question
stringlengths
1
1.57k
exp
stringlengths
1
22.5k
⌀
cop
int64
1
4
opa
stringlengths
1
287
⌀
opb
stringlengths
1
287
⌀
opc
stringlengths
1
286
⌀
opd
stringlengths
1
301
⌀
subject_name
stringclasses
21 values
topic_name
stringlengths
3
135
⌀
id
stringlengths
36
36
choice_type
stringclasses
2 values
A adolescent was bitten by a stray dog. To rule out rabies in the animal, brain tissue sample was taken. Which of the pa of brain tissue should be taken to see the characteristic Negri bodies?
Rapid diagnosis of rabies infection in the animal is usually made by examination of brain tissue by using either PCR assay, fluorescent antibody to rabies virus or histologic staining of Negri bodies in the cytoplasm of hippocampal neurons. Negri bodies are sharply demarcated, more or less spherical, and 2-10 mm in dia...
1
Hippocampus
Hypothalamus
Medulla
Midbrain
Microbiology
null
025ea29e-774e-4651-b97c-4bc0c95e285a
single
All are true about heparin induced thrombocytopenia (HIT), EXCEPT:
Drug induced thrombocytopenia due to heparin has some special features. It will not lead to bleeding. Marked thrombocytopenia < 20,000 is rare. Thrombosis is a major complication. Ref: Harrisons principles of internal medicine, Edition -18, Page - 967
2
Thrombocytopenia is not severe usually
Associated with bleeding especially from GI tract
Marked increase in thrombosis
HIT can occur after exposure to low molecular weight heparin
Medicine
null
7e0d32d1-ff5f-474b-8f58-d9e6703be5e7
multi
The cytoprotective agent used for the prevention of xerostomia in patients undergoing head and neck radiotherapy is
null
2
Valacyclovir
Amifostine
Glycopyrrolate
Naproxen
Pathology
null
0a80bad9-dc8b-4b63-b419-406baa67f016
single
Acute osteomyelitis is most frequently caused by:
Acute osteomyelitis is usually a polymicrobial infection. Different types of organisms may be cultured from these lesions; the most common are Staphylococcus aureus and Staphylococcus albus, and various streptococci. Anaerobes such as Bacteroides, Porphyromonas or Prevotella species also predominate. Ref: Shafer's text...
3
Staphylococcus aureus
Staphylococcus albus
Staph. aureus + Staph. albus
None of the above
Pathology
null
58a62726-6fb9-4e6c-a59a-94706a31f78b
multi
An army recruit, smoker and 6 months into training staed complaining of pain at postero medial aspect of both legs. There was acute point tenderness and the pain was aggravated on physical activity. The most likely diagnosis is:
The army man is most likely suffering from stress fracture. Stress Fracture or fatigue fracture is caused by repeated stress at one point. Bones are constantly trying to repair and remodel themselves in people like athletes and army recruit. Over a period if sufficient stress is applied on a bone which has reached the ...
2
Gout
Stress fracture
Insufficiency stress fracture
Lumbar canal stenosis
Surgery
null
a8239255-e46f-4087-9b33-73819cf92bff
multi
Which of the following drugs is not used for the treatment of cancer
Ref-KDT 6/e p839,840 All antimetabolite can be used as anticancer drugs excepts azathioprine Cyclosporine acts by inhibiting the transcription of IL-2 gene.it has no anti-cancer propey
2
Cyclophosphamide
Cyclosporine
Methotrexate
6-mercaptopurine
Anatomy
Other topics and Adverse effects
cf530308-a4f7-414f-b327-c6e4468b7548
single
The relationship between sulphonamide and PABA is
Sulfonamides have structural similarity with PABA .therefore, they competitively inhibit the enzyme responsible for the incorporation of PABA into dihydropteroic acid, the immediate precursor of folic acidRef: DM Vasudevan, 7th edition, page no: 491, 61
1
Metabolic antagonism
Synergism
Intermediate compound formation
Chelation
Biochemistry
Metabolism of nucleic acids
f35d86f9-3d30-48ed-8e8f-d2a419ebd850
single
Pancreatic islets consist of alpha, beta, and delta cells, which secrete glucagon, insulin, and somatostatin, respectively. These cells are derived from
Pancreatic islets form as isolated clumps of cells that bud from endodermal tubules. As pa of embryonic development, the pancreas forms as two buds from the foregut, an embryonic tube that is a precursor to the gastrointestinal tract. It is therefore of endodermal origin
2
Mesoderm
Endoderm
Ectoderm
Neuroectoderm
Anatomy
Embryology and abdominal wall layer
d93ddf82-f42a-46f2-aa14-a093783dfb56
single
Lallo, aged 54 years, who is a known diabetic patient develops cirrhosis. There is associated skin hyperpigmentation and restrictive cardiomyopathy which of the following is the best initial test to diagnose this case.
Answer is A (Iron binding capacity): The presence of hyperpigmentation and diabetes (bronze diabetes) together with restrictive cardiomyopathy and cirrhosis.suggests a diagnosis of hereditary hematochromatosis. The best initial test to diagnose hereditary hematochromatosis are Transferrin saturation and unsaturated Iro...
1
Iron binding capacity
Serum ferritin
Serum copper
Serum ceruloplasmin
Medicine
null
a2e9a0d5-8983-470a-b01d-0f24fdf723c3
multi
Essential pentosuria is seen in defect of which pathway -
Ans. is 'b' i.e., Uronic acid pathway o Essential pentosuria is an inherited disorder of uronic acid pathway due to deficiency of enzyme L-xylulose dehydrogenase.
2
HMP shunt
Uronic acid pathway
TCA cycle
Gluconeogenesis
Unknown
null
760719cb-5077-435a-b939-979124b237ac
single
Subterminal spores are seen in ?
Ans. is 'a' i.e., Cl perfringens
1
Cl perfringens
Cl tetani
Cl teium
null
Microbiology
null
531aefea-7f74-4e3c-b377-0bef361ed305
multi
All are causes of pulmonary hypeension except,
Hyperventilation [Ref Harrison 17th/e p. 1579; 161h/e p. 14041 There are three main causes of pulmonary hypeension:- i) Cardiac diseases ii) Respiratory disease iii) Pulmonary thromboembolic disease Cardiac diseases -Lead to pulmonary hypeension by increasing pulmonary blood flow (e.g., large left to right shunt) or by...
