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All of the following statements about keloids are true except:
Keloids and hypertrophic scars both occur aftet injuries operations. Hypertrophic scars remain confined to the original injury site and usually regress spontaneously. By contrast, keloids extend beyond the original wound and rarely regress. Keloids contain abnormally large amounts of soluble collagen and water. Keloids...
3
A keloid does not regress spontaneously
A keloid extends beyond the boundaries of the original wound.
Keloids or hypertrophic scars are best managed by excision and careful reapproximation of the wound
Keloid tissue contains an abnormally large amount of collagen
Unknown
null
eb9eda71-854d-4c0a-8a77-ab6022574be1
multi
Which one of the following DOES NOT lie within the posterior mediastinum?
Phrenic nerve lies in the superior mediastinum and not in the posterior mediastinum. All other choices lies within the posterior mediastinum.Posterior mediastinum: The region containing anatomic structures deep to the pericardial sac, including the thoracic poion of the descending aoa, the azygos system of veins, the t...
1
Phrenic nerve
Vagus nerve
Esophagus
Thoracic aoa
Anatomy
null
e4e063b6-ad0d-45d3-bd17-01c596fb4877
single
Biochemical etiology of Alzheimer's disease relates it to :
A i.e. Acetyl choline
1
Acetylcholine
GABA
Serotinin
Dopamine
Psychiatry
null
756a6c5e-1347-422c-a4e3-b3f5d04390c9
single
The most frequent cause of scalded skin syndrome is ?
Ans. is 'a' i.e., Staphylococci Toxin mediated illness caused by staphylococcus aureus are : Toxic shock syndrome Food poisoning Styphylococcus scalded-skin syndrome Toxic epidermal necrolysis
1
Staphylococci
Pneumococci
Enterococci
Meningococci
Microbiology
null
add05d3e-80de-470f-99aa-74b9b994b4c7
single
Granuloma formation is not seen in?
Ans, is 'a' i.e. Asthma List of important granulomatous diseases* Important causes of immune granuloma arei) Bacterial infections TB, leprosy, syphilis, brucellosis, salmonellosis, Q-fever, cat scratch disease, yersinia.ii) Fungus & parasites Histoplasma, blastomycosis, coccidioidomycosis, schistosomiasis, trichiniasis...
1
Asthma
Hodgkins disease
Sarcoidosis
Q-Fever
Pathology
Inflammation & Repair
5ed9419a-95f1-432e-8cce-0507e43f5ec3
single
Pringle's Maneuver is used to stop the bleeding from
Pringle maneuver is soft clamping hepatic artery and portal vein at the point of entry. It is done for liver trauma patients.
1
Liver
Spleen
Kidneys
Flail chest
Surgery
null
10eb7b46-7593-4873-8b02-197ad01a240b
single
Which of the following does not require a lumbar puncture in children?
b. HL(Ref: Ghai 8/e 616-617)Discussing the options one by one,a. ALLCNS infiltration is common in ALL, so diagnostic lumbar puncture & CSF cytopathology to look for blasts is done; LP is also done to administer intrathecal methotrexateb. HLUsually Lumbar puncture is not requiredc. NHLHematogenous spread may cause CNS s...
2
ALL
HL
NHL
AML
Pediatrics
Childhood Tumors
878f4591-11ce-404a-b41d-29e490ff249e
multi
The most important cells in type I hypersensitivity -
null
2
Macrophages
Mast cells
Neutrophils
Lymphocytes
Microbiology
null
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single
Mechanism of action of duloxetine is ?
Ans. C. Selective inhibition of both serotonin and nor-epinephrine reuptakeDuloxetine, is a drug classified under serotonin-norepinephrine reuptake inhibitors (sNRJs).At lower doses it is more prominent serotonin reuptake inhibitor.Whereas at higher doses it is more prominent inhibitor of nor-epinephrine reuptake.It ha...
3
Selective Inhibition of serotonin reuptake
Selective inhibition of nor-epinephrine reuptake
Selective inhibition of both serotonin and nor-epinephrine reuptake
None of the above
Psychiatry
null
8e77ac52-ed10-401b-87dc-8346ee07b56d
multi
Epinephrine added to a solution of lignocaine for a peripheral nerve block will:
(Ref: K DT 6/e p354) Adrenaline and felypressin are the vasoconstrictors that are added to LA solution. By causing vasoconstriction, these drugs - decrease the systemic absorption resulting in less CNS adverse effects (decreased chances of seizures). Prolong the stay of drug at the site of action resulting in the incre...
2
Increase risk of convulsions
Increase the duration of action of the local anesthetic
Both (a) and (b)
None of these
Pharmacology
Other topics and Adverse effects
9fab8fb7-ecb4-4d37-9551-8c299ded7b54
multi
Conduct disorder in a child manifests with
A i.e. Disregard for rights of others; B i.e. Doesn't care for authority; C i.e. Backward in studies C.D. is characterized by a persistent & significant pattern of conduct in which the basic rights of others are violated or rules of society are not followedQ. Clinical features include: Frequent lying Stealing or robber...
4
Disregard for right of others
Doesn't care for authority
Backward in studies
All
Psychiatry
null
6d5e2bef-7cb3-4702-b89c-e773aa9b1227
multi
Roughly what percentage of patient with metastatic epithelial ovarian cancer will be benefited by treatment with an alkylating agent :
50 to 74 percent
3
Less than 10 percent
25 to 49 percent
50 to 74 percent
75 to 89 percent
Gynaecology & Obstetrics
null
5a30c0bd-409e-4693-a76c-7faf6508b37e
single
Which of the following drugs is preferred for long term treatment of severe anxiety disorder with intermittent panic attacks ?
null
4
Phenothiazine
Azapirone
β blocker
Selective serotonin reuptake inhibitor
Pharmacology
null
00ef7e1f-df20-4d00-bd90-2f10dd34b60c
single
Immunisation for HBV is which level of prevention
Specific protection for HBV, comes under primary prevention.
