1±7.4, respectively; p=0.020). Storage symptom scores were significantly aggravated in the cold (6.8±3.3; p=0.030) and intermediate groups (6.9±3.5; p=0.032) compared with the hot season group (6.3±3.4), with this observation primarily driven by the individual scores for frequency and urgency. Quality of life (QOL) scores were worse in the cold compared with the hot season group (4.0±1.1 vs. 3.8±1.1, respectively; p=0.012). There were also significant differences between the cold and hot season groups in voided volume (278.7±148.5 vs. 255.9±145.1, respectively; p=0.034) and postvoid residual volume (26.4±37.6 vs. 32.2±41.0, respectively; p=0.039).Conclusions: Different urinary symptoms and uroflowmetric parameters were associated with changes in seasons. QOL and IPSS parameters might be worse in cold weather seasons compared with hot weather seasons. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002018115 | oai_dc | Risk Factors for Transient Urinary Incontinence after Holmium Laser Enucleation of the Prostate | Risk Factors for Transient Urinary Incontinence after Holmium Laser Enucleation of the Prostate | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"남종길(부산대학교); Hyeon Woo Kim(Pusan National University Hospital); Dong Hoon Lee(Pusan National University Yangsan Hospital); Ji-Yeon Han(Pusan National University Yangsan Hospital); 이정주(부산대학교); Sung-Woo Park(Pusan National University Yangsan Hospital)"
] | Purpose: To investigate the factors associated with the occurrence of and recovery from transient urinary incontinence (TUI) after holmium laser enucleation of the prostate (HoLEP).Materials and Methods: From March 2009 to December 2012, 391 consecutive patients treated with HoLEP for benign prostatic hyperplasia were enrolled. Information regarding age, prostate volume, International Prostate Symptom Score, Overactive Bladder Symptom Score, peak urinary flow rate, postvoid residual urine, and operation time was collected. TUI was defined as a patient complaint of urine leakage, regardless of type. Logistic regression was used to investigate the factors associated with the occurrence of TUI, and the Kaplan-Meier test was used to analyze the TUI recovery period. Results: TUI after HoLEP occurred in 65 patients (16.6%), 52 patients of whom (80.0%) showed recovery within three months. Stress and urge urinary incontinence and postvoid dribbling occurred in 16 patients (4.1%), 29 patients (7.4%), and 33 patients (8.4%), respectively. Age (odds ratio [OR]=3.494; 95% confidence interval [CI]=1.565∼7.803; p=0.002) and total operation time (OR=3.849; 95% CI=1.613∼9.185; p=0.002) were factors that significantly affected the occurrence of TUI.Conclusions: TUI, defined as any type of urine leakage, occurred after HoLEP in some patients, most of whom recovered within three months. Stress urinary incontinence occurred in only 4% of patients after HoLEP. Age and total operation time were associated with the occurrence of postoperative TUI. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002018116 | oai_dc | Penile Fracture: Our Experience in a Tertiary Care Hospital | Penile Fracture: Our Experience in a Tertiary Care Hospital | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Rajkumar Singha Mahapatra(SSKM Hospital, Kolkata, India); Anup Kumar Kundu(SSKM Hospital, Kolkata, India); Dilip Kumar Pal(SSKM Hospital, Kolkata, India)"
] | urpose: Penile fracture is rare, but it is a urological emergency that always requires immediate attention. Moreover, penile fracture has been reported more frequently in recent years. It may have devastating physical, functional, and psychological consequences if not properly managed in time.Materials and Methods: The objective of this study was to highlight the causes, clinical presentation, and outcomes of cases of penile fracture. This was a prospective observational study extending from November 2012 to November 2014. Each patient underwent a thorough clinical evaluation and received proper treatment.Results: Twenty patients with penile fracture, aged 19 to 56 years (mean, 28 years) were evaluated in this study. Vaginal intercourse was the most common mechanism of injury. Most of the patients (95%) were diagnosed clinically with a proper history and clinical examination. Nineteen patients were treated surgically. The patients underwent six months of follow-up, and were evaluated with local examinations, questionnaires, and colour Doppler ultrasonography as necessary.Conclusions: Although penile fracture is an under-reported urological emergency, its incidence is increasing. It is usually diagnosed based on a clinical examination, but ultrasonography can be very helpful in diagnosis. Especially in cases where treatment is delayed, surgery is preferable to conservative management, because it is associated with better outcomes and fewer long-term complications. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002018118 | oai_dc | The Effect of Vitis vinifera L. Juice on Serum Levels of Inhibin B, Sperm Count in Adult Male Rats | The Effect of Vitis vinifera L. Juice on Serum Levels of Inhibin B, Sperm Count in Adult Male Rats | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Mohammad Reza Afzalzadeh(Shahid Chamran University of Ahvaz); Akram Ahangarpour(Ahvaz Jundishapur University); Ashraf Amirzargar(Jundishapur University of Medical Sciences, Ahvaz, Iran); Mohammad Kazemi Varnamkhasti(Shahid Chamran University of Ahvaz); Hadi Ganjalidarani(Shahid Chamran University of Ahvaz)"
] | Purpose: Vitis vinifera is a species of Vitis that is native to the Mediterranean region, central Europe, and southwestern Asia, and has been used as a drug in traditional medicine. Traditional medicinal plants have been used for medical purposes with increasing effectiveness. It is important to identify drugs that inhibit spermatogenesis. Therefore, the present study aimed to investigate the effect of grape juice (GJ) on serum levels of inhibin B and sperm count in normal male rats.Materials and Methods: Thirty-five adult male rats were randomly divided into five groups, each containing seven rats. Rats in the control group received 1 mL of normal saline over the course of the study. The experimental groups received GJ (100, 200, 400, and 1,600 mg/kg, orally, for 35 days consecutively). At the end of the treatment period, fertility indices were measured, including body weight difference, sex organ weight, sperm motility and count, epididymal sperm reserve, daily sperm production (DSP), and serum inhibin B levels.Results: We found that GJ reduces body weight difference, was associated with decreased sperm motility and count in all treatment groups (p≤0.05 and p≤0.001, respectively). Moreover, DSP was significantly decreased in all treatment groups compared to the control group (p≤0.05), except in the group receiving 100 mg/kg of GJ. Inhibin B levels were significantly decreased in all treatment groups (p≤0.05).Conclusions: The results of our study suggest that GJ in all doses, but especially in higher doses, may decrease fertility in male rats. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001938290 | oai_dc | The Efficacy of Mirodenafil for Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Middle-Aged Males | The Efficacy of Mirodenafil for Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Middle-Aged Males | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"공도훈(부산대학교); 박현준(부산대학교); 윤창진(부산대학교); 박남철(부산대학교)"
] | Purpose: The aim of this study was to investigate the efficacy of mirodenafil in middle-aged male patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
Materials and Methods: Eighty-eight males with CP/CPPS were randomized to receive either levofloxacin (500 mg/d) (group L, 40 patients) or levofloxacin (500 mg/d) and mirodenafil (50 mg/d) (group ML, 48 patients) for six weeks. The International Prostate Symptom Score (IPSS), National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI), and erectile function (EF) domain scores of the International Index of Erectile Function (IIEF) questionnaire were used to grade symptoms at baseline and 6 weeks after treatment.
Results: The mean change in total IPSS from baseline was higher in group ML than that in group L (group L, −1.1 vs. group ML, −4.3; p＜0.05). Significant improvements were also seen in the IPSS voiding subscore (group L, −0.7 vs. group ML, −3.0; p＜0.05). Changes observed in the NIH-CPSI of group ML at six weeks were greater than those at baseline (group L, −3.2 vs. group ML, −7.2; p＜0.05). Significant improvements were seen in the NIH-CPSI voiding (group L, −0.5 vs. group ML, −1.7; p＜0.05) and quality of life domains (group L, −1.0 vs. group ML, −1.8; p＜0.05). Group ML showed a significantly greater increase in the IIEF-EF score than did group ML (group L, +0.2 vs. group ML, +7.8; p＜0.05).
Conclusions: Mirodenafil (50 mg once daily) was well tolerated and resulted in significant symptomatic improvement in middle-aged males with CP/CPPS. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001938291 | oai_dc | Effects of Hydro-Alcoholic Extract of Rhus coriaria (Sumac) Seeds on Reproductive Complications of Nicotinamide-Streptozotocin Induced Type-2 Diabetes in Male Mice | Effects of Hydro-Alcoholic Extract of Rhus coriaria (Sumac) Seeds on Reproductive Complications of Nicotinamide-Streptozotocin Induced Type-2 Diabetes in Male Mice | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Akram Ahangarpour(Ahvaz Jundishapur University); Ali Akbar Oroojan(Ahvaz Jundishapur University); Hamid Heidari(Qom University); Ehsan Ghaedi(Ahvaz Jundishapur University); Mohammad Reza Rashidi Nooshabadi(Ahvaz Jundishapur University)"
] | Purpose: The purpose of this study was to investigate the effects of the hydro-alcoholic extract of Rhus coriaria seeds on the reproductive system of nicotinamide-streptozotocin-induced type-2 diabetic mice.
Materials and Methods: In this experimental study, 56 male Naval Medical Research Institute mice were randomly divided into seven groups (n=8): control; diabetic mice; diabetic mice administered glibenclamide (0.25 mg/kg); diabetic mice who received the hydro-alcoholic extract of R. coriaria seeds (200 and 400 mg/kg groups); and normal mice who received this extract (200 and 400 mg/kg groups). Diabetes was induced by intraperitoneal administration of streptozotocin (65 mg/kg) 15 minutes after an injection of nicotinamide (120 mg/kg). Then, glibenclamide and the above mentioned extract were administered orally for 28 consecutive days. Twenty-four hours after the last treatment, serum samples, the testes, and the cauda epididymis were removed immediately for hormonal, testis morphology, and sperm parameter assessments.
Results: Body and testicular weight, sperm count and viability, and serum luteinizing hormone, follicle-stimulating hormone and testosterone levels were significantly lower in the diabetic mice (p＜0.05). The diabetic mice treated with 400 mg/kg of the hydro-alcoholic extract of R. coriaria seeds recovered from these reductions (p＜0.05). Further, glibenclamide alleviated hormonal and sperm count depletion in diabetes-induced mice (p＜0.05).
Conclusions: The present results indicated that the hydro-alcoholic extract of R. coriaria seeds has anti-infertility effects in diabetic males. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001938292 | oai_dc | Primary Androgen Deprivation Therapy for Prostate Cancer in Koreans: A Retrospective Multicenter Study | Primary Androgen Deprivation Therapy for Prostate Cancer in Koreans: A Retrospective Multicenter Study | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"서원익(인제대학교); 강필문(인제대학교); 김태효(동아대학교); 문경현(울산대학교); 정재민(고신대학교); 이동현(이화여자대학교); Isaac Yi Kim(The State University of New Jersey); 민권식(인제대학교); 정재일(인제대학교); 김완석(인제대학교); 강동일(인제대학교)"
] | Purpose: To evaluate the characteristics of patients who received primary androgen deprivation therapy (PADT) for prostate cancer and the clinical efficacy of this treatment.
Materials and Methods: Two hundred forty patients treated by PADT were reviewed. These patients could not receive definitive therapy owing to old age, patient need, and medical comorbidity. The patients were divided into three groups according to the extent of prostate cancer: localized, locally advanced, and metastatic. Then, prostate-specific antigen (PSA) progression in these groups was analyzed.
