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497 | Increasing incidence of cecal and sigmoid carcinoma. Data from the Connecticut Tumor Registry.
We have studied both the distribution and incidence of colorectal cancer using The Connecticut Tumor Registry, the oldest tumor registry in the United States.
During the time period 1973 to 1985, left-sided colon cancers ac... | 3 |
3,215 | Prehospital prophylactic lidocaine does not favorably affect outcome in patients with chest pain.
STUDY OBJECTIVES: The purpose of our study was to determine the morbidity and mortality in initially stable patients presenting to paramedics with chest pain; to examine possible beneficial effects of its use, including r... | 22 |
732 | Management of the acute abdomen complicating oral anticoagulation therapy.
Acute abdominal pain in the patient receiving oral anticoagulants poses a difficult diagnostic and therapeutic challenge.
We describe two cases of peritonitis requiring laparotomy in anticoagulated patients, and review 49 similar case reports ... | 5 |
2,045 | New calcium antagonists: relevance of vasoselectivity.
The calcium antagonists are a heterogeneous class of drugs used to treat a number of cardiovascular disorders.
A new generation of calcium antagonists under development have a higher degree of selectivity for vascular smooth muscle and coronary vasculature compar... | 13 |
413 | Constitutional symptoms in patients with germ cell neoplasms.
A patient with a mediastinal germ cell neoplasm evidenced fever, weight loss, pruritus, and painful adenopathy on ingestion of alcohol.
Retrospective review revealed that 9 percent of 104 patients with advanced germ cell neoplasm evidence constitutional sy... | 3 |
1,748 | Does blood rheology revert to normal after myocardial infarction?
After myocardial infarction there is an acute deterioration of the flow properties of blood.
The present study was designed to test whether the abnormality persists.
Blood and plasma viscosity, red cell aggregation and deformability, haematocrit, eryt... | 13 |
2,445 | Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes.
Familial hypercholesterolemia is an inherited disease in humans that is associated with coronary artery disease and is caused by a deficiency of the receptor that mediates ... | 17 |
2,961 | Effects of nonparticipation in trauma center system on emergency department utilization.
The University of Illinois Hospital (UIH) serves an inner-city urban population in one of the highest crime rate districts in Chicago.
On May 20, 1986, the city's Level I Trauma ordinance took effect with the University of Illino... | 20 |
3,051 | Systemic pattern of free radical generation during coronary bypass surgery.
Diffuse impairment of ventricular function after cardiac surgery may be related to the generation during reperfusion of the myocardium of free radicals derived from oxygen.
Fifteen patients undergoing elective coronary bypass surgery were stu... | 22 |
3,187 | Color Doppler diagnosis of mechanical prosthetic mitral regurgitation: usefulness of the flow convergence region proximal to the regurgitant orifice.
In prosthetic or paravalvular prosthetic mitral regurgitation, transthoracic color Doppler flow mapping can sometimes fail to detect the regurgitant jet within the left ... | 22 |
1,401 | Effect of calcium entry blocker nitrendipine on renal function after renal vascular occlusion.
The ability of the Ca entry blocker nitrendipine to improve postischemic renal function was studied in nine groups (n = 70) of rats.
After anesthesia, nitrendipine was administered for 15 min through the femoral vein.
The ... | 11 |
3,283 | Defective dystrophin in Duchenne and Becker dystrophy myotubes in cell culture.
We examined normal and dystrophic human myotubes in cell culture for expression of dystrophin, the protein product of the Duchenne muscular dystrophy locus.
Dystrophin levels in developing myotubes detected by Western blotting increased a... | 22 |
375 | Ampullary carcinoma in patients under 50 years of age with a poor prognosis.
Clinicopathologic features of 145 Japanese patients with ampullary carcinoma were compared among three age groups.
The 145 patients were divided into three groups by the patient's age at the time of operation; there were 24 patients in group... | 3 |
2,881 | Traumatic disruptions of the thoracic aorta: treatment and outcome.
Of 27 patients admitted to our level I trauma center with acute disruption of the thoracic aorta, two patients died of exsanguination before aortic repair.
One patient had massive leakage from the aneurysm after aortography and died during surgery.
... | 20 |
2,963 | Blunt trauma to the heart: the pathophysiology of injury.
Blunt injuries to the heart are common and potentially lethal.
These injuries often go undetected while more obvious problems are treated.
A cardiac injury should be suspected in any patient who sustains severe chest trauma.
