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Narrowest part of esophagus is at?
Ans. is 'a' i.e., Cricopharyngeal sphincter * The narrowest part of esophagus is its commencement at the cricopharyngeal sphincter.
1
Cricopharyngeal sphincter
At the Aortic constriction
At the crossing of left principal bronchus
At the diaphragmatic opening
ENT
Oesophagus
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In methyl alcohol poisoning there is CNS depression, cardiac depression and optic nerve atrophy. These effects are produced due to:
Ans. (A) Formaldehyde and formic acid(Ref: Katzung 11/e p1024; KDT 8/e p422)Methyl alcohol (methanol) is metabolized to formaldehyde by alcohol dehydrogenase and then to formic acid by aldehyde dehydrogenase. These compounds are responsible for the toxicity. Formic acid can lead to coma and blindness also. Therefore, i...
1
Formaldehyde and formic acid
Acetaldehyde
Pyridine
Acetic acid
Pharmacology
Opioids
64df6148-9253-41f8-82e5-7945409a9eff
single
Selective Alpha 2a agonist is
Clonidine, Tizanidine are selective alpha 2 agonists. But dexmedetomidine is more selective acting on Alpha 2a receptors-cause sedation. Used as pre-anesthetic medication. Ref: H.L. Sharma 3rd ed Pg:179
4
Tizanidine
Terazosin
Yohimbine
Dexmedetomidine
Pharmacology
Cardiovascular system
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Management of Typical Febrile seizures include except
Sponging, paracetamol ibuprofen ,intermittent diazepam are treated for febrile seizures Most children with typical febrile seizures do not require specific treatment except for vigorous antipyretic therapy during febrile illnesses. Children experiencing excessively frequent or prolonged febrile seizures may be treated ...
4
Sponging
Paracetamol Ibuprofen
Intermittent Diazepam
Prophylactic phenobarbitone
Pediatrics
Central Nervous system
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Mineral with antioxidant property:
Ans. b (Selenium). (Ref. Harper, Biochemistry, 25th ed., 659,766)SeleniumFeaturesConstituent of glutathione peroxidaseSynergistic anti-oxidant with vitamin EEssential trace elementSelenocysteine is an L--amino acid found in a handful of proteins. As its name implies, a selenium atom replaces the sulfur of its structura...
2
Molybdenum
Selenium
Copper
Zinc
Biochemistry
Vitamins and Minerals
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Tall R wave in ECG represents:
Right ventricular hypertrophy due to a sustained, severe pressure load (e.g. due to right pulmonary valve stenosis or certain pulmonary artery hypertension syndromes) is characterized by a relatively tall R wave in lead V, (R >S wave), usually with right axis deviation.
3
Right atrial overload
Left atrial overload
Right ventricular hypertrophy
All of the above
Medicine
null
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multi
Best test for determining initial stage of renal insufficiency?
Serum creatinine REF: Harrison's Internal Medicine 17' edition chapter 274 The most impoant initial diagnostic step in the evaluation of a patient presenting with elevated serum creatinine is to distinguish newly diagnosed CKD from acute or subacute renal failure because the latter two conditions may respond to therapy...
1
Serum creatinine
Creatinine clearance
Glomerular filtration rate
Serum urea
Surgery
null
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single
Muscle relaxant of choice in patient suffering from chronic liver disease
Atracurium is preferred in CLD patients since it is metabolised by Hoffmann elimination.
2
Pancuronium
Atracurium
Mivacurium
Vecuronium
Anaesthesia
null
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The most comprehensive indicator of cost-effective analysis is
Cost-benefit analysis, in which benefits are compared to cost of the program. The benefits are expressed in monetary termsA cost-effective analysis is similar to cost-benefit analysis except benefits are expressed in terms of results achievedThe most commonly used outcome measure is quality-adjusted life years (QALY)Pa...
3
Number of life years gained
Number of hea attacks avoided
QALYS gained
Cost per life year gained
Social & Preventive Medicine
Health education & planning
366154db-4d54-4a4c-a6b0-d0d655f229ed
single
True about surgical wounds are all except
Preoperative antibiotic prophylaxis does not significantly reduce the frequency of postoperative wound infection in clean elective general surgical operations.So the routine prophylactic use of antibiotics in clean general surgical operations is not recommended. Incision of abscess comes under diy wounds. Infection rat...
2
No antibiotics required in clean surgery
Incision of abscess is contaminated wound
Spillage of stomach content conves a clean contaminated case to a contaminated case
In clean contaminated wounds infections rate is < 10%
Surgery
General surgery
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An investigator into the life expectancy of IV drug abusers divides a sample of patients into HIV-positive and HIV-negative groups. What type of data does this division constitute?
Nominal data (also known as nominal scale) is a type of data that is used to label variables without providing any quantitative value. Given question is about HIV-positive and HIV-negative groups; since there is no order of characteristic and it cannot be measured directly. So,it can't be an ordinal data or metric data...
1
Nominal
Ordinal
Interval
Ration
Social & Preventive Medicine
Variables, Scales
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Working formulation in staging of non-hodgkins lymphoma is based on: March 2010
Ans. A: Morphology of cells The 1982 Working formulation is a classification of non-hodgkin lymphoma. It excluded the Hodgkin lymphomas and divided the remaining lymphomas into four grades (Low, Intermediate, High, and Miscellaneous) related to prognosis, with some fuher subdivisions based on the size and shape of affe...
