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2,720 | Genomic divergence of an HIV-2 from a German AIDS patient probably infected in Mali.
The complete nucleotide sequence of an HIV-2 isolate derived from a German AIDS patient with predominantly neurological symptoms is reported.
The HIV-2BEN sequence is highly divergent from those of previously described HIV-2 and SIV ... | 19 |
2,155 | Immunoglobulin G subclasses in serum and circulating immune complexes in patients with Kawasaki syndrome.
IgG subclass concentrations in sera of 17 patients with Kawasaki syndrome were determined.
Significantly increased IgG1 (P less than 0.001) and IgG3 (P less than 0.001) were found in the patients compared with 22... | 14 |
2,329 | Induction of ornithine decarboxylase following sellotape stripping in normal and psoriatic skin.
Ornithine decarboxylase (ODC) was measured in the epidermis of healthy volunteers and the uninvolved skin of psoriatic patients at various times after sellotape stripping.
Basal levels were less than 1 pmol/min/mg protein... | 16 |
3,341 | Effect of complement and arachidonic acid pathway inhibition on white blood cell count and deposition on vascular grafts.
To determine the role of complement and arachidonic acid metabolites in the decrease in peripheral white blood cell count (pWBC) observed with graft implantation, Dacron aortic grafts were implante... | 22 |
2,684 | Transfusion-induced graft-versus-host disease in patients with malignant lymphoma. A case report and review of the literature.
A case of transfusion-induced graft-versus-host disease (GVHD) occurring in a 31-year-old female with Hodgkin's disease in complete remission is reported.
Clinical features are similar to 19 ... | 19 |
1,452 | Pathophysiology of prolonged penile erection associated with trazodone use.
Treatment with the antidepressant trazodone has been associated with the occurrence of prolonged penile erection and priapism.
To evaluate the effect of trazodone on erection we monitored the periodic physiological sleep-related erections in ... | 11 |
765 | Frequency of recovery of Blastocystis hominis in clinical practice.
We examined the frequency of isolation of Blastocystis hominis from stools of patients seen in an indigent-care teaching hospital.
Over a 2-year period, 2,744 stool specimens were examined prospectively.
B.
hominis was found in 262 stools (9.5% of ... | 5 |
991 | Intact epithelial barrier function is critical for the resolution of alveolar edema in humans
Within 15 min of endotracheal intubation, the resolution of pulmonary edema was studied over the next 12 h in 34 mechanically ventilated patients by (1) serial measurements of the alveolar-arterial oxygen difference, (2) the... | 7 |
1,073 | Double-blind comparison of topical lignocaine-prilocaine cream (EMLA) and lignocaine infiltration for arterial cannulation in adults.
In a double-blind, double-dummy study, the efficacy of topical 5% EMLA cream was compared with that of lignocaine infiltration in alleviating the pain of arterial cannulation.
Forty un... | 9 |
2,510 | Metabolic control and complications over 3 years in patients with insulin dependent diabetes (IDDM): the Stockholm Diabetes Intervention Study (SDIS).
In a planned 5-year study, 97 patients with insulin dependent diabetes mellitus (IDDM), non-proliferative retinopathy and unsatisfactory blood glucose control were moni... | 17 |
1,268 | Caspar Stromayr: sixteenth century ophthalmologist.
Caspar Stromayr, ophthalmologist and hernia surgeon, is credited with writing the first German ophthalmic work of known authorship.
Written in about 1559 as an appendix to Practica Copiosa, a larger work on hernia surgery, the ophthalmic chapters describe Stromayr's... | 10 |
2,898 | Age effect on prognosis for functional recovery in acute, traumatic central cord syndrome.
The purpose of this study was to determine if age is significant in functional recovery in acute, traumatic central cord syndrome (CCS).
Recovery of ambulation, ADL status, and bowel and bladder function were evaluated.
A retr... | 20 |
2,585 | Effects of deep inhalation during early and late asthmatic reactions to allergen [published erratum appears in Am Rev Respir Dis 1991 Feb;143(2):451]
Eighteen asthmatic patients with a biphasic asthmatic reaction to house dust mite were studied.
The effect of deep inhalation (DI) was quantitated by comparing the maxi... | 19 |
1,523 | Cryopreserved/thawed semen for in vitro fertilization: results from fertile donors and infertile patients.