The spectrum of cardiac trauma ra... | 20 |
2,776 | Alcohol protects the diaphragm during dietary restriction.
We recently reported that alcoholic rat diaphragm develops greater contractile force than diaphragm of pair-fed control animals.
The present experiment examines whether alcohol or dietary restriction is the more likely cause of this surprising finding.
We co... | 20 |
2,019 | Regeneration of myocardial phosphocreatine in pigs despite continued moderate ischemia.
The effects of 1 hour of mild and moderate reductions in coronary blood flow on myocardial high-energy phosphate levels were evaluated.
Thirty anesthetized pigs were instrumented with left anterior descending arterial and venous c... | 13 |
2,609 | Comparison of aerosolized glycopyrrolate and metaproterenol in acute asthma.
The efficacy of nebulized glycopyrrolate compared with metaproterenol was evaluated in 46 patients with acute asthma.
In a double-blinded, randomized fashion, patients received, as sole therapy, either 2 mg of glycopyrrolate or 15 mg of meta... | 19 |
1,784 | Clinical evaluation of single versus multiple mammary artery bypass.
The superior patency and clinical advantages of internal mammary artery (IMA) grafting are well established.
However, the relative benefits of routine multiple IMA grafting remain uncertain.
To determine whether routine multiple compared with singl... | 13 |
1,392 | In treating impotence, urology and sex therapy are complementary.
Urologists and mental health professionals are neither competitors nor adversaries.
The principles of sex therapy represent a thoughtful and sensitive way to approach patients with almost any clinical problem so that they are more comfortable with the ... | 11 |
2,008 | Transient myocardial ischaemia after acute myocardial infarction.
The prevalence and characteristics of transient myocardial ischaemia were studied in 203 patients with recent acute myocardial infarction by both early (6.4 days) and late (38 days) ambulatory monitoring of the ST segment.
Transient ST segment depressi... | 13 |
909 | Effect of different rates of infusion of propofol for induction of anaesthesia in elderly patients.
The effect of changing the rate of infusion of propofol for induction of anaesthesia was studied in 60 elderly patients.
Propofol was administered at 300, 600 or 1200 ml h-1 until loss of consciousness (as judged by lo... | 7 |
47 | A large outbreak of antibiotic-resistant shigellosis at a mass gathering.
In July 1987, a large outbreak of shigellosis occurred among attendees at a mass gathering in a national forest, the annual Rainbow Family Gathering.
Sanitation in the campsite was poor, allowing widespread transmission of disease, probably by ... | 0 |
1,914 | Effect of beta-adrenergic blocking agents on the circadian occurrence of ischemic cardiovascular events.
Clinical observations suggest that beta-adrenergic blocking agents can modify the circadian occurrence of a variety of ischemic events.
Morning awakening is associated with a rapid increase in blood pressure and p... | 13 |
3,031 | Plasma norepinephrine in chronic schizophrenia.
Several lines of evidence indicate altered noradrenergic function in schizophrenia.
The authors examined resting, standing, and change (standing minus resting) in plasma norepinephrine levels in 14 drug-free patients with chronic schizophrenia or schizoaffective disorde... | 22 |
262 | Compound blue nevus: a variant of blue nevus with an additional junctional dendritic component. A clinical, histopathologic, and immunohistochemical study of six cases.
We studied six cases of heavily pigmented melanocytic lesions with features of blue nevi within the dermis, but with an additional junctional dendriti... | 3 |
1,223 | Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine.
The analgesic efficacy and kinetics of a single oral dose of 75 mg codeine was investigated in 12 extensive metabolizers and 12 poor metabolizers of sparteine in a double-blind, placebo-controlled cross... | 9 |
2,308 | Growth factor and proto-oncogene expression in psoriasis.
The expression of several proto-oncogenes and growth factors was analyzed in normal skin and psoriatic lesions by RNA blot hybridization.
Isolation of intact RNA from frozen biopsy samples required immediate exposure to denaturants during tissue homogenization... | 16 |
858 | Needle aspiration biopsy in salivary gland lesions.
The value of needle aspiration biopsy in the evaluation and management of salivary gland pathology is controversial.
The major reasons for this controversy are the difficulty in cytologic evaluation and the fact that the extent of surgery can be easily defined based... | 6 |
2,453 | Cholesterol-lowering effect of skim milk from immunized cows in hypercholesterolemic patients.