Results: The median age of the patients was 73.0 years, and the median pretreatment PSA level was 47.0 ng/mL. Of the patients, 91.7% were treated with combined androgen blockade, and 8.3% were treated with monotherapy. Clinical factors for PSA progression were a PSA nadir and a high clinical stage. Estimated PSA recurrence-free median survival time in each group was 57, 24, and 12 months, respectively. A PSA nadir of ＞0.2 ng/mL and metastatic stage were independent factors for expecting a poor response to PADT (hazard ratio 4.26, p＜0.001; and 2.60, p＜0.001).
Conclusions: Patients with localized or locally advanced prostate cancer who did not receive definitive therapy had lower PSA progression rates than those at metastatic stage during PADT. Further, a PSA nadir of ≤0.2 ng/mL showed better progression-free survival. Therefore, PADT can be another therapeutic option in well-selected patients with localized or locally advanced prostate cancer and PSA change should be checked carefully. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001938293 | oai_dc | Meta-Analysis of the Relationship between CXCR4 Expression and Metastasis in Prostate Cancer | Meta-Analysis of the Relationship between CXCR4 Expression and Metastasis in Prostate Cancer | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이주용(연세대학교 의과대학); 강동혁(양평건강센터); 정두용(연세대학교); 권종규(연세대학교); 이형민(질병관리본부); 조남훈(연세대학교); 최영득(연세대학교); 홍성준(연세대학교); 조강수(연세대학교)"
] | Purpose: Experimental studies have suggested that the stromal-derived factor-1 (SDF-1)/CXCR4 axis is associated with tumor aggressiveness and metastasis in several malignancies. We performed a meta-analysis to elucidate the relationship between CXCR4 expression and the clinicopathological features of prostate cancer.
Materials and Methods: Data were collected from studies comparing Gleason score, T stage, and the presence of metastasis with CXCR4 levels in human prostate cancer samples. The studies were pooled, and the odds ratio (OR) of CXCR4 expression for clinical and pathological variables was calculated.
Results: Five articles were eligible for the current meta-analysis. We found no relationship between CXCR4 expression and Gleason score (＜7 vs. ≥7). The forest plot using the fixed-effects model indicated an OR of 1.585 (95% confidence interval [CI]: 0.793∼3.171; p=0.193). Further, CXCR4 expression was not associated with the T stage (＜T3 vs. ≥T3), and the relevant meta-analysis showed OR=1.803 (95% CI: 0.756∼4.297, p=0.183). However, increased CXCR4 expression was strongly associated with metastatic disease with a fixed-effects pooled OR of 7.459 (95% CI: 2.665∼20.878, p＜0.001).
Conclusions: Our meta-analysis showed that the higher CXCR4 protein expression in prostate cancer specimens is significantly associated with the presence of metastatic disease. This supports previous experimental data supporting the role played by the SDF-1/CXCR4 axis in metastasis. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001938294 | oai_dc | Effects of Exendin-4 on Male Reproductive Parameters of D-Galactose Induced Aging Mouse Model | Effects of Exendin-4 on Male Reproductive Parameters of D-Galactose Induced Aging Mouse Model | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Akram Ahangarpour(Ahvaz Jundishapur University); Ali Akbar Oroojan(Ahvaz Jundishapur University); Hamid Heidari(Qom University of Medical Sciences)"
] | Purpose: The purpose of this study was to evaluate the role of exendin-4 on reproductive alteration in a D-galactose-induced aging mouse model.
Materials and Methods: In this experimental study, 72 male Naval Medical Research Institute mice (20∼25 g) were randomly divided into six groups: control, exendin-4 (1 nmol/kg), exendin-4 (10 nmol/kg), D-galactose (500 mg/kg), D-galactose+ exendin-4 (1 nmol/kg), and D-galactose+exendin-4 (10 nmol/kg). The aging model animals were gavaged with D-galactose for six weeks, and exendin-4 was injected intraperitoneally in the last 10 days. At the end of treatment serum luteinizing hormone (LH), follicle-stimulating hormone (FSH) and testosterone levels were evaluated and the cauda epididymis and testis were removed to analyze the sperm count and testis morphology.
Results: The testis weight and volume decreased in the D-galactose group (p＜0.01 and p＜0.05) respectively. Exendin-4 (1, 10 nmol/kg) increased these parameters in the normal and aging mouse models. Serum LH and FSH levels increased and the sperm count decreased in the D-galactose group (p＜0.05). Further, exendin-4 (1 nmol/kg) decreased LH and FSH levels and increased the serum testosterone level and sperm count in both normal and aging animals.
Conclusions: D-galactose can induce aging alternations in the male reproductive system such as decreased sperm count and increased serum LH and FSH levels through reactive oxygen species over production and reduced antioxidant enzyme activity. Further, co-administration of exendin-4 reduced reproductive complications of D-galactose in an aging mouse model. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001938295 | oai_dc | Diagnosis of a Gastrointestinal Stromal Tumor Presenting as a Prostatic Mass: A Case Report | Diagnosis of a Gastrointestinal Stromal Tumor Presenting as a Prostatic Mass: A Case Report | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"허정식(제주대학교); 박경기(제주대학교); 김영주(제주대학교); 김성대(제주대학교)"
] | Gastrointestinal stromal tumors (GISTs) are an unusual and heterogeneous group of spindle cell tumors that can also appear on the exterior of the gastrointestinal tract (extra-GISTs). Despite the fact that extra-GISTs or large rectal GISTs can lead to the clinical impression of a prostatic mass, these tumors are, in general, excluded in the differential diagnosis of spindle cell tumors observed on prostate needle biopsy. Here, we present, in detail, a case of an extra-GIST identified on prostatic biopsy; the tumor was previously believed to be a primary prostatic stromal sarcoma in the differential diagnosis. Every investigator should check for KIT (CD117) in immunohistochemical staining to rule out an extra-GIST prior to diagnosing a solitary prostatic tumor, specialized prostatic stromal tumor, or leiomyosarcoma on prostate needle biopsy. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001938296 | oai_dc | An Unexpected Course after Simultaneous Urethral Repair and Reimplantation of Penile Prosthesis in a Patient with a Urethral Stricture | An Unexpected Course after Simultaneous Urethral Repair and Reimplantation of Penile Prosthesis in a Patient with a Urethral Stricture | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"신유섭(전북대학교); 고오석(전북대학교병원); Li Tao Zhang(전북대학교); Chen Zhao(Shanghai Jiao Tong University); 박종관(전북대학교)"
] | We experienced the growth of urethral hair along the urethral stricture six years after simultaneous urethral repair and reimplantation of penile prosthesis (RPP) in a patient with a urethral stricture. We detected hair in the urethra with a stricture on the bulbous urethra. Further, we performed hair removal by using a pair of cystoscopic forceps and internal urethrotomy. Then, we performed RPP, and the patient voided well; the prosthesis worked very well and without any complications. One-stage urethroplasty with a pedicle island of the penile skin and RPP in a simultaneous stage may be an option for treating the long-segment urethral stricture in the penile prosthesis patient. However, we should pay attention to the urethral hair growth that can occur after urethral repair performed using a skin graft. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001938287 | oai_dc | Understanding the Role of Heat Shock Protein Isoforms in Male Fertility, Aging and Apoptosis | Understanding the Role of Heat Shock Protein Isoforms in Male Fertility, Aging and Apoptosis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Kaveri Purandhar(Nirma University); Prasant Kumar Jena(Nirma University); Bhumika Prajapati(Nirma University); Parth Rajput(Nirma University); Sriram Seshadri(Nirma University)"
] | Heat shock proteins (HSPs) play a role in the homeostasis, apoptosis regulation and the maintenance of the various other physiological processes. Aging is accompanied by a decrease in the resistance to environmental stress, while mitochondria are primary targets in the process of aging, their expression decreasing with age. Mitochondrion also plays a significant role in the process of spermatogenesis. HSPs have been shown to be involved in apoptosis with some of acting as apoptotic inhibitors and are involved in cytoprotection. In this review we discuss the roles of Hsp 27, 60, 70, and 90 in aging and male infertility and have concluded that these particular HSPs can be used as a molecular markers for mitochondrially- mediated apoptosis, aging and male infertility. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001938288 | oai_dc | Efficacy of Long-Term Daily Dosage of Alfuzosin 10 mg upon Sexual Function of Benign Prostatic Hypertrophy Patients: Two-Year Prospective Observational Study | Efficacy of Long-Term Daily Dosage of Alfuzosin 10 mg upon Sexual Function of Benign Prostatic Hypertrophy Patients: Two-Year Prospective Observational Study | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"윤솔(경상대학교); 현재석(경상대학교); 최재휘(경상대학교); 이성현(경상대학교); 최세민(경상대학교); 제성욱(경상대학교); 감성철(경상대학교); 화정석(경상대학교); 정기현(경상대학교)"
] | Purpose: To identify sexual function improvement associated with alfuzosin (10 mg daily for 2 years).
Materials and Methods: We enrolled 30 men with lower urinary tract symptom (LUTS) who visited Gyeongsang National University Hospital between 2010 and 2012. At first visit, urinalysis, prostate specific antigen, transrectal ultrasound, and uroflowmetry were performed. The nternational Prostate Symptom Score (IPSS), quality of life (QoL), International Index of Erectile Function (IIEF), and Male Sexual Health Questionnaire Ejaculation Function Domain (MSHQ-EjFD) questionnaires were administered, and the subjects answered the same questionnaires at 1 month, 6 months, 1 year, and 2 years of follow-up.
Results: Twelve men completed of the entire study. After administration of alfuzosin, the median IPSS at first visit, 1 month, 6 months, 1 year, and 2 years was 18.00 (interquatile range [IQR]: 14.00∼29.75), 20.00 (IQR: 11.50∼30.00), 15.50 (IQR: 8.50∼25.25), 14.50 (IQR: 9.25∼19.50), and 11.50 (IQR: 5.00∼17.75), respectively, which showed an improvement. The median QoL at the same times was 4.50 (IQR: 4.00∼5.00), 4.50 (IQR: 4.00∼5.00), 3.00 (IQR: 2.00∼4.00), 3.50 (IQR: 2.25∼4.00), and 3.00 (IQR: 1.00∼3.00), respectively, and also showed improvement. Likewise, the median IIEF was 36.50 (IQR: 24.50∼46.75), 37.50 (IQR: 26.75∼47.25), 45.50 (IQR: 35.00∼59.75), 48.50 (IQR: 34.75∼62.75), and 47.50 (IQR: 43.25∼61.00), while the median MSHQ-EjFD was 19.00 (IQR: 12.0∼24.75), 19.50 (IQR: 13.50∼27.75), 23.00 (IQR: 19.25∼32.25), 26.50 (IQR: 18.25∼34.50), 27.00 (IQR: 21.50∼32.50), respectively, with both showing improvement.
Conclusions: After administration of alfuzosin (10 mg daily for 2 years), the IPSS, QoL, IIEF, and MSHQ-EjFD all improved significantly. This means long-term administration of 10 mg of alfuzosin daily would be effective not only for LUTS but also erectile function and ejaculation. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001938289 | oai_dc | Relationship between Serum Testosterone and Cardiovascular Disease Risk Determined Using the Framingham Risk Score in Male Patients with Sexual Dysfunction | Relationship between Serum Testosterone and Cardiovascular Disease Risk Determined Using the Framingham Risk Score in Male Patients with Sexual Dysfunction | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이완철(한림대학교); 양대열(한림대학교); 김마태(한림대학교); 고경태(한림대학교); 이원기(한림대학교); 김성용(한림대학교); 김하영(한림대학교)"
] | Purpose: The aim of the present study aimed to evaluate the effect of testosterone on cardiovascular disease by using the Framingham Risk Score (FRS) in patients with sexual dysfunction.
