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Sodium ethoxide-Safety-Sodium ethoxide is a strong base, and is therefore corrosive.
milkshake721/2.1M-wiki-STEM
Speed garage-Speed garage-Speed garage (occasionally known as plus-8) is a genre of electronic dance music, associated with the UK garage scene, of which it is regarded as one of its subgenres.
milkshake721/2.1M-wiki-STEM
Speed garage-Characteristics-Speed garage features sped-up NY garage 4-to-the-floor rhythms that are combined with breakbeats. Snares are placed as over the 2nd and the 4th kickdrums, so in other places of the drum pattern. Speed garage tunes have warped, heavy basslines, influenced by jungle and reggae. Sweeping bass ...
milkshake721/2.1M-wiki-STEM
Speed garage-Characteristics-A widely regarded pioneer of the speed garage sound is record producer, DJ and remixer Armand van Helden, whose Dark Garage remix of the Sneaker Pimps' "Spin Spin Sugar" in 1996 helped bring the style of speed garage into the mainstream arena.
milkshake721/2.1M-wiki-STEM
Speed garage-Notable songs/remixes-The following is a list of notable songs and official remixes which not only charted but were popular within the speed garage scene: "Sugar Is Sweeter (Armand's Drum 'n' Bass Mix)" (1996) / "Spin Spin Sugar (Armand's Dark Garage Mix)" (1997) / "Digital (Armand Van Helden's Speed Garag...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Surface plasmon resonance microscopy-Surface plasmon resonance microscopy (SPRM), also called surface plasmon resonance imaging (SPRI), is a label free analytical tool that combines the surface plasmon resonance of metallic surfaces with imaging of the metallic surface.
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Surface plasmon resonance microscopy-The heterogeneity of the refractive index of the metallic surface imparts high contrast images, caused by the shift in the resonance angle. SPRM can achieve a sub-nanometer thickness sensitivity and lateral resolution achieves values of micromete...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-History-The concept of classical SPR has been since 1968 but the SPR imaging technique was introduced in 1988 by Rothenhäusler and Knoll. Capturing a high resolution image of low contrast samples for optical measuring techniques is a near impossible task until the introduction of SP...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-Surface plasmons or surface plasmon polaritons are generated by coupling of electrical field with free electrons in a metal. SPR waves propagate along the interface between dielectrics and a conducting layer rich in free electrons.As shown in Figure 2, when light passes f...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-In the TIR process some portion of the reflected light leaks a small portion of electrical field intensity into medium 2 (η1 > η2). The light leaked into the medium 2 penetrates as an evanescent wave. The intensity and penetration depth of the evanescent wave can be calcu...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-Radiation of different wavelengths (green, red and blue) was converted into surface plasmon polaritons, through the interaction of the photons at the metal/dielectric interface. Two different metal surfaces were used; gold and silver. The propagation length of the SPP alo...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-where δSPP is the propagation length; ε’m and ε’’m are the relative permittivity of the metal and λ0 is the free space wavelength.The metallic film is capable of absorbing light due to the coherent oscillation of the conduction band electrons induced by the interaction wi...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-Nanorods exhibit two absorption peaks in the UV-vis region due to longitudinal and transversal oscillation, for gold nanorods the transverse oscillation generates a peak at 520 nm, while the longitudinal oscillation generates absorption at longer wavelengths, within a ran...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-The absorption intensity and wavelength of gold and silver depends on the size and shape of the particles.In Figure 5, the size and shape of silver nanoparticles influenced the intensity of the scattered light and maximum wavelength of silver nanoparticles. The triangular...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-Plasmon excitation methods Surface plasmon polaritons are quasiparticles, composed by electromagnetic waves-coupled to free electrons of the conduction band of metals. One of widely used methods uses to couple p-polarized light with the metal-dielectric interface is prism...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-Prism couplers are the most widely used to excite surface plasmon polaritons. This method is also called Kretschmann–Raether configuration, where TIR creates an evanescent wave that couples the free electrons of the metal surface. High numerical aperture objective lenses...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-Prism coupling Kretschmann–Raether configuration is used to achieve resonance between light and free electrons of the metal surface. In this configuration a prism with high refractive index is interfaced with a metal film. Light from a source propagates through the prism ...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-The evanescent wave penetrates a characteristic distance into the less optically dense medium where it is attenuated.Figure 6 shows the Kretschmann–Raether configuration, where a prism with refractive index of η1 is coupled to a dielectric surface with a refractive index ...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-Waveguide coupling The electromagnetic waves are conducted through an optical waveguide. When light enters to the region with a thin metal layer, it evanescently penetrates through the metal layer exciting a Surface Plasmon Wave (SPW). In waveguide coupling configuration,...