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Lipoxins synthesized from arachidonic acid act by?
Ans. is 'a' i.e., Decrease leucocyte migration, adhesion, chemotaxis Effects of lipoxins (LXA4, LXB4 ) are :? Inhibit neutrophil chemotaxis and leukocyte recruitment (major action). Vasodilatation Promote moncytic phagocytosis of apoptotic neutrophils.
1
Decrease leucocyte migration, adhesion, chemotaxis
Increase leucocyte migration, adhesion, chemotaxis
Vasoconstrictio
Increased vascular permeability
Pathology
null
13444a4c-1055-49e9-8a2a-dbecda84bb9e
single
A male neonate develops small-bowel obstruction due to malrotation of the midgut segment. An x-ray of the abdomen confirms the presence of small-bowel obstruction (Figure below). He undergoes an emergency laparotomy, untwisting of the malrotated intestines, and partial small-bowel resection for intestinal infarction. W...
The small intestine arises from the midgut segment. The midgut segment extends between the ampulla of Vater and the distal transverse colon. It enters the physiological umbilical hernia at sixth week and returns to the peritoneal cavity by the tenth week. The Vitello intestinal tract (site from which Meckel's diverticu...
1
It is derived entirely from the midgut.
In the fetus, it enters the physiologic umbilical hernia in the fifth month.
It remains in the physiologic hernia for 4 months.
It is attached to the urachus.
Surgery
Small & Large Intestine
03386868-6ec3-4f61-85bc-f94e526bf9c8
multi
This law of plethysmography explains principle of working in
The  law of plethysmography explains working of pulse oximeter.
2
Capnography
Oximetry
CVP monitor
Entropy
Anaesthesia
null
85653cea-0e58-4fef-9bc5-ceaed11485eb
single
Colovesical fistula
Colovesical fistulaA colovesical fistula is the presence of a communication between the lumen of the CausesDiveiculitis:Crohn&;s disease: ~ 10%RadiotherapyTraumaClinical presentationRadiographic featuresIn most instances, the diagnosis is suspected clinically due to pneumaturia, faecaluria, recurrent urinary tract infe...
1
Most commonly presents with pneumaturia
More common in females
Most commonly caused by colon cancer
Readily diagnosed on barium enema
Pathology
All India exam
219f25f9-a2e8-489c-981a-71bb8f2ef5ce
single
Features of vernal conjunctivitis are:
Ans. A, B and C
4
Shield ulcer
Horner-Tranta's spots
Papillary hyperophy
All
Ophthalmology
null
6ceff5be-a22d-40b5-8918-039f0dec1daf
multi
Prostaglandin was discovered from -
Ans. is 'c' i.e.. Seminal fluid "The name prostaglandin comes from the prostate gland. When prostaglandin was first isolated from seminal fluid, it was believed to have been added from the prostate. "
3
Tear
Saliva
Seminal fluid
Blood
Physiology
Endocrinology metabolism
b31036f6-76a7-426f-a3e5-14d1a241c545
single
Ocriplasmin is the newer drug used in which of the following?
Ocriplasmin is used as chemical vitrectomy - it liquifies the gel like vitreous thereby relieving any vitreous traction. Hence used to relieve vitreo-macular traction which when significant can progress to idiopathic macular hole New Drugs Ocriplasmin: Chemical vitrectomy. Anti- VEGF Bevacizumab: Avastin Pegitinib- Mac...
2
Retinal break
Vitreomacular traction
Submacular blees
Diabetic macular bleed
Ophthalmology
Diagnosis and Treatment of Retina
509a4408-abbf-4680-881e-80b903e609fe
single
A 28-year-old woman recently treated as an outpatient for pelvic inflammatory disease presents with fever, leukocytosis, and deep rectal pain. In which space is this lesion? SELECT ONE.
Supralevator abscesses are relatively rare. Most patients have a pelvic inflammatory condition such as salpingitis, diverticulitis or Crohn's, or have had recent pelvic surgery.
1
Supralevator space
Perianal space
Levator ani muscle
Intermuscular space
Surgery
Small & Large Intestine
34502f13-a391-41c2-b911-700c45837236
single
The ideal muscle relaxant used for a neonate undergoing porto-enterostomy for biliary atresia is:
Ans. is 'a' i.e. Atracurium In this case a muscle relaxant is required whose metabolism has nothing to do with liver (because liver is damaged in biliary' atresia)So Atracurium is the muscle relaxant of choice as it is inactivated in plasma by spontaneous non enzymatic degradation. (Hoffman elimination) so its duration...
1
Atracurium.
Vecuronium
Pancuronium.
Rocuronium.
Anaesthesia
Muscle Relaxant
795b9963-c689-488f-a19c-70e86c284748
single
VAT in mechanical ventilation stands for -
Ans. is 'c' i.e., Ventilator associated tracheobronchitis o VAT (Ventilator associated tracheabronchitis) & VAP (Ventilator associated pneumonia) are nosocomial lower respiratory tract infections common in patients who are on ventilator for long periods of time.Adverse effects of PEEP/CPAP1. Pulmonaryo Controlled PEEP ...
3
Ventilator associated trauma
Ventilator associated treatment
Ventilator associated tracheobronchitis
None of the above
Anaesthesia
Breathing Systems
35099039-20da-4ff4-bcff-d797af94f290
multi
Complications arising out of A - V fistula done for renal failure include the following EXCEPT -
null
4
Infection
Thrombosis
High output cardiac failure
Necrosis of the distal part
Surgery
null
01991412-4275-4d02-8536-4fe038080305
multi
Laparoscopy is best avoided in patients with :
COPD
4
Hypeension
Diabetes
Obesity
COPD
Gynaecology & Obstetrics
null
9073bec9-f54a-43e3-ae36-e18c735f8735
single
Secretion of Prolactin is affected by:
B i.e. Dopamine Dopamine acts as hypothalamic prolactin inhibiting hormoneQ and decreases prolactin secretion. L - DOPAQ Decreases prolactin release by formation of dopamine BromocriptineQ (& Dopamine agonists) Inhibits prolactin releas by stimulating dopamine receptors. ChlorpromazineQ (& Dopamine antagonist) Enhances...
