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Following an upper respiratory infection, a 7 year old child develops multiple petechial hemorrhages over her entire body. Her mother takes her to the physician, who does a complete blood count, revealing marked thrombocytopenia. Which of the following diagnoses is most appropriate for this individual? | The process described is commonly called acute idiopathic thrombocytopenic purpura (ITP), even though the autoimmune basis has been clearly established (some authors use "immune thrombocytopenic purpura," so that the initials still work). The thrombocytopenia in this disorder appears to be secondary to splenic destruct... | 2 | Bernard-Soulier syndrome | Idiopathic thrombocytopenic purpura | Thrombasthenia | Thrombotic thrombocytopenic purpura | Medicine | null | b195b84c-f180-42e2-a35b-f4690c7c3c3f | single |
The following is true about Mycoplasma except | Ans. (b) Are sensitive to beta-lactam group of drugs Note: Doxycycline is drug of choice for mycoplasma. | 2 | Multiply by binary fission | Are sensitive to beta-lactam group of drugs | Can grow in cell free media | Requires sterols for their growth | Microbiology | null | 2014f954-dfbc-4947-8001-06cadea31ad6 | multi |
Drug which increases absorption of oral iron ? | Ans. is 'c' i.e., Vitamin C o Factors facilitating iron absorption - Acid, ascorbic acid (Vit C), amino acids containing SH radical, meat. | 3 | Folic acid | Nalidixic acid | Vitamin C | Tetracycline | Pharmacology | null | bb17c18a-be99-4d22-ac56-146a08455857 | single |
Which of the following sites is not involved in a posterior cerebral artery infarct - | null | 4 | Midbrain | Thalamus | Temporal lobe | Anterior Cortex | Medicine | null | 698fd3db-35af-4a09-b31d-8a932d6e9927 | single |
In HIV infected individual Gram stain of lung aspirate shows yeast like morphology. All of the following are the most likely diagnosis except ? | Ans. is `d' i.e., Aspergillus fumigates In this question the positive organism should fulfill the following two criteria: Causes lung infection in immunocompromised individual The organism should have a yeast like morphology Among the organism mentioned in the question Aspergillus fumigatus does not fulfill the above m... | 4 | Candida tropicalis | Cryptococcus neoformans | Pencillium marneffi | Aspergillus fumigates | Microbiology | null | 46b796a0-798f-4e43-8c38-129866490bf1 | multi |
A 65-year-old has suffered from essential tremor for many years. Her symptoms are exacerbated by stress and fatigue and some evenings she is unable to cook or make herself a cup of tea because of it. Which of the following is the most appropriate first-line treatment? | Generally essential tremor requires no treatment but if the quality of life is affected then Propranolol should be given. | 3 | Pramipexole | Topiramate | Propranolol | Diazepam | Medicine | Parkinsonism and other movement disorders | b4d01bcf-5f60-4888-8157-ae26f9fee499 | single |
Best chemical disinfectant to disinfect stethoscope: | Ans. A. Isopropyl alcoholMedical devices require disinfection as per Spaulding criteria of criticality according to degree of risk for infection involved in use of these items. Stethoscope is a non-critical device requiring intermediate-low level disinfectant. Isopropyl alcohol can be routinely used for disinfection of... | 1 | Isopropyl alcohol | Ethylene oxide | Halogenated compound | Plasma sterilization | Microbiology | General | 9e7eef9d-3a60-4d2e-921e-94316580776a | single |
A 28-year-old professional cyclist has been training for an oppounity to go for a long race. His coach strongly suggests the intake of carbohydrates after the work out to ensure a muscle glycogen storage. The activity of muscle glycogen synthase in resting muscles is increased by the action of which of the following: | Insulin increases the activity of muscle glycogen synthase after the intake of carbohydrates & increases glycogen reserves in liver & muscles. Insulin is anabolic hormone, so increases the rate of the anabolic pathway - glycogenesis. Fig.: In fed state, insulin hormone is released | 3 | Epinephrine | Glucagon | Insulin | Phosphorylation | Biochemistry | Four Formulas | f68c02a6-0a84-4835-a336-b700b7959889 | single |
Xerophthalmia is a public health problem if prevalence of bitot spots is | Night blindness : > 1%.
Bitot spots : >0.5%.
Corneal ulcer : >0.05%.
Corneal xerosis : >0.01%. | 2 | > 1% | >0.5% | > 0.01% | > 0.05% | Medicine | null | a96fcd83-9da5-4605-96a3-b3bbd6505e8c | single |
Tumour having a "Swiss cheese appearance" is | Histologically Adenoid cystic carcinoma shows swiss cheese appearance with cribriform growth. | 4 | Pleomonphic adenoma | Rhabdomyosarcoma | Basal cell carcinoma | Adenoid cystic carcinoma | Ophthalmology | null | 0ea6a68d-620c-4855-9667-4a470f086ac0 | single |
Which of the following drugs shown in the graph below has highes potency? | Drug potency and efficacy | 1 | Drug A | Drug B | Drug C | Both Drug A and | Pharmacology | NEET Jan 2020 | 647d0a37-362c-41f3-9e10-9445d5d6530f | multi |
Interstitial cells (of Leydig) in testes secrete which of the following:March 2011 | Ans. B: TestosteroneLeydig/Interstitial cells secrete androgenic hormone testosterone at the time of pubeyPrimary cell types of testes(A). Within the seminiferous tubules- Here, germ cells develop into spermatogonia, spermatocytes, spermatids and spermatozoon through the process of spermatogenesis. The gametes contain ... | 2 | nhibin | Testosterone | Anti-mullerian hormone | Aromatase | Physiology | null | 0e50781c-e803-4c53-a1e7-77a28be28a42 | single |
Which of the following fluoroquinolones does not require dose adjustment in a patient with creatinine clearance of < 50 mg/min ? | null | 2 | Ciprofloxacin | Trovafloxacin | Lomefloxacin | Sparfloxacin | Pharmacology | null | 4d77819e-ccbb-45ca-a10c-a6a1eb003171 | single |
