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2,940 | Anterior cruciate ligament injury: evaluation of intraarticular reconstruction of acute tears without repair. Two to seven year followup of 155 athletes
To evaluate the effectiveness of our treatment regimen, we retrospectively studied the surgically treated knees of 155 athletes, aged 15 to 42 years, who had sustain... | 20 |
933 | Treatment of small-cell lung cancer with an alternating chemotherapy regimen given at weekly intervals: a Southwest Oncology Group pilot study.
We designed an intensive, weekly treatment regimen for patients with small-cell lung cancer (SCLC) using six of the most active chemotherapeutic agents for this disease (doxor... | 7 |
74 | The inactivation of antithrombin III by serum elastase in patients with surgical infections.
The relationship between serum elastase and antithrombin III was determined in septic surgical patients as a possible mechanism for intravascular thrombosis and hypercoagulability during sepsis.
Eighteen patients with surgica... | 0 |
466 | Hepatic tumors: signal enhancement at Doppler US after intravenous injection of a contrast agent.
Experiments were carried out to detect and establish the origin of Doppler and echo signal enhancement in small vessels of the systemic circulation and of tumors after intravenous injection of a contrast agent.
Eight woo... | 3 |
718 | "Healed" experimental gastric ulcers remain histologically and ultrastructurally abnormal.
The present study was designed to assess histologic and ultrastructural features of gastric mucosa in the areas of grossly healed ulcers (acetic acid-induced gastric ulcers) in rats.
The specific question we studied was whether... | 5 |
3,346 | Patterns of dyspepsia in patients with no clinical evidence of organic diseases.
We studied 2000 dyspeptic patients with no obvious signs of organic disease at their first examination, in order to (1) verify how many diagnoses of idiopathic dyspepsia had really been made after exhaustive diagnostic procedures and (2) ... | 22 |
231 | Local recurrence after curative resection of colorectal adenocarcinoma.
A total of 853 patients with 861 colorectal adenocarcinomas were operated on at our institution between 1965 and 1981.
Complete follow-up information was obtained in all but six patients (99.4%), and all available histologic slides were reviewed ... | 3 |
761 | Crohn's disease: what about the pancreas? [editorial]
Crohn's disease (CD) is now accepted as a systemic illness.
The importance of extraintestinal manifestations is underlined by the fact that such "complications" can be more prominent and even more difficult to control than the intestinal disease itself.
Lately, e... | 5 |
2,932 | Foley catheter balloon puncture and the risk of free fragment formation.
The incidence of free fragment formation following balloon puncture or spontaneous bursting was examined in 294 Foley catheters immersed for 48 h in urine.
The catheters were divided into 3 groups: 100 were inflated to the manufacturer's recomme... | 20 |
2,376 | Insulinomimetic properties of trace elements and characterization of their in vivo mode of action.
Lithium and vanadate have insulinomimetic actions in vitro.
In this study, we examined the in vivo effects of lithium and vanadate on glucose metabolism in diabetic (90% partial pancreatectomy) rats.
Four groups of chr... | 17 |
835 | Increasing prevalence of gallstones in male veterans with alcoholic cirrhosis.
Cases of alcoholic cirrhosis identified at necropsy were studied for the prevalence and type of gallstones, compared with age- and race-matched autopsy controls.
Data were examined from 1970-1977 and 1980-1987.
In the early sample of 460 ... | 5 |
957 | The rise of tuberculosis in America before 1820.
Bills of mortality, newspaper and gazette articles, journals, and other records with specific references to "consumption," "phthisis," and other terms for tuberculosis were reviewed to determine the occurrence and importance of tuberculosis in the American colonies befo... | 7 |
3,310 | Loss of photosynthetic and chlororespiratory genes from the plastid genome of a parasitic flowering plant.
Photosynthesis is the hallmark of plant life and is the only plastid metabolic process known to be controlled by plastid genes.
The complete loss of photosynthetic ability, however, has occurred on several indep... | 22 |
338 | Changes in the clearance of total and unbound etoposide in patients with liver dysfunction.
The disposition of total and non-protein-bound etoposide was investigated in 21 cancer patients receiving etoposide and cisplatin combination chemotherapy.
Etoposide plasma concentrations were determined using a specific high-... | 3 |
593 | The influence of growth hormone on the reversibility of articular cartilage degeneration in rabbits.
