Unnamed: 0 int64 0 3.36k | text stringlengths 220 2.92k | label int64 0 22 |
|---|---|---|
1,547 | Flow patterns in dilated cardiomyopathy: a pulsed-wave and color flow Doppler study.
In 48 patients with dilated cardiomyopathy, pulsed-wave and color Doppler examination were performed.
In addition, 14 normal patients served as control subjects.
Peak inflow velocity at the level of the mitral valve, middle left ven... | 13 |
49 | Tumor necrosis factor-alpha plays a role in host defense against Histoplasma capsulatum.
Tumor necrosis factor-alpha was detected in supernatants collected from BALB/c mouse peritoneal macrophages incubated continuously with Histoplasma capsulatum.
The levels of TNF alpha measured by actinomycin D bioassay peaked wit... | 0 |
763 | Rosacea and ulcerative colitis: a possible association.
Although rosacea was formerly believed to be associated with gastrointestinal upsets, no one any longer finds a significant association between rosacea and the intestinal tract.
We describe four patients with a combination of ulcerative colitis and rosacea.
In ... | 5 |
647 | Gallium nitrate for advanced Paget disease of bone: effectiveness and dose-response analysis.
OBJECTIVE: To evaluate whether a brief course of treatment with gallium nitrate can reduce biochemical parameters of accelerated bone turnover in patients with advanced Paget disease.
DESIGN: Unblinded trial, decreasing dose... | 4 |
1,839 | Efficacy of propafenone in preventing ventricular tachycardia: inverse correlation with rate-related prolongation of conduction time
The efficacy of propafenone in preventing induction of ventricular tachycardia was evaluated in 25 consecutive patients (mean age 62 +/- 8 years) with remote myocardial infarction who u... | 13 |
1,650 | Transient left ventricular filling abnormalities (diastolic stunning) after acute myocardial infarction.
A variety of experimental studies suggest that diastolic left ventricular (LV) function changes after acute myocardial infarction (AMI), but limited data exist on these changes in humans.
To assess diastolic filli... | 13 |
3,038 | Cochlear implant flap complications.
In a series of 52 patients who received cochlear implants, 4 patients suffered flap complications (7.7%).
The problems encountered involved the postauricular flap and were usually minor in nature.
None required explantation as a direct result of these complications.
Flap ischemi... | 22 |
1,287 | Possible significance of cilioretinal arteries in low-tension glaucoma.
Cilioretinal arteries arise from the short posterior ciliary artery circulation or directly from the choroidal circulation.
The presence of a cilioretinal artery may in compromised discs steal flow from the peripapillary circulation and account f... | 10 |
2,700 | Care of the infant born exposed to human immunodeficiency virus.
The expanding epidemic of HIV infection in reproductive-age women, the availability of antiretroviral therapy for children, and recommendations for increased case identification activities augur a time when more and more pediatricians are going to be cal... | 19 |
343 | Pediatric osteosarcoma: therapeutic strategies, results, and prognostic factors derived from a 10-year experience.
Ninety-eight pediatric patients were treated with three separate protocols (Treatment and investigation of Osteosarcoma [TIOS] I, II, and III) and 47 developed recurrent disease (metastases and/or local r... | 3 |
2,047 | Can heart failure be prevented, delayed, or reversed?
A review of the clinical course of chronic heart failure demonstrates that current outcomes remain highly unsatisfactory both in mortality and perhaps more important in morbidity.
The extraordinary satisfactory functional responses seen in patients who undergo car... | 13 |
2,604 | Non-Hodgkin's lymphoma in the elderly. I. Pathologic features at presentation.
The pathologic findings of 118 patients aged 70 years or older with non-Hodgkin's lymphoma (NHL) are reported.
These patients formed 27.2% of 433 consecutive cases of NHL seen in a single institution over a 5-year period.
Thirty-one of 43... | 19 |
1,717 | Liver transplantation with atrioatrial anastomosis for Budd-Chiari syndrome.
