question
stringlengths
1
1.57k
exp
stringlengths
1
22.5k
⌀
cop
int64
1
4
opa
stringlengths
1
287
⌀
opb
stringlengths
1
287
⌀
opc
stringlengths
1
286
⌀
opd
stringlengths
1
301
⌀
subject_name
stringclasses
21 values
topic_name
stringlengths
3
135
⌀
id
stringlengths
36
36
choice_type
stringclasses
2 values
Bernoulli's principle states
Ans. (a) Sum of kinetic energy of flow and pressure energy is constantRef: Ganong, 25th ed/p.571Velocity of blood flow (kinetic energy) and the pressure (potential energy) are interrelated by the Bernoulli's principleBernoulli's principle#States that "The sum of the kinetic energy of flow and the potential energy--is c...
1
Sum of kinetic energy of flow and pressure energy is constant
Low tones producing maximal stimulation at apex of cochlea
Magnitude of the sensation felt is proportionate to the intensity of stimulus
Force of contraction is proportional to the stretch of cardiac muscle
Physiology
Heart, Circulation, and Blood
6db89580-4985-4093-bc59-e81da957b943
single
True about use of anticonvulsants and OCPs in epileptic patient is all except
Metabolic interactions between anticonvulsants and combined hormonal contraceptives usually do not result in increased seizure activity except for Lamotrigine.
3
OCPs may reduce efficacy of anticonvulsants
Those on Lamotrigine monotherapy, combined OCPs are not recommended
Their metabolic interactions usually increase seizure activity
OCPs containing atleast 30ug ethinyl estradiol should be used
Gynaecology & Obstetrics
null
8980b7e3-3ebf-4fe5-8bfa-300154813f0b
multi
Hunt Hess scale is used to grade manifestations of -
Ans. is 'a' i.e., Subarachnoid hemorrhage Subarachnoid hemorrhage:* The clinical state of a patient suffering from subarachnoid hemorrhage is highly predictive of the therapeutic outcome.* A grading system has therefore been developed to document the severity of patient's disease in order to guide therapy and prognosti...
1
Subarachnoid hemorrhage
Meningioma
Hydrocephalus
Tuberculous meningitis
Surgery
Nervous System
179b4288-2815-409b-96bf-d89a24ecd3a0
single
Effective leprosy control programme may be indicated by all of the following except –
Evaluation off programme: There are two main types of indicators in leprosy control a)  Operational indicators These are related to case-finding, treatment, relapses & disabilities for e.g. Relapse rate - One of the best indicators of the efficacy of drug regimen Case detection ratio - No. of cases registered / no. ...
1
Increasing number of children affected
Decreased grade 2 disability
Low MDR resistant, multibacillary cases
High new case detection rate
Social & Preventive Medicine
null
054c188e-4368-4416-880b-23e5ccb8a052
multi
All are actions of cholecystokinin except:
Ans. A. Increase gastrin secretionActions of CCK CONTRACTION OF GALLBLADDERSECRETION OF PANCREATIC JUICEInhibits gastric emptyingExerts atrophic effect on the pancreasIncreases the secretion of enterokinaseAugments the action of secretin in producing secretion of an alkaline pancreatic juiceEnhances the motility of sma...
1
Increase gastrin secretion
Increase lower esophageal sphincter pressure
Stimulation of pancreatic enzyme
Stimulation of gallbladder
Physiology
G.I.T.
903f4832-bad0-424e-8961-95acacac3087
multi
Which drug inhibits absorption of cholesterol from intestine?(DNB 2012-section-1)
Ans. (b) EzetimibeRef'.Harrison's 18/e, ch 356
2
Resins
Ezetimibe
Niacin
Orlistat
Pharmacology
Hypolipidemic
2e5d667e-eef9-4860-9253-6f456c1e689b
single
Hypochloremia, hypokalemia and alkalosis are seen in
Biochemical abnormality in congenital hyperophic pyloric stenosis is a regular feature of AIIMS and AI examinations it has been repeated several times. The biochemical abnormalities seen are: Hypokalemia Hypochloremia Alkalosis and Paradoxical aciduria Ref : Schwaz 9/e p59
2
Hirschsprung's disease
Congenital hyperophic pyloric stenosis
Esophageal atresia
Jejunal atresia
Anatomy
General surgery
5bb05983-c2d5-4fd4-bef5-907ec9b1c326
single
Which of the following lymphomas is associated with HTLV virus infection?
HTLV 1 causes adult T-cell leukemia/lymphoma
3
Burkitt's lymphoma
B-Cell lymphoma
Adult T cell leukemia and lymphoma
Hodgkin's disease
Pathology
Hematology: White Blood Cells (Miscellaneous questions)
aab036a6-1a30-4907-82eb-f5730bad09cc
single
In a blast injury , which of the following organ is least involved
Primary blast injuries result from the rapid overpressure or shock waves produced by an explosion* These injuries result from the dramatic changes in barometric pressure projected from the point of detonation* Primary blast injuries predominantly cause damage to air filled hollow organs of the body from rapid pressure ...
3
Lungs
Eardrum
Liver
GI tract
Surgery
Trauma
a9cf3125-9ffb-47ab-97eb-b045d11b2767
single
Which of the following toure techniques are known by the term 'Telefono'?
Bell (campana): a method of toure leaving no external marks in which a person's head is placed within a pail or other metal container which is then struck repeatedly, causing sudden loud sounds and reverberations Buzzer (chicharra): a method of toure in which the person is repeatedly shocked through wires or other cond...
2
Beating the soles of feet with a rod
Both ears are clapped
Repeatedly shocked through wires
Tying of a plastic bag over head
Forensic Medicine
null
b141fd57-7535-4209-9e95-ea42b6bdc6f6
multi
Runt's disease is associated with
GVHD Robbins, 7 edition, Page 222 * Runt's disease: is a pathological condition in which cells from the transplanted tissue of a donor initiate an immunologic attack on the cells and tissue of the recipient Complications of small bowel transplantation: * Most of the moality after bowel transplantation is due to sepsis ...