1
Hyperventilation
Morbid obesity
High altitude
Fenfluramine
Surgery
null
c896aa39-186d-4486-8bb5-405779978906
multi
All of the following are impoant mechanisms of gene transfer in bacteria, except ?
Ans. is 'c' i.e., Veical gene transfer Gene transfer Gene transfer refers to the process of genetic material (e.g. DNA) being sent and received among two organisms-* Donor sends and recipient receives the genetic material. There are two processes of gene transfer :? 1. Horizontal gene transfer (HGT) or lateral gene tra...
3
Lateral gene transfer
Conjugation
Veical gene transfer
Horizontal gene transfer
Microbiology
null
4b90b221-f681-416e-8e0e-698beb968d5a
multi
Atropine causes all except: March 2012
Ans: A i.e. Bronchoconstriction Effects of atropine Atropine causes bronchodilatation and reduced airway resistance, especially in COPD and asthma patients The most prominent effect of atropine is to cause tachycardia Atropine markedly decreases sweat, salivary (dry mouth), tracheobronchial and lacrimal secretion (M3 b...
1
Bronchoconstriction
Tachycardia
Dry mouth
Mydriasis
Pharmacology
null
68924fe4-7d98-4bc6-8bf0-0a07f6f6e79a
multi
Menkes Kinky hair syndrome is characterized by a congenital deficiency of
Menkes disease ("Kinky" or "steely" hair disease) is a disorder of copper metabolism due to mutations in the gene for a copper-binding P-type ATPase, i.e. ATP7A gene.
4
Serum ceruloplasmin
Serum copper
Ferochelatase
Copper binding ATPase
Biochemistry
null
6169974b-3be5-43ea-9f23-f0e102d9cc39
single
Pig in H1N1 influenza acts as?
Pig / swine is reservoir of H1N1 influenza. Reference; Park&;s Textbook of preventive and social medicine, 24th edition.Pg no. 164
3
Carrier
Amplifying host
Reservoir
Vector
Social & Preventive Medicine
Communicable diseases
3a34a796-3c2b-45c7-ba21-c23f640e2611
single
Negri bodies are hallmark of Rabies, these Negri bodies are seen in?
Negri bodies are intracytoplasmic eosinophilic inclusion seen inside the neurons, especially hippocampal pyramidal cells and parking cells.
1
Neurons
Microglia
Astrocytes
Oligodendroglia
Pathology
null
31796089-d45d-4c6c-a1c4-44e1d4933bdc
multi
Trichomoniasis is
Trichomoniasis is non viral sexually transmitted disease. Vertical transmission during birth is possible. It's incidence increases with patient age.
2
Viral sexually transmitted disease.
Marker of high-risk sexual behaviour.
No evidence of vertical transmission.
Incidence decreases with patient age.
Gynaecology & Obstetrics
null
2d22f08a-aea8-4535-93fc-a9b62a639484
multi
Thornwaldt's abscess FALSE is-
null
4
Antibiotics
Marsupialization
Removal of lining
Antihistaminics
ENT
null
0d766562-6547-451c-a2bd-a74ab6636fc1
multi
What is the use of bezlotoxumab?
bezlotocumab is a human Monoclonal antibody used in the treatment to prevemt tht recurrence of clostridium difficale infections. It acts by binding to Fab regions of the antibody and neutralises the toxin B.
3
I
UTI
Cl difficale
Chickenpox
Pharmacology
All India exam
b7468bb7-9904-4a7c-a63b-ea4e3d327490
single
A 65-year-old P3+0 female complains of procidentia. She has past history of MI and is diabetic and hypeensive. Ideal management of prolapse in the patient is
Le fo&;s repairReserved for elderly patients with an advanced prolapse or for those women who are medically unfit The procedure can be performed under sedation and local anesthesia or epidural anesthesiaProcedureThe flaps of the vagina from the anterior and posterior vaginal walls are excised and raw areas are opposed ...
4
Cervicopexy
Vaginal hysterectomy
Wait and watch
Le fos repair
Gynaecology & Obstetrics
Urogynecology
58aa60b7-de56-49f8-bdc3-f902bdac64e0
single
A population of 1000 people in whom the prevalence of disease XYZ is 50%. ABC screening test was used to screen disease which has specificity and sensitivity of 50 %. What is positive predictive value of screening test ABC.
Total Population = 1000 Prevalence = 50% People have Disease = 500 Not have Disease = 500 Method 1 Test Disease [?] Th [?] A TP ? B FP ? Th C FN ? D TN ? 500 (given) 500 (given) 1000 (given) Test Disease [?] Th [?] A 250 B 250 Th C 250 D 250 Method 2 ( Baye's Theorum)
1
50%
25%
75%
10%
Social & Preventive Medicine
Screening
c74c496a-749d-49e1-a14b-02219d9f2111
single
Increased Gamma efferent discharge is seen in all except
(D) Rapid shallow breaking # Increased Gamma efferent discharge> Anxiety (hyperactive tendon reflexes)> Stimulation of skin, especially by noxious agent> Jendrassik's maneuver (trying to pull the hands apart when the flexed fingers are hooked together facilitates the knee-jerk reflex).
4
Anxiety
Jendrassik's manoeuvre
Stimulation of skin
Rapid shallow breathing
Physiology
Nervous System
f48fab39-b459-4691-aa64-2fa0f537564f
multi
Plant penicillin is -
Organochlorine insecticides are chlorinated hydrocarbons and are divided into four types as: * DDT (dichlorodiphenyl-trichloroethane) and analogues * Benzene hexachloride group -- e.g. BHC, lindane * Cyclodines and related compounds -- e.g. endrin, aldrin,dieldrin, endosulfan, sobenzan * Toxaphene and related compounds...
3
CarbamateT
OPC
Endrin
DD
Forensic Medicine
Poisoning
fdff24e5-fe4a-432b-926a-43f607c62018
single
Which of the following is not a congenital anomaly?