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-In Figure 8, electromagnetic waves are guided through a wave-guiding layer, once the optical waves reached the interface wave-guiding layer metal an evanescent wave is created. The evanescent wave excites the surface plasmon at the metal-dielectric interface. Grating coup...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-where θ is the angle of incidence, ksp is the propagation constant of the surface plasmon, and n(p) is the refractive index of the prism. When the wave vector of the SPW, ksp matches the wave vector of the incident light k x {\textstyle k_{x}} , SPW is expressed as: Here...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-The propagation of the surface plasmons is intensely affected by a thin film coating on the conducting layer. The resonance angle θ shifts, when the metal surface is coated with a dielectric material, due to the change of the propagation vector k of the surface plasmon. T...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-It measures the reflectance percentage (%R) from a prism/metal film assembly as a function of the incident angle at a fixed excitation wavelength. When the angle of incidence matches the propagation constant of the interface, this mode is excited at expenditure of the ref...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-The resonance angle can be found by using Equation 11.
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-where n1 is n2 and ng are the refractive index of medium 1, 2 and the metal layer, respectively.Using TIR two-dimensional imaging is possible to achieve spatial differences in %R at a fixed angle θ. A beam of monochromatic light is used to irradiate the sample at a fixed ...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-The minimum value of %R at the resonance angle provides SPRM.Huang and collaborators developed a microscope with an objective with high numerical aperture (NA), which improve the lateral resolution at expense of the longitudinal resolution.
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-Lateral resolution The resolution of a conventional light microscopy is limited by the light diffraction limit. In SPRM, the excited surface plasmons adopt a horizontal configuration from the incident beam light. The polaritons will travel along the metal-dielectric inter...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Principles-The separation between two areas should be approximately the magnitude of ksp in order to be resolved. Berger, Kooyman and Greve showed that the lateral resolution can be tuned by changing the excitation wavelength, the better resolution is achieved when the excitation en...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Instrumentation-The surface plasmon resonance microscopy is based on surface plasmon resonance and recording desired images of the structures present on the substrate using an instrument equipped with a CCD camera. In the past decade, SPR sensing has been demonstrated to be an excee...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Sample preparation-To perform measurements for SPRM, the sample preparation is a critical step. There are two factors that can be affected by the immobilization step: one is the reliability and reproducibility of the acquire data. It is important to ensure stability to the recogniti...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-SPRM is a useful technique for measuring concentration of biomolecules in the solution, detection of binding molecules and real time monitoring of molecular interactions. It can be used as biosensor for surface interactions of biological molecules: antigen-antibody bind...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-SPRM is also advantageous to detect the site-specific attachment of lymphocyte B or T on antibody array. This technique is convenient to study the label free and real time interactions of cells on the surface. So SPRM can be served as diagnostic tool for cell surface ad...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-In order to understand the structural details of membrane proteins, there is a need of alternate analytical tool, which can provide three-dimensional and sequential resolutions that can monitor membrane proteins. Atomic force microscopy (AFM) is an excellent method for ...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-Furthermore, host protein may be affected by the labeling.Binding kinetics of MP's in the single living cells can be studied via label free imaging method based on SPR Microscopy without extracting the proteins from the cell membranes, which help scientists to work with...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-Detection of DNA hybridization SPR imaging is used to study the multiple adsorption interactions in an array format under same experimental conditions. Nelson and his coworkers introduced a multistep procedure to create DNA arrays on gold surfaces for use with SPR imagi...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-DNA array is fabricated to test the G–G mismatch stabilizing properties of the naphthyridine dimer. Each of the four immobilized sequences in the array differed by one base. The position of this base is indicated by an X in sequence 1 as shown in Figure 16. The SPR diff...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-Antibody binding to protein arrays SPR imaging can be used to study the binding of antibodies to protein array. Amine functionalities on the gold surface with proteins array, is used to study binding of antibodies. Immobilization of the protein was done by flowing prote...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-Coupled with mass spectrometry Discovery and validation of protein biomarkers are crucial for diseases diagnosis. Coupling of SPRM with MALDI-mass spectrometer (SUPRA-MS) enables the multiplex quantification of binding and molecular characterization on the basis of diff...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-where ∂n∂c is the index increment of the molecule and SPR is the sensitivity prism, reflectivity.
