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1,436 | Difference in beta 2-microglobulin removal between cellulosic and synthetic polymer membrane dialyzers.
Several kinds of dialyzers, with highly permeable membranes (HPM), have been designed to specifically remove beta 2-microglobulin (BMG).
To clarify their solute transport characteristics, nine types of HPM dialyzer... | 11 |
1,737 | Calciotropic hormones in human and experimental hypertension.
Although altered cellular calcium handling plays a critical role in the pathophysiology of hypertension, little attention has been focused on the impact of calcium regulating hormones on this process.
Recent research provides evidence that parathyroid horm... | 13 |
669 | Effect of a pulsing electromagnetic field on metabolically derived osteoporosis in rats: a pilot study.
The literature suggests that a pulsating electromagnetic field (PEMF) is effective against bone loss in disuse osteoporosis.
This study was conducted to evaluate the effects of PEMF on metabolically derived osteopo... | 4 |
1,190 | Selective spatial attention in patients with visual extinction.
The present study was designed to verify the attentional performance of patients with parietal lesions in the experimental condition in which they had to pay attention to 3 spatial positions located on the left, on the right and directly above the fixatio... | 9 |
1,837 | Effects of nitroprusside on transmitral flow velocity patterns in extreme heart failure: a combined hemodynamic and Doppler echocardiographic study of varying loading conditions.
To explore the mechanisms of change of left ventricular diastolic filling associated with preload and afterload reduction, the influence of ... | 13 |
2,858 | Alcohol consumption and problem drinking in Vietnam era veterans and nonveterans.
The relationship between Vietnam era veteran status and 13 indicators of alcohol consumption and problem drinking is examined using data from the 1977, 1983 and 1985 National Health Interview Surveys conducted by the National Center for ... | 20 |
565 | Breast cancer: the military's experience at Wilford Hall USAF Medical Center.
We reviewed the experience with breast cancer at Wilford Hall USAF Medical Center for the years 1978 through 1988.
A total of 868 cases were identified in the Wilford Hall Tumor Registry; overall 5-year and 10-year survivals were 63% and 39... | 3 |
2,371 | Family of glucose-transporter genes. Implications for glucose homeostasis and diabetes.
Glucose transport by facilitated diffusion is mediated by a family of tissue-specific membrane glycoproteins.
At least four members of this gene family have been identified by cDNA cloning.
The HepG2-type transporter is the most ... | 17 |
660 | The effect of stem stiffness on femoral bone resorption after canine porous-coated total hip arthroplasty.
Bilateral noncemented total hip arthroplasty (THA) was produced in dogs to determine the effect of stem stiffness on stress-related bone resorption.
Two porous-coated femoral implants of substantially different ... | 4 |
1,301 | Comparison of albumin excretion rate obtained with different times of collection.
This study was undertaken to assess the usefulness of different techniques for determination of albumin excretion rate (AER).
Ninety patients with type I (insulin-dependent) diabetes mellitus and 45 with type II (non-insulin-dependent) ... | 11 |
831 | Breast-feeding and diarrheal morbidity.
This study used a unique longitudinal survey of more than 3000 mother-infant pairs observed from pregnancy through infancy.
The sample is representative of infants from the Cebu region of the Philippines.
The sequencing of breast-feeding and diarrheal morbidity events was care... | 5 |
2,480 | Mild hypoglycemia and impairment of brain stem and cortical evoked potentials in healthy subjects.
To evaluate the impact of mild hypoglycemia on CNS function in healthy adults, we measured brain stem auditory evoked potentials and P300 potentials (elicited by cognitive processing of auditory stimuli) during hypoglyce... | 17 |
386 | Procarbazine chemotherapy in the treatment of recurrent malignant astrocytomas after radiation and nitrosourea failure.
The Brain Tumor Study Group has shown procarbazine (PCB) to be as effective an adjuvant treatment as 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
We treated 35 patients with recurrent malignant astr... | 3 |
3,172 | Mutations in src homology regions 2 and 3 of activated chicken c-src that result in preferential transformation of mouse or chicken cells.
src homology regions 2 and 3 (SH2 and SH3) of proteins encoded by src and closely related genes are conserved domains believed to modulate the protein-tyrosine kinase activity of t... | 22 |
613 | The inwardly pointing knee. An unrecognized problem of external rotational malalignment.
