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DEC Alpha-Alpha-based systems-Digital also produced single-board computers based on the VMEbus for embedded and industrial use. The first generation includes the 21068-based AXPvme 64 and AXPvme 64LC, and the 21066-based AXPvme 160. These were introduced on March 1, 1994. Later models such as the AXPvme 100, AXPvme 166... | milkshake721/2.1M-wiki-STEM |
DEC Alpha-Alpha-based systems-The 21066 chip is used in the DEC Multia VX40/41/42 compact workstation and the ALPHAbook 1 laptop from Tadpole Technology.
In 1994, DEC launched a new range of AlphaStation and AlphaServer systems. These use 21064 or 21164 processors and introduced the PCI bus, VGA-compatible frame buffer... | milkshake721/2.1M-wiki-STEM |
DEC Alpha-Alpha-based systems-A number of OEM motherboards were produced by DEC, such as the 21066 and 21068-based AXPpci 33 "NoName", which was part of a major push into the OEM market by the company, the 21164-based AlphaPC 164 and AlphaPC 164LX, the 21164PC-based AlphaPC 164SX and AlphaPC 164RX and the 21264-based A... | milkshake721/2.1M-wiki-STEM |
DEC Alpha-Alpha-based systems-To assist third parties in developing hardware and software for the platform, DEC produced Evaluation Boards, such as the EB64+ and EB164 for the Alpha 21064A and 21164 microprocessors respectively.
The 21164 and 21264 processors were used by NetApp in various network-attached storage syst... | milkshake721/2.1M-wiki-STEM |
Milk equivalent-Milk equivalent-Milk equivalent is a measure of the quantity of fluid milk used in a processed dairy product. Measured on a milkfat basis, it takes about 21.8 pounds of farm milk to make a pound of butter, and about 9.2 pounds to make a pound of American cheese. Measured on a skim solids basis, it takes... | milkshake721/2.1M-wiki-STEM |
SimRefinery-SimRefinery-SimRefinery is a computer management simulation game designed to simulate Chevron's Richmond refinery operation. It was developed by the Maxis Business Simulations division of Maxis in 1993. John Hiles, who was the head of the Maxis division, was a lead designer on the project. | milkshake721/2.1M-wiki-STEM |
SimRefinery-Development-After the success of SimCity, Maxis received numerous requests from various companies to develop simulations for their industries. After rejecting many requests from other companies, the team eventually agreed to make a prototype of SimRefinery for Chevron: [SimRefinery was] a simulation of thei... | milkshake721/2.1M-wiki-STEM |
SimRefinery-Release and rediscovery-As a commissioned business aid, it was not made available to the public. Until 2020, little information about the game had existed, though Maxis had discussed its creation and some screenshots existed. Most of the assets stayed with Maxis Business Simulations, which Maxis eventually ... | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-Anti-neutrophil cytoplasmic antibody-Anti-neutrophil cytoplasmic antibodies (ANCAs) are a group of autoantibodies, mainly of the IgG type, against antigens in the cytoplasm of neutrophils (the most common type of white blood cell) and monocytes. They are detected as a blood test in ... | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-ANCA IF patterns-Immunofluorescence (IF) on ethanol-fixed neutrophils is used to detect ANCA, although formalin-fixed neutrophils may be used to help differentiate ANCA patterns. ANCA can be divided into four patterns when visualised by IF; cytoplasmic ANCA (c-ANCA), C-ANCA (atypica... | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-ANCA antigens-The c-ANCA antigen is specifically proteinase 3 (PR3). p-ANCA antigens include myeloperoxidase (MPO) and bacterial permeability increasing factor Bactericidal/permeability-increasing protein (BPI). Other antigens exist for c-ANCA (atypical), however many are as yet unk... | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-ELISA-Enzyme-linked immunosorbent assay (ELISA) is used in diagnostic laboratories to detect ANCAs. Although IF can be used to screen for many ANCAs, ELISA is used to detect antibodies to individual antigens. The most common antigens used on an ELISA microtitre plate are MPO and PR3... | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-Development-It is poorly understood how ANCA are