2
GnRH analogue
Dopamine
Serotonin
FSH
Physiology
null
51b2105c-cfc4-4583-8fa7-63fcb54ac117
single
Muscles cannot make use of glycogen because of deficiency of :
It is because of the deficiency of Glycogen Phosphorylase. It is the first and rate-limiting enzyme of glycogenolysis. Deficiency of Glycogen phosphorylase in muscles is known as Mc Ardle's disease The other question usually asked is why muscle cannot maintain blood glucose then the answer is due to lack of enzyme gluc...
2
Glucose-6-phosphatase
Glycogen phosphorylase
Hexokinase
Phospho-gluco-mutase
Biochemistry
Glycogen
d8611a76-4d07-4215-8493-145280585e30
single
NSAID proposed to be acting via inhibition of COX–3 is :
null
2
Nimesulide
Paracetamol
Ketorolac
Rofecoxib
Pharmacology
null
3579e111-ebdf-4d14-88b8-a7f6d91d2cc2
single
Drug causing exanthema -
Ans. is 'd' i.e., All of the above \Ref: Rooks ?h/e p. 73.22-73.23]Drugs causing exanthematic reactionsMost commonLess commonAmpicillin and penicillinPhenylbutazone and other pyrazolonesSulphonamidesPhenytoinCarbamazepineGoldGentamicinMeprobamateAtropineCephalosporinsBarbituratesThiazidesNaproxenIsoniazidPhenothiazines...
4
Atropine
Phenytoin
Sulfonamide
All of the above
Skin
Autoimmune Skin Disorders
f643e4ab-6113-4ec1-b32f-f12050fe64ea
multi
Most common cause of congenital sensineuronal hearing loss -
Ans. is 'b' i.e., CMV * Cytomegalovirus - Most common viral cause of congenital viral deafness* Mumps - Most common cause viral of acquired sensorineural hearing loss.
2
Parvovirus
CMV
Rubella
Toxoplasmosis
ENT
Ear
49bc347a-38f1-4779-92e2-4e1f48cc691b
single
A patient is unable to move eye outw ard beyond midline. The lesion is in -
Ans. is c' i.e., Abducent nerve o Inability.' to move the eye outward beyond midline suggests lateral rectus palsy, which is responsible for abduction. There are six extraocular muscles in each eye.o All the extra ocular muscles are supplied by the occulomotor nerve except for the superior oblique which is supplied by ...
3
Trochlear nerve
Obturator nerve
Abducent nerve
null
Anatomy
Cranial Nerves
d59cbf8b-b830-43f0-be7b-4bec43710e76
multi
Onanism is a disorder of
Sexual detion
3
Stealing
Gambling
Sexual detion
Hair pulling
Psychiatry
null
71e90450-0376-4467-82c0-97eb83e0371f
single
In comparison to hyperplasia, hypertrophy is
Hypertrophy: Increase in size of cells. There are no new cells just bigger cells containing an increased amount of structural proteins and organelles  Hyperplasia: Increase in cell number  Both results in enlarged organ  Hyperplasia occurs in cells capable of replication Hypertrophy occurs in cells which have limited ...
2
Increase in cell size and number
Increase in cell size without increase in number
Increase in cell number without increase in size
Increase in cell size and decrease in number
Pathology
null
50e89301-5612-4790-99b7-4dc109c2aa27
single
The congenital abnormality of the ileum illustrated below
Meckel's diveiculum occurs in the ileum, usually within 30 cm of the ileocecal valve, and is present in approximately 2% of normal persons. It represents incomplete involution of the vitellointestinal duct and always arises from the antimesenteric border of the intestine. Heterotopic gastric or pancreatic tissue may be...
4
Is present in approximately 20% of normal persons
Is lined by heterotopic gastric mucosa in less than 2% of cases
Often shows mucosal ulceration
Is related to persistence of the vitellointestinal duct
Pathology
miscellaneous
2ce414f3-0807-4563-92da-fb3578989287
single
Which of the following method is used in the rapid identification of Candida:
Ans. (b) Germ tube methodRef: Microbiology by Ananthanarayan and Paniker 8th ed. /607-608* A germ tube test is a diagnostic test in which a sample of fungal spores are suspended in serum and examined by microscopy for the detection of any germ.* It is particularly indicated for colonies of white or cream color on funga...
2
Culture in solid
Germ tube method
Growing in an animal
Culture in liquid
Microbiology
Candida
85f3f942-abf8-43fb-acb5-0ca6fefca0cd
single
First spinal anaesthesia was given by -
Ans-A
1
August Bier
Sicard
Morton
Corning
Unknown
null
703c567c-3669-4ee7-8ec9-0164b26c77c7
single
Purkinje fibres are ?
Ans. is 'c' i.e., Modified cardiac muscle Conducting system of hea The conducting system is made of specialized myocardium (cardiac muscle), that is capable for initation and conduction of cardiac impulse. It has following pas : ? 1) SA node :- SA node is located in the upper pa of crista terminalis at the junction of ...