Materials and Methods: A total of 308 men with sexual dysfunction were enrolled in this study. Clinical assessments included the 15-item International Index of Erectile Function (IIEF), blood pressure measurement, and clinical laboratory indexes. The FRS, which predicts the incidence rate of cardiovascular diseases in the next 10 years, was calculated on the basis of age, gender, total cholesterol, smoking status, high density lipoprotein cholesterol, and systolic blood pressure.
Results: The mean age of the 308 enrolled patients was 49.42±10.73 years, and the patients’ mean body mass index (kg/m2) was 25.07±3.14. The mean total IIEF score was 28.44±18.06. The median total testosterone concentration was 3.2 ng/mL (interquartile range [IQR]: 2.3∼3.2 ng/mL). The median calculated free and bioavailable testosterone concentrations were 0.052 ng/mL (IQR 0.039∼0.070 ng/mL) and 1.30 ng/mL (IQR: 1.00∼1.76 ng/mL), respectively. The mean FRS was 10.47±6.45. The FRS tended to show a negative correlation with the total and calculated free testosterone levels, but this was not significant (p=0.064 and p=0.074, respectively). In the multiple linear regression analysis, a significant negative correlation was observed between the total testosterone level and the FRS (p=0.048).
Conclusions: The results suggest that the testosterone level is related to the FRS and that a high testosterone level may decrease the risk of cardiovascular disease. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001901102 | oai_dc | Do Cigarette Smoking and Obesity Affect Semen Abnormality in Idiopathic Infertile Males? | Do Cigarette Smoking and Obesity Affect Semen Abnormality in Idiopathic Infertile Males? | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"이희대(관동대학교); 이효석(관동대학교); 이중식(가톨릭관동대학교); 박용석((의)제일의료재단제일병원); 서주태(가톨릭관동대학교)"
] | Purpose: This study was conducted to find the relative risk of semen abnormality with respect to smoking history and obesity. Materials and Methods: Subfertile or infertile men were enrolled in this study from July 2010 to June 2011. All participants provided their cigarette use information, self-reported weight, height, semen analysis, physical examination, and sexually transmitted disease status. None of the enrolled patients had any specific pathological reason for infertility. Semen abnormality was defined as a condition in which one or more parameters did not satisfy the World Health Organization’s criteria. Results: A total of 1,073 male patients were considered for this study. After the application of the inclusion criteria, 193 patients were finally analyzed. These patients were divided into two groups according to semen abnormality: the normal semen group (n=72) and the abnormal semen group (n=121). Baseline characteristics, except age and smoking history, were not significantly different between the two groups. Smoking history and age were risk factors for the semen abnormality of idiopathic infertile male patients. Conclusions: Smoking and old age were risk factors for semen abnormality. However, obesity did not affect the semen abnormality. Smoking affected semen quality and is therefore expected to play a negative role in conception. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001901104 | oai_dc | Clinical Characteristics and Treatment of Cryptorchidism in Adults: A Single Center Experience | Clinical Characteristics and Treatment of Cryptorchidism in Adults: A Single Center Experience | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"정승찬(부산대학교); 이승수(양산부산대학교병원); 구자윤(부산대학교); 이상돈(부산대학교)"
] | Purpose: We evaluated the clinical and therapeutic characteristics of adult cryptorchidism, which have been difficult to establish, given the small number of patients presenting to outpatient clinics.Materials and Methods: A retrospective study of 20 adult patients with cryptorchid testis was performed. We analyzed their palpation of testis, location, surgical method, marital status, number of children, histologic findings, and semen analysis.Results: In 17 cases with unilateral cryptorchidism, the mean age at surgery was 31.1±12.5 years. Fourteen patients had a palpable, small cryptorchid testis. The location of the testis, as verified, was inguinal in 14, prepubic in 2, and intra-abdominal in 1, respectively. We performed orchiopexy in 14 out of 15 patients who sought to have this procedure. Four among 6 married patients had children. Testis biopsy was performed in 12 patients, and all showed abnormal histologic findings. Three among 4 patients, performed semen analysis, showed abnormal findings. In three cases of bilateral cryptorchidism, the mean age at surgery was 35.7±12.5 years. All of these patients had palpated cryptorchid testes in the inguinal area and sought to have a bilateral orchiopexy. Two patients have been married but had no children. All showed abnormal findings in both testis biopsy and semen analysis. No testicular neoplasm was detected during the duration of follow-up.Conclusions: Most adult patients with cryptorchidism preferred orchiopexy to orchiectomy. However, most of patients showed abnormal histology of the testis and semen analysis. Therefore, orchiopexy with regular scrotal examination may be considered a suitable treatment options for adult cryptorchidism. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001901106 | oai_dc | Perirenal Lymphangiomatosis | Perirenal Lymphangiomatosis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"전태경(부산대학교병원); 공도훈(부산대학교); 박현준(부산대학교); 김석(부산대학교); 박원영(부산대학교); 김수동(동아대학교); 하홍구(부산대학교)"
] | Lymphangioma is a rare, benign mesenchymal neoplasm, which is characterized by numerous intercommunicating cystic spaces containing lymphatic fluid. It is considered a congenital disease resulting from the obstruction of regional lymph drainage during the developmental period. Lymphangioma may be focal/unilateral or diffuse/bilateral, and in the latter case, it is referred to as lymphangiomatosis. Here, we report a case of a 38-year-old man with perirenal lymphangiomatosis. The patient’s chief complaint was left flank pain, and left pleural effusion was found on radiological examination. After radical nephrectomy, the pathological examinations revealed that the kidney was enclosed by a multicystic mass with intrarenal cystic dilatations. We report the case and discuss the management of perirenal lymphangiomatosis with a literature review. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001901108 | oai_dc | Successful Removal of an Intravesical Electrical Wire Cable | Successful Removal of an Intravesical Electrical Wire Cable | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"안현수(서울대학교병원 비뇨기과); 손환철(서울대학교)"
] | A few previous reports have described cases wherein electrical wire cables were inserted into the male urethra and bladder. Electrical wire cables are available at home and are easy to insert. However, after they coil in the patient’s bladder, they are difficult to remove. In February 2013, a 30-year-old man presented to the emergency room of SMG-SNU Boramae Medical Center with a urethral foreign body. He had inserted an electrical wire cable into his urethra for the purpose of masturbation, despite having a regular sex partner and no underlying disease. A kidney-ureter-bladder radiography showed a tangled wire in his bladder and urethra. On the next day, we tried to remove the wire cystoscopically, but this proved to be impossible because of complex coiling and the slippery surface of the wire. A Pfannenstiel incision was made to remove the foreign body. No postoperative complications were noted. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001901083 | oai_dc | The Prescribing and Dispensing of Phosphodiesterase Type 5 Inhibitors in South Korea: A Questionnaire Survey of Patient Discomfort | The Prescribing and Dispensing of Phosphodiesterase Type 5 Inhibitors in South Korea: A Questionnaire Survey of Patient Discomfort | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김상우(고려대학교); 김종욱(고려대학교); 채지윤(고려대학교); 김진욱(중앙대학교); 윤철용(연세대학교); 오미미(고려대학교); 박홍석(고려대학교); 김제종(고려대학교); 문두건(고려대학교)"
] | Purpose: This study was performed to investigate the discomfort reported by patients taking phosphodiesterase type 5 inhibitors (PDE5Is) in clinical practice. Materials and Methods: From September 2011 to March 2012, we surveyed patients who were prescribed PDE5Is for erectile dysfunction (ED). The questionnaire elicited information concerning: patient characteristics, medication counseling received and inconveniences experienced in hospitals and at pharmacies, effects of PDE5Is, and the separation of the prescribing and the dispensing of PDE5Is. Results: A total of 237 patients completed the questionnaire (mean age: 58.81±9.14 years). Among the 62 patients (26.0%) who reported having encountered some inconveniences in hospitals, the most frequently expressed concerns ’assistant staff,’ including nurses (38.7%), ‘testing procedures’ (27.4%), and ‘the issuing of prescriptions’ (22.6%). Of the 137 patients (57.8%) who noted inconveniences in obtaining medications from pharmacies, 60.6% cited ‘self-consciousness’ as the most common reason, followed by ‘insufficient medication counseling’ (22.6%), and ‘absence of consultation’ (11.6%). In contrast, 82% of the patients were satisfied with the medication counseling that they had received in hospitals, covering drug usage, side effects, and precautions regarding PDE5Is; this proportion was only 30% for pharmacies. Further, most patients (89%) indicated that they preferred to obtain their prescriptions and medications for ED from the hospital at the same time.Conclusions: Treatment of ED is a highly private matter. According to the survey, ED patients more often felt that obtaining medication from pharmacies was inconvenient. The sociocultural aspects of ED necessitate that exceptions to separating the prescribing and the dispensing of medication be considered. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001901084 | oai_dc | A Milk Protein, Casein, as a Proliferation Promoting Factor in Prostate Cancer Cells | A Milk Protein, Casein, as a Proliferation Promoting Factor in Prostate Cancer Cells | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박성우(양산부산대학교병원); 김주영(양산부산대학교병원); 김유선(아주대학교); 이상진(국립암센터); 이상돈(양산부산대학교병원); 정문기(양산부산대학교병원)"
] | Purpose: Despite most epidemiologic studies reporting that an increase in milk intake affects the growth of prostate cancer, the results of experimental studies are not consistent. In this study, we investigated the proliferation of prostate cancer cells treated with casein, the main protein in milk.Materials and Methods: Prostate cancer cells (LNCaP and PC3), lung cancer cells (A459), stomach cancer cells (SNU484), breast cancer cells (MCF7), immortalized human embryonic kidney cells (HEK293), and immortalized normal prostate cells (RWPE1) were treated with either 0.1 or 1 mg/mL of α-casein and total casein extracted from bovine milk. Treatments were carried out in serum-free media for 72 hours. The proliferation of each cell line was evaluated by an 3-(4,5-Dimethyl-thiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Results: α-Casein and total casein did not affect the proliferations of RWPE1, HEK293, A459, SNU484, MCF7, HEK293, or RWPE1 cells. However, PC3 cells treated with 1 mg/mL of α-casein and casein showed increased proliferation (228% and 166%, respectively), and the proliferation of LNCaP cells was also enhanced by 134% and 142%, respectively. The proliferation mechanism of α-casein in PC3 and LNCaP cells did not appear to be related to the induction of Insulin-like growth factor-1 (IGF-1), since the level of IGF-1 did not change upon the supplementation of casein.Conclusions: The milk protein, casein, promotes the proliferation of prostate cancer cells such as PC3 and LNCaP. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001901085 | oai_dc | Induction of Contraception by Intraepididymal Sclerotherapy | Induction of Contraception by Intraepididymal Sclerotherapy | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박형근(건국대학교); 백성현(건국대학교); 김형곤(건국대학교); 노용수(건국대학교); 배상락(가톨릭대학교)"
