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Ergot alkaloids are used in all except -
Ans. is 'c' i.e., Hypertension Uses of ergot alkaloids1. Migraineo In migraine, throbbing headache is due to dilatation of pain sensitive arteries outside the brain, i.e. extracerebral vessels.o Ergot alkaloids are vasoconstrictor (due to a agonistic action) and oppose these effects,o Ergot alkaloids used in migraine -...
3
Migraine
Acromegaly
Hypertension
Parkinsonism
Pharmacology
C.N.S
b187cde0-0d31-42ea-a84d-6b4109c0aa8f
multi
HLA B27 is positive in
Ref Robbins 8/e p193; Harrison 17/e p2051 ;9/e p215 The HLA complex, which is located on the sho arm of human chromosome 6, contains sequences encoding about 100 genes, most involved in the regulation of the immune response. HLA genes are classically grouped into three major classes.
1
Ankylosing spondylitis
Rheumatoid ahritis
SLE
Behcet syndrome
Anatomy
General anatomy
36b1e3a9-5596-4992-8729-3b39ac3fd97b
single
In RMNCH+A Startegy, what is plus -
Ans. is 'a' i.e., Adolescent health o The RMNCH+A strategy is based on provision of comprehensive care through the five pillars, or thematic areas, of reproductive, maternal, neonatal, child, and adolescent health, and is guided by central tenets of equity, universal care, entitlement, and accountability. The "plus" wi...
1
Adolescent health
Reproductive health
DPT Vaccination
Newborn health
Social & Preventive Medicine
Health Programmes in India
80688b75-8dca-4679-a39d-9545c44e9b34
single
What is deposited in Kyser-FIeischer ring -
Ans. is 'a' i.e., CopperKayser-FLeischer (KF) ring - Copper deposition in Chalcosis or Wilson's diseaseFleischer ring - Deposition of iron and is a sign of keratoconus
1
Copper
Lead
Mercury
Heme
Ophthalmology
Cornea
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single
Psammoma body found in -
Ans is 'a' i.e. Papillary Ca Psammoma bodies found in: Ref. Papillary Ca of thyroid 8/e p1122 (7/e p1178) Serous cystadenoma of ovary 8/e 1044 (7/e p1096) Meningioma 8/e p1338 (7/e p1409) Papillary type of Renal cell carcinoma 8/e p966 (7/e p1018) Pitutary adenoma (Prolactinoma) 8/e p1103 (7e p1160) Appendiceal carcino...
1
Papillary Ca thyroid
Follicular Ca thyroid
Medullary Ca thyroid
Anaplastic Ca thyroid
Surgery
null
ee2e513a-9600-4ccf-a21b-5fc53c244ceb
single
In this poisoning, the vomitus is:
GIT symptoms with boric acid can mimics acute gastroentritis. Nausea, vomiting (bluish green), haematemesis, diarrhoea (bluish green)
1
Bluish green
Black
Brown
Red velvetty
Forensic Medicine
Toxicology - 1
67f9b675-df37-4997-85cb-e5c0b65d205d
single
High or low fistula is ano is termed according to its internal opening present with reference to
The anorectal ring marks the junction between the rectum and the anal canal. It is formed by the joining of the puborectalis muscle. the deep external sphincter, conjoined longitudinal muscle and the highest pa of the internal sphincter. The anorectal ring can be clearly felt digitally, especially on its posterior and ...
3
Anal canal
Dentate line
Anorectal ring
Sacral promontary
Surgery
G.I.T
22d07568-d0cc-4d7d-976a-03421c1eb49d
single
Wobble hypothesis -regarding the variation true is:
B i.e., 5-end of anticodon
2
3 - end of anticodon
5 - end of anticodon
m-RNA
t-RNA
Biochemistry
null
d389e0b7-7190-496d-8d35-e51fad76aab8
multi
isolated conjugated hyperbilirubinemia is seen in the following conditions except-
Gilbe's syndrome is by far the most common inherited disorder of bilirubin metabolism . It is an autosomal recessive trait when caused by a mutation in the promoter region of the gene for UDP-glucuronyl transferase enzyme (UGT1A1), which leads to reduced enzyme expression. It can be inherited in a dominant fashion when...
2
Hemolysis
Gilbe syndrome
Crigler-Najjar syndrome
Dubin-Johnson syndrome
Medicine
G.I.T
72cda82b-2bdc-4846-accb-b13ded41d111
multi
True about inverted papilloma is -
Ans. is 'a' i.e., It is also known as Schnedrian papilloma "Inverted papilloma of nose" -o It is also called Schneiderian papilloma, squamous papilloma or papillomatosiso It is a polypoid mass occuring on the lateral nasal wall typically in middle aged men.o The name is derived from its histologic appearance of on inve...
1
It is also known as Schnedrian papilloma
Anatomically It has an inverted appearance
It may cause basal cell carcinoma
It is commonly seen in young girls
Surgery
E.N.T.
382994cb-2ec5-4441-8859-0472bc8c538d
multi
Treatment of rectal prolapse in childhood is -
• Prolapse during childhood is best managed conservatively, the only exception is persistence of prolapse despite effective treatment of diarrhea, worm infestation and malabsorption. These cases are managed by surgery.
3
Lahaut's operation
Incision of prolapsed mucosa
Thiersch wiring
Ripstein operation
Surgery
null
01835b22-2e3d-4e80-a64d-26f5c29bc227
single
All are true about subacute combined degeneration of spinal cord except -
null
4
Due to deficiency of vitamin B12
Posterior column involvement
Corrticospinal involvement
Absent deep tendon reflexes
Medicine
null
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multi
The most common and the most poorly tolerated heart disease during pregnancy is:
Ans. c (Aortic stenosis). (Ref. Dutta, Obstetrics, 6th ed., p 281)# Aortic stenosis has maternal mortality of 15-20% and Perinatal loss of 30%.HEART DISEASE IN PREGNANCY# The risk of fetal congenital malformations is increased by 3-10% if either parents have congenital lesions.# In mother with ASD, risk of having conco...