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-Clean mass spectrum was obtained for LAG3 protein due to good tryptic digestion and homogeneity of the matrix (α-cyano-4-hydroxycinnamic acid). Relatively high intensity m/z peak of LAG3 protein was found at 1,422.70amu with average mascot score of 87.9 ± 2.4. Validatio...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-DNA aptamers Aptamers are particular DNA ligands that target biomolecules such as proteins. SPR imaging platform would be a good choice to characterize aptamer -protein interactions. To study the aptamer-protein interaction, first oligonucleotides are grafted through fo...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-[THR---APT] = cTHR – [THR], the equilibrium concentration of thrombin attached to aptamers in solution and [APT] = cAPT – [THR---APT], the concentration of free aptamers in solution.
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-Surface phase dissociation constant KDsurf (3.84 ± 0.68) is obtained by fitting Langmuir adsorption isotherm on equilibrium signals. Both dissociation constants are significantly different because KDsurf is dependent on the surface grafting density as shown in Figure 19...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-Detection of polymer interaction Despite of using surface plasmon resonance imaging (SPRi) in biology to characterize interactions between two biological molecules, it is also useful to monitor the interactions between two polymers. In this approach, one polymer, called...
milkshake721/2.1M-wiki-STEM
Surface plasmon resonance microscopy-Applications-Bio-mineralization One of the important class of biomaterials is polymer hydroxyapatite that is remarkably useful in the field of bone regeneration because of its resemblance with natural bone material. The advantage of hydroxyapatite, (Ca10(PO4)6(OH)2, is being started...
milkshake721/2.1M-wiki-STEM
Form grabbing-Form grabbing-Form grabbing is a form of malware that works by retrieving authorization and log-in credentials from a web data form before it is passed over the Internet to a secure server. This allows the malware to avoid HTTPS encryption. This method is more effective than keylogger software because it ...
milkshake721/2.1M-wiki-STEM
Form grabbing-History-The method was invented in 2003 by the developer of a variant of a trojan horse called Downloader.Barbew, which attempts to download Backdoor.Barbew from the Internet and bring it over to the local system for execution. However, it was not popularized as a well known type of malware attack until t...
milkshake721/2.1M-wiki-STEM
Form grabbing-Known occurrences-A trojan known as Tinba (Tiny Banker Trojan) has been built with form grabbing and is able to steal online banking credentials and was first discovered in 2012. Another program called Weyland-Yutani BOT was the first software designed to attack the macOS platform and can work on Firefox....
milkshake721/2.1M-wiki-STEM
Form grabbing-Known occurrences-The British Airways mobile application also loads a webpage built with the same CSS and JavaScript components as the main website, including the malicious script installed by Magecart. Thus, the payments made using the British Airways mobile app were also affected.