2
Primordial
Primary
Secondary
Tertiary
Social & Preventive Medicine
null
6ae67738-11f1-45fa-be44-637ef5e7cefd
single
The upper lip is derived from
The upper lip is formed by the fusion of two maxillary prominences with the two medial nasal prominences Ref : Langman's Medical Embryology 14e pg 295,298.
2
Maxillary prominence and mandibular prominence
Maxillary prominence and medial nasal prominence
Maxillary prominence and lateral nasal prominence
Mandibular prominence and medial nasal prominence
Anatomy
General anatomy
87f84d04-bb0d-49d7-a780-27fe106e7ee9
single
IUGR babies on delivery are called?
Small for date REF: Williams Obstetrics 22nd edition Chapter 36 Low bihweight defines neonates who are born too small, and preterm or premature bih are the terms used to define neonates who are born too early. With respect to gestational age, a newborn may be preterm, term, or postterm. With respect to size, a newborn ...
2
Growth retarded
Small for date
Low Bih Weight
Preterm
Gynaecology & Obstetrics
null
96519e75-62e9-4809-a49c-682aecfa60e0
multi
Anterior fontanelle ossifies by: March 2013 (b, f)
Ans. C i.e. 18 months Its pathological if anterior fontanelle fails to ossify by 24 months
3
6 months
12 months
18 months
24 months
Pediatrics
null
221651c6-6cc5-40ea-af60-e730e30eb64e
single
Impression material that do not harden by chemical reaction:
Reversible materials, such as agar and impression compound, soften upon heating and solidify slightly above body temperature with no chemical change taking place.
2
Zinc oxide eugenol
Impression compound
Alginate
Plaster of paris
Dental
null
12af7d93-fe69-48cc-b67f-1db826820cd5
single
Which of the following is true about Coronary blood flow?
Ans. (b) Maximum during diastoleRef.: Ganong 25th ed. 1611* The Flow in coronary arteries occurs in the sub- endocardial portion of the left ventricle only during diastole, although the force is sufficiently dissipated in the more superficial portions of the left ventricular myocardium to permit some flow in this regio...
2
Stable throughout the cardiac cycle
Maximum during diastole
Maximum during systole
Regulated by sympathetic vasodilatory activity
Physiology
Circulation: Coronary Circulation and Ischemic Heart Disease
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Radiotherapy after mastectomy would not be required in which of the following case scenarios of breast ca:
Ans is 'b' i.e. Metastasis "Radiotherapy to the chest wall after mastectomy is indicated in selected patients in whom the risks of local recurrence are high. This includes patients with large tumours and those with large numbers of positive nodes or extensive lymphovascular invasion." - Bailey and Love For distant meta...
2
Large tumor
Metastasis
Axillary nodal involvement
Positive margins
Surgery
null
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Who introduced the vaccination for smallpox?
"Edward Jenner introduced vaccination for smallpox with cowpox virus in 1798" Ref: Ananthanarayanan, 7/e, Page 5-7
1
Edward Jenner
Louis Pasteur
Mathieu Orfila
John snow
Microbiology
null
017b2aea-a3ea-484c-8ffa-7093007cfec4
multi
Which of the following step of glycolysis is inhibited by iodoacetate?
null
3
Phosphoenol Pyruvate to Pyruvate
2 Phosphoglycerate to Phosphoenol Pyruvate
Glyceradehyde 3 Phosphate to 1,3 bisphosphoglycerate
3 Phosphoglycerate to 2 Phosphoglycerate
Biochemistry
null
1d0e46f6-7442-4523-bfec-823d2f819d79
multi
A lady with prolapsed uterus after Fothergill's repair will complain of following except:
In Fothergill's repair ceroidical amputation is done which leads to Incompetent os Habitual abortion (second-trimester abortion and not first trimester, as incompetent os, leads to second-trimester abortion) Preterm deliveries Premature rupture of membranes                                                              ...
1
First trimester abortion
Cervical dystocia
Premature labour
Premature rupture of membrane
Gynaecology & Obstetrics
null
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multi
Hampton hump is seen in:
Ans. (c) Pulmonary embolismRef: Harrison 19th ed. /1633HAMPTON HUMP is a radiologic sign which consists of a shallow wedge-shaped opacity in the periphery of the lung with its base against the pleural surface.
3
Pulmonary TB
Bronchogenic carcinoma
Pulmonary embolism
Pulmonary hemorrhage
Radiology
Imaging of Interstitial Lung Disease
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Which of the following has autosomal inheritance-
Ans. is 'b' i.e., Marfan syndrome o Marfan syndrome is an autosomal disorder (autosomal dominant).o Hemophilia is X-linked recessive.o CHD and gout have multifactorial inheritence.
2
Hemophilia
Marfan syndrome
CHD
Gout
Pathology
Mendelian Disorders: Single-Gene Defects
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single
A 65-yrs-old man has broad-based ataxia, loss of pain, and temperature sensation in the lower extremities with lightening pains. His pupils accommodate but do not constrict with direct light stimulation. The spinal fluid would be expected to exhibit.