3
Mitral stenosis
Mitral regurgitation
Aortic stenosis
Aortic regurgitation
Gynaecology & Obstetrics
Miscellaneous (Gynae)
99de6a97-2596-494d-9422-2a19d28b7ab3
single
Which of the following is true of small bowel carcinoids
Ans. is 'none' Lets see each option one by one Most common site: Most common site for small bowel carcinoids is ileum. About 70-87% are present within the ileum and 40-70% are within 2 ft of the ileocecal valve. Among all carcinoids most common site is GI tract 2nd most common site is respiratory tract Endocardial fibr...
4
Most common site is duodenum
It does not cause endocardial fibroelastosis
Increased risk of Ca lung
null
Surgery
null
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The obstruction of two or more major hepatic veins is seen in
Budd-Chiari syndrome It is caused by obstruction of hepatic venous outflow producing intense congestion of the liver Etiology Polycythemia rubra Vera is the most common etiology In the West, thrombosis of the major hepatic veins is more common In BCS all three major hepatic veins usually are occluded Small hepatic vein...
1
Budd-Chiari syndrome
Reye's syndrome
Rotor syndrome
Crigler-Najjar syndrome
Anatomy
G.I.T
0e875125-369d-4715-a798-2b80280533a6
single
Sympathectomy is indicated in
null
4
Buerger’s disease
Atherosclerosis producing ischemia of limbs
Raynaud’s disease
All of the above
Surgery
null
f2beed25-278e-493b-8d39-a93fd47ad74d
multi
A man presents with chest pain. ECG shows ST-segment depression in leads V1-V4. Which of the following should not be given?
Thrombolytics like streptokinase, alteplase, reteplase are beneficial to patients with ST-elevated MI Max. benefit will be seen if they were given with 6 hours of the onset of MI Their use in ST depressed MI is contraindicated
2
Beta blocker
Thrombolytic
Morphine
Aspirin
Pharmacology
Cardiovascular system
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single
The antihypeensive agent that should be avoided in young females and is used topically to treat alopecia is:
Minoxidil is a powerful vasodilator Active metabolite of minoxidil is an opener of ATP sensitive K channels; causes vasodilatation by hyperpolarizing smooth muscle. Minoxidil is avoided in young females because it causes Hirsutism. Drugs causing Hirsutism: Phenytoin Cyclosporine Minoxidil USE OF MINOXIDIL IN ALOPECIA -...
3
Hydralazine
Prazosin
Minoxidil
Indapamide
Pharmacology
Hypeension, Arrhythmias, Dyslipidemia
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Shoest acting non depolarizing muscle relaxant is
Suxamethonium (succinylcholine) is the shoest acting skeletal muscle relaxantMivacurium is the shoest acting nondepolarizing skeletal muscle relaxant.(Refer: stoelting's pharmacology and physiology in anaesthetic practice, 5th edition, pg no.139)
1
Mivacurium
Doxacuronium
Pipecurium
Vecuronium
Anaesthesia
All India exam
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single
Active immunity is not acquired by:(1994)
Ans: c (Immunoglobulin transfer)Ref: Ananthanarayan Micro, 7lhed, p. 76 & 6th ed, p. 73
3
Infection
Vaccination
Immunoglobulin transfer
Sub clinical infection
Microbiology
Immunology
474c551b-2a04-490f-8e91-7d99918e4142
single
An HIV patient complains of visual disturbances. Fundal examination shows bilateral retinal exudates and perivascular haemorrhages. Which of the following viruses are most likely to be responsible for this retinitis-
This is a typical feature of Cytomegalovirus (CMV) retinitis. Pizza pie appearance of fundus in CMV retinitis.(In HIV +ve patient, if CD4+ count is <50 cells/ microlitre) Herpes simplex- type 1 : conjuctivitis and corneal ulceration. Varicella zoster-corneal ulcer and zoster opthalmicus. EBV- not associated with retini...
3
Herpes simplex
Varicella zoster
Cytomegalovirus
EBV
Microbiology
Virology (General Propeies, DNA Viruses)
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single
Most common cause of gangrene of foot of 30-years old farmer who is a chronic smoker
null
4
Raynaud’s disease
Myocardial infarction
Atherosclerosis
Thromboangitis obliterans
Surgery
null
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single
Fogo selvagem is a type of:
Endemic pemphigus foliaceus common in rural pas of South America, paicularly ceain states of Brazil is known as fogo selvagem (wild fire) caused by bite of black fly. Ref: Rook's textbook of dermatology, 8th edition, Pg 40.13
3
Pemphigus vulgaris
Pemghigus vegetans
Pemphigus foliaceus
Bullous pemphigoid
Skin
null
d27dbf35-76e9-40bc-8fdf-9222c625f1d0
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All are aromatic amino acids EXCEPT:
(Lysine): Ref 49, U.S. (75- R.S. 7th)* Aromatic amino acids: Phenylalanine, tyrosine and tryptophan (with indole ring) are aromatic amino acids, Basides these histidine may also be considered this category.* Hydroxyl group containing amino acids: - Serine, Threonine, Tyrosine* Amino acids with aliphatic side chains: - ...
4
Phenylalanine
Tyrosine
Tryphophan
Lysine
Biochemistry
Proteins and Amino Acids
f7986f8a-eac8-4cc2-b90f-2de79c6bcd03
multi
The peak of fast EPSP or, fast IPSP is seen at what time after stimulus application:
Fast EPSP and fast IPSP begins 0.5 ms after the stimulus (known as latency). They peak 1-1.5 ms after the stimulus then decreases exponentially. Fast EPSP is due to influx of Na+ and or Ca++ in post synaptic neuron. Fast IPSP is due to influx of Cl- in post synaptic neuron.