Mastitis is an inflammation of breast tissue that sometimes involves an infection. The inflammation results in breast pain, swelling, warmth and redness. You might also have fever and chills. Mastitis most commonly affects women who are breast-feeding (lactation mastitis) . Ref - medscape.com
4
Amastia
Polymastia
Polythelia
Mastitis
Anatomy
General anatomy
cb167b75-f340-481f-9b8d-3916693ff8c5
single
FROMENT'S SIGN is due to which nerve injury?
FROMENT'S SIGN/BOOK TEST: - Tests Adductor pollicis muscle - It is innervated by ULNAR NERVE - In ulnar nerve injury, when the patient is asked to grasp a book firmly b/w thumb & other fingers of both the hands, Terminal phalanx of thumb on paralysed side becomes flexed at interphalangeal joint
3
Intercostobrachial nerve
Radial nerve
Ulnar nerve
Median nerve
Anatomy
Nerve supply, Nerve Lesions
569884e1-8525-44a3-ba9c-0fdf93b31614
single
Cholesterol is not a precursor for synthesis of:
Cholesterol is a precursor for synthesis of : Vitamin D, Steroid hormones Bile acids Lipocoin/ Annexin, inhibitor of phospholipase A2 enzyme. Increased expression of the gene coding for annexin-1 is one of the mechanisms by which glucocoicoids (such as coisol) inhibit inflammation.
3
Vitamin D
Bile acids
Lipocoin
Progesterone
Biochemistry
Cholesterol synthesis and bile acids
4730fc88-336d-4c5c-8280-8767ddf4b6f2
single
True regarding the development of ear: (PGI Dec 2007)
Ans: A (Eustachian tube..); B (Eustachian tube.,); C (Pinna develops..) & D (Growth of the inner,.) Eustachian Tubeit connects nasopharynx with the tympanic cavity. In adults it is about 36 cm long & runs downwards, forwards media] ly from its tympanic end, forming an angle of 45 with the horizontal.The tympanic end of...
1
Eustachian tube opens at the level of inferior turbinate
Eustachian tube develops from the cleft of first arch
Pinna develops from the cleft of 1st arch
Growth of the inner-ear completed by 4tb month
Unknown
null
510ca6ca-119a-41d5-9cb1-1548b28c6b9a
multi
All of the following drugs are associated with pure red cell aplasia except
null
4
Phenytoin
Azathioprine
Chloramphenicol
Ethambutol
Medicine
null
ef5f028e-ed75-4eff-ab33-7cdcdb5550b4
multi
Which of the following statements is true of cholera enterotoxin?
.
1
Appears to produce its effect by stimulating adenyl cyclase activity in mucosal cells
Causes destruction of the intestinal mucosa allowing for invasive infection
Causes a net efflux of ions and water from tissue into the lumen of the large intestine
Is a protein with a molecular weight of about 284,000
Pathology
All India exam
89bd391a-fbc1-41e5-b7ca-e0db002ff919
multi
The antistreptolysin O (ASO) titer is used in the diagnosis of:
The antistreptolysin O (ASO) titer is the most commonly used streptococcal antibody test to establish a recent streptococcal infection and acute rheumatic fever (ARF). An ASO titer of 240 Todd units or higher in adults or 320 Todd units or higher in children is considered modestly elevated. ASO titers above 500 Todd un...
2
Acute rheumatoid ahritis
Acute rheumatic fever
Ankylosing spondylitis
Osteoahritis
Pathology
null
840e8102-4c5d-4986-b260-4465c9d529b8
single
A 57-year-old male patient with a history of alcoholism has decided to stop drinking. Of the following, the agent most commonly used to treat anxiety and agitation associated with the initial stages of alcohol withdrawal is
Chlordiazepoxide Because it is long-acting and has relatively low abuse potential, chlordiazepoxide is the antianxiety agent most commonly used to treat the anxiety and agitation associated with the initial stages of alcohol withdrawal.
4
zaleplon
flurazepam
clonazepam
chlordiazepoxide
Psychiatry
Substance Related and Addictive Disorders
8c320b20-e222-4354-87e9-20f390d41700
single
M.0 cause of liver abscess:
Ans. (c) E. coli Remember: E.coli is MC cause of: - intraabdominal abscess - Neonatal meningitis - UTI. Note: Most common manifestation of E. coli : Diarrhea > UTI > Abdominal and pelvic infection
3
Streptococcus
Staph'aureus
E. coli
Staph pyogenes
Microbiology
null
3c7aa4ca-6d68-4f79-ab46-5aaaa06d1192
single
Lovastatin causes
Ans. is 'a' and 'c' i.e., Increased LDL receptor and Decreased LDL cholesterol Statins -Mechanism of action -Decrease the synthesis of cholesterol by inhibition of rate limiting enzyme HMG CoA. reductase.Effect on lipids Decrease in lipids Decrease Triglycerides Increase HDLStatins decrease synthesis of cholesterol by ...
1
Increased LDL receptor
Decreased HDL cholesterol
Decreased LDL cholesterol
Increased SGOT/SGPT ratio
Pharmacology
Hypolipidemic
aaedaaf0-f40f-4e3c-a6f5-040b55fa5c78
single
Metrinidazole is least likely to be effective in the treatment of
Ref-KDT 6/e p686 Metranidazole is not effective against pneumocyst infection. The DOC for this condition is cotrimoxazole
1
Hepatic amoebiasis
Infection caused by bacteroides fragilis
Pseudomembranous colitis
Pneumocystosis
Anatomy
Other topics and Adverse effects
bfd34a13-911f-43c3-a863-a40c44ad4857
single
All are true regarding the enamel spindles except:
Enamel spindles are formed by extensions of odontoblast processes into enamel before calcification. They are odontoblastic processes that cross the dentinoenamel junction and get entrapped in the enamel.
1
Produced by ameloblasts
Found in the region of cusps
Surrounded by interprismatic enamel
Terminate as rounded process
Dental
null
4debacc9-abe0-44fb-87e5-a8c407fd4d8e
multi
Uretheritis is seen in:
Answer is A (Reiter's Syndrome): Syndrome is characterized by the triad of urethritis, conjunctivitis and ahritis.