We report the case of a young woman with Budd-Chiari syndrome in whom mesentericoval shunt was first performed, followed by transcaval liver resection and hepatoatrial anatomosis 3 years later.
Liver transplantation became necessary 5 years ... | 13 |
1,705 | Underestimation of treatment effect in crossover trials.
In crossover trials each subject serves as his own control.
For the study of cardiovascular diseases such as hypertension and angina pectoria, properly designed crossover studies are preferred to parallel studies.
There is a considerable between-subject variab... | 13 |
3,023 | Sudden unexpected nocturnal death syndrome in the Mariana Islands.
Sudden unexpected nocturnal death syndrome (SUNDS) is a distinct clinical entity in previously healthy, young, Southeast Asian males.
It is well known in the Philippines and more recently recognized in the U.S.
by nonspecific autopsy findings, with n... | 22 |
2,192 | William Glenn lecture. The cavopulmonary shunt. Evolution of a concept.
A bold and imaginative development, the cavopulmonary anastomosis, appeared to originate in several centers almost simultaneously.
After extensive research on right heart bypass, Glenn was the first in North America to perform a successful experi... | 15 |
1,056 | Spectral electroretinography in thioridazine toxicity.
In three patients with thioridazine toxicity, the electroretinogram (ERG) to red light was found to be below the average normal range.
A significant increase in its amplitude appeared with cessation of therapy in two cases.
A further deterioration of the ERG amp... | 9 |
1,487 | Hyperemesis gravidarum as conversion disorder.
Psychosocial factors have long been believed to be important in the pathogenesis of emesis gravidarum (morning sickness) and hyperemesis gravidarum (HG).
Although this has been confirmed during extensive studies over the last 30 years, HG has never been described as a co... | 12 |
2,170 | Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease.
A membrane-bound cytochrome b, a heterodimer formed by a 91-kD glycoprotein (heavy chain) and a 22-kD polypeptide (light chain), is an esse... | 14 |
1,632 | Hypertensive heart disease: relationship of silent ischemia to coronary artery disease and left ventricular hypertrophy.
ECG evidence of silent ischemia occurs commonly in patients with systemic hypertension, but its relationship to left ventricular hypertrophy (LVH), large-vessel coronary artery disease (CAD), and ne... | 13 |
2,938 | Reporting of occupational injury and illness in the semiconductor manufacturing industry.
In the United States, occupational illness and injury cases meeting specific reporting criteria are recorded on company Occupational Safety and Health Administration (OSHA) 200 logs; case description data are submitted to partici... | 20 |
1,075 | Does primary fibromyalgia exist?
Twenty-one of 25 consecutive primary fibromyalgia or fibrositis patients, identified during a 5-year period in a tertiary care day-ward for pain syndromes, were re-examined.
Fifteen fulfilled criteria for fibromyalgia but unexpectedly, all cases had either psychiatric disturbance or ... | 9 |
1,861 | The costs of prevention.
A prevention program is cost-effective if it yields more health benefits than do alternative uses of health care resources.
Some prevention programs meet this standard: either they actually save more health care resources than they utilize, or their net costs per healthy year of life gained a... | 13 |
3,108 | Maximal O2 uptake of in situ dog muscle during acute hypoxemia with constant perfusion.
We investigated the relationships among maximal O2 uptake (VO2max), effluent venous PO2 (PvO2), and calculated mean capillary PO2 (PCO2) in isolated dog gastrocnemius in situ as arterial PO2 (PaO2) was progressively reduced with mu... | 22 |
2,913 | Removal of blunt foreign bodies from the esophagus.
Historically, removal of blunt foreign bodies from the esophagus by esophagoscopy under general anesthesia has been considered to be relatively safe and effective.
In recent years, alternative techniques of blind removal with balloon catheters or bougies have been a... | 20 |
1,035 | Anencephaly: clinical determination of brain death and neuropathologic studies.