A 4-year child presented with fever for 6 days, generalized rash and cervical lymphadenopathy with strawberry tongue. What could be the diagnosis? | Ans-B | 2 | Scarlet fever | Kawasaki disease | Kimura disease | Rosai dorfmann's disease | Unknown | null | c139f386-7593-40d3-b4ca-4d707b85e077 | single |
Skin pigmentation & Icthyosis like side effects are seen in | Ichthyosis - Fish like scaling (d/t severe dryness in patient) - Causing skin to break Two types - Congenital Acquired I.vulgaris - Autosomal Dominant, MC type Deficiency - Filaggrin Involves Extensors Leprosy - Involvement of ANS No sweating - dry skin X linked ichthyosis - X-linked Recessive defect with steroid sulph... | 2 | Rifampicin | Clofazimine | Dapsone | Steroid | Dental | Hyper Pigmented Disorders | ca917c79-1dbe-4c64-bc4e-dd553b75f49f | single |
Methicillin resistant staphylococcus aureus is not expected to respond to: | CARBAPENEMS: lmipenem It is an extremely potent and broad-spectrum Beta-lactam antibiotic whose range of activity includes grampositive cocci, Enterobacteriaceae, Ps. aeruginosa, Listeria as well as anaerobes like Bact. fragilis and Cl. difficile. It is resistant to most Beta-lactamases; inhibits penicillinase producin... | 4 | Aminoglycoside | Lincosamide | Oxazolidinone | Carbapenem | Pharmacology | Chemotherapy | 7b367525-42d4-416c-a5c3-a188f10038e2 | multi |
Most common tumor of submandibular gland is - | Ans. is 'a' i.e., Pleomorphic adenoma * Pleomorphic adenoma - Most common benign tumor of submandibular gland* Adenoid cystic carcinoma - Most common malignant tumor of submandibular gland. | 1 | Pleomorphic adenoma | Adenolymphoma | Oncocytoma | Hemangioma | ENT | Oral Cavity | c2f394f5-b98f-4905-babb-e4d401b34f60 | single |
Which of the following acts at site A? | Ans. B. VorapaxarVorapaxar does not affect ADP-mediated platelet aggregation, coagulation parameters, or bleeding time.A. Protease-activated receptor-1 (PAR-1) antagonists-VorapaxarB. Adenosine diphosphate (ADP) receptor inhibitors - Ticlopidine, Clopidogrel, Prasugrel, TicagrelorC. Glycoprotein IIB/IIIA inhibitors -Ab... | 2 | Aspirin | Vorapaxar | Abciximab | Ticagrelor | Pharmacology | Hematology | 1e59cb85-9f70-4170-9f59-b731fb352cf4 | single |
Rheumatoid arthritis commonly affects the - | Ans. is 'a' i.e., Cervical spine o In decreasing frequency, the metacarpophalangeal (MCP), wrist, proximal interphalangeal (PIP), knee, metatarsophalangeal (MTP), shoulder, ankle, cervical spine, hip, elbow and temporomandibular joints are most commonly affected. | 1 | Cervical spine | Thoracolumbar spine | Lumbar spine | Sacral spine | Medicine | Rheumatoid Arthritis | 85a6148c-a91d-4df4-83da-f096183820fc | single |
Which of the following is the presenting pa in the fetus in left occiputo - anterior (LOA) position: | In Left occiput anterior (LOA) position, the head is flexed sharply so that the chin is in contact with the thorax. The occipital fontanelle is the presenting pa, and this presentation is referred to as a veex or occiput presentation. If Fetal head is - Well flexed - Veex presentation Deflexed head - Brow presentation ... | 4 | Shoulder | Face | Brow | Veex | Gynaecology & Obstetrics | Labour - normal, abnormal, malposition, malpresentation and their management | 5b24517e-41af-4ff3-9838-339a82ffb854 | single |
The drug most likely to be responsible for acute pancreatitis is: | * Didanosine is most commonly implicated anti-retroviral drug in causing acute pancreatitis. * Maximum chances of peripheral neuropathy are seen with stavudine. * Minimum risk of peripheral neuropathy is seen with Lamivudine. * Abacavir predisposes to MI. | 1 | Didanosine | Ketoconazole | Saquinavir | Zidovudine | Pharmacology | Anti-HIV Drugs | 77df41a2-9fa0-4913-8457-286e96e60088 | single |
Nervus spinosus is a branch of which of the following? | The meningeal branch or nervus spinosum enters the skull through the foramen spinosum with middle meningeal aery and supplies the dura mater of middle cranial fossa. NOTES: The branches of mandibular nerve- a.Meningeal branch or nervous spinosum b.Nerve to medial pterygoid From anterior trunk; a.Sensory branch,the bucc... | 2 | Maxillary nerve | Mandibular nerve | Facial nerve | Nerve of pterygoid canal | Anatomy | Head and neck | a33c910a-3e89-480b-b2f6-550d02fa2f6c | single |
A patient Geeta began taking alendronate and she was advised to take large amount of water and remain in the standing position for at least half an hour till she had the first meal of the day. These instructions were given to reduce the risk of: | Due to risk of Erosive Gastritis Bisphosphonates are advised to be taken :- - with plenty of water - remain in standing position - before first meal of day | 3 | Cholelithiasis | Constipation | Erosive esophagitis | Osteonecrosis | Pharmacology | Gastro-Intestinal Tract | 39010f05-2d63-4eb7-9361-d7ea301dd36a | single |
Cyanides shows its toxicity by binding to the following: | Cyanide is a chemical asphyxiant; binding to cellular cytochrome oxidase, it blocks the aerobic utilization of oxygen. Whole-blood levels higher than 0.5-1 mg/L are considered toxic. The conventional cyanide antidote package consists of amyl and sodium nitrites, which produce cyanide-scavenging methemoglobinemia, and s... | 1 | Cytochrome oxidase | Acetylcholinesterase | Alpha adrenergic receptors | Histamine | Forensic Medicine | null | a136e8cd-6d02-4ce5-8f46-81df5c3aab25 | single |
Submucosal plexus of GIT | Two major networks of nerve fibers are intrinsic to the gastrointestinal tract: the myenteric plexus (Auerbach's plexus), between the outer longitudinal and middle circular muscle layers, and the submucous plexus (Meissner's plexus), between the middle circular layer and the mucosa. Collectively, these neurons constitu... | 3 | Myenteric plexus | Auerback's plexus | Meissner's plexus | Extrinsic nerves | Physiology | G.I.T | 9da6df98-ef08-4fce-82cb-969f44cfb23f | single |
