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Which of the following statements about stavudine is accurate ?
null
2
Bone marrow suppression is dose limiting
It causes marked neurotoxicity
It inhibits HIV protease
It is a non–nucleoside reverse transcriptase inhibitor
Pharmacology
null
45b67012-ff8d-4806-98f0-a2fec72c3505
multi
What is the glomerular filtration rate (GFR)?
null
4
25 mL/min
50 mL/min
100 mL/min
125 mL/min
Physiology
null
350cabf9-502b-428f-94b0-5b5a7015359a
single
Sabin-Feldman dye test is used for diagnosis of: March 2005, 2009 and September 2007
Ans. D: Toxoplasma The most common method of laboratory diagnosis of toxoplasma gondii is by serology like Sabin-Feldman dye test, indirect immunofluorescence, indirect haemagglutination, complement fixation and ELISA. Sabin-Feldman dye test is based on the specific inhibition by antibody of the staining of the trophoz...
4
Cryptosporidium
Babesia
Pneumocystis
Toxoplasma
Microbiology
null
dfffbc42-51c5-482b-ab55-a65d3cbe38ea
single
Which of these is a conservative mutator
Conserved mutation means altered AA has same properties of original AA. e.g. glutamic acid to aspartic acid (both acidic) or alanine to leucine (both aliphatic).
3
Glutamic acid-glutamine
Histidine-glycine
Alanine-leucine
Arginine-aspartic acid
Biochemistry
null
e742c910-be61-421c-b8e9-e599e091aa98
single
The X-ray appearance of a CBD stone on cholangiography is:
Ans. Meniscus appearance
1
Meniscus appearance
Eccentric occlusion
Sudden cut off
Smooth tapering
Radiology
null
d65e2265-c92c-48db-952f-dda05bc3cb09
single
Cells present in cerebral coex are all, except:
Bipolar cells
1
Bipolar cells
Purkinje cells
Golgi cells
Granule cells
Anatomy
null
4b5a1182-7cae-4389-8d6e-223fc4c35704
multi
McNaughten's rule relates to?
Ans. c (Criminal responsibility). (Ref. Parikh, FMT, 5th ed., 538).The following are the tests for determining criminal responsibility of Insane.1. Me. Naughten Rule: "An accused person is not legally responsible, if it is clearly proved, that at the time of committing the crime, he was suffering from such a defect of ...
3
Inquest
Professional secrecy
Criminal responsibility of insane
Medical negligence
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
c3d9a8ee-cc55-4343-8f70-67cb1b444cdf
single
Abdominal visceral pain is transmitted by:
null
4
A-fibers
C-fibers
Parasympathetic fibers
Sympathetic fibers
Physiology
null
a9cdec97-0d0b-47d4-bed2-45334ee33986
single
Which of the following is a phytosterol?
Sterols are molecules with the cyclopentano-perhydro-phenanthrene (CPP) nucleus Sitosterol Plant (phyto) sterol Ergosterol Fungal (myco) sterol Cholesterol Animal (zoo) sterol Plant sterols (sitosterol) | absorption of cholesterol Sitosterolemia Autosomal recessive disorder Defects in either ABCG5 or ABCG8 | Plant ster...
1
Sitosterol
Cholesterol
Ergosterol
Calcitriol
Biochemistry
Chemistry of Lipids
bc9f7f85-860e-442f-9540-4ab88d22feb7
single
patient with stab injury to the lower chest presented with low pulses and BP improved after giving IV fluids Chest Xroy showed clear lung fluids Next step in the management
abdominal injury=Stable- CECT/ Unstable - eFAST ref : bailey and love 27th ed
4
chest tube inseion
CECT abdomen
CECTchest
e fast
Surgery
All India exam
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multi
The minimum number of polyps necessary for a diagnosis of Familial Adenomatous Polyposis (FAP) is:
Ans. (d) 100(Ref: Robbins 9th/pg 809; 8th/pg 820-824)Classic FAP -At least 100 polyps are necessary for a diagnosis QAttenuated FAP-lower number of adenomatous polyps (around 30)
4
5
10
50
100
Pathology
G.I.T.
27521073-b3a3-4600-8569-168b880e850c
single
Nutrient and oxygen reach the chondrocytes across perichondrium by -
Answer- B. Diffusionchondrocytes within the matrix must receive nutrients and oxygen by diffusion from vessels that lie outside the cailage.
2
Capillaries
Diffusion
Along neurons
Active transpo
Surgery
null
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single
In which of the following corneal ulcers signs are more than symptoms:
Ans. (a) Fungal corneal ulcerRef: A.K. Khurana 6th ed. H06, Khurana 4th ed./100* Fungal corneal ulcer aka fungal keratitis is most commonly caused by Aspergillus fusarium. Patient in this condition presents with history of trauma with vegetative matter.* Symptoms shown by patients here are milder than signs. Signs are ...
1
Fungal corneal ulcer
Bacterial corneal ulcer
Viral corneal ulcer
Herpetic corneal ulcer
Ophthalmology
Inflammations of the Cornea
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A 14 yr old boy with abnormal movements. MRI shows involvement of bilateral striatum, thalami, puns, centrum semiovale and asymmetrical diffuse white matter involvement. What could be the possible diagnosis?