Twelve liveborn anencephalic infants were serially examined to determine if they would meet our clinical criteria for whole brain death within a 7-day period: Protocol 1 infants (6) received intensive care including intubation from birth; ... | 9 |
181 | Mucinous adenocarcinoma of the submandibular gland.
A rare tumor not easily classifiable among published histologic categories for salivary gland tumors is reported.
The neoplasm developed within the submandibular gland of a 78-year-old woman with invasion of the mandible and metastasis to regional lymph nodes.
Hist... | 3 |
2,359 | Sulfonylureas. Why, which, and how?
Although controversies remain as to the usefulness of sulfonylureas, most evidence is in favor of their use in many if not patients with non-insulin-dependent diabetes mellitus.
When used properly, sulfonylureas improve insulin secretion and action, and these effects may be maintai... | 17 |
1,506 | Continuous or interrupted fascial closure: a prospective evaluation of No. 1 Maxon suture in 402 gynecologic procedures.
During a 14-month period of using a long-term absorbable suture (No.
1 Maxon), 402 patients were entered into a prospective, randomized trial of fascial closure.
Patients were randomized between a... | 12 |
3,171 | Role of tryptophan repeats and flanking amino acids in Myb-DNA interactions.
The c-myb protooncogene codes for a sequence-specific DNA-binding protein that appears to act as a transcriptional regulator and is highly conserved through evolution.
The DNA-binding domain of Myb has been shown to contain three imperfectly... | 22 |
2,456 | Physical growth and development of children with type 1 glycogen-storage disease: comparison of the effects of long-term use of dextrose and uncooked cornstarch.
Thirteen patients with type 1 glycogen-storage disease (GSD-1) were studied to compare the effects on biochemical control and growth of 2 y of therapy with i... | 17 |
1,462 | Preoperative evaluation of serum CA 125, TAG 72, and CA 15-3 in patients with endometrial carcinoma.
We evaluated 109 women with endometrial carcinoma to determine the accuracy of preoperative tumor-associated antigen levels (CA 125, CA 72, CA 15-3) for prediction of extrauterine disease and whether TAG 72, CA 15-3, o... | 12 |
2,815 | Continuous suprascapular nerve block for analgesia of scapular fracture.
Fracture of the scapular is uncommon but painful.
A case is described in which a comminuted scapular fracture was treated with a continuous suprascapular nerve block.
With the patient lying supine an epidural needle was directed towards the sca... | 20 |
1,433 | Chronic nightly tidal peritoneal dialysis.
Nightly tidal peritoneal dialysis (NTPD) is a technique in which, after an initial fill of the peritoneal cavity, only a portion of dialysate is rapidly cycled.
Five anuric, stable, PD patients entered a 4 month study to determine the NTPD session length necessary for clinic... | 11 |
708 | Gallbladder mucin as a pronucleating agent for cholesterol monohydrate crystals in bile.
Mucin is a densely glycosylated macromolecule secreted by the gallbladder epithelium as the principal constituent of gallbladder mucus.
Hypersecretion of gallbladder mucus occurs in response to a lithogenic diet in experimental a... | 5 |
706 | Biliary cholesterol transport and precipitation: introduction and overview of conference.
Cholesterol is secreted into bile as cholesterol-phospholipid vesicles.
The cholesterol and phospholipid are subsequently exposed to the bile salts contained in the bile, which leads to the process of micellation.
Two situation... | 5 |
1,173 | The use of obstetric analgesia in Sweden 1983-1986
The use of obstetric analgesia was investigated in a Swedish population-based prospective study of 335,207 births, which represents almost all women who had vaginal deliveries in Sweden between 1983 and 1986.
Lumbar epidural analgesia (EDA) was used in 16%, paracerv... | 9 |
3,195 | Recombination between two 14-bp homologous sequences as the mechanism for gene deletion in factor IX Seattle 1.