1
Reiter's syndrome
Gout
Rheumatoid ahritis
PAN
Medicine
null
ae8c8dfe-e1eb-4333-b144-773fcfb7d94e
single
The syndromic management of urethral discharge includes
Ans. c. Neisseria gonorrhoeae and Chlamydia trachomatisSyndromic ManagementUrethral discharge: Neisseria gonorrhoeae and Chlamydia trachomatisGenital ulcer disease: Syphilis and Chancroid
3
Neisseria gonorrhoeae and herpes genitalis
Chlamydia trachomatis and herpes genitalis
Neisseria gonorrhoeae and Chlamydia trachomatis
Syphilis and chancroid
Skin
S.T.D.
a86f01ca-8812-42ff-a67d-6227a2f107da
single
Splenectomy can lead to: September 2005
Ans. B: Thrombocytosis Thrombocytosis sometimes occurs after spleen-removal surgery. Spleen holds approximately one-third of the blood platelets that are in the human body. So, it stands to reason that the removal of the spleen would prompt an increase in blood-platelet circulation throughout the body. The thrombocytos...
2
Leucopenia
Thrombocytosis
Thrombocytopenia
Thrombocytopenia and leucopenia
Surgery
null
6b07e7cb-b1ab-4eb4-b651-4c3255fe2218
single
Which antimalarial drug can be safely administered baby with gluc ose-6-phosphate dehydrogenase' deficiency:
Chloroquine
1
Chloroquine
Quinine
Mefloquinine
Primaquine
Pharmacology
null
9b166cec-7c0d-4605-99dc-ec7defcfb021
single
International disease surveillance is for
Diseases under WHO surveillance  Polio Rabies Relapsing fever Influenza Salmonella Malaria Louse born typhus
3
Hepatitis
TB
Polio
Leprosy
Social & Preventive Medicine
null
c7779db7-05bb-4067-b727-a8910157a0bc
single
Sperm motility is increased in
Sperm motility describes the ability of sperm to move properly through the female reproductive tract (internal feilization)Ref: Ganong&;s review of medical physiology;24th edition; page no:-421
3
Increased temperature
Acidic environment
Vaginal secretions
Seminiferous tubules
Physiology
Endocrinology
272a5790-14d5-40a1-b60d-0d7326e0e76a
single
A 24-year-old man on chronic corticosteroid therapy for severe asthma presents with a 6-month history of increasing hip pain. This patient most likely exhibits symptoms of which of the following metabolic bone diseases?
Risk factors for osteoporosis include smoking, vitamin D deficiency, low body mass index, hypogonadism, a sedentary lifestyle, and glucocorticoid therapy (seen in this patient). Bone loss and fractures are the hallmarks of osteoporosis, regardless of the underlying cause. Choices A and C are congenital disorders that a...
4
Gaucher disease
Osteomalacia
Osteopetrosis
Osteoporosis
Pathology
Osteology
080352ad-7e86-4226-b64e-f49556d40ecc
single
A 54-year old woman complains of hot flashes and night sweats. Her last menstrual period was 2 years ago. She also has migraine headaches and a family history of breast cancer her maternal aunt. What is the appropriate treatment for her?
This 54-year old woman has vasomotor instability and needs hormonal replacement. Because she has two contraindications to estrogen therapy (migraine headaches and a family history of breast cancer), medroxyprogesterone acetate is the best treatment of choice. Even though it is less effective than estrogen, it still can...
3
Hysterectomy
Endometrial biopsy
Medroxyprogesterone acetate
Estrogen cream
Gynaecology & Obstetrics
null
cfef42d6-816c-4a75-a78b-eda83b00c201
single
Which of the following areas of the oral cavity are affected by inflammatory papillary hyperplasia?
null
3
Lips
Tongue
Palate
Gingival
Dental
null
64376635-171e-438a-b5bd-b62a74125964
single
The quadrangular space is bounded by the following structures, except the-
Ans. C. DeltoidTHE QUADRANGULAR AND TRIANGULAR SPACESa. Anteriorly, the quadrangular space is bounded by subscapularis, the capsule of the shoulder joint and teres minor above, teres major below, the long head of triceps medially, and the surgical neck of the humerus laterally.b. Posteriorly, the quadrangular space is ...
3
Surgical neck of the humerus
Long head of triceps
Deltoid
Teres major
Anatomy
Upper Extremity
78480f96-9e01-4bd3-adcf-80566c5738af
multi
True about Salmonella typhi infection in intestine are:
Ans. (a) Affects Peyer's patches Enteric manifestations of S.typhi: S. typhi invades peyer's patches and form oval ulcer with their long axis along the length of bowel (Tuberculosis result in transverse ulcer). Peyer's patches lie along antimesentric border, so ulcer are common in antimesentric border. Stricture is rar...
1
Affects peyer's patches
Common in mesenteric border
Erythrophagocytosis is characteristic
Strictures are common
Microbiology
null
0598f0a7-338a-4e61-9a4f-06c76618de74
multi
Ghost (shadow) cells are seen in
null
4
Arnetoblastic fibroodontoma
calcifying odontogenic cyst
compound odontoma
all of the above
Pathology
null
1db7b701-6c33-436b-8f04-ee586d74a404
multi
Following cailage are derivative fo Second arch except
Human embryology Tenth edition Inderbir Singh's Pg 132 The cailage of the second arch forms the following: Stapes Styloid process Stylohyoid ligament Smaller cornu of hyoid bone Superior pa of body of hyoid bone The following structures are derived from cailage of third arch Greater cornu of hyoid bone Lower pa of body...
2
Smaller cornu of hyoid
Greater cornu of hyoid
Styloid process
Stylohyoid ligament
Anatomy
General anatomy
b10301f0-c166-4b48-8e69-f7211ea75869
multi
Antidepressant drug that can he used in nocturnal enuresis is?
In children above 5 years, imipramine 25 mg at bedtime is effective, but bed wetting may again sta when the drug is stopped. Eldery subjects with bed wetting have also benefited. REF: KD Tripati 8th ed.
1
Imipramine
Fluvoxamine
Phenelzine
Bupropion
Pharmacology
Central Nervous system
ff4bc088-992a-4144-822d-66c62e41baba
single
Which of the following treatments for menorrhagia is not supported by evidence?