Ans. Wilson's disease
1
Wilson's disease
Hallevordon spatz disease
Nigrostriatal degeneration
Parkinsonism
Radiology
null
f2bee3fa-8e60-4d9d-bdb8-5d31788bff20
multi
Epiglottis is derived from ?
Ans. is 'b' i.e., 4th archAll cailages of larynx (except arytenoid) are derived from 4th arch - epiglottis, cricoid, thyroid, corniculate and conciform.Arytenoid is derived from 6" arch.See explanation-8 of session-1.NoteDevelopment of laryngeal cailages is controversial. According to some textbooks, all laryngeal cail...
2
3rdeg arch
4th arch
5th arch
6th arch
Anatomy
null
afbb5795-23fe-4531-8262-5e7e248ef4ae
single
Which of the following is a psychiatric emergency
Suicide is a psychiatric emergency. Suicide is preventable and can be identified early using a scale called as SAD PERSONS scale. Other impoant psychiatric emergencies are neuroleptic malignant syndrome Serotonin syndrome Agitated patient Ref.Kaplon and sadock, synopsis of psychiatry, 11 th edition, pg no. 763
2
Capgras syndrome
Suicide
Acute schizophrenia
Cocaine use
Psychiatry
Treatment in psychiatry
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single
True about spinal cord
*Upto 3rd month of intrauterine life, spinal cord extends throughout the entire length of veebral canal.*Thereafter, the veebral column grows faster than the Spinal cord and the terminal end of Spinal cord gradually shifts to a higher level.*At bih, it ends at level of L3 veebra and in adults, it ends at level of lower...
4
In adults spinal cord ends at lower border of L1 veebra
In newborn may extend up to L3
Cauda equina extends from lumbar veebra to coccyx
All of the above
Anatomy
Brain
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multi
Saturated salt solution concentrates eggs of all, except-
Helminth eggs floating in saturated salt solution: Hell FATE Hell-Helminth,H.nana F-Feilised eggs of Ascaris A-Ancylostoma duodenale T-Trichuris trichiura E-Enterobius vermicularis
1
Unfeilized egg of ascaris
Trichuris
Hymenolepsis nana
Enterobius vermicularis
Microbiology
parasitology
ee5d815b-8335-40c2-9290-905ee1cd2421
multi
In acute convulsions due to toxicity to local anaesthetic most important step in immediate management is –
Treatment of local anesthetic toxicity First step is to ensure adequate oxygenation, by face mask or intubation. LA infusion should be stopped immediately. Anticonvulsants like benzodiazepines (midazolanz) and barbiturates (thiopentone) are the drugs of choice for seizure control. Propofol can also be used. For hypote...
1
Secure airway
Adrenaline
IV short acting barbiturate
Diazepam IV
Anaesthesia
null
f36980b3-8e80-41d1-8409-8b902ffcdfce
multi
Eugene Bleuler's four 'A' of schizophrenia are all except-
null
3
Autism
Affect
Anhedonia
Association
Psychiatry
null
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multi
ABO antigen are found in all except ?
Ans. is 'c' i.e., CSF ABO antigen can be demenstrated in all body fluids except CSF"_________ Reddy. They are detected in almost all tissues, but not found in - Nerve tissue Epithelium Skin appendages Bone Cailage
3
Saliva
Sweat
CSF
Gastric juice
Forensic Medicine
null
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multi
CSF pressure depends primarily upon?
Ans. B. Rate of absorptionCSF pressure depends primarily upon Rate of absorption because the rate of the formation is fairly constant.
2
Rate of formation from choroid plexus
Rate of absorption
Cerebral blood flow
Blood pressure
Physiology
Nervous System
40b45dd5-4c82-4f83-a79e-84b84412ea24
single
Third pa of veebral aery is related to which marked area in the following diagram
Marked structures are as follows: A: Posterior arch of atlas; B: Foramen transversarium; C: Anterior arch; D: Superior aicular facet. Veebral aery has 4 pas: V1 - Preforaminal (from subclan aery to transverse foramen of C6) V2 - Foraminal (through the transverse foramina of C6 to C2) V3 - Extradural (from the transvers...
1
A
B
C
D
Anatomy
Head and neck blood supply and scalp
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single
Regarding upper GI bleed-true statement is
Ref. Sabiston Textbook of Surgery. Pg. 1142   GI Bleeding Most common cause of GI Bleed is Non variceal bleeding (80%) Upper GI bleed is defined bleeding arising from esophagus ,stomach ,or duodenum . Rockall and Baylor scoring for predicatabilty of rebleeding and mortality 1st line management includes IV Fluids + blo...
4
Most common cause is variceal bleeding
It is bleeding up to ampulla of Vater
MC management is endoscopic banding
Rockall scoring is used for risk stratification
Unknown
null
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multi
Which one of the following is not a non-metastatic complication of malignancies -
<img src=" /> Image ref - Harrison internal medicine 20e p541
2
Cushing's syndrome
Elevated ALP
Cerebellar digeneration
Polymyositis
Medicine
Oncology
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single
In the overview of Beta oxidation of fatty acids, A denotes:
null
3
Enoyl CoA
Acyl CoA
Acetyl CoA
Malonyl CoA
Biochemistry
null
7e856325-68b8-4809-acd3-f02ca294da46
single
A 68-year-old diabetic male presents with persistent ear discharge with fever and headache. He complained of pain out of propoion. On examination, granulations and tenderness are observed on the floor of the external auditory canal along with facial nerve palsy. He is not responding to antibiotics. What is the most pro...