Factor IXSeattle 1 is a 10-kb intragenic deletion identified in a family that has hemophilia B.
By sequencing across the site of the deletion, we discovered at the deletion junction a 13-bp sequence (5' .
... | 22 |
3,334 | Functional heart replacement with the spindle pump: first results.
The spindle pump is a nonpulsatile blood pump with a double function, i.e., it works centrifugally and represses simultaneously.
The first experiences with this type of pump used as a biventricular assist device in four short-term animal experiments (... | 22 |
82 | Postneonatal mortality in Norway: a study of recent trends and comparison with other mortality rates in Norwegian children.
Postneonatal mortality in Norway decreased rapidly from 1956 to 1980 but subsequently remained stable.
In recent years the postneonatal death rate appears to be increasing, primarily due to grea... | 0 |
516 | Cholangiocarcinoma.
The diagnosis of cholangiocarcinoma can now be made with greater rapidity and accuracy.
In the clinical setting of obstructive jaundice, a CT scan or sonogram may suggest cholangiocarcinoma if dilated intrahepatic ducts are seen with a nondilated extrahepatic biliary tree.
The diagnosis is confir... | 3 |
2,500 | Management of "brittle" diabetes with a preprogrammable implanted insulin pump delivering intraperitoneal insulin.
OBJECTIVE--Glycaemic control in a young woman with "brittle" diabetes.
DESIGN--Use of a preprogrammable fully implanted pump (Infusaid) to deliver insulin intraperitoneally at variable rates, giving a to... | 17 |
1,061 | Slow release carbamazepine in treatment of poorly controlled seizures.
Thirty three children with poorly controlled epilepsy, and six new patients, were treated with slow release carbamazepine.
Twelve of the former had a reduction in the number of seizures of more than half, and 10 had fewer side effects.
Three of t... | 9 |
290 | Multiple spinal metastases from paraganglioma.
Isolated vertebral body metastases from paraganglioma are exceedingly rare.
They have been reported to occur in the presence of active primary tumor in the neck, local recurrence, or widespread metastases.
A unique case of carotid body tumor (paraganglioma) is reported ... | 3 |
2,372 | Differences in lipoprotein subfraction composition and distribution between type I diabetic men and control subjects.
Subfractions of very-low-density and low-density lipoproteins were examined in 10 male normolipidemic type I (insulin-dependent) diabetic patients before and after improvement of metabolic control and ... | 17 |
2,388 | Assessment of cardiac function in patients who were morbidly obese.
Cardiac function of 30 patients who were morbidly obese was studied before bariatric surgery.
Twelve patients were studied 13 +/- 4 months after surgery.
These patients had a mean age of 37.1 +/- 2.9 years and a body mass index of 50.0 +/- 1.4 kg/m2... | 17 |
1,225 | Health locus of control, gender differences and adjustment to persistent pain.
Locus of control (LOC) beliefs, long thought important in adjustment to persistent pain, were studied among 160 subjects (67 males and 93 females) referred to a comprehensive pain rehabilitation program.
The subscale structure of the Multi... | 9 |
1,377 | Cell injury associated calcium oxalate crystalluria.
Renal tubular cell damage, resulting in membranuria, was induced by the administration of subcutaneous gentamicin to male Sprague-Dawley rats.
One group of rats received gentamicin only, while a second group was given gentamicin plus ethylene glycol in drinking wat... | 11 |
1,015 | Mucosal thickening on sinus X-rays and its significance.
Mucosal thickening is commonly seen on X-rays of the paranasal sinuses taken in the ENT department.
This sometimes leads to a sinus washout, which is clear, even though the X-rays were strongly suggestive of disease.
This paper examines the prevalence of sinus... | 8 |
1,435 | Clinical effects of a polyethylene glycol grafted cellulose membrane on thrombogenicity and biocompatibility during hemodialysis.