1
Morphology of cells
Cell surface markers
Survival characteristic of cells
Cellular genetics
Medicine
null
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Which condition is associated with Congenital Adrenal Hyperplasia?
(B) Female pseudohermaphroditism[?]Congenital Adrenal Hyperplasia (CAH) is the most common cause of female pseudohermaphroditism & virilization, & decreased cortisol synthesis owing to reduction or loss of 21-hydroxylase enzyme function is the most common biochemical cause of CAH.ABERRANT SEXUAL DIFFERENTIATION DEVELOP...
2
Male pseudohermaphroditism
Female pseudohermaphroditism
Female true hermaphroditism
Sequential pseudohermaphroditism
Pediatrics
Endocrinology
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multi
Which of these is not responsible for removal of free radicals?
Ans. (c) NADPH oxidase(Ref: R 9th/pg 48; 8th/pg 13,14)AntioxidantsEnzymesNon enzymes* Catalase- Present in peroxisomes Q decomposes H2 O2 Antioxidants- vitamins E, A and C glutathione in the cytosol.*. Superoxidase dismutases: O2- to H2 O2 *. Manganese-SOD, which is localized in mitochondria,*. Copper-zinc-SOD, which i...
3
Catalase
Superoxide Dismutase
NADPH oxidase
Glutathione peroxidase
Pathology
Cellular Pathology
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All are true about central retinal artery occlusion (CRAO) except?
Ans. (a) Most commonly occurs due to thromboembolism; (c) Sudden painful loss of visionRef: Kanski 7/e, p. 559, 563* Presentation is with sudden and profound loss of vision, Painless, except in Giant cell arteritis* Atherosclerosis related thrombosis at the level of lamina cribrosa is by far the most common underlying ...
1
Most commonly occurs due to thromboembolism
Anterior chamber paracentesis is used for treatment
Sudden painful loss of vision
Occurs due to obstruction of retinal artery at the level of lamina cribrosa
Ophthalmology
Retina
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Pseudomonas exotoxin inhibits protein synthesis by inhibiting ?
Ans. is 'b' i.e., EF-2 Exotoxin 'A' of P. aeruginosa inhibits protein synthesis through interference with adenosine diphosphate ribosylation of elongation factor - 2. Remember Bacterial toxins inhibiting protein synthesis : Exotoxin A of P aeruginosa Shiga toxin (Shigella) Diphtheria toxin Shiga like toxin or verocytot...
2
RNA polymerase
EF-2
Transpeptidase
Reverse transcriptase
Microbiology
null
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Filigree burn occur in -
FILIGREE BURNS OR ARBORESCENT OR LICHTENBERG'S FLOWERS: occur due to lightning injury These are superficial thin irregular and touous markings on the skin resemble branches of a tree the fernlike pattern of erythema in the skin usually on shoulders and flanks may develop instantly or within a few minutes CAUSES: 1. Sta...
1
Lightening
Electrocution
Vitrilage
Infanticide
Forensic Medicine
Thermal injury
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Wave length of UV A2 rays is
Ultraviolet light * Ultraviolet light (UV) is made up of: # Vacuum UVC (10-200 nm) # UVC (200-280 nm) # UVB (280-320 nm) # UVA (320-400 nm) divided into UVAII (320-340 nm) and UVAI (340-400 nm). Ref:- Review of Dermatology by Alikhan; pg num:-13
3
200nm to 280nm
280nm to 320nm
320nm to 340nm
340nm to 400nm
Dental
Anatomy of skin
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Which of the following is not a step in the ‘three step build up’ of direct filling gold?
A. Three step build-up for the restoration “Tie formation” This involves connecting two opposing point angles or starting points filled with gold with a transverse bar of gold. Such a “tie” forms the foundation for any restoration in direct gold. Of course, its resistance to displacement should be tested before proce...
2
Tie formation
Stepping
Shoulder formation
Banking of walls
Dental
null
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multi
Soft tick transmits –
null
1
Relapsing fever
KFD
Tularemia
Indian tick typhus
Social & Preventive Medicine
null
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single
Helitrope rash is seen in:
Dermatomyositis
4
SLE
Lichen Planus
Pitryiasis alba
Dermatomyositis
Skin
null
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single
Hypoglossal nerve is related to -
Hypoglossal nerve is a content of both digastric and carotid triangles.
3
Digastric triangle
Carotid triangle
Both
null
Anatomy
null
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Not true about content composition of an Egg is:-
Egg composition: - 6g - Fat - 6g - Protein - 30 mg - Calcium - 1.5 mg - Iron - 70 Kcal - Energy - 250 mg - Cholesterol Also remember, egg is Richest sources of cholesterol. Height NPU (Net protein utilization) - 96, hence known as reference protein. Poor In carbohydrates & vit c.
4
6 grams proteins
6 grams fat
1.5 mg Iron
150 mg Cholesterol
Social & Preventive Medicine
Proteins, Fats, Rich Sources
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Obstruction to the flow of CSF at the aqueduct of sylvius will most likely lead to enlargement of:
. Both lateral and third ventricles
4
All of the ventricles
Only lateral ventricle
Only fouh ventricle
Both lateral and third ventricles
Pathology
null
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multi
Pulmonary veins develops from:
Development of pulmonary veinsAt 27-29 days' gestation, the primitive pulmonary vein appears as an endothelial out-pouching from either the posterior superior left atrial wall or from the central pa of the sinus venosus proximal to the primordial lung venous plexus.Connection between the primitive pulmonary vein and pu...