] | Purpose: The objective of the present study was to evaluate the efficacy of a sclerosing solution for inducing epididymal occlusion in male rats.Materials and Methods: Male Sprague-Dawley rats were divided into two groups: an injection group (n=20) and control group (n=20). Before injecting the sclerosing agent, seminal vesiculectomy and sperm identification using electrostimulation were performed in all of the rats. In the injection group, 0.2 mL of 0.1% sodium tetradecyl sulfate solution was injected into the epididymis. In the sham group, only the identification of the epididymis was performed. At 4 and 12 weeks after the injection, semen was collected by electrostimulation and evaluated to assess the contraceptive effect. Epididymis was evaluated by hematoxylin and eosin (H&E) staining.Results: After 4 and 12 weeks, semen collection was performed in the two groups. Sperms were not observed in the injection group, while there was no change in the sperms in the sham group. H&E staining showed the obstruction of epididymal tubules and an accumulation of inflammatory cells in the injection group.Conclusions: This study showed that the sclerosing agent induced sterilization in male rats. This result suggests that the injection method can replace vasectomy as a contraceptive method. However, a further study of large animals and a clinical study are needed. Further, the long-term effectiveness of this method needs to be studied. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001901086 | oai_dc | Surgical Outcome of Urethroplasty Using Penile Circular Fasciocutaneous Flap for Anterior Urethral Stricture | Surgical Outcome of Urethroplasty Using Penile Circular Fasciocutaneous Flap for Anterior Urethral Stricture | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김경록(서울대학교); 서준교(서울대학교); 백재승(서울대학교); 김수웅(서울대학교)"
] | Purpose: Penile circular fasciocutaneous flap urethroplasty is a useful technique for a long anterior urethral stricture due to the flap’s hairless nature and ample length. We investigated the surgical outcomes of urethroplasty for a complex anterior urethral stricture, performed using a penile circular fasciocutaneous flap.Materials and Methods: Between 2008 and 2013, we performed a retrospective review of 29 patients who underwent urethroplasty using a penile circular fasciocutaneous flap and had at least 6 months of follow-up. A total of 20 cases utilized only a fasciocutaneous flap, while 9 cases combined a fasciocutaneous flap with other surgery. Success was defined as no requirement of additional urethral instrumentation.Results: The overall success rate was 68.9% (20 out of 29 cases) at a median follow-up of 19 months. Furthermore, fasciocutaneous flap urethroplasty rendered the actual stricture-free rate of 79.3%. The location of recurrence was mostly at the junction of the flap. Among 9 surgical failures, 5 cases were treated successfully by using an additional surgical procedure. Fistula repair was needed in 1 case 4 months later. Further, periodic urethral dilation was performed in the remaining 3 cases. The failure rate was significantly higher in patients with suprapubic cystostomy than in patients without suprapubic cystostomy. The most common complication was post-micturition dribbling.Conclusions: Penile circular fasciocutaneous flap urethroplasty is a useful method for the reconstruction of a long anterior urethral stricture. A sufficient healthy margin should be acquired for better surgical results due to the fact that most recurrence occurs at the junction of the flap. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001901088 | oai_dc | Magnification-Assisted Subinguinal Varicocelectomy with Testicular Delivery in Children: A Preliminary Report | Magnification-Assisted Subinguinal Varicocelectomy with Testicular Delivery in Children: A Preliminary Report | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"조석주(제주대학교); 김성철(인제대학교해원대백병원 비뇨기과); 김건석(울산대학교); 박성찬(울산대학교)"
] | Purpose: To evaluate the effectiveness of magnification-assisted subinguinal varicocelectomy (MASV) with testicular delivery in children with severe varicocele.Materials and Methods: We retrospectively analyzed the clinical data of 23 children 15 years or younger (mean age, 12.3±1.8 years) who underwent MASV with testicular delivery and ligation of all collateral veins except arteries and deferential veins between January 2010 and January 2014. All patients had grade 3 varicocele on the left side. Varicocelectomy was decided upon due to scrotal hypotrophy (n=14, 60.9%), the existence of mass (n=6, 26.1%, including 1 recurrent case), and discomfort (n=3, 13.0%). The preservation of internal spermatic artery (ISA) was successful in 8 patients (34.8%). The mean follow-up time was 10.8±6.6 months.Results: The surgical success rate of varicocelectomy was 100%. The overall symptom resolution rate was 91.3%. The scrotal mass and discomfort disappeared, but testicular catch-up growth did not occur in 2 among 14 patients with scrotal hypotrophy. The left testis volume increased from 6.5±4.3 mL to 10.6±7.5 mL (p=0.003). There were no significant inter-group differences in terms of the surgical success rate, symptom resolution, and catch-up growth between the ISA preservation group and the ligation group. None of the subjects demonstrated testicular atrophy or hydrocele after surgery.Conclusions: MASV with testicular delivery is an effective and safe method for children with severe varicocele. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART001901100 | oai_dc | Effects of Tamsulosin on Premature Ejaculation in Men with Benign Prostatic Hyperplasia | Effects of Tamsulosin on Premature Ejaculation in Men with Benign Prostatic Hyperplasia | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"최재휘(경상대학교); 화정석(경상대학교); 감성철(경상대학교); 제성욱(경상대학교); 현재석(경상대학교)"
] | Purpose: Previous studies have revealed that tamsulosin is effective in improving lower urinary tract symptoms (LUTS) and erectile functioning but has some inhibitory effects on ejaculation, including decreased ejaculatory volume. However, these inhibitory effects on ejaculation can be beneficial to patients with premature ejaculation (PE). Therefore, this study was conducted to understand the effect of tamsulosin on PE in men with benign prostatic hyperplasia.Materials and Methods: Twenty-nine patients who visited with LUTS were categorized into 2 groups of LUTS-only patients (n=12) and LUTS combined with PE (LUTS+PE) patients (n=17), and 0.4 mg of tamsulosin was administered to the patients of both groups for 12 weeks. Comparative analyses of before and after the treatment were conducted for calculating the International Prostate Symptom Score (IPSS), International Index of Erectile Function-5 (IIEF-5), intravaginal ejaculatory latency time (IELT), premature ejaculation diagnostic tool (PEDT), and premature ejaculation profile (PEP). The patients with an IPSS score of 8 or higher were determined as LUTS patients, and the patients with IELT of less than 2 minutess and a PEDT score of 9 or higher were determined as PE patients.Results: After treatment, the IPSS score significantly decreased in both groups. There was no statistically significant change in the PEDT for the LUTS group, but there was a significant decrease in PEDT (p=0.012; from 12.1±3.31 to 8.4±4.49) in the LUTS+PE group.Conclusions: Tamsulosin not only has a treatment effect for LUTS but also improves the PE of LUTS+PE patients. Therefore, further studies are needed to confirm the effects of tamsulosin on PE. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057457 | oai_dc | The Practicality of Targeted Prostate Biopsy Procedures on the Dominant Side of the Tumor Determined by Magnetic Resonance Imaging in Elderly Patients with High Serum Levels of Prostate-Specific Antigen | The Practicality of Targeted Prostate Biopsy Procedures on the Dominant Side of the Tumor Determined by Magnetic Resonance Imaging in Elderly Patients with High Serum Levels of Prostate-Specific Antigen | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Jung Sik Huh(Jeju National University); Bong Soo Kim(Jeju National University); Young Joo Kim(Jeju National University); Sung Dae Kim(Jeju National University); Kyung Kgi Park(Jeju National University)"
] | Purpose: To examine the possibility of reducing the number of cores per prostate biopsy in elderly patients with high levels of prostate-specific antigen (PSA) without significantly lowering the detection rate of prostate cancer.Materials and Methods: Two hundreds sixteen men with PSA levels ＞20 ng/mL who underwent prostate biopsies from May 2009 to April 2013 were retrospectively reviewed. With the help of magnetic resonance imaging (MRI), the laterality of the domi-nant tumor burden in patients was determined. The results of targeted biopsies were compared with those of conventional biopsy procedures.Results: The mean age and PSA level were 79.5 years and 81.3 ng/mL, respectively, and the overall diagnostic rate of sextant biop-sies was 81.9% (177/216). MRI was able to show the tumor burden in 189 of the 216 patients. The detection rate of transrectal ultrasonography (TRUS)-guided targeted biopsies was 87.3% (165/189). Detection rates were comparable with conventional bi-opsies (81.9% [177/216]) (p=0.23). Of the 177 men in whom the results of the sextant biopsy were positive, 12 men (6.8%) with PSA levels ＜29 ng/mL did not have any cancer cells according to targeted biopsies. However, all other patients were diagnosed with prostate cancer using the abovementioned techniques.Conclusions: We believe that TRUS-guided targeted biopsies of the prostate in elderly men with high PSA levels could reduce the number of unnecessary cores per biopsy. However, a risk of detection loss remains. Therefore, we recommend that at least a sextant biopsy should be performed, even in elderly patients, in order to detect prostate cancer. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057458 | oai_dc | Changes in Nocturia and Lower Urinary Tract Symptoms after Radical Prostatectomy | Changes in Nocturia and Lower Urinary Tract Symptoms after Radical Prostatectomy | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Kyung Jae Hur(The Catholic University of Korea); Kyu Won Lee(The Catholic University of Korea); Su Jin Kim(The Catholic University of Korea); Kang Sup Kim(The Catholic University of Korea); 배웅진(가톨릭대학교); Hyuck Jin Cho(The Catholic University of Korea); Sung Hoo Hong(The Catholic University of Korea); Ji Youl Lee(Th... | Purpose: The goal of this study was to evaluate changes in nocturia and other lower urinary tract symptoms (LUTS) after laparoscopic radical prostatectomy (LRP) and robot-assisted laparoscopic radical prostatectomy (RALP).Materials and Methods: We reviewed the medical records of 96 patients who underwent LRP or RALP for clinically localized prostate cancer and completed the International Prostate Symptom Score (IPSS) questionnaire, which provided a basis for assessing their symptoms. We also evaluated maximal flow rate and post-void residual urine volume over a follow-up period of at least 24 months. We divided the patients into three groups according to postoperative changes in the frequency of nocturia.Results: Voiding symptoms significantly improved over the course of 24 months in patients who underwent LRP or RALP. However, most patients showed persistent or increased nocturia after LRP or RALP. Moreover, more than one third of the patients (33/96) presented with exacerbated nocturia (1.0±0.9 episodes of preoperative nocturia vs. 3.0±1.3 episodes of postoperative nocturia). Multiple regression analysis showed that preoperative IPSS storage sub-score had negative association with the nocturia after radical prostatectomy (p=0.005). However, patients’ age, body mass index, preoperative prostate specific antigen, Gleason score, T-stage, and prostate volume had no association.Conclusions: The present study showed that nocturia was influenced by a range of factors, including other storage LUTS and the relief of bladder outlet obstruction after radical prostatectomy. Moreover, the preoperative storage symptoms are regarded as an important factor which influences the changes of nocturia after radical prostatectomy. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057459 | oai_dc | Long-Term Safety and Longevity of a Mixture of Polymethyl Methacrylate and Cross-Linked Dextran (Lipen-10Ⓡ) after Penile Augmentation: Extension Study from Six to 18 Months of Follow-Up | Long-Term Safety and Longevity of a Mixture of Polymethyl Methacrylate and Cross-Linked Dextran (Lipen-10Ⓡ) after Penile Augmentation: Extension Study from Six to 18 Months of Follow-Up | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Ma Tae Kim(Hallym University Kangdong Sacred Heart Hospital); 고경태(독립연구자); 이원기(한림대학교); Sae Chul Kim(Chung-Ang University Hospital); 양대열(한림대학교)"