3
Modified nerve fibres
Modified smooth muscle
Modified cardiac muscle
Fibrous tissue
Physiology
null
a5939de6-6809-483d-86fa-309960f65b24
single
A 70-year-old man presented to medicine emergency with worsening cough and difficulty in breathing especially at night. On physical examination, raised JVP is noted with bipedal edema. Abdominal examination reveals hepatomegaly. USG was done which reveals hepatomegaly ms. 16.8 cm. USG guided biopsy was carried out. The...
Nutmeg liver: Centri-lobular region is depressed (cell death) with adjacent parenchymal accentuation giving this appearance. HPE: Centri-lobular hemorrhage, with variable degree of hepatocyte necrosis and drop outs. Most common cause is right hea failure (increases IVC pressure, that increases central venous pressure a...
1
Right hea failure
Hepatitis A
Riedel lobe of liver
Metabolic disease of liver.
Unknown
Integrated QBank
6793e56d-aba7-4c27-92ae-f75de5a72236
multi
National Tuberculosis Institute is located at
null
1
Bangalore
Chingelput
New Delhi
Chennai
Social & Preventive Medicine
null
a924235e-9da1-4479-a318-8e4584423e05
single
Hanging cast is used for
null
2
Radius fracture
Humerus fracture
Femur fracture
Fibula fracture
Orthopaedics
null
a217a6df-cafd-49d1-bb29-fa8b1d1dc0af
single
Drugs used in treatment of herpes simplex keratitis include all except:
Ans. Pimarcin
4
Idoxuridine 0.1%
5-Fluorouracil
Adenosine arabinoside
Pimarcin
Ophthalmology
null
c5e282ae-83a0-41a1-b188-b9d4f65ab2a5
multi
Most common organ involved in the blunt trauma of abdomen in a child is: (2014 Feb D. REPEAT)
Ans: A (Spleen) Ref Emedicine Medscape online (Pediatric Abdominal Trauma Clinical Presentation), Shah SM, Shah KS, Joshi PK, Somani RB, Gohil VB, Dakhla SM. To study the incidence of organ damage and post-operative care in patients of blunt abdominal trauma with haemoperitoneum managed by laparoscopy. J Minim Access S...
1
Spleen
Kidney
Small intestine
Liver
Unknown
null
f3b4cc3a-8972-455a-bea6-fdce6bf4ebc7
multi
Shingles is caused by:
Ans. A. VZV.a. Varicella-zoster virus (VZV) causes two distinct clinical entities: varicella (chickenpox) and herpes zoster (shingles).b. Chickenpox, a ubiquitous and extremely contagious infection, is usually a benign illness of childhood characterized by an exanthematous vesicular rash.c. With reactivation of latent ...
1
VZV
HSV
CMV
Enterovirus 70
Microbiology
Virology
3b191ae4-5aa0-4834-a7a5-2c78f109efe7
single
Ivor Lewis operation is done for
In carcinoma surgery alone is best suited to patients with disease confined to the oesophagus (T1b, T2)The most widely practiced oesophagotomy approach is the two-phase Ivor Lewis operation, especially distal tumors.Three-phase oesophagectomy (McKeown) may be more appropriate for more proximal tumours in order to achie...
1
Carcinoma oesophagus
Achalasia cardia
Hiatus hernia
GERD
Surgery
G.I.T
37a6418f-e0d8-4380-8a5b-257afa503569
single
First fluid of choice in Hypovolemic shock?
Ans. (b) Normal salineRef.: Harrison 18th ed. / 270Fluid of choice in Hypovolemic shock is Normal saline.
2
Dextran
Normal saline
Dextrose normal saline
Hartmann solution
Surgery
Shock
be7d91d1-fa17-49d8-a91c-80b459649f99
single
A 27 year old man presents with a left testicular tumor with a 10 cm retroperitoneal lymph node mass. Which of the following is the treatment of choice?
Patient in the question is presenting with a testicular tumor with retroperitoneal lymph node mass, treatment of choice in such a patient is multi agent chemotherapy followed by excision of persistent masses. A 90% cure rate is seen in stage II patients and a 70% cure rate in stage III patients receiving combination ch...
4
Radiotherapy
Chemotherapy alone
Immunotherapy with interferon and interleukin
Left high inguinal orchiectomy plus chemotherapy
Surgery
null
ca068d85-9c25-4854-890b-4cc4786c3d4f
single
Hypothyroidism in sub-himlayan region is due to deficiency of
Answer is B (Iodine): Hypothyroidism (and Endemic Goitre) in sub-himalayan region is primarily due to deficiency of iodine. 'Dietary iodine deficiency is widely prevalent in many pas of India, especially the sub-Himalayan region and is the principal cause of endemic goiter. Where the deficiency is severe, goiter, hypot...
2
Iron
Iodine
Copper
Selenium
Medicine
null
52198ebe-9106-426f-a824-48989c621887
single
In an outbreak of cholera in a village with a population of 2000, 20 cases have been reported of which 5 have died. Case fatality rate is:
Case fatality rate represents the killing power of a disease.  It is  simply the  ratio of deaths to cases. The time interval is not specified.  Case  fatality  rate  is  typically  used  in  acute infectious diseases (e.g. , food  poisoning, cholera, measles). Its  usefulness  for chronic  diseases  is  limited,  beca...
4
1%
0.25%
5%
25%
Dental
null
4409e155-8167-415f-bda2-48d36bc91253
single
Activation of which of the following receptors would be expected to decrease anxiety?
Meissner and Pacinian corpuscles are examples of rapidly adapting receptors, and Merkel cells and Ruffini endings are examples of slowly adapting receptors. Ganong 23 rd ed, pg 153
3
nicotinic cholinergic receptors
glutamate receptors
GABA A receptors
glucocorticoid receptors
Physiology
null
a4efb757-ec7f-4f69-a51e-a4585a851d6a
single
All of the following reflexes are present at birth except:
Only landau and parachute reflexes are not present since birth.