This patient has tabes dorsalis, which is a form of neurosyphilis where the spirochete attacks the posterior columns and the dorsal roots of the spinal cord. This attack produces: 1. Impaired joint position sense (proprioception), leading to a broad-based ataxia and a positive Roan berg test 2. Loss of pain and vibrati...
3
Encapsulated yeast cells
A neutrophil-dominant cell count
A positive VDRL
Toxoplasma cysts
Medicine
null
2c26ddb7-1c9d-4d4a-bc91-485b437a4d6c
single
A CKD patient had to undergo dialysis. His Hb was 5.2 gm% so two blood transfusions were to be given. First bag was completed in 2 hours. Second was started and midway he developed shortness of breath, hypertension. Vitals: BP 180/120 mm Hg and pulse rate 110/min. What is the cause?
Ans. B Transfusion related circulatory overloadRef: Harrison 20th ed. pg. 814* This CKD patient has developed severe anemia which is a compensated heart failure state. The patient was given first unit of blood in two hours instead of standard four hours and he is already in compensated heart failure.* The acute decompe...
2
Allergy
Transfusion related circulatory overload
TRALI
FNHTR
Physiology
Heart, Circulation, and Blood
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multi
Epiretinal membrane is seen in -
Ans. is 'a' i.e. Posterior vitreous detachment o Epiretinal membrane is a disease of the eye in response to changes in the vitreous humor or more rarely, diabetes. It is also called macular pucker.o Sometimes, as a result of immune system response to protect the retina, cells converge in the macular area as the vitreou...
1
Posterior vitreous detachment
Optic neuritis
Papilloedema
Glaucomatous optic atrophy
Ophthalmology
Retinal Detachment
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single
Histamine stimulate the secretion of:
According to Davenport theory, hydrochloric acid secretion is an active process in the canaliculi of parietal cells in gastric glands, utilising the energy derived from oxidation of glucose. Factors stimulating the secretion of HCl: Gastrin Histamine Vagal stimulation Factors inhibiting the secretion of HCl: Secreti...
3
Gastrin by stomach
Pancreatic enzymes
HCl by stomach
Amylase by salivary gland
Physiology
null
37e52695-d6ea-4661-bd99-21869e5ae362
single
Least common site involved in osteoahritis is
Ans. is 'd' i.e., Distal carpophalangeal joint In the hand the joints specifically involved are ? Distal interphalangeal join& (of paicular impoance is the point that this joint is not involved in rheumatoid ahritis). Proximal interphalangeal join& First carpometacarpal jointsQ Remember these two impoant features of jo...
4
Hip joint
Knee joint
Carpometacarpal joint of thumb
Distal carpophalangeal joint
Medicine
null
57f3bd84-835b-4fd4-8a50-961c15dd5d34
single
Which of the following anti-retroviral drugs does not cause peripheral neuropathy?
Ans. A. Lamivudinea. Peripheral neuropathy (PN) is a well-known adverse effect of NRTIs, mainly Zalcitabine, didanosine and stavudine. Several studies have shown that PN is more frequent when didanosine and stavudine are used in combinationb. Emtricitabine and lamivudine are safest NRTIs. These are not associated with ...
1
Lamivudine
Stavudine
Didanosine
Zalcitabine
Pharmacology
Anti Microbial
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single
Radiation exposure during which period of Pregnancy is highly lethal
Lethality risk is highest during the pre-implantation period - up to 10 days post conception. This is likely due to blastomere destruction caused by chromosomal damage.
2
During fetal cardiac development
Before implantation
During closure of proximal neural tube
None of the above
Gynaecology & Obstetrics
null
29edec47-19e7-4b0a-a485-34caf2f64ea4
multi
Which of the following finding is MOST compatible with sudden rhythm disturbance and cessation of the action of the hea?
The light lungs are more compatible with sudden rhythm disturbance and cessation of action of hea. The heavier lung (450 - 500 gms or more) indicates cessation of respiration with continuation of the hea beat for several minutes. Ref: Textbook of Forensic Medicine and Toxicology by Narayan Reddy, Edition 21, Page - 115...
1
Light lung ( 300 gm)
Heavy lung (450 - 500 gm)
Both
null
Forensic Medicine
null
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multi
C1 esterase inhibitor deficiency causes -
Ans. is 'b' i.e., Hereditary angioneurotic edema o Hereditary angioneurotic edema is due to Ci inhibitor (Cj esterase inhibitor) deficiency.Complement Deficiencies and Associated DiseasesComponentAssociated DiseasesCLASSIC PATHWAYClq,Clr,ClS,C4C2Cl inhibitorImmune-complex syndromes, "pyogenic infections"Immune-complex ...
2
Neisseria infection
Hereditary angioneurotic edema
Hemolytic disease
Hemolytic uremic syndrome
Microbiology
Immunology
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single
The following information is available about the body fluid volumes of a normal male: total body water, 40 liters; intracellular water, 25 liters; plasma water, 4 liters. The volume of the interstitial water is?
Subtracting the intracellular water from the total body water gives the extracellular water (15 liters). Since the extracellular water exists primarily of the plasma water and the interstitial water, subtracting the plasma water (4 liters) from the extracellular water (15 liters) gives the interstitial water (11 liters...
4
19 liters
15 liters
21 liters
11 liters
Physiology
null
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single
The most common location of hypeensive intracranial haemorrhage is
Most common locations of hypeensive intraparenchymal hemorrhage are basal ganglia (especially the putamen) thalamus cerebellum pos It usually results from spontaneous rupture of small penetrating aery deep in the brain. Ref : Harrison, 17/e p2531
3
Subarachnoid space
Cerebellum
Basal ganglia
Brain stem
Surgery
Head and neck
453f5d95-7f05-4f29-9385-39e26ea9bf4a
single
For glucose estimation in blood, the mode of transpo from a PHC to lab:
Zinc finger motiff The specificity involved in the control of transcription requires that regulatory proteins bind with high affinity to the Correct region of DNA. Three unique motifs - The helix-turn-helix - Zinc finger - The leucine zipper accounts for many of this specific protein DNA interactions. So zinc finger mo...
