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2,608 | Effect of facial cooling on mucosal blood flow in the mouth in humans.
1.
To determine the effects of facial cooling on intraoral thermal events, we placed a thermal conductivity sensor on the buccal surface of the left cheek in six normal and six asthmatic subjects.
Room temperature and cold stimuli were then appli... | 19 |
264 | Left superior vena cava: a pitfall in computed tomographic diagnosis with surgical implications.
We report 2 cases in which computed tomography of the mediastinum demonstrated an abnormality originally misinterpreted as lymphadenopathy but subsequently shown to represent a left superior vena cava.
Misinterpretation m... | 3 |
1,866 | Intraoperative peripheral Nd:YAG laser-assisted thermal balloon angioplasty: short-term and intermediate-term follow-up.
Laser-assisted thermal balloon angioplasty was performed in 48 arteries (iliac, superficial femoral, and popliteal).
Indications for surgery were limb salvage (25%), rest pain (38%), and claudicati... | 13 |
682 | Investigation of mode of action of biofeedback in treatment of fecal incontinence.
A study was carried out in 25 incontinent patients to evaluate some of the factors thought to be responsible for the success of retraining for fecal incontinence.
Subjects were initially allocated to one of two groups; one group was tr... | 5 |
2,367 | Absence of angiogenesis-inhibitory activity in aqueous humor of diabetic rabbits.
We studied inhibitory activity of angiogenesis in the eye to explore the formation of new blood vessels in diabetic microvascular diseases.
When we examined the effects of extracts from various ocular tissues of nondiabetic rabbits on t... | 17 |
17 | hemofiltration reverses left ventricular dysfunction during sepsis in dogs.
Depressed left ventricular (LV) contractility in sepsis has been ascribed to the presence of circulating cardiodepressant substance (filterable cardiodepressant factor in sepsis [FCS]); however, this finding is controversial.
The authors hypo... | 0 |
724 | Early results of combined electrohydraulic shock-wave lithotripsy and oral litholytic therapy of gallbladder stones at the University of Iowa.
One hundred thirty-three patients were entered into a randomized, double-blind, placebo-controlled trial of extracorporeal shock-wave lithotripsy for symptomatic gallstones ver... | 5 |
1,673 | Clinical and electrophysiologic characteristics of patients with antidromic circus movement tachycardia in the Wolff-Parkinson-White syndrome.
Antidromic circus movement tachycardia was documented in 36 of 345 consecutive patients with Wolff-Parkinson-White syndrome undergoing detailed electrophysiologic evaluation.
... | 13 |
3,091 | Progressive functional deterioration of bioprostheses assessed by Doppler ultrasonography.
Doppler echocardiography was used to study the function of bioprosthetic heart valves by noninvasive means in 32 patients aged 29 to 72 years at various postoperative intervals.
There were 24 Ionescu-Shiley, four Hancock, and f... | 22 |
2,677 | Silk-induced asthma in children: a report of 64 cases.
A total of 64 children less than 15 years of age with asthma caused by silk were studied.
The diagnosis was based on a history of wheezing, positive skin tests to silk, positive conjunctival or nasal provocation tests, or serum IgE-Sw (silk waste).
The average a... | 19 |
385 | Ultrastructural evidence for differentiation in a human glioblastoma cell line treated with inhibitors of eicosanoid metabolism.
Human glioblastoma cells incubated in the presence of inhibitors of eicosanoid biosynthesis show decreased cellular proliferation without cytotoxicity.
We studied the ultrastructural morpho... | 3 |
2,427 | Glucose and gluconeogenic substrate exchange by the forearm skeletal muscle in hyperglycemic and insulin-treated type II diabetic patients.
To determine the contribution of skeletal muscle to fasting hyperglycemia in noninsulin dependent type II diabetes (NIDDM), the forearm balance of glucose, lactate, and alanine wa... | 17 |
583 | The importance of calcium regulation in toxic cell injury. Studies utilizing the technology of digital imaging fluorescence microscopy.