Twelve patients with inwardly pointing knees had chronic knee pain and disability suggestive of patellofemoral subluxation.
None had responded well to conservative measures or surgical correction at the level of the soft tissues.... | 4 |
776 | Binding to human jejunum of serum IgA antibody from children with coeliac disease.
Jejunal histology and the presence of serum IgA antibodies (JAB) binding to human jejunum in vitro were studied in 139 children with severe malabsorptive symptoms.
Among 33 children with confirmed coeliac disease (ESPGAN criteria), 13 ... | 5 |
3,326 | The distribution of enkephalins in human carotid bodies showing cellular proliferation and chronic glomitis.
Human carotid bodies obtained at necropsy that showed prominence of either the sustentacular cell or the dark variant of chief cell or chronic carotid glomitis were studied by an immunogold labeling technique.
... | 22 |
821 | Nonoperative management of bile duct stones.
The treatment of choice for most retained bile duct stones is by nonoperative means.
If a T-tube is in place, percutaneous techniques via the T-tract are indicated.
Percutaneous access via puncture of a Roux-en-Y loop is also practical.
In the absence of a T-tube, retrog... | 5 |
339 | Clinical evaluation of a side entry access port: a novel dual-lumen venous access device.
The initial clinical experience with a low-profile side entry access (SEA) dual-lumen implantable venous access port for cancer chemotherapy administration is summarized in this report.
The catheter material is polyurethane.
Th... | 3 |
1,831 | Endothelin family in human plasma and cerebrospinal fluid.
To clarify whether endothelin may be present in human cerebrospinal fluid (CSF) and, if it exists, to compare its molecular forms with those of endothelin in human plasma, we analyzed pooled human CSF and plasma by high performance liquid chromatography with s... | 13 |
1,859 | Quantification of the reversibility of stress-induced thallium-201 myocardial perfusion defects: a multicenter trial using bull's-eye polar maps and standard normal limits
A multicenter trial was performed on 140 patients from four centers to determine the accuracy of quantitative analysis of stress/delayed thallium-... | 13 |
625 | Polymyositis: a case history approach to the differential diagnosis and treatment.
A wide range of conditions can mimic polymyositis.
Thus, diagnosing this condition can be a challenge.
Although no single criterion is diagnostic of polymyositis, the following criteria have been proposed and widely used: (1) symmetri... | 4 |
2,544 | The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms.
The effect of the selective serotonin reuptake inhibitor paroxetine on diabetic neuropathy symptoms was examined in comparison to imipramine and placebo in a randomised, double-blind, cross-over study.
... | 18 |
2,594 | Full-length recombinant CD4 and recombinant gp120 inhibit fusion between HIV infected macrophages and uninfected CD4-expressing T-lymphoblastoid cells.
Human immunodeficiency virus-(HIV) infected monocyte-macrophages may contribute to the pathogenesis of HIV-associated immune deficiency and dysfunction by acting as a ... | 19 |
2,211 | Effect of maternal smoking and age on congenital anomalies.
The incidence of congenital anomalies was examined by the level of maternal and paternal smoking during pregnancy for 17,152 infants.
A multiple regression analysis was used to control for the possible confounding effects of maternal age, formal education, e... | 15 |
1,727 | Randomized trials in the study of antihypertensive drugs.
Heterogeneity in response to antihypertensive drugs can be addressed by randomized trials in individual subjects.
In such a trial a patient receives pairs of treatment periods (one period of each pair active drug, one matched placebo, in random order); patient... | 13 |
2,087 | An analysis of outcome following percutaneous transluminal coronary artery angioplasty. An autopsy series.
We analyzed autopsy findings on 26 patients who died following percutaneous transluminal coronary angioplasty (PTCA).
Twenty-one patients died within 3 weeks of undergoing PTCA; demonstrable cardiac complication... | 13 |
2,745 | Corticocancellous grafting and an AO/ASIF lag screw for nonunion of the scaphoid. A retrospective analysis.
We report our experience in 42 patients, using corticocancellous bone grafts and lag screw fixation for un-united scaphoid fractures.
Using a grading system, we analysed the suitability of the method for three ... | 20 |
2,307 | Immunosuppressive effects of clonidine on the induction of contact sensitization in the balb/c mouse.
The clonidine transdermal therapeutic system (clonidine-TTS) has been associated with a significant incidence of allergic contact sensitization.