2
Sodium fluoride
EDTA
Citrate
0.9% saline
Surgery
null
d462ffb1-0f54-4d4a-b1c3-f6c7ffe0374d
single
A 32-week baby is born to a mother with eclampsia, who was given IV magnesium sulphate. The baby was resuscitated and transferred to the NICU. 12 hours later, the baby showed hypotonia, lethargy, constricted pupils and two episodes of seizures. The staging of HIE is:
Ans. b. 2
2
1
2
3
There is no HIE
Pediatrics
null
f36d3d5d-3476-448b-bb9f-ddd777909bcb
single
Data collection for Active malaria surveillance at PHC level is done by:
Ans. a. MO-PHCSurveillance/ case detection and management. The report of surveillance by ASHA/ MPW/Health facility (M-l) is maintained at every level diagnosing and treating cases like ASHAS/ AWWs/ CHVs at village level, MPWs at sub-center level and MO-PHCs at PHC level.
1
MO-PHC
MPW
DMO
SPO
Social & Preventive Medicine
Health Programmes in India
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single
The minimum distance for two point discrimination on fingeips -
Ans. is'a'i.e., 2mmlRef: Ganong 25th/ep. 170 6 24'h/e p. 1621The magnitude of two point discrimination thresholds varies from place of place on the body and is smallest where touch receptors are most abundant.Stimulation points on the back must be separated by at least 65 mm before they can be distinguished as separate...
1
2 mm
5 mm
7 mm
10 mm
Physiology
null
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single
Which of the secretions does have highest HCO3 level?
The pancreatic juice is alkaline and has a high HCO3- content (approximately 113 mEq/L vs 24 mEq/L in plasma). About 1500 mL of pancreatic juice is secreted per day. Bile and intestinal juices are also neutral or alkaline, and these three secretions neutralize the gastric acid, raising the pH of the duodenal contents t...
4
Saliva
Bile
Succus entericus
Succus entericus
Physiology
null
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single
Fixed drug eruptions can be seen more frequently with –
null
2
Penicillin
Sulfonamide
Cetrizine
Roxithromycin
Dental
null
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single
Most common type of cervical cancer
Ans. A. Squamous cell CA* The two most common histologic subtypes of cervical cancer are squamous cell and adenocarcinoma.* Of these, squamous cell tumors predominate, comprise 85 percent of all cervical cancers, and arise from the ectocervix* Adenocarcinomas comprise 10 to 15 percent of cervical cancers and arise from...
1
Squamous cell CA
Small cell CA
Adeno CA
Adenoma
Gynaecology & Obstetrics
Gynaecological Disorders in Obs.
87dab33b-b526-42cb-9f97-e51e85367ec0
multi
Roth spots are seen in:
Ans: A (Infective endocarditis) Ref; Harrisons Principles of Internal Medicine 18th edition ROTH SPOTS in Infective Endocarditis They are retinal hemorrhages with pale centres. They represent capillary hemorrhages and not bacterial infection. Apart from IE, they can also be seen in vasculitis, anemia, leukemia, diabete...
1
Infective endocarditis
Central retinal vein occlusion
Retintits pigmentosa
Diabetic retinopathy
Unknown
null
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single
A patient presented to casualty with nausea, vomiting. Intravenous glucose was given & the patient recovered. After few months, patient presented with same complaints. Blood glutamine was found to be increased. Also uracil levels were raised. What is the diagnosis?
Increase in Blood glutamine indicates hyperammonemia, which occurs in all enzyme defect of urea cycle Increased uracil indicate Ornithine trans carbamoylase deficiency Orotic acid, OMP, UMP are increased in OTC defect. OTC deficiency (Excess carbamoyl phosphate from mitochondria enters cytoplasm and takes pa in pyrimid...
4
CPS-I deficiency
Argino succinate synthetase deficiency
CPS-II deficiency
Ornithine trans carbamoylase deficiency
Biochemistry
Urea cycle
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single
Normal intrapleural pressure at the sta/beginning of inspiration is----- cm of H2O.
During inspiration, the diaphragm and external intercostal muscles contract, increasing the volume of the thoracic cavity. This causes the intrapleural pressure to become more negative, which increases the transpulmonary pressure, causing the lungs to expand Ref: guyton and hall textbook of medical physiology 12 editio...
2
-7.5
-5
-2
-0.5
Physiology
Respiratory system
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single
Juxtaglomerular apparatus is involved in regulation of-
Ans. is 'a' i.e., Tubulo-glomerular feed back Tubulo-glomerular feedbacko To perform the function of autoregulation, the kidneys have a feedback mechanism that links changes in sodium chloride concentration at the macula densa with the control of renal arteriolar resistance. This feedback helps to ensure a relative con...
1
Tubulo-glomerularfeedback
Glomerulotubular balance
Renal plasma flow
Urinary acidification
Physiology
Glomerular Filtration, Renal Blood Flow, and Their Control
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Behavioral therapy is done in ?
Ans. B. AgoraphobiaMost impoant use of behavioral therapy - Phobia & OCD.Other users are - Other anxiety disorders (including panic), Eating disorders, Autism, ADHD, some personality disorder, sexual dysfunctions, depression.