The regulation of ions within the cell is of critical importance in both acute and chronic toxicology.
Recently, new methods have been developed for measuring such changes in living ... | 3 |
2,779 | Ethanol-inducible cytochrome P-450: assessment of substrates' specific chemical probes in rat liver microsomes.
The capacity of liver microsomes to oxidize various substrates known to be specific of alcohol-inducible cytochrome P-450 was studied in rats treated with different xenobiotics such as 3-methylcholanthrene, ... | 20 |
303 | Familial occurrence of gastric cancer in the 2-year experience of a population-based registry.
The authors studied the familial occurrence of tumors in 154 individuals with gastric cancer by reviewing the clinical data and the genealogical tree of all patients registered in 1986 through 1987 in the Local Health Care D... | 3 |
3,300 | Effect of motion artefact on pulse oximeters: evaluation of four instruments and finger probes.
The ability of the Ohmeda 3700, Nellcor N200, Datex Satlite Plus and Simed S100 pulse oximeters to detect induced hypoxaemia in the presence of motion artefact was assessed, under conditions of controlled vibration using an... | 22 |
636 | Estrogen therapy during menopause and the treatment of osteoporosis.
Estrogen remains the single most effective agent in the treatment of menopausal symptoms and prevention of bone loss.
This article focuses on the use of estrogen therapy during menopause and the pharmacotherapy of osteoporosis.
Risks and benefits o... | 4 |
2,031 | Vascular flow capacity of hindlimb skeletal muscles in spontaneously hypertensive rats.
Total and regional skeletal muscle flows (radiolabeled microspheres) were determined in isolated maximally vasodilated hindquarters of spontaneously hypertensive rats (SHR) and age-matched (11-12 mo) normotensive Wistar-Kyoto rats ... | 13 |
1,996 | Circumferential quantitative analysis of planar 201T1 myocardial scintigraphy in the diagnosis of coronary artery disease.
Methodology for the computer analysis of 201T1 myocardial perfusion images has been developed by several laboratories.
Substantial evidence of the advantage of this approach over visual inspectio... | 13 |
3,345 | Assessment of the biliary tract after liver transplantation: T tube cholangiography or IODIDA scanning.
Biliary tract obstruction or anastomotic leakage are common problems following liver transplantation.
In a sequential study, 31 patients with a liver transplant were investigated by 99mTc-IODIDA (IODIDA) scanning a... | 22 |
3,103 | Desmopressin and antifibrinolytics.
Desmopressin appears to be a safe and effective hemostatic agent for use during surgery in patients with mild to moderate hemophilia or von Willebrand disease.
Uremic patients also benefit from substitution of desmopressin for cryoprecipitate to control bleeding.
The highly variab... | 22 |
645 | Mother-daughter pairs: spinal and femoral bone densities and dietary intakes.
Bone mineral density (BMD) of the lumbar spine (L1-L4) and femur (femoral neck, Ward's triangle, and trochanter) was measured in 37 healthy, white mother-daughter pairs by dual-photon absorptiometry.
Mothers and daughters were aged 52 +/- 7... | 4 |
2,235 | Development of a new transvenous patent ductus arteriosus occlusion technique using a shape memory polymer.
A novel percutaneous patent ductus arteriosus (PDA) occlusion technique, without the potential problems associated with conventional techniques, has been long awaited.
The development of a novel transvenous PDA... | 15 |
3,043 | Urinary tract re-functionalization after long-term diversion. A 20-year experience with 177 patients.
From 1969 to 1990, previously diverted urinary tracts were 'undiverted' in 177 patients whose ages ranged from 1 to 31 years.
Fifty-six of the patients (32%) had been diverted for 10 years or longer.
There were 67 f... | 22 |
2,546 | Oral calcium load test: diagnostic and physiologic implications in hyperparathyroidism.