All have antioxidant propey except ? | Ans. is 'c' i.e., Phosphorylase There are two types of antioxidant systems :? 1. Enzymatic antioxidant system This include Catalase Superoxide dismutase (SOD) Glutathione peroxidase 2. Non-enzymatic antioxidant system This is fuher subdivided into Vitamins : Vitamin E, Vitamin A & beta carotene, Vitamin C. Minerals : S... | 3 | Catalase | Glutathione peroxidase | Phosphorylase | Superoxide dismutase | Biochemistry | null | efa9917b-5993-4591-a626-2979e1002732 | multi |
A 30 year old man has 6/5 vision each eye, unaided. His cycloplegic retinoscopy is +1.0 D sph. at 1 metre distance. His complaints are blurring of newsprint at 30 cm, that clears up in about 2 minutes. The most probable diagnosis is: | Ans. (c) Accommodative inertiaOption a- (Correction factor for distance (d) from which retinoscopy is done D=d1 Thus, for the patient, there is no refractory error.Option b- Presbyopia usually occurs at around 40 years of age, due to physiological insufficiency of accommodation, can not clear in 2 minutesOption d- cycl... | 3 | Hypermetropia | Presbyopia | Accommodative inertia | Cycloplegia | Ophthalmology | Elementary Optics | e79a781a-0d36-4f23-aa72-0b499aaeaf8e | single |
Trismus is seen in commonly ? | Ans. is 'b' i.e., Quinsy Trismus is inability to open-mouth. Normal opening of mouth ranges between 25-50mm. Any value less than this is known as trismus (roughly the opening should permit a minimum of three fingers when inseed sideways). Causes of quinsy are :? A. Common causes Infection around impacted third molor Qu... | 2 | Ludwig angina | Quinsy | Retropharyngeal abscess | Parapharyngeal abscess | ENT | null | 926b5332-4414-4328-9fdd-53669fa7bfeb | single |
Theory of web of causation was given by? | ANSWER: (A) Me Mohan and PughREF: Park 20th edition page 32"The web of causation theory was given by MC Mohan and Pugh" | 1 | Me Mohan and Pugh | Pettenkoffer | John snow | Louis Pasteur | Social & Preventive Medicine | Concept of disease causation | 46478793-f18c-41a3-93c0-2fd891bafbbc | single |
Most potent cardiac stimulant of the following is ? | Ans. is 'a' i.e., Adrenaline | 1 | Adrenaline | Noradrenaline | Ephedrine | Salbutamol | Pharmacology | null | 4ebbae78-82b0-4954-a8bb-64abfe9c9957 | single |
Which of the following is not included in Class I cavity preparation? | All preparations required to treat pit-and-fissure caries are termed Class I preparations.
These include preparations on
Occlusal surfaces of premolars and molars.
Occlusal two thirds of the facial and lingual surfaces of molars, and
The lingual surfaces of maxillary incisors.
Preparations required to correct caries ... | 4 | On occlusal surfaces of premolars and molars | On occlusal two thirds of the facial and lingual surfaces of molars | On the lingual surfaces of maxillary incisors | On occlusal cusp tips of posterior teeth | Dental | null | 327646b7-fdf7-4700-9485-4e82249ec38d | single |
Which one of the following statements regarding collagen is true? | Collagen is composed of closely packed Tropocollagen Molecules. Reticular Fibers are composed of type III collagen, Elastic Fibers are composed of Elastin microfibrils rather than collagen. Collagen is synthesized by Fibroblasts not mast cells. | 1 | It is composed of Tropocollagen. | Reticular Fibers are composed of type II collagen. | It is synthesized mostly by Mast cells. | Elastic Fibers are composed of type IV collagen. | Anatomy | Glands & Connective tissue | 297e977c-9b07-483c-9b63-24808104c3a3 | multi |
Most commonly associated human papilloma virus with Cancer Cervix is? | ANSWER: (A) HPV 16REF: Robbins 7th edition page 324Repeat in December 2011, See APPENDLX-31 for "HUMAN PAPILLOMA VIRUS""HPV 16 and 18 and less commonly HPV 31, 33, 35, 51 are found in approximately 85 % of invasive squamous cell cervical cancer" | 1 | HPV 16 | HPV 24 | HPV 32 | HPV 36 | Pathology | Female Genital Tract | 24b110cc-b516-4f1f-820c-5b1ed9cf335b | single |
Most popular theory is the | null | 1 | Hydrodynamic theory | Direct nerve stimulation | Transduction Theory | All are equally popular | Dental | null | f3d7dd7c-4faf-47de-98fa-e5314dda4d58 | multi |
Gallstones may be complicated by which of the following? 1. Pancreatitis 2. Choledocholithisasis 3. Acute cholecystitis 4. Carcinoma stomach 5. Carcinoma pancreas | Effects and complications of gallbladder stones are: In Gallbladder In Bile ducts In the intestine Silent stone Acute cholecystitis Chronic cholecystitis Mucocele Empyema Perforation Gangrene Carcinoma Obstructive jaundice Cholangitis Acute pancreatitis Acute intestinal obstruction (Gallstone ileus) Ref: Bailey & Love ... | 1 | 1,2 & 3 | 2,3 & 4 | 1,3 & 5 | 2,3 & 5 | Surgery | null | 765baade-a431-494a-b657-87ff3fe32bd2 | multi |
Ventral mesogastrium derivatives include all EXCEPT: | - Gastrosplenic ligament develops in dorsal mesogastrium. Structures derived from ventral mesogastrium:- Liver Ventral pancreatic bud Right and Lefttriangular ligaments Coronary ligaments of liver Falciform ligament of liver Lesser omentum Structures derived from dorsal mesogastrium:- Spleen Dorsal pancreatic bud Gastr... | 4 | Falciform ligament | Coronary ligament | Lesser omentum | Gastrosplenic ligament | Anatomy | Mesentry, neurovascular bundle | 01c46368-9145-4c6e-bb5b-05abb1fd4775 | multi |
The drug not used in acute asthma is | Refer KDT 6/e p 222 Only bronchodilator drugs are useful for the treatment of acute attack of asthma Beta 2 agonists eg salbutomol, terbutaline. Antichokinergics eg Iprqtropoum, tiotropium Methylxanthine eg Theophylline | 3 | Salbutomol | Ipratropium | Montelukast | Hydrocoisone | Pharmacology | Respiratory system | 0f203f3e-a0ca-4b52-8efb-cf903ed16e31 | single |