2
Schizophrenia
Agoraphobia
Delirium
Neurotic depression
Psychiatry
null
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single
The right lobe of liver consists of which of the following segments:
A. i.e. V, VI, VII, and VIII
1
V, VI, VII and VIII
IV, V, VI, VII and VIII
I, V, VI, VII and VIII
I, IV, V, VI, VII and VIII
Anatomy
null
d74b34e6-52ee-4074-bad3-aebf74cbbc7f
single
A 12-year-old child with acute kidney injury after a bout of dysentery. Not seen is:
Ans. (c) Normal serum haptoglobin.
3
M.A.H.A
Schistocytes
Normal serum haptoglobin
Thrombocytopenia
Pathology
Hemolytic anemia
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Stapes is derived from which branchial arch:
Ans (b) IIRef: Inderbir Singh's Embroyology, 7th ed. 1119-120* Ear ossicles are derived from branchial arch I and II* Malleus and incus: BA-I* Stapes: BA- II
2
I
II
III
IV
ENT
Embryology of Ear and Malformations
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single
According to WHO classification of periradicutar diseases, code number category K04.4 is
null
1
Acute apical periodontitis
Chronic apical periodontitis
Periapical abscess with sinus
Periapical abscess with sinus to maxillary antrum
Dental
null
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single
A 34 year old chronic smoker presents to you with progressive claudication of the left arm with ulcers on the ring finger. The patient also gives history suggestive of recurrent superficial phlebitis. There is also history of Raynaud's phenomenon. What is the best treatment for the patient?
The triad of claudication, Raynaud's phenomenon and migratory superficial thrombophlebitis in a young male smoker is typical of thromboangiitis obliterans (Buerger's disease). An aeriography will show segmental occlusion with collaterals. Histopathology will show sharply segmental acute and chronic vasculitis of small ...
4
Steroids
Aspirin
Pentoxifylline
Abstinence from tobacco
Surgery
null
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Scalds are produced by -
Dry heat (e.g. flame) → Simple burns (or burns). Moist heat → Scalde.
2
Dry heat
Moist heat
Severe burns
All
Forensic Medicine
null
b6ddaa47-230e-448c-9a8b-faf336116be1
multi
Infectivity period of chickenpox is: March 2009
Ans. A: 1 day before and 4 days after appearance of rash Chickenpox/ varicella is a highly infectious disease that spreads from person to person by direct contact or by air from an infected person's coughing or sneezing. Touching the fluid blister can also spread the disease. A person with chickenpox is infectious from...
1
1 day before and 4 days after appearance of rash
4 days before and 1 day after appearance of rash
Only when scab falls
Entire incubation period
Social & Preventive Medicine
null
68769fa9-15c9-4316-97d4-ea1532474968
multi
Mechanism of action of azoles is
According to the mechanism of action these can be classified as  Drugs altering membrane permeability  - Azoles  - Triazoles e.g. Fluconazole, itraconazole, voriconazole, terconazole, posaconazole. - Imidazoles e.g. Ketoconazole, miconazole, clotrimazole, econazole, butoconazole, oxiconazole, sertaconazole, sulconazo...
1
By altering membrane permeability
By blocking nucleic acid synthesis
By disrupting microtubules function
By inhibiting cell wall synthesis
Pharmacology
null
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Radioisotopes are used in the following technique except –
ELISA (Enzyme linked Immunoabsorbent Assay) is an enzyme-based immunoassay and does not use radioactive isotopes. A test similar to ELISA which uses radioactive isotope in place of the enzyme is known as Radioimmunoassay (RIA). Nucleic acid sequencing, mass spectroscopy & RIA are tested using radioisotopes.
3
Mass spectroscopy
RIA
ELISA
Sequencing of nucleic acid
Radiology
null
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multi
Erlenmeyer flask deformity is classical X-ray finding in
Refer the byte Sphingolipidoses
2
Pompe's disease
Gauchers disease
Sandhoff's disease
Von Gierke disease
Biochemistry
null
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single
Morphine should not be used in:
Ans. B. Biliary colicOpioids have potent analgesic effect via mu, kappa receptor. They are known to increase the intrabilliary pressure by constricting the smooth muscle. Therefore, they are contraindicated in biliary colic.
2
Ischaemic pain
Biliary colic
Cancer pain
Post-operative pain
Pharmacology
G.I.T
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Permanent mandibular first molar is a common site for all the lesions EXCEPT
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3
Pulp polyp
Condensing osteitis
Lateral periodontal cyst
Benign cementohlastoma
Pathology
null
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Interval between primary and secondary cases ?
Ans. is 'c' i.e., Serial interval Latent period, serial interval and generation time, all are approximate measure of incubation period, i.e., these period can give some idea about incubation period. Latent period The period from disease initiation to disease detection. It is used in non-infectious disease as the equiva...
3
Latent period
Communicable period
Serial interval
Generation time
Social & Preventive Medicine
null
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Which of the following produce gastrin?
D: Endocrine cells produce gastrin. A: Mucous neck cells are found in the necks of the gastric pits. B: Parietal cells produce HCl. C: Chief cells produce pepsinogen E: Foveolar cells or surface mucous cells are mucus-producing cells which cover the inside of the stomach, protecting it from the corrosive nature of gast...
4
Mucous neck cells
Parietal cells
Chief cells
Endocrine cells
Pathology
null
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Which of the following statement is true about vasa pre
Vasa pre: Fetal moality is high (50%) due to fetal exsanguination Vaginal bleeding is often associated with fetal distress Unsuppoed umbilical vessels lie below the presenting pa Ref: Dutta Obs 9e pg 243.