3
Acute rejection
Hyperacute rejection
GVHD
Chronic rejection
Surgery
null
6f9d620d-4afb-4eff-9ad7-893c8214f50e
single
Diagnosis of traumatic rupture of diaphragm is done by?
The most accurate evaluation of diaphragmatic rupture is by video assisted thoracoscopy or laparoscopy, the latter offering the advantage of allowing the surgeon to proceed to a repair and additional evaluation of the abdominal organs . Chest X ray with nasogastric tube maybe helpful CT scan and diagnostic peritoneal l...
1
A.Laparoscopy
B.Chest X ray
C.Diagnostic peritoneal lavage
D.CT scan
Surgery
Trauma
b8f0b1f8-6995-4a14-b9d3-e303f19f6cb4
single
Which of the following is used as an indicator for recent fecal contamination of water ?
Faecal streptococci regularly occur in faeces but in much smaller numbers than E.coli. Finding faecal streptococci in water is regarded as impoant confirmatory evidence of recent faecal pollution of water. Finding faecal Cl. perfringens in water in the absence of other organisms is regarded as impoant confirmatory evid...
4
E. Coli
Cornybacterium diptheriae
Pseudomonas
Streptococci
Social & Preventive Medicine
Environment and health
df21c703-a2cc-41d9-8500-7d86a1d6e3c9
single
Persistence of Moro&;s reflex is abnormal beyond the age of ________
Moro&;s reflex disappears by 3 - 6 months in normal infants. Persistence of the reflex after 6 months is abnormal and is common in children with MR without motor disturbance including Down's syndrome and in children with CP of the athetoid type. It is also sometimes observed in children with a severe brain malformation...
4
3rd month
4th month
5th month
6th month
Pediatrics
New born infants
c87b2b91-c8b0-4241-9f1d-af934d617381
single
Which of the following is recommended for culture sampling in Infective Endocarditis:
Answer is C (3 culture sets separated by at-least 1 hour over 24 hours) Three culture sets separated from one another by at-least I hour should he obtained over 24 hours. in the absence of prior antibiotic therapy three (2-bottled) culture sets separated from one another by at-least 1 hour should be obtained from diffe...
3
2 culture sets separated by at-least 1 hour over 24 hours
2 culture sets separated by at-least 2 hours over 24 hours
3 culture sets separated by at-least 1 hour over 24 hours
3 culture sets separated by at-least 2 hours over 24 hours
Medicine
null
a852993f-4404-4401-8b16-6463471d23c4
single
Fever in burnt patient is caused by:a) Due to hypermetabolismb) Toxin released by dead tissuec) Infectiond) Dead tissue products
Long: Principles and Practice of Pediatric Infectious Diseases, (3rd ed chapter 91) writes- "Diagnosis of infectious complications in a burn victim is challenging. Although fever and elevated peripheral white blood cell count with a left shift are usual indicators of infection, their positive predictive value for diagn...
2
a
ac
ad
b
Surgery
null
6ee3f046-ae61-4a64-a025-d6b8d8866ede
single
Alpha - wave in EEG is seen in -
C i.e. Awake
3
Sleep
REM sleep
Awake state
Mental work
Physiology
null
e262717b-3781-4629-bc7c-10c2e769f9e6
single
Which of the following drug causes flaccid paralysis of ascaris ?
null
3
Albendazole
Pyrantel pamoate
Piperazine
Ivermectin
Pharmacology
null
e1bfda0c-42a5-43b9-a8a8-d7fa8f8b7052
single
Long term complication (>10yr) renal transplantation is/are -
Chronic complications of renal transplant - Malignancy -most common lesions are cancers of skin, lips and carcinoma of cervix as well as lyhomas such as non Hodgkin lymphoma. Hypeension Hypercalcemia Anemia Chronic hepatitis -due to hepatitis B and C virus infection Ref:Harrison 20 th edition pg no 2131
2
Bacterial infection
Malignancy
Viral infection
Acute graft versus host reaction
Medicine
Kidney
d37a1f2f-5e20-46f2-b484-bf8d5b7e328b
single
Which among the following simple tests is used to measure/assess urethral hypermobility?
In Q tip test - A cotton swab is introduced into the urethra following which the patient is asked to perform valsalva manoeuver and the angle of urethra is assessed. An angle of excussion of > 300 from the horizontal indicates urethral hypermobility. Note:- Stress test can also be used to assess urethral hypermobility....
2
Office cystometry
Q tip test
Voiding diary
Postvoid residual urine
Gynaecology & Obstetrics
null
42d54ca9-718b-4acf-9b71-d1404926e9a0
single
Drug of choice for classical angina attack -
Ans. is 'c' i.e., GTN PHARMACOLQG1CALTREATMENT OF STABLE (CLASSICAL ANGINA)o For immediate pre-cxcrtional prophylaxis and acute attack1. Sublingual glyceral trinitrate (Drug of choice)o Acts by decreasing preload (LV filling pressure - i myocardial oxygen demand),o Also cause redistribution of blood flow to the ischemi...
3
CCBs
P-blocker
GTN
Prazocin
Pharmacology
D.O.C
64cf8c10-abe8-438a-8692-684829970343
single
In which of the following disease, Screening procedure increases the overall survival maximum?
Colonic cancer has highest 5-year survival rate post-screening. - This can be known by Kaplan meiyer survival analysis. - Screening of colonic cancer is done by colonoscopy. SCREENING TESTS OF OTHER OPTIONS: - Prostate cancer : Prostate specific antigen + DRE - Lung cancer : Chest x-ray - Ovarian cancer: transvaginal u...