Ans. is 'b' i.e. Ethamsylate Ethamsylate has a dubious role in treatment of menorrhagia. Tranexamic acid, progesterone and combined OCP, all have proven role in treatment of menorrhagia."Ethamsylate is thought to act by reducing capillary fragility, though the precise mechanisms are uncertain. Studies with objective MB...
2
Tranexamic acid
Ethamsylate
Combined OCP
Progesterone
Gynaecology & Obstetrics
Heavy menstrual bleeding
901ca567-6109-4f86-a5da-0db18a0c6741
single
During the process of chlorination of water, the disinfecting action of chlorine is due to the formation of-
Ans. is 'd' i.e., Hypochlorous acid and hypochlorite ions
4
Hydrochloric acid only
Hypochlorous acid only
Hydrochloric acid and hypochiorite ions
Hypochiorous acid and hypochiorite ions
Social & Preventive Medicine
null
7a9c4356-41c6-4280-9067-5266020330f8
single
Which of the following does not occur in mitochondria?
null
2
TCA cycle
HMP Shunt
Urea cycle
Beta oxidation of fatty acids
Biochemistry
null
b5219c88-01c6-4d07-acc6-7093c55634f0
single
The net protein utilization of rice is -
1gm of protein is assumed to be equivalent to 6.25g of N. Rice contain 7g of protein. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 584
3
20%
40%
63%
81%
Social & Preventive Medicine
Nutrition and health
7c6366c2-5120-4b5d-851f-06b8c5f6886e
single
All are serotonin recuptake inhibitor except:
Selective serotonin reuptake inhibitors (SSRis) Fluoxetine, Fluvoxamine, Paroxetine, Seraline, Citalopram, Escitalopram Ref: K D Tripathi 8th edition
4
Fluoxetine
Fluvoxamine
Paroxetine
Amoxapine
Pharmacology
Central Nervous system
52b6adcc-5a72-46f9-b036-a0f7aca2c586
multi
Meningitis with rash is seen in -
null
1
Neisseria meningitidis
H. influenzae
Strep. agalactiae
Pneumococcus
Microbiology
null
89245ed2-d952-4573-9b09-7fbc2a61fcde
single
Cutaneous innervations of dorsum of foot are marked in the given diagram. The area D supplied by
Common peroneal nerve wind around the neck of fibula and divide into superficial and deep peroneal nerve Superficial peroneal nerve (musculo cutaneous nerve of lower limb) - supplies peroneus longus and brevis Deep peroneal nerve - supplies extensor compament of leg CHOICE EXPLANATION & ELIMINATION REASON 1 B - area su...
2
Deep peroneal nerve
Superficial peroneal nerve
Tibial nerve
Sciatic nerve
Anatomy
Nerve supply of Lower Limb
43a40644-73eb-4796-a552-ec87c21968ff
single
Amyloidosis is commonly associated with:
null
4
Chronic osteomyelitis
Periostitis
Acute osteomyelitis
Multiple myeloma
Pathology
null
5b6722ce-20f4-4735-a1a3-fdbff9e9a1ed
single
Prostaglandin analogs have therapeutic utility in the following EXCEPT :
Prostaglandin analogs are useful for Pulmonary hypertension Impotence Peptic ulcer Bronchial asthma Inflammatory bowel disease Remember, For PDA, indomethacin (drug decreasing PGs) is used.
1
Palliative treatment of patent ductus arteriosus
Pulmonary hypertension
Impotence
Inflammatory bowel disease
Pharmacology
null
1f0908f8-c072-4be5-8423-d861030631a0
multi
Disseminated seminoma is treated by
null
1
CT or RT and orchidectomy
Only RT
Only CT
Retroperitoneal lymphnode dissection
Surgery
null
139bdc6f-283c-4d4d-9369-92b12c869f41
single
A patient presents with macroglossia and loss of tongue papilla. His Hb is 11.5 and MCV is 100. What should be the next step in investigating this patient?
null
1
B12 estimation
Brush biopsy of the lesion
Fluconazole treatment
Incision biopsy
Medicine
null
84baa9d6-7ced-4bcc-b803-b611f5de3e34
multi
A 25-year-old woman complains of headache for 4 months duration. She is obese and has bilateral papilledema, and her vision is deteriorating. Her opening CSF pressure is elevated; other CSF findings are normal. CT and MRI scans are normal. These signs are due to the result of impairment of CSF egress. At which of the f...
Condition - Pseudotumor cerebri (benign intracranial hypeension), seen primarily in young obese women between the age of 20 and 50. -likely due to high pressure within the skull caused by the buildup or poor absorption of cerebrospinal fluid (CSF) by Arachnoid villi activity. -Symptoms of pseudotumor cerebri include he...
1
Arachnoid villi
Cerebral aqueduct
Foramen of Luschka (lateral)
Foramen of Magendie (median)
Anatomy
Development of nervous system and cerebrum
aab1c795-d0b4-4276-8a05-8e91a99d8cf0
single
During endoscopic biopsy of a distal esophageal cancer, perforation of the esophagus is suspected when the patient complains of significant new substernal pain. An immediate chest film reveals air in the mediastinum. You would recommend
Esophagogastrectomy celiotomy ......... Perforation of the esophagus in the chest is a surgical catastrophe that requires aggressive intervention in viually all circumstances. While that intervention can usually consist of effos to patch the perforation and drain the mediastinum concomitant obstructive esophageal disea...
4
Placement of a nasogastric tube to the levels of perforations, antibiotics, and close observation
Spit fistula (cervical pharyngostomy) and gastrostomy
Left thoracotomy, pleural patch oversewing of the perforation, and drainage of the mediastinum.