Ans. a. Malignant otitis externa Presence of a painful lesion in the external ear with the evidence of granulation tissue and associated cranial nerve palsies (VII nerve) in a diabetic (or immunocompromised) patient suggest a diagnosis of malignant otitis externa.
1
Malignant otitis externa
Malignant disease of middle ear
Malignant disease of nasopharynx
Chronic otitis externa
ENT
null
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single
Polyamine like putrescine is derived from:
Ans. (b) Ornithine* Polyamines like spermine, spermidine and putrescine metabolite are produced from L-ornithine by action of ODC (ornithine decarboxylase).* S-Adenosylmethionine, the methyl group donor for many biosynthetic processes, also participates directly in spermine and spermidine biosynthesis.
2
Arginine
Ornithine
Yohimibine
Arginosuccine
Biochemistry
Proteins and Amino Acids
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single
Which is the most common side effect of inhaled beclomethasone dipropionate:
Most of the side effects of steroids are mainly hoarseness, oropharyngeal candidiasis, decreased growth in children with adrenal suppression. • The plausible explanation is that since these drugs are inhaled, they avoid the first pass metabolism that orally administered steroids undergo and hence have a preponderance t...
1
Oropharyngeal candidiasis
Pneumonia
Atrophic rhinitis
Pituitary adrenal suppression
Pharmacology
null
4420be68-9847-44e1-bdf6-5f3f77dd5bc2
single
Lung granuloma with necrosis are seen in -a) PANb) TBc) Histoplasmosisd) Cryptococcosise) Wegener's granulomatosis
Granuloma with necrosis TB    → caseous necrosis Syphilis    → caseous necrosis Coccidiodomycosis   →  caseous necrosis Histoplasmosis   →  caseous necrosis Wegner’s granulomatosis – Non-caseous necrosis
1
bce
bc
acd
ace
Pathology
null
42565e78-1a10-4ea7-8be5-17ab9071578e
single
With regards to imaging of primary extra nodal lymphomas, in which of the following sites does extra nodal Hodgkin's disease most commonly occur:
At presentation, Hodgkin disease is usually supra diaphragmatic which means thymus is involved due to contiguous spread from one nodal group to the next along the lymphatic pathways. Hence thymus is involved before spleen and other abdominal organs. Thyroid gland is rarely involved in Hodgkin lymphoma.
2
Spleen
Thymus
Thyroid
Small bowel
Medicine
Lymphoma and Plasma cell disorder
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multi
All of the following are true about Type I DM, Except:
Answer is A (Family history is present in 90% of cases): A strong family history (.90%) is a feature of type II DM and not type I DM. Family history may he present in only about 15% cases of type I DM.
1
Family history is present in 90% of cases
Antibodies against 3 ells
Prone to Diabetic Ketoacidosis (DKA)
Insulin is required for management of DKA
Medicine
null
649baa25-3650-4357-a291-0369e55db8d6
multi
Rubella is caused by
Family Togaviridae includes Genus Alphavirus --> Western Equine Encephalitis (WEE) , Eastern Equine Encephalitis (EEE) , Venezuelan Equine Encephalitis (VEE) and Chikungunya fever (CGF) Genus Rubivirus --> Rubella Rubella: Aka German measles. I.P - 14-21 days Source : cases Mode of transmission : Respiratory / air drop...
3
Ohomyxovirus
Paramyxovirus
Toga virus
Arbovirus group B
Social & Preventive Medicine
NEET 2019
679de40e-f99a-4754-977c-709e449f77af
single
True about legionella:
Ans. is. 'b' i. e., There is no man to man transmission
2
Most common mode of transmission is aerosol inhalation
There is no man to man transmission
Prolonged carrier are common
All are true
Microbiology
null
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multi
Cardiac motion is visible with trans vaginal imaging when the embryo length has reached
Cardiac motion is visible when embryo reaches length of 5mm.
1
5 mm
10 mm
15 mm
20 mm
Gynaecology & Obstetrics
null
89d575df-be3e-45e7-9cd8-ffca62b43d45
single
Oil and grease are sterilised by-(
Ans. is 'a' i.e., Hot air oven
1
Hot air oven
Autoclaving
Filtration
Irradiation
Microbiology
null
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single
Common organisms causinh sinusitis:
according to scott Brown 7/e,p 1441 M/C Organism causing sinusitis in adults is also Streptococcus pneumoniae followed by H.influenza. In childreb M/C is streptococcus pnuemonia followef by both H.influenza and moraxella catarrhalis.
3
pseudomonas
Moraxella catarrhalis
Streptococcus pneumoniae
H.influenza
ENT
Nose and paranasal sinuses
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single
Liquid medium for tuberculosis -
Ans. is 'd' i.e., MGIT o Mycobacterial growth indicator tube (MGIT) is an automated liquid culture method. It contains 7 ml of modified Middle brook 7 H9 Broth base.Media for tubercular bacilliSolid mediaLiquid mediao L.J. mediumo Dorset mediumo Petragnini mediumo Loeffer mediumo Tarshis mediumo Duboso Middle brook'so ...