developed, although several hypotheses have been suggested. There is probably a genetic contribution, particularly in genes controlling the level of immune response – although genetic susceptibility is likely to be linked to an enviro... | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-Development-Theory of molecular mimicry Microbial superantigens are molecules expressed by bacteria and other microorganisms that have the power to stimulate a strong immune response by activation of T-cells. These molecules generally have regions that resemble self-antigens that pr... | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-Development-Theory of defective apoptosis Neutrophil apoptosis, or programmed cell death, is vital in controlling the duration of the early inflammatory response, thus restricting damage to tissues by the neutrophils. ANCA may be developed either via ineffective apoptosis or ineffec... | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-Role in disease-Disease associations ANCAs are associated with small vessel vasculitides including granulomatosis with polyangiitis, microscopic polyangiitis, primary pauci-immune necrotizing crescentic glomerulonephritis (a type of renal-limited microscopic polyangiitis), eosinophi... | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-Role in disease-Pathogenesis Although the pathogenic role of ANCA is still controversial, in vitro and animal models support the idea that the antibodies have a direct pathological role in the formation of small vessel vasculitides. MPO and PR3 specific ANCA can activate neutrophils... | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-Role in disease-Treatment Avacopan was approved for medical use in the United States to treat anti-neutrophil cytoplasmic autoantibody-associated vasculitis in October 2021. | milkshake721/2.1M-wiki-STEM |
Anti-neutrophil cytoplasmic antibody-History-ANCAs were originally described in Davies et al. in 1982 in segmental necrotising glomerulonephritis. The Second International ANCA Workshop, held in The Netherlands in May 1989, fixed the nomenclature on perinuclear vs. cytoplasmic patterns, and the antigens MPO and PR3 wer... | milkshake721/2.1M-wiki-STEM |
Developer Certificate of Origin-Developer Certificate of Origin-The Developer Certificate of Origin (DCO) is a statement that a software developer agrees to, saying that "the contributor is allowed to make the contribution and that the project has the right to distribute it under its license." It was introduced in 2004... | milkshake721/2.1M-wiki-STEM |
Developer Certificate of Origin-Developer Certificate of Origin-Developer Certificate of Origin Version 1.1 Copyright (C) 2004, 2006 The Linux Foundation and its contributors.
1 Letterman Drive Suite D4700 San Francisco, CA, 94129 Everyone is permitted to copy and distribute verbatim copies of this license document, bu... | milkshake721/2.1M-wiki-STEM |
Developer Certificate of Origin-Developer Certificate of Origin-Developer's Certificate of Origin 1.1 By making a contribution to this project, I certify that: (a) The contribution was created in whole or in part by me and I have the right to submit it under the open source license indicated in the file; or (b) The con... | milkshake721/2.1M-wiki-STEM |
Developer Certificate of Origin-Developer Certificate of Origin-(d) I understand and agree that this project and the contribution are public and that a record of the contribution (including all personal information I submit with it, including my sign-off) is maintained indefinitely and may be redistributed consistent w... | milkshake721/2.1M-wiki-STEM |
GO64-GO64-GO-64! was an early software emulation of the Commodore 64 computer, with a copyright date of 1988 for version 2.0.
The name most likely comes from the ability for the Commodore 128 computer to switch to a hardware emulation of the Commodore 64 by typing GO64 at the BASIC prompt and pressing the return key.
T... | milkshake721/2.1M-wiki-STEM |
McASP-McASP-McASP is an acronym for Multichannel Audio Serial Port, a communication peripheral found in Texas Instruments family of digital signal processors (DSPs) and Microcontroller Units (MCUs).
The McASP functions as a general-purpose audio serial port optimized for the needs of multichannel audio applications.