An oral calcium load test (CLT) (1 gm Ca/50 kg) was administered to 11 control subjects and 35 patients with overt hyperparathyroidism to assess its efficacy in diagnosis of hyperparathyroidism.
All participants were placed on a l... | 18 |
2,573 | Determinants of in vivo histamine release in cutaneous allergic reactions in humans.
To determine host factors influencing the magnitude of mediator release during ongoing cutaneous allergic reactions in humans, we compared, in 22 subjects, the first-hour, second- to fifth-hour, and total (0 to 5 hours) skin chamber h... | 19 |
1,373 | A dose titration study evaluating terazosin, a selective, once-a-day alpha 1-blocker for the treatment of symptomatic benign prostatic hyperplasia.
The efficacy and safety of terazosin, a selective long-acting alpha-1-adrenergic blocker, were evaluated in 45 normotensive patients with symptomatic benign prostatic hype... | 11 |
2,173 | Alterations in pulmonary mechanics after transfusion in anemic preterm infants.
Pulmonary mechanics were studied in ten anemic preterm infants using an esophageal balloon and mask, before and after transfusion with 10 ml/kg of packed RBC.
Their mean birth weight was 1212 +/- 323 g and gestational age was 29.27 +/- 2.... | 14 |
2,754 | Tricyclic antidepressant overdose: conservative management in a community hospital with cost-saving implications.
Reports of late-onset cardiovascular complications following tricyclic antidepressant (TCA) overdose have led to a very conservative approach to these patients.
Many patients have been hospitalized for co... | 20 |
2,910 | Flumazenil: a benzodiazepine antagonist.
Although benzodiazepines have been proven safe and effective for the induction and maintenance of sedation, some instances require the reversal of these events prior to the natural process of metabolism and elimination.
Flumazenil, a 1,4-imidazobenzodiazepine, is an antagonist... | 20 |
1,793 | Factors affecting survival in total artificial heart recipients before transplantation.
To identify factors affecting the successful bridge to transplantation, experience with 32 recipients of the Jarvik-7 artificial heart was reviewed.
Between patients with and without a successful bridge, there were no significant ... | 13 |
1,716 | Use of the variable-length intraluminal sutureless graft.
From August 1987 to May 1988 we treated 4 patients with acute ascending aortic dissections with a variable-length intraluminal aortic prosthesis.
This operation uses profound hypothermic circulatory arrest and represents a refinement of existing techniques.
T... | 13 |
1,340 | Familial testicular cancer in five members of a cancer-prone kindred.
Of a family of 13 siblings, four brothers have developed testicular neoplasms, one embryonal cell carcinoma and three testicular seminomas.
A first cousin once removed on their mother's side of the family (fourth-degree relative) has developed an e... | 11 |
280 | Surgical treatment of brain metastases in malignant melanoma.
The authors report the results of a retrospective review of 13 patients who underwent 19 craniotomies for resection of metastatic malignant melanoma at the University of Colorado (Denver, CO) between 1983 and 1989.
There was preoperative evidence of extrac... | 3 |
1,041 | Dementia, depression, or grief? The differential diagnosis.
Depression, grief, and dementia are conditions frequently encountered among the community-living elderly.
This review offers a primary care perspective of the distinguishing features for each and discusses the special issues of managing the elderly.
Major d... | 9 |
1,610 | Mitral stenosis: evaluation with MR imaging after percutaneous balloon valvuloplasty.
To evaluate the pathoanatomic findings of mitral valve stenosis and changes after percutaneous balloon valvuloplasty (PBV), magnetic resonance (MR) imaging was performed in 23 patients.
The patients were imaged with a 2.0-T system w... | 13 |
1,756 | Conservative management of asymptomatic popliteal aneurysm.
Historical review shows that the treatment of popliteal aneurysm has developed by trial and error and there is disagreement about the proper management of the symptomless patient.