4
LJ medium
Dorset medium
Loeffler's medium
MGIT
Microbiology
Mycobacteria
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Prolactin is synthesized in -
Ans. is 'a' i.e., Pituitary
1
Pituitary
Hypothalamus
Pineal gland
Thalamus
Physiology
Endocrinology metabolism
470275c6-8f47-42e3-b7c3-7eaf9c1706ee
single
Uveitis is associated most commonly with:
C i.e. Pauciaicular JRA Anterior Uveitis is more common in pauciaicular seronegative (i.e. RA factor negative) IRA Q than in polyaicular JRA or systemic JRA. Seropositivity for ANA factor in pauciaicular JRA predisposes to uveitis. Most of the times the term "Seronegative" or "Seropositive" is used in relation to RA fa...
3
Rheumatoid ahritis
Systemic JRA
Pauciaicular JRA
Polyaicular JRA
Ophthalmology
null
40e079b4-fa2d-40fd-9b98-a7f9aa9138b9
single
All of the following can aggravate Myasthenia gravis except :
null
1
Azathioprine
d–Tubocurarine
Tetracycline
Aminoglycoside
Pharmacology
null
cdb2a04d-4082-4da9-b62c-4a537e701d23
multi
The Endotoxin from the gram-negative organism is -
Endotoxins heat stable lipopolysaccharides which form an integral pa of the cell wall of gram-negative bacteria. Their toxicity depends on the lipid component. They are released only by the disintegration of the cell wall. They cannot be toxoided. They are poor antigens and their toxicity is not completely neutralized ...
4
Polysaccharide
Glycoprotein
Lipoprotein
Lipopolysaccharide
Microbiology
general microbiology
63ab01b7-a1c5-4512-827c-3f4c35f4480e
single
In Marfan's aortic aneurysm occurs in -
null
1
Ascending aorta
Arch of aorta
Descending aorta
Abdominal aorta
Medicine
null
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single
Treatment of choice of penicilline resistant gonococcol infection is -
null
1
Spectinomycin
Ceftriaxone
Penicillin
Ceflazidime
Medicine
null
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single
Nerve supply of pinna
A. i.e. Greater auricular nerve; B. i.e. Auriculotemporal nerve; C. i.e. Occipital nerve
4
Greater auricular nerve
Auriculotemporal nerve
Occipital nerve
All
Anatomy
null
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multi
A person has episodes of vomiting 6 hrs after consuming milk. Organism responsible for this may be: March 2009
Ans. B: Bacillus cereus and D: Staphylococcus Incubation period of food poisoning due to: Clostridium perfringenes: 6-24 hours Bacillus cereus-It produces atleast 2 distinct enterotoxins. One, the emetic form with a sho incubation period (1-6 hours) characterized by predominantly upper gastrointestinal tract symptoms, ...
2
Clostridium perfringenes
Bacillus cereus
Salmonella typhi
Staphylococcus
Social & Preventive Medicine
null
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single
What is the most likely diagnosis of this penile lesion found in a 54-year-old man with lymphadenopathy and weight loss?
Answer A. Squamous-cell carcinomaSquamous-cell carcinoma is the correct answer. Human papillomavirus (HPV) is a common risk factor for squamous-cell carcinoma of the penis, as is the case here. HPV can also cause cervical cancer in women. The presence of metastasis to the inguinal lymph nodes is a poor prognostic facto...
1
Squamous-cell carcinoma
Syphilis
Extramammary Paget disease
Condyloma acuminatum
Medicine
Miscellaneous
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single
All are true about Giant cell arteritis except -
It is the most common form of systemic vasculitis in adults, is an acute and chronic, often granulomatous, inflammation of arteries of large to small size. It affects principally the arteries in the head-especially the temporal arteries — but also the vertebral and ophthalmic arteries and the aorta, where it may cause ...
3
Involves large to small sized arteries
Granulomatous inflammation
Most commonly involved artery is abdominal aorta
Segmental nature of the involvement
Pathology
null
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multi
The infratentorial dura is supplied by branches of the
The tentorium cerebelli is a tent-shaped fold of dura mater, forming the roof of the posterior cranial fossa.It separates the cerebellum from the occipital lobes of the cerebrum and broadly divides the cranial cavity into supratentorial and infratentorial compaments. The infratentorial compament, in other words, is the...
1
Upper cervical spinal nerves and the vagus nerve
Accessory and upper cervical nerve
Only upper cervical nerves
Only vagus nerve
Anatomy
Head and neck
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single
TRUE about folic acid and vitamin B12 is all, except-
Ans. is 'b' i.e., Recommended daily allowances for Folic acid is 1000 micro grams
2
Both are required for DNA synthesis
Recommended daily allowances for Folic acid is 1000 micro grams
Vegetarians have vitamin B 12 deficit
Deficiency of both causes megaloblastic anaemia
Social & Preventive Medicine
null
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multi
The most predictive and dangerous side effect of propranolol that makes it to be avoided in known patient of COPD is induction of -
null
2
Respiratory failure
Acute asthmatic attack
Glaucoma
Pleural effusion
Medicine
null
a9f6009b-e031-4a85-ba7d-bae00a25872c
single
Which of the following fungi is/are difficult to isolate culture -
Malassezia furfur does not grow on regular sabouraud's medium. It requires complex media to grow M. furfur is a lipid-dependent fungus and 1% emulsified olive oil is added to sabouraud medium for its cultivation Two media are now widely employed for all Malassezia species. Dixon medium Modified Dixon medium
4
Candida
Dermatophytes
Cryptococcus
Malassezia furfur
Microbiology
null
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Asplenic pt-more susceptible to-
Ans. is 'd' i.e., Pneumococcus o Most common infection after splenectomy is by - streptococcus pneumoniae ( -50-90% of cases )o Other common bacteria! infections:Haemophilous influenzae type BMeningiococcusGroup A streptococcuso Common Protozoan inf. after splenectomy are:BabesiaEhrlichiaMalariao No increased risk of v...