De... | milkshake721/2.1M-wiki-STEM |
McASP-McASP-The McASP consists of transmit and receive sections that may operate synchronized, or completely independently with separate master clocks, bit clocks, and frame syncs, and using different transmit modes with different bit-stream formats. The McASP module also includes up to 16 serializers that can be indiv... | milkshake721/2.1M-wiki-STEM |
McASP-Features-Features of the McASP include: Two independent clock generator modules for transmit and receive Clocking flexibility allows the McASP to receive and transmit at different rates. For example, the McASP can receive data at 48 kHz but output up-sampled data at 96 kHz or 192 kHz. | milkshake721/2.1M-wiki-STEM |
McASP-Features-Independent transmit and receive modules, each includes: Programmable clock and frame sync generator TDM streams from 2 to 32, and 384 time slots Support for time slot sizes of 8, 12, 16, 20, 24, 28, and 32 bits Data formatter for bit manipulation Individually assignable serial data pins (up to 16 pins) ... | milkshake721/2.1M-wiki-STEM |
McASP-Features-Wide variety of I2S and similar bit-stream format Integrated digital audio interface transmitter (DIT) supports: S/PDIF, IEC60958-1, AES-3 formats Up to 16 transmit pins Enhanced channel status/user data RAM 384-slot TDM with external digital audio interface receiver (DIR) device For DIR reception, an ex... | milkshake721/2.1M-wiki-STEM |
McASP-Features-Extensive error checking and recovery Transmit underruns and receiver overruns due to the system not meeting real-time requirements Early or late frame sync in TDM mode Out-of-range high-frequency master clock for both transmit and receive External error signal coming into the AMUTEIN input DMA error due... | milkshake721/2.1M-wiki-STEM |
McASP-Protocols-The McASP supports a wide variety of protocols. | milkshake721/2.1M-wiki-STEM |
McASP-Protocols-Transmit section supports Wide variety of I2S and similar bit-stream formats TDM streams from 2 to 32 time slots S/PDIF, IEC60958-1, AES-3 formats Receive section supports Wide variety of I2S and similar bit-stream formats TDM streams from 2 to 32 time slots TDM stream of 384 time slots specifically des... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Triple-negative breast cancer-Triple-negative breast cancer (TNBC) is any breast cancer that either lacks or shows low levels of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) overexpression and/or gene amplification (i.e. the tumor i... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Risk factors-The overall proportion of TNBC is very similar in all age groups. Younger women have a higher rate of basal or BRCA related TNBC, while older women have a higher proportion of apocrine, normal-like and rare subtypes including neuroendocrine TNBC.A study in the US has shown tha... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Classification-Breast cancer classification is used to assess the tumor to decide on treatment and prognosis. Classification can be performed using molecular, immunohistochemical, and clinical characteristics. One of the important classification types is receptor status, because it identif... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Classification-The basal-like subtype has many overlapping features to TNBC and in addition to being receptor negative, has increased expression of basal cytokeratins. 85% of basal-like tumors are TNBC.Subtypes are used to try to define better treatments or a more accurate prognosis. Howev... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Prognosis-TNBC is more likely to recur within the first five years after treatment than other breast cancers. However, after five years the chance of recurrence is much less than for other breast cancers. The risk of recurrence peaks at three years from diagnosis and reduces after that.Can... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Prognosis-Approximately 25% of those with localised disease will relapse with distant metastasis also known as stage IV. Median survival from diagnosis of metastasis is around 12 months. Metastasis in TNBC is different from other breast cancers with a tendency to spread to the brain and ot... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Treatment-Early stage disease Standard treatment is surgery with adjuvant chemotherapy and radiotherapy. | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Treatment-Surgery is primarily used for early stage disease and may be either a lumpectomy or a mastectomy. Studies have found that the overall survival for lumpectomy and radiotherapy was the same or higher than for a mastectomy for TNBC patients.Neoadjuvant chemotherapy (before surgery) ... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Treatment-Early stage TNBC is generally very susceptible to chemotherapy and can lead to a pathological complete response (pCR) i.e. no detectable cancer cells in the breast or lymph nodes. Although this does not always translate into overall survival.