Category 7 on biomedical waste management contains | Ans. (b) Solid wasteCat. BMWWASTES INCLUDED1.Human Anatomical WasteHuman tissues, organs, body parts2.Animal wasteAnimal tissues, body parts,organs,carcasses, fluids, blood3.Microbiology & biotechnology wasteWaste from lab cultures,stocks,specimens of microorganisms, vaccines,cellcultues,toxins, wastes from production ... | 2 | Soiled waste | Solid waste | Liquid waste | Incineration ash | Social & Preventive Medicine | Environment and Health | 3ff38f5e-aa7b-42c1-b387-208ac562585f | single |
Which of the following is a device of radiation dose measurement? | The ionization chamber is the simplest of all gas-filled radiation detectors, and is widely used for the detection and measurement of certain types of ionizing radiation; X-rays, gamma rays, and beta particles. | 2 | Storage phosphor plate | Ionization chamber | Coolidge tube | Charged couple devices | Radiology | null | bcf54921-e914-46da-b50f-fee0dcd02e53 | single |
Indusium griseum is found in: | Ref: Grays Anatomy, 40th edExplanation:Indusium griseum is a thin strip of grey matter found on the dorsal surface of the corpus callosumThe insula is a cortical region hidden within the depths of the lateral fissure by overhanging parts (opercula) of the frontal, parietal and temporal lobes. A complex of gyri on the m... | 4 | Association fibres of corpus callosum | Lateral fibres of corpus callosum | Medial fibres of corpus callosum | Dorsal surface of corpus callosum | Unknown | null | 8f18c4d9-1026-4302-abf3-5108b5a6b443 | multi |
Killing power of disease is | Ans. b (Case fatality rate). (Ref. Park, PSM, 17th ed., 52, 88)- CFR is measurement of killing power of a disease.Secondary attack rate =Number of exposed persons developing the disease within the range of IP------------------------------------------Total number of exposed/"susceptible" contactsx 100- The primary case ... | 2 | Secondary attack rate | Case fatality rate | IMR | MMR | Social & Preventive Medicine | Concept of Health and Disease | 6d6ee4d6-7161-45f6-81a1-fc68754926be | single |
Carbon steel instruments and BURS are best sterilized by: | Carbon steel instruments and burs do not rust, corrode, or lose their temper or cutting edges if they are well-sterilized by dry heat and chemiclave. | 2 | Autoclave | Dry heat and chemiclave | Boiling water | 2% glutaraldehyde solution | Dental | null | aa5e4be4-4da1-49a9-8188-76886e2e1aed | single |
Which of the following is not used for intravascular volume maintenance is: | Ans. (c) ErythropoetinRef: Crystalloids versus colloids in fluid resuscitation: a systematic review. Crit Care Med.* Colloids increase intravascular volume* Colloids are dextran, gelatin, hydroxyethyl starch. | 3 | Hydroxy ethyl starch | Dextran | Erythropoetin | Gelatin | Surgery | Fluid & Electrolyte | 789cb378-171c-454d-be28-9ece4a8d708c | single |
The synthesis of one peptide bond involves hydrolysis of | During the translation process, the formation of one peptide bond (adding one amino acid) consumes 4 high energy phosphates (2 from ATP & 2 from GTP). Eukaryotes will add 6 amino acids and prokaryotes will add 18 amino acids per second. (Refer: Harper's Illustrated Biochemistry, 26th edition, pg no: 370) | 2 | 1 ATP & 3 GTP | 2 ATP & 2 GTP | 3 ATP & 1 GTP | 4 ATP | Anatomy | All India exam | 7c94d6e9-f0c9-434e-8c3a-cc17159554da | single |
In which of the following the 3 point relationship is maintained: | Ans: d (Supracondyar)The 3 point relationship is maintained in supracondylar fracture humerus.The 3 bony points are:Medial epicondyleLateral epicondyleTip of olecranonHead of radius is sometimes considered as the fourth partNormally in an elbow flexed to 90deg. these three bony points form a near isoseles triangle. But... | 4 | medial condyle humerus | lateral condyle humerus | olecranon | Supracondylar | Orthopaedics | Injuries Around Arm & Elbow | d77c59bc-05c3-483e-9cda-bc4da8b9c052 | single |
According to the congenital rubella syndrome eradication program, the first priority for rubella vaccination is offered to which of the following group? | The first and foremost priority has been given to the group of all non-pregnant women between the ages 15 and 34 for rubella vaccination. The other three options are suitable age groups. Ref: Park's Textbook of Preventive and Social Medicine 19th edition; pages 130 - 131. | 3 | All female children at one year | All non pregnant women | All non pregnant women of age 15 to 34 | All adolescent non pregnant girls 15 to 24 years of age | Social & Preventive Medicine | null | 268136b3-b9d5-4d55-aa1d-e811f92d9712 | multi |
A baby presenting with multiple deformities, cleft lip, cleft palate, microcephaly, small eyes, scalp defect and polydactyly, seen in which syndrome- | Ans. is 'a' i.e., Trisomy 13 | 1 | Trisomy 13 | Trisomy 18 | Trisomy 21 | Monosomy 2 | Pediatrics | null | c65bb252-8f15-479a-b281-c256696048b8 | multi |
Which of the following is NOT known as adverse drug reaction of furosemide? | Toxicity of frusemide includes: Hypokalemic metabolic alkalosis Ototoxicity Hyperuricemia Hypomagnesemia Allergic and other reactions Ref: Katzung, 11th edition, Chapter 15. | 1 | Hyperkalemia | Acidosis | Hyperuricemia | Hypomagnesemia | Pharmacology | null | b57598eb-6f84-48df-88bb-faaae5a57694 | single |
The last tributary of the azygos vein is - | Tributaries of Azygos vein
Right superior intercostal vein
Right posterior intercostal veins (5 to 11)
Hemiazygos vein
Accessory hemiazygos vein
Right bronchial vein- last tributary that joins Azygos vein just before its termination.