4
Staphylococcus
Pseudomonas
Neisseria
Pneumococcus
Surgery
Consequences and Complications of Splenectomy
737ca460-3caa-4150-a6cc-d8d8cdafcf67
single
Which of the following antiepileptic drugs can cause hirsutism in a 30 year old woman?
ADVERSE EFFECT OF PHENYTOIN: H - Hirsutism , Hyperophy of gums O - Osteomalacia T - Teratogenicity M - Megaloblastic anemia A - Ataxia and nystagmus L - Lymphadenopathy I - Inhibits insulin release (hyperglycemia) K - Vitamin K deficiency A - Arrhythmias
1
Phenytoin
Carbamazepine
Valproate
Ethosuximide
Pharmacology
Epilepsy
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single
Polycythemia Vera is characterized by all, EXCEPT:
null
1
Bleeding
Increased viscosity of blood
Splenomegaly
None of the above
Medicine
null
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multi
The most frequent cause of recurrent genital ulceration in a sexually active male is
PCR testing of genital ulcers now clearly implicates genital herpes as the most common cause of genital ulceration in developing countries Genital herpes is a common sexually transmitted disease (STD) that any sexually active person can get. Most people with the virus don't have symptoms. Even without signs of the dise...
1
Herpes-genitalis
Aphthous ulcer
Syphilis
Chancroid
Dental
Sexually transmitted diseases
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With chronic use in seizure state, the adverse effects of this drug include coarsening of facial features,hirsutism, gingival hyperplasia and osteomalacia:
null
4
Carbomazepine
Ethosuximide
Gabapentin
Phenytoin
Pharmacology
null
b5aa9c45-051b-467e-835a-b2fb6fea9005
single
Which of the following is an impoant marker for myocardial infarction?
LDH is a tetrameric enzyme consisting of two monomers types: H (for hea) and M (for muscle) that combine to yield 5 LDH isoenzymes: HHHH(I1), HHHM(I2), HHMM(I3), HMMM(I4), MMMM(15). Tissue injury releases a characteristic pattern of LDH isoenzymes that can be separated by electrophoresis.The blood test most commonly us...
4
LDH
CK-MB
Troponins
All of the above
Biochemistry
null
5a41675a-fdcd-499b-b4a9-7ac72fc6a6b1
multi
DOC for Levodopa induced vomiting is?
Domperidone crosses blood brain barrier poorly. The anti-emetic action is exeed mainly through CTZ which is not protected by blood brain barrier. Because of poor entry into CNS, it does not block the therapeutic effect of Levodopa in Parkinsonism, but counteracts its dose limiting emetic action. It is a D2 receptor ant...
4
Metoclopramide
Ondansetron
Doxylamine
Domperidone
Pharmacology
Sedative-Hypnotics and Parkinsonism
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single
A 78-year-old man with advanced renal disease has the ECG shown in Figure below (lead II). What is the diagnosis?
No atrial activity is detected. The ventricular rate is slightly irregular. Beat number 4 is a ventricular premature contraction. The T waves are tall and markedly peaked. This type of T wave is characteristic of hyperkalemia, as is absence of visible atrial activity.The potassium level was 8.2mmol/L.
1
hyperkalemia
hypercalcemia
hypernatremia
pericarditis
Medicine
C.V.S.
62b825ee-10b5-4196-a508-aa1d59f07d8c
single
All are the features of absence seizures except -
null
3
Usually seen in childhood
3-Hz spike wave in EEG
Postictal confusion
Precipitation by hyperventilation
Medicine
null
31729532-703c-4f7b-8ac2-765bd23f8668
multi
All are components of basement membrane except -
fibronectin -a major component of the interstitial ECM laminin -a major constituent of basement membrane The GBM consists of collagen (mostly type IV), laminin, fibronectin, entactin(nidogen), and several other glycoproteins. rhodopsin is one of the visual pigment in the eye, present in rods, helps in dim light vision ...
4
Nidogen
Laminin
Entactin
Rhodopsin
Pathology
General pathology
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multi
Type 'A' personality is characterized by all except,
Ans. is 'd' i.e. Mood fluctuations Type A personality disorder also known as type A behaviour pattern is a set of characteristic that includes beingImpatientExcessively time consciousInsecure about one's statusHighly competitiveHostile and aggressiveIncapable of relaxationType A individuals are often highly achieving w...
4
Hostility
Time pressure
Competitiveness
Mood fluctuations
Psychiatry
Disorders of Adult Personality
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multi
'Gastrocolic reflex' is related with?
Mass peristalsis Gastrocolic reflex: Facilitates appearance of mass movements after a meal. Ex., For gastrocolic reflex - Seen in early infancy.