Chemotherapy used to treat early stag... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Treatment-Treatment depends on whether the tumour tests positive for the programmed death cell ligand 1 (PD-L1) protein or BRCA gene mutation. Also known as immunotherapy the presence of PD-L1 on cancer cells mates with an associate PD-1 receptor on the bodies own immune killer T cells whi... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Treatment-The following treatment is recommended by the American Society of Clinical Oncology (ASCO) for metastatic TNBC: mTNBC +PD-L1: 1st line: offered chemo + immune checkpoint inhibitor mTNBC -PD-L1: 1st line: single-agent chemo; 3rd line: sacituzumab govitecan mTNBC +BRCA: patients pr... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Clinical trials-Angiogenesis and EGFR (HER-1) inhibitors are frequently tested in experimental settings and have shown efficacy. Treatment modalities are not sufficiently established for normal use, and it is unclear in which stage they are best used and which patients would profit. | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Clinical trials-By 2009 A number of new strategies for TNBC were being tested in clinical trials, including the PARP inhibitor BSI 201, NK012.A novel antibody-drug conjugate known as glembatumumab vedotin (CDX-011), which targets the protein GPNMB, has also shown encouraging clinical trial... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Research-Triple-negative breast cancers (TNBC) have, on average, significantly higher fluorine-18 fluorodeoxyglucose (FDG) uptake (measured by the SUVmax values) compared with uptake in ER+/PR+/HER2- tumors using fluorine-18 fluorodeoxyglucose-positron emission tomography (FDG-PET).
It is ... | milkshake721/2.1M-wiki-STEM |
Triple-negative breast cancer-Research-The widely used diabetes drug, metformin, holds promise for the treatment of triple-negative breast cancer. In addition metformin may influence cancer cells through indirect (insulin-mediated) effects, or it may directly affect cell proliferation and apoptosis of cancer cells. Epi... | milkshake721/2.1M-wiki-STEM |
Adenylosuccinate synthase-Adenylosuccinate synthase-In molecular biology, adenylosuccinate synthase (or adenylosuccinate synthetase) (EC 6.3.4.4) is an enzyme that plays an important role in purine biosynthesis, by catalysing the guanosine triphosphate (GTP)-dependent conversion of inosine monophosphate (IMP) and aspar... | milkshake721/2.1M-wiki-STEM |
Adenylosuccinate synthase-Structure-The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections bet... | milkshake721/2.1M-wiki-STEM |
Adenylosuccinate synthase-Isozymes-Humans express two adenylosuccinate synthase isozymes: | milkshake721/2.1M-wiki-STEM |
Zero ionic layer-Zero ionic layer-Zero ionic layer is the main site of interaction in the core SNARE complex. Dipole-dipole interactions take place between 3 glutamine (Q) residues and 1 arginine (R) residue exposed in this layer. Despite that, the majority of the SNARE complex is hydrophobic because of the leucine zip... | milkshake721/2.1M-wiki-STEM |
Zero ionic layer-Structure-SNARE complex is a bundle formed by 4 alpha-helical proteins, including vesicle-associated Synaptobrevin and cell-membrane-associated Syntaxin and SNAP. When the bundle is viewed on the side, for every alpha-helical turn, the alpha-carbons from each helix form a plane, which is thus designate... | milkshake721/2.1M-wiki-STEM |
Zero ionic layer-Function and research interest-SNARE proteins are a family of a proteins that are located in cell membranes to mediate any secretory pathways. The complex is formed during exocytosis, a process where the vesicles inside the cell fuse with the cell membrane to secrete molecules into the extracellular sp... | milkshake721/2.1M-wiki-STEM |
Zero ionic layer-Mutation and alternation-In studies that use exocytotic SNAREs of yeast as models, a mutation from glutamine to arginine in the zero ionic layer leads to yeast cells that have deficient growth and protein secretion ability. However, a mutation from arginine to glutamine in this layer leads to yeast cel... | milkshake721/2.1M-wiki-STEM |
Congenital distal spinal muscular atrophy-Congenital distal spinal muscular atrophy-Congenital distal spinal muscular atrophy is a hereditary condition characterized by muscle wasting (atrophy), particularly of distal muscles in legs and hands, and by early-onset contractures (permanent shortening of a muscle or joint)... | milkshake721/2.1M-wiki-STEM |
Congenital distal spinal muscular atrophy-Signs and symptoms-The presentation is as follows: Neurogenic muscle weakness Atrophy (of lower and upper limbs) Club foot Arthrogryposis Scoliosis Platyspondyly Pes cavus Vocal cord paralysis | milkshake721/2.1M-wiki-STEM |