This incidence was not predicted by premarket skin sensitization testin... | 16 |
1,827 | Successful surgical treatment of subaortic stenosis caused by an accessory mitral valve.
A 22-month-old boy with subaortic stenosis was found to have relatively mature mitral valve tissue beneath the aortic valve, associated with a hypertrophic and prominent interventricular septum.
This tissue caused obstruction of ... | 13 |
2,716 | Effect of digitalis on clinical symptoms and conduction variables in patients with multiple sclerosis.
Digitalis has been shown to reverse conduction block in demyelinated nerve fibers in experimental animals.
In the search for a symptomatic treatment of multiple sclerosis, digoxin (0.02 mg per kilogram of body weigh... | 19 |
3,324 | An evaluation of the Level 1 blood warmer series
The Level 1 blood warmer series comprises three infusion sets and two blood warmers of different power outputs.
All systems were found to be extremely efficient, with the larger 500 series capable of warming the equivalent of 80 units of blood an hour almost to body t... | 22 |
3,063 | Temporary cardiac pacing using a new, steerable, balloon-tipped pacing catheter.
A new balloon-tipped, flow-directed, steerable pacing catheter for unipolar temporary ventricular pacing is presented.
It was successfully and uneventfully tested in 25 patients with acute myocardial infarction in the coronary care unit.... | 22 |
55 | Limited efficacy of a Haemophilus influenzae type b conjugate vaccine in Alaska Native infants. The Alaska H. influenzae Vaccine Study Group
BACKGROUND.
The prevention of invasive Haemophilus influenzae type b disease requires a vaccine that is effective when administered during the first six months of life.
The in... | 0 |
699 | Inter- and intraindividual variation in pressure-volume relations of the rectum in normal subjects and patients with the irritable bowel syndrome.
The relation between intrarectal volume and pressure during increasing rectal distension by a latex balloon were studied on repeated occasions in 10 healthy adult volunteer... | 5 |
1,611 | Vena caval flow: assessment with cine MR velocity mapping.
The authors used cine magnetic resonance (MR) velocity mapping to study flow in the superior vena cava (SVC) and inferior vena cava (IVC) of 13 healthy control subjects and 13 patients with right-sided cardiac disease.
In the control subjects, peaks of flow i... | 13 |
2,079 | Left ventricular filling impairment in asymptomatic chronic alcoholics.
Systolic left ventricular dysfunction is relatively common in even asymptomatic alcoholics, but whether diastolic function is also altered is much less well-studied.
We used M-mode and Doppler echocardiography to study left ventricular size, mass... | 13 |
822 | Surgical management of bile duct stones.
The biliary surgeon in the 1990s must be familiar with all of the available techniques for the treatment of bile duct stones.
Experience and judgment are important in the successful management of the individual patient with intrahepatic or extrahepatic stones.
Knowledge of th... | 5 |
1,720 | Financial impact of a rapid CK-MB-specific immunoassay on the diagnosis of myocardial infarction.
The purpose of this study was twofold.
First, we evaluated the financial impact of a rapid, monoclonal antibody-based CK-MB mass assay (Stratus, Dade Division, Baxter Laboratories, Miami, Fla) for the direct measurement ... | 13 |
177 | Immunophenotypes in "classical" B-cell chronic lymphocytic leukemia. Correlation with normal cellular counterpart and clinical findings.
This study evaluates the expression of a series of membrane antigens, normally expressed by B-lymphocytes of the lymphocytic mantle and marginal zone, in 90 selected cases of "classi... | 3 |
803 | A pitfall in azygos vein cannulation in cirrhotic patients: mistaken cannulation of the mammary vein.
Azygos venous flow can be measured by a thermodilution catheter in patients with cirrhosis.
This is a useful technique since azygos flow is thought to reflect the superior portosystemic collateral flow in these patie... | 5 |
700 | Pancreatic function in Crohn's disease.
We investigated exocrine pancreatic function in a population of patients with Crohn's disease in order to correlate the pancreatic function with clinical and laboratory variables.
A total of 143 patients affected by Crohn's disease and 115 control subjects were studied.
All ha... | 5 |
2,381 | Practical nutritional advice for the elderly, Part I: Evaluation, supplements, RDAs. A geriatrics panel discussion.
By the time someone reaches old age, he or she thinks they know everything they want, or need, to know about nutrition.
Yet malnutrition and its many effects are a rising danger.