In 1981 a policy of conservative management for asymptomatic popliteal aneurys... | 13 |
2,234 | Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum.
Respiratory distress and progressive lung destruction in cystic fibrosis can be attributed to bacterial persistence and the accumulation of viscous purulent secretions in the airways.
More than 30 yr ago it was suggested that the large amounts... | 15 |
1,221 | Quantitative assessment of extradural bupivacaine analgesia.
Bupivacaine (0.5%) 20 ml was administered extradurally to six healthy volunteers.
It was found that simultaneous application of 10 needles to the skin could evoke pain when analgesia was obtained to one needle stimulation.
In addition, a laser beam was use... | 9 |
2,555 | Angiotropic (intravascular) large cell lymphoma. A clinicopathologic study of seven cases with unique clinical presentations.
The authors recently reported the antigenic phenotypes of three cases of so-called "malignant angioendotheliomatosis" and suggested that angiotropic large cell lymphoma (ALCL) is a more appropr... | 19 |
475 | Magnetic resonance imaging of vertebral osteoblastoma: a report of two cases.
Two patients with vertebral osteoblastoma evaluated with computed tomography and magnetic resonance imaging are presented.
A literature review revealed that cases of osteoblastoma originating within the vertebral body are exceedingly rare.
| 3 |
1,242 | Primary progressive aphasia. Longitudinal course, neuropsychological profile, and language features.
Four patients with the clinical syndrome of primary progressive aphasia and a nonfluent aphasia profile were followed up over a period of 3 to 5 years.
Extensive neuropsychological data for three patients revealed a p... | 9 |
2,816 | Treatment of juxtaarticular nonunion fractures at the knee with long-stem total knee arthroplasty.
A retrospective study of ten patients with juxtaarticular nonunions at the knee treated with long stem total knee arthroplasty was performed.
The average age of the patients was 76 years old, with an average follow-up o... | 20 |
3,088 | Effect of amiodarone on erythrocyte shape and membrane properties.
1.
Amiodarone is a potent anti-arrhythmic drug with lipophilic properties.
The intercalation of such a drug into the membrane of erythrocytes may alter their shape and have an impact on the flow properties of blood.
We therefore studied the influenc... | 22 |
1,387 | Prognostic implications of disappearance rate of biologic markers following radical prostatectomy.
Six patients with localized prostatic carcinoma undergoing radical prostatectomy were studied by serial sample collection from the time of surgical removal of the prostate up to one week in the postoperative period.
Of ... | 11 |
1,000 | Aqueous beclomethasone diproprionate nasal spray: regular versus "as required" use in the treatment of seasonal allergic rhinitis.
OBJECTIVE: to determine the effect of alternative regimens of nasal steroid administration on symptoms and quality of life.
DESIGN: randomized, double-blind, parallel-group comparison.
S... | 8 |
64 | Infectious diseases as a Canadian subspecialty, with projections to the year 2000.
Infectious diseases is a relatively new subspecialty in Canada.
During the past decade, however, important advances have been made.
These include the formation of the Canadian Infectious Diseases Society and the development of the fir... | 0 |
2,272 | Alteration of the cellular fatty acid profile and the production of eicosanoids in human monocytes by gamma-linolenic acid.
We administered borage seed oil (9 capsules/day) for 12 weeks to 7 normal controls and to 7 patients with active rheumatoid arthritis.
The therapy provided 1.1 gm/day of gamma-linolenic acid (GL... | 16 |
3,264 | Intrathoracic current flow during transthoracic defibrillation in dogs. Transcardiac current fraction.
To achieve transcardiac threshold current during transthoracic defibrillation, a considerably larger current must be delivered to the thorax to compensate for the shunting effect of the lungs, the thoracic cage, and ... | 22 |
431 | The single-breath nitrogen test, mortality, and cancer.
The relationship between indices of the single-breath nitrogen test and mortality, overall cancer incidence, and respiratory cancer incidence was examined in a cohort of 876 men, 46 to 69 yr of age, examined in 1974 and followed until June 1985.