We evaluated the in vitro fertilization (IVF) outcome in 54 cycles using cryopreserved/thawed semen from fertile donors.
Controls were other IVF patients matched by time frame, female age, stimulation protocol, ... | 12 |
769 | Morphological study of cholesterol hepatolithiasis. Report of three cases.
Three cases of pure cholesterol intrahepatic stones are compared morphologically to those of calcium bilirubinate stones.
Cholesterol stones were found in the intrahepatic bile duct of the left lateral lobe in two cases and in both the left la... | 5 |
2,267 | Severe phototoxic burn following celery ingestion.
A 65-year-old woman developed a severe, generalized phototoxic reaction following a visit to a suntan parlor.
History taking revealed that she had consumed a large quantity of celery root (Apium graveolens) 1 hour earlier.
With the use of thin-layer chromatography, ... | 16 |
2,846 | Bilateral sacroiliac joint fracture-dislocation: a case report.
Bilateral sacroiliac joint fracture-dislocation of the sacrum with displacement is a rare injury.
We found only four such injuries previously reported in the literature.
Nonoperative management in this case led to complete functional return and acceptab... | 20 |
3,220 | Management of premature removal of the percutaneous gastrostomy.
Percutaneous endoscopic gastrostomy (PEG) has become the preferred method of enteral access for nutritional support.
With increased use of this modality, complications are encountered more frequently.
Premature withdrawal, inadvertent removal of the ga... | 22 |
633 | Diastrophic dysplasia gene maps to the distal long arm of chromosome 5.
We have used polymorphic DNA markers to map the gene for a clinically well-characterized form of osteochondrodysplasia, diastrophic dysplasia (DD), an autosomal recessive disorder of unknown pathogenesis.
Linkage was analyzed in 13 families with ... | 4 |
1,806 | Respiratory muscle strength in congestive heart failure.
In experimental animals, conditions which drastically decrease cardiac output may reduce the strength and endurance of respiratory muscles leading to hypercapnic respiratory failure.
Because patients with chronic CHF have reduced cardiac output and vital capaci... | 13 |
773 | Assessment of functional gastrointestinal disease: the bowel disease questionnaire.
A need exists for a self-report questionnaire that reliably and accurately measures symptoms and that distinguishes patients with functional gastrointestinal disease from those with other conditions.
We have developed such an instrume... | 5 |
2,145 | Enhanced endogenous leukotriene biosynthesis in patients treated with granulocyte-macrophage colony-stimulating factor.
The hematopoietic cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) is being used in clinical trials for its potential in the treatment of hematopoietic insufficiency due to various ... | 14 |
728 | Healing or amelioration of esophagitis does not result in increased lower esophageal sphincter or esophageal contractile pressure [published erratum appears in Am J Gastroenterol 1991 Feb;86(2):253]
There is conflicting evidence regarding whether lower esophageal sphincter and esophageal contractile pressures are affe... | 5 |
1,250 | Histopathologic study of the Molteno glaucoma implant in three patients.
Three eyes with the Molteno glaucoma implant (one eye with epithelial downgrowth, one eye with iridocorneal endothelial syndrome, and one eye with aphakia and glaucoma) were enucleated two to six years after implantation.
Histopathologic examina... | 10 |
3,032 | Isoenzymes of aldehyde dehydrogenase in human lymphocytes.
The types of isozymes of aldehyde dehydrogenase (ALDH) present in human lymphocytes has been investigated using isoelectric focusing of polyacrylamide gels followed by substrate-specific staining.
Lymphocytes obtained from most individuals were found to conta... | 22 |
2,803 | Methylene chloride: report of five exposures and two deaths.
Five patients presented to the emergency department (ED) following exposure in an enclosed space to methylene chloride (dichloromethane), used for removing paint.
Two workers and three rescuers were involved.
Two rescuers complained only of dizziness and m... | 20 |
1,786 | Surgical repair of postinfarction ventricular septal defect.
Thirty-one patients underwent repair of postinfarction ventricular septal defect (VSD) from 1980 to 1989.
All patients were in New York Heart Association functional class IV, and 15 of them were in cardiogenic shock when operated on.
Coronary arteriography... | 13 |
2,811 | Brief intervention strategies for harmful drinkers: new directions for medical education.
Recent advances in the technology of behavioural interventions for harmful drinkers have created a new role for clinical practice and new challenges for medical education.