2
6th aoic arch
Primitive left atrium
Left common cardinal vein
Left vitelline vein
Anatomy
null
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single
Which of the following are alkylating agents:
ALKYLATI NG AGE NTS These compounds produce highly reactive carbonium ion intermediates which transfer alkyl groups to cellular macromolecules by forming covalent bonds. The position 7 of guanine residues in DNA is especially susceptible, but other molecular sites are also involved. Alkylation results in cross linking/...
1
Cyclophosphamide
Ifosfamide
Paclitaxel
Methotrexate
Pharmacology
Chemotherapy
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Average gain in length in first year is
Length at bih- 50cms At 3 months- 60cms At 6 months- 65cms At the end of 1st yr- 75cms Hence gain in length in first year is (75-50= 25cms) Ref: Ghai,9th edition, Table 2.1
1
25cms
50cms
75cms
100cms
Anatomy
General anatomy
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A 63-year-old woman presents with symptoms of palpitations and atrial flutter on the ECG. Which of the following is the most likely mechanism of this arrhythmia?
Atrial flutter is characterized by regular atrial activation with an atrial rate of > 240 beats/min. The ventricular response depends on the conduction of the AV node, usually there is 2:1 or 3:1 conduction. It is now known that the predominant mechanism for atrial flutter is right atrial macro reentry with circular ac...
3
atrial asystole
atrial bigeminy
right atrial macro-reentry
AV nodal reentry
Medicine
C.V.S.
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Autosomal recessive disease have incidence of 1/ 250000 in a population. What is the carrier state of population?
.incidence is calculated as the total number new cases in a given time period divided by population at risk during that period.multiplied by 1000.so here total no of carrier states is given by 1divided by 250000 multiplied by 1000,that is 1/250. ref:park&;s textbook,ed 22,pg no 58
1
1\/250
1\/500
1\/1000
1\/5000
Social & Preventive Medicine
Epidemiology
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single
The laryngeal mask airway allows positive pressure ventilation with maximum pressure of:-
The LMA allows a positive pressure of 20 cm of H2O for ventilation .
2
10 cm H2O
20 cm H2O
30 cm H2O
40 cm H2O
Anaesthesia
Airway
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multi
Elderly primi is above :
30 years
1
30 years
35 years
37 years
45 years
Gynaecology & Obstetrics
null
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multi
Shoulder pain post laparoscopy is due to
Laparoscopy Needle used for pneumoperitoneum : Veress needle Most commonly used gas: CO2 Flow of gas : 1L/min Intra abdominal pressure : 12-15mmHg Trocar is inseed at or just below the umbilicus penetrating skin, superficial & deep fascia, fascia transversalis & parietal peritoneum Post-laparoscopy shoulder pain is due...
2
Subphrenic abscess
CO2 retention
Positioning of the patient
Compression of the lung
Surgery
Urology
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A 20 year old primigravida is admitted with-term pregnancy and labour pains. At 4.00 AM she goes into active labor. Membrance rupture during p/v exmination showing clear liquor. A repeat p/v examination after 4 hours of good uretine contractions reveals cervical dilataion of 5 cm. What should be the next step in manage...
Reassess for occipitoposterior position and cephalopelvic dispropoion
4
Reassess after 4 hours
Immediate cesarean section
Oxytocin drip
Reassess for occipitoposterior position and cephalopelvic dispropoion
Gynaecology & Obstetrics
null
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All of the following statements about mosquito are true except -
Man is the definitive host and mosquito is the intermediate host of Bancroftian and Brugian filariasis. Park's Textbook of Preventive and Social Medicine, 25th edition, Page No. 832
2
It is definitive host in malaria
It is a definitive host in filaria
Its life cycle is completed in 3 weeks
The female can travel upto 3 kilometers
Social & Preventive Medicine
Environment and health
3de6c2e1-a9d9-43a2-9e67-00d621063fc7
multi
First line of treatment of osteoporosis in postmenopausal woman?
Hormone replacement therapy is cornerstone in both prophylaxis and treatment of osteoporosis in menopausal women. Estrogen delays and protects against osteoporosis by 50% in all skeletal and not limited to trabecular bones of spine, wrist and upper hip. Rest of the drugs used in H for osteoporosis are natural estrogens...
1
Estrogen
Calcium and vitamin D supplementation
Bisphosphonates
Ulipristal
Gynaecology & Obstetrics
NEET Jan 2020
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single
Medical etiquettes are between which of the following categories?
Medical etiquette deals with the conventional laws of couesy observed between members of the medical profession. A doctor should behave with his colleagues as he would have them behave with himself. Ethical behaviour is a self-imposed duty upon each doctor. A doctor should not criticise or denigrate the professional ab...
1
Medical professionals
Medical professionals and pharmaceutical companies
Medical professionals and patients
Pharmaceutical companies and patients
Forensic Medicine
null
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Drugs used in GTCS is/are:
Carbamazepine, phenytoin are the first line drugs in GTCS. Valporate, phenobarbitone are the second choice of drugs. Alternative/add on drugs are Lamotrigine, Gabapentine, topiramate, methadone, levetiracetam. Ethosuximide is used in absent seizures. Propofol is a general anesthetic. Ref: K D Tripati 8th edition Table ...