2
0.5 ms
0.5 to 1.5 ms
11.5 ms
100-500 ms
Physiology
Introduction to Central Nervous System
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single
Popcorn cells are seen in:
Hodgkin lymphoma is currently classified in the following manner: Nodular lymphocyte-predominant Hodgkin lymphoma. Classical Hodgkin lymphoma (comprising five histopathologic subtypes): Lymphocyte rich Nodular sclerosis Mixed cellularity Lymphocyte depletion Unclassifiable These names describe the most prominent hi...
1
Hodgkin’s lymphoma
Non-Hodgkin's lymphoma
Burkitt’s lymphoma
Multiple myeloma
Pathology
null
bb474165-d1bf-4450-8a52-5c97bbfc4f9d
single
Micro RNA is -
Ans. is 'c' i.e., Gene Silencing RNA o There is a class of genes that encode for gene-silencing RNAs, i.e. RNAs that do not encode proteins but instead inhibit gene expression (unlike mRNAs) which encode for proteinso Two important gene-silencing RNAs are :- (i) Micro RNAs, and (ii) small interfering RNAs (siRNAs). i) ...
3
Splicing RNA
Snurps
Gene Silencing RNA
Ribonuclease
Biochemistry
Molecular Genetics
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single
Concurrent list does not encompass:
The regulation and development of medical profession is not included in the concurrent list and instead is placed in the Union list and is controlled by the union health ministry. Ref: Park Textbook of Preventive and Social Medicine, 19th Edition, Page 730
3
Prevention of extension of communicable disease from one unit to another
Prevention of adulteration of food stuffs
Regulation and development of medical profession
Vital statistics
Social & Preventive Medicine
null
71a970cf-92e3-4353-9f43-497456e6ca80
single
Which of the following in halational agent sensitizes myocardium to catecholamine -
Ans. is 'd' i.e., Halothaneo Some inhalational agent sensitize the heart to adrenaline -->>Arrhythmias can occur Therefore these agents are contraindicated in Pheochromocytoma and along with adrenaline.o Halothane has maximum propensity .o Other agents sensitizing the heart to adrenaline are Trilene, Cyclopropane, Chlo...
4
Sevoflurane
Isoflurane
Ether
Halothane
Anaesthesia
Miscellaneous General Anesthesia
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single
First response to decreased blood volume
Baroreceptor reflex is an immediate compensatory mechanism in shock. There is stimulation of aerial baroreceptors and so sympathetic output is increased leading to vasoconstriction and reflex tachycardia. Ref: Textbook of medical physiology by N Geetha, 2nd edition, page no. 184
1
Increased hea rate
Tachypnea
Hypotension
Disorientation
Physiology
Cardiovascular system
08231981-c129-4875-ac62-524833dca847
single
All are glands of eyelids EXCEPT:
Ans. (b) Lacrimal glandRef: A.K. Khurana 6th ed. / 386GLANDS OF EYELIDS* Meibomian glands: Also known as tarsal glands present in the stroma of tarsal plate and are arranged vertically.# They are modified sebaceous glands. Their ducts open at the lid margin. Their secretion constitutes the oily layer of tear film.* Gla...
2
Glands of zeis
Lacrimal gland
Meibomian gland
Glands of moll
Ophthalmology
Anatomy
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multi
Crowding phenomenon is seen in:
Crowding Phenomenon - patient is able to identify a Snellen chant character with the amblyopic eye when The character is presented in isolation. Crowding phenomenon seen in Amblyopia. Amblyopia - loss of vision in a child (<8yr) Lazy eye syndrome M/c/c of amblyopia = squint Best treatment of Amblyopia - occlusion of go...
2
Hypermetropia
Amblyopia
Strabismus
Retinitis pigmentosa
Ophthalmology
Optics and Errors of Refraction
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Dull appearance of mouth temperature wax indicates
null
4
Insufficient material
Overextension
Contact of the material with tissues
Partial contact of tissues
Dental
null
3a63cae5-8a20-42b4-a58f-e3e68860d9f4
single
All true about cephalosporins EXCEPT:
This 2nd generation cephalosporin was developed subsequent to the first generation compounds and are more active against gram-negative organisms, anaerobes, but none inhibits P. aeruginosa ESSENTISLS OF MEDICAL PHARMACOLOGY
3
Ceftazimide is a 3rd generation cephalosporin
Cefoperzone has got antipseudomonal effect.
Cefoxitin has got no activity against anaerobes
Cephalosporins act by inhibiting cell wall synthesis
Pharmacology
Chemotherapy
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multi
Which of the following is false about tympanic membrane:
(c) Healed perforation has 3 layers(Ref. Scott Brown, 8th ed., Vol 2; 529)The TM membrane which heals by itself does not have the fibrous layer. It has 2 layers only, the outer epithelial and the inner endothelial.Rest are true
3
Cone of light is antero-inferior
Shrapnell's membrane is also known as pars flaccida
Healed perforation has 3 layers
TM attachment to tip of malleus handle is called umbo
ENT
Ear
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multi
Not true of Gall stones
Ans. (d) Ileal resection has no effect on gall stone formationRef: Sabiston 20th edition Page 1492 Gall stones:* Cholesterol stones are common in Ileal resection and in cases of Crohn's disease due to decreased Entero hepatic circulation and decreased Bile salts.
4
Biliary fistula is a complication gall stone
More common in female
Clofibrate therapy is a predisposing factor
Ileal resection has no effect on gall stone formation
Surgery
Gall Bladder & Bile Ducts
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multi
All of them are true about the 4th nerve EXCEPT
The trochlear nerve has several features that make it unique from the other cranial nerves: Thinnest cranial nerve. Is the only nerve to exit from the dorsal surface of the brain. Is the only nerve in which all the lower motor neuron fibers decussate. Has the longest intracranial course. Has the smallest number of axon...