The effect of skim milk from cows immunized against a variety of human intestinal bacteria on serum cholesterol concentrations was examined in 11 patients with primary hypercholesterolemia in a 24-wk, randomized, double-blin... | 17 |
667 | Eosinophilic granuloma of the cervical spine. A case report and review of the literature.
This is a report of a case of eosinophilic granuloma involving the second cervical vertebra in a 33-year-old woman.
There have been 32 case reports in the literature describing eosinophilic granuloma presenting as cervical spine... | 4 |
2,699 | Influence of human immunodeficiency virus infection on reproductive decisions.
This article discusses the role of the practitioner in the pregnancy decision-making process of the HIV-infected woman.
Literature on women's decisions is reviewed, and variables that influence decisions are discussed.
The author conclude... | 19 |
762 | Stasis syndromes following gastric surgery: clinical and motility features of 60 symptomatic patients.
We retrospectively reviewed the records of 60 patients who had been referred for gastrointestinal manometry because of stasis after gastric surgery.
Nausea, vomiting, bloating, abdominal pain, and weight loss were t... | 5 |
2,636 | HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain.
Cells of the mononuclear phagocyte system are the predominant cell producing HIV-1 in most tissues including the central nervous system (CNS), spinal cord, lung and skin; infection is associated with dementia... | 19 |
2,273 | Increased expression of platelet-derived growth factor type B receptors in the skin of patients with systemic sclerosis.
The expression of B-type receptors for platelet-derived growth factor (PDGF) was investigated in skin biopsy samples from patients with systemic sclerosis (SSc), by immunohistochemical staining usin... | 16 |
2,370 | Absence of brown product FFI in nondiabetic and diabetic rat collagen.
Accumulation of brown products in long-lived proteins might be an important factor in determining long-term diabetic complications.
Fluorescent chromophore 2-(2-furoyl)-4-(5)-(2-furanyl)-1H-imidazole (FFI), isolated from hydrolyzed brown products ... | 17 |
3,025 | Cytogenetic analysis of 750 spontaneous abortions with the direct-preparation method of chorionic villi and its implications for studying genetic causes of pregnancy wastage.
Altogether, 750 cases of spontaneous abortion between the fifth and 25th week of gestation were analyzed cytogenetically by the direct-preparati... | 22 |
3,015 | The differentiation of delayed serologic and delayed hemolytic transfusion reactions: incidence, long-term serologic findings, and clinical significance.
Delayed serologic transfusion reactions (DSTRs) and delayed hemolytic transfusion reactions (DHTRs) were studied in a large tertiary-care hospital.
A DSTR was defin... | 22 |
702 | Comparison of omeprazole and cimetidine in reflux oesophagitis: symptomatic, endoscopic, and histological evaluations.
Symptomatic patients with endoscopically verified reflux oesophagitis were randomised to a double blind trial in which they received either omeprazole (20 mg once daily) or cimetidine (400 mg four tim... | 5 |
715 | Albumin absorption and protein secretion by the gallbladder in man and in the pig.
To study albumin absorption by the gallbladder in man, an in vitro model was first established in the pig and compared with in vivo function in the same species.
Water and electrolyte transport and 125I-albumin absorption and protein s... | 5 |
1,437 | One year of rHuEPO therapy prolongs RBC survival and may stabilize RBC membranes despite natural progression of chronic renal failure to uremia and need for dialysis.
rHuEPO was administered to eight patients with chronic renal failure (CRF) and uremia (U) for 1 year.
Creatinine Clearance (GFR) averaged 14.3 (9-25) m... | 11 |
2,813 | The development of medical education on alcohol- and drug-related problems at the University of Toronto.
Medical education on alcohol- and drug-related problems at the University of Toronto covers undergraduate, residency and graduate programs, a result of collaboration since 1959 between the university and the Addict... | 20 |
183 | Comparison of the conventional method of lymph node staging with a comprehensive fat-clearing method for gastric adenocarcinoma.
Discrepant results in long-term survival between United States and Japanese patients with resectable gastric adenocarcinoma may result from more accurate staging in the Japanese series.
The... | 3 |
1,360 | The urethral plug: a new treatment modality for genuine urinary stress incontinence in women.
A new modality, the urethral plug, was used to treat 22 women with genuine urinary stress incontinence.
The plug is made of thermoplastic elastomer (Kraton G), and consists of a meatal plate, a soft stalk and 1 or 2 spheres ... | 11 |
2,152 | Improvement of brain function in hemodialysis patients treated with erythropoietin.