milkshake721/2.1M-wiki-STEM
Form grabbing-Countermeasures-Due to the recent increase in keylogging and form grabbing, antivirus companies are adding additional protection to counter the efforts of key-loggers and prevent collecting passwords. These efforts have taken different forms varying from antivirus companies, such as safepay, password mana...
milkshake721/2.1M-wiki-STEM
Conductive deafness-ptosis-skeletal anomalies syndrome-Conductive deafness-ptosis-skeletal anomalies syndrome-Conductive deafness-ptosis-skeletal anomalies syndrome, also known as Jackson Barr syndrome is a rare presumably autosomal recessive genetic disorder characterized by conductive hearing loss associated with ext...
milkshake721/2.1M-wiki-STEM
Pudendal canal-Pudendal canal-The pudendal canal (also called Alcock's canal) is an anatomical structure formed by the obturator fascia (fascia of the obturator internus muscle) lining the lateral wall of the ischioanal fossa. The internal pudendal artery and veins, and pudendal nerve pass through the pudendal canal, a...
milkshake721/2.1M-wiki-STEM
Pudendal canal-Clinical significance-Pudendal nerve entrapment can occur when the pudendal nerve is compressed while it passes through the pudendal canal.
milkshake721/2.1M-wiki-STEM
Pudendal canal-History-The pudendal canal is also known as Alcock's canal, named after Benjamin Alcock.
milkshake721/2.1M-wiki-STEM
Atlanto-occipital joint-Atlanto-occipital joint-The atlanto-occipital joint (Capsula articularis atlantooccipitalis) is an articulation between the atlas bone and the occipital bone. It consists of a pair of condyloid joints. It is a synovial joint.
milkshake721/2.1M-wiki-STEM
Atlanto-occipital joint-Structure-The atlanto-occipital joint is an articulation between the atlas bone and the occipital bone. It consists of a pair of condyloid joints. It is a synovial joint. Ligaments The ligaments connecting the bones are: Two articular capsules Posterior atlanto-occipital membrane Anterior atlant...
milkshake721/2.1M-wiki-STEM
Atlanto-occipital joint-Function-The movements permitted in this joint are: (a) flexion and extension around the mediolateral axis, which give rise to the ordinary forward and backward nodding of the head. (b) slight lateral motion, lateroflexion, to one or other side around the anteroposterior axis.Flexion is produced...
milkshake721/2.1M-wiki-STEM
Atlanto-occipital joint-Clinical significance-Dislocation The atlanto-occipital joint may be dislocated, especially from violent accidents such as traffic collisions. This may be diagnosed using CT scans or magnetic resonance imaging of the head and neck. Surgery may be used to fix the joint and any associated bone fra...
milkshake721/2.1M-wiki-STEM
Nestopia-Nestopia-Nestopia UE - and its predecessor Nestopia - are an open-source NES/Famicom emulator designed to emulate the NES hardware as accurately as possible.
milkshake721/2.1M-wiki-STEM
Nestopia-Features-The requirements for the original Nestopia were considered higher than some of its contemporaries such as Stella. In order to run an optimal emulation, the program requires a minimum 800 MHz processor. Its high requirement is due to its accurate emulation of the NES hardware. The emulator will play mo...
milkshake721/2.1M-wiki-STEM
Nestopia-Development history-Nestopia was originally developed for Windows by Martin Freij. Richard Bannister and R. Belmont later ported it to Mac OS X and Linux, respectively. Original development ended in 2008, but forked into Nestopia UE.
milkshake721/2.1M-wiki-STEM
Solar eclipse of November 15, 2096-Solar eclipse of November 15, 2096-An annular solar eclipse will occur on Wednesday, November 14 and Thursday, November 15, 2096. A solar eclipse occurs when the Moon passes between Earth and the Sun, thereby totally or partly obscuring the image of the Sun for a viewer on Earth. An a...