Esophagogastrectomy celiotomy and right thoracotomy
Surgery
null
790b248f-dd11-431c-9621-ae33a3e499d4
single
True statement regarding 'Fistula in ano' is -
null
4
Posterior fistulae have straight tracks
High fistulae can be operated with no fear of incontinence
High and low divisions are made in relation to the pelvic floor
Intersphincteric is the most common type
Surgery
null
f0627f9a-0356-4ea8-b748-03680866f8bb
multi
Pastia's lines in scarlet fever are
null
3
White lines on the dorsum of the tongue
Seen bilaterally on buccal mucosa
Present in skin folds secondary to capillary fragility
Seen when white and red strawberry tongue occur concomitantly
Surgery
null
bd045c2d-c9e3-481d-bd02-39296c4973da
multi
Composites usually do not need pulp thermal protection below it because they have:
Composites usually donot need liners and bases for thermal protection as they are poor conductors of heat and have low thermal conductivity. They may need liners for pulp capping and also to reduce effects of polymerization shrinkage but not for thermal protection. Reference- Sturdevant 6th ed
3
High Linear coefficient of thermal expansion
High density
Low thermal conductivity
All of the above
Dental
null
f1422814-8f47-4399-b6ee-22f1dbefc50e
multi
Indication for surgery in benign prostatic hyperophy are all except: 1. Urinary retention 2. Frequency 3. Enlarged prostate
| freuency & enlarged prostate are not an indication for surgery in BPH. Absolute indications for surgery in BPH Refractory urinary retention (falling at least one attempt catheter removal) Recurrent UTI. Recurrent gross hematuria Bladder stones (BS) Renal insufficiency Minimal improvement or medical treatment.
4
Only 1
1 & 2
2 & 3
1, 2 & 3
Surgery
Prostate and seminal vesicles
1b36c303-3642-4846-b367-a63a56061cd2
multi
Which of the following is not asked in personal history in a psychiatric disorder?
Food preferences is not a standard component of psychiatric history. The impoant components of personal history in psychiatry include the following: 1. Perinatal history 2. Childhood history 3. Educational history (Academic history) 4. Occupational history 5. Sexual and marital history 6. Menstural history
3
Occupational history
Academic history
Food preferences
Marital history
Psychiatry
Basics of Psychiatry
e2d7f4ae-8862-455a-90b0-2089f366fb52
single
Which of the following chemotherapy agent can cause SIADH?
Neoplasms: Carcinoma - lung, duodenum, pancreas, ovary, Mesothelioma, Branchial adenoma, Carcinoid, Ewing sarcoma Head trauma Infections- Pneumonia, Abscess (lung or brain), Cavitation (aspergillosis), TB (lung or brain), Meningitis (Bacterial or viral) Encephalitis, AIDS Vascular: Cerebrovascular occlusions, hemorrhag...
1
Vincristine
Doxorubicin
Dacarbazine
Cyclophosphamide
Pharmacology
Chemotherapy
fce35113-0788-44b2-9d15-f868f68ccb5f
single
KISA% is associated with-
Ans. is 'a' i.e., Keratoconus * The KISA index is used in cases of keratoconus and is derived using 4 indices:i) Central keratometry Kii) Inferior- Superior keratometry (I-S)iii) Astigmatism Index (AST)* It is calculated using videokeratograph device and it quantifies th degree of corneal astigmatism and the SRAX index...
1
Keratoconus
Keratoglobus
Hypermetropia with astigmatism
Terrien's marginal degeneration
Ophthalmology
Cornea
043e7630-9174-4b95-805a-6ef9849924bf
single
Recurrent chalazion in old age may indicate: March 2004
Ans. C i.e. Adenocarcinoma of the meibomian giana
3
Squamous cell carcinoma
Basal cell carcinoma
Adeno carcinoma of the meibomian gland
Sebaceous gland carcinoma
Ophthalmology
null
13a8f81e-fa2b-4225-bc58-75f065837d81
single
Hyperangina is caused by ?(
Hepangina is caused by Coxsackie viruses Ref Harrison20th edition pg 980
4
Echovirus
Coxsakie virus
Enterovirus
All of the above
Medicine
Infection
fa2aff66-70cc-4949-b3c5-5476f72e27f5
multi
Omalizumab is used in treatment of:
Omalizumab is a blocking antibody that neutralizes circulating IgE without binding to cell-bound IgE; it thus inhibits IgE-mediated reactions. This treatment has been shown to reduce the number of exacerbations in patients with severe asthma and may improve asthma control. However, the treatment is very expensive and o...
2
Breast carcinoma
Asthma
Rheumatoid ahritis
None of the above
Medicine
null
67687939-f2be-4168-9d3d-d4282e3df301
multi
Pautrier's micro-abscess is a histological feature of-
Ans. is 'c' i.e., Mycosis fungoides Pautrier's microabscesses is a histopathological characteristics of mycosis fungoides.Pautrier's micro abscesses * It is an intraepidermal collection of atypical lymphocytes and band of lymphoid cells in the upper dermis. More on mycosis fungoidesIt is a malignant tumour of dermis.It...
3
Sarcoidosis
Tuberculosis
Mycosis fungoides
Pityriasis Lichenoides Chronica
Skin
Skin Cancer
6bc37353-1bdb-419a-acba-bc062beaaf51
single
Possibility of veical transfer of HIV infection if prophylaxis is given: March 2007
Ans. A: 1% Possibility of veical transfer of HIV infection in pregnant woman who are receiving combination antiretroviral therapy is approaching 1%.
1
1%
2%
3%
4%
Medicine
null
76c65ee0-b325-4970-a680-2306166f1a3b
single
a new agent was developed to increase the recognition of foreign antigens by antigen presenting cells .true regarding the physiological aspects of APCs
EXOGENOUS ANTIGENS ARE FIRST PHAGOCYTOSED BY APCs THEN THEY ARE PROCESSED BY APC s and presented on the surface of apc along with mhc 2 to be recognised by cd4+ t cells antigen Presenting Cells Antigen-presenting cells (APCs) are specialized cells, which include macrophages, B lymphocytes, and dendritic cells, are dist...