2
GERD
Mass peristalsis
Duodenual reflex
Rectoanal refelx
Physiology
null
4090f8ed-606f-4080-bd3b-a0951aa35d82
single
Gastric motility is increased in:
Acid in duodenum
1
Acid in duodenum
Tryptophan in duodenum
Distension of stomach
Fatty food in stomach
Physiology
null
d795f77e-52f6-4b0e-9a9f-bdd755255735
single
Which of the following anticholinesterase is derived from natural source
Refer kDT 6/e p 102 Physostigmine is a highly toxic parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor. It occurs naturally in the Calabar bean and the Manchineel tree. The chemical was synthesized for the first time in 1935 by Percy Lavon Julian and Josef Pikl.
1
Physostigmine
Pyridostigmine
Neostigmine
Tacrine
Pharmacology
Autonomic nervous system
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single
Dark ground microscopy is used for detection of -
null
1
Spirochetes
Chlamydia
Fungi
Virus
Microbiology
null
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single
An 18-year-old man is seen in the clinic for routine assessment. He reports no active symptoms, there is no past medical history and he is not taking any medications. He mentions that his brother has a "low blood count" that is hereditary but does not recall the name of the disorder.His physical examination is entirely...
An increased amount of HbF or HbA2 is present in patients with beta-thalassemia. As the hemoglobin beta-chains are decreased in beta-thalassemia, the excess alpha-chains combine with gamma-and delta-chains to make HbF and HbA2, respectively. Increased osmotic fragility of red cells is a feature hereditary spherocytosis...
1
an increased amount of fetal hemoglobin (HbF) or hemoglobin A2 (HbA2)
increased osmotic fragility of the red cells
absent bone marrow iron
increased macroglobulin's in the serum
Medicine
Blood
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multi
Subclinical infection is common in-
Inapparent infection is one where the clinical effects are not apparent. the term subclinical infection is often used as synonym. Japanese encephalitis is a serious illness and there have been outbreaks in india.the disesa is abrupt in onset with fever,headache and vomiting,followed by signs of encephalitis. In epidemi...
4
Measles
Mumps
Rubella
Japanese encephalitis
Microbiology
general microbiology
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single
Flaccid bullae lesions with oral mucosal lesions. The finding in immunoflourescence is –
Flaccid bullae with involvement of oral mucosa suggest the diagnosis of pemphigus vulgaris. In pamphigus, there is intercellular deposition of IgG in fish-net pattern.
1
Fish net IgG in epidermis
Linear IgG in DEJ
Granular IgA in dermal papillae
Linear IgA in reticular dermis
Dental
null
ba12ec5f-858f-4492-aba0-240ebddf921b
single
Mode of action of fluoxetine -
Fluoxetine is a selective serotonin reuptake inhibitor.
3
GABA agonist
GABA antagonist
Inhibit uptake of 5-HT
Increase uptake of 5-HT
Psychiatry
null
01c2c5e0-3ebf-4287-ac86-4b3ffdbec128
single
Giant&;a&;wave in JVP is seen in-
in Tricuspid stenosis The jugular veins are distended, and in patients with sinus rhythm there may be giant a waves. The v waves are less conspicuous, and because tricuspid obstruction impedes RA emptying during diastole, there is a slow y descent. In patients with sinus rhythm there may be prominent presystolic pulsat...
4
Junctional rhyth
Tricuspid regulation
Complete hea block
Tricuspid stenosis
Medicine
C.V.S
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single
Receptor mediated endocytosis requires:
Clathrin-mediated endocytosis occurs at membrane indentations where the protein clathrin accumulates. Clathrin molecules have the shape of triskelions, with three "legs" radiating from a central hub. At the neck of the vesicle, the GTP-binding protein dynamin is involved, either directly or indirectly, in pinching off ...
4
Clatharin
Dynamin
Actin
All of the above
Physiology
Cell Membrane and transpo protiens
817c99d4-55fc-446b-ad8d-b367128b210c
multi
Which of the following vitamin has a role in the regulation of gene expression and tissue differentiation?
Retinoic Acid has a Role in the Regulation of Gene Expression and Tissue Differentiation. A major role of vitamin A is in the control of cell differentiation and turnover. All-trans-retinoic acid and 9-cis-retinoic acid regulate growth, development, and tissue differentiation Like the thyroid and steroid hormones and v...
1
Vitamin A
Vitamin C
Vitamin K
Vitamin B12
Biochemistry
vitamins
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single
In Jorgenson technique drugs given by IV routes are:
Jorgenson technique includes intravenous administration of opioids. The drugs used in Jorgenson technique are: a) Pentobarbitol b) Mepiridine c) Scopalamine (Hyoscine) d) Pethidine, etc.
4
Pentobarbitol
Scopalamine
Pethidine
All of the above
Surgery
null
3e320c00-393d-47eb-a7ac-3eeee0236fa7
multi
Sperm attains motility in:
Although initially only slightly motile, spermatozoa obtains full motility in the epididymis Development of the spermSpermatogenesis is the process of spermatagonia (diploid) mature into spermatozoa (haploid).Spermioogenesis is a pa of spermatogenesis where round spermatids mature into the mature spermatozoa form.Sperm...
4
Vas deferens
Rete testis
Seminal vesicle
Epididymis
Anatomy
null
8b24e102-6972-472a-ab51-6eced94758e6
single
Which of the following vitamin deficiencies is uncommon in celiac disease
Ans. is `d' i.e., Vitamin B12 'Vitamin B is absorbed from the body in the end pa of small intestine (terminal ileum). Because this pa of the bowel is seldom damaged - by celiac disease, Vitamin Bit deficiency is not common in this condition'
4
Vitamin D
Folic Acid
Vitamin A
Vitamin B12
Medicine
null
5f90dad9-a2bc-483e-9de1-34263af11a68
single
Inherited cancer syndrome include all except?