To evaluate the effects of recombinant human erythropoietin (rHuEPO) on brain function, 15 chronic hemodialysis patients were studied by event-related P300, stimulus-related evoked potentials, and trailmaking before (hematocrit 22.7%) ... | 14 |
1,251 | Vision screening in a primary care setting. A missed opportunity?
To determine the effectiveness of vision screening in a primary care setting, we administered a questionnaire and a vision test to 458 patients from a general medical clinic.
Subjects were referred for complete ophthalmologic evaluation if they failed ... | 10 |
1,809 | Abnormal hemodynamic response to Valsalva maneuver in patients with atrial septal defect evaluated by Doppler echocardiography.
Hemodynamic responses to the Valsalva maneuver were studied in eight healthy subjects (group 1) and eight patients with ASD (group 2) using Doppler echocardiography.
The acute changes of aor... | 13 |
3,276 | Muscle maximal O2 uptake at constant O2 delivery with and without CO in the blood.
In the present study we investigated the effects of carboxyhemoglobinemia (HbCO) on muscle maximal O2 uptake (VO2max) during hypoxia.
O2 uptake (VO2) was measured in isolated in situ canine gastrocnemius (n = 12) working maximally (iso... | 22 |
498 | Bronchogenic carcinoma in situ on the carina eradicated by endobronchial biopsy.
Squamous cell carcinoma in situ of the bronchus is a rare disorder in an isolated clinical setting.
We present a case of carcinoma in situ located on the carina with excisional biopsy via a fiberoptic bronchoscope and no recurrence after... | 3 |
2,430 | Increased overnight growth hormone concentrations in diabetic compared with normal adolescents.
To determine the extent to which spontaneous plasma GH concentrations are abnormal in adolescents with insulin-dependent diabetes mellitus we performed 12-h overnight plasma GH profiles in 21 diabetic adolescents (11 males ... | 17 |
1,816 | Calcitropic hormones, platelet calcium, and blood pressure in essential hypertension.
Plasma ionized calcium, platelet cytosolic calcium (using the fura-2 method in gel-filtered platelets), parathyroid hormone (both the intact hormone and a midmolecule portion), calcitriol, and calcidiol were measured in 19 untreated ... | 13 |
2,916 | Knee function after complex femoral fractures treated with interlocking nails.
Twenty-three complex femoral fractures were treated with interlocking nails.
After fracture healing, knee function was analyzed, including alignment, quadriceps and hamstring strength, thigh atrophy, and range of motion (ROM).
Similar to ... | 20 |
3,335 | Maintenance of circulation during ventricular fibrillation with the simultaneous use of two "counterpulsation" devices.
Two valveless, single orifice counterpulsation devices, with pumping stroke volumes of 65 ml each, were implanted on the ascending aorta and pulmonary artery of seven open chest anesthetized dogs.
A... | 22 |
3,081 | Massive allografts in salvage revisions of failed total knee arthroplasties.
Ten patients with failed total knee arthroplasties and severe bone loss were treated with massive whole distal femur and proximal tibial allografts in combination with prosthetic implants.
Fourteen allografts were inserted either as invagina... | 22 |
1,146 | Symptomatic carotid endarterectomy trials.
The possible benefit of carotid endarterectomy in stroke prevention is being evaluated in three major clinical trials.
To date, the European Carotid Surgery Trial has randomized 2,200 patients, 30% of whom have a carotid stenosis of greater than 70% appropriate to their symp... | 9 |
745 | Pancreatitis.
Pancreatitis is a common but rather poorly understood entity most often associated with alcohol abuse or biliary tract disease.
Despite the availability of a variety of diagnostic tests and imaging techniques, the diagnosis of pancreatitis continues to be primarily a clinical one.
Of major concern to t... | 5 |
1,715 | Subaortic obstruction: intraoperative echocardiography as an adjunct to operation.
Fourteen patients undergoing operation for subaortic obstruction (membranous obstruction in 11 patients, tunnel obstruction in 2 patients, obstruction due to reduplicated mitral valve tissue in 1 patient) were evaluated by intraoperativ... | 13 |
324 | Cutaneous melanoma and bilateral retinoblastoma.
We report the case of an otherwise healthy 37-year-old man who had had bilateral enucleation during early childhood for bilateral retinoblastomas, in addition to two cutaneous melanomas (the first appearing at age 27 years).