3
Startle reflex
Moro's reflex
Landau reflex
Walking reflex
Dental
null
140d283e-b09c-4612-b39d-914297bf0e46
multi
The endotoxin of the following gram-negative bacteria does not play any part in the pathogenesis of the natural disease -
null
3
Escherichia coli
Klebseilla spp.
Vibrio cholerae
Pseudomonas aeruginosa
Medicine
null
cc704cc3-de23-4eb9-8397-2e58e11d68f9
single
Which of the following has least extra-pyramidal side effect?
Clozapine and risperidone are atypical neuroleptics with least extrapyramidal side effects among all an psychotics.
3
Haloperidol
Fluphenazine
Clozapine
Flupenthioxol
Pharmacology
All India exam
f8dba790-1ca1-44c1-b86d-e4c28af20aa3
single
James lind is known for -
Ans. is 'c' i.e., Prevention of scurvy by fruits Germ theory of disease --) Louis pasteur Spontaneous generation theory Aristotle Multifactorial causation of disease --) Pattenkoffer. o Intake of fresh (citrus) fruits in prevention of scurvy - James Lind o Term 'Vaccination Edward Jenner o Term 'Vaccine' --* Louis Past...
3
Germ theory of disease
Multifactorial causation of disease
Prevention of scurvy by fruits
null
Social & Preventive Medicine
null
435d623c-c796-4202-96a4-81018a883ed0
multi
Maximum interval between bare metal cardiac stent and elective surgery is
1 month is ideal interval between bare metal cardiac stent and any elective surgery.
3
1 year
2 month
1 month
2 year
Anaesthesia
null
c6f05ec6-13d1-40a4-a4f5-781cd36936ff
single
What is the clearance of a substance when its concentration in the plasma is 10mg/dl, its concentration in the urine is 100mg/dl and urine flow is 2ml/min?
The Clearance of a Substance &;X&; is equal to the concentration of substance X in urine (UX) times the urine flow per unit of time (V) divided by the aerial plasma level of X (PX), or UXV/PX.This value is called the clearance of X (CX).Coming to the above question: 100 mg/dl X 2 ml/min / 10 mg/dl = 20 ml/min.
3
0.2ml/min
2ml/min
20ml/min
200ml/min
Microbiology
All India exam
43d4c0b5-8909-4eb1-b0e9-cd0b728796ce
single
Botulism is a disease of: -
Neuromuscular transmission caused by the toxin of the bacterium Clostridium botulinum leads to botulism. C. botulinum produces powerful neurotoxin 'botulinum toxin'(BT). Botulinum toxin is absorbed from the gut, enters the blood circulation, and binds to receptors of presynaptic membranes of motor neurons of PNS and cr...
3
Neural transmission caused by the toxin of the bacterium Clostridium botulinum
Muscular transmission caused by the toxin of the bacterium Clostridium botulinum
Neuromuscular transmission caused by the toxin of the bacterium Clostridium botulinum
Non neuromuscular transmission caused by the toxin of the bacterium Clostridium botulinum
Microbiology
Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli)
db52b83d-d86b-471e-a8f8-0ffbec52f359
single
A 55 years old female presents with tinnitus, dizziness and h/o progressive deafness. Differential diagnosis includes all except:
Ans. is 'd' i.e. Histiocytosis X It is very well known that first 3 options i.e., Acoustic neuroma, endolymphatic hydrops (Miniers disease), and Meningioma can cause tinnitus and u/1 progressive deafness, (although Menier disease is usually b/l but initial presentation is u/l and the other ear is also involved in a few...
4
Acoustic neuroma
Endolymphatic hydrops
Meningioma
Histiocytosis-x
ENT
Ear
41f7e387-2a7e-4184-af1f-338ef8040320
multi
Superior cervical ganglion
Superior cervical ganglion is largest cervical ganglion. The plexus formed around internal carotid artery supplies dilator pupille. Superior cervical cardiac branch on left goes to superficial cardiac plexus,while that on right goes to deep cardiac plexus.
3
Is the smallest cervical ganglion
Gives rise to plexus around internal carotid artery, a part of which supplies sphincter pupillae
Deep petrosal nerve of pterygopalatine ganglion is derived from plexus around internal carotid artery
Left superior cervical cardiac branch goes to deep cardiac plexus
Anatomy
null
d7ae5b78-63af-4d7a-a0f0-dc5ab2b9154f
multi
All of the following anti-microbials show Concentration dependent Killing except
* Time dependent killing(TDK) : Here, the killing activity depends upon the length of time, plasma concentration is above MIC. It is shown by:* Beta Lactams.* Vancomycin* Concentration dependent killing(CDK) : Here, killing activity depends upon the ratio of plasma concentration to MIC.It is shown by:* Aminoglycosides....
3
Amikacin
Metronidazole
Penicillin G
Fluoroquinolones
Pharmacology
Cell Wall Synthesis Inhibitors
7ad1e7b7-7919-44ac-aa9c-7eb5e7e4e985
multi
Burst Fracture of spine is a -
Burst fracture (crushed communited fracture) is caused by axial (vertical) compression injury.
1
Compression Fracture
Extension injury
Direct injury
Flexion - rotation
Orthopaedics
null
416671ec-c917-4801-a231-ded58dffb89d
single
Normal cerebral blood flow is
Normal cerebral bloodflow (CBF) is about 55 mL per minute for every 100 gramsof brain tissue. Ischaemia results when this rate drops below20 mL per minute, and even lower levels will result in infarctionunless promptly corrected.Flow depends on cerebral perfusion pressure (CPP), the difference between mean aerial press...