3
The only nerve to emerge from the dorsal aspect of brain
The only nerve to cross over to opposite side
It is the thickest cranial nerve
It has the fewest axons of any cranial nerve
Ophthalmology
Neuro Ophthalmology
77843896-46a6-4353-aa9a-5eb5fd504dbc
multi
Which of the following liners when exposed to oral fluids result in diminishment of their antimicrobial effectiveness?
MTA and calcium hydroxide undergo a transformation of hydroxide to calcium carbonate from exposure to carbon dioxide in the blood and oral fluids, causing their antimicrobial effectiveness to diminish.
3
MTA
Calcium hydroxide
Both
null
Dental
null
f53fc939-e389-47b1-bf08-e6a916e1ec8a
multi
Which of the following is the largest protein in the body that connects M line to Z line during active muscle contraction?
Ans. C. Titin. (Ref. Guyton & Hall's Textbook of Medical Physiology 11th/pg. 463)SarcomereThe portion of the myofibril (or of the whole muscle fiber) that lies between two successive Z discs is called a sarcomere. When the muscle fiber is contracted, the length of the sarcomere is about 2 micrometers. At this length, t...
3
Actin
Desmin
Titin
All of above
Physiology
General
67bb78da-3e2b-4c2d-9f85-e09d48462f1f
multi
A 35-year old lady presented with dysphagia>> nocturnal asthma and weight loss for 6 years. The most probable diagnosis is -
<P>Davidson&;s principles and practice of medicine 22nd edition #Achalasia cardia is presented with dysphagia ,episodic chest pain due to oesophageal spasm,nocturnal pulmonary aspiration, weight loss.</p>
1
Achalasia cardia
Lye stricture of esophagus
Gastroesophageal reflux diseae
Cancer esophagus
Medicine
G.I.T
a0a7ac1a-be54-48dd-9d35-aa53f7c58d5d
single
Radical neck dissection involves all except
Vagus nerve is not removed in Radical Neck Dissection. Structures removed in Radical Neck Dissection: Level I-V Lymph nodes, Sternocleidomastoid, Internal Jugular Vein, Spinal Accessory Nerve, Submandibular salivary gland, Tail of parotid and Omohyoid muscle. Ref: Textbook of ENT, Dhingra; 6th edition; Pg no: 388 ref i...
3
Sternocleidomastoid muscle
Internal jugular vein
Vagus nerve
Spinal accessory nerve
ENT
Miscellaneous ENT
9f817221-e452-4e07-8c68-b3da0d963908
multi
Which type of amyloidosis is caused by mutation of the transthyretin protein?
Familial amyloid polyneuropathy (FAP) is phenotypically and genetically heterogeneous and is caused by mutations in the genes for transthyretin (TTR), apolipoprotein A1, or gelsolin. The majority of patients with FAP have mutations in the TTR gene. Amyloid deposition may be evident in abdominal fat pad, rectal, or nerv...
2
Familial Mediterranean fever
Familial amyloidotic polyneuropathy
Dialysis associated amyloidosis
Prion protein associated amyloidosis
Pathology
null
eef1a8ed-b3be-4f9c-add6-d41157d2a092
single
Most common cause of precipitation of renal failure in multiple myeloma is
(C) Hypercalcaemia # Renal failure is seen in 25% patients and hypercalcaemia is the most common cause of renal failure.> Quite often renal failure develops rapidly even at an unchanged ratio of production and serum concentration of light chains. Various factors can favour renal cast formation in myeloma patients. Dehy...
3
Hyperurecemia
Infection
Hypercalcaemia
Amyloidosis
Medicine
Miscellaneous
75fc64f0-d253-4ae4-aec7-2c4d2f70a444
single
Presence of 1 up quark + 2 down quarks suggests the following:
null
2
Proton
Neutron
Electron
Positron
Radiology
null
451ab750-6028-441f-ac30-503e81a28784
single
Use of dexemditomidine ?
Ans. is 'b' i.e., Sedative agent for intubated patients Dexmeditomidine It is a centrally acting a-2 adrenergic agonist It is approved by F.D.A. for sho term (<24 hours) continuous IV sedation of adults who are tracheally intubated. Its use as an anaesthetic agent is not recommended but it is useful in patients with br...
2
Prolong action of LA in hypeensive patients
Sedative agent for intubated patients
Increases bioavailability of regional anaesthetic drug
Helps in reducing bispectral index of general anaesthetic drug with low potency
Anaesthesia
null
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single
What is Kienboch's disease
Ans. is 'a' i.e osteochondritis of lunate [Ref. : Maheshwari 3/e p269 (2/e, p268)JOsteochondritis :These are a group of miscellaneous affections of the growing epiphysis in children and adolescents.Typically, a bony nucleus of the epiphysis affected by osteochondritis becomes temporarily softened; and while in the soft...
1
Osteochondritis of lunate
Osteochondritis of neck of femur
Osteochondritis of navicular
Osteochondritis of tibial condyle
Orthopaedics
Bone
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single
Molar concentration of oral rehydration fluid is -
Ans. is 'b' i.e., Potassium 20 meq
2
Sodium 30 meq
Potassium 20 meq
Bicarbonate 30 meq
Chloride 20 meq
Pediatrics
null
6a9c12aa-1156-4bbe-8393-bb26b3d40ba0
single
Chronic thiazide therapy causes persistent hypercalcemia due to :
Ans. is 'd' Hyperparathyroidism Chronic thiazide therapy causes hypercalcemia because it enhances the parathyroid mediated increase of Ca reabsorption.Note: Thiazide diuretics cause hypercalcemia where as high ceiling diuretics cause hypocalcemia.Other important side effects of Thiazide diureticsHyperuricemia *Hypokale...