Growth hormone has chondrogenic affects on normal as well as on damaged articular cartilage.
In this study, the influence of growth hormone is investigated on early degenerative changes in the articular cartilage in 7... | 4 |
2,432 | Impaired growth hormone (GH) response to pyridostigmine in type 1 diabetic patients with exaggerated GH-releasing hormone-stimulated GH secretion.
In the present study we investigated the effects of the acetylcholinesterase inhibitor pyridostigmine (PD), which is hypothesized to decrease hypothalamic somatostatin tone... | 17 |
597 | Open transpedicular biopsy of the vertebral body.
We describe a method of obtaining a biopsy from the body of a vertebra by an open transpedicular route.
This minimises the danger of contamination of tissue planes and spaces.
| 4 |
456 | The melanocyte and melanoma.
This paper reviewed some of the interesting biological aspects of melanocytes and their relationship to the nevus and to melanoma.
It also proposed a rationale for "adequate" surgery in the management of melanoma according to level, depth, margins, and trends in treatment.
These proposit... | 3 |
926 | A placebo-controlled trial of immunotherapy with two extracts of Dermatophagoides pteronyssinus in allergic rhinitis, comparing clinical outcome with changes in antigen-specific IgE, IgG, and IgG subclasses.
A double-blind, placebo-controlled trial of immunotherapy was conducted in patients with Dermatophagoides ptero... | 7 |
781 | Interventional radiology of the biliary tract. Transcholecystic intervention.
Diagnostic and therapeutic biliary intervention by percutaneous access to the gallbladder is an important new area in interventional radiology.
The anatomy of the gallbladder, biliary tree, and surrounding viscera is reviewed in this articl... | 5 |
3,011 | Effects of medical and surgical treatment on cerebral perfusion and cognition in patients with chronic cerebral ischemia.
The effects of medical treatment with and without cerebral revascularization procedures on cognition and cerebral blood flow were compared among 36 patients with extracranial occlusive cerebrovascu... | 22 |
1,933 | The Framingham Disability Study: relationship of various coronary heart disease manifestations to disability in older persons living in the community.
The relation between coronary heart disease and disability was examined in 2,576 community-dwelling women and men ages 55-88 years.
These Framingham Study participants... | 13 |
20 | Congenital insensitivity to pain with neuroparalytic keratitis.
Congenital insensitivity to pain is a well-defined entity in the group of sensory deficiency syndromes.
To the best of our knowledge, unilateral neuroparalytic keratitis associated with congenital insensitivity to pain has not been reported.
We report s... | 0 |
629 | Radical osteoclastic craniectomy in sagittal synostosis
We report our experience in the surgical treatment of sagittal synostosis using radical osteoclastic craniectomy in 60 consecutive patients.
After surgery in children aged 6 months or younger (Group I), reossification usually started 2 weeks postoperatively and... | 4 |
3,035 | Effect of recombinant hirudin, a specific inhibitor of thrombin, on endotoxin-induced intravascular coagulation and acute lung injury in pigs.
We hypothesized that thrombin activation may play a prominent role in endotoxin-induced secondary organ failure, such as acute lung injury.
To test this hypothesis, we adminis... | 22 |
1,596 | Natural history of hypertrophic cardiomyopathy in the elderly.
The prognosis of patients diagnosed as having hypertrophic cardiomyopathy at advanced age has not been well defined.
This study details follow-up information obtained for 95 patients initially diagnosed as having hypertrophic cardiomyopathy at age greater... | 13 |
1,909 | Application of time series analysis to circadian rhythms: effect of beta-adrenergic blockade upon heart rate and transient myocardial ischemia.
Circadian variations of transient myocardial ischemia and heart rate have been identified, but the rhythms and their response to beta blockade have not been fully characterize... | 13 |
1,873 | Intraoperative transesophageal color-coded Doppler echocardiography for evaluation of residual regurgitation after mitral valve repair.
Because mitral valve competence after mitral valve reconstruction is awkward to assess during this procedure, we evaluated in this respect transesophageal color-coded Doppler echocard... | 13 |
897 | External detection of pulmonary accumulation of indium-113m labelled transferrin in the guinea pig.
Accumulation of radioisotope labelled transferrin in the lungs of guinea pigs was determined with an external detection system.
The method is based on the intravascular and extravascular distribution of indium-113m lab... | 7 |
1,485 | Adenomyosis in Pakistani women: four year experience at the Aga Khan University Medical Centre, Karachi.