Several reports from expert committees have recommended ... | 20 |
61 | Comparison of species distribution and antimicrobial susceptibility of aerobic actinomycetes from clinical specimens.
To compare the species distribution and antimicrobial susceptibility of aerobic actinomycetes, we evaluated 366 isolates referred to the Centers for Disease Control from October 1985 through February 1... | 0 |
3,332 | Development of a soft, pliable, slow heparin release venous graft.
To prevent their collapse, a certain amount of stiffness is generally required for prosthetic venous grafts, so EPTFE grafts have been used.
However, the native vein is pliable without any stiffness.
We developed a soft and pliable graft that can mai... | 22 |
2,657 | Evaluation of the efficacy and cost effectiveness of health education methods to increase medication adherence among adults with asthma.
We randomized 135 adult asthma patients to a control group, and 132 patients to an experimental group which received a special health education intervention.
Four adherence measures... | 19 |
406 | Interventional radiology of the biliary tract. Intraductal radiation.
One palliative method of treating patients with a high duct cholangiocarcinoma is the use of 192Ir wire.
This is placed through the tumor, which has been previously intubated, and delivers a high local dose of radiation.
The mean survival time in ... | 3 |
2,216 | Autosomal dominant retinitis pigmentosa: absence of the rhodopsin proline----histidine substitution (codon 23) in pedigrees from Europe.
In exon 1 at codon 23 of the rhodopsin gene, a mutation resulting in a proline-to-histidine substitution has previously been observed in approximately 12% of American autosomal domin... | 15 |
1,077 | Patellar resurfacing in total knee arthroplasty.
Technical errors in patellar resurfacing at the time of total knee arthroplasty (TKA) are responsible for many of the complications that affect the patellofemoral joint.
Instability, patellar fracture, and wear of metal-backed patellar implants are significantly affect... | 9 |
2,843 | Basophil releasability in severely burned patients.
Thermal injury is known to induce dysregulation of the immune system; however, the precise mechanisms have to be clarified.
We investigated the histamine release of basophil granulocytes from severely burned patients (n = 12) after stimulation with anti-IgE or the C... | 20 |
1,234 | Community hospital carotid endarterectomy in patients over age 75.
We compared the prevalence of stroke and death in 133 patients aged 75 and older in whom 170 carotid endarterectomies were performed with that in 501 patients less than age 75 in whom 640 carotid endarterectomies were performed.
There were three strok... | 9 |
2,470 | The need for accurate nutrition survey methodology: the South Carolina experience.
Assessment of two nutrition-related risk factors, obesity and fat intake, was completed on a representative sample of South Carolina adults.
Obesity estimates determined from self-reported heights and weights were less than prevalences... | 17 |
1,130 | Late juvenile-onset Krabbe's disease.
Krabbe's disease is an autosomal recessive leukodystrophy characterized by a lack of galactocerebroside beta-galactosidase activity.
In contrast to the classic early infantile-onset form of Krabbe's disease, less recognized, late-onset variants exist.
The authors present a case ... | 9 |
79 | Immunogenicity in animals of a polysaccharide-protein conjugate vaccine against type III group B Streptococcus.
The native capsular polysaccharide of type III group B Streptococcus elicits a specific antibody response in only 60% of nonimmune human subjects.
To enhance the immunogenicity of this polysaccharide, we co... | 0 |
1,280 | Immunohistologic study of epiretinal membranes in proliferative vitreoretinopathy.
We performed an immunohistologic study on 11 specimens of epiretinal membranes surgically obtained from patients who had rhegmatogenous retinal detachment with proliferative vitreoretinopathy.
Immunostaining procedures were used to ide... | 10 |
2,357 | Development of IDDM after donating kidney to diabetic sibling.
The goal of this study was to describe a patient who developed insulin-dependent diabetes mellitus (IDDM) after donating a kidney to his sibling and to suggest a possible solution to prevent such an occurrence.
A 42-yr-old man was found to have islet cell... | 17 |
457 | The Cancer Prevention Reminder System.
The Cancer Prevention Reminder System is a computer-based system designed to increase the delivery of periodic health maintenance procedures.
The program provides printed reminders that identify patients' overdue procedures, prints summary reports of the percentage of patients w... | 3 |
2,223 | Parenchymal and vascular magnetic resonance imaging of the brain after extracorporeal membrane oxygenation.
Three-dimensional (volume) magnetic resonance angiography is a new and noninvasive method for imaging the intracranial vasculature.