In this first of two i... | 17 |
904 | Selective IgG subclass deficiencies and antibody responses to pneumococcal capsular polysaccharide antigen in adult community-acquired pneumonia.
We measured the serum concentrations of IgG subclasses in healthy subjects (n = 26) and in patients with community-acquired pneumonia (CAP) on admission (n = 38), at recover... | 7 |
3,320 | Low-dose aspirin versus anticoagulants for prevention of coronary graft occlusion.
The prevention of graft occlusion by aspirin (100 mg/day) or heparin followed by phenprocoumon was investigated in a randomized trial in 235 patients after aortocoronary bypass operation.
Aspirin treatment started 24 hours before, and ... | 22 |
1,196 | Lack of change in neurochemical markers during the postepileptic phase of intrahippocampal tetanus toxin syndrome in rats.
The chronic epileptic syndrome induced by injecting tetanus toxin into rat hippocampus causes functional changes that essentially are permanent, outlasting the period of active seizures by at leas... | 9 |
260 | Bactericidal effect of doxycycline associated with lysosomotropic agents on Coxiella burnetii in P388D1 cells.
There is no consistently reliable treatment for endocarditis resulting from chronic Coxiella burnetii infection, the causative agent of Q fever.
Although certain antibiotics are recommended on the basis of t... | 3 |
2,591 | D-penicillamine-induced lupus erythematosus.
We describe a patient who presented with polyarthritis, pleurisy, rash, and a positive antinuclear antibody result after 5 years of D-penicillamine therapy.
D-penicillamine-induced antinuclear antibodies were mainly high-titer IgG directed against the (H2A-H2B)-DNA complex... | 19 |
556 | Gamma-detecting probe and autoradiographic studies of radiolabeled antibody B72.3 in CX-1 colon xenografts.
Nude mice bearing CX-1 colon tumors were injected with 50 microCi 125I-labeled monoclonal antibody (MAb) B72.3.
Radioactivity in tumors was studied with the gamma detecting probe (GDP) on days 1, 3, 7, and 10 a... | 3 |
2,322 | A substitution at a non-glycine position in the triple-helical domain of pro alpha 2(I) collagen chains present in an individual with a variant of the Marfan syndrome.
A substitution for a highly conserved non-glycine residue in the triple-helical domain of the pro alpha 2(I) collagen molecule was found in an individu... | 16 |
3,057 | Hormone implants and tachyphylaxis.
The serum oestradiol levels of 1388 women treated with hormone implants at a menopause clinic were reviewed in 1988.
Thirty-eight (3%) were found to be above 1750 pmol/l.
Of these 38 women with supraphysiological oestradiol levels 23 had started therapy for menopausal symptoms and... | 22 |
2,050 | Medical management of chronic heart failure: inotropic, vasodilator, or inodilator drugs?
On the basis of pathophysiologic mechanisms, the medical therapy of today for chronic heart failure is reviewed.
The advantages and disadvantages of the vasodilator drugs and the inotropic drugs are presented.
Finally, the ther... | 13 |
3,235 | Aplasia cutis congenita and arteriovenous fistula. Case report and review.
We describe a child with congenital aplasia cutis congenita of the scalp and an occult giant posterior fossa arteriovenous fistula.
Previous case reports of central nervous system malformations associated with aplasia cutis congenita are revie... | 22 |
1,578 | Two-way factorial study of alcohol and salt restriction in treated hypertensive men.
The aim of this study was to determine whether moderate restriction of dietary salt intake leads to an additional fall in blood pressure in treated hypertensive men who are asked to simultaneously reduce their usual alcohol intake.
S... | 13 |
1,958 | Cardioplegia-induced damage to ischemic immature myocardium is independent of oxygen availability.
The known benefits of hypothermic pharmacological cardioplegia in protecting the ischemic adult heart may not extend to children.
Protection of the ischemic immature rabbit heart with hypothermic Krebs-Henseleit bicarbo... | 13 |
3,117 | Reproducibility of growth hormone testing procedures: a comparison between 24-hour integrated concentration and pharmacological stimulation.
The purpose of this study was to compare the reproducibility of two approaches to the evaluation of GH secretion: the integrated concentration of GH (IC-GH), a physiological test... | 22 |
1,563 | Left main percutaneous transluminal coronary angioplasty with the autoperfusion catheter in an animal model.