] | Purpose: The goal of this study was to investigate the long-term efficacy and safety of a mixture of polymethyl methacrylate (PMMA) and cross-linked dextran Lipen-10Ⓡ used for penile augmentation under the physical impact generated during sexual intercourse.Materials and Methods: From March 2010 to October 2011, a total of 20 patients with a mean age of 44 years (interquartile range, 20∼70 years) who requested penile augmentation participated in this study. Lipen-10Ⓡ filler is a mixture of 75% cross-linked dextran, 15% PMMA, and 10% hypromellose solution. With the patient in the supine position, Lipen-10Ⓡ was injected into the subcutaneous tissue between the dartos fascia and Buck’s fascia of the penis using a fanning technique. Penile length and circumference were measured before the procedure and six, 12, and 18 months after the procedure. Values were compared using the Student’s t-test and the paired t-test.Results: A total of 15 patients completed this study. The increases in circumference and length observed six months after the procedure were found to have been maintained without change at 12 and 18 months of follow-up. At 12 and 18 months of follow-up, no abnormal findings were observed. Pelvic magnetic resonance imaging conducted at 18 months of follow-up showed no trace of the injected filler having migrated to other sites, and the volume was well maintained.Conclusions: Lipen-10Ⓡ, a mixture of PMMA and cross-linked dextran, showed good durability and tolerability over 18 months of follow-up during which the participants were sexually active. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057460 | oai_dc | Impaired Physical Performance and Clinical Responses after a Recreational Bodybuilder’s Self-Administration of Steroids: A Case Report | Impaired Physical Performance and Clinical Responses after a Recreational Bodybuilder’s Self-Administration of Steroids: A Case Report | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Katherine Veras(University of São Paulo, São Paulo, Brazil); Fernando Lopes Silva-Junior(University of São Paulo, São Paulo, Brazil); Adriano Eduardo Lima-Silva(Federal University of Pernambuco, Recife, Brazil); Fernando Roberto De-Oliveira(Federal University of Lavras, Lavras, Brazil); Flávio Oliveira Pires(Unive... | We reported clinical and physical responses to 7 weeks of anabolic-androgenic steroid (AAS) self-administration in a male recreational bodybuilder. He was self-administrating a total of 3,250 mg of testosterone when his previous and current clinical and physical trials records were revisited. Body shape, performance, and biochemistry results were clustered into three phases labeled PRE (before the self-use), POST I (immediately at the cessation of the 7-week administration), and POST II (12 weeks after the cessation). Elevated testosterone and estradiol levels were observed in the POST I phase, while hepatic and renal functions remained altered in the POST II phase. Body mass and body fat percentages increased throughout the three phases. When adjusted according to body mass, drops in aerobic and anaerobic power and capacity (2.1% to 12.9%) were observed across the phases. This case report shows that overall performance decreased when a bodybuilding practitioner self-administered AAS. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057451 | oai_dc | Testosterone Replacement Therapy and Cardiovascular Risk: A Review | Testosterone Replacement Therapy and Cardiovascular Risk: A Review | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Giovanni Corona G(Maggiore-Bellaria Hospital, Bologna, Italy); Giulia Rastrelli(University of Florence, Florence, Italy); Elisa Maseroli(University of Florence, Florence, Italy); Alessandra Sforza(Maggiore-Bellaria Hospital, Bologna, Italy); Mario Maggi(University of Florence, Florence, Italy)"
] | Recent reports in the scientific and lay press have suggested that testosterone (T) replacement therapy (TRT) is likely to increase cardiovascular (CV) risk. In a final report released in 2015, the Food and Drug Administration (FDA) cautioned that prescribing T products is approved only for men who have low T levels due to primary or secondary hypogonadism resulting from problems within the testis, pituitary, or hypothalamus (e.g., genetic problems or damage from surgery, chemotherapy, or infection). In this report, the FDA emphasized that the benefits and safety of T medications have not been established for the treatment of low T levels due to aging, even if a man’s symptoms seem to be related to low T. In this paper, we reviewed the available evidence on the association between TRT and CV risk. In particular, data from randomized controlled studies and information derived from observational and pharmacoepidemiological investigations were scrutinized. The data meta-analyzed here do not support any causal role between TRT and adverse CV events. This is especially true when hypogonadism is properly diagnosed and replacement therapy is correctly performed. Elevated hematocrit represents the most common adverse event related to TRT. Hence, it is important to monitor hematocrit at regular intervals in T-treated subjects in order to avoid potentially serious adverse events. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057455 | oai_dc | Associations of Self-Reported Erectile Function with Non-Invasive Measurements of Endothelial Function: A Preliminary Study | Associations of Self-Reported Erectile Function with Non-Invasive Measurements of Endothelial Function: A Preliminary Study | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Jong Kyou Kwon(Yonsei University College of Medicine); Joo Yong Lee(Yonsei University College of Medicine); Hae Do Jung(Yonsei University College of Medicine); Cheol Kyu Oh(Inje University College of Medicine); 최영득(Yonsei University); 조강수(Yonsei University)"
] | Purpose: To evaluate the association of self-reported erectile function and endothelial function using the EndoPAT device.Materials and Methods: We prospectively enrolled 76 men (age≥40 years) after obtaining a complete medical history and a self-reported questionnaire (International Index of Erectile Function-5 [IIEF-5], SEP Q2, Q3). Endothelial function was non- invasively measured with an EndoPAT 2000, recorded as the reactive hyperemia index (RHI), and analyzed according to the patients’ baseline characteristics.Results: The mean patient age and IIEF-5 score were 62.50±8.56 years and 11.20±6.36, respectively. In comparing the RHI according to erectile dysfunction (ED) risk factors, the RHI was significantly lower in older subjects (p=0.004). There was no difference in the RHI according to age, body mass index, waist circumference, obesity, smoking habit, or other comorbidities. When the subjects were divided into four groups according to the severity of ED, no statistical differences in the RHI value were found among the groups. There was no difference in IIEF-5 according to the RHI when categorized according to the normal cutoff value or quartile ranges. The second subdomain of IIEF-5 (erection firmness) was significantly correlated with the RHI value (R=0.309, p=0.007); however, this was not the case with the other IIEF-5 subdomains. Self-assessment showed a tendency toward a negative correlation with the RHI value (R=−0.202, p=0.080).Conclusions: The role of endothelial function measurement by the EndoPAT in the evaluation and management of ED patients remains inconclusive. However, further studies are needed to validate the role of endothelial function measurement, by the EndoPAT or any other device. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057452 | oai_dc | Smoking and Male Infertility: An Evidence-Based Review | Smoking and Male Infertility: An Evidence-Based Review | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Avi Harlev(Ben-Gurion University of the Negev, Beersheba, Israel); Ashok Agarwal(Cleveland Clinic, Cleveland, OH, USA); Sezgin Ozgur Gunes(Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey); Amit Shetty(Cleveland Clinic, Cleveland, OH, USA); Stefan Simon du Plessis(Stellenbosch University, Tygerberg, So... | Many studies have reported that the contents of cigarette smoke negatively affect sperm parameters, seminal plasma, and various other fertility factors. Nevertheless, the actual effect of smoking on male fertility is not clear. The effect of smoking on semen parameters is based on the well-established biological finding that smoking increases the presence of reactive oxygen species, thereby resulting in oxidative stress (OS). OS has devastating effects on sperm parameters, such as viability and morphology, and impairs sperm function, hence reducing male fertility. However, not all studies have come to the same conclusions. This review sheds light upon the arguable association between smoking and male fertility and also assesses the impact of non-smoking routes of tobacco consumption on male infertility. It also highlights the evidence that links smoking with male infertility, including newly emerging genetic and epigenetic data, and discusses the clinical implications thereof. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057453 | oai_dc | Individualized Treatment Guidelines for Postpubertal Cryptorchidism | Individualized Treatment Guidelines for Postpubertal Cryptorchidism | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"정재민(부산대학교); 이상돈(부산대학교)"
] | Cryptorchidism is a well-known congenital anomaly in children. However, its diagnosis is often delayed for reasons including patient unawareness or denial of abnormal findings in the testis. Moreover, it has been difficult to establish an optimal treatment strategy for postpubertal cryptorchidism, given the small number of patients. Unlike cryptorchidism in children, postpubertal cryptorchidism is associated with an increased probability of neoplasms, which has led orchiectomy to be the recommended treatment. However, routine orchiectomy should be avoided in some cases due to quality-of-life issues and the potential risk of perioperative mortality. Based on a literature review, this study proposes individualized treatment guidelines for postpubertal cryptorchidism. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057454 | oai_dc | Dyslipidemia Prevalence in Iranian Adult Men: The Impact of Population-Based Screening on the Detection of Undiagnosed Patients | Dyslipidemia Prevalence in Iranian Adult Men: The Impact of Population-Based Screening on the Detection of Undiagnosed Patients | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Abolfazl Mohammadbeigi(Qom University of Medical Sciences, Qom, Iran); Esamil Moshiri(Arak University of Medical Sciences, Arak, Iran); Narges Mohammadsalehi(Qom University of Medical Sciences, Qom, Iran); Hossein Ansari(Zahedan University of Medical Sciences, Zahedan, Iran); Ali Ahmadi(Shahrekord University of Me... | Purpose: Dyslipidemia has been established as one of the most important modifiable risk factors for cardiovascular disease. Due to the higher prevalence of dyslipidemia in males, this study aimed to estimate the prevalence of dyslipidemia in Iranian urban men.Materials and Methods: A screening program was conducted in 845 Iranian men 25 years of age and older in 2014. A health interview survey was conducted to evaluate the prevalence of self-reported dyslipidemia and to collect demographic data, as well as serum lipid profile screening by a reference laboratory. Lipoprotein levels was categorized based on the Adult Treatment Panel III criteria and the data were analyzed using the chi-square test and analysis of variance.Results: The overall prevalence of dyslipidemia was 51.8%, and the prevalence of various forms of dyslipidemia was as follows: hypercholesterolemia (≥240 mg/dL), 11.4%; hyper-low-density lipoprotein cholesterol (≥160 mg/dL), 9.6%; hypertriglyceri-demia (≥200 mg/dL), 25%; and hypo-high-density lipoprotein (HDL) cholesterol (＜40 mg/dL), 34.3%. With the exception of hypo-HDL, all forms of dyslipidemia were significantly less common in men over 65 years of age (p＜0.05).Conclusions: The prevalence of hypo-HDL and hypertriglyceridemia was higher than expected in Iranian adult men, with half of men 25 years of age and older affected by at least one form of dyslipidemia. A large gap in primary and secondary care was observed, because nearly 80% of patients with dyslipidemia were unaware of their status. Urgent preventive programs and lifestyle changes are necessary to reduce the prevalence of cardiovascular risk factors. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057456 | oai_dc | Preoperative Urinary Retention Increased the Risk of Urinary Retention after Photoselective Vaporization of the Prostate | Preoperative Urinary Retention Increased the Risk of Urinary Retention after Photoselective Vaporization of the Prostate | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"조성용(서울특별시보라매병원); Yun Kwan Ro(Seoul National University); Hwanik Kim(SMG-SNU Boramae Medical Center); 손환철(서울대학교)"