The combination of magnetic resonance angiography and conventional magnetic re... | 15 |
634 | Fructose-induced aberration of metabolism in familial gout identified by 31P magnetic resonance spectroscopy.
The hyperuricemia responsible for the development of gouty arthritis results from a wide range of environmental factors and underlying genetically determined aberrations of metabolism.
31P magnetic resonance ... | 4 |
3,042 | Pharmacokinetics of paracetamol after cardiac surgery.
Plasma concentration was measured after rectal and nasogastric administration of paracetamol 15 mg/kg to 28 febrile children aged between 9 days to 7 years who had undergone cardiac surgery.
After equivalent doses, rectal administration in neonates and children o... | 22 |
119 | Immunocytochemical analysis of lymph node aspirates in patients with human immunodeficiency virus infection.
Thirty four patients positive for human immunodeficiency virus (HIV) who had lymphadenopathy were investigated using fine needle aspiration.
Cytological analysis included immunocytochemical investigation with ... | 1 |
741 | Enteroglucagon and peptide Y-Y response after construction of a pelvic reservoir in humans.
The results of an investigation of plasma levels of gastrointestinal hormones in patients after the construction of a pelvic reservoir are reported.
Enteroglucagon (EG) and peptide tyrosine-tyrosine (PYY), two hormones believe... | 5 |
1,270 | Assessment of tear drainage after canalicular obstruction using fluorescein dye disappearance.
Assessment of tear drainage impairment after monocanalicular obstruction can be difficult.
The authors used fluorescein dye disappearance to evaluate tear drainage after experimental obstruction of upper, lower, neither, or... | 10 |
2,683 | Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications.
From an extensive serial magnetic resonance imaging (MRI) study in multiple sclerosis (MS) we have identified 4 cases in which disruption of the blood-brain barrier, ... | 19 |
1,171 | Ultrasonography and magnetic resonance imaging in Leigh disease.
An infant with Leigh disease, who was the younger sister of a similarly affected infant, had been examined before the onset of the disease.
Ultrasonography revealed hyperechoic lesions in the putamen and caudate nucleus during the preclinical stage.
At... | 9 |
2,303 | Psoriasis: the application of genetic technology and mapping.
Recent progress in molecular genetics has led to the creation of a map of the human genome utilizing RFLP.
Given a sufficient family structure, genetic diseases can now be placed on this map.
Genetic studies of psoriasis can both help resolve and be confo... | 16 |
554 | Cryoprobe as a "handle" for resection of metastatic liver tumors.
Resection of metastatic liver tumors can be a difficult and risky procedure.
Using a cryoprobe as a "handle" can greatly facilitate resection by providing a taut surface for transection and improving visualization of ductal and vascular structures.
In... | 3 |
2,550 | In vitro and in vivo testing of an electrocatalytic glucose sensor.
A prerequisite for the development of an implantable artificial pancreas is the availability of a stable, long-life glucose sensor.
Platinum (Pt) catalyzed electrodes have been demonstrated in vitro to show high sensitivity to glucose and long cycle ... | 18 |
3,155 | Does indomethacin alter the hemodynamic response to magnesium sulfate infusion and hemorrhage in gravid ewes?
The purpose of this study was to determine whether indomethacin alters the maternal and fetal hemodynamic response to magnesium sulfate (MgSO4) infusion and hemorrhage in gravid ewes.
We studied seven chronic... | 22 |
850 | Diagnosing periodontal diseases.
At present, the diagnosis of periodontal disease requires a clinical evaluation of the patient including visual findings, the use of the periodontal probe, and radiographs.
No test is available to evaluate disease activity.
In specific cases, adjunctive procedures may also be useful.... | 6 |
2,128 | Prevalence of Raynaud phenomenon in the adult population of South Carolina.
A prevalence estimate for Raynaud phenomenon among adult residents of South Carolina was based on data obtained from respondents in a statewide health survey, followed by face-to-face interviews and clinical screening for Raynaud phenomenon, u... | 13 |
2,589 | Multiple sclerosis is prevalent in the Zoroastrians (Parsis) of India.
Using Schumacher's classification, we determined the prevalence rate of clinically definite multiple sclerosis (MS) in the distinct but tiny Zoroastrian (largely Parsi) community in the adjacent cities of Bombay (latitude, 18.55 degrees) and Poona ... | 19 |
2,300 | Lymphocyte trafficking in psoriasis: a new perspective emphasizing the dermal dendrocyte with active dermal recruitment mediated via endothelial cells followed by intra-epidermal T-cell activation.