3
Prostate cancer
Lung cancer
Colon cancer
Ovarian cancer
Social & Preventive Medicine
Definition and Concepts, Examples from NHPs
38326e13-b11a-4283-9daf-054a16af2fd4
multi
All are true about "lead time" except
Concept of Lead Time Lead time - Lead time is the period between early detection by Screening and diagnosis by other means later in life Lead time is the "Advantage gained by screening" Detection programs should be restricted to those conditions in which there is considerable time lag The benefits of the programme must...
4
Lead time is the period between early detection by Screening and diagnosis by other means later in life
Lead time is the advantage gained by screening
Detection programs should be restricted to those condition in which there is considerable time lag
None of above
Social & Preventive Medicine
Screening
cc4d97ae-cddb-478d-838d-20fe991422e9
multi
First line management of Menetrier's disease?
Menetrier's disease is example of protein losing enteropathy Premalignant condition Rugosities of stomach Foveolar cell hyperplasia (produce excess of mucin) Cerebriform appearance of stomach mucosa. Gastric fold are prominent in body and fundus & spares Antrum. In children's it is caused by CMV and in adult it is unkn...
1
Cetuximab
Octreotide
Subtotal Gastrectomy
Total Gastrectomy
Medicine
Inflammatory Bowel Disease
c366990e-6f0d-4d4d-9c87-c667db687001
single
Which type of eclampsia has the worst prognosis:
Prognosis in eclampsia long interval between onset of fit and commencement of treatment antepaum eclampsia with long delivery interval number of fits more than 10 coma in between fits temperature over 102 degree F with pulse rate above 120/min BP >200mmHg systolic oliguria with proteinuria non response to treatment jau...
1
Antepaum
Postpaum
Intrapaum
Imminent
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
2c25faac-73da-4798-bf67-df3e7841c148
single
Rat bite fever is caused by ?
null
2
Spirillum major
Spirillum minor
Yersinia
Leptospira
Microbiology
null
32196c22-40f5-4790-80d0-4eba71a9e8ad
single
Eales' disease is best treated with:
Ans. Steroids
2
Antitubercular drugs
Steroids
Antibiotic drops
Antibiotics systemically
Ophthalmology
null
24daa178-0397-4cb9-8f56-988817d8ed23
multi
Wernicke's encephalopathy is due to deficiency of -
Ans. is 'b' i.e., Thiamine Wernike's encephalopathyo This is caused by thiamine deficiency.o There are acute degenerative changes in thalamus, hypothalamus and mammillary bodies,o Signs are: confusion, ocular paresis and nystagmus, staggering gait and peripheral neuropathy.
2
Folic acid
Thiamine
Ascorbic acid
Pyridoxine
Psychiatry
Drug and Alcohol-Related Conditions
31b0e804-6488-491e-9ad4-3d640f5cb811
single
All help in assessing obesity except
null
4
Quetelet's Index
Ponderal Index
Corpulence Index
Sullivan Index
Social & Preventive Medicine
null
a24837a6-9db2-4e3a-9108-353b1b70a442
multi
Which amino acid has maximum tendency to bind phosphate ?
OH containing amino acid has maximum tendency to bind phosphate Eg.Tyrosine, Threonine and Serine.
1
Serine
Alanine
Phenylalanine
Tryptophan
Biochemistry
Basics of amino acids
11a5d2c8-09a9-4726-b91c-628e7f74e72f
single
Maximum visual impairment occurs in:
Nebular corneal opacity has maximal visual disability. Type of corneal opacities Nebular: Superficial layers involving upto superficiial stroma. It do more disability of vision owing to the irregular astigmatism. Macular: Upto mid stroma is involved as opacity Leucomatous: Full thickness stromal opacity. Adherent leuco...
3
Leukoma adherens at periphery
Centrocaecal leucoma
Nebular corneal opacity
Med peripheral Leucoma
Ophthalmology
Diseases of Cornea
369446dc-b1c5-41ad-9904-897892a63cdb
single
Basic defect in HbS is?
Basic defect in HbS is altered solubility. A molecule of hemoglobin S (HbS) contains two normal a globin chains and two mutant b globin chains- glutamate at position 6 is substituted with valine. This replaces the polar glutamine residue with a nonpolar valine. The replacement of glutamate by valine generates a sticky ...
2
Altered function
Altered solubility
Altered stability
Altered O2 binding capacity
Medicine
Sickle Cell Disease, G6PD deficiency and other Hemolytic Anemia
392e434d-3202-4d3c-837b-ed0c2a0c1351
single
Capsaicin acts on ______
Vanilloid receptor is a nociceptor. Capsaicin binds to Vanilloid receptor.
1
Vanilloid receptor
Capsaicoid receptor
AMPA receptor
NMDA receptor
Physiology
null
abdbb6c9-1a08-49ef-a6fc-ae1d0684cc6a
single
True about measles –a) Rash appear first on legb) Koplik spots are seen in retinac) Long term complication follows in form of SSPEd) Caused by RNA viruse) IP–IS 2–3 day
null
1
cd
bc
bd
ac
Pediatrics
null
6f1ec6fd-8b24-4d77-9946-b5589ae694a0
multi
Frequent blushing (“erethism”) is associated with : -
Mercury Mechanism of toxicity. Mercury reacts with sulfhydryl (SH) groups, resulting in enzyme inhibition and pathologic alteration of cellular membranes. Clinical presentation. Acute inhalation Severe chemical pneumonitis and noncardiogenic pulmonary edema. Acute gingivostomatitis may also occur. Chronic intoxication ...
1
Mercury
Lead
Phenolic acid
Carbolic acid
Unknown
null
5fa3529b-abd1-4c24-926b-ead59567267f
single
All of following are features of Ascher syndrome except:
null
2
Double upper lip
Tongue tie.
Blepharochalasis.
Non toxic thyroid enlargement.
Pathology
null
98c83b91-b5f5-489b-8504-3e2766066786
multi
Acetyl CoA cannot be conveed to:
Acetyl CoA is a staing material for Fatty Acid Synthesis, Cholesterol Synthesis & Ketone Body Synthesis (option a, c & d). But Acetyl CoA is never a substrate for Gluconeogenesis i.e. it can never form glucose (option b). Because Acetyl CoA can never be conveed back to Pyruvate as Link reaction or Pyruvate Dehydrogenas...