2
Ethosuximide
Sodium-valproate
Lamotrigine
Propofol
Pharmacology
Central Nervous system
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single
Which of the following is the best parameter for monitoring septic shock?
Definitions of sepsis, severe sepsis, and septic shock Sepsis category Sepsis-3 2001 Sepsis CMS Sep-1 Sepsis SOFA score> 2 + suspected infection 2 of 4 SIRS criteria + suspected infection 2 of 4 SIRS criteria + suspected infection Severe Sepsis Not applicable Sepsis + organ dysfunction, hypoperfusion or hypotension Sep...
4
Central venous pressure (CVP)
Vasopressor requirement
Urine output
Serum lactate
Surgery
Shock
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'Foification spectra' are feature of NOT RELATED-PATHOLOGY
.
4
Mature cataract
Immature cataract
Amaurosis Fugax
Migraine
Pharmacology
All India exam
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single
Strength of wound after 2 months is governed by-
Ans. is 'a' i.e., Collagen cross linking Wound strengtho At the end of first week, wound strength is approximately 10% that of normal skin,o Strength increases rapidly over the next 4 weeks.o At the end of third months, the strength reaches a plateau of about 70 to 80% of the normal skin, a condition that may persist f...
1
Collagen cross linking
Excess collagen deposition
Both 'a' and 'b'
None of the above
Unknown
null
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multi
Agent of first choice in an acute attack of Prinzmetal's angina is:
Answer is B (Nitrates) "Sublingual nitroglycerine is the drug of choice" -- CMDT Nitrates decrease aeriolar and venous tone, reduce preload and afterload, and reduce the oxygen demand of the hea. Nitrates may also improve myocardial blood flow by dilating collateral channels in the presence of increased vasomotor tone,...
2
Diltiazem
Nitrates
Propranolol
Verapamil
Medicine
null
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single
Which of the following is a cognizable offence
Refer the byte "Cognizable and Non cognizable offences".
4
Ragging
Robbery
Dowry death
All of the above
Forensic Medicine
null
bb29358c-c5bd-44de-9783-0142725933ce
multi
A 53-year-old woman with ovarian tumor presents with breathlessness and right-sided chest pain. The chest X-ray shows obliteration of the right costophrenic angle. Diagnosis?
Ans. A PleurisyRef. CMDT 2019 pg. 323Ovarian tumor (Fibroma and thecoma) can be associated with a right-sided pleural effusion (Meigs syndrome). The obliteration of CP angle on X-ray is another pointer for pleural involvement of this patient.
1
Pleurisy
Pericarditis
Myocardial infarction
Parapneumonic effusion
Physiology
Heart, Circulation, and Blood
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All of the following statements about Philadelphia Chromosome in CML are true, except:
Answer is D (The Philadelphia chromosome with the oncogenic BCR-ABL gene is found on chromosome 9) The Philadelphia chromosome with the oncogenic BCR-ABL gene fusion is the truncated chromosome 22 (and not chromosome 9). The Philadelphia chromosome results from a reciprocal translocation between the ABL-1 oncogene on t...
4
Reciprocal translocation between long arm of chromosome 9 and long arm of chromosome 22
The breakpoint cluster region (BCR) is located on the long arm of chromosome 22
The ABL gene is located on chromosome 9
The Philadelphia chromosome with the oncogenic BCR-ABL gene is found on chromosome 9
Medicine
null
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multi
Not a predisposing factor for Ca esophagus:
null
3
Diverticula
Human papilloma virus
Mediastinal fibrosis
Caustic ingestion
Surgery
null
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Post-styloid space of parapharyngeal space contains all, EXCEPT:
The parapharyngeal space is a potential space, shaped like an inveed pyramid spanning the skull base to the hyoid. The boundaries of the space are separated by the styloid process and its associated fascial attachments into the "prestyloid" and "poststyloid" compaments. The contents of the prestyloid space are the paro...
3
Cranial nerve IX
Cranial nerve XII
Parotid
Lymph nodes
Surgery
null
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multi
Which of the following is used with local anesthetics to potentiate their action?
Adrenaline is a vasoconstrictor that prolongs duration of local anesthetics & prevents systemic toxicity. Sodium bicarbonate speeds the action of local anesthetics by increasing the unionized form.
2
Adrenaline
Sodium bicarbonate
Both 1 & 2
Dantrolene
Pharmacology
null
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multi
8 yrs. old child presents with lethargy multiple epiphyseal breaks, wormian bones with growth retardation and mental retardation Diagnosis is?
Ans. is 'b' Hypothyroidism (Ref. : O.RGhai, 6/e, p 482 (5/e, p447))Presence of mental retardation, growth retardation and wormian bones clinch the diagnosis in favour of hypothyroidism.In Hypothyroidism both mental retardation * and growth retardation * are present andthe skull X-ray shows large fontanelle, wide suture...
2
Rickets
Hypothyroidism
Scurvy
Hypoparathyroidism
Pediatrics
Thyroid Gland
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All are complication of PEEP except :-
Positive end expiratory pressure decreases venous return and decreases cardiac output and hence blood pressure decreases and decreased perfusion so urine output can reduce. Pulmonary barotrauma is a frequentcomplicationofPEEPtherapy. Pneumothorax, pneumomediastinum, and interstitial emphysema may lead to rapid deterior...