] | Purpose: The aim of the present study was to evaluate preoperative acute urinary retention (AUR) as a factor affecting the outcomes of patients who underwent photoselective vaporization of the prostate (PVP), both in terms of overall effectiveness and the postoperative incidence of AUR.Materials and Methods: Baseline prostate characteristics were obtained for patients who underwent PVP, including prostate- specific antigen (PSA) levels, transrectal ultrasound findings, voiding diary parameters, the International Prostate Symptoms Score (IPSS), and uroflowmetry parameters. These parameters were assessed two weeks, one month, three months, six months, and three years postoperatively. Subjects were divided into AUR and non-AUR groups based on the preoperative occurrence of AUR.Results: Of the 476 patients, 91 had at least one episode of preoperative AUR. The AUR group was found to be significantly older and to have significantly higher PSA levels, lower body mass indices, and larger prostates. At one year of follow-up, the total IPSS was 7.6±6.8 in the AUR group and 11.4±8.2 in the non-AUR group, with the AUR group showing a more significant improvement. In the non-AUR group, 17 of the 385 patients (4.4%) experienced postoperative retention, compared to 16 of the 91 patients (17.6%) patients in the AUR group.Conclusions: Almost all patients exhibited improvements in subjective and objective voiding parameters following PVP, regardless of the presence of preoperative urinary retention. Patients with a preoperative history of AUR had a higher risk of postoperative retention. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002057449 | oai_dc | Evolution of Phosphodiesterase-5 Inhibitors | Evolution of Phosphodiesterase-5 Inhibitors | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"문두건(고려대학교)"
] | 비뇨기과학 | null | kci_detailed_000250.xml | ||||
ART002057450 | oai_dc | Testosterone Replacement Therapy and Prostate Cancer Incidence | Testosterone Replacement Therapy and Prostate Cancer Incidence | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Michael Louis Eisenberg(Stanford University School of Medicine, Stanford, CA, USA)"
] | While early studies demonstrated a positive association between testosterone and prostate cancer, evidence on the nature of the relationship has evolved with time and newer data. Studies examining links between baseline testosterone levels as well as testosterone therapy and incident prostate cancer, reveal a more complex relationship. Moreover, investigators have reported their initial experiences with supplementing testosterone in men with a history of both treated and untreated prostate cancer. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002100962 | oai_dc | Clinical Management of Priapism: A Review | Clinical Management of Priapism: A Review | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Kazuyoshi Shigehara(Kanazawa University); Mikio Namiki(Kanazawa University)"
] | Priapism is defined as a persistent and painful erection lasting longer than four hours without sexual stimulation. Based on episode history and pathophysiology, priapism is classified into three subtypes: ischemic (low-flow), non-ischemic (high-flow), and stuttering priapism. Ischemic priapism is characterized by a persistent, painful erection with remarkable rigidity of the corpora cavernosa caused by a disorder of venous blood outflow from this tissue mass, and is similar to penile compartment syndrome. Stuttering priapism is characterized by a self-limited, recurrent, and intermittent erection, frequently occurring in patients with sickle cell disease. Non-ischemic priapism is characterized by a painless, persistent nonsexual erection that is not fully rigid and is caused by excess arterial blood flow into the corpora cavernosa. Because ischemic and non-ischemic priapism differ based on emergency status and treatment options, appropriate discrimination of each type of priapism is required to initiate adequate clinical management. The goal of management of priapism is to achieve detumescence of the persistent penile erection and to preserve erectile function after resolution of the priapism. To achieve successful management, urologists should address this emergency clinical condition. In the present article, we review the diagnosis and clinical management of the three types of priapism. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002100963 | oai_dc | Insights into an Award-Winning Summer Internship Program: The First Six Years | Insights into an Award-Winning Summer Internship Program: The First Six Years | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Anthony Kashou(Cleveland Clinic); Damayanthi Durairajanayagam(Cleveland Clinic); Ashok Agarwal(Cleveland Clinic)"
] | Since its inception in 2008, the American Center for Reproductive Medicine’s summer internship program in reproductive research and writing has trained 114 students from 23 states within the United States and 10 countries worldwide. Its fundamental goal is to inspire pre-medical and medical students to embrace a career as a physician-scientist. During this intensive course, established scientists and clinicians train interns in the essential principles and fundamental concepts of bench research and scientific writing. Over the first six years (2008∼2013), interns have collectively published 98 research articles and performed 12 bench research projects on current and emerging topics in reproductive medicine. Interns have also developed and honed valuable soft skills including time management, communication and presentation skills, as well as life values, which all enhance personal and professional satisfaction. Program graduates are able to recognize the value of medical research and its potential to impact patient care and gain insight into their own career pathway. Between 2011 and 2014, the internship program was thrice awarded a Scholarship in Teaching Award by Case Western Reserve School of Medicine for its innovative teaching approach and positive impact on medical education and student careers. This report highlights the demographics, logistics, implementation, feedback, and results of the first six years of the American Center for Reproductive Medicine’s summer internship program at Cleveland Clinic (Cleveland, OH, USA). This may be helpful to other research and academic institutions considering imple-menting a similar program. In addition, it creates awareness among potential physician-scientists of what the world of research has to offer in both scientific writing and bench research. Finally, it may stimulate further discussion regarding narrowing the gap between physicians and scientists and refinement of the current program. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002100964 | oai_dc | The Outcome of Multiple Slit on Plaque with Plication Technique for the Treatment of Peyronie’s Disease | The Outcome of Multiple Slit on Plaque with Plication Technique for the Treatment of Peyronie’s Disease | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"신수환(고려대학교); 정형국(고려대학교); 박종진(고려대학교); 채지윤(고려대학교); 김종욱(고려대학교); 오미미(고려대학교); 박홍석(고려대학교); 김제종(고려대학교); 문두건(고려대학교)"
] | Purpose: To evaluate the postoperative outcome of the multiple slit on plaque plication technique for the treatment of Peyronie’s disease.Materials and Methods: We retrospectively evaluated 22 patients who underwent plaque incision with penile plication for the surgical treatment of Peyronie’s disease, who had failed medical treatment between 2009 and 2014. Patients were grouped by preoperative degree of penile curvature into Group I: mild (n=5, 22.7%), Group II: moderate (n=11, 50.0%), and Group III: severe (n=6, 27.3%). After a thorough review of the medical records, we evaluated (a) the correction of the curvature; (b) sexual function; and (c) any penile shortening or other complications.Results: The mean postoperative follow-up period was 39 months. Complete correction of the curvature was attained in 21 patients (95.5%). As an inevitable complication, minimal penile shortening (＜1.5 cm) was reported by 14 patients (82.4%) but did not adversely affect sexual intercourse (0%), and all patients found the extent of penile shortening to be acceptable. Nineteen patients had good erectile function (International Index of Erectile Function ＞21). The most frequent complication was subcutaneous penile edema in three patients (13.6%), which was resolved within about 3 months following surgery.Conclusions: As a modified technique, multiple slit on plaque with plication is a simple, minimally-invasive and effective technique for correcting penile curvature regardless of curvature severity. The degree of penile curvature does not significantly predict the amount of penile length loss. | 비뇨기과학 | null | kci_detailed_000250.xml | |||
ART002100965 | oai_dc | Hypercholesterolemia Is Associated with a Shorter Time to Castration-Resistant Prostate Cancer in Patients Who Have Undergone Androgen Deprivation Therapy | Hypercholesterolemia Is Associated with a Shorter Time to Castration-Resistant Prostate Cancer in Patients Who Have Undergone Androgen Deprivation Therapy | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Jong Chul Jeon(Ulsan University Hospital); Jaeyoung Park(Ulsan University Hospital); Sungchan Park(Ulsan University Hospital); Kyung Hyun Moon(Ulsan University Hospital); Sang Hyeon Cheon(Ulsan University Hospital); Sejun Park(Ulsan University Hospital)"
] | Purpose: The goal of this study was to investigate the association between hypercholesterolemia and the time required for progression to castration-resistant prostate cancer (CRPC) in patients who have undergone androgen deprivation therapy (ADT).Materials and Methods: Data from 154 patients with prostate cancer between 2005 and 2012 were reviewed retrospectively. ADT was employed as a treatment modality for these patients either due to multiple bone metastases at the time of diagnosis or due to old age in combination with other morbidities. Serum cholesterol levels and statin use were reviewed. We analyzed the factors associated with the development of CRPC after ADT treatment. The mean follow-up period was 34.8 months.Results: The mean age of the patients was 71.3 years old and their mean prostate-specific antigen level was 141.8±212.6 ng/mL. Their mean cholesterol level was 175.9±37.7 mg/dL, and 14 patients (9.1%) were statin users. CRPC developed in 44 patients (28.6%), and the mean duration from ADT treatment to CRPC was 24.1 months. In a multivariate analysis, hypercholesterolemia was associated with the development of CRPC (hazard ratio [HR]=1.017, p＜0.001), depending on clinical T stage (p=0.005) and the presence of bone metastasis (p＜0.001). A subanalysis showed that hypercholesterolemia was associated with the development of CRPC in patients with bone metastasis (HR=1.032, p＜0.001), but not in patients without bone metastasis.Conclusions: Hypercholesterolemia may be associated with the development of CRPC after ADT in patients with bone metastasis. Further studies with longer follow-up periods and larger samples are needed to validate this finding. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002100966 | oai_dc | Urinary Incontinence Could Be Controlled by an Inflatable Penile Prosthesis | Urinary Incontinence Could Be Controlled by an Inflatable Penile Prosthesis | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Hyun Min Choi(Yonsei University); Hyung Ki Choi(Yonsei University); Hye-Yeon Lee(Yonsei University)"
] | Purpose: Due to the increasing numbers of radical prostatectomies (RP) performed for prostate cancer, a substantial and increasing number of patients suffer from postoperative urinary incontinence and erectile dysfunction (ED). The objective of our study was to see whether an inflatable penile prosthesis implantation could control urinary incontinence for patients with the dual problems of ED and incontinence.Materials and Methods: From March 2010 through May 2015, 25 post-RP patients were referred to our clinic with ED or incontinence. The degree of incontinence was classified according to the International Consultation on Incontinence Questionnaire-Short Form. Inflatable penile prostheses were implanted in all 25 patients.Results: For one month after implantation, partial or full inflation was performed progressively to control urine leakage. Of 18 patients, 13 patients were categorized with mild or moderate stress incontinence. All 13 patients obtained control of incontinence with partial inflation (30% to 60%) and all reported satisfactory outcomes. Five out of the 18 patients were categorized with severe total incontinence. Three of the 5 patients could tolerate incontinence with full inflation on and off. Thirteen patients out of the total of 18 (72.2%) had their incontinence controlled by an inflating penile prosthesis.Conclusions: An inflatable penile prosthesis is highly recommended as an initial procedure, especially in patients with the dual problems of ED and incontinence. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002100967 | oai_dc | The Efficacy of Medical Treatment of Peyronie’s Disease: Potassium Para-Aminobenzoate Monotherapy vs. Combination Therapy with Tamoxifen, L-Carnitine, and Phosphodiesterase Type 5 Inhibitor | The Efficacy of Medical Treatment of Peyronie’s Disease: Potassium Para-Aminobenzoate Monotherapy vs. Combination Therapy with Tamoxifen, L-Carnitine, and Phosphodiesterase Type 5 Inhibitor | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박태용(고려대학교); 정형국(고려대학교); 박종진(고려대학교); 채지윤(고려대학교); 김종욱(고려대학교); 오미미(고려대학교); 박홍석(고려대학교); 김제종(고려대학교); 문두건(고려대학교)"