Congenital distal spinal muscular atrophy-Causes-Congenital distal spinal muscular atrophy is caused by a mutation of the TRPV4 gene found on the 12q23-12q24.1. The mutation causes an affected individual to have lower levels of TRPV4 expression. This deficiency can lead to abnormal osmotic regulation. Congenital dSMA i... | milkshake721/2.1M-wiki-STEM |
Congenital distal spinal muscular atrophy-Pathophysiology-The TRPV4 (transient receptor potential vanilloid 4) gene, located on chromosome 12, encodes for a protein that serves as an ion channel, typically found in the plasma membrane and is permeable to Ca2+. Abnormal regulation of Ca2+ can lead to inefficient muscle ... | milkshake721/2.1M-wiki-STEM |
Congenital distal spinal muscular atrophy-Pathophysiology-Mechanism The ankyrin repeat domain (ARD) is a region located near the intracellular N-terminal of the TRPV4 protein and consists of six ankyrin repeats. Four missense mutations have been identified at three specific positions all located within the ARD. All of ... | milkshake721/2.1M-wiki-STEM |
Congenital distal spinal muscular atrophy-Diagnosis-Electrophysiological evidence of denervation with intact motor and sensory nerve conduction findings must be made by using nerve conduction studies, usually in conjunction with EMG. The presence of polyphasic potentials and fibrillation at rest are characteristic of c... | milkshake721/2.1M-wiki-STEM |
Congenital distal spinal muscular atrophy-Management-Congenital dSMA has a relatively stable disease course, with disability mainly attributed to increased contractures rather than loss of muscle strength. Individuals frequently use crutches, knee, ankle, and/or foot orthoses, or wheelchairs. Orthopaedic surgery can be... | milkshake721/2.1M-wiki-STEM |
DT Carnage-DT Carnage-DT Carnage is a racing game developed by South Korean studio Axis Entertainment. The Nintendo Wii release was cancelled. | milkshake721/2.1M-wiki-STEM |
DT Carnage-Plot-The game revolves around a fictional tournament called the DT Tournament where people race using modified cars and are allowed the use of weapons. The player's father is injured in one of the tournaments, and the player swears revenge against the one who injured him. | milkshake721/2.1M-wiki-STEM |
DT Carnage-Features-Allows the player to use items to slow down opponents Crush other drivers against the side of the track RPG mode - use various items and techniques to excel on the track. | milkshake721/2.1M-wiki-STEM |
Congenital epulis-Congenital epulis-Congenital epulis is a proliferation of cells most frequently occurring on the alveolar ridge of the upper jaw at birth. Less frequently, the mass may arise from the mandibular alveolus. Rare cases can arise from the tongue. This lesion is more commonly found in female babies, sugges... | milkshake721/2.1M-wiki-STEM |
Congenital epulis-Congenital epulis-Multiple lesions occur in 10% of affected neonates. The tumor is typically pedunculated and varies in maximum size from 0.5 cm to 9 cm. The lesion is typically painless and does not increase in size after discovery. Some small lesions may regress over time. Treatment is surgical exci... | milkshake721/2.1M-wiki-STEM |
DYNLT1-DYNLT1-Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group ... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Radio propaganda-Radio propaganda is propaganda aimed at influencing attitudes towards a certain cause or position, delivered through radio broadcast. The power of radio propaganda came from its revolutionary nature. The radio, like later technological advances in the media, allowed information to be t... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Radio propaganda-Before television, radio was by far the most effective way to prevent or promote social change. In many areas, it still is. Radio propaganda can be broadcast over great distances to a large audience at a relatively low cost. Through radio, a propagandist can bring his voice and all the... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-World War II-The use of radio as a wartime propaganda tool was made famous during World War II by broadcasting organizations such as Voice of America and by shows such as Tokyo Rose, Axis Sally, and Lord Haw Haw. | milkshake721/2.1M-wiki-STEM |