Prominent within the inflammatory infiltrate of psoriasis are HLA-DR positive T lymphocytes and factor XIIIa positive der... | 16 |
915 | Trimming of the inferior turbinates: a prospective long-term study.
The aim of this study was to determine whether the initial benefits of radical trimming and anterior trimming of the inferior turbinates on nasal airflow persisted in the long term.
Radical trimming significantly reduced nasal resistance at 2 months ... | 7 |
1,825 | The effect of enoximone and dobutamine on hemodynamic performance after open heart surgery. A clinical comparison.
In a prospective, randomized study the phosphodiesterase inhibitor enoximone was compared to dobutamine after open heart surgery.
In either group 25 patients were treated with enoximone and dobutamine, r... | 13 |
3,170 | MyoD induces growth arrest independent of differentiation in normal and transformed cells.
MyoD is a gene involved in the control of muscle differentiation.
We show that MyoD causes growth arrest when expressed in cell lines derived from tumors or transformed by different oncogenes.
MyoD-induced growth inhibition wa... | 22 |
151 | Studies in owl monkeys leading to the development of a synthetic vaccine against the asexual blood stages of Plasmodium falciparum.
During the development of a synthetic vaccine for human use against the asexual blood stages of Plasmodium falciparum, monkey trials were performed to assess safety, immunogenicity, and p... | 2 |
3,161 | Histologic evaluation of the width of soft tissue necrosis adjacent to carbon dioxide laser incisions.
This study evaluated the width of tissue necrosis lateral to carbon dioxide laser incisions on human intraoral excisional biopsy specimens.
Measurements were made on specimens including epithelium, muscle, dense and... | 22 |
836 | Plasma fatty acid profile in advanced cirrhosis: unsaturation deficit of lipid fractions.
Fatty acid (FA) profile of plasma total lipids, phospholipids (PL), cholesteryl esters (CE), and triglycerides (TG) were measured in 101 patients with advanced liver cirrhosis and in 44 age- and sex-matched healthy controls.
Pla... | 5 |
1,308 | The absence of nephrotoxicity and differential nephrotoxicity between tobramycin and gentamicin.
We conducted a prospective, double-blind, randomized trial of gentamicin and tobramycin to evaluate differences in nephrotoxicity.
We evaluated levels of creatinine, creatinine clearance, beta 2-microglobulin, and N-acety... | 11 |
354 | Implementation of cancer prevention guidelines in clinical practice.
Data from several sources, including consumer surveys, physician surveys, and medical record audits, indicate that consumers do not receive cancer screening tests as recommended by the National Cancer Institute, the American Cancer Society, and the U... | 3 |
2,399 | S-antigen. Identification of human T-cell lymphocyte proliferation sites.
Immune responses to normal retinal proteins, including S-antigen, have been demonstrated in patients with a variety of retinal disorders, as well as in those who have received panretinal laser photocoagulation.
T-cell lymphocytes (T cells) have... | 17 |
3,041 | Recurrent cyanotic episodes with severe arterial hypoxaemia and intrapulmonary shunting: a mechanism for sudden death
The pathophysiology of recurrent cyanotic episodes has been investigated in 51 infants and children.
Episodes began at a median age of 7 weeks (range 1 day to 22 months, 39 at less than 4 months).
T... | 22 |
165 | Genotypic characterization of centrocytic lymphoma: frequent rearrangement of the chromosome 11 bcl-1 locus.
Centrocytic lymphomas are defined in the Kiel classification as B-cell lymphomas composed exclusively of cells resembling cleaved follicular center cells (FCC).
These lymphomas have been shown to be histologic... | 3 |
3,228 | Aortic occlusion and vascular isolation allowing avascular hepatic resection.
Occlusion of the supraceliac abdominal aorta and hepatic vascular isolation were employed in a series of 15 patients as a definitive method to allow avascular hepatic resection.
The series was compared with an earlier group of patients trea... | 22 |
2,233 | Neonatal ethics: development of a consultative group.
Experience of a neonatal ethics advisory group in a tertiary care setting was reviewed to identify which aspects of the experience have been most valuable in the development of a consultative group.