2
45 ml/min for every 100gm of brain tissue
55 ml/min for every 100gm of brain tissue
65 ml/min for every 100gm of brain tissue
75 ml/min for every 100gm of brain tissue
Surgery
Trauma
7680d8b8-9f14-4bd0-9883-c1036624f01d
single
To assess which of the following, Look Listen Feel technique is used?
Adequate breathing ensures that sufficiently oxygenated blood is in circulation. Breathing is assessed by the Look-Listen feel technique. The clinician observes the rise and fall of the chest and at the same time feels and listens to the breath sounds. If the child is breathing adequately, then maintain the head tilt c...
2
Airway
Breathing
Circulation
Definitive therapy
Dental
null
f5136f8d-5b3f-444b-89be-8b78f234ef98
single
A 4-year-old presents with Labia lingual caries affecting only maxillary incisors and involving molars The diagnosis would be
null
2
Type I ECC
Type II ECC
Type III ECC
Rampant caries
Dental
null
9e7c3bb8-0075-4ea4-ae24-34fb9ced2586
single
Short bevel extends
Types of Bevel
3
In almost 2/3rd of enamel
Entire enamel + half dentin
All of enamel only
1/3rd of enamel
Dental
null
e00a8c4d-353a-40a6-aff4-1d14478bb0c1
multi
In a lateral cephalogram, the distance at which the film is placed from the mid-sagittal plane is:
null
3
10 cms
12 cms
15 cms
18 cms
Dental
null
92f2e0d4-b75f-4d38-8089-77015f019ee3
single
Which muscle has an indirect effect on the extent of impression in labial vestibule (maxilla)
null
1
Orbicularis oris
Buccinator
Masseter
Levator anguli oris
Dental
null
003b0ee9-5ffa-414b-a9a7-73ed1a6ad393
single
Histogram is used to describe -
Ans. is 'a' i.e., Quantitative data of group of patients
1
Quantitative data of a group of patients
Qualitative data of a group of patients
Data collected on nominal scale
Data collected on ordinal scale
Social & Preventive Medicine
null
68befdb8-1a33-4703-8abc-48c80d3d5981
single
Steroid induced cataract is
Steroid induced cataract occurs due to deposition of mucopolysacharides in the trabecular mesh work
1
Posterior subscapular
Anterior subscapular
Nuclear cataract
Cupulliform cataract
Ophthalmology
Lens
60a1010c-5e53-4997-a870-0549ce3f32ad
single
Streptomycin is a?
Ans. is 'b' i.e., Gycoside o Streptomycin is an amino-glycoside i.e. amino group is linked to aminosugar by glycoside bond.
2
Peptide
Gycoside
Phospholipid
Glycolipid
Pharmacology
null
ddf62ad1-c763-4a09-914a-21a231758479
single
Small bowel vascular ectasia is associated with:
Vascular Ectasias Vascular ectasias are flat mucosal vascular anomalies They are best diagnosed by endoscopy. They generally causes slow intestinal blood loss Classical example is: gastric antral vascular ectasia (GAVE) or "watermelon stomach" Other examples are: a) Cecal vascular ectasias (senile lesions) b) Radiation...
3
Retroviral infection
Amyloidosis
Chronic renal failure
Watermelon stomach
Medicine
null
a23ac09a-02b4-47f1-bc88-dcd3a1a65aca
multi
intermittent claudication is seen when ankle brachial index is ?
0.5-0.9 = intermittent claudication ref : bailey and love 27th ed
3
0.9-1
<0.3
0.5-0.9
>1.1
Surgery
All India exam
f4262773-c80b-4013-b79f-4b1b647735c5
single
On 3 phase 99m Tc - MDP bone scan, which of the following bone lesions will show least osteoblastic activity -
Osteoid osteoma, Paget's disease and fibrous dysplasia have osteoblastic activity, therefore, show increased radioisotope uptake on bone scan. Fibrous cortical defect shows no radioisotope uptake as it has no osteoblastic activity.
4
Paget' disease
Osteoid osteoma
Fibrous dysplasia
Fibrous cortical defect
Radiology
null
4db202ab-37c4-4ab6-bae1-fe4c6c1c280f
single
All are true about renal cell carcinoma, except ?
Ans. is 'd' i.e., More common in femalesRenal cell carcinoma (Adenocarcinoma of the kidney) o Also known as hypernephroma.o Renal cell carcinoma occurs usually in the sixth and seventh decades of life. o There is male preponderance in the ratio of 2 to 3 : 1.Risk factorsSmoking (most significant) o CRFo Obesity, hypeen...
4
Invades Renal Vein
Hematuria may occur
Arises from proximal convoluted tubule
More common in females
Pathology
null
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multi
Most common cause of chronic pancreatitis is:-
Most common cause of chronic pancreatitis is alcohol
1
Alcohol
Gall stones
Trauma
Smoking
Pathology
Miscellaneous
ee0a1860-f8dd-4dc4-928c-158d3c04a667
multi
All the following supply blood to Palatine tonsil except
Palatine Tonsil (The Tonsil)Blood supply:1.Main source: The Tonsillar branch of the facial aery.2.Additional sources: (a) Ascending palatine branch of facial aery; (b) Dorsal lingual branches of the lingual aery; (c) Ascending pharyngeal branch of the external carotid aery; and (d) The greater palatine branch of the ma...