As part of a quality assurance programme at the Aga Khan University Medical Centre, Karachi, Pakistan, all hysterectomy specimens were reviewed from January 1986 to December 1989.
Adenomyosis was found in 237 of t... | 12 |
3,318 | Inactivation of human alpha-globin gene expression by a de novo deletion located upstream of the alpha-globin gene cluster.
Synthesis of normal human hemoglobin A, alpha 2 beta 2, is based upon balanced expression of genes in the alpha-globin gene cluster on chromosome 16 and the beta-globin gene cluster on chromosome... | 22 |
2,321 | Uroporphyrinogen decarboxylase: a splice site mutation causes the deletion of exon 6 in multiple families with porphyria cutanea tarda.
Uroporphyrinogen decarboxylase (URO-D) is a cytosolic heme-biosynthetic enzyme that converts uroporphyrinogen to coproporphyrinogen.
Defects at the uroporphyrinogen decarboxylase loc... | 16 |
2,245 | Autologous mixed lymphocyte reaction is reduced in patients with psoriasis.
The autologous mixed lymphocyte reaction (auto-MLR) was studied to test the interactions between immunocompetent cells in patients with psoriasis.
The auto-MLR in 20 patients with psoriasis was significantly lower than in 16 normal controls.
... | 16 |
1,023 | Epstein-Barr virus-related antibody. Changes in titers after therapy for nasopharyngeal carcinoma.
Using long-term follow-up data from a prospective, collaborative study of 182 North American patients, we evaluated the significance of various serologic tests for antibody to Epstein-Barr virus in predicting outcome aft... | 8 |
2,718 | Stereotactic biopsy of an active multiple sclerosis lesion. Immunocytochemical analysis and neuropathologic correlation with magnetic resonance imaging.
Stereotactic biopsy of an active multiple sclerosis lesion in a 23-year-old patient with unilateral symptoms and an isolated high-signal-intensity magnetic resonance ... | 19 |
2,629 | Gallium-67 imaging: a predictor of residual tumor viability and clinical outcome in patients with diffuse large-cell lymphoma.
Durable complete remissions (CRs) can be achieved in patients with diffuse large-cell lymphoma (DLCL) with multidrug chemotherapy.
The length of time to reach CR may be predictive of treatmen... | 19 |
3,099 | Intravenous but not intracolonic epidermal growth factor maintains colonocyte proliferation in defunctioned rat colorectum.
The role of epidermal growth factor in the proliferation of normal and premalignant colonocytes in vivo is not fully understood.
In particular, the relative importance of its possible systemic a... | 22 |
937 | Current epidemiology of pertussis in Japan.
Since the introduction of whole cell pertussis vaccine into general use as part of the routine immunization in 1947 under the Preventive Immunization Law, a steady decrease in reported cases of pertussis was noted until 1974.
At that time the number of reported cases reache... | 7 |
947 | Treatment of atelectasis of upper lung lobes. Selective bronchial suctioning with J-shaped catheter tip and guide mark.
We developed a technique for blind bronchial suction using a curved-tip catheter with a guide mark, for the treatment of atelectasis of the lower and middle lobes of the lung.
Suction of the upper l... | 7 |
3,353 | Short-term and long-term changes in renal function after donor nephrectomy.
We retrospectively examined the effect of nephrectomy on renal function in 55 living related donors.
Renal function was measured with 131iodine-orthoiodohippurate scans.
All patients were studied preoperatively, and 1 week and 1 year postope... | 22 |
2,246 | Pentoxifylline inhibits the proliferation of human fibroblasts derived from keloid, scleroderma and morphoea skin and their production of collagen, glycosaminoglycans and fibronectin.
Pentoxifylline, an analogue of the methylxanthine theobromine, inhibits the proliferation and certain biosynthetic activities of fibrob... | 16 |
2,354 | Impact of intensive educational approach to dietary change in NIDDM.
The aim of this study was to compare the effects of an intensive educational approach incorporating longer time, greater simplicity, repetition, and cognitive motivational techniques with a conventional one in subjects with established non-insulin-de... | 17 |
1,298 | Uremic platelets have a functional defect affecting the interaction of von Willebrand factor with glycoprotein IIb-IIIa.
Uremic patients have an impaired platelet function that has been related to membrane glycoprotein (GP) abnormalities.