Consultations were requested for 31 patients seen from August 198... | 15 |
1,126 | The opposite pupil in herniation.
I serially examined the pupil opposite the one already enlarged from transtentorial herniation in 13 patients.
The main abnormalities, stereotyped in most patients, were an initially diminished light reaction with a 2.5- to 4-mm-diameter pupil, followed by slight reduction in size, a... | 9 |
855 | Dental implants used for periodontal patients.
For those performing implant treatment, continued research and reports of long-term successful results are essential to evaluating the validity of implants, especially when variables such as design and surface treatment are introduced.
The dental profession has enthusias... | 6 |
2,343 | Specificity of anti-Scl-70 antibodies in scleroderma: increased sensitivity of detection using purified DNA topoisomerase I from calf thymus.
A large scale purification of DNA topoisomerase I from calf thymus was obtained using the combinations of 62% ammonium sulfate precipitation, Biorex 70, hydroxylapatite and phen... | 16 |
2,325 | Spinal synovial cyst: case report using magnetic resonance imaging.
The case of a 65-year-old woman who developed a spinal synovial cyst at the L4-5 disk space is reported.
Her clinical signs and symptoms are presented.
A comparison among her preoperative myelogram, computed tomography scan, and magnetic resonance i... | 16 |
1,115 | Responses of intercostal muscle biopsies from normal subjects and patients with myasthenia gravis.
In order to evaluate the mechanisms of weakness in muscles of patients with myasthenia gravis (MG), intercostal muscle biopsies were obtained from 9 normal subjects and 6 MG patients, and the compound muscle action poten... | 9 |
3,302 | Effect of indomethacin on pain relief after thoracotomy.
The effect of indomethacin on postoperative pain was studied in 60 adult patients undergoing thoracotomy in a prospective, randomized, double-blind manner.
Patients receiving indomethacin required significantly less opioid after operation and had significantly ... | 22 |
1,447 | Immunotherapy of murine bladder cancer by irradiated tumor vaccine.
This investigation explored the efficacy of irradiated autologous mouse bladder tumor (Ir-MBT2) as an active specific immunotherapeutic agent and as adjuvant therapy with Bacillus Calmette-Guerin (BCG) against a subcutaneously transplanted murine blad... | 11 |
2,647 | Epidemiology of cytomegalovirus infections.
The determinants of cytomegalovirus (CMV) infection and disease can now be understood from studies of newborns, recipients of organ or bone marrow transplants, subjects infected with human immunodeficiency virus, and recipients of blood transfusions.
CMV is transmitted to t... | 19 |
2,065 | Elevated plasma noradrenaline concentrations in patients with low-output cardiac failure: dependence on increased noradrenaline secretion rates.
1.
Plasma noradrenaline concentrations are elevated in patients with congestive heart failure; however, the pathogenesis of these elevated noradrenaline levels is controvers... | 13 |
2,628 | Serial studies of evoked potentials and circulating lymphocyte subsets for multiple sclerosis: attempts to monitor progress.
A concurrent change in evoked potential measurements and quantitation of circulating T-suppressor (CD8) lymphocyte subpopulations might indicate increased subclinical disease activity.
Eight un... | 19 |
1,847 | Relation between beta-adrenergic blocker use, various correlates of left ventricular function and the chance of developing congestive heart failure. The Multicenter Diltiazem Post-Infarction Research Group.
This study examined the relations among beta-adrenergic blocker use, various correlates of left ventricular func... | 13 |
655 | Magnetic resonance imaging and the nonoperative treatment of spinal epidural abscess.
This report describes three patients with spinal epidural abscess diagnosed by magnetic resonance imaging and treated nonoperatively.
Prior to treatment, one patient was neurologically intact, one patient demonstrated a moderate neu... | 4 |
3,040 | Meropenem pharmacokinetics and penetration into an inflammatory exudate.
The pharmacokinetics and penetration into a cantharidine-induced inflammatory exudate of meropenem was studied in six volunteers following a single 1-g intravenous dose.
Concentrations in plasma, urine, and the inflammatory exudate were determin... | 22 |
1,739 | Vascular and calcemic effects of plasma of spontaneously hypertensive rats.
Circulating substances that increase intracellular calcium, and other circulating substances that increase blood pressure, have been described in hypertensive animals and humans.
In this study, we report the existence of a factor of the plasm... | 13 |
1,604 | Early and late effects of captopril treatment after large myocardial infarction in rats.