The biocompatibility and thrombogenicity of polyethylene-glycol (PEG)-grafted cellulose hemodialysis (HD) membranes (PEGC) were investigated in cross-over HD of five HD patients with ordina... | 11 |
1,304 | Analysis of sperm function in globozoospermia: implications for the mechanism of sperm-zona interaction.
The globozoospermic condition has provided a unique opportunity to determine how the abnormal mitochondrial organization and acrosomal loss associated with this syndrome, influence sperm function.
Despite the abno... | 11 |
2,108 | Increase of intraplatelet free calcium ion during extracorporeal circulation with a hollow fiber oxygenator: arterial filter and dynamics of platelet thrombosis on oxygenator and filter in a pig model.
Intraplatelet free calcium (IPFC) ions provide a common pathway for platelet activation leading to thrombosis and emb... | 13 |
2,021 | Clinical antecedents to in-hospital cardiopulmonary arrest.
While the outcome of in-hospital cardiopulmonary arrest has been studied extensively, the clinical antecedents of arrest are less well defined.
We studied a group of consecutive general hospital ward patients developing cardiopulmonary arrest.
Prospectively... | 13 |
582 | Association between extent of colonic mucosal sialomucin change and subsequent local recurrence after curative excision of primary colorectal cancer.
Two interrelated studies were carried out to determine whether extent of sialomucin change adjacent to a primary colorectal carcinoma predicted local tumour invasiveness... | 3 |
1,090 | Serious migraine: a study of some epidemiological aspects.
Data are scant concerning some epidemiological aspects of those severe headaches which cause serious personal and economic morbidity.
Our purpose was to study the incidence and other epidemiological features of patients suffering from severe migraine exacerba... | 9 |
979 | Effects of prostaglandin E1 on platelet attenuation of oxidant-induced edema in isolated rabbit lungs.
Numerous studies suggest that platelets may contribute to preservation of normal endothelial cell permeability in models of lung injury.
We have previously shown that washed human platelets prevent xanthine oxidase-... | 7 |
1,814 | Characteristics of biliary lipid metabolism after liver transplantation.
Biliary lipid metabolism was studied after 10 liver transplantations with continuous drainage of bile.
Within 3 wk after transplantation, the new liver produced bile with concentrations of biliary lipids in agreement with those reported for T-tu... | 13 |
1,176 | Early cerebral infarction: gadopentetate dimeglumine enhancement
Gadopentetate dimeglumine was administered prospectively to 50 patients who presented for magnetic resonance (MR) imaging within 2 weeks after a cortical cerebral infarction.
Twenty-two patients (44%) were imaged within 3 days after clinical ictus.
Ab... | 9 |
3,138 | Outcome of renal transplantation after urinary diversion and enterocystoplasty: a retrospective, controlled study.
A total of 17 patients with intestinal urinary diversion of enterocystoplasty underwent renal transplantation between 1970 and 1988.
Patient age ranged from 4 to 35 years (mean age 20 years).
The patien... | 22 |
1,010 | Unterberger stepping test: a useful indicator of peripheral vestibular dysfunction?
Deviation of gait in a stepping test has been proposed as a useful indicator of peripheral labyrinthine dysfunction.
A prospective study of 26 patients suspected of having uncompensated peripheral labyrinthine dysfunction and 49 norma... | 8 |
1,555 | Geographical clustering of risk factors and lifestyle for coronary heart disease in the Scottish Heart Health Study.
A large cross sectional study, the Scottish Heart Health Study, of 10,359 men and women from 22 districts of Scotland was undertaken to try to explain the geographical variation of coronary heart diseas... | 13 |
2,706 | Histopathologic, immunophenotypic, and genotypic analysis of Ki-1 anaplastic large cell lymphomas that express histiocyte-associated antigens.
CD30/Ki-1 antigen expression in 243 cases of malignant lymphomas was examined using Ber-H2 monoclonal antibody.
Among them 20 cases were categorized as Ki-1 anaplastic large c... | 19 |
408 | Survey of Alabama physicians' use of mammography, 1989.