Closing volume, ... | 3 |
208 | Direct interaction of a ligand for the erbB2 oncogene product with the EGF receptor and p185erbB2.
The erbB2 oncogene encodes a 185-kilodalton transmembrane protein whose sequence is similar to the epidermal growth factor receptor (EGFR).
A 30-kilodalton factor (gp30) secreted from MDA-MB-231 human breast cancer cell... | 3 |
2,237 | Changes in circulating alphafetoprotein following administration of mifepristone in first trimester pregnancy.
The occurrence of fetomaternal haemorrhage was investigated in 30 women by measuring maternal serum alphafetoprotein (AFP) levels before and after the administration of mifepristone (RU 486) for termination o... | 15 |
1,564 | A rapid, effective technique for retrograde crossing of valvular aortic stenosis using standard coronary catheters
Retrograde crossing of valvular aortic stenosis can be challenging even to experienced angiographers.
In 446 of 447 consecutive patients with aortic stenosis catheterized during the past 3 years, a tech... | 13 |
2,061 | Effect of halothane and isoflurane on postischemic "stunned" myocardium in the dog.
Short periods of coronary artery occlusion are known to produce prolonged periods of ventricular dysfunction.
The effects of halothane or isoflurane on contractility and metabolism in postischemic "stunned" myocardium were studied in ... | 13 |
585 | Function after amputation, arthrodesis, or arthroplasty for tumors about the knee.
We studied the function of twenty-two patients who had had a malignant skeletal tumor adjacent to the knee.
An above-the-knee amputation was done in seven; a resection arthrodesis, in nine; and a replacement arthroplasty, in six.
The ... | 3 |
299 | Increased expression of the multidrug-resistance gene in undifferentiated sarcoma.
We analyzed multidrug-resistance gene (mdr1 gene) expression in a patient with undifferentiated sarcoma of the liver using the cloned cDNA for the mdr1 gene.
Tissue samples were available at the time of initial diagnosis and of two int... | 3 |
757 | Witzel pneumatic dilation for achalasia: safety and long-term efficacy
Forceful dilation of the lower esophageal sphincter is considered primary therapy for achalasia.
The Witzel pneumatic balloon dilator, unlike fluoroscopically placed dilators, is placed over a standard gastroscope allowing positioning and dilatio... | 5 |
2,513 | Management of primary hypothyroidism.
Primary hypothyroidism is a common condition requiring lifelong treatment and monitoring.
The type and amount of thyroid hormone replacement, selection of laboratory tests, and timing of office visits are all important for optimizing patient well-being and reducing the costs of m... | 18 |
1,191 | Osseointegration of titanium implants in total hip arthroplasty.
Osseointegration is defined as direct contact on the light microscopic level between living bone tissue and the implant.
Using titanium screw dental implants in the jaw, a lasting interface under loaded conditions extending over a 20-year follow-up peri... | 9 |
336 | Prognostic value of c-myc proto-oncogene overexpression in early invasive carcinoma of the cervix.
The prognostic effect of c-myc oncogene overexpression was assessed in a multivariate analysis of 93 patients with invasive carcinoma of the cervix, stage Ib, IIa, and IIb proximal.
The treatment was based on the associ... | 3 |
1,575 | Severe aortic regurgitation as a late complication of temporal arteritis.
Two patients with a remote history of pathologically documented giant cell arteritis developed severe regurgitation.
The first patient developed severe aortic regurgitation five years after the pathologic documentation of giant cell arteritis o... | 13 |
2,153 | Molecular defect of the band 3 protein in southeast Asian ovalocytosis
BACKGROUND.
Southeast Asian ovalocytosis is a form of hereditary elliptocytosis in which the red cells are rigid and resistant to malaria invasion.
The underlying molecular defect is unknown.
METHODS AND RESULTS.