4
Renal tubular acidosis
Fanconi's syndrome
Hyper vitaminosis D
Hyper parathyroidism
Pharmacology
Diuretic
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single
Methemoglobinemia is a complication following the administration of
null
3
Lignocaine
Lignocaine
Prilocaine
Procaine
Pharmacology
null
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single
Cell of origin of hairy cell leukemia is -
Hairy cell leukaemia is an unusual & uncommon form of B cell malignancy characterized by presence of hairy cells in the blood & bone marrow & splenomegaly.Hairy cells are abnormal mononuclear cells with hairy cytoplasmic projections which are seen in blood,bone marrow & spleen.These cells exhibit CD19,CD20 & CD22 antig...
1
B-cell
T-cell
NK-cell
Dendritic reticulum cell
Medicine
Haematology
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single
Precautions advised after outpatient Radioiodine (I-131) therapy are all, EXCEPT:
There is no such contraindication as do not use household chlorine bleaches for cleaning. Children and Pregnant Women: If there are pregnant women, infants, and children under 16 years of age in the home, arrangements should ensure that a distance >6 feet (or 2 meter) can be maintained between the patient and these occ...
3
Carry treatment ceificate for 90 days
To stay 2 meters away from children and pregnant women
Do not use household chlorine bleaches for cleaning
Use contraception for three months
Radiology
null
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multi
Patients with Antiphospholipid antibodies may manifest with any of the following, except:
Answer is D (Thrombocytosis): Refer Review Notes on Antiphospholipid Syndrome Antiphospholipid Antibody Syndrome is associated with thrombocytopenia and not thrombocytosis. The presence of thrombocytopenia does not appear to reduce thrombotic risk in patients with APS. Recurrent aerial or venous thrombosis in any tissu...
4
Venous thrombosis
Aerial Thrombosis
Hemolytic Anemia
Thrombocytosis
Medicine
null
cf6e51c0-56b0-43bd-bb8b-cbe81c23e7a0
multi
Which irrigating solution has tissue dissolving properties
null
2
EDTA
Sodium Hypochlorite
Saline
Citric Acid
Dental
null
36b0eb58-51f6-4841-bcfb-f90941092730
single
Which of the following enzymes is used in Recombinant DNA research for Homopolymer tailing
Terminaldeoxynucleotidyltransferase catalyzes the addition of deoxynucleotides to the 3' termini of DNA. ... By use of a tailing method, which adds homopolymerdeoxynucleotide tails to denatured DNA, any double-stranded DNA fragment can be joined to a cloning vehicle Ref biochemistry satyanarayana 4e p255
4
Reverse transcriptase
S1 Transferase
Polynucleotide kinase
Terminal transferase
Biochemistry
Structure and function of protein
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single
Hardness number which does not depend on the ductility of metal:
KNOOP HARDNESS TEST (KHN) A diamond indenting tool is used. Knoop hardness values is independent of the ductility of the material and values for both exceedingly hard and soft materials can be obtained from this test. The Knoop and Vickers tests are classified as microhardness tests. The Brinell and Rockwell tests are ...
1
KHN
VHN
RHN
BHN
Dental
null
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single
Most abundant complement in the body
C3 is the most abundant complement.
3
C1
C2
C3
C4
Microbiology
null
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single
Use of oral contraceptives decreases the incidence of all of the following except:
null
3
Ectopic pregnancy
Epithelial ovarian malignancy
Hepatic adenoma
Pelvic inflammatory disease
Gynaecology & Obstetrics
null
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multi
Which of the following is not formed sphincter of oddi complex?
Sphincter of oddi complex:- 1. sphincter ampullae 2. sphincter pancreaticus 3. superior choledochal sphincter 4. inferior choledochal sphincter
4
Sphincter pancreaticus
Sphincter ampullae
Superior choledochal sphincter
Posterior choledochal sphincter
Surgery
Bile duct
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Disorders associated with vitiligo EXCEPT?
DISORDERS ASSOCIATED WITH VITILIGO Thyroid disease: Hypehyroidism Hypothyroidism Pernicious anemia Addison's disease Diabetes mellitus Hypoparathyroidism Myasthenia gravis Alopecia areata Morphoea and lichen sclerosis
1
Androgenic Alopecia
Hypothyroidism
Addison's disease
Diabetes mellitus
Dental
Hypo Pigmentary Disorders
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multi
True signs of placental separation are all of the following. except?
Signs of placental separation Lengthening of cord A gush of fresh bleeding Suprapubic bulge, due to firm uterine fundus after placental separation, is the most specific sign A Flabby uterus means that the placenta is still probably stuck to the uterus and hence preventing its proper contraction
4
Fresh bleeding per vaginum
Firm Fundus
Permanent Lengthening of umblical cord
Round flabby uterus
Gynaecology & Obstetrics
Placenta - Types and their complications
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multi
A 12 year old girl presents with a 0.4 cm slightly raised strawberry coloured nodule in the skin of the abdomen below the umbilicus. It is present for many years and not changed in color or size. Diagnosis
Answer: c) Hemangioma (ROBBINS 9th ED, P-516)HEMANGIOMAHemangiomas are very common tumors characterized by increased numbers of normal or abnormal vessels filled with bloodMost are present from birth and initially increase in size, but many eventually regress spontaneouslyWhile hemangiomas typically are localized lesio...
3
Carcinoma
Melanoma
Hemangioma
Lymphoma
Surgery
Neoplasia
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The following methods can be used to detect the point mutation in the beta (β)-globin gene that causes sickle cell anemia, except -
To detect point mutation, DNA analysis is required. While northern blot is a test for study of RNA. Polymerase chain reaction, DNA sequencing and southern blot testing are rapid methods for DNA analysis, and can all be used to detect the point mutation in the globin gene.