In early 1989 we surveyed by questionnaire Alabama primary care physicians (N = 1800) concerning their attitudes toward and use of mammography.
There were 681 respondents (37.8%).
The majority (83%) recommend mammograms for their patients according to the Ameri... | 3 |
2,887 | Relationship of oxygen dose to angiogenesis induction in irradiated tissue.
This study was accomplished in an irradiated rabbit model to assess the angiogenic properties of normobaric oxygen and hyperbaric oxygen as compared with air-breathing controls.
Results indicated that normobaric oxygen had no angiogenic prope... | 20 |
2,280 | Prolonged remission after cyclosporine therapy in pemphigus vulgaris: report of two young siblings.
We report the clinical evolution of two young siblings with severe pemphigus vulgaris treated with cyclosporine for 30 and 12 months, respectively.
One was resistant to treatment with high-dose corticosteroids and azat... | 16 |
2,895 | Management of tracheobronchial foreign bodies in children: an update.
Tracheobronchial foreign bodies continue to be a source of morbidity and mortality in the pediatric population.
Technical advances in anesthesia and equipment have made the removal of these troublesome objects more feasible.
Diligence must still b... | 20 |
2,848 | Organ injury scaling, II: Pancreas, duodenum, small bowel, colon, and rectum.
The Organ Injury Scaling (O.I.S.) Committee of the American Association for the Surgery of Trauma (A.A.S.T.) has been charged to devise injury severity scores for individual organs to facilitate clinical research.
Our first report (1) addre... | 20 |
1,344 | Hypophosphatemia in infants on continuous ambulatory peritoneal dialysis.
Three infants with irreversible renal failure and treated with continuous ambulatory peritoneal dialysis (CAPD) developed hypophosphatemia.
In one of them rachitic lesions were observed on X-ray and bone biopsy showed osteomalacic osteodystroph... | 11 |
1,327 | The elderly on dialysis: some considerations in compliance.
Compliance with scheduled treatments, dietary and fluid restrictions, and multiple medications is an important component in the care and well-being of end-stage renal disease (ESRD) patients.
Given the rigorus and complex demands of dialysis, it is important... | 11 |
24 | In vitro susceptibility of Xanthomonas (Pseudomonas) maltophilia to newer antimicrobial agents.
The susceptibilities of 45 clinical and 3 environmental isolates of Xanthomonas maltophilia to 14 antimicrobial agents was determined by broth microdilution.
The newer quinolones PD117596, PD117558, PD127391, A-56620, amif... | 0 |
1,819 | Clinical controversies surrounding thrombolytic therapy in acute myocardial infarction.
The treatment of acute myocardial infarction has changed tremendously in the past decade because thrombolytic therapy has become the treatment of choice for the patient with acute myocardial infarction.
Although many issues have b... | 13 |
1,723 | Ventricular arrhythmias in hypertensive left ventricular hypertrophy. Relationship to coronary artery disease, left ventricular dysfunction, and myocardial fibrosis.
Ventricular arrhythmias occur with increased frequency in hypertensive patients with left ventricular hypertrophy (LVH).
The relationships, however, bet... | 13 |
235 | Selenium. Nutritional, toxicologic, and clinical aspects
Despite the recent findings of environmental contamination, selenium toxicosis in humans is exceedingly rare in the United States, with the few known cases resulting from industrial accidents and an episode involving the ingestion of superpotent selenium supple... | 3 |
1,613 | Fate of patients undergoing transluminal angioplasty for lower-limb ischemia.
A prospective study of 370 patients who underwent 500 percutaneous transluminal angioplasties (PTAs) for lower-limb ischemia over a 7-year period was performed.
A 97% follow-up rate was achieved.
The first PTA was successful in 188 patient... | 13 |
397 | Adult T-cell leukemia-derived factor/thioredoxin, produced by both human T-lymphotropic virus type I- and Epstein-Barr virus-transformed lymphocytes, acts as an autocrine growth factor and synergizes with interleukin 1 and interleukin 2.