2
Fatty Acids
Glucose
Ketone Bodies
Cholesterol
Biochemistry
Fat and Carbohydrate interconversion
befeafe6-37cb-4a6f-ab10-8d39b66f1580
single
Bifurcation of Trachea is at the level of
Bifurcation of Trachea is at the level of Body of T6
1
Body of T6
Lower border of T6
Body of T4
Lower border of T4
Anatomy
null
c3150fd0-4863-4641-8f0a-dc9507531441
single
True about barbiturates ?
Ans. is ,a, i.e., Have steep dose response curve(Ref: Goodmen & Gillmen |2',h/e p. 471)Barbiturates depress all areas of CNS, but the reticular activating system is most sensitive.Barbiturates have steep dose response curve.Except For phenobarbitone in epiteliu andthiopentonein anaesthesia,barbituratesare used now'The ...
1
Have steep dose response curve
Have analgesic action
Are enzyme inhibitors
Acidification of urine is done in poisoning
Pharmacology
null
8b9a3254-d75b-43f1-b5bf-6290cca53322
multi
Tennis racket cells is seen in -
o Tumor cells of sarcoma botryoids are small and have oval nuclei, with small protrusions of cytoplasm from one end, so they resemble a tennis racket. REF: ROBBINS pathology 10th edition
1
Sarcoma botyroides
Vaginal adenocarcinoma
Leiomyoma uterus
Seminoma
Pathology
All India exam
30cfa0f4-3eef-48b9-b297-4fe69d45b9fd
single
Yellow color on the new WHO standard mid-upper arm circumference (MUAC) tape correlates to a MUAC of ________
Yellow color on the new WHO standard mid-upper arm circumference of (MUAC) tape correlates to a MUAC of 11.5 to 12.5 cm. Mid-Upper arm Circumference: Used in children between 6 to 60 months Measured between the acromion and olencranon process It is an age-dependent parameter (between 6-60 months) MUAC tape cut-offs Col...
2
10.5 to 11.5 cm
11.5 to 12.5 cm
12.5 to 13.5 cm
13.5 to 14.5 cm
Pediatrics
Nutrition
f4704a06-dae7-4278-8c3c-4fcc144104e9
single
The earliest identifiable cells of T-Cell lineage during maturation are
null
1
CD7+ Pro-T-Cells
CD4+ Pre-T-Cells
CD8+ Pro-T-Cells
CD8+ Pre-T-Cells
Microbiology
null
aa261275-1526-4a6c-9cbd-95dbba69b1fa
single
Mites are the vectors of the following disease except:
- Vector is an ahropod or inveebrate which can transmits an infection. - Mites are the vectors of: Scabies Scrub typhus Rickettsial pox Rickettsial Diseases Disease Cause Vector Reservoir Epidemic typhus R. Prowazeki Louse Man Endemic typhus R. Typhi flea Rodents Indian tick typhus R. conori Tick Rodents RMSF R. ricket...
4
Scabies
Scrub typhus
Rickettsial pox
Kyasanur forest disease
Social & Preventive Medicine
VBDs, Arboviral & Viral Infections, Surface Infections
90f30d52-e0f4-4148-844b-3d5ec5b441c4
multi
Protractor of scapula is?
Serratus anteriorREF: Gray's anatomy 39th ed p. 829, 830Movements of scapula:MovementMusclesElevationTrapezius and Levator scapularProtractionSerratous anterior and Pectoralis minorRetractionRhomboids and TrapeziusLateral rotationupper trapezius and lower serratousMedial rotationLevator scapulae , Rhomboids and Pectora...
1
Serratus anterior
Rhomboidis major
Deltoid
Pectoralis major
Anatomy
null
026f6c62-a3bc-4860-b28f-e2f75ad296aa
single
The positive inotropic effect of digitalis is due to inhibition of Na+/K+ ATPase pump in cardiac muscle cell membrane leading to:
null
1
Decreased activity of Na+/Ca++ exchanger causing decreased influx of sodium and decreased efflux of Ca++ in the sarcolemma
Decreased efflux of Na+ leading to less negative resting membrane potential and opening of voltage gated Ca++ channels on the T tubules
Increased intracellular Na+ causing increased efflux of Na+ and increased influx of Ca++ through Na+/Ca++ exchanger in the sarcolemma
Increased intracellular Na+ decreasing the activity of Ca++ pump in the sarcoplasmic reticulum
Pharmacology
null
f0d867d2-91a1-4918-bcad-1b1d504d19a6
single
Shagreen patch is a cha racteristic feature of -
Ans. is 'a' i.e., Tuberous Sclerosiso Shagreen Patch (connective tissue naevi) are roughened raised leathery lesions with an orange peel consistency that are typically seen in patients with Tuberous Sclerosis.
1
Tuberous sclerosis
Neurofibromatosis
Sturge weber syndrome
Von Hippei-Lindau syndrome
Medicine
C.N.S.
a8eb8efa-cbe1-4b1f-82ff-ec7ced51ce92
single
At some mass casualty ,patients with mandibular fractures are categorized under which of the following color code:
null
2
Red
Yellow
Green
Black.
Surgery
null
67963903-0463-4923-9f07-a4985e3afafc
single
Which of the following is the established biological therapy for Crohn's disease?
Tumor Necrosis Factor (TNF) is a key inflammatory cytokine and mediator of intestinal inflammation. The expression of TNF is increased in IBD. Infliximab is a chimeric human monoclonal antibody against TNF that is extremely effective in Crohn's disease. Recently adalimumab has also been approved for treatment of modera...