milkshake721/2.1M-wiki-STEM
Solar eclipse of November 15, 2096-Related eclipses-Solar eclipses 2094–2098 This eclipse is a member of a semester series. An eclipse in a semester series of solar eclipses repeats approximately every 177 days and 4 hours (a semester) at alternating nodes of the Moon's orbit.
milkshake721/2.1M-wiki-STEM
Solar eclipse of November 15, 2096-Related eclipses-Saros 144 It is a part of Saros cycle 144, repeating every 18 years, 11 days, containing 70 events. The series started with partial solar eclipse on April 11, 1736. It contains annular eclipses from July 7, 1880 through August 27, 2565. There are no total eclipses in ...
milkshake721/2.1M-wiki-STEM
Assisted-opening knife-Assisted-opening knife-An assisted-opening knife is a type of folding knife which uses an internal mechanism to finish the opening of the blade once the user has partially opened it using a flipper or thumbstud attached to the blade.When the knife is in the closed position, the blade is held in p...
milkshake721/2.1M-wiki-STEM
Assisted-opening knife-Legality-United States Although commonly confused with switchblade knives, a switchblade can be opened automatically simply with the push of a button, but the user of an assisted-opening knife must open it about one-quarter of the way (45°) before the mechanism opens the knife the rest of the way...
milkshake721/2.1M-wiki-STEM
Assisted-opening knife-Legality-United Kingdom In 2019, the Offensive Weapons Act prohibiting automatic flick knives was amended to prohibit: “(a)any knife which has a blade which opens automatically—(i)from the closed position to the fully opened position, or (ii)from a partially opened position to the fully opened po...
milkshake721/2.1M-wiki-STEM
Assisted-opening knife-Trade names-Trade names for assisted-opening knives are: Forward Action Spring Technology, A/O Knife, Torsion Assist Knife, Assisted Knife, Spring Assist Knife, Spring Assisted Knife, Quick Release, Quick Draw, Alternative Automatic, Outburst, SpeedSafe, Blade Launcher, S.A.T (SOG Assisted Techno...
milkshake721/2.1M-wiki-STEM
Assisted-opening knife-History-The first assisted opening knife was designed by Blackie Collins in 1995 and was named the "Strut-and-Cut"; it was based on the strut of his Ducati motorcycle. A similar concept was developed three years later by knifemaker Ken Onion with Onion's idea based on a similar mechanism in his H...
milkshake721/2.1M-wiki-STEM
My Friend the Monkey-My Friend the Monkey-My Friend the Monkey is a 1939 Fleischer Studios animated short film starring Betty Boop.
milkshake721/2.1M-wiki-STEM
My Friend the Monkey-Synopsis-A hurdy-gurdy man comes by Betty Boop's house. She wants to buy his cute baby monkey. While Betty is outside haggling over the price, the monkey is inside causing plenty of trouble for Pudgy the Pup.
milkshake721/2.1M-wiki-STEM
Sony timer-Sony timer-The Sony timer (ソニータイマー, Sonī taimā), or Sony kill switch, is an urban legend that electronic devices produced by Sony are equipped with a timer which, upon reaching a deliberately preset deadline, causes the product to stop functioning, forcing the user to buy a replacement. The legend began in J...
milkshake721/2.1M-wiki-STEM
Sony timer-History-In Japan, Sony timer's legend spread around in the late 1980s and early 1990s and, although there has never been any conclusive evidence that would confirm this myth, many Japanese people believe it, and it's used as a joke in comics and posted on online message boards. The legend remained confined t...
milkshake721/2.1M-wiki-STEM
Sony timer-History-However, the Sony timer legend had already spread widely across the World Wide Web, becoming part of the Internet culture itself.The legend resurfaced again in 2021 when it was discovered that an anti-cheat measure in PlayStation Network had the potential to render games unplayable on the PlayStation...