4
antigen is presented MHC-1 complexes
APCs are required before a response to viruses are generated
direct antibody stimulation still requires APCs
antigen processed by APC are recognised by CD 4+ tcells
Microbiology
All India exam
116faa47-969d-4426-b740-30afa252a36a
multi
In addition to ETEC another strain of E.coli that causes Travellers diarrhea is
.Enteropathogenic Escherichia coli (EPEC) is a non-Shiga toxin-producing strain of E. coli that causes diarrhea an "attaching and effacing" mechanism on the surface of enterocytes . In adults, EPEC diarrhea presents as watery diarrhea (sometimes associated with vomiting) in association with a low-grade fever
3
EIEC
EHEC
EAEC
EPEC
Pathology
All India exam
a098ecb0-6192-48a6-9151-117529c55c9a
single
Combination of Sparfloxacin and Terfenadine can cause:
Drugs that prolong Q-T interval : CLASSIFICATION DRUGS 1. Antiarrhythmics Quinidine, Procainamide, Disopyramide, Propafenone, Amiodarone 2. Antimalarials Quinine, Mefloquine, Aemisinin, Halofantrine 3. Antibacterials Sparfloxacin, Moxifloxacin 4. Antihistaminics Terfenadine, Astemizole, Ebastine 5. Antidepressants Amit...
4
Myopathy
Nephropathy
Electrolyte imbalance
Ventricular arrhythmia
Pharmacology
Antimetabolites and Quinolones
43612bcd-8624-41f1-9101-b7d322b8fb20
single
All of the following are absoulate indications for intubation except -
Ans. is 'd' i.e., Maxillofacial fractures o Basic indications for emergency endotracheal intubation1. Airway blockage# Life-threatening airway obstruction may occur when a foreign bodybecomes lodged in the airway; this is especially common in infants and toddlers.# Severe blunt or penetrating injury to the face or neck...
4
Depressed level of consciousness
Bleeding into the airway
Falling O2 Saturation
Maxillofacial fractures
Surgery
Maxillo Facial Injuries
53554b50-af30-4572-b551-6b0624450381
multi
Swimming pool granuloma is caused by: March 2010
Ans. C: Mycobacterium marinum Aquarium granuloma/ Fishtank granuloma/swimming pool granuloma results when water containing an infectious organism, Mycobacterium marinum, enters a break in the skin. A localized infection called a granuloma results after about 3 weeks. The person usually has a history of exposure to swim...
3
Mycobacterium chelone
Mycobacterium kansasii
Mycobacterium marinum
Mycobacterium ulcerans
Microbiology
null
54f2cc7e-a366-4df9-9d66-bcda14adde8a
single
True about Epidural anesthesia:
B i.e. C/I in coagulopathies Epidural anaesthesia is given in epidural spaceQ (extending from foramen magnum to sacral hiatus) not in subarachnoid spaceQ (which is used for intrathecal - spinal anesthesia). In comparison to spinal anesthesia, the volume of drug given is larger, onset on effect is delayed (5-20 min) and...
2
Effects sta immediately
C/I in coagulopathies
Given in subarachnoid space
All
Anaesthesia
null
7478f151-8219-4e89-93ea-1a3a5169460c
multi
Post operative ileus is maximum in:
null
1
Colon
Ileum
Duodenum
Stomach
Surgery
null
aa258d14-2361-43e9-8546-8bef162e6980
single
The distance between tympanic membrane and medial wall of middle ear at the level of center is -
null
4
3mm
4 mm
6mm
2 mm
ENT
null
a43c9d5c-4248-4149-9d21-3ee82ef14edd
multi
Which drug is not used for acute bronchial asthma ?
Ans. is 'a' i.e., Salmeterol Bambuterol is a prodrug of terbutaline. It is slowly hydrolysed by pseudocholineterase. Sho acting 132-agonists produce bronchodilatation within 5 min and action lasts for 2-6 hrs --> are used to abo and terminate acute asthma, but are not suitable for prophylaxis. Salmeterol is delayed act...
1
Salmeterol
Formeterol
Salbutamol
Coicosteroids
Pharmacology
null
eae4ca0e-4348-4044-92e1-f8809bb09041
single
Regulation of coronary circulation is?
The caliber of the coronary vessels, and consequently the rate of coronary blood flow, is influenced not only by pressure changes in the aoa but also by chemical and neural factors. The coronary circulation shows considerable autoregulation.Ref: Ganong's Review of Medical Physiology Twenty-Third Edition Page No: 579
2
Autonomic
Autoregulatory
Hormonal
Sympathetic
Physiology
Cardiovascular system
94a28666-14fd-4874-94c4-6cc3babccd7d
single
In testicular tumours
(Maldescent of testis leads to malignancy) (1411-LB) (1385-B & L 25th)Tumours of the Testes* About 99% of testicular neoplasm are malignant and although they make up only about 1 -2% of malignant tumours (MC tumours in young males)* **Maldescent undoubtedly predisposes to malignancy.* Tumours of testis = Seminoma (40%)...
2
Only 10% are malignant
Maldescent of testes leads to malignancy
Extremely painful
Excoriation of the superficial skin
Surgery
Testis & Scrotum
050bf53f-7568-4a4f-a381-e8c7c1d36222
single
Which of the following changes in pregnancy needs fuher evaluation ?
Atrial and ventricular premature contractions ,15deg Left Axis Detion and mild ST changes in inferior leads are considered normal during pregnancy. Criteria for diagnosing Hea Disease in Pregnancy (Finding Suggestive of Hea Disease in Pregnancy). Symptoms: Progressive dyspnea or ohopnea. Nocturnal cough Hemoptysis Sync...
3
Ventricular premature contractions
15deg Left Axis Detion
Cardiomegaly
Mild ST changes in inferior leads
Gynaecology & Obstetrics
Physiological Changes of Pregnancy
72da6ec6-5c85-45de-a0e4-f4d27d4f9faa
single
The following is not true of candida albicans -
Candida (GPOBYC) is yeast like fungi. Chlamydospores are typically produced by C. albicans on cornmeal agar at 25degC, but not by other Candida species. C. albicans can cause meningitis in immunocompromised patients. Blastomere - seen in Hookworm egg
3
Yeast like fungus
Forms chlamydospores
Blastomeres seen in isolates
Causes meningitis in immunocompromised
Microbiology
Mycology
bd623a46-10bd-496c-947f-5dc05034c284
multi
The most serious alkali burns of the eye are produced by
CHEMICAL INJURIES Alkali burns: Alkali burns are among the most severe chemical injuries known to the ophthalmologists. Common alkalies responsible for burns are: lime, caustic potash or caustic soda and liquid ammonia (most harmful). Clinical picture: It can be divided into three stages: 1. Stage of acute ischaemic ne...