1
Anti TNF a antibody
IL - I antagonist
IL - 6 antagonist
IL - 8 antagonist
Medicine
Inflammatory Bowel Disease
f346a617-80a0-4928-bdf1-2cc1e4a11cab
single
Hardness of water is contributed by following salts except –
null
1
Calcium gluconate
Magnesium chloride
Calcium sulfate
Magnisum bicarbonate
Social & Preventive Medicine
null
d3dca0dc-37db-4bc4-992b-3b48154a456a
multi
Chronic granulomatous disease is
ref Harrison 18/e p 387 It is a congenital and not acquired leucocyte function defect CGD Overview. Chronic Granulomatous Disease (CGD) is an inherited primary immunodeficiency disease (PIDD) which increases the body's susceptibility to infections caused by ceain bacteria and fungi. Granulomas are masses of immune cell...
1
Associated with formation of multiple granulomas
A benign neoplastic process
A parasitic disease
Acquired leukocyte function defect
Anatomy
General anatomy
9aef4240-c534-4eb5-b386-66da740c4e07
single
False about ulcerative colitis
String sign is seen in chron's disease.
3
Continuous inflammation
Leadpipe appearance
String sign is seen
Crypt abscesses are typical
Medicine
null
637ee7f0-8551-44b6-a0d0-8cf5daaefe99
multi
Which poion of MHC1 complex forms the component of antigen presenting pa?
Antigen Presenting pa of MHCMHC 1/HLA I:Class 1 molecule consists of three domains of heavy alpha peptide chain (a1; a2; a3) which are non-covalently linked to smaller b2 microglobulin peptide.The distal domain (alpha 1 and alpha 2) of MHC 1 have highly variable amino acid sequences and are folded to form a cavity or g...
2
Between alpha 1 and beta 2 microglobulin
Distal pa of alpha chain
Proximal pa of alpha chain
Between alpha 2 and beta 2 microglobulin
Microbiology
All India exam
062cca06-4d7a-4524-99c3-d329b3217d87
single
A 50-year-old chronic alcoholic presents to the emergency room with 12 hours of severe abdominal pain. The pain radiates to the back and is associated with an urge to vomit. Physical examination discloses exquisite abdominal tenderness. Laboratory studies show elevated serum amylase. Which of following morphologic chan...
Fat necrosis. Saponification of fat derived from peripancreatic fat cells exposed to pancreatic enzymes is a typical feature of fat necrosis. Lipase, released from pancreatic acinar cells during an attack of acute pancreatitis, hydrolyzes fat into fatty acids and glycerol. Free fatty acids bind with calcium to form soa...
3
Coagulative necrosis
Caseous necrosis
Fat necrosis
Fibrinoid necrosis
Pathology
Irreversible cell Injury/Necrosis
64539050-ad52-4f92-b23e-c03e1ef85bf3
single
A patient develops hypoglycemia. He was on insulin and acarbose. For treatment of above what is to be given aEUR'
Glucose Hypoglycemic reactions are the most common complication of insulin therapy. It commonly result from: ? - Inadequate carbohydrate consumption - Unusual physical exeion - Too large dose of insulin Management of hypoglycemia All the manifestations of hypoglycemia are relieved by glucose administration. To increase...
1
>Glucose
> Maltose
> Sucrose
>Starch
Pharmacology
null
821a5026-0246-4fd8-b1e5-9f5cebf5b215
multi
A neonate presenting with heart failure on day 7 of life has this chest X-ray. What is the most probable diagnosis?
d. TGAChest X-ray showing 'egg on side' appearance in a neonate presenting with heart failure on day 7 of life has TGA (Transposition of great arteries)
4
TOF
VSD
TAPVC
TGA
Pediatrics
C.V.S.
2adc7fb6-4e92-4f82-81fc-8e2c311cfb76
single
Glucose may be synthesised from
Glycerol is release during the hydrolysis of triacylglycerols in adipose tissue and is delivered by the blood to the liver, where it is used in the synthesis of glucose by gluconeogenesis.
1
Glycerol
Adenine
Guanine
Palmitic acid
Biochemistry
null
2c8c3645-6799-4e27-bead-f3c4a4569e64
single
Mean hemoglobin of a sample of 100 pregnant women was found to be 10 mg% with a standard error of 1.0 mg%. The standard error of the estimate would he
0.1 Standard error of mean = Standard detion / lisample size = 1/ V100 = 1/10 = 0.1
2
0.01
0.1
1
10
Social & Preventive Medicine
null
509da9f1-b7f8-45c2-8642-5e9b952ac602
single
ICD-10 has how many chapters?
ANSWER: (C) 22REF: style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif; margin: 0 0 8pt 8px; text-indent: 0">Repeat from December 2009Remember Park 20th ed p. 46 has given only 21 chapters"ICD-10 was endorsed by the Forty-third World Health Assembly in May 1990 and came into use in WHO Memb...
3
5
12
22
32
Social & Preventive Medicine
Concept of Health and Disease
b6df9871-0f50-4da1-9d89-26c70340ed05
single
Magical thinking is seen in which type of personality disorder
* SCHIZOTYPAL PERSONALITY DISORDER * Ideas of reference (not delusions) * Odd beliefs and magical thinking * Unusual perceptual disturbances * Paranoid ideation and suspiciousness * Odd thinking and speech without coherence * SUPERSTITIONS/TELEPATHY * ODD DRESSING * ODD SPEECH LACK OF EMOTIONS Ref.KAplon and Sadock, sy...
1
schizotypal
borderline
narcisstic
histirionic
Psychiatry
Personality disorders
26d7e60f-53f7-4a23-b9c7-382a01a1955d
single
Middle meningeal artery is branch of -
null
1
l st part of maxillary artery
2 nd part of maxillary artery
3 rd part of maxillary artery
External carotid artery
Anatomy
null
5fb98a64-5c4f-4412-b105-0568e98cbb65
single
In monoclonal antibody production, monoclonal cells are differentiated from?