Esophageal, mediastinal and pericardial veins. | 3 | Right superior intercostal vein | Hemi-azygos vein | Right bronchial vein | Accessory azygos vein | Anatomy | null | 594abb46-bc36-4ba4-9e34-fff7a0639d90 | single |
Benefits of breast milk are - | It fully meets the nutritional requirements of the infant in the first few months of life.REF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.496- | 1 | Better nutrition | Less infection | More diarrhea | Less allergy | Social & Preventive Medicine | obstetrics,pediatrics and geriatrics | 790bfa01-9b88-4a2b-a095-8dd2743b2831 | multi |
True about p53 - | Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice). This homolog (o... | 1 | Tumor suppressor gene | Proapoptotic | Arrest cell cycle in | Protooncogene | Pathology | General pathology | 2cdd7e70-8ba5-4e17-ad28-1ffb2570bc4c | multi |
Denominator of positive predictive value is ? | Ans. is 'b' i.e., True positive + False positive | 2 | True positve + False positive | True positive + False negative | False positive + True negative | False positive + False negative | Social & Preventive Medicine | null | 52bb0d77-e709-43d3-bf6f-86f10e7c042f | multi |
Gastrointestinal stromal tumours arise form | Gastrointestinal stromal tumours (GISTs) may arise in anypa of the gastrointestinal tract but 50% will be found inthe stomach.They are now known to be a distinct tumor derived from the interstitial cells of Cajal,The tumours are universally associated with a mutation in thetyrosine kinase c-kit oncogene (CD 117). These... | 4 | Paneth cells | Stave cells | Enterocytes | Interstitial cells of Cajal | Surgery | G.I.T | b81eca00-33ac-4418-8320-6dbd7e616223 | single |
Infection with HIV is associated with atrophy in all of the following parts of the brain except: | Ans. a. Anterior cingulate gyrus (Ref: Harrison 19/e p1264, 1265, 18/e p1559, 1560, 3427)AIDS causes subcortical dementia, involves white matter and causes progressive multifocal leukoencephalopathy and main feature is demyelination.Overall cerebral atrophy and prominent caudate region atrophy are important radiographi... | 1 | Anterior cingulate gyrus | Globus pallidus | Caudate nucleus | Lower white matter volume | Medicine | Virology | 5503fa59-6c90-4be1-9994-2424bf0284c9 | multi |
Dialysis is not indicated in toxicity of: | null | 4 | Lithium | Methanol | Salicylates | Digitalis | Pharmacology | null | 2d1f51ba-acc2-4f16-b2ba-ccb2b0bdbc93 | single |
The recommended concentration of free chlorine is | The chlorine demand of water is the difference between the amount of chlorine added to the water and the amount of residual chlorine remaining at the end of a specific period of contact (usually 60 min)The point at which chlorine demand of water is met is called the &;breakpoint chlorine&;Chlorine added beyond breakpoi... | 2 | 0.2mg/dl | 0.5mg/dl | 5mg/dl | 10mg/dl | Social & Preventive Medicine | Environment and health | 521785c7-ebc4-4bc8-bc9f-42c67d0481ae | single |
All are features of lepromatous leprosy except | Features of lepromatous leprosy bilaterally symmetrical lesion - macules papules,plaques,nodules or nerves glove and stocking aneathesia madarosis-loss of eyebrows and eyelashes leonine fancies nodular lesions over nose and hard palate ,tongue. nasal stuffiness and epistaxis saddle nose autoamputation of fingersand toe... | 2 | Saddle nose | Ulcus serpens | Gynecomastia | Madarosis | Dental | Bacterial infections | 3cd80830-91ed-4c1f-850f-35925c6a4e9d | multi |
Trans ovarian transmission is seen among: | Transovarial or transovarian transmission- transmit pathogens from parent ahropod to offspring ahropod. Rickettsia rickettsii, carried within ticks, is passed on from parent to offspring tick by transovarial transmission Occurs also in aedes mosquito vector of the yellow fever virus and in phlebotomine sandflies that t... | 2 | Rickettsia akari | Rickettsia rickettsii | Rickettsia prowazekii | Rickettsia typhi | Microbiology | Systemic Bacteriology (Haemophilus, Yersinia, Spirochaetes, Ricketssia, Chlamydia, Mycoplasma and Miscellaneous Bacteria) | 5bdb03c1-21c8-4c8d-9f5b-7ddbaef3722c | single |
The coupling agent between electrical excitation and contraction of a muscle is said to be: | Coupling: electrical excitation travels into muscle, releases calcium & this calcium combines with troponin & causes muscle contraction. Events tills the release of calcium is electrical & after that is mechanical. T tubules contain DHPR & L tubules contain RYR. | 3 | Dihydropyridine receptor (DHPR) | Ryanodine receptor | Ca++ | Troponin C | Physiology | Muscle | c77934b8-292d-4c22-93cb-1dbd032652b6 | single |
Which cholesterol is designated as "Good Cholesterol" - | Ans. is 'c' i.e., HDL o The level of HDL in serum is inversely related to the incidence of MI.o As it is "antiatherogenic" or "protective" in nature, HDL is known as "good cholesterol"..ChylomicronVLDLLDLHDLElectrophoresisFound at originPre-b (a2)ba (or a1)Mobility in electric fieldLeast Found in beta regionHighestApor... | 3 | VLDL | LDL | HDL | IDL | Biochemistry | Cholesterol and Lipoproteins | 66961111-70fb-4ba2-a9fe-5adac425481f | single |
All of the following statements about paclitaxel are true EXCEPT: | TAXA N E S Paclitaxel It is a complex diterpin taxane obtained from bark of the Western yew tree, which exes cytotoxic action by a novel mechanism. It enhances polymerization of tubulin: a mechanism opposite to that of vinca alkaloids. The microtubules are stabilized and their depolymerization is prevented. This stabil... | 1 | It is obtained from E. coli | It acts by enhancing the polymerization of B-tubulin | It can cause bone marrow suppression | It is used in ovarian and breast cancer | Pharmacology | Chemotherapy | 374854cb-6156-448d-8546-69bc235483fe | multi |