Using a perfusion system, we have studied the interaction of normal and uremic ... | 11 |
2,709 | AIDS, minority patients, and doctors: what's the risk? Who's talking?
We asked 39 physicians providing primary care for a mostly minority patient population to respond to a questionnaire concerning their attitudes and behavior toward AIDS risk assessment and preventive counseling and to indicate their beliefs concerni... | 19 |
2,593 | Macrophage tropism of HIV-1.
Both in vivo and in vitro studies clearly demonstrate that cells of the mononuclear phagocyte lineage are major hosts for human immunodeficiency virus type 1 (HIV-1) replication.
Presumably these cells play a key role in the pathogenesis of acquired immunodeficiency syndrome (AIDS).
To f... | 19 |
1,728 | From the parallel group design to the crossover design, and from the group approach to the individual approach.
The consequences of heterogeneity in response to antihypertensive drugs for the clinical development programs of new antihypertensive drugs and for the care of the individual hypertensive patient have not pr... | 13 |
2,789 | Mortality following hip fracture before and after implementation of the prospective payment system.
Recent studies of patients with hip fractures from two hospitals have suggested that the marked reduction in length of stay that occurred following implementation of the Medicare prospective payment system (PPS) resulte... | 20 |
2,676 | Virologic and immunologic aspects of acquired immunodeficiency syndrome.
From the initial clinical descriptions of the acquired immunodeficiency syndrome (AIDS) in 1981 to the present time, much has been discovered concerning the epidemiologic factors, pathogenesis, treatment and prevention of this disease.
Recent ad... | 19 |
3,323 | Flumazenil in ketamine and midazolam anaesthesia.
A double-blind, parallel group study using flumazenil and placebo was carried out to determine whether patients who received flumazenil would awake more quickly and whether this drug would reverse the protection conferred by midazolam on the psychic sequelae of ketamin... | 22 |
1,682 | Mechanical factors in large artery disease and antihypertensive drugs.
Hypertension may induce early alterations in large arteries by 2 mechanical stresses: one related to intravascular pressure, the other to blood flow dynamics.
Distending pressure force acts in a circumferential direction, inducing decreased arteri... | 13 |
1,745 | Calcium and contractile responses to phorbol esters and the calcium channel agonist, Bay K 8644, in arteries from hypertensive rats.
This study examined the calcium dependency of contractions in arteries from rats made hypertensive by aortic coarctation and in rats with genetic hypertensive (stroke-prone spontaneously... | 13 |
1,979 | Increased endothelin in experimental heart failure.
Recent studies demonstrate that endothelin, a potent endogenous vasoconstrictor peptide, circulates in plasma of normal animals and humans.
However, the role of this peptide in pathophysiological states remains unclear.
The present study was designed to test the hy... | 13 |
2,619 | Salsalate cross-sensitivity in aspirin-sensitive patients with asthma.
Ten aspirin (ASA)-sensitive patients with asthma underwent double-blind, placebo-controlled oral challenges with salsalate followed by ASA-sensitive confirmatory challenges.
All 10 patients sustained asthmatic reactions to ASA, but only two develo... | 19 |
1,796 | Is adenosine 5'-triphosphate derangement or free-radical-mediated injury the major cause of ventricular dysfunction during reperfusion? Role of adenine nucleoside transport in myocardial reperfusion injury.
The aim of this study was to determine the dual role of ATP as an energy substrate and as a major source of oxyg... | 13 |
2,600 | Zidovudine (Retrovir) update.
Zidovudine (AZT) is the first antiretroviral agent to be licensed for the treatment of human immunodeficiency virus (HIV) infection.
Since the initial placebo-controlled trial showing improved survival among patients with acquired immunodeficiency syndrome (AIDS) or symptomatic HIV infec... | 19 |
2,169 | Sickle erythrocytes inhibit human endothelial cell DNA synthesis.
Patients with sickle cell anemia experience severe vascular occlusive phenomena including acute pain crisis and cerebral infarction.
Obstruction occurs at both the microvascular and the arterial level, and the clinical presentation of vascular events i... | 14 |
513 | Human recombinant GM-CSF in allogeneic bone-marrow transplantation for leukaemia: double-blind, placebo-controlled trial.
In a randomised, double-blind trial 20 patients with leukaemia received human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) and 20 received placebo, for 14 days after alloge... | 3 |
1,572 | Orthostatic hypotension following right ventricular myocardial infarction corrected with mineralocorticoid therapy.