We studied the red cells of 54... | 14 |
101 | Thoracic empyema: causes, diagnosis, and treatment.
Thoracic empyema is a disease that has been recognized for centuries.
The principles of management as stated by Hippocrates remain more or less unchanged.
Diagnosis can be masked by the underlying cause, preemptive antibiotic treatment, or the now frequently associ... | 0 |
2,972 | Isolation of Tete serogroup bunyaviruses from Ceratopogonidae collected in Colorado.
Two viruses were isolated from ceratopogonid midges collected in northern Colorado.
Electron microscopy indicated that both isolates were bunyavirus-like.
Indirect fluorescent antibody and serum dilution-plaque reduction neutralizat... | 21 |
392 | Expression of murine renin genes in subcutaneous connective tissue.
A renin promoter-large tumor antigen (T antigen) fusion gene was constructed to provide a reporter function for renin expression in transgenic mice.
These transgenic mice gave rise to tumors in subcutaneous soft tissue, which was attributed to transg... | 3 |
626 | Electrophysiological spectrum of inclusion body myositis.
We present electrodiagnostic data on 30 patients with inclusion body myositis (IBM) in order to better delineate its electrophysiological features.
Comprehensive electromyography (EMG) and nerve conduction studies (NCS) were performed in all cases.
Twelve pat... | 4 |
2,035 | Studies of myocardial protection in the immature heart. II. Evidence for importance of amino acid metabolism in tolerance to ischemia.
This study tests the importance of amino acid transamination in determining the tolerance of immature hearts to ischemic damage.
Amino acid transamination was inhibited metabolically ... | 13 |
2,663 | Profile of bronchospastic disease in Puerto Rican patients in New York City. A possible relationship to alpha 1-antitrypsin variants.
A high prevalence of asthmalike symptoms was noted among patients of Puerto Rican descent attending Beth Israel and North Central Bronx Medical Centers in New York City, as compared wit... | 19 |
3,047 | The efficacy of central venous and pulmonary artery catheters and therapy based upon them in reducing mortality and morbidity.
The purpose of this study was to (1) evaluate the relative cost effectiveness of the central venous pressure and flow-directed pulmonary artery catheters used to maintain normal hemodynamic va... | 22 |
2,190 | Natural and modified history of complete atrioventricular septal defect--a 17 year study.
We reviewed 103 cases of isolated complete atrioventricular septal defect.
These cases represented 4.4% of the cases of congenital heart disease diagnosed in our hospital by catheterisation and angiography during 1971-88.
Most ... | 15 |
2,584 | Bronchoconstriction induced by spirometric maneuvers in patients with bronchial asthma.
We analyzed forced expiration maneuver-induced bronchoconstriction in 14 asthmatic patients and in seven normal subjects by breaking down the forced expiration maneuver of spirometry (the FVC maneuver) into two phases: a slow, deep... | 19 |
1,317 | The case for no initial treatment of localized prostate cancer.
This contribution summarizes the evidence from the natural history and pathology of this disease that, given the high incidence of latent cancer, a policy of radical treatment at diagnosis will represent over-treatment in the majority of cases.
As yet, n... | 11 |
1,404 | Hyaluronic acid (Sperm Select) improves retention of sperm motility and velocity in normospermic and oligospermic specimens.
The effects of Sperm Select (Pharmacia AB, Uppsala, Sweden), a hyaluronic acid medium, on the motility and membrane integrity properties of sperm were studied.
In 15 normospermic specimens afte... | 11 |
3,178 | Cytomegalovirus in a macerated second trimester fetus: persistent viral inclusions on light and electron microscopy.
The macerated stillborn fetus represents at least one third of all perinatal deaths.
Microscopic examination of these specimens is often unrewarding.
We have reported a clinically unsuspected cytomega... | 22 |
1,984 | Carotid endarterectomy: a ten-year analysis of outcome and cost of treatment.
Between 1978 and 1988, 215 patients with an average age of 67 years, underwent 246 carotid endarterectomies.