milkshake721/2.1M-wiki-STEM
Infrapatellar fat pad syndrome-Infrapatellar fat pad syndrome-Infrapatellar fat pad syndrome, also known as Hoffa's disease, is when pain in the front of the knee occurs due to problems with the infrapatellar fat pad. Pain is generally just below the kneecap. Symptoms may worsen if the knee is overly straightened or be...
milkshake721/2.1M-wiki-STEM
Infrapatellar fat pad syndrome-Treatment-Treatment is generally by steroid injections and physical therapy. If this is not effective surgery removal may be tried. High quality evidence for surgery is lacking as of 2015.
milkshake721/2.1M-wiki-STEM
LMO3-LMO3-LIM domain only protein 3 is a transcription co-factor, which in humans is encoded by the LMO3 gene. LMO3 interacts with the tumor suppressor p53 and regulates its function. LMO3 is considered to be an oncogene in Neuroblastoma.
milkshake721/2.1M-wiki-STEM
Secondary suite-Secondary suite-Secondary suites (also known as accessory dwelling units, ADUs, in-law apartments, granny flats, and garden suites) are self-contained apartments, cottages, or small residential units, that are located on a property that has a separate main, single-family home, duplex, or other residenti...
milkshake721/2.1M-wiki-STEM
Secondary suite-Description-Background Naming conventions vary by time-period and location but secondary suites can also be referred to as an accessory dwelling unit (ADU), mother-in-law suite, granny flat, coach house, laneway house, Ohana dwelling unit, granny annexe, granny suite, in-law suite, and accessory apartme...
milkshake721/2.1M-wiki-STEM
Secondary suite-Description-Relationship to main residence A secondary suite is considered "secondary" or "accessory" to the primary residence on the parcel. It normally has its own entrance, kitchen, bathroom and living area. There are three types of accessory units: interior, interior with modification, and detached....
milkshake721/2.1M-wiki-STEM
Secondary suite-Description-A suite attached to a single-detached dwelling at grade (similar to a "duplex" but that word implies two distinct legal parcel of land with houses that simply share a wall) A suite detached from the principal dwelling (a "garden suite" or "guesthouse", called a "laneway house" if it faces th...
milkshake721/2.1M-wiki-STEM
Secondary suite-Benefits and drawbacks-Communities that support secondary suites may do so to support a diverse set of goals. Commonly cited benefits of secondary suites include the following;. Benefits Creating more affordable housing options as secondary suites are typically small, easy to construct, increase housing...
milkshake721/2.1M-wiki-STEM
Secondary suite-Benefits and drawbacks-Supporting diverse and multi-generational households as seniors, young-adults, or other relatives can live on the same property as their families but still maintain some independence and privacy. For seniors, this kind of arrangement can improve their social life, allow family mem...
milkshake721/2.1M-wiki-STEM
Secondary suite-Benefits and drawbacks-Improve home maintenance and homeownership rates by providing a reliable rental income that can support mortgage payments or home maintenance. Creating energy-efficient housing as the small and often attached units require fewer resources. ADUs can be integrated into the scale and...
milkshake721/2.1M-wiki-STEM
Secondary suite-Benefits and drawbacks-Drawbacks Properties which are linked in complex ways may cause difficulties should one of the units be sold or rented out to a third party. Should this occur, each party requires permission from the other party to make certain types of changes to the building. When one unit is so...
milkshake721/2.1M-wiki-STEM
Secondary suite-By country-Australia In Australia, the term 'granny flat' is often used for a secondary dwelling on a property. The land is not subdivided with construction requiring approval from the council or relevant authority. The approval processes vary between States and Territories, and between councils. This i...
milkshake721/2.1M-wiki-STEM
Secondary suite-By country-Canada Secondary suites have existed in Canada since the 19th century where they took the form of coach houses, servant houses, stables converted to permanent apartments, and small apartments for young people within large houses. Secondary suites became increasing popular during the economic ...