ANSWER: (C) Myeloma cell linesREF:Applications and engineering of monoclonal antibodies by David J. King page 17, A practical guide to monoclonal antibodies by J. Eryl Liddell, Anthony Cryer Page 69"A myeloma cell is classically defined as a neoplastic plasma cell in myelomatosis producing a structurally and electropho...
3
Sensitized B cells
Sensitized T cells
Myeloma cell lines
None of these
Biochemistry
Miscellaneous (Structure & Function of Proteins)
592253f4-48a2-4978-b14c-dfb46b390975
multi
Most important measure to prevent hospital infection -
Ans. is 'c' i.e.. Proper hand w ashing o There are following types of modes of transmission of hospital-acquired infections :Contact transmissionIt is the most common and most preventable means of transmission. It is divided into two types -Direct contact : It involves contact of body surface to body surface with a phy...
3
Use of antibiotics
Use of antiseptics
Proper hand washing
Formalin fumigation
Social & Preventive Medicine
Health Planning and Management
041baefd-4f83-43bf-b11f-887bbff9716d
single
Analysis of routine measurement aimed at detecting changes in the environment?
Monitoring is the performance and analysis of routine measurements aimed at detecting changes in the environment or health status of population.
3
Surveillance
Isolation
Monitoring
RCT
Social & Preventive Medicine
null
92d72313-c7c2-473c-b30e-174792bf24ac
single
Involution of the uterus is completed by :
6 weeks
1
6 weeks
8 weeks
12 weeks
16 weeks
Gynaecology & Obstetrics
null
ee5b9818-44b1-4a8d-a80d-ddb82a09e60b
single
Variant of Giant cell tumor is?
Chondroblastoma [Ref This is the best we could find, after long hours of search. "A chondroblastoma is a rare, usually benign, tumor of bone that accounts .for approximately I% of all bone tumors. In 1931, Cadman classified it as a chondromatous variant of giant cell tumors, when he described these lesions in the proxi...
4
Ossifying fibroma
Non ossifying fibroma
Osteosarcoma
Chondroblastoma
Surgery
null
db0b41ac-b005-4ca5-977d-9dbb35c234c8
single
Status epilepticus is managed best with the use of which of the following drugs ?
null
1
Intravenous diazepam
Intravenous phenytoin sodium
Intramuscular phenobarbitone
Rectal diazepam
Pharmacology
null
fad58253-cbca-4a86-9daf-edaed9cf6261
single
Gluten-sensitive enteropathy is most strongly associated with –
Almost all individuals with celiac disease share the major histocompatibility complex II HLA-DQ2 or HLA-DQ8. Gliadin is deamidated by the enzyme transglutaminase and deamidated gliadin peptides bind to DQ2 and DQ8. Recognition of these peptides by CD4+ T cells leads to secretion of IFN-γ, which damages the intestinal w...
1
HLA–DQ2
BLA–DR4
HLA–DQ3
Blood group B
Pediatrics
null
a5e586ee-5df7-433f-a872-94107e4f6d44
single
Species of Anopheles transmitting transmitting malaria is urban areas is
null
2
Culcifacies
Stephensi
Minimus
Fluviatilis
Social & Preventive Medicine
null
5d4af655-73f5-46c9-be6f-f0458690b2e8
multi
According to GOTTLIB diffused atrophy of alveolar bone is:
null
2
Periodontitis
Cementopathia
Periodontosis
Gingivosis
Dental
null
9d30fbcd-d1ef-4f53-bfb4-48bd7dd220a0
single
Biuret test is used for detection of:
Ans: a (Protein) Ref: Vasudevan 4th ed/p.23, 24. 34.Biuret reaction:-* Cupric ions chelate with peptide bonds of proteins in alkaline medium to produce a pink or violet colour. This needs a minimum of two peptide bonds and so individual amino acids and dipeptides will not answer this test.* Biuret reagent - CuS04, sodi...
1
Protein
Cholesterol
Steroid
Sugar
Biochemistry
Proteins and Amino Acids
249357a0-238b-4166-9367-4ac9d8655da8
single
False statement in collapsing glomerulopathy:
Ans. (c) There is noproliferation or hypertrophy of glomerular visceral epithelial cells(Ref: Robbins 9th/pg 920; 8th/pg 928)HIV-ASSOCIATED NEPHROPATHY (HIVAN) is characterized by collapse of entire glomerular tuft along with proliferation & hypertrophy of glomerular visceral epithelial cells Q
3
It is a morphologic variant of FSGS (focal segmental glomerulosclerosis)
Microscopically retraction and /or collapse of the entire glomerular tuft is seen
There is no proliferation or hypertrophy of glomerular visceral epithelial cells
It may be idiopathic or HIV associated nephropathy
Pathology
Kidney
de7afb04-010a-4af9-835e-6e4110ae4b0c
multi
Integrin connects actin to which macromolecule in ECM?
Ans. C. Fibronectin > LamininIntegrins localized in the plasma membrane are the major adhesion receptor connecting cells with components of the extracellular matrix. Integrins interact directly with laminin and mainly fibronectin present in the basal lamina and intracellularly contact actin through intermediate protein...
3
Vitronectin
Laminin
Fibronectin
Collagen
Pathology
Inflammation & Repair
a0eb68fd-ab7f-4f5a-820e-c795fab4c224
single
Mental retardation is diagnosed if. (Intelligence quotient) is less than
70
3
90
80
70
60
Psychiatry
null
2225fd58-8948-4443-91f2-5d33309285f6
single
Which of the following attains adult size before bih:
A i.e. Ear ossiclesAuditory (ear) ossicles attain full adult size at (or before) bihQ. Although mastoid antrum (air sinus) is well developed (& of adult size) at bih, but mastoid process & air cells develop later.
1
Ear ossicles
Maxilla
Mastoid
Mastoid
Anatomy
null
89b37685-6576-40eb-ba9b-0d4d54e393ea
single
Which organism causes toxin shock syndrome -
Ans. is 'c' i.e., Staphylococcus aureus Toxic shock syndromeo TSS is a potentially fatal multisystem disease characterized by sudden high fever, fainting, watery diarrhea, headache and muscle ache.o There are two types of TSS1. Staphylococcal TSSStaphylococcal TSS results from the elaboration of toxic shock syndrome to...