2
Decreased urine ouput
Increased blood pressure
Increased intracranial pressure
Increased intrathoracic pressure
Anaesthesia
Modes of Ventilation
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multi
Rate limiting step in Gluconeogenesis is catalyzed by -
Ans. is 'a' i.e., Fructose -1,6 phosphatase Rate limiting steps in various biochemical reactions taking place inside cells is of vital importance while formulating drugs to fight specific diseases affecting these reactions. So these rate-limiting steps are frequently asked in various entrance exams. Glycolysis - Phosph...
1
Fructose -1,6 phosphatase
Glucokinase
Glycerol kinase
PDH
Unknown
null
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multi
Differential force concept is mainly used in
null
3
Straight wire appliance
Lingual appliance
Begg's Light wire appliance
Frankel appliance
Dental
null
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single
A patient got his SBP reduced by 10mmHg when he stood up and he gained only 8mmHg. What was the gain?
Correction here is = –8mmHg Error persists even after correction = 10 – 8 = +2 Gain = Correction / Error           = –8 / +2           = –4
1
–4
4
–8
8
Physiology
null
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single
Triage refers to?
Ans. is `b' i.e., Categorization of patients according to level of severity Triage consists of rapidly classifying the injured and the likelyhood of their survival with prompt medical intervention.
2
Availability of level of medical care
Categorization of patients according to level of severity
Medical personnel skill level
None of the above
Social & Preventive Medicine
null
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multi
Lipoprotein involved in transfer of cholesterol from tissues to Liver is?
ANSWER: (D) HDLREF: Lippincott's biochemistry 4th Ed page 236See previous question
4
Chylomicron
LDL
VLDL
HDL
Biochemistry
Cholesterol and Lipoproteins
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single
Common dose dependant side effects of ethambutol is :
null
2
Red-urine
Optic neuritis
Nephropathy
Peripheral neuropathy
Pharmacology
null
0334c689-1ada-4eed-b40c-c93089815d23
single
Which type of pulmonary TB is most likely to give sputum positive -
Ans. is 'c' i.e., Cavitary "Sputum smears are usually positive in patients with laryngeal TB, endobronchial TB and cavitary pulmonary- TB"-- Kelley's"Patients with cavitary pulmonary TB have high bacterial load in their sputum " --Internet
3
Fibronodular
Pleural effusion
Cavitary
null
Microbiology
Bacteria
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multi
Drug given for metaclopramidr induced dystonic reaction is:
Acute muscle dystonia caused by antiemetic-antipsycotic drugs is promptly relieved by parentral promethazine or hydroxyzine.this is based on central anti cholinergic action of the drugs. Promethazine is an first generation anti histaminic which has maximum anticholinergic activity.(ref: KDT 6/ep157)
2
Pheniramine
Promethazine
Chlorpropamide
Prochlorperazine
Pharmacology
Gastrointestinal tract
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single
Run-Amok is a feature of :
Ans. is 'c' ie Cannabis Run-amok: is a condition resulting from the continued use of cannabis or even its consumption for the first time.It is characterized by a frenzied desire to commit murders.A number of individuals are killed, the first ones being those against whom the assailant has some real or imaginary enmity,...
3
Opium
Dhatura
Cannabis
Alcohal
Forensic Medicine
Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques
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single
Treatment of choice for uterine prolaspe in a 40-year- old married female with completed family?
Ans. C. Vaginal hysterectomy with pelvic floor repair. (Ref. Shaw Gynecology 15th/pg. 340; Novak's Gynecology 13th/pg. 290; Stenchever Gynecology 4,h/pg.580)UTERINE PROLAPSE# Woman < 20 yr old.unmarried=Sling Operation# Young Woman (20-40 yrs) of child bearing age = FothergilFs operation.# Woman > 40 yrs with completed...
3
Fothergill's operation
Abdominal Sling operation
Vaginal hysterectomy with pelvic floor repair
Ring pessary
Gynaecology & Obstetrics
Miscellaneous (Gynae)
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single
Ectopic rest of normal tissue is known as ?
Ans. is 'a' i.e., Choristoma o Normally arranged tissue at a different anatomical site (ectopic site) --> Choristoma. o Abnormally arranged tissue present at normal site -->Hamaoma
1
Choristoma
Hamaoma
Pheudotumor
Lymphoma
Pathology
null
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single
A 13 years boy presented with swelling in the cheek with recurrent epistaxis. Most likely diagnosis is
(Angio fibroma) (230-Dhingra 4th)* Nasopharyngeal Fibroma (Juvenile nasopharyngeal angiofibroma)Clinical features* Almost exclusively in male age 10-20 years* Profuse and recurrent epistaxis *** Progressive nasal obstruction and denasal speech* Conductive hearing and serous otitis media* Mass in the masopharynx* Other ...
1
Angiofibroma
Carcinoma nasopharynx
Rhabdomyosarcoma
null
ENT
Nose and PNS
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multi
Not a sign/symptom of aconite poisoning: JIPMER 12
Ans. Hypeension
3
Pain abdomen
Bradycardia
Hypeension
Diplopia
Forensic Medicine
null
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single
True about anal membrane
Before the urorectal septum has an oppounity to fuse with the cloacal membrane, the membrane ruptures, exposing the urogenital sinus and dorsal anorectal canal to the exterior. Later on, an ectodermal plug, the anal membrane, forms to create the lower third of the rectum. ref - Semantischolar.org ref - BDC vol2
3
Perforates at 6 weeks
Develops from anterior pa of cloacal membrance
Lies at proximal pa of proctodaeum
Covers urogenital sins
Anatomy
Abdomen and pelvis
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multi
Which of the following is the predominant cell type in the intra-epithelial region of small intestinal mucosa?