] | Purpose: This study was designed to evaluate the efficacy of medical treatment of Peyronie’s disease.Materials and Methods: A total of 109 patients with Peyronie’s disease who had been treated from January 2011 to December 2014 were retrospectively reviewed in this study. Forty-four patients (Group 1) were treated with 12 mg of potassium para-aminobenzoate daily. Sixty-five patients (Group 2) were treated with combination therapy: tamoxifen (20 mg) and acetyl-L-carnitine (300 mg) twice daily in addition to a phosphodiesterase type 5 inhibitor. Ability to perform sexual intercourse, pain during erection, size of plaque, and penile curvature angle were assessed.Results: In Group 1, 30 of 44 patients (68.2%) discontinued treatment within 12 weeks, while 5 patients (7.7%) in Group 2 discontinued treatment. Pain during erection and plaque size were improved in both groups but showed no statistical difference due to the high dropout rate in Group 1. In both groups, penile curvature was improved, but demonstrated no statistical difference between the treatment groups. However, combination therapy demonstrated a better response rate in patients whose penile curvature angle was less than 30o (44.4% vs. 79.1%, p=0.048). The rate of successful sexual intercourse was significantly higher in Group 2 (42.8% vs. 78.3%, p=0.034). The number of patients who underwent surgical correction despite medical treatment was significantly higher in Group 1 (35.7% vs. 13.3%, p=0.048).Conclusions: Early medical combination therapy in Peyronie’s disease may present better results in patients whose curvature angle is less than 30o. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002100968 | oai_dc | Prospective Randomized Controlled Study on the Efficacy of Multimedia Informed Consent for Patients Scheduled to Undergo Green-Light High-Performance System Photoselective Vaporization of the Prostate | Prospective Randomized Controlled Study on the Efficacy of Multimedia Informed Consent for Patients Scheduled to Undergo Green-Light High-Performance System Photoselective Vaporization of the Prostate | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Dong Yeub Ham(Konkuk University); 최우석(Konkuk University); Sang Hoon Song(Asan Medical Center); Young-Joon Ahn(Seoul National University); 박형근(건국대학교); 김형곤(건국대학교); 손환철(서울대학교)"
] | Purpose: The aim of this study was to evaluate the efficacy of a multimedia informed consent (IC) presentation on the understanding and satisfaction of patients who were scheduled to receive 120-W green-light high-performance system photoselective vaporization of the prostate (HPS-PVP).Materials and Methods: A multimedia IC (M-IC) presentation for HPS-PVP was developed. Forty men with benign prostatic hyperplasia who were scheduled to undergo HPS-PVP were prospectively randomized to a conventional written IC group (W-IC group, n=20) or the M-IC group (n=20). The allocated IC was obtained by one certified urologist, followed by a 15-question test (maximum score, 15) to evaluate objective understanding, and questionnaires on subjective understanding (range, 0∼10) and satisfaction (range, 0∼10) using a visual analogue scale.Results: Demographic characteristics, including age and the highest level of education, did not significantly differ between the two groups. No significant differences were found in scores reflecting the objective understanding of HPS-PVP (9.9±2.3 vs. 10.6±2.8, p=0.332) or in subjective understanding scores (7.5±2.1 vs. 8.6±1.7, p=0.122); however, the M-IC group showed higher satisfaction scores than the W-IC group (7.4±1.7 vs. 8.4±1.5, p=0.033). After adjusting for age and educational level, the M-IC group still had significantly higher satisfaction scores.Conclusions: M-IC did not enhance the objective knowledge of patients regarding this surgical procedure. However, it improved the satisfaction of patients with the IC process itself. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002100969 | oai_dc | Controlling Legal Risk for Effective Hospital Management | Controlling Legal Risk for Effective Hospital Management | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박현준(부산대학교); 조덕영(부산대학교); 박용석(부산대학교); 김선욱(Kim & Hyun Law Firm); 박재홍(Kim & Hyun Law Firm); 박남철(부산대학교)"
] | Purpose: To analyze the types of medical malpractice, medical errors, and medical disputes in a university hospital for the proposal of countermeasures that maximize the efficiency of hospital management, medical departments, and healthcare providers.Materials and Methods: This study retrospectively reviewed and analyzed 55 closed civil lawsuits among 64 medical lawsuit cases carried out in Pusan National University Hospital from January 2000 to April 2013 using medical records, petitions, briefs, and data from the Medical Dispute Mediation Committee.Results: Of 55 civil lawsuits, men were the main plaintiffs in 31 cases (56.4%). The average period from medical malpractice to malpractice proceeding was 16.5 months (range, 1 month to 6.4 years), and the average period from malpractice proceeding to the disposition of a lawsuit was 21.7 months (range, 1 month to 4 years and 11 months).Conclusions: Hospitals can effectively manage their legal risks by implementing a systematic medical system, eliminating risk factors in administrative service, educating all hospital employees on preventative strategies, and improving customer service. Furthermore, efforts should be made to establish standard coping strategies to manage medical disputes and malpractice lawsuits, operate alternative dispute resolution methods including the Medical Dispute Mediation Committee, create a compliance support center, deploy a specialized workforce including improved legal services for employees, and specialize the management-level tasks of the hospital. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001983138 | oai_dc | Electrocautery Resection, Shaving with a Scalpel, and Podophyllin: a Combination Therapy for Giant Condyloma Acuminatum | Electrocautery Resection, Shaving with a Scalpel, and Podophyllin: a Combination Therapy for Giant Condyloma Acuminatum | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Hamed Akhavizadegan(Baharloo Hospital)"
] | Giant condyloma acuminatum (also known as Buschke-Löwenstein tumor) is a rare disease, for which the treatment of choice is still controversial. In the case described in this report, we used a combination of electrocautery and a surgical scalpel to resect a huge genital wart, followed by long-term local treatment with podophyllin. This procedure was relatively fast, easy to perform, involved minimal bleeding, and did not result in any complications. Moreover, combination therapy enabled us to avoid deep resection of the lesion and consequently, sexual function was preserved completely. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001983139 | oai_dc | Modern Oriental Phytotherapy in Sexul Medicine | Modern Oriental Phytotherapy in Sexul Medicine | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김새웅(가톨릭대학교)"
] | 비뇨기과학 | null | kci_detailed_000251.xml | ||||
ART001983132 | oai_dc | Sperm DNA Fragmentation and Standard Semen Parameters in Algerian Infertile Male Partners | Sperm DNA Fragmentation and Standard Semen Parameters in Algerian Infertile Male Partners | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Ghania Belaaloui(Hadj Lakhdar University); Sarah Boushaba(Faculty of Sciences)"
] | Purpose: To date, standard semen parameters have been the only parameters investigated in sperm samples of infertile men in Algeria. We investigated, for the first time, semen parameters according to sperm DNA fragmentation (SDF) in these subjects. Materials and Methods: SDF was determined by a validated sperm chromatin dispersion test in 26 infertile men. Patients were split into two groups according to the SDF level estimated by the DNA fragmentation index (DFI): the low fragmentation group (LFG; LFG with DFI ≤18%) and high fragmentation group (HFG; HFG with DFI ＞18%). The standard semen parameters were measured in both groups.Results: We found that semen concentration and motility were negatively correlated with DFI (r=−0.65, r=−0.45, respectively; p＜0.05), while morphology and semen volume were not correlated with it (r=0.24, r=−0.18, respectively; p＞0.05). Comparison of the sperm concentration revealed that it was significantly higher in LFG than in HFG (37.57%±13.16% vs. 7.32%±3.59%, respectively; p＜0.05), whereas no significant difference was observed regarding sperm motility and morphology.Conclusions: Our findings suggest that SDF correlates well with both sperm motility and concentration but not with morphology. Thus, we conclude that SDF evaluation provides additional information regarding sperm quality, and should be used as a complementary test for assessing semen characteristics in infertile males. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001983133 | oai_dc | Semen Analysis in Cancer Patients Referred for Sperm Cryopreservation before Chemotherapy over a 15-Year Period in Korea | Semen Analysis in Cancer Patients Referred for Sperm Cryopreservation before Chemotherapy over a 15-Year Period in Korea | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"박현준(부산대학교); 구자윤(부산대학교병원); 박남철(부산대학교); Tae Gyeong Jeon(Pusan National University Hospital)"
] | Purpose: This study evaluated the demographics and semen parameters of males with cancer who banked their sperm prior to chemotherapy.Materials and Methods: This is a retrospective study of 66 cases referred for sperm banking prior to initiation of chemotherapy over a 15-year period (1999∼2014). Patients who had previously received cancer treatment including chemotherapy or radiotherapy were not included in this study.Results: We studied a total of 66 cancer patients referred for cryopreservation of sperm prior to chemotherapy. The mean age of the patients at the time of banking was 32.0±7.9 years (range, 19∼58 years). The types of cancer were testicular cancer (31 cases, 47.0%), non-Hodgkin’s disease (10 cases, 15.1%), Hodgkin’s disease (5 cases, 7.6%), leukemia (8 cases, 12.1%), gastrointestinal malignancy (5 cases, 7.6%), and musculoskeletal malignancy (5 cases, 7.6%). There were significant differences in sperm concentration and viability among the various types of cancer, but no significant difference in semen volume or sperm motility and morphology.Conclusions: In this study we found that sperm quality could decrease even before chemotherapy. Because chemotherapy can also negatively affect spermatogenesis, sperm cryopreservation prior to treatment should be strongly recommended for cancer patients of reproductive age. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001983134 | oai_dc | The Effect of Two Weeks of Treatment with Dutasteride on Bleeding after Transurethral Resection of the Prostate | The Effect of Two Weeks of Treatment with Dutasteride on Bleeding after Transurethral Resection of the Prostate | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"문홍상(한양대학교); Kyu Shik Kim(Hanyang University College of Medicine); 정원식(한양대학교); 박성열(한양대학교); 김용태(한양대학교)"