4
Polymerase chain reaction with allele-specific oligonucleotide hybridization
Southern blot analysis
DNA sequencing
Northern blot analysis
Biochemistry
null
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multi
Treatment of choice for vocal nodule is
Treatment of vocal nodules Early cases of vocal nodules can be treated conservatively by educating the patient about the proper use of voice. With this treatment, many nodules in children disappear completely. Surgery is required for large nodules or nodules of long standing in adults. They are excised with precision u...
2
Radical excision
Microlaryngoscopic removal
Cryotherapy
Wait and watch
ENT
Larynx
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single
When selecting the colour of cement to use for cementing a porcelain jacket crown, the powder being tested is best mixed with:
Self-cured and dual-cured materials can be opaque or translucent, and those indicated for cementation of ceramic restorations are usually provided in several shades. Light-cured materials are indicated for bonding of laminated ceramic veneers (esthetic cements) or orthodontic brackets. Some esthetic resin cements used ...
1
Glycerin-water solution
Cement liquid
Alcohol
Only water
Dental
null
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single
Schneider's 1st rank symptoms seen in
Ku Schneider (1959) described symptoms which, though not specific to schizophrenia, were of great help in making a clinical diagnosis of schizophrenia. These are popularly called as Schneider's first-rank symptoms of schizophrenia (FRS or SFRS). He also described the second rank symptoms of schizophrenia (which were co...
4
Delusion
Hallucination
Schizoid personality
Schizophrenia
Psychiatry
Schizophrenia and other psychotic disorders
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multi
Moth eaten alopecia is seen with -
Ans. is 'b' i.e., Syphilis
2
Leprosy
Syphilis
Fungal infection
Cylindroma
Surgery
null
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single
Community diagnosis means
Community diagnosis refers to identification and quantification of health problems in a community in terms of moality and morbidity rates and ratios, and identification of their correlates for the purpose of defining those individuals or groups at risk or those in need of healthcare.Park 23e pg: 91
1
Quantifying and summarizing the impoant health problems and their associated sociodemographic characteristic in a community
Priority - wise listing of the common diseases seen in a community
Summarizing the standards of living lifestyle factors in a community
None of the above
Social & Preventive Medicine
Epidemiology
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A 2-year-old child with history of fall one year back with parietal bone fracture now presented with painful and growing parietal swelling.
(b) Growing fracture,Ref: Growing skull fractures: classification and management. Naim-Ur-Rahman et al Br J Neurosurg. (1994)Growing Fractures:* Also known as traumatic encephaloceles or leptomeningeal cysts* Skull fractures associated with an underlying dural tear may fail to heal properly.* Enlargement of the defect ...
2
Growing scalp hematoma
Growing fracture
Subdural hygroma
Chronic abscess
Pediatrics
Gastro Intestinal System
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multi
Non specific esterase is positive in all the categories of AML except -
Ans. is 'd' i.e., M6 o FAB classification divides AML into eight types M 0 to M7. o This scheme takes into account : ? i) The degree of maturation (MO to M3) ii) The lineage of leukemic blast (M4 to M7). Class Blast cells o Myeloperoxidase negative Mo minimally differentiatedAML o Auer rods negative o Express myeloid l...
4
M3
M4
M5
M6
Pediatrics
null
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multi
NOT a content of superior mediastinum
Mediastinum refers to the space between two lungs in thorax. SUPERIOR MEDIASTINUM Space above 2nd costal cailage CONTENTS: thymus, arch of aoa, superior venacava, pulmonary aeries, esophagus, trachea, T1 - T4 veebra, PICA - 1, 2. INFERIOR MEDIASTINUM Space below superior mediastinum, again divided into anterior, middle...
1
Pulmonary trunk
Thymus
Left superior intercostal aery
Arch of aoa
Anatomy
FMGE 2017
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single
A10-year-old girl present with polyuria and polydipsia with hypokalemia, hypercalciuria and metabolic alkalosis. What is the probable diagnosis?
Ans: (c) Bartter syndromeRef: Nelson Textbook of Pediatrics, 20th edition, Page 2534BARTTER SYNDROME (AUTOSOMAL RECESSIVE)Clinical Subtypes:Antenatal Bartter syndrome (Hyperprostaglandin E syndrome):Mutations-genes that encode the sodium potassium 2 chloride transporter NKCC2 (the site of action of furosemide) orThe lu...
3
Gitelmann syndrome
Liddle syndrome
Bartter syndrome
Alport's syndrome
Pediatrics
Kidney
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single
Best antagonist of morphine is –
Naloxone is the preferred specific antidote for morphine poisoning.
2
Nalorphine
Naloxone
Buprenorphine
Pentazocine
Anaesthesia
null
24806071-74e0-4121-85de-ff5dde9776a0
single
Filigree burns occur in ?
Ans. is 'a' i.e., Lightening Lightening burns Lightening refers to discharge of current between a negatively charged cloud and positively charged aicle on eah. During lightening, injuries result due to following mechanisms :- Direct effect of high voltage current. Heat, i.e. super heated air causing burns. Expanded and...
1
Lightening
Electrocution
Vitrilage
Infanticide
Forensic Medicine
null
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single
The most common cause for chronic cor pulmonale is
Answer is B (COPD): The most common cause of chronic cor puhnonale is chronic. obstructive pulmonary disease - Rubin's pathology
2
Recurrent pulmonary embolization
COPD
Cystic fibrosis
Bronchial Asthma
Medicine
null
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single
A 75-year-old thin cachectic woman undergoes a tracheostomy for failure to wean from the ventilator. One week later, she develops significant bleeding from the tracheostomy. Which of the following would be an appropriate initial step in the management of this problem?
The patient had a sentinel bleed from a tracheoinnominate aery fistula, which carries a greater than 50% moality rate. If the bleeding has ceased, then immediate fiberoptic exploration in the operating room is indicated. If the bleeding is ongoing, several stopgap measures can be attempted while preparing for median st...
3
Remove the tracheostomy and place pressure over the wound.
Deflate the balloon cuff on the tracheostomy.