4
Lingual aery
Facial aery
Ascending Pharyngeal aery
Sphenopalatine aery
Anatomy
Head and neck
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multi
All are examples of point mutation, except
A frameshift mutation is a genetic mutation caused by a deletion or inseion in a DNA sequence that shifts the way the sequence is read. A DNA sequence is a chain of many smaller molecules called nucleotides Ref-Harpers illustrated biochemistry 30/e p658
2
Silent mutation
Frame-shift mutation
Missense mutation
Nonsense mutation
Biochemistry
Metabolism of nucleic acids
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multi
Ramu is 60 year old male with CA Descending colon presents with acute intestinal obstruction. In emergency depament tit of choice is -
Ans is 'b' ie Haman's procedure As already explained above, a variety of operations can be done in the obstructing lesion of left colon depending on a variety of factors, but Haman's procedure is the most commonly preferred operation.
2
Defunctioning colostomy
Haman's procedure
Total colectomy
Lt hemicolectomy
Surgery
null
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Iron absorption is increased by the following factor in diet:
In a vegetarian diet, nonheme iron is absorbed very poorly because of the inhibitory action of a variety of dietary components, paicularly phosphates, phytates and high fibre content. Ascorbic acid and meat facilitate the absorption of nonheme iron. Ascorbate forms complexes with and/or reduces ferric to ferrous iron. ...
1
Vitamin-C
Phytic acid
Fibre diet
Phosphates
Physiology
null
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Which of the following is the best induction agent: September 2009
Ans. D: Thiopentone Thiopental is an ultra-sho-acting barbiturate and has been used commonly in the induction phase of general anaesthesia Following intravenous injection the drug rapidly reaches the brain and causes unconsciousness within 15 seconds. At one minute, the drug attains a peak concentration of about 60% of...
4
Ketamine
Diazepam
Nitrous oxide
Thiopentone
Anaesthesia
null
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single
In optic atrophy pallor of the optic disc is an index of
OPTIC ATROPHY It refers to degeneration of the optic nerve, which occurs as an end result of any pathologic process that damages axons in the anterior visual system, i.e. from retinal ganglion cells to the lateral geniculate body. Clinical features of optic atrophy : 1. Loss of vision, may be of sudden or gradual onset...
3
Atrophy of the nerve fibre
Gliosis
Loss of vasculature
All of the above
Ophthalmology
Neuro-ophthalmology
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What is the recommended schedule for pre exposure prophylaxis for rabies?
Persons who have a high risk of exposure to rabies such as staff working with rabies virus, veterinarians should be administered pre exposure prophylaxis against rabies. Such immunization consists of cell culture vaccine administered on days 0, 7 and 28. Ref: Park 21st edition, page 256.
3
0, 3, 7 days
0, 7, 14 days
0, 7, 28 days
0, 3, 7, 14, 21 days
Social & Preventive Medicine
null
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single
Third generation oral contraceptive pills containing norgestimate and gestodene along with estrogens:
null
1
Are more lipid friendly
Decreases the risk of venous thromboembolism
Increase the risk of breakthrough bleeding
Are not used for emergency contraception
Gynaecology & Obstetrics
null
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single
Cause of thick pancreatic secretions in cystic fibrosis?
CF occurs because of mutations in the gene that makes a protein called CFTR (cystic fibrosis transmembrane regulator). A person with CF produces abnormal CFTR protein -- or no CFTR protein at all, which causes the body to make thick, sticky mucus instead of the thin, watery kind. This blockage causes a drop in the amou...
3
Overproduction of mucin
Failure to clear mucin due to epithelial dysfunction
Defect in chloride channel leading to water reabsoption
Defect in sodium channel leading to water reabsorption
Medicine
Genetics
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multi
Dracunculosis infection occurs through -
Humans are the definitive host and cyclops are the intermediate host.The adult female worm discharges larvae which are ingested by the intermediate host the cyclops.Humans become infected by drinking unfiltered water containing infective cyclops (refer pgno:175 baveja 3 rd edition)
1
Ingestion of water containing cyclops
Ingestion of water containing the parasite
Ingestion of fish
Penetration of skin
Microbiology
parasitology
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single
To say twin discordance the difference in the two twin's weight should be:
Discordant twins: The donor twin should be > 20% smaller in weight than the recipient twin Abdominal circumference difference of >15%
3
15% with the larger twin as index
15% with the smaller twin as index
20% with the larger twin as index
25% with the smaller twin as index
Gynaecology & Obstetrics
Twin Pregnancy, Molar Pregnancy, Gestational Trophoblastic disease and contraception in special situations (Sour Grapes!)
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The biochemical role of vitamin K in the post translational modification of clotting factors is by :
null
2
Glycosylation
Carboxylation
Acetylation
Phosphorylation
Pharmacology
null
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single
All true about accidental intraerial injection of thiopentone except-
The accidental intraerial injection of drug by wrongly placed cannula M/N- 1 Leave the cannula 2 Intraerial injection of heparin 3 Lidocaine, papaverine, phenoxybenzamine injected 4 Stellate ganglion block
3
Immediate intense vasoconstriction and excruciating pain
Cause is precipitation of thiopental crystalls in the aerial vessels
To relieve pain we have to immediately remove the misplaced aerial cannula
Stellate ganglion block is one of the treatment modality
Anaesthesia
Intravenous Anesthetic Agents
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multi
The following drug acts by hypomethylation-
Ans. is 'c' i.e., Decitabine o Decitabine a cytidine analogue (pyrimidine analogue), causes hypomethylation by inhibiting DNA methyl transferase. o Other drug causing hypomethylation by inhibiting DNA methyl transferase - Azacitidine.