Severe hypotension while standing became a problem in a patient after discharge from the hospital following right ventricular myocardial infarction.
Hemodynamic studies showed that right ventricular sys... | 13 |
108 | Prevention of infection in a porous tracheal prosthesis by omental wrapping.
The ideal tracheal prosthesis has to permit complete incorporation by epithelialization of the luminal surface.
This is not possible with the currently available impermeable solid silicone tube.
The authors developed a reinforced, porous po... | 0 |
140 | Ascariasis.
Ascaris lumbricoides is the most common helminth to infect humans.
Infection occurs when contaminated soil containing mature eggs is swallowed.
Clinically, infection ranges from the asymptomatic carrier state to life-threatening pulmonary disease or intestinal obstruction.
Diagnosis is most frequently e... | 2 |
2,418 | Change in hexose distribution volume and fractional utilization of [18F]-2-deoxy-2-fluoro-D-glucose in brain during acute hypoglycemia in humans.
We used positron emission tomography (PET) to study the effects of mild hypoglycemia on cerebral glucose uptake and metabolism.
Nine healthy men were studied under basal sa... | 17 |
330 | Lymphokine-activated killer (LAK) cells. V. 8-Mercaptoguanosine as an IL-2-sparing agent in LAK generation.
Guanine ribonucleosides, substituted at the C8 position with either a bromine or a thiol group, have recently been shown to regulate several immunologic responses.
We have previously shown that 8-mercaptoguanos... | 3 |
1,310 | Epidemiology of prostate cancer.
Available epidemiologic data do not allow targeting of specific populations for prostate cancer screening or early detection programs.
Although certain strong factors have been identified (age, race, location), none sufficiently defines high-risk groups in whom recommendations should ... | 11 |
387 | Basement membrane of cervical adenocarcinoma: an immunoperoxidase study of laminin and type IV collagen.
The basement membrane components type IV collagen and laminin were examined immunohistochemically in 14 cases of adenocarcinoma of the cervix.
The patterns of staining in adenocarcinoma in situ, invasive adenocarc... | 3 |
2,545 | Advanced protein glycosylation induces transendothelial human monocyte chemotaxis and secretion of platelet-derived growth factor: role in vascular disease of diabetes and aging.
Diabetes and aging are commonly accompanied by arterio- and atherosclerosis.
Infiltration of the arterial subendothelial intima by macropha... | 18 |
873 | The role of herpes simplex virus in the development of oral mucositis in bone marrow transplant recipients.
Herpes simplex virus (HSV) has been implicated as a major etiologic factor in the development of ulcerative mucositis in bone marrow transplant (BMT) recipients.
In this study, 60 patients who received BMTs wer... | 6 |
3,238 | Effect of nontransmural necrosis on epicardial potential fields. Correlation with fiber direction.
The effect of nontransmural necrosis on epicardial potential distributions was studied in 13 dogs.
In previous studies, left ventricular epicardial pacing generated epicardial potential maps at QRS onset with a negative... | 22 |
638 | Computer-assisted tomography of scoliosis operated with or without Harrington's rod. Biomechanics aspects of the fusion.
Forty-eight cases of posterior vertebral arthrodesis for scoliosis, performed with or without instrumentation, were examined using computed tomography (CT) scanning to study the evolving fusion mass... | 4 |
283 | Cell lineage markers in human pancreatic cancer.
The normal pancreas consists of three major cell types or lineages that share a common embryologic origin from pluripotent endodermal precursors.
The type of cell that undergoes neoplastic transformation to form a pancreatic carcinoma is controversial and may influence... | 3 |
2,482 | Tumor necrosis factor-increased hepatic very-low-density lipoprotein production and increased serum triglyceride levels in diabetic rats.
Previous studies demonstrated that administration of tumor necrosis factor (TNF) to diabetic rats rapidly increases serum triglyceride levels and stimulates hepatic lipogenesis with... | 17 |
1,338 | Treatment of outflow tract obstruction due to benign prostatic hyperplasia with the pollen extract, cernilton. A double-blind, placebo-controlled study.
Whilst prostatectomy remains the "gold standard" for the treatment of outflow tract obstruction due to benign prostatic hyperplasia, medical treatment--if only for sy... | 11 |
1,545 | Ultrasonic integrated backscatter two-dimensional imaging: evaluation of M-mode guided acquisition and immediate analysis in 55 consecutive patients.