Interleukin 1 (IL-1) has been obtained from the Epstein-Barr virus-infected B-lym... | 3 |
2,531 | Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects.
Although minimal model analysis of frequently sampled iv glucose tolerance tests (FSIGTs) to measure insulin sensitivity is well recognized, application has been limited by the need for endogenous insulin sec... | 18 |
2,844 | Studies on B-lymphocyte dysfunctions in severely burned patients.
We studied in vitro functional parameters of peripheral blood B-lymphocytes from severely burned patients (n = 10; burn injuries ranging from 25 to 72% TBSA).
While the number of B-cells remained unchanged, B-cell proliferation induced by Staphylococcu... | 20 |
317 | Transthyretin receptors on human astrocytoma cells.
Transthyretin (TTR), a transport protein for T4 and retinol-binding protein, is the principal T4-binding protein of cerebrospinal fluid.
Its function in regard to the delivery of its ligands and in other respects is unclear.
The binding of [125I] TTR to cultured hu... | 3 |
278 | Premorphological metabolic changes in human breast carcinogenesis.
Malignant breast tissue is characterized by morphological and metabolic changes when compared with normal breast tissue.
In this study, the cytochemical measurement of glucose-6-phosphate dehydrogenase (G6PD) activity was used to detect abnormal metab... | 3 |
945 | The contributions of John B. Murphy to thoracic surgery.
John B.
Murphy was a prominent surgeon who lived in Chicago from the 1880s until his death in 1916.
During his career, he was associated with both Rush Presbyterian and Northwestern Medical Schools.
He was responsible for popularizing the use of an artificial... | 7 |
2,639 | Pediatric acquired immunodeficiency syndrome: an unusually high incidence of twinning.
Surveillance data on incidence of twins among reported cases of pediatric AIDS in New York City are presented.
Most pairs are concordant for HIV infection.
Three discordant pairs have been described elsewhere.
Possible reasons fo... | 19 |
3,271 | Liver transplantation: the shadow side.
For a relatively large number of patients with liver disease, a liver transplant does not always provide a successful solution.
What does confrontation with this modern technology mean for those involved? We interviewed 30 relatives of patients who had died after they had been ... | 22 |
1,923 | Long-term effect of mexiletine on left ventricular function and relation to suppression of ventricular arrhythmia.
The effects of oral mexiletine on left ventricular (LV) ejection fraction (EF) and ventricular arrhythmias--and a possible relation between these effects--were evaluated during 3 months of therapy in 29 p... | 13 |
2,712 | The impact of HIV-related illness on employment.
We used structured telephone interviews to determine the extent of work loss following onset of symptoms, the interval between onset of symptoms and cessation of work, and the risk factors for work loss among 193 persons with symptoms of human immunodeficiency virus (HI... | 19 |
256 | Significance of positive margins in oral cavity squamous carcinoma.
Three hundred ninety-eight consecutive, previously untreated patients undergoing surgery for epidermoid carcinoma of the oral cavity from 1979 to 1983 were reviewed.
One hundred twenty-nine patients were classified as having positive surgical margins... | 3 |
410 | Time to recurrence varies inversely with thickness in clinical stage 1 cutaneous melanoma.
The thickness of a tumor has been identified as the principal prognostic factor in cutaneous malignant melanoma.
However, time to recurrence has not conclusively been related to thickness.
A retrospective study of 216 patients... | 3 |
568 | The role of attitudes, beliefs, and personal characteristics of Italian physicians in the surgical treatment of early breast cancer.
The influence of Italian physicians' attitudes, beliefs, and personal characteristics on medical decision making is examined in the case of surgical treatment of early breast cancer.
Re... | 3 |
1,897 | Clinical significance of simple heart rate-adjusted ST segment depression in supine leg exercise in the diagnosis of coronary artery disease.