3
Gemcitabine
Capecitabine
Decitabine
Cytosine arabinoside
Pharmacology
null
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single
"Air crescent" sign is seen in
"Air crescent" sign is seen in fungal ball or aspergilloma in a tubercular cavity. Ref ganong's review of medical physiology 25e 765
2
Hydatid cyst
Aspergillosis
Tuberculosis cavity
Amoebic liver abscess
Physiology
All India exam
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Vital layer in slow sand filter is seen in -
Elements of slow sand filter: supernatant or raw water (1-1.5 metre) a bed of graded sand an under-drainage system a system of filter control valves The surface of the sand bed gets covered with a slimy growth known as "Schmutzdecke", vital layer, zoological or biological layer. The formation of the vital layer is call...
2
Top of water
On the sand bed
Near filter
null
Social & Preventive Medicine
Environment and health
1be223ac-1088-4fb5-a7da-6917a1976703
multi
Diamond finishing instruments use diamond particles of size:
Diamond particle size is commonly categorized as coarse (125 to 150 µm), medium (88 to 125 µm), fine (60 to 74 µm), and very fine (38 to 44 µm) for diamond preparation instruments.  Diamond finishing instruments use even finer diamonds (10 to 38 µm) to produce relatively smooth surfaces for final finishing with diamond...
2
60 to 74 µm
10 to 38 µm
38 to 44 µm
5 to 8 µm
Dental
null
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single
Preconception counseling for a woman is given by:
Ans. d. All
4
Obstetricians
Midwives
General physician
All
Social & Preventive Medicine
Demography and Family Planning
1bec4241-324c-48b4-b244-d2b389c25b0f
multi
A 2 month old infant presented with hepatic crisis, peripheral neuropathy & fanconi like syndrome. Lab investigations showed elevated transaminase, low coagulation factors and elevated succinyl acetone in serum & urine. The most likely diagnosis :
Tyrosine is derived from ingested proteins or is synthesized endogenously from phenylalanine. It is used for protein synthesis and is a precursor of dopamine, norepinephrine, epinephrine, melanin, and thyroxine. Tyrosinemia type I or Hereditary tyrosinemia or Hepatorenal tyrosinemia Caused by a deficiency of the enzyme...
3
Phenyl ketonuria
Homocystinuria
Tyrosinemia
Hawkinsinuria
Pediatrics
Disorders of Amino acid Metabolism
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single
A child presented at 10 weeks with recurrent episode of pneumonia and failure to thrive. X-ray show cardiomegaly & pulmonary plethora diagnosis?
- Features given in the question are suggestive of VSD VENTRICULAR SEPTAL DEFECT : - Communication b/w 2 ventricles of hea - 90% are located in membranous pa of ventricular septum with variable extension into muscular septum. - Clinical features: Usually presents at 6-10 weeks of age Recurrent episodes of pneumonia Hea...
1
VSD
ASD
TOF
Patent foramen ovale
Pediatrics
Acyanotic congenital hea diseases
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single
Permissible level of fluoride in drinking water as per WHO is:
As per WHO, permissible limit of fluoride in drinking water is 1.5 mg/ litre. As per Bureau of Indian Standards (BIS), it is 1 mg/ litre. Dental fluorosis has been repoed with exposure to levels > 1.5 mg/ litre. Skeletal fluorosis has been repoed on exposure between 3 to 6 mg/ litre. Ref: Park, 21st Edition, Page 668
3
0.5 mg/litre
1.0 mg/litre
1.5 mg/litre
2.5 mg/litre
Social & Preventive Medicine
null
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single
Fusion of two eyelids by thin tags is called
Answer- A. Ankyloblepharon filiforme adnatumIn ankyloblepharon filiforme adnatum the upper and lower eyelids are joined by thrn tags; most cases are sporadic. Treatment involves transection with scissors.
1
Ankyloblepharon filiforme adnatum
Euryblepharon
Ablepharon
Epiblepharon
Ophthalmology
null
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multi
Righting reflex is a -
Ans. Is "c" i.e., Vestibular reflex Vestibular reflexeso The information collected by vestibular apparatus leads mainly to reflex adjustment in posture and eye movements,o Both these functions are also affected by information from other sensory structures.o In intact organism the regulation of posture and of the eye mo...
3
Cochlear reflex
Spinal reflex
Vestibular reflex
None of the above
Physiology
Nervous System
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multi
Temporal lobe tumours may produce
Ans. Crossed upper quadrantanopia
1
Crossed upper quadrantanopia
Crossed lower quadrantanopia
Uncrossed upper quadrantanopia
Uncrossed lower quadrantanopia
Ophthalmology
null
13e08522-74d5-4ab3-ad78-e484e5789f50
single
A patient is on low calcium diet for 8 weeks. Level of which of the following increases to maintain serum calcium levels?
The primary function of PTH is to maintain the extracellular fluid (ECF) calcium concentration within a narrow normal range. The hormone acts directly on bone and kidney and indirectly on the intestine through its effects on synthesis of 1,25(OH)2D to increase serum calcium concentrations; in turn, PTH production is cl...
1
PTH
Calcitonin
Active 24, 25 dihydroxy cholecalciferol
Serum phosphate level
Physiology
null
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single
Touton Giant cells are seen in -
Ans. is 'c' i.e., Xanthoma Tauton giant cells These cells have a ring of nuclei that separates a peripheral clear cytoplasm from an eosinophilic central cytoplasm. These cells are seen in juvenile xanthogranuloma in skin or iris and in Xanthoma disseminatum.
3
Cat scatch disease
Sarcoidosis
Xanthomas
Neurofibroma
Pathology
null
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single
Hu includes all except -
the synopsis of forensic medicine & toxicology;Dr k.s narayan reddy; 28th edition; pg.no. 154 . Hu means bodily pain,disease or infirmity caused to any person .