4
Seen in 1:1500 pregnancies
Moality rate is 20% if left undiagnosed
Associated with low-lying placenta
Cesarean section is indicated
Gynaecology & Obstetrics
General obstetrics
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Quinidine belongs to class antiarrhythmic drug is
i.e. (class I): (510-17-KDT 6th) (367-68-MDT-l1)ANTIARRHYTHMIC DRUGSClass Ia Sodium channel blockers* Depress phase O depolarization* Slow conduction, prolong repolarization Drugs* Quinidine, Procainamide, Disopyramide, MoricizineClass Ib * Shorten repolarization Drugs* Lidocaine, MexiletineClass IC * Depress phase O r...
1
Class I
Class II
Class III
Class IV
Pharmacology
C.V.S
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Which of the following jaw cyst is pre-malignant?
Ans. c. Odontogenic keratocyst (Ref: Scott-Brown's Otorhinolaryngology 7/e p1924, 1925)Odontogenic keratocyst is premalignant."Odontogenic keratocysts are characterized by an epithelial lining that is parakeratinized and stratified. It is characterized by basal lender of neatly arranged, palisaded, columnar and cuboida...
3
Nasopalatine cyst
Radicular cyst
Odontogenic keratocyst
Dentigerous cyst
Surgery
Oral Cavity
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According to the European Laryngological Society, Subligamental cordectomy is classified as -
null
2
Type I
Type II
Type III
Type IV
ENT
null
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single
P.Q.L.I is
Physical Quality of Life Index (PQLI) is an attempt to measure the quality of life or well-being of a country. The value is the average of three statistics: basic literacy rate, infant moality , and life expectancy at age one, all equally weighted on a 0 to 100 scale. HDI includes knowledge, income(GNI) and life expect...
1
IMR, Life Expectancy at 1year of age, literacy
MMR, Life expectancy, literacy
MMR, IMR, Life expectancy
IMR, Life expectancy at 1 year of age, SE status
Social & Preventive Medicine
Concept of health and disease
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Which amino acid does not take part in transamination
All amino acids can take part in transamination except: a) Threonine b) Lysine c) Proline
1
Proline
Alanine
Tryptophan
Histidine
Biochemistry
null
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Day care surgery uses
i.e. (Propofol): (81-A-Yadav 4th)Propofol is the IV agent of choice for day care surgeryBecause-(i) Early induction(ii) Early and smooth recovery(iii) Inactive metabolites(iv) Antiemetic antipruritic* Along with opioids (alfntanil or renifentanil) propofol is the agent of choice for total intravenous anaesthesia (TIVA)...
2
Sodium thiopentone
Propofol
Methoxitone
Ether
Surgery
Miscellaneous
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A patient suffers from contraction of maxillary arch, labioversion of maxillary incisors, with deep overbite and overjet. These are features of:
Class II: Dental relationship, in which the mandibular dental arch is posterior to the maxillary dental arch in one or both lateral segments as determined by the relationship of the permanent first molars. Mandibular 1st molar is distal to the maxillary 1st molar. Further subdivided into 2 divisions: Division 1:  Bilat...
3
Class I malocclusion
Class II div 2 malocclusion
Class II div 1 malocclusion
Class III malocclusion
Dental
null
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Commonly undergoing malignant transformation is/are :a) FAPb) Crohn' s diseasec) Ulcerative colitisd) Enteric colitise) Juvenile polyposis
null
3
a
bc
ac
b
Surgery
null
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Gastric carcinoma is associated with all EXCEPT ?
Ans. is 'd' Activation of RAS In the course of multi-step stomach carcinogenesis, various genetic and epigenetic alterations of oncogenes, tumor-suppressor genes, DNA repair genes, cell cycle regulators and cell adhesion molecules are involved. Genetic alteration in gastric cancer include: Intestinal type gastric cance...
4
Inactivation of p53
Over expression of C-erb
Over expression of C-met
Activation of RAS
Pathology
null
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Multiple regression analysis is applied to
null
4
Compare medians of two independent samples
Compare medians of several independent samples
Tests association between two categorical variables
Tests relation between dependent variable and several independent variables
Dental
null
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Most common cause of sub-dural haematoma -
It is due to rupture of bridging veins.
2
Middle meningeal artery tear
Rupture of superior cerebral vein
Internal carotid artery tear
None of the above
Surgery
null
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A child is presenting with vomiting and abdominal pain after 5 hours of eating some food. The most likely causative orgonism -
Ans. is 'a' i.e., Bacillus cereus Wef: Harrison 18th/e p. 1088]o Food poisoning presenting within 6 hours is seen (i) Staph aureus, and (ii) B. cereus.o Cl. botulinum causes constipation (not diarrhea) and the incubation period is about 18-24 hourso V. cholerae has incubation period > 16 hours. OrganismSymptomsFood sou...
1
Bacillus cereus
Cl. perfringens
Cl. botulinum
V. cholerae
Microbiology
Bacillus
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In an old patient, the best indicator of probability of developing cardiovascular disease can be calculated by:-
Ans. is 'a' i.e. LDL/HDL ratio Among the given options the best indicator is LDL/HDL ratio.Recent trials have found out that levels of plasma apolipoprotein A-l and apolipoprotein B are better predictors of CHD than LDL/HDL ratio.
1
LDL/HDL ratio
Triglycerides
Total cholesterol
Serum LDL
Medicine
C.V.S.