He also had dysplastic melanocytic nevi and ... | 3 |
2,125 | Are blood pressure levels increasing in Denmark?
The Copenhagen City Heart Study is a prospective cardiovascular population study designed to evaluate the incidence of and risk factors for cardiovascular disease.
A random population sample comprising approximately 20,000 individuals was invited to participate.
Blood... | 13 |
2,463 | Behavioral covariates of waist-to-hip ratio in Rancho Bernardo.
We examined lifestyle and dietary habits in 685 men and 943 women (mean age 67 years) who completed an interview, examination, and food frequency questionnaire in 1984-87.
Waist-to-hip ratio increased with age and body mass index in both men and women.
... | 17 |
657 | Determinants of vertebral mineral density in patients receiving long-term glucocorticoid therapy.
This study addresses the impact of clinical and biochemical factors on the bone density of patients receiving glucocorticoid therapy.
Vertebral mineral density was measured by quantitative computed tomography in 35 patie... | 4 |
2,686 | Effect of inhaled methacholine on inspiratory flow.
One hundred consecutive outpatients with symptoms suggestive of asthma who came to the Pulmonary Function Laboratory for a methacholine challenge test were studied.
In addition to the forced expiratory maneuvers, forced inspiratory maneuvers were performed before an... | 19 |
2,163 | Bioavailability of iron in hemodialysis patients treated with erythropoietin: evidence for the inhibitory role of aluminum.
The dose of recombinant human erythropoietin (r-HuEPO) required to correct the anemia of end-stage renal disease (ESRD) varies among patients.
The response to r-HuEPO is impaired if absolute or ... | 14 |
81 | Postneonatal infectious disease mortality: the French situation.
Mortality caused by infectious and parasitic diseases represents a limited part of all postneonatal deaths in France, which have been stable for the past decade.
This component is worthy of careful analysis because it is at least partially preventable.
... | 0 |
1,228 | Transcranial electrical stimulation with high frequency intermittent current (Limoge's) potentiates opiate-induced analgesia: blind studies.
Transcutaneous cranial electrical stimulation (TCES) with high frequency (166 kHz) intermittent current (100 Hz: Limoge current) has been used for several years in cardiac, thora... | 9 |
860 | Long-term fate of the vascularized iliac crest bone graft for mandibular reconstruction.
Vascularized bone grafts, such as the iliac crest, have become a major tool for mandibular reconstruction.
Due to the growing trend toward immediate bone replacement followed by implant osseointegration and dental rehabilitation,... | 6 |
2,464 | The delta (delta) gap: an approach to mixed acid-base disorders
The anion gap (AG) is a helpful, yet underused, clinical tool.
Not only does the presence of a high AG suggest a certain differential, but knowledge of the relationship between the rise in AG (delta AG) and the fall in bicarbonate (delta HCO3) is import... | 17 |
2,051 | Physiology and pharmacology of cardiovascular catecholamine receptors: implications for treatment of chronic heart failure.
In the sympathetic nervous system the physiologic effects of the endogenous catecholamines noradrenaline (NA) and adrenaline (A) are mediated by alpha- and beta-adrenoreceptors (ARs).
Both AR-ty... | 13 |
3,312 | Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity.
The receptors for erythropoietin and other cytokines constitute a new superfamily.
They have no tyrosine-kinase or other enzyme motif and their signal-transducing mechanism is unclear... | 22 |
2,528 | Defective fasciculata zone function as the mechanism of glucocorticoid-remediable aldosteronism.
Glucocorticoid-remediable aldosteronism is characterized by unusual sensitivity of aldosterone secretion to ACTH.
Suppressibility by glucocorticoid and continued stimulability by exogenous ACTH has provided the basis for ... | 18 |
1,303 | A portable digital data recorder for long-term monitoring of scrotal temperatures
The application of a new, miniaturized portable digital data recorder "Thermoport" (Institute for Reproductive Medicine, Munster, West Germany) for continuous determination of scrotal temperatures revealed great variations of scrotal te... | 11 |
1,074 | Cerebral effects of sevoflurane in the dog: comparison with isoflurane and enflurane.
The cerebral effects of sevoflurane were compared in dogs with those of enflurane and isoflurane.
Initially, the minimum alveolar concentrations (MAC) of sevoflurane and enflurane were determined and the electroencephalographic (EEG... | 9 |
3,226 | Bilateral phrenic nerve palsy associated with open-heart surgery.