Left main coronary angioplasty is associated with high risk because of interruption of blood flow to much of the left ventricle during balloon inflation.
An "autoperfusion" balloon angioplasty catheter that al... | 13 |
2,123 | Alterations in endocardial vascular resistance after reperfusion in a low flow, high demand model of ischemia: effects of dipyridamole and WEB-2086, a platelet-activating factor antagonist.
To determine if alterations in regional coronary vascular resistance could occur in the type of myocardial ischemia present in se... | 13 |
928 | Platelet-activating factor- and leukotriene B4-induced release of lactoferrin from blood neutrophils of atopic and nonatopic individuals.
We found increased accumulation of neutrophils and their components, lactoferrin (Lf) and elastase, as well as platelet-activating factor (PAF) and leukotriene B4 (LTB4) at sites of... | 7 |
2,818 | Hypophosphatemia--incidence, etiology, and prevention in the trauma patient.
Hypophosphatemia is associated with a number of undesirable physiologic consequences and has been reported to occur frequently in trauma patients.
We studied patients in the immediate posttraumatic period to document a) the decrease in serum... | 20 |
813 | NSAID-induced gastrointestinal damage. A critical review of prophylaxis and therapy.
Nonsteroidal anti-inflammatory drugs (NSAIDs) cause acute diffuse injury to the gastroduodenal mucosa, and also cause chronic focal ulcers that may bleed or perforate without warning symptoms.
Acute and chronic lesions are distinct, ... | 5 |
621 | Musculoskeletal impairments and physical disablement among the aged.
This article summarizes the results of a longitudinal investigation of the progression of sight, hearing, and musculoskeletal impairments and their association with change in physical disability, in 10 ADLs among members of the Massachusetts Health C... | 4 |
2,946 | Trend toward nonoperative management of splenic injuries.
Treatment of splenic injuries has evolved over the past decade to reflect more effort to conserve function of the spleen.
Records of 169 patients admitted over a 6-year period were identified as documenting the treatment of splenic injuries.
We collected data... | 20 |
68 | Epidemiology of Lyme disease in Virginia.
Prior to January 1986, only one case of Lyme disease was reported from Virginia.
In 1986-87, however, the Virginia Department of Health observed an increase in reports of suspected Lyme disease by physicians, despite the fact that Ixodes dammini is not highly prevalent in the... | 0 |
2,535 | Training obstetrics-and-gynecology residents to manage breast disease. Incorporation into a breast care clinic.
The American Board of Obstetricians and Gynecologists recently issued a directive that education in breast disease be incorporated into all residency training programs.
At the University of Michigan Medical... | 18 |
490 | Lack of relationship between perioperative blood transfusion and survival time after curative resection for gastric cancer.
To better comprehend the relationship between perioperative blood transfusion and survival time after curative gastrectomy for advanced gastric cancer, the authors reviewed retrospectively data o... | 3 |
1,962 | Current status of antitachycardia devices.
With the limitations of currently available modalities for treating clinically important tachycardias, the role of implanted antitachycardia devices will continue to expand.
The challenge of the future will not only involve continued technological advances but the socioecono... | 13 |
1,318 | Current options in the management of clinical stage C prostatic carcinoma.
The evaluation of clinical stage C prostatic cancer has been enhanced by advances in staging modalities over the past 15 years.
Better staging of the local lesion is possible with transrectal ultrasound-guided multiple biopsies of the prostate... | 11 |
1,978 | Fibrinopeptide A is released into the coronary circulation after coronary spasm.
To examine whether acute myocardial ischemia activates the coagulation system and platelet activation in the coronary circulation, we measured plasma levels of fibrinopeptide A and beta-thromboglobulin in the coronary sinus and the aortic... | 13 |
1,579 | Diurnal cardiovascular patterns in spontaneously hypertensive and Wistar-Kyoto rats.
This study was designed to determine whether diurnal patterns of blood pressure, heart rate, or locomotor activity differed among two substrains of Wistar-Kyoto rats, derived originally from Charles River or Taconic Farms stock, or th... | 13 |
2,613 | Characteristics of patients with food-related complaints.
Forty-five patients with classic food-allergic symptoms and/or subjective food-related complaints not traditionally associated with food allergy underwent evaluation.
On the basis of a comprehensive clinical history, skin testing, and placebo-controlled, doubl... | 19 |
589 | Photopheresis for the treatment of cutaneous T cell lymphoma.