In diffuse calcification of pancreas calcium lies in- | null | 4 | Acinar tissues | Interstitium | Pancreatic ducts | Any where | Pathology | null | b0c138ab-82ad-484d-8b00-4dec3c4b6a80 | single |
Which of the following facts are false regarding Barrett's esophagus? | Barrett esophagus is well recognized as a complication of gastroesophageal reflux disease (GERD). Prolonged exposure of the esophagus to the refluxate of GERD can erode the esophageal mucosa, promote inflammatory cell infiltrate, and ultimately cause epithelial necrosis. This chronic damage is believed to promote the r... | 4 | Premalignant | More common in men | Established metaplasia doesn't reverse | null | Surgery | null | 39d9139b-5857-41e4-bf32-5322a63b9e22 | multi |
Evaluation of an infant reveals hypocalcemia due to a lack of parathyroid hormone. On x-ray, the thymic shadow is absent. Which of the following embryonic structures is involved | Since thymus is missing, appropriate answer would be third pharyngeal pouch. This patient has got DiGeorge syndrome. DiGeorge syndrome causes migration defects of neural crest-derived tissues, paicularly affecting development of the third and fouh Branchial pouch (pharyngeal pouches) | 3 | Third pharyngeal cleft | Fouh pharyngeal cleft | Third pharyngeal pouch | Fouh pharyngeal pouch | Anatomy | All India exam | 1f09fb1f-b028-42dc-9d7e-63c21f2949a5 | single |
Which of the following is active against atypical mycobacteria? | Clarithromycin: The antimicrobial spectrum of clarithromycin is similar to erythromycin; in addition, it includes Mycobact. avium complex (MAC), other atypical mycobacteria, M.leprae and some anaerobes but not Bact.fragilis. It is more active against sensitive strains of gram-positive cocci, Moraxella, Legionella, Myco... | 4 | Clarithromycin | Rifabutin | Ciprofloxacin | All of the above | Pharmacology | Chemotherapy | 8c8d41d8-048d-498f-96fd-f2ae29967f02 | multi |
Prognosis in a case of duodenal perforation is determined by all except | null | 3 | Age of the patient | Duration of history | Basal pneumonia | Peritonitis | Surgery | null | 6c815a3d-b7d2-4de3-a579-ee8f4bd343e2 | multi |
Temporary hardness of water is primarily due to the presence of | Temporary hardness (Carbonate hardness) due to Calcium & Magnesium salts of Bicarbonates. | 3 | Calcium and magnesium sulphates | Calcium and magnesium chlorides | Calcium and magnesium bicarbonates | Calcium and magnesium nitrates | Social & Preventive Medicine | null | 3011674e-110b-4386-b701-16744e43e6d5 | single |
Notochord develops into? | As the embryo enlarges,the notochord elongates considerably and lies in the midline,in the position to be later occupied by the veebral column. However ,the notochord doesn't give rise to the veebral column.most of it disappears,but pas of it persists in the region of each interveebral disc as the nucleus pulposes HUMA... | 3 | Annulus fibrosus | Dorsal root ganglia | Nucleus pulposus | Veebral body | Anatomy | General anatomy | 84a8dd2d-2b59-44ab-ae32-8ecb11e11a73 | single |
This Hand Radiograph of a 2 year old Child with Dwarfism suggest the diagnosis of: | The Hand Radiograph demonstrates widening of metacarpals with proximal pointing of metacarpals from index to little finger suggestive of Moriquos syndrome an autosomal recessive Mucopolysaccharoidosis type IV. Proximal pointing of metacarpals is also a feature of Hurlers syndrome another autosomal recessive Mucopolysac... | 1 | Morquio syndrome | Achondroplasia | Hyperparathyroidism | Hypothyroidism | Radiology | Musculoskeletal Radiology | 94e0e763-4cf0-45ea-b86a-d407361ad39e | single |
In aificial rupture of membrane , fetal hea shows : | Variable deceleration | 3 | Acceleration | Deceleration | Variable deceleration | Any of the above | Gynaecology & Obstetrics | null | 32c2c0d8-b1c6-4ed2-9fc4-4f8324d137af | multi |
Main enzyme involved in digestion of fatty food- | Ans. is 'c' i.e., Pancreatic lipase o Ebner's glands on the dorsum of the tongue secrete lingual lipase and the stomach also secretes a lipase (gastric lipase}.o However, they are of very little significance in fat digestion.o Fat digestion essentially begins in the duodenum with entry of pancreatic and biliary secreti... | 3 | Lingual lipase | Gastric lipase | Pancreatic lipase | Phospholipase | Physiology | Digestion and Absorption | d92332ef-8c20-4bdc-ac9d-8b69dcf4a105 | single |
A 9 months old girl is presented with PR bleed, vomiting, mass & colicky pain in Rt lumbar region with masked liver dullness. She is in shocklike condition. Management should includes | .Intussusception Mostly between 6-11 months of age Features:intermittent colicky abdominal pain,vomiting,bloody mucous stools(current jelly) History of recent change of milk formula,upper respiratory tract infection,vaccination may be present. Sausage shaped mass maybe palpable on right quadrant of abdomen...iliac foss... | 1 | Barium enema | Saline reduction | Give O2 | Nasogastric tube | Pediatrics | Gastrointestinal tract | 73829694-f73d-4a87-a101-7b7a29a87c18 | single |
Acridine orange is a fluorescent dye used to bind | DNA and RNA Acridine orange is a nucleic acid selective metachromatic stain useful for cell cycle determination Acridine orange interacts with DNA and RNA by intercalation or electrostatic attraction respectively - DNA intercalated Acridine orange fluoresces green - RNA electrostatically bound acridine orange fluoresce... | 1 | DNA and RNA | Protein | Lipid | Carbohydrates | Biochemistry | null | 381e8ace-898f-4262-b56a-1f5c2335afac | single |