Attempt to reintubate the patient with an endotracheal tube
Upsize the tracheostomy
Anaesthesia
Miscellaneous
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multi
A Sentinel pile indicates
Ans. c (Fissure in ano) (Ref. Bailey and Love Surgery 26th/1250; Ref. Q. 216 of MH-2007).SENTINEL PILE- This misnomer is given to a skin tag marking--and often containing within it--the distal end of an anal fissure, found usually in the posterior midline.
3
Internal hemorrhoids
Pilonidal sinus
Fissure in ano
Fistula in ano
Surgery
Anal Fissures
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single
Which of the following is not characteristic of visceral pain -
• Visceral pain is poorly localized, often the pain is referred or radiating • Pain of hollow viscus is often felt as a colic (it comes and goes to reappear again). • Highly localized types of damage to the viscera seldom cause severe pain • Often accompanied by vomiting and hypotension
4
Poor localisation
Diffuse in nature
High threshold
Very rapid adaptation
Surgery
null
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single
Hanup disease, limiting amino acid
It&;s an autosomal recessive disease. Absorption of aromatic amino acids from intestine as well as reabsorption from renal tubules are defective Patient improve when put on high protein diet with supplementation of niacin Hence the limiting amino acid is tryptophanRef: DM Vasudevan - Textbook of Biochemistry, 7th editi...
2
Tyrosine
Tryptophan
Rhenylalanine
null
Biochemistry
Metabolism of protein and amino acid
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multi
All of the following statements about Lymphoepethelioma of the parotid gland are true, except:
Lymphoepithelioma occur chiefly in the nasopharynx of young or middle aged persons. It also seen in the oropharynx, tongue, tonsil, parotid, nasal chamber and paranasal sinus. Ref: Shafer'S Textbook of Oral Pathology By Rajendran, 6th Edition, Pages 119-120; Epstein-Barr Virus By Erle S. Robeson, Page 60
1
Parotid gland is the most common site of Lymphoepethelioma in the Head & Neck region
It is associated with EBV infection
It is highly radiosensitive malignancy
It is a squamous cell carcinoma
Surgery
null
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multi
Which of the following structure is not present in the transpyloric plane?
Transpyloric plane- An imaginary plane that passes at the lower border of L1 vertebra posteriorly and the tip of 9th costal cartilage anteriorly. Structures at the Transpyloric plane -        Pylorus of stomach -        Hilum of kidney -        Beginning of duodenum -        Neck of pancreas -        Fundus of gallblad...
4
First lumbar vertebra
Fundus of gall bladder
Hilum of right kidney
Inferior mesenteric vein
Anatomy
null
505b1349-ff1c-4f9a-bd40-899cc6f5e4f9
multi
Most common benign tumour of the stomach is ?
Ans. is 'a' i.e., Adenoma E ihtelial nolvus are the most common benign tumor of the stomach. They are of 5 types: a) Hyperplastic (regenerative) most common type (75%), with low malignant potential b) Adenomatous second most common, with high malignant potential (should be removed when diagnosed) c) Hamaomatous d) Infl...
1
Adenoma
Lipoma
Hamaoma
Leiomyoma
Surgery
null
f9aaa62f-8d57-4c38-8c84-10d42d216f9c
single
All are true regarding myositis ossificans progressive except
B i.e. Progressive form of normal myosites Fibrodysplasia (Myositis) Ossificans Progressiva Patho Histology - It is a rare autosomal dominant (AD) disorder of connective tissue differentiation. - Main pathogenic mechanism is defective regulation of the induction of endochondral ossification - Intense perivascular lymph...
2
Usually involve childs
Progressive form of normal myositis
Respiratory problems
Ankylosis
Surgery
null
8319effe-78c9-4d3f-9638-296bb6dbbdc6
multi
Meningococcal polyvalent vaccine is routinely recommended to:
Ans. b. All healthy children between 5-7 years of age (Ref: Park 23/e p166, 22/e p157)'Quadrivalent (polyvalent) vaccines are administered as a single dose to individuals aged >_ 2 years.'- Park 22/e p157Meningococcal VaccinesPolysaccharide VaccinesConjugate Vaccines* Available against Meningococci of serogroup A, C, W...
2
Adolescents young males
All healthy children between 5-7 years of age
More than 50 years of age diabetic patients on regular insulin
40 years old paramedical staff working in laboratory
Social & Preventive Medicine
Meningococcal Meningitis
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multi
Drug not causing exatithematous skin eruption –
Drugs causing exanthematic reactions Most common : - Ampicillin and penicillin, Phenylbutazone and other pyrazolones, Sulphonamides, Phenytoin, Carbamazepine, Gold, Gentamicin, Meprobamate, Atropine Less common : - Cephalosporins, Barbiturates, Thiazides, Naproxen, Isoniazid, Phenothiazines, Quinidine.
2
Phenytoin
Hydrocortisone
Ampicillin
Phenylbutazone
Dental
null
69623aa4-fcd6-4514-aba4-2992aa6a2dc6
single
A 34-year-old woman is seen in the emergency depament. About 5 hours previously, she began to have nausea, vomiting, abdominal cramps, and diarrhea. She then developed double vision, which prompted her to ask her husband to bring her to the emergency depament. When she is asked to go into the examining room, she stumbl...
This is a typical presentation of botulism, which is caused by the preformed toxin of Clostridium botulinum. Patients develop a progressive flaccid paralysis that can lead to death if their respiratory system is not adequately suppoed. Mentation is intact in these patients, and they do not exhibit sensory changes excep...
1
Clostridium botulinum
Clostridium perfringens
Clostridium ramosum
Clostridium septicum
Microbiology
null
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single
The rectum measures
The adult rectum is approximately 12-18 cm in length and is conveniently divided into three equal pas: the upper third, which is mobile and has a peritoneal coat; the middle third where the peritoneum covers only the anterior and pa of the lateral surfaces; and the lowest third, which lies deep in the pelvis surrounded...