We have shown previously that cardiac cycle-dependent integrated backscatter characterizes the physical state of myocardium in patients with ischemic heart disease and c... | 13 |
2,236 | A total artificial heart for neonates allowing bridging to transplantation.
Since the early 1980s, a rapid increase in successful pediatric heart transplantation has improved the chance of survival for many children suffering from otherwise fatal cardiomyopathies or congenital cardiac defects.
During the last 5 years... | 15 |
369 | Mutagen sensitivity in patients with head and neck cancers: a biologic marker for risk of multiple primary malignancies.
Eighty-four patients with head and neck cancers were evaluated for in vitro sensitivity to mutagens and then followed longitudinally for development of multiple primary malignancies.
We assessed mu... | 3 |
547 | Insulin-like growth factor binding protein secretion by breast carcinoma cell lines: correlation with estrogen receptor status.
Breast tumor cell lines have been shown to secrete several distinct polypeptide growth factors, although conflicting results exist for the insulin-like growth factors (IGFs).
In contrast a l... | 3 |
1,584 | Role of angiotensin-converting enzyme inhibitors in congestive heart failure.
Conventional therapy for congestive heart failure (CHF) includes sodium-restricted diet, diuretics, digitalis, vasodilators, and short-term intravenous administration of beta-adrenergic agonists during episodes of decompensation.
A specific... | 13 |
2,474 | Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
The current studies were designed to determine whether chronic overexpression of low density lipoprotein (LDL) receptors in the liver would protect mice from the increase in plasma LDL-cholesterol that is induced by high-fat diet... | 17 |
3,285 | Transsynaptic degeneration in the superficial dorsal horn after sciatic nerve injury: effects of a chronic constriction injury, transection, and strychnine.
The lumbar and cervical spinal dorsal horns of adult rats with a chronic (8 days) constriction injury of the sciatic nerve on one side (and a sham operation on th... | 22 |
1,414 | Treatment with desmopressin in severe nocturnal enuresis in childhood.
A series of 22 patients with severe nocturnal enuresis were treated with desmopressin in a randomised double-blind cross-over study.
Treatment with 20 and 40 micrograms was highly effective compared with placebo.
No difference in dry nights was f... | 11 |
1,504 | Human oocyte and preembryo donation: an evolving method for the treatment of infertility.
The utilization of oocyte and preembryo donation in the treatment of infertility has recently expanded.
Since 1983, modifications in the retrieval of donated female gametes have enhanced both the safety and the efficacy of the p... | 12 |
3,017 | Clinical significance of white cell antibodies in febrile nonhemolytic transfusion reactions.
Febrile nonhemolytic transfusion reactions (FNHTRs) are associated with white cell (WBC) antibodies.
The purposes of this study were to determine the frequency of WBC antibodies, to associate the severity of reactions with a... | 22 |
2,603 | Immune deficiency in family members of patients with Hodgkin's disease.
Indirect data supporting a preexisting immunologic impairment in patients with Hodgkin's disease (HD) have been presented in recent years.
These immunologic defects are supposed to be related to genetic and/or environmental factors.
In this stud... | 19 |
3,337 | Effects of prostaglandin I2, superoxide dismutase, and catalase on ischemia-reperfusion injury in liver transplantation.
This study evaluated the effects of a prostaglandin I2 analogue (aPGI2), superoxide dismutase (SOD), and catalase (CAT) on hepatic injury after warm ischemia and reperfusion in terms of survival, mi... | 22 |
738 | Pharmacokinetics of propofol infusions in patients with cirrhosis.
We have compared the pharmacokinetics of propofol as an infusion in 10 control and 10 patients with cirrhosis.
Anaesthesia was induced within 3-4 min during administration of an infusion of propofol 21 mg kg-1 h-1.
After 5 min, the infusion was decre... | 5 |
1,581 | Interleukin-2 does not attenuate hypertension in spontaneously hypertensive rats.
It was recently reported that interleukin-2, when administered as a single bolus injection (5,000 units/kg), could prevent the development of hypertension in young spontaneously hypertensive rats and lower blood pressure to normotensive ... | 13 |
3,191 | Neurodevelopmental performance of very-low-birth-weight infants with mild periventricular, intraventricular hemorrhage. Outcome at 5 to 6 years of age.