The incidence of phrenic nerve palsy after open-heart surgery has been estimated at 10%, but it is usually unilateral and does not cause symptoms.
Bilateral phrenic nerve injury after coronary artery bypass surgery is a rare complication.
This case re... | 22 |
1,423 | Sterile versus non-sterile dialysis fluid in chronic hemodialysis treatment.
As the quality of water in the dialysis fluid varies considerably, and in view of the fact that endotoxin or active derivatives can cause acute side effects in patients, the dialysis fluid must be sterile.
Therefore, we introduced ultrafiltr... | 11 |
754 | Endoscopic retrograde cannulation of the gallbladder: direct dissolution of gallstones.
Percutaneous transhepatic catheterization of the gallbladder for dissolution of cholesterol stones by instillation of methyl tert-butyl ether (MTBE) is an invasive therapeutic procedure.
The only non-invasive alternative available... | 5 |
1,926 | Subnormal parasympathetic activity after cardiac transplantation.
Heart period variability (standard deviation of 120 consecutive RR or PP intervals) was used to assess baseline parasympathetic activity in 18 patients with congestive heart failure before and after orthotopic cardiac transplantation, and was compared t... | 13 |
3,273 | Stress adaptation and low-frequency impedance of rat lungs.
At transpulmonary pressures (Ptp) of 7-12 cmH2O, pressure-volume hysteresis of isolated cat lungs has been found to be 20-50% larger than predicted from their amount of stress adaptation (J.
Hildebrandt, J.
Appl.
Physiol.
28: 365-372, 1970).
This behavio... | 22 |
2,063 | Preanaesthetic medication with clonidine.
The purpose of this study was to evaluate oral clonidine in a dose of 0.3 mg as a routine premedicant.
Sixty-nine normotensive female patients were studied in a randomized double-blind investigation in which clonidine was compared with an inert treatment.
Clonidine produced ... | 13 |
2,345 | Nature, nurture, nutrition: interdisciplinary programs to address the prevention of malnutrition and dehydration.
Malnutrition and dehydration are common problems in nursing home patients.
One explanation for this may be the large number of patients requiring feeding assistance.
The Dysphagia Team at the Department ... | 17 |
2,599 | Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens
A randomized trial of 12.0 Gy versus 15.75 Gy of total body irradiation (TBI) was performed in patients with acute myeloid leukemia undergoing allogeneic marrow transplantation ... | 19 |
1,706 | Hemodynamic effects of nebivolol at rest and on exertion in patients with heart failure.
Nebivolol is a novel B-1-adrenoceptor-blocking drug with an unusual hemodynamic profile unlike classical B-blockers.
In dogs and in healthy volunteers it decreases blood pressure and heart rate but improves left ventricular funct... | 13 |
1,362 | The management of posterior urethral valves by initial vesicostomy and delayed valve ablation.
We managed 32 neonates and infants with temporary vesicostomy and delayed valve ablation.
The criterion on which successful management was gauged was estimated creatinine clearance.
Renal failure or death occurred in 30% o... | 11 |
2,002 | Biplane transesophageal echocardiography: technique, image orientation, and preliminary experience in 131 patients.
Transesophageal echocardiography with use of a uniplane phased-array transducer with a transverse or horizontal scanning plane has become a well-established tool for evaluating cardiovascular diseases.
... | 13 |
323 | Buschke-Loewenstein tumor: verrucous carcinoma of the penis.
The Buschke-Loewenstein tumor is an anogenital tumor of characteristic clinical and histologic pattern best considered as a low-grade, well-differentiated squamous cell carcinoma.
This remarkable neoplasm and its features are reviewed in detail, stressing s... | 3 |
2,422 | Hepatic and extrahepatic responses to insulin in NIDDM and nondiabetic humans. Assessment in absence of artifact introduced by tritiated nonglucose contaminants.
It is well established that patients with non-insulin-dependent diabetes mellitus (NIDDM) are resistant to insulin.
However, the contribution of hepatic and... | 17 |
419 | Immunophenotypic aberrancy in adult acute lymphoblastic leukemia.
Some recent reports indicate a high frequency of immunophenotypic aberrancy in acute lymphoblastic leukemia (ALL).