The early (after 21 days) and late (after 4 months) effects of continuous treatment with captopril on left ventricular performance, weight and volumes were studied in rats with myocardial infarction.
Early effects were examined i... | 13 |
1,633 | Parental history is an independent risk factor for coronary artery disease: the Framingham Study.
Family history of CAD, defined as parental death by CAD, was found to be a significant independent predictor of CAD in a logistic regression model controlling for standard risk factors and length of follow-up among the 52... | 13 |
3,189 | Usefulness of combined propranolol and verapamil for evaluation of surgical ablation of accessory atrioventricular connections in patients without structural heart disease.
Successful surgical ablation of atrioventricular (AV) accessory connections may be confirmed during postoperative electrophysiologic testing by th... | 22 |
2,778 | Inpatient treatment of employed alcoholics: a randomized clinical trial on Hazelden-type and traditional treatment.
The first randomized clinical trial on the Hazelden-type of treatment showed that this AA-oriented treatment for alcoholism can result in significant improvement in drinking behavior as compared to a mor... | 20 |
2,875 | Simultaneous reconstruction of cervical soft tissue and esophagus with a gastro-omental free flap.
A microvascular transfer of gastric tube and omentum was used to simultaneously reconstruct cervical soft-tissue and esophageal defects in five patients.
All patients had previous high-dose radiation and multiple flap r... | 20 |
2,616 | The use of antihistamines in the prevention and treatment of anaphylaxis and anaphylactoid reactions.
The pathophysiologic effects of histamine in anaphylaxis have been shown to be mediated through H1 and H2 receptors, individually and in combination.
H1 receptors mediate coronary artery vasoconstriction, wheezing, c... | 19 |
2,305 | Sodium lauryl sulphate for irritant patch testing--a dose-response study using bioengineering methods for determination of skin irritation.
The dose-response relationship in patch testing with sodium lauryl sulphate (SLS) was studied.
The irritant skin response was quantified by visual scoring as well as by the follo... | 16 |
1,161 | IgM deposits at nodes of Ranvier in a patient with amyotrophic lateral sclerosis, anti-GM1 antibodies, and multifocal motor conduction block.
We studied a patient with amyotrophic lateral sclerosis, multifocal motor conduction block, and IgM anti-GM1 antibodies.
A sural nerve biopsy demonstrated deposits of IgM at no... | 9 |
503 | Use of Mohs micrographic surgery to establish quantitative proof of heightened tumor spread in basal cell carcinoma recurrent following radiotherapy.
We compared 27 basal-cell carcinomas (BCCs) recurrent following radiotherapy and subsequently excised by Mohs micrographic surgery to a control group of BCCs recurrent f... | 3 |
3,222 | Hiccups and breathing in human fetuses.
Serial recording in 45 low risk fetuses throughout the second and third trimesters showed that hiccups were the predominant diaphragmatic movement before 26 weeks' gestational age and that there was a significant negative correlation with gestational age.
There was a pronounced... | 22 |
2,926 | Gasoline burns: the preventable cause of thermal injury.
Gasoline related burns are a significant cause of thermal injuries each year in the United States.
In this retrospective review of 1858 admissions to our Regional Burn Center from 1979 to 1988, 270 (14.5%) were persons with gasoline-related injuries.
Natural g... | 20 |
665 | The effects of parathyroid hormone (PTH) and PTH-related peptide on osteoclast resorption of bone slices in vitro: an analysis of pit size and the resorption focus.
The mechanism whereby PTH, a potent stimulator of bone resorption, may under certain circumstances exert anabolic effects on bone is not known, but it is ... | 4 |
3,282 | Adult height in boys and girls with untreated short stature and constitutional delay of growth and puberty: accuracy of five different methods of height prediction.
To determine how accurately several methods of height prediction estimate adult height, we compared height predictions calculated by the Bayley-Pinneau, R... | 22 |
2,698 | Biology of retroviruses. Detection, molecular biology, and treatment of retroviral infection.
Although human retrovirology can trace its roots to the early part of this century, it has been within the last decade that the field has seen its greatest advances, including the description of the first human retroviruses, ... | 19 |
470 | Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
Familial cancer syndromes have helped to define the role of tumor suppressor genes in the development of cancer.
The dominantly inherited Li-Fraumeni syndrome (LFS) is of particular interest because of the diversity of chi... | 3 |
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