Lepromin test is used for all of the following except- | Ans. is 'd' i.e., Diagnosis of leprosy | 4 | Classify the lesions of leprosy patients | Determine the prognosis of disease | Assess the resistance of individuals to leprosy | Diagnosis of leprosy | Social & Preventive Medicine | null | 2cfd968d-f55f-4420-a94a-7f40d4f2e847 | multi |
Acidic property to a-carbon of amino acid is due to- | Ans. is 'a' i.e., Carboxyl groupo The acid base properties of amino acids depend on the amino and carboxyl groups attached to the a-carbon.i) The carboxyl (-COOH) group of an amino acid can donate protein (H+) and behave as an acid forming a negatively charged anion (COO-).ii) Amino group (-NH2) can accept proton (H+) ... | 1 | Carboxyl group | Amino group | Hydrogenatom | null | Biochemistry | Amino Acids Basics | f762e5ee-e7c4-4948-9ea5-c0ddd0f4b6b1 | multi |
Shortest fetal skull diameter is | Ans: A (Bimastoid) Ref: Dana textbook of obstetrics 5th ed pg 85Explanation: (See the following figure and table) | 1 | Bimastoid | Submentovertical | Submentobregmatic | Occipito-fronta! | Gynaecology & Obstetrics | Fetal Skull and Maternal Pelvis | 5bab4c84-c6db-46a9-bc47-825e33eb3816 | single |
Xeroderma pigmentosum is produced as a result of a defect in | It is derived from the Greek terms xeres = dry and derma = skin. It is an autosomal recessive condition. Defect lies in the NER (nucleotide excision repair) mechanism. There are seven XP genes (A to G) necessary for NER mechanism in humans. Mutation in any one of them may lead to the condition XP. UV light (sun light) ... | 4 | DNA polymerase III | DNA polymerase II | DNA exonuclease | DNA ligase | Biochemistry | nutrition and digestion | b90b0cf4-5c14-4e9a-b988-469b3ab620ef | single |
Contrecoup injury is seen in - | null | 1 | Head injury | Spinal injury | Hand injury | Abdominal injury | Forensic Medicine | null | 4908c650-8082-48e5-9b70-6e92eac845e0 | single |
Actinomycosis is characterized by all except | There is no Lymph node involvement in Actinomycosis. | 1 | Lymphadenopathy | Discharging sinus | Pyaemia | Honey comb liver | Surgery | null | ae31076a-66cb-4af3-835b-b967bde2f374 | multi |
Which of the following medication is associated with an Increased risk of agranulocytosis? | The most impoant side effect of cloxazapine is agranulocytosis. All the other given drugs donot have agranulocytosis as side effect. Ref: KD TRIPATHI 8TH ED. | 1 | Clozapine | imipramine | Lithium | Haloperidol | Pharmacology | Central Nervous system | b4d464f9-01df-427e-8c6f-cdc33dbff0df | single |
Heimlich manoeuvre is indicted for:- | Heimlich manoeuvre is a first aid procedure used to treat choking or upper airway obstructions by foreign objects. The term Heimlich manoeuvre is named after Dr. henry Heimlich. | 3 | Near drowning | Wet drowning | Choking | Gagging | Forensic Medicine | Asphyxial deaths | e8c7b774-997d-419b-b648-749fb3d9344a | single |
After applying a statistical test, an investigator gets the `p value' as 0.01. It means that: | The difference is not sigificant 1% times and significant 99% times [Ref Park, I8/e, p 650-6511 Repeat May 2005 While comapring two samples first we set up a hypothesis called Null hypothesis. Null hypothesis states that there is no significant difference betwee the two samples e.g. there is no difference between the e... | 3 | The probability of finding a significant difference is 1% | The probability of declaring a significant difference, when there is truly no difference, is 1% | The difference is not significant 1% times and significant 99% times | The power of the test used is 99% | Social & Preventive Medicine | null | 1fbdb2ab-d126-4c1a-bd75-92825ac487b4 | single |
The most preferred incision in case of implant surgery is: | null | 2 | Oblique incision | Crestal incision | Crevicular incision | Beveled incision | Dental | null | 02634bad-5cc6-4fb8-bb07-6c6c424d7863 | single |
In designing the occlusal rest seat, the floor of the rest
seat should be inclined towards the | null | 2 | Buccal surface | Centre of the tooth | Lingual surface | Marginal ridge | Dental | null | e0eb5c20-ab0a-4f22-9ed8-eed63935495e | single |
Which of the following carcinoma most frequently metastasizes to brain? | . Small cell carcinoma lung | 1 | Small cell carcinoma lung | Prostate cancer | Rectal carcinoma | Endometrial cancer | Pathology | null | 4d0dbab7-f2ba-474f-a0f4-a7f214c0bbfe | multi |
Fracture of 1st metacarpal bone: (Repeat) | Ans: B (Bennett's fracture) Ref: Apley's Orthopedics, 9th ed. & Internet SourcesExplanation:FractureDescriptionAviator fractureFracture of neck of TalusBankart's fractureFracture of anterior glenoid associated with anterior shoulder dislocationBarton's fractureDistal radius fracture involving the articular surface with... | 2 | B arton' s fractu re | Bennett's fracture | Chauffer's fracture | Boxer's fracture | Orthopaedics | Bennett's Fracture-Dislocation | abd1e724-65f1-4649-bcf6-8992b1d41f4e | single |
Which one of the following microbe, found in ear discharge, has a high predilection for meningitis | Ans. (d) Streptococcus pneumoniae Ref: Dhingra 5th/61, 81 * Meningitis is the commonest intracranial complication of otitis media. * In infants and children, otogenic meningitis usually follows acute otitis media while in adults, it is due to chronic middle ear infection. * Most common organisms in infants and children... | 4 | H. influenza | Moraxella species | Staphylococcus aureus | Streptococcus pneumoniae | Microbiology | Streptococci | d77139cc-e6bb-4aff-accb-5ea6cf5b889f | single |
Adipocure occurs in | Warm, moist climate essential.
Clostridium - lecithinase.