T lymphocyte predominantly of cytotoxic phenotype (CD8+) constitute the predominant cell type in the intra epithelial region of the mucosa of intestine. The lamina propria consist of helper T cells (CD4+) and educated B cells. Ref: Robbins Pathologic Basis of Disease, 6th Edition, Page 804
4
Basophils
Plasma cells
B lymphocyte
T lymphocyte
Pathology
null
cec41ed3-2906-41e1-b0be-40d15d285368
multi
A 6 year old boy has presented to you with progressive muscle weakness and difficulty in walking upstairs. He has difficulty in walking and has a waddling gait. On examinations Gower's sign is present and there is hypertrophy of calf muscles. His CPK is 10,000 IU. Which of the following is the most probable diagnosis?
Ans. A. Duchenne Muscular hypertrophyDuchenne muscular dystrophy (DMD) is a severe type of muscular dystrophy. The symptom of muscle weakness usually begins around the age of four in boys and worsens quickly. Females with a single copy of the defective gene may show mild symptoms. The disorder is X-linked recessive. Ea...
1
Duchenne Muscular dystrophy
Polymyositis
Dermatomyositis
Congenital myopathy
Pediatrics
Musculo Skeletal Disorders
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single
Contractile Dysfunction is the dominant feature of which of the following types of cardiomyopathies
Ref Harrison 19 th ed pg 1556 An enlarged left ventricle with decreased systolic function as mea- sured by left ventricular ejection fraction characterizes dilated car- diomyopathy ). Systolic failure is more marked than diastolic dysfunction. Although the syndrome of dilated cardiomyopathy has multiple etiologies, the...
1
Dilated cardiomyopathy
Restrictive cardiomyopathy
Hyperophic cardiomyopathy
Infiltrative cardiomyopathy
Anatomy
General anatomy
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single
Propaganda is :
null
3
Knowledge by active learning
Facilitates learning
Knowledge forced into the mind
Group discussion
Social & Preventive Medicine
null
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single
Banana shaped gametocytes in peripheral smear are seen in infection with:
Banana shaped or crescent shaped gametocytes are seen in P. Falciparum.
3
Plasmodium vivax
Plasmodium malaria
Plasmodium falciparum
Plasmodium ovale
Microbiology
Parasitology Pa 1 (Protozoology)
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single
HLA marker of bechet's syndrome ?
Ans. is 'c' i.e., HLA-B51
3
HLA-B27
HLA-DR5
HLA-B51
HLA-CW6
Pathology
null
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single
Drug of choice for night shift workers insomnia is
.
2
Methylphenidate
Modafinil
Amitriptyline
Adrenaline
Anatomy
General anatomy
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single
Polyhydramnios not seen in -
Ans. is 'b' i.e., Renal agenesis Etiology of Poivhvdrammoso Fetal anomaliesy Anencephalyy Open spina bifiday Esophageal or duodenal atresiay Facial clefts and neck massesy Hydropsfetalisy Aneuploidyo Placentay Chorioangioma of placentao Multiple pregnancyy Maternal diabetes: cardiac or renal disease.
2
Anencephalv
Renal agenesis
Hydropsfetalis
Chorioangioma of placenta
Gynaecology & Obstetrics
Hydramnios and Oligo Hydramnios
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single
Liver is divided into
null
1
8 Couinaud segments
7 Couinaud segments
9 Couinaud segments
10 Couinaud segments
Anatomy
null
20c49653-2a4a-4fa4-899b-bb8c2ac09edf
single
Treatment of choice of thoracic actinomycosis is:
Ans. is 'c' Penicillin Actinomycosis occur at different sites such as oro cervicofacial, thoracic, abdominal and pelvic.The drug of choice for all types of actinomycosis is penicillin.
3
Amphotericin B
Cotrimoxazole
Penicillin
Itraconazole
Medicine
Bacteriology
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single
28 yr old man presented with headache. CT head shows a low attenuation mass in left temporoparietal region which has similar density to CSF and shows no enhancement following contrast administration. Diffusion weighted MRI shows high signal. Which of the following is most probable diagnosis?
When there is Diffusion Restriction, DW-MRI gives a bright signal and has low apparent Diffusion Coefficient(ADC value). Lesions showing Diffusion Restriction Infarct(Acute Infarct)- IOC Abscess Medulloblastoma & Other Cellularity Tumours Epidermoid Cyst There is free diffusion of water within arachnoid cysts therefore...
3
Migraine
Arachnoid cyst
Epidermoid cyst
Multiple sclerosis
Radiology
Neuroradiology
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single
Treatment of lepromatous leprosy is
Ans. c (Rifampicin + Dapsone + Clofazimine); (Ref. Park PSM 22nd/pg. 296)Recommended regimens of chemotherapy for Leprosy in adultsFORM OF LEPROSYMORE INTENSIVE REGIMENWHO RECOMMENDED REGIMENLepromatous(multibacillary)Rifampin (600 mg/d) for 3 years plus dapsone (100 mg/d) indefinitelyDapsone (100 mg/d self-administere...