4
18 cm
22 cm
17 cm
15 cm
Surgery
G.I.T
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single
Tardy ulnar neuritis may be due to
B i.e. Cubitus valgus deformity
2
Advanced osteo ahritis of elbow
Cubitus valgus deformity
Both of the above
None of the above
Surgery
null
0569ce46-9396-4e0d-94fc-e9fd04e6cca2
multi
Which of the following can be a homologous substitution for valine in hemoglobin
null
2
Isoleucine
Glutamic acid
Phenylalanine
Lysine
Biochemistry
null
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single
Hemorrhagic cystitis is caused by :
Cyclophosphamide is a prodrug and is activated by hepatic biotransformation to aldophosphamide. One of its degrada­tion products is acrolein that is responsible for hemorrhagic cystitis (its characteristic adverse effect). This adverse effect can be decreased by vigorous hydration and by the use of mercapto ethane sulf...
1
Cyclophosphamide
6 Mercaptopurine
5 Fluorouracil
Busulfan
Pharmacology
null
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single
In myasthenia gravis , all of the following are true except
Overall, women are affected more frequently than men, in a ratio of ~3:2. The cardinal features are weakness and fatigability of muscles. The weakness increases during repeated use (fatigue) or late in the day and may improve following rest or sleep. Unrelated infections or systemic disorders can lead to increased myas...
4
Women are more frequently affected than men
Bulbar weakness is especially prominent inMuSK antibody- positive myasthenia gravis.
Unrelated infections or systemic disorders can lead to increased myasthenic weakness
Tongue muscles are spared
Medicine
C.N.S
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multi
Factor IX deficiency results in increased -
Ans. is 'b' i.e., PTT (Partial thromboplastin time) o Partial thromboplastin time (PTT): It tests the intrinsic and common coagulation pathways. So, a prolonged PTT can results from deficiency of factor V, VIII (factor VIIIc, Von willebrand factor), IX, X, XI, XII, prothrombin or fibrinogen.o Prothrombin time (PT): It ...
2
PT (Prothrombin Time)
PTT (Partial thromboplastin time)
BT (Bleeding Time)
TT (Thrombin time)
Pathology
Bleeding Disorders
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single
All of the following can be done with Individual as a unit except
Health education can be done individually BUT limitation is that the numbers we reach is really small, and health education is given to only those who come in contact with health system.
2
Drug administration
Health education
Vaccination
Case report
Social & Preventive Medicine
null
25d04c1f-db76-43d7-81d6-3d43525c4ab1
multi
Precursor of norepinephrine -
Ans. is 'b' i.e.. Tyrosine
2
Tryptophan
Tyrosine
Methionine
Asparagine
Biochemistry
Miscellaneous (Structure & Function of Proteins)
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single
Persistent foetal lobulation of adult kidney is due to
In humans, embryologically, the kidneys originate as distinct lobules that fuse as they develop and grow. The lobulation of the fetal kidney is usually lost as the lobules become bonded together by the growth of new coex and the renal capsule. Persistent fetal lobulation is a normal variant seen occasionally in adult k...
4
Congenital renal defect
Obstructive uropathy
Intrauterine infections and scar
Is a normal variant
Surgery
Urology
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single
CMV retinitis in HIV occurs when teh CD4 counts falls below -
CD4 count<100 cells/mm3 REF:<\p> MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.473 case-3
2
50
100
200
150
Microbiology
Virology
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multi
Drop metastases is seen in
Drop metastases - Dissemination through CSF giving rise to nodular masses at some distance from primary tumour. It is seen in Medulloblastoma
1
Medulloblastoma
Ependymoma
Cerebellar astrocytoma
Neuroblastoma
Pediatrics
null
40aeabaa-c021-4196-a644-a4134a6665c8
single
Intra epidermal Bulla is seen in :
Ans. is 'b' Pemphigus "Pemphigus causes intraepidermal blistering because of loosening of desm somal links b/w epidermal cells caused by immunological attack- Roxburg, 16/e
2
Pemphigoid
Pemphigus
Dermatitis Herpetiformis
Light reaction
Skin
Pemphigoid Group
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single
A young patient has a midline, tender swelling in neck occurring after an attack of sore throat. The diagnosis is -
Diagnosis in this case is subacute thyroiditis. Symptoms are more severe in acute thyroiditis with complications and acute thyroiditis is more common in children. Just take a look of acute thyroiditis. • Acute thyroiditis is rare and due to suppurative infection of the thyroid. • More common in children and often is pr...
3
Acute thyroiditis
Thyroglossal cyst
Sub acute thyroiditis
Toxic goiter
Surgery
null
a8f94c80-04ea-4319-bb88-c28d33a26269
single
Delorme's operation is for
Ans. B. Rectal prolapse. (Ref. LB 25th pg. 1225)RECTALPROPLASE# It may be mucosal or full thickness (whole wall included).# Commences as rectal intussusception.# In children, the prolapse is usually mucosal an should be Rxed conservatively.# In the adults, the prolapse is often full thickness and is frequently asociate...
2
Solitary rectal ulcer
Rectal prolapse
Rectal stricture
Rectal carcinoma
Surgery
Rectum
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single
All of the following are true about Hepcidin except
Hepcidin, a 25-amino acid peptide secreted by hepatic Kupffer's cells downregulates duodenal iron absorption by regulating DMT1 activity as well as other proteins in the iron-responsive pathways (e.g., FP1). Hepcidin is a negative regulator of iron absorption because mice that fail to express hepcidin have elevated bod...
4
It is a 25- amino acid peptide secreted by Kupffer cells
Decreases duodenal absorption of iron
It regulates activity of transpoers DMT - 1 and ferropoin - 1
Mice with enhanced hepcidin expression have elevate body iron stores
Physiology
General physiology
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