Ans. is 'b' i.e., Neurofibroma Neurofibromatosis (multiple neurofibroma) is inherited cancer syndrome, not isolated neurofibroma.
2
Retinoblastom
Neurofibroma
Xeroderma pigmentosa
Familial polyposis coli
Pathology
null
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multi
The fluoride concentration of human milk ranges from:
Fluoride concentration of human milk ranges from 5-10 µg/L.  These levels are found in nursing mothers living both in non-fluoridated and fluoridated areas.  Cow's milk contains 30-60 µg/L of fluoride. Essentials of preventive and community dentistry  Soben Peter 5th edition
1
5-10 µg/L
2-8 µg/L
3-12 µg/L
2-10 µg/L
Dental
null
883d25ef-9eb3-4fd2-8ca4-b17c37214f3b
single
A new born child developed respiratory depression In neonatal ward. Which of the following drug is the cause –
null
1
Opioids
Barbiturates
Diazepam
Propofol
Pediatrics
null
2d201db9-ef3b-4e2c-bf23-4ef78b65e0be
single
Pernicious anemia associated with ?
Ans. is 'a' i.e., Gastric Pathology Anemias of Vitamin B12 Deficiency: Pernicious Anemia Pernicious anemia is a specific form of megaloblastic anemia caused by an autoimmune gastritis that impairs the production of intrinsic factor, which is required fir vitamin B12 uptake from the gut. Histologically, there is a chron...
1
Gastric pathology
Renal pathology
Esophageal pathology
Oral pathology
Pathology
null
182b4632-1826-4cf5-aef0-a8362baaeb08
single
Which is the shortest acting mydriatic ?
Atropine is longest acting (5-6 days) whereas tropicamide is the shortest acting (15-60 min) mydriatic.
2
Atropine
Tropicamide
Cyclopentolate
Homatropine
Pharmacology
null
b9217df5-0ab0-4afa-ba86-7842daf2f4e2
single
Commonest site of the vermiform appendix is
null
1
Retrocaecal
Subcaecal
Pre-ilial
Post-ilial
Medicine
null
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single
A 40-yr-female progressive dyspnea from 1 yr. She also has b/I bibasilar end inspiratory crepitation. The true statement is:
The patient is having interstitial inflammatory lung disease with progressive dyspnea & bilateral basal end-inspiratory crackles.9% of ILD can be associated with connective tissue disorders like, SLE, Rheumatoid arthritis, Ankylosing spondylitis, Systemic sclerosis, Sjogren's syndrome, polymyositis-dermatomyositis. In...
1
May be assocated with connective tissue disease
Residual volume (upword arrow) ed
(upward arrow) Total lung capacity (TLC)
null
Medicine
null
ea1c50ee-de02-4518-b727-b5680f586d0f
multi
The most common position adopted for surgical procedures is
.Lithotomy position used for all perineal surgeries like for fissure, piles, fistula, and APR. ref:SRB&;s manual of surgery,ed 3,pg no 913
3
Trendelenburg position
Lithotomy position
Supine position
Prone position
Surgery
Urology
43ef2f8d-f6c0-473c-9d73-cac0c1ba2e00
single
The MOST common organism isolated in emphysematous pyelonephritis is:
Emphysematous pyelonephritis is a form of acute necrotizing pyelonephritis secondary to a gas-producing bacteria (E coli in 66% of cases and Klebsiella in 26%). It is commonly seen in patients with poorly controlled diabetes (over 90% of cases) or in patients with upper urinary tract obstruction. The diagnosis is made ...
1
E. coli
Proteus
Pseudomonas
Klebsiella
Microbiology
null
cae5abcc-253c-43e2-9d29-f231e46007d8
single
Definitive sign of scurvy in X-ray ?
Definitive sign of scurvy in X-rays of long bones is the white line of Frenkel,an irregular thickened line at the metaphyses representing calcified cailage at the zone ofcalcification.Other characteristic findings are ground glass appearance with thinning of coex and a zone of rarefaction under the white line of metaph...
3
Ringed epiphysis
Ground glass appearance
White line in metaphysis
Thin coex
Pediatrics
Metabolic disorders
fee2bf81-e87a-4744-a10e-5a7773be445d
single
SI unit for measuring Blood Pressure is :
C i.e. KPa
3
Torr
mmHg
kPa
Barr
Physiology
null
49624d7b-9f46-49c8-91f4-880651e71920
single
Drug(s) included in the treatment of visceral leismaniasis is/are all except -
<p> Pentamidine is not a drug for treatment of leishmaniasis Sodium stibogluconate, Amphotericine B, Miltefosine are dug of choice for visceral leishmaniasis. Park&;s textbook of preventive and social medicine,K.Park,23rd edition,page no:307. <\p>
2
Sodium stibogluconate
Pentamidine
Miltefosine
Liposomal amphtericine B
Social & Preventive Medicine
Communicable diseases
61ff3b46-cce3-4968-90a2-1709ecd1448d
multi
As a junior resident , you are managing a patient of COVID-19 . When will you stop the treatment in COVID 19 patient ?