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Alpha 2 agonist cause all of the following Except
Ref: KD Tripathi pharmacology 7th edition (page.no: 384) Alpha 2 agonists produce sedation, analgesia, anxiolysis, muscle relaxation, decreases BP they will not increase pain or produce Hyperalgesia eg: clonidine, dexmedetomidine, methyldopa etc
2
Analgesia
Hyperalgesia
Sedation
Anxiolysis
Pharmacology
Autonomic nervous system
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A 30 years old male patient presents with weakness of right upper and both lower limbs since 4 months. He developed digital infarcts involving 2nd and 3rd fingers on right side and 5th finger on left side. On examination, BP was 160/140 mm Hg, all peripheral pulses were palpable and there was asymmetrical neuropathy. I...
Patient in the question is suffering from hypeension, digital infarcts in presence of palpable peripheral pulses and urine examination showing proteinuria and hematuria. All of these are features of polyaeritis nodosa a necrotizing vasculitis of small and medium-sized muscular aeries with characteristic involvement of ...
1
Polyaeritis nodosa
Mixed cryoglobulinemia
Wegener's granulomatosis
Systemic lupus erythematosus
Medicine
null
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What is the most common site of osteosarcoma:
Ans. is 'a' i.e. lower end of femur * Common sites in decreasing order of frequency:Lower end of femur*Upper end of tibia *Upper end of humerusSome other common sites* Osteoclastoma - lower end of femur** Ewing's -tibia** Ivory osteoma -frontal sinus** Osteoid osteoma -tibia** adamantinoma -mandible** Chordoma -sacrum ...
1
Lower end of femur
Upper end of humerus
Lower end of tibia
Upper end of femur
Orthopaedics
Osteogenic Sarcoma
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All are fibrinolytic, EXCEPT :
Ans. is 'd' Epsilon amino caproic acid Antifibrinolytic drugs are :Tranexamic acid*Epsilon aminocaproic acid*Aprotinin*Fibrinolytic drugs are : ,Streptokinase*Urokinase*rt-PA (Alteplase)*
4
Streptokinase
Urokinase
Alteplase
Epsilon amino caproic acid
Pharmacology
Antiplatelets and Fibrinolytics
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The term "dementia" describes all of the following clinical states, EXCEPT:
Dementia is a loss of intellectual functioning. Other operations are affected in dementia, such as language, skilled movements, and perception. However, isolated neurological defects like aphasia are not themselves classified as dementias. Likewise, sensory defects or hemiplegia of body pas would not be included. Nonet...
2
Gradual decline in ceain mental operations such as orientation, cognition, and memory
Presence of a specific language disorder such as aphasia, alexia, or agraphia
Onset of behavioral changes including apathy, eccentricity, and distractibility
Sudden loss of intellectual functioning, such as following an anoxic episode or a cerebrovascular accident
Psychiatry
null
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A drug used in estrogen-dependent breast cancer
Hormonal drug therapy for breast cancer targets estrogen receptor-positive breast cancer. It aims at blocking the action of estrogen on estrogen receptor-positive breast cells. The hormonal therapy of choice for breast cancer in premenopausal women is Tamoxifen. Tamoxifen belongs to a class of drugs known as Selective ...
2
Clomiphene citrate
Tamoxifen
Estrogen
Adriamycin
Anatomy
Endocrinology and breast
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The perinatal HIV transmission can be reduced by the following measures except -
The perinatal HIV transmission can not be reduced by Breastfeeding After bih, babies born to a mother with HIV are given A right away for 4 to 6 weeks. If you are treated for HIV early in your pregnancy, the risk of transmitting HIV to your baby can be 1% or less. Breast milk can have HIV in it. So, after delivery, you...
4
Intrapaum antiretroviral therapy
Delivery by elective cesarean section
Antiretroviral therapy to the neonate
Breastfeeding
Medicine
Infection
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Wof glucocoicoid has significant (max) mineralocoicoid activity
Hydrocoisone (coisol):- Acts rapidly but has sho duration of action. In addition to primary glucocoicoid, it has significant minera- locoicoid activity as well. Uses:- For Replacement therapy, Shock, status asthmaticus, acute adrenal insufficiency. Topically and as suspension for enema in ulcerative colitis. Ref:- kd t...
3
Dexamethasone
Triamcinolone
Hydrocoisone
Betamethasone
Pharmacology
Endocrinology
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single
Inhibition of anaerobic glycolysis by increase supply of O2 is called:
Pasteur effect Warburg effect Crabtree Effect In aerobic conditions, glucose consumption decreases Or In the presence of O2 , anaerobic glycolysis is inhibited Under aerobic conditions, glucose consumption increases Or Even In the presence of O2 , anaerobic glycolysis is promoted (in cancer cells) If glucose increases,...
2
Carbtree effect
Pasteur effect
Lewis effect
null
Biochemistry
Galactose and fructose metabolism
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multi
Carcinoma common in dye industry workers is
Aniline dye is a risk for for TCC of bladder.
1
TCC of bladder
SCC of bladder
Adenocarcinoma of bladder
All of the above
Surgery
null
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multi
Baby born at 30 weeks for 18-year-old prior gravida of weight 2 kg which died after 48 hours. Apgar scores were 5 and 8 at 1 and 5 minutes. On autopsy bilateral enlarged kidney with multiple radially arranged cysts. Which of the following finding is expected to be associated with?
The clinical findings suggest autosomal recessive polycystic kidney disease. The diagnosis of autosomal recessive polycystic kidney disease is strongly suggested by bilateral palpable flank masses in an infant with pulmonary hypoplasia, oligohydramnios and hypertension and the absence of renal cysts in the parents. On ...