2
Caustic soda
Liquid ammonia
Lime
None of the above
Ophthalmology
Ocular trauma
6062f823-2f26-453f-90ab-d20b6c53de73
multi
What is the Iron and Folic acid requirement of 6 months to 10 year old children?
As per Rajiv Gandhi scheme for empowerment of adolescent girls (SABLA) Children between 6 months to 60 months should be given 20 mg elemental iron and 100 microgram folic acid per day per child. The tablets for mothers contain 60 mg elemental iron and 500 microgram folic acid and those for children contain 20 mg iron a...
1
20 mg elemental iron and 100 microgram folic acid
100 mg elemental iron and 500 microgram folic acid
60 mg elemental iron and 500 microgram folic acid
100 mg elemental iron and 1000 microgram folic acid
Pediatrics
null
5b1e5c41-491a-4e67-bbda-c6bb97aa4930
single
Best prognosis in CA GB is seen in
Histological types in gallbladder Carcinoma Diffuse infiltrative :MC type Nodular or mass forming Papillary : Exhibits polypoid or cauliflower appearance and have best prognosis Adenocarcinoma : MC histological subtype of CA GB Ref: Sabiston 20th edition Pgno :1512-1514
1
Papillary
Adenocarcinoma
Squamous
Melanoma
Anatomy
G.I.T
e96fe0ba-1b84-4d97-93e3-73def80a6f04
single
Hereditary angioneurotic edema is due to ?
Ans. is 'a' i.e., Deficiency of C1 inhibitor Hereditary angioneurotic edema is due to C1inhibitor (Ci esterase inhibitor) deficiency.
1
Deficiency of C1 inhibitor
Deficiency of NADPH oxidase
Deficiency of MPO
Deficiency of properdin
Microbiology
null
9ed3502c-7221-40d5-a4d2-2bdedadbc09e
single
Patau syndrome due to -
null
2
Trisomy 21
Trisomy 13
18 P
Trisomy 18
Pathology
null
e9c17446-2ef3-4c5a-b05d-028d40514cf1
single
Traveller's diarrhea is caused by:
Ans. (c) ETECRef: Microbiology by Atianthanarayan and Paniker 8th Ed. / 276 & 277* Hemoltic uremic syndrome (HUS) is a type 3 hypersensitivity reaction associated with small vessel vasculitis.* Organisms causing HUS is E.Coli (particularly EHEC) and shigella dysentriae.
3
EIEC
EPEC
ETEC
EHEC
Microbiology
Enterobecteriaceae
d9026a71-1f2c-4c67-a3d3-02f0949b144f
single
Investigation of choice for myasthenia gravis?
Ans. (a) Single Fiber E.M.GRef: Harrison 19th ed. / 442e-6* Single fiber E.M.G is the investigation of choice for myasthenia gravis and shows a decremental response* Anti-acetylcholine receptor blocking antibody TITER is the most specific test for diagnosis of myasthenia gravis. Also remember that Tensilon test is a sc...
1
Single Fiber E.M.G
Muscle biopsy
Nerve conduction velocity
Anti -acetylcholine receptor antibody
Medicine
C.N.S.
e07e9372-e8e6-460e-b1b5-36eb251eace2
single
Treatment of choice for 3rd degree hemorrhoids is: September 2007
Ans. C: Hemorrhoidectomy External hemorrhoids develop around the rim of the anus. External hemorrhoids cause most of the symptoms associated with hemorrhoids (pain, burning, and itching) because the skin around them is very sensitive. If an external hemorrhoid becomes strangulated, a clot can form in it and become an e...
3
Sclerotherapy
Band ligation
Hemorrhoidectomy
All of the above
Surgery
null
7e82455b-71d2-48b5-b06b-3a5581984af8
multi
Which of the following can replace N2O as O2 carrier
Xenon has a very low blood-gas solubility coefficient (0.115) and produces rapid induction of and emergence from anesthesia. Xe is not teratogenic, does not undergo biotransformation, and exes anesthetic and analgesic effects under normal atmospheric pressure conditions (1.0 MAC = 71%). Xe is derived from a paicle deca...
2
Argon
Xenon
Helium
null
Anaesthesia
General anaesthesia
9e0212d4-d8b1-4c07-a0ef-3232828e86a1
multi
A male 45 years old wants his missing teeth to be replaced. Intraoral examination reveals Kennedy class 4 edentulous maxillary arch. Impression is made with fast setting alginate. The setting time of the material is :
A slight modification in the W/P ratio or the mixing time can have marked effects on two important properties of the gel, tear  strength,  and  elasticity;  thus, the setting time is best regulated by the  amount of retarder added during  the  manufacturing  process.  Usually,  the  manufacturers  make both fast-settin...
1
1.5 to 3 min
3 to 4.5 min
3 to 4 min
2 to 4 min
Dental
null
e0e8a6e5-5e16-445b-ad84-ebb6542a632d
single
Golden color amniotic fluid is seen in :
Abnormal colors of amniotic fluid : Green : Meconium stained Golden yellow : Rh incompatibility Saffron(greenish yellow) : Postmaturity Dark brown(tobacco juic : IUD Dark colored : concealed accidental hemorrhage Reference: Dutta Textbook of Obstetrics 7th edition page 38
1
Rh incompatibility
Fetal Death
lUGR
Fetal distress
Gynaecology & Obstetrics
General obstetrics
e30a8542-fb12-4b86-8597-50917056e68b
single
All are oncogenic viruses except:
Ans: C (Human Metapneumovirus) Ref: Robbins and Cotran 'Pathologic Basis of Disease 8th Edition. Elsevier. 201. Pg 313.Explanation:Oncogenic RNA VirusesHuman T-Cell Leukemia Virus Type 1 - T-cell leukemia/lymphomaHepatitis C Virus - Hepatocellular Carcinoma Oncogenic DNA VirusesHuman Papillomavirus.Types 1. 2. 4 & 7 - ...
3
Hepatitis C
Ebstein Barr virus
Human Metapneumovirus
Papillomavirus
Pathology
Infectious Disease
f803757d-2b0b-47e2-8d99-cd2c4bcaeaeb
multi