3
Rifampicin + Dapsone
Rifampicin + Clofazimine
Rifampicin + Dapsone + Clofazimine
Rifampicin + Ofloxacin + Minocycline
Social & Preventive Medicine
Communicable Diseases
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single
Commonest hemorrhage following head injury: KCET 13
Ans. Subdural hemorrhage
2
Extradural hemorrhage
Subdural hemorrhage
Intracranial hemorrhage
Subarachnoid hemorrhage
Forensic Medicine
null
a5aa292b-244b-4b38-bae1-b3876cff3149
single
All of the following are associated with Atrioventricular block, except:
Adrenal insufficiency is associated with Atrioventricular Block (Not cushing&;s syndrome). Metabolic/Endocrine Causes of AV Block: Hyperkalemia Hypermagnesemia Hypothyroidism Adrenal Insufficiency Ref: Harrison 19th edition Pg no: 1471
4
Hyperkalemia
Hypomagnesemia
Hypothyroidism
Cushing's syndrome
Medicine
C.V.S
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multi
Mantle cell lymphoma are positive for all of the following except:
Parameter CLL MCL SMZL/SL VL HCL FL PLL CD5 + + - - - - CD10 - -/+ - - + -/+ CD11c -/+ -/+ + + - + CD19 + + + + + + CD20 +(dim) +(bright) +(bright) +(bright) +(bright) +(bright) CD23 + -/+ -/+ - -/+ - CD79b - + - -/+ + + FMC7 - + + + + + Smlg +(dim) +(bright) +(bright) +(bright) +(bright) +(bright) CLL: Chronic lymphoc...
1
CD 23
CD 20
CD 5
CD 19
Pathology
Non Hodgkin Iymphoma
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multi
All are indicators of malignancy in a mammography except -
Answer (a) Nodular calcification
1
Nodular cacification
Speckled margin
Attenuated architecture
Irregular mass
Surgery
null
5365471d-9e64-4d32-b7fa-398eb078935c
multi
Substance for gluconeogenesis is
null
3
Glycogen
Acetyl CoA
Glycerol
Leucine
Biochemistry
null
ccd9585e-f874-49d4-9cb8-c83db1a32479
single
Methimazole differ from propylthiouracil in all except-
Ans. is 'c' i.e., More protein bound
3
Is secreated into milk
Has more volume of distribution
More protein bound
All
Pharmacology
null
e1ecb597-1892-47a4-afcb-d192f8d77286
multi
The pathological feature in wegener's granulomatosis on renal biopsy is
Robins..... 'The renal lesions range from a mild/early disease, where glomeruli show acute focal neorosis with thrombosis of isolated glomerulas capillary loops (focal and segmental necrotising glomerulonephritis) where as advanced glomerular lesions are characterized by diffuse necrosis and partial cell proliferation ...
2
Nodular glomerulosclerosis
Focal necrotising glomerulonephritis
Granulomas in the vascular wall
Granulomas in parenchyma of kidney
Pathology
null
932762ce-99bc-41df-ba4c-c27edb8fb411
multi
Dermatitis herpetifomis is associated with:-
Dermatitis herpetiformis occurs d/t gluten. HLA associated are: HLA B8 HLA A1HLA DQ2,DQ8, DR3 Psoriasis is associated with HLA CW6
2
HLA DR4
HLA B8, HLA DQ2 and HLA DQ8
HLA CW6
HLA DR2
Dental
JIPMER 2018
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single
Most frequent site of metastasis in a case of Choriocarcinoma is:
Lungs
3
Vagina
Liver
Lungs
Brain
Gynaecology & Obstetrics
null
32622299-fab0-427d-ab2a-e4de7aa4dbe1
single
Mechanism of action of Tubocurarine is
Tubocurarine is a non depolarizing muscle relaxant that competitively blocks action of Acetylcholine on its receptors.
3
Cholinesterase inhibitor
Cause membrane depolarisation
Competitive antagonist of acetylcholine receptor
Inhibit opening of chloride channels
Pharmacology
null
499ee636-e78e-4200-9cf6-614704a3f536
single
All are true regarding Menetrier's disease, EXCEPT:
Answer is B (Exophytic growth) Menetrier's disease is characterized hr hyperophy of gastric mucosa and not hr exoph;'tic growth. Menetrier's disease Menetrier's disease is a relatively rare disorder of the stomach characterized by lar e touous mucosal folds Etiology * Etiology is unknown * Over expression of growth fac...
2
Protein loss
Exophytic growth
Hyperophy of gastric mucosa
Premalignant condition
Medicine
null
1f5b8d55-56e5-474a-b7f6-9267a7374d2e
multi
All of the following are true about Raynaud's disease except
Raynaud's disease is a rare disorder of the blood vessels, usually in the fingers and toes. It causes the blood vessels to narrow when you are cold or feeling stressed. When this happens, blood can't get to the surface of the skin and the affected areas turn white and blue. When the blood flow returns, the skin turns r...
2
More common in females
Positive antinuclear antibodies
Most common cause of raynaud's phenomenon
Has good prognosis
Medicine
Immune system
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multi
An example of rigid reversible impression material is
null
2
Agar-agar
Impression compound
Alginate
Impression paste
Dental
null
d659b7b8-77d2-4e63-a7fc-da258432bf26
single
A patient is suspected to have vestibular shwanomma the investigation of choice for its diagnosis is -
MRI – MRI with gadolinium contrast is the gold standard for the diagnosis or exclusion of vestibular Schwannoma
2
Contrast enhanced CT scan
Gadolinium enhanced MRI
SPECT
PET scan
ENT
null
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single
Ovulation is associated with sudden rise in
Ovulation is associated with LH surge Ref: guyton and hall textbook of medical physiology 12 edition page number:641,642,643
3
Testosterone
Prolactin
LH
FSH
Physiology
Endocrinology
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single
All of the following changes are seen in pregnancy except :
CARDIAC OUTPUT: Increases from 5th week of pregnancy, reaches its peak 40-50% at about 30-34 weeks. Thereafter the CO remains static till term. CO is lowest in the sitting or supine position and highest in the right or left lateral or knee chest position. Cardiac output increases fuher during labor (+50%) and immediate...