We investigated the use of extracorporeal chemotherapy (photopheresis) in eight patients with cutaneous T cell lymphoma.
Initially described by Edelson et al.
for the treatment of erythrodermic cutaneous T cell lymphoma, we have expanded the treatment to ... | 3 |
1,032 | Localized antigen challenge of the nasal mucosa.
We describe a localized nasal antigen challenge and the measurement of mediators found at the same site.
Eight ragweed-allergic subjects were challenged on 2 days, 1 week apart.
Challenges consisted of six sequential provocations, beginning with two control challenges... | 8 |
2,222 | Persistent right umbilical vein: an ominous prenatal finding?
The persistence of a right umbilical vein is an uncommon finding, with only a dozen cases reported since 1826.
The persistent right umbilical vein may replace the normal left umbilical vein or be supernumerary.
The anomaly is associated with numerous and ... | 15 |
2,377 | Limited duration of remission of insulin dependency in children with recent overt type I diabetes treated with low-dose cyclosporin.
Preliminary data from our group indicated that cyclosporin A induced frequent remissions of insulin dependency in a group of 40 insulin-dependent (type I) diabetic children if given at t... | 17 |
716 | Immunohistochemical detection of abnormal cell proliferation in colonic mucosa of subjects with polyps.
Previous studies have shown the presence of increased proliferation in the large bowel epithelium of those at high risk of developing colon cancer.
An in vitro technique for labelling large bowel mucosa with the th... | 5 |
1,888 | Coarctation of the aorta.
Coarctation of the aorta is a common cardiovascular disorder with an unknown etiology.
In the preductal type, blood flows from a patent ductus into the distal aorta.
When the coarctation is juxtaductal or postductal, blood flows to the lower extremities by way of the subclavian arteries and... | 13 |
618 | Evaluation of an electrogoniometric instrument for measurement of laxity of the knee.
Eight lower extremities from cadavera were tested for anterior-posterior laxity in two positions before and after transection of the anterior cruciate ligament.
At critical points in the tests, electrogoniometric and radiographic me... | 4 |
2,596 | Ability of anti-HIV agents to inhibit HIV replication in monocyte/macrophages or U937 monocytoid cells under conditions of enhancement by GM-CSF or anti-HIV antibody.
Monocyte/macrophages (M/M) are an important target cell for human immunodeficiency virus (HIV) infection in the body.
The study of HIV infection in the... | 19 |
1,291 | Hemihang-back recession: description of the technique and review of the literature.
We describe a modification of the hang-back and loop techniques that we call the hemihang-back recession, in which the muscle is reattached to the sclera posterior to the original insertion with a single, absorbable suture.
We recomme... | 10 |
1,294 | Role of communities in decision-making eye care programs.
The concept of primary health care involves educating people to live their lives in ways beneficial to their health.
Communities as a whole must participate in the decision-making that is involved in such education, be it promotive, preventive, curative, or re... | 10 |
95 | A general model of sexually transmitted disease epidemiology and its implications for control.
Achieving control of STDs may be possible by integrating the activities discussed previously with further research to provide additional empiric data on sex behavior, to develop innovative strategies to access and communicat... | 0 |
1,592 | Transesophageal Doppler color flow mapping assessment of atrial septal defect.
Transesophageal Doppler color flow imaging was performed in 19 adult patients (mean age 35 years) with an atrial septal defect demonstrated by cardiac catheterization or at surgery, or both.
The transesophageal study correctly identified a... | 13 |
2,548 | Reappraisal of thyroxine treatment in primary hypothyroidism.
The optimum daily dose of thyroxine was calculated for 13 children aged 3-16 years with primary hypothyroidism by titrating their doses at monthly intervals.
The condition of the thyroid was assessed by sensitive assay of thyroid stimulating hormone concen... | 18 |
3,350 | Predictors of quitting smoking: the NHANES I followup experience.
There are no published prospective studies on the predictors of spontaneously quitting cigarette smoking in a nationally-representative U.S.
population.
This paper describes such a study, using a cohort taken from the First National Health and Nutriti... | 22 |
2,133 | Transfusion and alloimmunization in sickle cell disease. The Cooperative Study of Sickle Cell Disease.
In 1,814 patients with sickle cell disease who had been transfused, the overall rate of alloimmunization to erythrocyte antigens was 18.6%.