Two hundred ten (85.4%) patients were symptomatic, and 36 (14.6%) were asymptomatic.
Six patients (2.4%) had a postoperative strok... | 13 |
1,007 | Hearing aids for high-frequency hearing loss.
This cross-over study compares the relative benefits of a standard NHS contracted hearing aid with a high-frequency emphasis commercial aid in subjects with high-frequency hearing loss.
Disability questionnaires and free-field speech-in-noise (FAAF II) tests were used to ... | 8 |
1,292 | Posterior horizontal and vertical tightening to treat combined punctal ectropion with medial canthal tendon laxity.
The classical operations to treat either medial canthal tendon laxity or punctal aversion occurring alone possess drawbacks if they are used to treat these conditions when they occur simultaneously.
A s... | 10 |
2,397 | Use of Doppler flow velocity waveform analysis in detection of initial diabetic microangiopathy.
Doppler flow velocity waveform analysis (FVWFA), recorded from the dorsalis pedis artery (DPA) and the radial artery (RA), was performed on 36 women in attempting to detect an initial diabetic microangiopathy (DM).
The st... | 17 |
1,179 | Cerebral hemodynamics in patients with normal pressure hydrocephalus: correlation between cerebral circulation time and dementia.
Regional cerebral blood flow and regional cerebral circulation time were measured in 13 demented patients with chronic hydrocephalus, mostly normal pressure hydrocephalus.
The average hemi... | 9 |
1,676 | Value of carvedilol in congestive heart failure secondary to coronary artery disease.
Despite considerable interest in the use of beta-blocking agents in congestive heart failure (CHF), their clinical application is limited because of their negative inotropic effects.
Beta blockers with vasodilating properties may ha... | 13 |
1,702 | Hindbrain ischemia produced by bilateral vertebral artery occlusion and moderate hypotension in spontaneously hypertensive rats.
Hindbrain ischemia was induced by bilateral vertebral artery occlusion and moderate hypotension in spontaneously hypertensive rats (SHRs).
Mean arterial blood pressure was lowered to 80 mmH... | 13 |
2,361 | Biguanides and sulfonylureas as combination therapy in NIDDM.
Oral combination therapy with biguanides (metformin) and sulfonylureas is discussed.
The rationale for the use of this combination is based on the different sites of action of the two kinds of drugs and the possibility for obtaining additive or potentiatin... | 17 |
3,158 | Premenstrual syndrome: an update for the clinician.
Premenstrual syndrome is a complex disorder in which a variety of symptoms can occur in the luteal phase of the menstrual cycle.
The symptoms should occur each cycle only from the time near ovulation to soon after the onset of menses.
There should be at least 1 wee... | 22 |
174 | Effect of intraarterial versus intravenous cisplatin in addition to systemic doxorubicin, high-dose methotrexate, and ifosfamide on histologic tumor response in osteosarcoma (study COSS-86).
In osteosarcoma, intraarterial (IA) administration of systemic treatment has been advocated to improve local tumor response prep... | 3 |
941 | Breathing exercises for the medical patient: the art and the science.
The art of breathing exercises can be traced to the late 1800s.
In the past 10 years, the increased demand for treatment for respiratory muscle failure of dysfunction has resulted in numerous studies evaluating methods of treatment or training.
Th... | 7 |
2,587 | Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics.
Several short-term studies have shown that inhaled steroids can reduce airway hyper-responsiveness in asthma.
To evaluate whether prolonged treatment can brin... | 19 |
3,212 | Chloroprocaine antagonism of epidural opioid analgesia: a receptor-specific phenomenon?
Sixty healthy patients scheduled for elective cesarean delivery under epidural anesthesia were randomized to receive either lidocaine or 2-chloroprocaine as the primary local anesthetic agent.
When patients first complained of pos... | 22 |
3,316 | Molecular characterization of inherited medium-chain acyl-CoA dehydrogenase deficiency.