] | Purpose: Dutasteride affects the prostate by reducing intraprostatic dihydrotestosterone and prostate tissue vascularity. We evaluated the effect of pretreatment with dutasteride for two weeks on perioperative and postoperative bleeding during transurethral resection of the prostate (TURP).Materials and Methods: Eighty-three patients who had benign prostatic hyperplasia together with the criteria for eligibility for TURP were included. The dutasteride group consisted of 40 patients who were treated with dutasteride (0.5 mg/d) for two weeks before surgery, and the control group consisted of 43 patients who did not receive dutasteride. Blood loss was evaluated in terms of reduction in serum hemoglobin (Hb) and hematocrit (Hct) levels, which were measured before, immediately after, and 24 hours after surgery. We also measured the durations of indwelling urethral catheter use, continuous saline bladder irrigation, and hospitalization.Results: Lower mean blood loss was observed in the dutasteride group than the control group immediately after and 24 hours after surgery (ΔHb=0.65±1.27 g/dL vs. 1.16±0.73 g/dL, 1.30±1.00 g/dL vs. 1.86±1.05 g/dL respectively, p=0.019, p=0.011; ΔHct=1.89%±3.83% vs. 3.47%±2.09%, 3.69%±2.95% vs. 5.39%±3.23% respectively, p=0.016, p=0.011). In addition, there were fewer days of indwelling urethral catheter use (2.95 ±1.02 d vs. 3.92 ±1.14 d, p=0.000), continuous saline bladder irrigation (1.81 ±1.08 d vs. 2.36 ±1.06 d, p=0.016), and hospitalization after TURP (3.95 ±1.09 d vs. 4.76 ±1.19 d, p=0.001) in the dutasteride group.Conclusions: Preoperative treatment with dutasteride for two weeks before TURP reduces surgical bleeding and length of hospitalization after TURP. This pretreatment can be used to decrease surgical bleeding associated with TURP. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001983135 | oai_dc | Protective Effect of Administered Rolipram against Radiation-Induced Testicular Injury in Mice | Protective Effect of Administered Rolipram against Radiation-Induced Testicular Injury in Mice | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김중선(전남대학교); Wan Lee(Medstar Washington Hospital Center); 손영훈(한국생명공학연구원); Hyosun Jang(Graduate School of Bio-Applications); Min Ji Bae(Dongnam Institute); Jungki Kim(Dongnam Institute); Dongil Kang(Inje University College of Medicine)"
] | Purpose: Pelvic irradiation for the treatment of cancer can affect normal cells, such as the rapidly proliferating spermatogenic cells of the testis, leading to infertility, a common post-irradiation problem. The present study investigated the radioprotective effect of rolipram, a specific phosphodiesterase type-IV inhibitor known to increase the expression and phosphorylation of the cyclic adenosine monophosphate response element-binding protein (CREB), a key factor for spermatogenesis, with the testicular system against pelvic irradiation.Materials and Methods: Male C57BL/6 mice were treated with pelvic irradiation (2 Gy) and rolipram, alone or in combination, and were sacrificed at 12 hours and 35 days after irradiation.Results: Rolipram protected germ cells from radiation-induced apoptosis at 12 hours after irradiation and significantly increased testis weight compared with irradiation controls at 35 days. Rolipram also ameliorated radiation-induced testicular morphological changes, such as changes in seminiferous tubular diameter and epithelial height. Additionally, seminiferous tubule repopulation and stem cell survival indices were higher in the rolipram-treated group than in the radiation group. Moreover, rolipram treatment counteracted the radiation-mediated decrease in the sperm count and mobility in the epididymis.Conclusions: These protective effects of rolipram treatment prior to irradiation may be mediated by the increase in pCREB levels at 12 hours post-irradiation and the attenuated decrease in pCREB levels in the testis at 35 days post-irradiation in the rolipram-treated group. These findings suggest that activation of CREB signaling by rolipram treatment ameliorates the detrimental effects of acute irradiation on testicular dysfunction and the related male reproductive functions in mice. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001983136 | oai_dc | Learning Curve of Robot-Assisted Laparoscopic Radical Prostatectomy for a Single Experienced Surgeon: Comparison with Simultaneous Laparoscopic Radical Prostatectomy | Learning Curve of Robot-Assisted Laparoscopic Radical Prostatectomy for a Single Experienced Surgeon: Comparison with Simultaneous Laparoscopic Radical Prostatectomy | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"하홍구(부산대학교); 구자윤(부산대학교)"
] | Purpose: Despite the large number of analytical reports regarding the learning curve in the transition from open to robot-assisted radical prostatectomy (RARP), few comparative results with laparoscopic radical prostatectomy (LRP) have been reported. Thus, we evaluated operative and postoperative outcomes in RARP versus 100 simultaneously performed LRPs.Materials and Methods: A single surgeon had performed more than 1,000 laparoscopic operations, including 415 cases of radical nephrectomy, 85 radical cystectomies, 369 radical prostatectomies, and treatment of 212 other urological tumors, since 2009. We evaluated operative (operation time, intraoperative transfusion, complications, hospital stay, margin status, pathological stage, Gleason score) and postoperative (continence and erectile function) parameters in initial cases of RARP without tutoring compared with 100 recently performed LRPs.Results: Mean operation time and length of hospital stay for RARP and LRP were 145.5±43.6 minutes and 118.1±39.1 minutes, and 6.4±0.9 days and 6.6±1.1 days, respectively (p=0.003 and p=0.721). After 17 cases, the mean operation time for RARP was similar to LRP (less than 2 hours). Positive surgical margins in localized cancer were seen in 11.1% and 8.9% of cases in RARP and LRP, respectively (p=0.733). At postoperative 3 months, sexual intercourse was reported in 14.0% and 12.0%, and pad-free continence in 96.0% and 81.0% in patients with RARP and LRP, respectively (p=0.796 and p=0.012).Conclusions: Previous large-volume experience of LRPs may shorten the learning curve for RARP in terms of oncological outcome. Additionally, previous experience with laparoscopy may improve the functional outcomes of RARP. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART001983137 | oai_dc | Spontaneous Corpus Cavernosum Abscess in a Healthy Man Using Long-Term Androgenic Anabolic Steroids | Spontaneous Corpus Cavernosum Abscess in a Healthy Man Using Long-Term Androgenic Anabolic Steroids | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Emre Tüzel(Baskent University Zübeyde Hanim Practice and Research Center)"
] | Abscess formation of the corpus cavernosum is very rare. Here, we report a case of long-term anabolic androgenic steroid (AAS) abuse that is suspected to have facilitated the development of a corpus cavernosum abscess in a healthy bodybuilder. Cultures obtained from the abscess contained Staphylococcus epidermidis, a microorganism that almost exclusively affects immunocompromised patients. Therefore, prompt drainage of pus from cavernosal bodies should be the primary aim of the treatment. This case illustrates the potential danger of AAS suppressing the immune system and causing a serious infection. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002133696 | oai_dc | Obesity in Korean Men: Results from the Fourth through Sixth Korean National Health and Nutrition Examination Surveys (2007∼2014) | Obesity in Korean Men: Results from the Fourth through Sixth Korean National Health and Nutrition Examination Surveys (2007∼2014) | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Yeon Won Park(National Police Hospital); Kwi Bok Choi(National Police Hospital); Soon Ki Kim(National Police Hospital); 이동기(경희대학교); Jun Ho Lee(National Police Hospital)"
] | Purpose: Obesity is related to many diseases, including urological conditions. We investigated the prevalence, risk factors, and treatment of male obesity.Materials and Methods: This study included 17,485 men older than 20 years of age who participated in the fourth, fifth, and sixth administrations of the Korean National Health and Nutrition Examination Survey. Two main cutoff points for obesity were defined: a body mass index (BMI) ≥25 kg/m2 and a BMI≥30 kg/m2. Additionally, we defined obesity requiring pharma-cotherapy as the presence of a BMI≥30 kg/m2 or a BMI≥27 kg/m2 co-occurring with at least one associated comorbid medical condition, such as hypertension, dyslipidemia, or diabetes.Results: The prevalence rates of a BMI≥25 kg/m2, a BMI≥30 kg/m2, and obesity requiring pharmacotherapy were 35.7%, 3.4%, and 10.5%, respectively. The prevalence of obesity increased over time for all definitions of obesity. The prevalence of obesity requiring pharmacotherapy was highest in Jeju (12.5%) and lowest in Gangwon-do (7.7%). Having a higher income, being a non-manual worker, and having completed a high level of education were significantly related to obesity requiring pharma-cotherapy. More than 70% of patients with obesity requiring pharmacotherapy reported taking diet pills, eating functional foods, or consuming a one-food diet for weight reduction, but only 13.9% reported exercising for this purpose.Conclusions: Male obesity is a common condition, the prevalence of which is expected to continue to increase over time. A better strategy is required to manage male obesity in Korea. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002133697 | oai_dc | Development of an Improved Animal Model of Overactive Bladder: Transperineal Ligation versus Transperitoneal Ligation in Male Rats | Development of an Improved Animal Model of Overactive Bladder: Transperineal Ligation versus Transperitoneal Ligation in Male Rats | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"김우현(가톨릭대학교); 배웅진(가톨릭대학교); 박중우(가톨릭대학교); 최진봉(가톨릭대학교); 김수진(가톨릭대학교); 조혁진(가톨릭대학교); 하유신(가톨릭대학교); 홍성후(가톨릭대학교); 이지열(가톨릭대학교); 황성연(한국전통의학연구소); 김세웅(가톨릭대학교)"
] | Purpose: We compared a transperineal ligation model and a transperitoneal ligation model in male rats to determine which animal model of overactive bladder (OAB) was more useful based on cystometrography, estimations of oxidative stress, and measurements of pro-inflammatory cytokine levels.Materials and Methods: Male rats were randomly divided into three groups (n=15 in each): the control group, the transperineal ligation group, and the transperitoneal ligation group. Four weeks after the ligation procedure, cystometrography was performed and oxidative stress, pro-inflammatory cytokine levels, and histologic changes were evaluated. Oxidative stress was assessed by measuring 8-hydroxy-20-deoxyguanosine and superoxide dismutase, and pro-inflammatory cytokine activity was investigated by measuring levels of interleukin (IL)-6, IL-8, and tumor necrosis factor-α.Results: The transperineal model led to results similar to those observed for the transperitoneal model, namely (1) increased voiding frequency and reductions in the non-voiding contraction interval and the maximal vesical pressure, (2) increased levels of oxidative stress markers, (3) increased pro-inflammatory cytokine levels, and (4) fibrotic changes in the bladder tissue.Conclusions: We suggest that the transperineal procedure can be used as an alternative OAB model in male rats. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002133698 | oai_dc | Pararectal Migration of a Malleable Rod: An Unusual Late Complication | Pararectal Migration of a Malleable Rod: An Unusual Late Complication | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Ibrahim Kucukturkmen(Izmir Bozyaka Training and Research Hospital); Yusuf Kadir Topcu(Izmir Bozyaka Training and Research Hospital); Tansu Degirmenci(Izmir Bozyaka Training and Research Hospital); Ozgu Aydogdu(Izmir Bozyaka Training and Research Hospital); Ibrahim Halil Bozkurt(Izmir Bozyaka Training and Research ... | A 75-year-old male had failed to respond conservative therapy for erectile dysfunction and had undergone insertion of a malleable penile prosthesis in 1995. Twenty years after the initial implant he presented with right-sided prosthesis localized in the buttock. There was no infection. The prosthesis was extracted through an incision in the right hip. As in the recent case, mechanical failures in malleable penile prosthesis models, can occur. Penile implant migration back to the buttock without a curve deformity is an extremely rare complication. Clinicians should be alert about possible late complications of penile prosthesis. | 비뇨기과학 | null | kci_detailed_000251.xml | |||
ART002133699 | oai_dc | Gigantic Suprapubic Lymphedema: A Case Study | Gigantic Suprapubic Lymphedema: A Case Study | {
"journal_name": "대한남성과학회",
"publisher": null,
"pub_year": null,
"pub_month": null,
"volume": null,
"issue": null
} | [
"Roozbeh Tanhaeivash(Department of Urology,Friedrich Schiller University); Tobias Franiel(Institute of Radiology, Friedrich Schiller University); Marc-Oliver Grimm(Department of Urology,Friedrich Schiller University); Marcus Horstmann(Department of Urology,Friedrich Schiller University)"
] | We present the first case study of idiopathic gigantic suprapubic lymphedema and buried penis treated with puboscrotal reconstruction in a patient with initial extreme obesity after an extensive weight reduction (120 kg). Massive localized lymphedema of the suprapubic region should be differentiated from the scrotal type. Severe lymphedema could not resolve on its own and weight reduction does not seem to be helpful in such cases. | 비뇨기과학 | null | kci_detailed_000251.xml |
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