To investigate this issue with regard to adult ALL, the authors reviewed the immunophenotyping data from 39 cases analyzed in their clini... | 3 |
3,182 | Molecular biology of circulatory shock. Part III. Human hepatoblastoma (HepG2) cells demonstrate two patterns of shock-induced gene expression that are independent, exclusive, and prioritized.
During shock and resuscitation, parenchymal cells of solid organs are exposed to a rapidly changing microenvironment, which ma... | 22 |
1,128 | Anti-GM1 IgM antibodies in motor neuron disease and neuropathy.
We found anti-GM1 IgM antibodies in 23% of 56 patients with motor neuron disease (MND), in 19% of 69 patients with neuropathy, and in 7% of 107 controls with other neurologic and nonneurologic diseases.
Most of these patients had anti-GM1 IgM antibody ti... | 9 |
428 | Immediate versus delayed shoulder exercises after axillary lymph node dissection.
A total of 144 evaluable patients with breast cancer were enrolled in a multicenter, randomized, prospective study to establish the role of delayed shoulder exercises on wound drainage and shoulder function after axillary lymph node diss... | 3 |
1,911 | Mental stress as an acute trigger of ischemic left ventricular dysfunction and blood pressure elevation in coronary artery disease.
Acute mental stress may be a frequent trigger of transient myocardial ischemia, myocardial infarction and sudden cardiac death.
In an experimental setting, the effect of mental stress on... | 13 |
223 | Trends in primary breast cancer management. Where are we going?
The treatment of cancer during any period has been based not on the whim of a clinician but on the therapeutic consequences of the dominant biologic model of the disease.
Until the 1960s, the dominant model of breast cancer was of a disease that spread c... | 3 |
184 | Neuropeptide Y and neuron-specific enolase levels in benign and malignant pheochromocytomas.
Neuron-specific enolase (NSE) is the isoform of enolase, a glycolytic enzyme found in the neuroendocrine system.
Neuropeptide Y (NPY) is a peptide recently discovered in the peripheral and central nervous systems.
Serum NSE ... | 3 |
2,039 | Development and prospective application of quantitative 2-day stress-rest Tc-99m methoxy isobutyl isonitrile SPECT for the diagnosis of coronary artery disease.
The clinical diagnostic accuracy of 2-day stress/rest quantitative Technetium-99m (Tc-99m) methoxy-isobutyl-isonitrile (Tc-sestamibi) single photon emission c... | 13 |
2,967 | Antibiotics and the postburn hypermetabolic response.
Severe burn injury has been documented to significantly increase resting metabolic energy expenditure.
This increase in metabolic rate appears to be possibly correlated with the degree of burn wound colonization and infection with bacteria.
Prevention of such col... | 20 |
3,203 | Metaplastic change in mesenchymal stem cells induced by activated ras oncogene.
3T3 T murine mesenchymal stem cells have the potential to differentiate into a variety of different cell types even though they show a predilection to undergo adipocyte differentiation in vitro.
The possibility that the activated c-Ha-ras... | 22 |
2,036 | Warm induction blood cardioplegia in the infant. A technique to avoid rapid cooling myocardial contracture.
The use of profound hypothermia and total circulatory arrest for repair of heart defects in neonates usually involves a period of systemic and myocardial bypass cooling.
Rapid cooling of muscle (skeletal, smoot... | 13 |
1,792 | Bradyarrhythmia after heart transplantation. Incidence, time course, and outcome.
From June 1980 to April 1989, 72 of 401 (18%) adult recipients of orthotopic heart transplantation developed prolonged (greater than 24 hours) bradyarrhythmias (less than 60 beats/min) within 5 days after transplantation.
Junctional bra... | 13 |
1,133 | Confusion.
The term confusion describes a plethora of possible cognitive deficits and behavioral manifestations.
A subjective assessment of confusion must be followed by an objective systematic evaluation to develop the cognitive-behavior profile.
Because of age-associated physiologic and pathologic changes, elderly... | 9 |
1,336 | Sedoanalgesia in urology: a safe, cost-effective alternative to general anaesthesia. A review of 1020 cases.
Sedoanalgesia is a technique developed to provide safe and satisfactory operating conditions for a wide range of patients independent of age and overall level of fitness (although its use in children remains to... | 11 |
922 | Real and pseudo late asthmatic reactions after submaximal exercise challenge in patients with bronchial asthma. A new definition for late asthmatic responses after exercise challenge.
The late asthmatic reaction after exercise challenge remains a controversial issue.
In this study, 21 patients recorded peak expirator... | 7 |
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