2
Imperforate anus
Hepatic cyst and fibrosis
Absence of ureter
Holoprosencephaly
Pediatrics
null
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multi
True about CP angle tumour:
(a) Absent corneal reflex(Ref. Cummings, 6th ed., 2750)Involvement of 3rd and 4th cranial nerve causing pupillary dilatation and medial rectus and superior oblique palsy is not described in Acoustic neuroma.
1
Absent corneal reflex
Superior oblique palsy
Pupillary dilatation
Medial rectus palsy
ENT
Acoustic Neuroma
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multi
A 35-year old male with a history of severe bronchial asthma for several months now complains of weight gain and the development of purple stretch marks. Physical examination shod BP - 149/95 mmHg. supraclavicular fullness. The skin was thinned out with areas of bruising. Neurological examination revealed deceased stre...
Patient developed iatrogenic Cushing syndrome. Bronchial asthma (BA) and Allergic rhinitis (AR) are common clinical problems encountered in day to day practice, where inhalational coicosteroids (ICS) or intranasal steroids (INS) are the mainstay of treatment. Iatrogenic Cushing syndrome (CS) is a well known complicatio...
3
Hyponatremia
Hypomagnesemia
Hypokalemia
Hypercalcemia
Medicine
Respiratory system
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single
Antidote for organophosphorous poisoning is:(1995)
aRef: KDT, 5th ed, p. 91 & 100 & 4th ed, p. 101,89
1
Atropine
Neostigmine
Susccinylcholine
D tubocurarine
Pharmacology
A.N.S.
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single
Which of the these can cause both rhabdomyolysis and myoglobinuria -a) Hyperpyrexiab) Viper snake venomc) Multiple hornet stings d) Anemia
null
1
ac
bc
ad
b
Medicine
null
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multi
A short stature child's growth variation is normal but bone development is not according to chronological age. What is your diagnosis?
Ans. C. Constitutional delayShort stature children with normal growth variation include genetic (familial) short stature and constitutional delay. In genetic short stature bone development matches with the chronological age but not in constitutional delay in which bone development lags behind.
3
Genetic short stature
Dwarfism
Constitutional delay
Growth hormone deficiency
Pediatrics
Growth, Development, and Behavior
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All are symptoms of deep vein thrombosis except:
Ans: a (High grade fever) Ref: Bailey, 24th ed, p. 971 Box-59-8Deep vein thrombosis presents with pain and swelling of the leg. There may be slight fever. High grade fever is not mentioned as a clinical feature of DVT. If the patient has already had pulmonary embolism, he may complain of chest pain, breathlessness and ...
1
High grade fever
Local rise of temperature
Pain
Swelling
Surgery
Venous Disorders
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multi
Chediak higashi syndrome, defect is ?
Ans. is 'a' i.e., Fusion of lysosome Chediak higashi syndrome It is an autosomal recessive disorder. Chediak higashi syndrome is caused due to mutation in the LYST gene. This gene provides instructions for making a protien known as lysosomal trafficking regulator. This protein plays a role in transpo of materials into ...
1
Fusion of lysosome
T-cells
B-cells
Complement
Microbiology
null
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single
Time interval betwen inoculation of infection to maximum infectivity is ?
Ans. is 'c' i.e., Generation time Generation time - Period from receipt of infection to maximal infectivity. Serial interval Gap between onset of primary case and secondary case.
3
Lead time
Median incubation period
Generation time
Serial inverval
Social & Preventive Medicine
null
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single
Surgical treatment of Ulcerative colitisa) Done in late cases onlyb) Done in cases where medical treatment fails c) Pouch surgery doned) Restorative proctocolectomy done in emergency cases
null
1
bc
c
ac
ad
Surgery
null
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single
A 45-year old female had sought medical attention for her recent increase in weight and proximal limb weakness. She was diagnosed with rheumatoid ahritis. 1 week ago has been staed on prednisolone tablets. Physical examamination revealed truncal obesity; BP - 145/90 mm Hg and PR- -90/ mill. High levies of coisol were f...
Most of the signs and symptoms of ACTH-secreting tumors come from having too much coisol (an adrenal steroid hormone). But quite a few diseases can cause the body makes too much coisol, which is called Cushing's syndrome. If you have symptoms suggesting this syndrome, you'll need tests to see if it's caused by a pituit...
2
CT scan of the chest
MRI of the brain
CT scan of the abdomen
Plasma metanephrine level
Medicine
Immune system
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single
Which muscle causes retraction of scapula ?
Ans. is 'c' i.e., Rhomboideus major Movements of scapula Muscles causing movements Elevation Trapezius (upper pa), levator scapulae Depression Pectoralis minor, serratus anterior Protraction Serratus anterior, pectoralis minor Retraction Rhomboideus major Rhomboideus minor, Trapezius Forward rotation of inferior angle(...
3
Serratus anterior
Levator scapulae
Rhomboideus major
Supraspinatus
Anatomy
null
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single
Gas gangrene is/are caused by-
Ans. is 'a' i.e., C.novyi 'b' C.septicum; 'c' i.e., C. histolyticum
4
C. novyi
C. septicum
C. histolyticum
All
Microbiology
null
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multi
Diabetic patient with liver cirrhosis and hyperpigmentation, diagnosis is ?
Ans. is 'b' i.e., Hemochromatosiso Information in the question :?i) Diabetesii) Hyperpigmentationiii) Cirrhosiso Among the given options, only hemochromatosis can cause all three.
2
Wilson's disease
Hemochromatosis
Primary sclerosing cholangitis
Hepatitis B
Pathology
null
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single