Deficiency of medium-chain acyl-CoA dehydrogenase (MCAD) is a common inherited defect in energy metabolism.
Characterization of the mRNA encoding MCAD in a Dutch MCAD-deficient patient revealed an A----G change at nucleotide posit... | 22 |
1,959 | The relationship between sex hormones and high-density lipoprotein cholesterol levels in healthy adult men.
The objective of this study was to clarify the complex and uncertain relationship between endogenous sex hormones and high-density lipoprotein (HDL) cholesterol levels in healthy men.
Fifty-five healthy adult m... | 13 |
1,930 | Molecular biology in cardiology: recent developments and opportunities for clinical applications.
The revolution in molecular biology that has taken place in the last decade has provided powerful research methods that are changing our understanding of cardiovascular physiology and disease.
This editorial commentary w... | 13 |
3,010 | A comparison of hospital costs and morbidity between octogenarians and other patients undergoing general surgical operations.
The hospital costs and clinical results of 304 patients who were more than 80 years old and who underwent general surgical procedures were evaluated.
The over-all mortality rate was 14 per cen... | 22 |
109 | Parents' vs physicians' utilities (values) for clinical outcomes in potentially bacteremic children.
Our previous analyses of decision strategies in children 3-24 months with acute-onset fever greater than or equal to 39 degrees C and no evident bacterial focus of infection indicated that the risks of routine blood cu... | 0 |
808 | Physicochemical determinants of in vitro shock-wave biliary lithotripsy.
Human gallstones were studied by visual inspection, computerized tomographic imaging, and chemical analysis to assess physicochemical characteristics that may determine the outcome of in vitro shock-wave fragmentation.
Eighty-five stones (mean d... | 5 |
1,733 | Blood pressure response to dietary calcium intervention in humans.
Epidemiological and experimental studies have suggested that dietary calcium deficiency may lead to the development of hypertension.
This article reviews findings in human trials on calcium intervention with special reference to the responses of blood... | 13 |
3,097 | Late onset adrenal hyperplasia: mutation at codon 282 of the functional 21-hydroxylase gene is not ubiquitous.
Ten patients affected with 21-hydroxylase (21-OH) deficient late-onset adrenal hyperplasia were studied to determine the prevalence of a mutation at codon 281 of the functional 21-OH gene (CYP21B) that result... | 22 |
3,199 | Postmortem chorionic villus sampling is a better method for cytogenetic evaluation of early fetal loss than culture of abortus material.
In utero chorionic villus sampling at the time of diagnosis of intrauterine fetal death is compared with more traditional use of cultured fetal skin, products of conception, or amnio... | 22 |
488 | Can internal mammary chain treatment decrease the risk of death for patients with medial breast cancers and positive axillary lymph nodes?
The effect of internal mammary chain treatment on each type of malignant death-related event was analyzed in 1195 patients with operable breast cancer and histologically involved a... | 3 |
3,181 | Rejection of multivisceral allografts in rats: a sequential analysis with comparison to isolated orthotopic small-bowel and liver grafts.
Multivisceral isografts and allografts were transplanted to Lewis rats, and the histopathologic changes were studied in the liver, intestine, and other constituent organs.
Rats rec... | 22 |
787 | Esophageal reflux before and after isolated myotomy for achalasia.
Four patients with achalasia underwent 24-hour esophageal pH measurements as ambulatory patients before and after limited myotomy without fundoplication.
Resting lower esophageal sphincter pressure was reduced from 24.3 +/- 1.3 mm Hg to 7.5 +/- 4.3 mm... | 5 |
1,293 | Learning curve for radial keratotomy.
I prospectively evaluated my own learning curve for radial keratotomy (RK) by comparing the results achieved in two groups: 20 consecutive eyes on which I performed RK without having had previous experience with the procedure (group 1); and 20 other eyes, matched for age, sex, and... | 10 |
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