milkshake721/2.1M-wiki-STEM
Secondary suite-By country-CMHC (government program) The Canada Mortgage and Housing Corporation provides a financial assistance program to help Canadians create affordable housing for low-income seniors and adults with a disability within a secondary suite. The program is called the Residential Rehabilitation Assistan...
milkshake721/2.1M-wiki-STEM
Secondary suite-By country-British Columbia After adopting legislation in 2009 to support secondary suites, Vancouver, British Columbia has become a leading city of their construction in North America. In the city, approximately a third of single-family houses have legally permitted secondary suites, many of which are ...
milkshake721/2.1M-wiki-STEM
Secondary suite-By country-Europe In German speaking countries a secondary suite is known as an Einliegerwohnung. In Norway, particularly in the bigger cities, it is quite common to build separate adjoined smaller flats for renting out. The owner of the main flat will rent out the smaller adjoined flats. In the United ...
milkshake721/2.1M-wiki-STEM
Secondary suite-By country-United States In the United States, secondary suites are generally referred to as accessory dwelling units or "ADUs". Zoning permissions and laws concerning accessory dwelling units can vary widely by state and municipality. Accessory dwelling units were popular in the early 20th century in t...
milkshake721/2.1M-wiki-STEM
Secondary suite-By country-Several states have enacted legislation to promote accessory dwelling units. In California, Government Code Sections 65852.150, 65852.2 & 65852.22 pertain to local regulation of ADUs. SB 1069 and AB 2299 are California bills approved in 2016 and effective January 1, 2017, that limit local gov...
milkshake721/2.1M-wiki-STEM
Secondary suite-By country-The states of Vermont and New Hampshire have also adopted a number of bills that promote accessory dwelling units and reduce regulatory barriers to ADU construction. The State of Illinois considered, but did not adopt, HB 4869 which would have required municipalities to permit (and reasonably...
milkshake721/2.1M-wiki-STEM
Secondary suite-By country-Several local governments across the United States have enacted ordinances to both permit and promote accessory dwelling units. Some cities have included accessory dwelling units in larger missing middle housing and affordable housing strategies including Seattle, Portland, and Minneapolis. M...
milkshake721/2.1M-wiki-STEM
Micromixing-Micromixing-In pharmaceutics, micromixing is a process in which ingredient particles rearrange to form a blend. Development of pharmaceutical formulations requires understanding how the ingredients blend with each other and how the blending progresses through different stages. It is also important to establ...
milkshake721/2.1M-wiki-STEM
Micromixing-Optimal blending-In order to achieve optimal blending, the micromixing process must be studied to determine mixing parameters such as blending time, blending speed, type and size of blender. When blending is performed too long, overblending may occur, with particles re-aggregating, resulting in segregation ...
milkshake721/2.1M-wiki-STEM
Micromixing-Tools-Formulation scientists and technologists need tools to select ingredients for new formulations. Tablets contain multiple ingredients beyond the active pharmaceutical ingredients (API) such as fillers, tableting agents, disintegrants, and absorption enhancers or agents that slow down and control absorp...
milkshake721/2.1M-wiki-STEM
Micromixing-Methods-In order to study the rate and uniformity of blending, destructive analytical methods, such as dissolution followed by chromatographic separation and detection are often used. These methods require samples to be pulled from the blend, followed by time-consuming laboratory analysis. In production, su...
milkshake721/2.1M-wiki-STEM
Micromixing-Hyperspectral imaging-Near-infrared hyperspectral imaging can show the distribution of ingredients in pharmaceutical tablets. In addition to laboratory analysis, imaging of near line pull-samples has been used to indicate whether the mixing endpoint has been achieved. However, such measurements were perform...
milkshake721/2.1M-wiki-STEM
Statite-Statite-A statite (from the words static and satellite) is a hypothetical type of artificial satellite that employs a solar sail to continuously modify its orbit in ways that gravity alone would not allow. Typically, a statite would use the solar sail to "hover" in a location that would not otherwise be availab...
milkshake721/2.1M-wiki-STEM