2
Physical pain
Mental pain
Infirmity
Disease
Forensic Medicine
Mechanical injuries
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multi
Most common adverse effect of oral contraceptive is:
Ans. Opticneuritis
2
Colour blindness
Optic neuritis
Ringscotoma
Nystagmus
Ophthalmology
null
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single
Which of the following toxin causes lathyrism?
Ans. d (BOAA). (Ref. Park, Textbook of PSM, 17th ed., 441)LATHYRISM# Neurolathyrism is crippling disease of nervous system characterised by gradually developing spastic paralysis of lower limbs, occuring in adults consuming the pulse, Lathyrus sativus ("khesari dhal").# The toxin present in lathyrus is beta oxaly amino...
4
Berberine
Pyrazolidone
Sanguinarine
BOAA
Social & Preventive Medicine
Nutrition and Health
6ac07ba8-156b-4a89-a017-87409acf6850
single
A middle aged lady was diagnosed to incidentally have a ejection systolic murmur at the pulmonary area. A fixed wide split of the second heart sound was also noted. The diagnosis is:-
Classically presents as an asymptomatic patient with a flow murmur in the pulmonary area and a fixed  wide split of S2. Atrial septal defects occur most commonly in the region of the fossa ovalis, referred to as secundum-type defects .Additional atrial  septal  defects  include  defects  of  the  sinus  venosus  and  atr...
2
Tetralogy of Fallot
Atrial septal defect
Mitral stenosis
Mitral valve prolapse
Medicine
null
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multi
Which of the following diuretic should not be given along with aminoglycosides?
Flurosemide is a loop diuretic which can lead to ototoxicity and hence contraindicated along with aminoglycosides.
2
Chlorthiazide
Flurosemide
Dorzolamide
Canrenone
Pharmacology
null
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multi
This condition is caused by:
Ans. (a) Paralytic Ileus.Image shows presence of multiple air fluid levels suggestive of paralytic ileus. Causes are--1. Postoperative2. Infection - typhoid3. Reflex - following fractures of spine or retroperitoneal hemorrhage4. Uremia - following prostatectomy5. Hypokalemia Image source- style="font-family: Times New ...
1
Paralytic Ileus
Hyperkalemia
Acute intestinal obstruction
Malnutrition
Surgery
Small Intestine - Small Bowel Obstruction
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single
Which amongst the following a marker of carinoma-
Cytokeratins are a class of intermediate filaments that demonstrates epethelial differentiation and are the most commonly used marker to identify 'Carcinomas'.
1
Cytokeratin
Vimentin
Calretinin
CD45
Pathology
null
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single
Commonest cause of carcinoma endometrium is
(Unopposed estrogen) (392-S) (374-SI4th)Predisposing factors for carcinoma endometrium* Unsupervised administration of HRT with oestrogens alone during the menopause predisposes these women to develop endometrial hyperplasia and cancer* Women with oestrogen dominance suffering from endometrial hyperplasia and presentin...
1
Unopposed estrogen
Multiple sex partner
Early marriage
Early menarchae
Gynaecology & Obstetrics
Miscellaneous (Gynae)
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single
Acromegaly results due to excessive release of:
Ans. B. Growth hormoneIn Acromegaly there is excessive release of Growth Hormone. It occurs after the epiphyseal closure and is characterized by increase in the size of hands, facial changes, excessive hair, thickening of skin etc.
2
Thyroxine
Growth hormone
Insulin
Glucagon
Biochemistry
Endocrinology
f2d7fd4c-7fce-453e-9cb5-8ada2755fd0b
single
Which is NOT seen in urine in obstructive jaundice?
Normally, there are mere traces of urobilinogen in the urine. In complete obstruction of the bile duct, no urobilinogen is found in the urine, since bilirubin has no access to the intestine, where it can be conveed to urobilinogen. In this case, the presence of bilirubin (conjugated) in the urine without urobilinogen s...
1
Urobilinogen
Direct bilirubin
Both of the above
None of the above
Biochemistry
null
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multi
Over the past several weeks, a 2-year-old girl has exhibited developmental regression, abnormal sleep patterns, anorexia, irritability, and decreased activity. These symptoms have progressed to acute encephalopathy with vomiting, ataxia, and variable consciousness. The family recently moved, and they are in the process...
The most important aspect of the management of lead poisoning is the identification and withdrawal of the source of the lead. Patients with symptomatic lead poisoning or extremely high lead levels in the blood (> 70 mg/dL) should be treated with both dimercaprol and calcium EDTA. With milder poisoning, intravenous or i...
3
Atropine and pralidoxime (2-PAM)
N- acetylcysteine (Mucomyst)
Dimercaptosuccinic acid (DMSA, succimer)
Naloxone (Narcan)
Pediatrics
Growth, Development, and Behavior
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multi
Dye used in fluorescent microscopy -
Ans. is `D' i.e., Auramine
4
Thioflavin T
Congo red
Brilliant blue
Auramine
Microbiology
null
4c6a55f4-ba36-4fb5-9dde-6860d49f9efd
single
A 25-year-old machinist is injured by a metal sliver in his left hand. Over the next few days, the wounded area becomes reddened, tender, swollen and feels warm to the touch. Redness at the site of injury in this patient is caused primarily by which of the following mechanisms?
Vasodilation of precapillary aerioles increases blood flow at the site of tissue injury. This condition (active hyperemia) is caused by the release of specific mediators. Vasodilation and hyperemia are primarily responsible for the redness and warmth (rubor and calor) at sites of injury. The other choices do not regula...
4
Hemorrhage
Hemostasis
Neutrophil margination
Vasodilation
Pathology
Basic Concepts and Vascular changes of Acute Inflammation
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single