Intrinsic lipase. | 2 | Arsenic poison | Lying in water | Body inside car locked doors | Inside shallow soil | Forensic Medicine | null | 4dde818d-c8b0-4c19-be68-ae9ff3e83d35 | multi |
Blount's disease is associated with all of the following, EXCEPT: | Blount's disease is characterized by varus and internal tibial torsion and genu recurvatum, with varus of the proximal tibia being the primary deformity. It is not associated with external tibial torsion. Ref: Operative techniques in pediatric ohopedics, by John M.Flynn, Sam W.Wiesel, Page 205, 206. | 4 | Genu varum | Genu Recurvatum | Internal Tibial Torsion | External Tibial Torsion | Surgery | null | 3245c9f4-65a1-4531-8ee9-c39718df7ecf | multi |
Which of the following concentrations of epinephrine does not correspond to the respective route of administration | Adrenaline is the drug of choice(0.3 - 0.5 ml of 1:1000 solution) for angioneurotic oedema IM is the preferred route. Adrenaline is given with local anaesthetic also. 1:10000-1:20000 IV adrenaline is used. 1:1000 is for subcutaneous route and Intramuscular route. For inhalation route, conc. is 1:100 From H.L. Sharma 3r... | 2 | 1:10000 for intravenous route | 1: 1000 for inhalational route | 1: 1000 for intramuscular route | 1: 1000 for subcutaneous route | Pharmacology | Autonomic nervous system | b5356efc-94b3-422b-a875-271da977decc | single |
Fern test is due to: | Ans. is b, i.e. Presence of NaCl under estrogenic effectRef: Shaw 15th/ed, p215* Fern test is for documenting ovulation.* Procedure: A specimen of cervical mucus is obtained and is spread on a clean glass slide and allowed to dry. It is then viewed under the low power microscope.* Result and interpretation: Under the i... | 2 | Presence of NaCl under progesterone effect | Presence of NaCl under estrogenic effect | LH/FSH | Mucus secretion by Glands | Gynaecology & Obstetrics | Endometriosis and Infertility | fdf9fe84-870f-4c71-abba-f62c6eb0516d | single |
Safety pin appearance is shown by? | Hemophilus ducreyi is a sho ovoid bacillus with a tendency to occur in the end to end pairs or sho chains. It is Gram-negative but may often appear Gram-positive and frequently shows Bipolar staining. The bacilli may be arranged in small groups or whole or in parallel chains giving a School of Fish or Railroad track ap... | 1 | Hemophilus ducreyi | Chlamydia | Donovani granulomatis | Mycoplasma | Microbiology | general microbiology | 64adc2c1-155f-427a-af84-f6b544f378b8 | single |
Not a contraindication for combined spinal and epidural anaesthesia: | (Refer: Morgan’s, Clinical Anaesthesia, 4th edition, pg no: 290-295, 396-398)
Contraindications of neuraxial (Spinal/Epidural) blockade | 4 | Platelet count> 50,000 | Patient on clopidogrel | Local infection | Patient on antihypertensive medication | Unknown | null | b11d246b-219a-44bb-bb7e-53fb4502d89a | single |
Acute myocardial infarct scintigraphy is done with – | Perfusion Scan → Thallium (mc), technetium, MIBI.
Infarct Scan → Technetium pyrophosphate. | 4 | Thallium | Gallium | Neodynium | Tc stannous pyrophosphate | Radiology | null | 7bb578b6-e748-4b56-9cea-968239892d92 | multi |
Drugs that have been found to be useful in compensated heart failure include all of the following except: | These agents are indicated for the treatment of acute decompensated CHF. Digitalis (Na+ - K+ ATPase inhibitor) is indicated both for acute treatment as well as maintenance in CHF as digoxin is the only orally effective inotropic drug available.
β2 (beta2) adrenergic receptor agonists, also known as adrenergic β2 recept... | 3 | Na+ K+ ATPase inhibitors | Alpha blockers | Beta receptor agonists | Beta receptor antagonists | Pharmacology | null | 928ad91f-75df-4c6b-8b96-ae8d468a0f72 | multi |
All the following are sulphur containing amino acids found in proteins except | Sulfur-containing amino acids: Cysteine, Methionine.
Reference: Vasudevan 7th ed, pg 24 | 4 | Cysteine | Cystine | Methionine | Threonine | Biochemistry | null | ccd1bf99-45f1-449b-bb85-bf5d025f7e48 | multi |
Maturation index in mid-secretory phase of menstrual cycle is | Basics: Estrogen Promotes, Progesterone inhibits Squamous cell maturation The lateral vaginal wall cells can be sampled by scraping them with a spatula and then plating them on a slide. Sample often obtained simultaneous with Pap smear. (Students should not confuse that squamous cells sampled from the lateral vaginal w... | 3 | 0/95/5 | 80/20/0 | 0/70/30 | 0/40/60 | Gynaecology & Obstetrics | Normal Menstruation, Abnormal Menstruation, Menopausal Physiology and forsight of conception | bb6be01a-8b2c-49cc-81b3-c2cf1b03f72c | single |
Absolute contraindication to intra-uterine device is: | Absolute contraindications to intra uterine devices are: History of ectopic pregnancy Suspected pregnancy Pelvic inflammatory disease Vaginal bleeding of unknown etiology Cancer of cervix, uterus, adnexa and other pelvic tumours Ref: Park, 22nd edition pg: 449;Park 21st Ed Page 460. | 2 | Anaemia | History of ectopic pregnancy | History of pelvic inflammatory disease | None of the above | Social & Preventive Medicine | null | 89757587-7fcc-4226-999b-8436333f0830 | multi |
True about protease inhibitors are all EXCEPT: | Retroviral protease Inhibitors (Pis) An aspaic protease enzyme encoded by HIV is involved in the production of structural proteins and enzymes (including reverse transcriptase) of the virus. The large viral polyprotein is broken into various functional components by this enzyme. This protease acts at a late step in HIV... | 4 | Acts as a substrate for P-glycoprotein (P-gp) and action is mediated by mdr-1 gene | Undergo hepatic oxidative metabolism | Protease inhibitors interfere with metabolism of several drugs | Saquinavir causes maximum induction of CYP3A4 | Pharmacology | Chemotherapy | 4cbafa0d-eed5-4f1b-aad0-01efecb24fd6 | multi |
All of the following statements about Ranolazine are true, except: | Ans. D. Hypotension is an established adverse effectUnlike other anti-anginal agents, Ranolazine does not decrease heart rate / blood pressure. It does not cause hypotension. | 4 | Piperazine derived antianginal agent | May be used as first line agent in chronic angina | May improve Glycemic control | Hypotension is an established adverse effect | Pharmacology | Anti-Anginal | 02c6e860-e12e-46dc-9ec7-384d6c555dc4 | multi |
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