Radio propaganda-World War II-Nazi Germany The radio was an important tool of the Nazi propaganda efforts and it has been argued that it was the Nazis who pioneered the use of what was still a relatively new technology. A few months after the break out of World War II, German propagandists were transmitting no less tha... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-World War II-German propaganda minister, Joseph Goebbels, claimed the radio was the "eighth great power" and he, along with the Nazi party, recognized the power of the radio in the propaganda machine of Nazi Germany. Recognizing the importance of radio in disseminating the Nazi message, Goebbels approv... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-World War II-United Kingdom British propaganda during the First World War set a new benchmark that inspired the fascist and socialist regimes during the Second World War and the Cold War; Marshal Paul von Hindenburg stated, "This English propaganda was a new weapon, or rather a weapon which had never b... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-World War II-"Yesterday, December 7th, 1941 – a date which will live in infamy – the United States of America was suddenly and deliberately attacked by naval and air forces of the Empire of Japan. It will be recorded that the distance of Hawaii from Japan makes it obvious that the attack was deliberate... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-World War II-Famous radio shows During World War II, American GIs in both the Pacific and European theaters of war heard anonymous voices on the radio playing carefully selected American music and extolling the virtues of Japanese and Nazi causes. The DJs continuously encouraged GIs to stop fighting an... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-World War II-"Tokyo Rose": After being stranded in Japan while visiting her sick aunt after the United States refused to let her reenter the country after the attack on Pearl Harbor, Iva Toguri wound up at Radio Tokyo as a typist, preparing English-language scripts drafted by Japanese authorities for b... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-World War II-After the war, the Army Counter Intelligence Corps, the Federal Bureau of Investigation, and the press continued to refer to Toguri by that name as she was taken into custody and brought to trial. Those defending Toguri stated that she was clearly "forced" to broadcast for the Japanese and... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-World War II-"Axis Sally" was the pseudonym of Mildred Gillars, an American broadcaster employed by the Third Reich in Nazi Germany to proliferate propaganda during World War II. By 1941, the U.S. State Department advised American nationals to return home, but Gillars chose to stay in Germany after her... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-World War II-"Lord Haw-Haw" was a pseudonym for William Joyce, German radio's most prominent English-language speaker. He hosted a propaganda show on a radio program called Germany Calling, broadcast by Nazi German radio to audiences in the UK on the station Reichssender Hamburg. The program started on... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Cold War-By 1946, it became clear to the United States that the Soviet Union did not share the American vision of postwar collaboration for peace in Europe. Soviet authorities began to install Communist regimes in liberated territories of Eastern Europe, a direct violation of the provisions in the Tehe... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Cold War-Aside from RIAS, Voice of America (VOA) began broadcasting in 1947 in the Soviet Union for the first time as a part of U.S. foreign policy to fight the propaganda of the Soviet Union and other countries. Initially, there was only one hour per day of news and other features broadcast on the pre... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Cold War-2) Present America fairly and counter “all the misrepresentations.” 3) Discourage further Soviet encroachment by showing that American is desirous of peace but is prepared for war. | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Cold War-4) Help “to roll back Soviet influence” by all means short of force, making captive people feel that they can identify with the West, weakening the morale of the Soviet military personnel, and encouraging non-Communist forces.In late 1950, RFE/RL began to assemble a full-fledged foreign broadc... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Vietnam-The first Vietnamese-language radio transmission was made on 2 September 1945, when Ho Chi Minh read out the Declaration of Independence. Prior to 1945, Vietnamese people were banned from owning radio receivers, and broadcasting was under control of the French colonial government, which establi... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Vietnam-"Hanoi Hannah" or Trịnh Thị Ngọ, was a Vietnamese radio personality best known for her work during the Vietnam War, when she made English-language broadcasts for North Vietnam directed at U.S. troops. During the Vietnam War in the 1960s and 1970s, Ngo became famous among U.S. soldiers for her p... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Iraq and Afghanistan-The United States took the lead in broadcasting psychological operations due to its superior technology and its ability to use aircraft to broadcast AM, FM and shortwave radio from directly above target audiences. America had dropped battery or crank-powered radios on third-world n... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Iraq and Afghanistan-In the 2001 invasion of Afghanistan, psychological operations (PSYOP) tactics were employed to demoralize the Taliban and to win the sympathies of the Afghan population. At least six EC-130E Commando Solo aircraft were used to jam local radio transmissions and transmit replacement ... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Voice of America-Voice of America, The Voice, or VOA is the official external broadcast institution of the United States federal government, sponsoring programming for broadcast on the radio, television, and the Internet outside of the U.S. in 43 languages. Currently, VOA produces about 1,500 hours of ... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Voice of America-2. VOA will represent America, not any single segment of American society, and will therefore present a balanced and comprehensive projection of significant American thought and institutions. | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Voice of America-3. VOA will present the policies of the United States clearly and effectively, and will also present responsible discussions and opinion on these policies.”Today, the VOA operates shortwave radio transmitters and antenna farms at one site in the United States close to Greenville, North... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Voice of America-In 1994, Voice of America became the first broadcast-news organization to offer continuously updated programs on the Internet in English and 44 other languages, using more than 20,000 servers across 71 countries. Since many listeners in Africa and other areas still receive much of thei... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Radio Free Europe/Radio Liberty-Radio Free Europe/Radio Liberty is a broadcaster funded by the United States Congress that provides news, information, and analysis to countries in Eastern Europe, Central Asia, and the Middle East "where the free flow of information is either banned by government author... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Radio Free Europe/Radio Liberty-Founded as an anti-Communist propaganda source during the Cold War, RFE/RL was headquartered in Munich, Germany, from 1949 to 1995. In 1995, the headquarters were moved to Prague in the Czech Republic, where operations have been significantly reduced since the end of the... | milkshake721/2.1M-wiki-STEM |
Radio propaganda-Radio Free Europe/Radio Liberty-RFE/RL was developed out of a belief that the Cold War would eventually be fought by political rather than military means. American policymakers such as George Kennan and John Foster Dulles acknowledged that the Cold War was essentially a "war of ideas". The United State... | milkshake721/2.1M-wiki-STEM |
EIF4E-EIF4E-Eukaryotic translation initiation factor 4E, also known as eIF4E, is a protein that in humans is encoded by the EIF4E gene. | milkshake721/2.1M-wiki-STEM |
EIF4E-Structure and function-Most eukaryotic cellular mRNAs are blocked at their 5'-ends with the 7-methyl-guanosine five-prime cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nucl... | milkshake721/2.1M-wiki-STEM |
EIF4E-Structure and function-The other subunits of eIF4F are a 47-kD polypeptide, termed eIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD scaffolding polypeptide, eIF4G.Some viruses cut eIF4G in such a way that the eIF4E binding site is removed and the virus is able to translate its proteins witho... | milkshake721/2.1M-wiki-STEM |
EIF4E-Structure and function-eIF4E is found in the nucleus of many mammalian cell types as well as in other species including yeast, drosophila and humans. eIF4E is found in nuclear bodies a subset of which colocalize with PML nuclear bodies, and eIF4E is additionally found diffusely in parts of the nucleoplasm in mamm... | milkshake721/2.1M-wiki-STEM |
EIF4E-Regulation-Since eIF4E is an initiation factor that is relatively low in abundance, eIF4E can be controlled at multiple levels. Regulation of eIF4E may be achieved at the levels of transcription, RNA stability phosphorylation, subcellular localization and partner proteins.a. Regulation of eIF4E by Gene Expression... | milkshake721/2.1M-wiki-STEM |
EIF4E-Regulation-Recent studies shown that eIF4E levels can be regulated at transcriptional level by NFkB and C/EBP. Interestingly, transduction of primary AML cells with IkB-SR resulted not only in reduction of eIF4E mRNA levels, but also re-localization of eIF4E protein. eIF4E mRNA stability are also regulated by HuR... | milkshake721/2.1M-wiki-STEM |
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