4
Increased stroke volume
Increased cardiac output
Increased Intravascular volume
Increased peripheral vascular resistance
Gynaecology & Obstetrics
General obstetrics
38c32d39-8207-4c87-9e72-cc7bd7f64591
multi
The structure found in a cross-section of the thorax at T4 veebra is :
C i.e. Arch of aoa
3
Azygos vein
Brachiocephalic aery
Arch of the aoa
Left Subclan aery
Anatomy
null
16dadec7-9674-417b-bd4c-3a9bf0d46600
single
Three point relationship is reversed in all of the following conditions, EXCEPT:
The structures forming the three bony point around the elbow are medial epicondyle, lateral epicondyle and tip of olecranon. Normally in an elbow flexed at 90 degree these three points forms a near isosceles triangle. Base is formed by the line joining the two epicondyles. The three points lies in a straight line when ...
3
Medial epicondyle fracture
Lateral epicondyle fracture
Supracondylar fracture
Posterior elbow dislocation
Surgery
null
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multi
A 40 year old female patient complains of breathlessness. Patient is pregnant (3rd trimester) and is on bed rest. This patient is under-
null
1
High risk for thrombosis
Low risk for thrombosis
Risk for primary thrombosis
No risk for thrombosis
Pathology
null
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single
A 3-month-old infant is diagnosed with a membranous ventricular septal defect. A cardiac operation is performed, and the septal defect is patched inferior to the noncoronary cusp of the aorta. Two days postoperatively the infant develops severe arrhythmias affecting both ventricles. Which part of the conduction tissue ...
The bundle of His is a collection of specialized cardiac muscle cells that carry electrical activity to the right and left bundle branches. Because both ventricles are affected, this is the logical site of injury, for this bundle leads to the bundle branches supplying both ventricles. An injury either to the right or l...
3
Right bundle branch
Left bundle branch
Bundle of His
Posterior internodal pathway
Anatomy
Thorax
427c26fd-b1a0-4a91-b494-089adb511bf8
multi
The drug NOT used in psoriasis is
(B) Chloroquine # TREATMENT OF PSORIASIS: Locally by Topical coaltar.> Wide spread Psoriasis: by Ultraviolet fi-spectrum alone or along with coaltar (Geockerman regimen) or Anthranil (Ingram regimen)> Methotrexate Therapy: Methotrexate is drug of choice in Very Severe form of Psoriatic arthritis & Methotrexate is indic...
2
Psoralens
Chloroquine
Methotrexate
Coaltar
Skin
Miscellaneous
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single
A 35 year old sailor from a merchant ship that has been cruising the Caribbean presents to a clinician because of painful, flocculent masses in his groin. Physical examination demonstrates multiple enlarged, abscessed lymph nodes draining through the skin indolent sinuses. The sailor describes previously having a small...
This is lymphogranuloma venereum. The only other commonly discussed sexually transmitted disease in which they can occur is chancroid. Histologically, the buboes of lymphogranuloma venereum are enlarged lymph nodes with stellate abscesses. The primary lesion is usually a self-healing papule or shallow ulcer. The causat...
4
Condyloma acuminatum
Granuloma inguinale
Herpes virus infection
Lymphogranuloma venereum
Microbiology
null
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multi
Both hyperplasia and hyperophy are seen in
Ref,Robbins 9/e p36 The massive physiological growth of the uterus during pregnancy is a good example of hormone induced increase in size of an organ that results from both hyperophy and hyperplasia
2
Breast enlargement during lactation
Uterus during pregnancy
Skeletal muscle enlargement during exercise
Left ventricular hyperophy during hea failure
Anatomy
General anatomy
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multi
The drug of choice for the treatment of Thyrotoxicosis during pregnancy is:
Ans. is 'c' i.e. propylthiouracilRef.: K.D. T. 5th/e p 232, 4th/e p 259, 260This question has been repeated several times before, remember these important pointsAll antithyroid drugs can cross placenta so risk of fetal hypothyroidism and goitre is always thereBoth carbimazole and propylthiouracil can be used during pre...
3
Carbimazole
Iodine therapy
Propyl thiouracil
Metimazole
Pharmacology
Endocrinology
3bd54f9d-dd9d-4a31-adbd-5c673b5f81c5
single
Which of the following is false regarding Multiple Sclerosis (MS)?
Multiple sclerosis is an auto immune disease of central neural system with a relapsing and remitting or progressive course. The pathologic hallmark of disease is demyelination. Myelin specific antibodies are present on degenerating myelin sheaths. Surviving oligodendrocytes paially remyelinate surviving axons, which ar...
3
More common in women and age of onset is between 20-40 years of age
Risk factors include vitamin D deficiency and cigarette smoking
Pathological hallmark is axonal degeneration
HLA DRB1 in MHC class II is associated with 10% of disease risk
Medicine
All India exam
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multi