3
Pneumococcus
E. coli
Staphylococcus aureus
Enterococcus
Microbiology
Staphylococci
cfd61f88-8885-48fd-ae7f-6b76c44b54e1
single
RGD motifs are
null
2
Fibroblasts
Bone Sialoproteins & Osteopontin
Cementoblasts
Noncementum proteins
Dental
null
7baea7da-abd8-4cf4-8f9f-4ee5d549ce32
single
Contraindication for laryngeal mask airway is
LMA INDICATIONS : .Sho procedures where endotracheal tube is not necessary,Difficult airway , Cardiac arrest ,conduit for intubation, Contraindications Absolute :Complete Upper airway obstruction,Locked jaw relative : increased risk of aspiration like in full stomach, 2nd n 3rd trimester of pregnancy ,morbid obesity,Up...
2
Empty stomach
Hiatus hernia
Minor surgery
Young age
Anaesthesia
Anaesthetic equipments
f0251eb0-f3b6-4281-98c4-8494811a913d
single
Which of the following disease is also known as diabetic diarrhea:
Ans. C. Coeliac DiseaseAutoimmune disease having associated diabetesa. Chronic lymphocytic thyroiditis (Hashimoto)b. Celiac disease (Hence celiac disease is also known as diabetic diarrhea)c. Multiple endocrine deficiency syndrome
3
Whipple disease
Ulcerative colitis
Coeliac disease
Carcinoid Syndrome
Medicine
G.I.T.
526f9a25-6dcb-4856-8c09-63f966a421be
single
Nerve injured in inferior dislocation of shoulder is:
Reference: Apley's System of Orthopaedics and Fractures 9th edition, Page 743Explanation:Inferior dislocation of the shoulder or luxatio erectaIt is a rare type of dislocation caused by forceful hyper abduction. which causes the humerus to hitch on the acromion and the humeral head to be levered out of its socket and d...
1
Axillary nerve
Median nerve
Ulnar nerve
Radial nerve
Orthopaedics
Dislocation of Shoulder
0a207d7e-e9e0-47ff-8dde-e2883de204cf
single
A patient presents with history of episodic painful edema of face and larynx. Which of the following is likely to be deficient in this patient?
History of recurrent episodes of painful edema of face and larynx suggests a diagnosis of hereditary angioneurotic edema which is caused by deficiency of C1 esterase inhibitor. C1 esterase inhibitor (C1 INH) is an alpha-globulin, which controls the first stage of the classic complement pathway and inhibits thrombin, pl...
4
Properidin
Complement C3
Complement C5
CI Esterase Inhibitor
Medicine
null
5a2c00a9-ff88-436a-bad1-f7ef26552698
single
Which among the following causes 'thumb sign' on an X-ray lateral view of the neck?
Thumb sign is typically seen in acute epiglottitis due to swollen epiglottis. It is better appreciated in lateral view of neck. Normally, the epiglottis is quite thin in the anteroposterior (AP) dimension, resembling a little finger, whereas the abnormal, inflamed epiglottis appears shoer and has an increased AP dimens...
1
Acute epiglottitis
Acute laryngo trachea bronchitis
Acute tonsillitis
Acute laryngitis
ENT
null
5c37b8e4-4f3d-4f2f-9051-5f7196ec5e45
single
For sputum smear to come positive on ZN staining there should be minimum:-
Sputum smear microscopy for tubercle bacilli is positive when there are at least 10,000 organisms present per ml of sputum. ZN staining in RNTCP: Acid fast bacilli of TB; 'Rod shaped' with 'beaded appearance'. >10,000 bacilli per ml sputum must be present for a positive result.
4
100 bacilli per per ml sputum
1000 bacilli per ml sputum
2000 bacilli per ml sputum
10,000 bacilli per ml sputum
Social & Preventive Medicine
RNTCP
81824ec1-d6c6-43f6-89d0-e0f5d2b8c400
single
Most common cause of chronic kidney disease
Most common cause - Diabetes mellitus
1
Diabetes mellitus
Hypertension
PCKD
Hepatorenal Syndrome
Medicine
null
764da52a-c7ab-4311-baab-3c99bd006a71
single
Toad skin is seen in deficiency of vitamin ?
Ans. is 'a' i.e., A o Here, essential fatty acid has not been provided as an option. So, amongst the given options vitamin 'A' is the best answer.
1
A
B2
D
Biotin
Pediatrics
null
435e1b4f-71fb-43a5-8c02-6b8fde7de1b3
single
All are true about cystic fibrosis except?
Ans. (c) Fasting hyperglycemia is a feature of early disease(Ref: Refer Ans 7 & 10; Nelson 19th/pg 1996; Robbins 9th/pg 466-470; 8th/pg 465-470)Cystic fibrosis-related diabetes (CFRD)No diabetes is seen in CF patients younger than 10 yr while 40-50% show diabetes at >=20yr age;So diabetes is a late feature of CF, seen ...
3
Recurrent respiratory infections
Majority of males are infertile
Fasting hyperglycemia is a feature of early disease
Sweat chloride is >70 meq/1
Pathology
Disease of Infancy & Childhood
6dcd39f1-b9f0-427e-bf77-0010972b2c33
multi
A 24-year-old woman has clear evidence of bipolar disorder. An adequate trial of lithium therapy has proved unsuccessful. Which of the following drugs would be most reasonable for her psychiatrist to prescribe next?
A recent development in the pharmacologic treatment of affective disorders, especially bipolar disorder, has been the use of anticonvulsant drugs. The first to be tried, carbamazepine (Tegretol) often is the next line of treatment for bipolar disorder for persons unresponsive to lithium therapy. Carbamazepine has vario...