To evaluate the clinical significance of simple heart rate-adjusted ST segment depression (delta ST/delta HR) in the diagnosis of coronary artery disease, 42 patients with stabl... | 13 |
1,466 | Maternal genetic effects on ethanol teratogenesis and dominance of relative embryonic resistance to malformations.
Maternal genetic factors and/or fetal genetic factors contribute to variations in response to prenatal alcohol exposure.
To assess the contribution of maternal genotype to ethanol teratogenesis, a recipr... | 12 |
1,742 | Contribution of calmodulin and protein kinase C to renin release in spontaneously hypertensive rats.
This study was designed to evaluate the contribution of calmodulin and protein kinase C to renin release from isolated glomeruli of spontaneously hypertensive rats (SHR, Okamoto and Aoki).
Male 7-week-old SHR and age-... | 13 |
671 | The molecular basis of hereditary 1,25-dihydroxyvitamin D3 resistant rickets in seven related families.
Hereditary 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] resistant rickets (HVDRR) is an autosomal recessive disease caused by target organ resistance to the action of 1,25(OH)2D3, the active form of the hormone.
The defe... | 4 |
616 | Soft tissue rheumatism of the upper extremities: diagnosis and management.
Upper extremity tendinitis and bursitis are usually the result of repetitive microtrauma, probably resulting in disruption of fibers.
A focus of inflammation often occurs, producing pain, spasm, and disability.
With a careful history and phys... | 4 |
1,912 | Potential usefulness of combined thromboxane A2 and serotonin receptor blockade for preventing the conversion from chronic to acute coronary artery disease syndromes.
Evidence suggests that unstable angina, non-Q-wave myocardial infarction and Q-wave myocardial infarcts represent a continuum, such that transient reduc... | 13 |
815 | Should safety concerns with available ulcer treatment influence drug selection?
With the identification of the parietal cell receptors for gastric acid secretion coupled with the introduction of cimetidine in 1977, treatment of acid-peptic diseases was transformed from empiric therapy to an approach based on a clearer... | 5 |
771 | Phase I clinical and pharmacologic study of intraperitoneal cisplatin and fluorouracil in patients with advanced intraabdominal cancer.
Fluorouracil (5-FU) and cisplatin display marked therapeutic synergy in preclinical models and are effective in the treatment of a number of solid tumors when combined and administere... | 5 |
819 | Gallstone dissolution.
Many methods are available for gallstone dissolution, including oral bile salts; cholesterol solvents such as mono-octanoin or methyl tert-butyl either; and calcium or pigment solvents such as EDTA and polysorbate.
Which of these approaches will be appropriate for an individual patient depends ... | 5 |
203 | Trends in basal cell carcinoma, squamous cell carcinoma, and melanoma of the skin from 1973 through 1987.
Major increases have occurred in the incidence of basal cell carcinoma and squamous cell carcinoma of the skin, as well as in cutaneous malignant melanoma during the period 1973 through 1987 in British Columbia.
... | 3 |
295 | Treatment of advanced neuroblastoma with emphasis on intensive induction chemotherapy. A report from the Study Group of Japan.
One hundred nine newly treated patients with advanced neuroblastoma were entered in this study between January 1985 and May 1989.
The eligible patients included infants younger than 12 months... | 3 |
3,269 | Measurements of right ventricular volumes during fluid challenge.
The effects of fluid loading on RV function were studied in 41 acutely ill patients monitored with a modified pulmonary artery catheter equipped for measuring RVef.
Hemodynamic evaluation was performed before and after infusion of 300 ml of 4.5 percent... | 22 |
596 | Healing of non-vascularised diaphyseal bone transplants. An experimental study.
Four different experiments were performed to study the healing of a large, non-vascularised, diaphyseal, bone segment in adult cats.
In the first experiment, a 4 cm segment of tibia with its periosteum was excised and replaced in its bed.... | 4 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.