The rate of alloimmunization in this group appears to be an explicit functi... | 14 |
2,096 | A novel mechanical cardiac assist device for reversing left ventricular failure.
Diastolic augmentation of aortic pressure is an efficacious means of improving coronary perfusion in heart failure.
A novel mechanical cardiac assist device (MCAD), that has advantages over a conventional intraaortic balloon pump and lef... | 13 |
2,066 | Pineal hyperactivity in spontaneously hypertensive rats: muscarinic regulation of indole metabolism.
1.
Choline acetyltransferase activity and [3H]quinuclidinyl benzylate-binding sites were detected in the pineal gland of normotensive Wistar-Kyoto rats and of spontaneously hypertensive rats.
2.
In vitro, muscarinic... | 13 |
1,710 | Intravascular ultrasound: a new potential modality for angioplasty guidance.
Current angioplasty devices are limited by significant rates of arterial perforation and dissection, due to inadequate techniques of guidance, and by restenosis, which may be partly attributed to inadequate debulking of lesions.
This paper d... | 13 |
951 | A family study of the variability of pulmonary function in alpha 1-antitrypsin deficiency. Quantitative phenotypes.
A group of 52 alpha 1-antitrypsin-deficient individuals of phenotype Pi Z and 117 of their relatives underwent a protocol including pulmonary function testing, completion of a questionnaire, and blood do... | 7 |
1,236 | pH-adjustment and discomfort caused by the intradermal injection of lignocaine [published erratum appears in Anaesthesia 1991 Mar;46(3):242]
One hundred adult day-case patients who required intravenous access had cannulae inserted using local anaesthesia with 1% lignocaine, 1% lignocaine with adrenaline or the corresp... | 9 |
2,690 | Effect of thromboxane antagonists on ozone-induced airway responses in dogs.
Airway hyperresponsiveness after inhaled ozone in dogs may occur as a result of thromboxane release in the airway.
In this study, two thromboxane receptor antagonists, L-655,240 and L-670,596, were used in doses that inhibit the response to ... | 19 |
139 | Impact of mass treatment of onchocerciasis with ivermectin on the transmission of infection.
Onchocerciasis is a major blinding disease that, until recently, has been essentially untreatable.
Ivermectin is a safe and effective drug for the mass treatment of onchocerciasis and when used on an individual basis, it redu... | 2 |
245 | The prognostic significance of CA 125 half-life in patients with ovarian cancer who have received primary chemotherapy after surgical cytoreduction.
Fifty-four patients with advanced epithelial ovarian cancer were monitored with serial serum CA 125 levels after surgical cytoreduction and during multi-agent chemotherap... | 3 |
2,253 | Activation pathways of synovial T lymphocytes. Expression and function of the UM4D4/CDw60 antigen.
Accumulating evidence implicates a central role for synovial T cells in the pathogenesis of rheumatoid arthritis, but the activation pathways that drive proliferation and effector function of these cells are not known.
... | 16 |
562 | Vaccination against tumor cells expressing breast cancer epithelial tumor antigen.
Ninety-one percent of breast tumors aberrantly express an epithelial tumor antigen (ETA) identified by monoclonal antibody H23.
Vaccinia virus recombinants expressing tumor antigens have considerable promise in the active immunotherapy... | 3 |
1,193 | Continuous removal of middle molecules by hemofiltration in patients with acute liver failure.
In patients with acute liver failure and hepatic coma, an increase in the abnormal "middle molecules" seen on the chromatograms of the sera is suspected of playing an etiologic role in the coma.
A pilot study of continuous ... | 9 |
1,055 | A prospective, double-blind study of metoclopramide hydrochloride for the control of migraine in the emergency department
STUDY OBJECTIVE: To determine the effectiveness of IV metoclopramide as sole therapy for relieving the pain of acute migraine in the emergency department.
DESIGN: Prospective study.
Fifty patien... | 9 |
863 | The prevalence of periodontitis in a military treatment population.
A group of 1,984 males and females (age range 13 to 84) at a military dental clinic were given oral examinations with full-mouth circumferential periodontal probing.
Diagnoses were made both for individual quadrants and for the entire mouth using cle... | 6 |
2,983 | Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart.
To determine the effects of age on the myocardium, the functional and structural characteristics of the heart were studied in rats at 4, 12, 20, and 29 months of age.
Mean arterial pressure, left ventricular pressure and its firs... | 22 |
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