When will you stop the treatment in COVID 19 patient ? Two consecutive negative PCR repos atleast 24 hours apa WITH Clinico-radiological improvement
2
Two consecutive negative PCR repos atleast 48 hours apa with Clinico-radiological improvement
2 consecutive negative PCR repos atleast 24 hours apa with Clinico-radiological improvement
3 consecutive negative PCR repos atleast 48 hours apa with Clinico-radiological improvement
3 consecutive negative PCR repos atleast 24 hours apa with Clinico-radiological improvement
Medicine
viral infection
717245ef-a3e3-4dac-b69e-0c09992a78f8
single
False negative hydrostatic test in live fetus is for
False negative hydrostatic test can be seen in :- 1. Diseases e.g. : acute edema, pneumonia, Congenital syphilis. 2. Atelectasis False positive hydrostatic test can be seen in :- 1. Presence of putrified gases. 2. Aificial inflation.
1
Atelectasis
Aicial respiration
Emphysema
Putrefaction
Forensic Medicine
Impotency, Virginity, pregnancy & aboion
77349c7e-23a9-45ff-be88-8ec13efb8922
multi
30 To -60 degree axis detion indicates:
Answer is A (Left Axis Detion): Detion of the cardiac axis more negative than -30 (Between -30 to -90) indicates Left Axis Detion.
1
Left Axis Detion
Right Axis Detion
Extreme Right Axis Detion
Normal Cardiac Axis
Medicine
null
4559c602-720e-4659-a495-5d6ca01e5c82
single
The characteristics of polio vaccine are all except -
Park&;s Textbook of Preventive and Social Medicine 23rd edition Page no: 206, 207 After 3 doses of OPV, the mean propoion of infants with detectable serum neutralizing antibody level was only 73% for type1, 90% for type 2 and 70% for type 3 polio virus
2
Maintenance of cold chain
100% immunisation
Killed vaccine is effective in India
5 doses of OPV given
Social & Preventive Medicine
Communicable diseases
8762fc01-ac59-4152-a6cd-b77a632f2bdc
multi
Commonest site for ischemic colitis is -
Ans is 'b' ie. Splenic flexure "Although splenic flexure is the most common site of ischemic colitis, any segment of colon may be affected. The rectum is relatively spared because of its rich collateral circulation."
2
Hepatic flexure
Splenic flexure
Descending colon
Ascending colon
Surgery
null
c7b5890e-a124-4891-8232-0d8d9c8da6e1
single
A patient having multiple Gall stones and shows 8 mm dilation and 4 stones in CBD, best treatment modalities are -a) Cholecystectomy with choledocholithotomy at same settingb) ESWLc) Cholecystectomy and wait for ERCPd) Sphincterotomy and then cholecystectomye) Cholecystectomy and after 14 days sphincterotomy done
Management of suspected or proven CBD stones associated with gall bladder stones For gallstones - laparoscopic cholecystectomy is the procedure of choice. For CBD stones two things can be done : 1) If the surgeon is experienced in laparoscopic techniques of CBD stone removal then both cholecystectomy and choledochol...
4
b
c
ac
ad
Surgery
null
e1cb1aa1-b8d1-49e7-a1bf-28a4060bb2db
multi
All of the following are moality indicators except?
Disability adjusted life years (DALY) is a disability rate. Moality Indicators are: Crude death rate Life expectancy Infant moality rate Propoion moality rate Case fatality rate Years of potential life lost (YPLL)
1
Disability adjusted life years (DALY)
Years of potential life lost (YPLL)
Life Expectancy
Case fatality rate
Social & Preventive Medicine
Disease Causation, Measurements, Milestones
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multi
Modifiable risk factors for hypertension is ?
Ans. is 'd' i.e., Obesity Risk factors for hypertensionModifiableNon - modifiableo Obesity'o Salt intakeo Saturated fato Dietary fibreo Alcohol intakeo Physical activity'o Environmental stresso Socio-economic statuso Ageo Sexo Genetic factorso Ethnicity
4
Genetic factors
Age
Sex
Obesity
Social & Preventive Medicine
Non-Communicable Diseases
78325813-54dc-497a-983b-bfc61f1c7a82
single
which of the following is true regarding competitive reversible antagonism
COMPETITIVE Reversible ANTAGONISM 1.Same receptor by forming Weak bonds 2. Maximal response is concentration dependent 3.The effect of antagonist can be overcome by increasing the concentration of agonist 4. Parallel rightward shift of DRC COMPETITIVE Irreversible ANTAGONISM 1. Have affinity for the same receptor sites...
3
potency increases
Km decreases
efficacy and Vmax no change
ED50 decreases
Pharmacology
All India exam
3dcd483d-0bcc-421f-9e99-ac0445131194
multi
True about Pendred syndrome is:
Ans. D. All of the abovePendred syndrome, a disorder of the pendrin gene, is associated with decreased intracellular transport of iodine and deafness. Transient congenital hypothyroidism may occur following transplacental passage of TSH receptor blocking anti bodies iodine exposure and treatment with drugs like amiodar...
4
Diffuse colloid goitre
Mental retardation
Bilateral sensory neural deafness
All of the above
Pediatrics
Genetics And Genetic Disorders
1c0c9192-04d6-4417-8ff9-43808e0a7a0f
multi
Golden period for treatment of open wounds is .....hours -
Ans. is 'a' i.e., 4
1
4
6
12
24
Surgery
null
d560d60b-f2ae-4d77-8e9b-9f3ffde845b2
single