2
Chlorpromazine
Carbamazepine
Alprazolam
Amitriptyline
Psychiatry
null
e4ca7fa0-48a4-4f6e-ac64-fb561ca07a65
single
A 50 year old woman is presenting with bilateral solid ovarian tumors and has ascitis. Upper gastro-intestinal endoscopy reveals an ulcerative growth in pyloric region of stomach. The most likely diagnosis is:
The patient in this question having bilateral solid ovarian tumors with ulcerative growth in pyloric region of stomach is suffering from carcinoma of stomach with krukenberg's tumor. Krukenberg's tumors account for 30-40% of metastatic cancers to the ovaries, they arise in the ovarian stroma and has mucin filled signet...
4
Malignant ovarian tumor
Carcinoma in the small intestine
Carcinoma body uterus
Carcinoma stomach with Kurkenberg's tumor
Gynaecology & Obstetrics
null
79e9476e-eddb-4778-a50e-1a7f667b1080
multi
Which of the following is a less useful diagnostic procedure in a case of acute haematemesis?
Ans. Barium meal
1
Barium meal
Endoscopy
Gastric content aspiration
Angiography
Radiology
null
93b252a4-86ee-4d56-abe4-6258bf372cec
single
What is the acceptable angel of reduction for tibial fracture
Trafton&;s recommendation and strive to achieve less than 5 degrees of varus-valgus angulation, less than 10 degrees of anteroposterior angulation, less than 10 degrees of rotation, and less than 15 mm of shoening.
1
5
1
15
20
Orthopaedics
All India exam
8e82f8b6-b5da-4b37-ae8b-0afa1ec214a2
single
Reservoir of Tetanus infection is
Soil is the Reservoir of: Tetanus Anthrox Coccidiomycosis Mycetoma
2
Man
Soil
Pig
Plants
Social & Preventive Medicine
null
caf3ad71-4fcf-4846-8aa0-22dc167cd724
single
Substance obtained from lipoxygenase pathway and shows chemotaxis to neutrophils is
Leukotrienes B4 obtained during LOX pathway shows chemotaxis and leukocyte adhesion. Arachidonic Acid Metabolites and their actions in Inflammation:-
1
LT B4
LX A4
Prostacyclin
Thromboxane A2
Pathology
null
4974d6da-cb62-4ffc-b35f-1147b4412ae5
single
Methylene blue reduction test is done for estimating?
Ans. is 'd' i.e., Bacterial activity in milk
4
Fat content of milk
Sugar content of milk
Protein content of milk
Bacterial activity in milk
Social & Preventive Medicine
null
99d40741-cd96-4616-949f-66ac1fc8f226
single
Commando's operation is for
It is en-bloc removal ,which includes wide excision of primary tumour with hemimandibulectomy and neck block dissection,examples : it is done usually in carcinoma of tongue or floor of the mouth ;it is a composite resection of primary tumour ,mandible and radical neck dissection(RND) SRB,5th,451.
4
Mandible
Radical mastectomy
Leg amputation
Oral cancer
Surgery
Head and neck
46315b77-4eef-4508-9d9e-260c89ade01b
single
Digoxin toxicity is aggrevated by
Hypokalemia is usually observed with chronic toxicity or in patients taking diuretics; it reduces the rate of Na+/K+ ATPase pump turnover and exacerbates pump inhibition due to digitalis. Hyperkalemia is the usual electrolyte abnormality precipitated by digoxin toxicity, primarily in the acute setting Refer kDT 6/e p49...
1
Hypokalemia
Hyperkalemia
Hypermagnesimaia
Hypocalcemia
Pharmacology
Cardiovascular system
149616ec-c147-4dae-8ae4-7b466b7717cd
single
What causes secretory diarrhea ?
null
4
Cholera
Laxatives
Excess phenolphthalein intake
All of the above
Medicine
null
2a8bfc24-f033-49da-876e-2b3e27441913
multi
A pt. with psoriasis was started on systemic steroids. After stopping t/t pt. developed generalized pustules all over his body, the most likely cause is:
Ans. is 'b' i.e Pustular Psoriasis Pustular Psoriasis - It is generalized pustule formation which can complicate asArthritis*Exfoliation*Constitutional Symptoms *Conditions which precipitate pustular psoriasisSteroids *Salicylates*Iodides *
2
Drug induced reactions
Pustular Psoriasis
Bacterial infection
Septicemia
Skin
Psoriasis
a3412221-d343-4004-b5af-74af4e532ea0
multi
MC commensal gut flora in adult -
In the human intestines, Anaerobes out number aerobic bacteria a thousand fold Among anaerobes Bacteroides are in predominant number in human gut flora.
2
Lactobacillus
Bacteroides
E. coli
Klebsiella
Microbiology
null
a30b7734-81f4-4eca-8d9b-ae55d6630ccc
single
Which serum is used for testing streptococcal pyrogenic toxin?
Ans. is 'a' i.e., Convalescent human serum Tests related to pyrogenic toxin (erythrogenic /Dick toxin) of streptococcus There were two historical tests which were used : i) Dick test : Intradermal Injection of toxin in a child produces erythematous reaction if he/she is susceptible to scarlet fever. ii) Schultz scharlt...
1
Convalescent human serum
Serum from patient of acute scarlet fever
Horse serum
None of the above
Microbiology
null
405f0c2a-a799-49ef-a616-6b20e799ab93
multi
Which one of the following medical disorders leads to delayed foetal lung maturity -
Ans. is 'b' i.e., Diabetes o Maternal diabetes predisposes to HMD.
2
Hea disease
Diabetes
Thalassemia minor
Epilepsy
Pediatrics
null
481d31d7-91a1-4cea-95f3-edb130a47e0d
single
Base of hea is at the level of which veebrae ?
Ans. is'c' i.e., T5 - T8
3
C4 - C7
C7 - T2
T5 - T8
T9 - T12
Anatomy
null
6cbcd51a-8a9f-469f-80dc-9b86a52f8182
single