The neurodevelopmental outcome of 38 very-low-birth-weight neonates (birth weight, less than 1501 g) was followed up prospectively from birth to 5 to 6 years of age to... | 22 |
2,883 | Effects of individually motivating smoking cessation in male blue collar workers.
Adverse demonstrable health effects linked to the individual's smoking were shown to 2,689 American workers to motivate cessation during routine examinations to detect asbestosis.
This intervention was evaluated six to 25 months later b... | 20 |
856 | Premolarization of a fractured maxillary first molar: a multidisciplinary treatment.
The diagnosis and treatment of a fractured maxillary first molar are described in this case report of a 28-year-old male.
Successful treatment of the retained palatal root of the fractured molar, referred to as premolarization, ensue... | 6 |
296 | Impaired production of tumor necrosis factor in breast cancer.
Spontaneous and lipopolysaccharide (LPS)-induced production of tumor necrosis factor (TNF) by peripheral blood macrophages was investigated in breast cancer.
Whereas spontaneous TNF production by macrophages derived from patients with breast cancer was co... | 3 |
2,250 | Contact allergy due to colophony (VI). The sensitizing capacity of minor resin acids and 7 commercial modified-colophony products.
3 minor resin acids and 7 commercial modified-colophony products of different origins were studied by experimental sensitization by means of a modified FCA method.
All 3 resin acids were ... | 16 |
1,194 | A limited diagnostic investigation for obstructive sleep apnea syndrome. Oximetry and static charge sensitive bed.
A simplified sleep apnea investigation consisting of combined oximetry and respiration movement monitoring was compared with conventional polysomnography.
These two types of recordings were performed sim... | 9 |
1,046 | Acute and long-term changes in serum lipids after acute stroke.
We studied serum lipid profiles in 171 patients less than or equal to 48 hours after the onset of acute stroke and 3 months later.
The 83 patients suffering cerebral infarction had significantly higher serum concentrations of total cholesterol, low densi... | 9 |
2,620 | Aberrant regulation of IL-1 expression in macrophages from young autoimmune-prone mice.
IL-1 is a multifunctional, immunoregulatory polypeptide produced by many cell types.
Because activated macrophages are a major source of IL-1 and have also been implicated in the pathogenesis of autoimmune disease, we investigated... | 19 |
2,925 | The use of intestinal antibiotics to delay or prevent infections in patients with burns.
Bacterial colonization and infection of wounds in seriously burned patients often comes from the patient's indigenous bowel flora.
A prospective randomized clinical trial that involved 30 patients with 20% or greater total body s... | 20 |
2,254 | Cultured epidermal autografts and allografts: a study of differentiation and allograft survival.
Cultured epidermal sheets were examined before and at various times after grafting on skin ulcer beds.
Before grafting, the sheet consisted of four to five layers of keratinocytes with incomplete differentiation.
Ten day... | 16 |
1,774 | Ten-year follow-up of survival and myocardial infarction in the randomized Coronary Artery Surgery Study
The Coronary Artery Surgery Study (CASS) randomized 780 patients to an initial strategy of coronary surgery or medical therapy.
Of medically randomized patients, 6% had surgery within 6 months and a total of 40% ... | 13 |
1,732 | Calcium and blood pressure. An epidemiologic perspective.
We reviewed the research literature on the epidemiologic relationship between blood pressure levels and calcium, with an emphasis on dietary intake.
A conceptual framework for causal inference is summarized; then the designs and results of observational and in... | 13 |
2,142 | Social integration of the older thalassaemic patient.
Because social policy favours the fullest possible social integration of chronically ill patients, we have evaluated the facilities that are needed to achieve this for patients with beta thalassaemia major in the light of the therapeutic advances that now permit th... | 14 |
2,403 | Low-dose lovastatin safely lowers cholesterol after cardiac transplantation.
Hypercholesterolemia occurs in many cardiac transplant patients and may aggravate graft coronary arteriopathy as well as contributing to peripheral vascular disease.
Lovastatin, which inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase,... | 17 |
1,263 | Unusual exudative retinal detachment 9 months after scleral buckling surgery.
A 49-year-old man developed exudative retinal detachment 9 months after uncomplicated scleral buckling surgery in the left eye.
The subretinal exudates were strictly localized along the buckle and showed remarkable response to steroid.
The... | 10 |
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