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Interactive children's book-Pop-up books-Pop-up books are common enough to be found in your local library, bookstore, classroom, or likely even your own bookshelf. There are several examples of these kinds of books, but some famous ones to check out are: Christmas in New York by Chuck Fischer, Star Wars: A Pop-Up Guide... | milkshake721/2.1M-wiki-STEM |
Interactive children's book-Pop-up books-It wasn't until the late nineteenth century, partly due to the invention of industrial printing, that pop-ups were created. The first pop-up books published in America were those in the Showman Series published by the McLoughlin Brothers. Still, these books were too expensive an... | milkshake721/2.1M-wiki-STEM |
Interactive children's book-Digitized learning books-Many children's interactive books have been enhanced through the use of technology. The earliest examples of this were books that had sound effects- a bar on the side of the book that had buttons corresponding with pictures in the story. When the icon appeared in the... | milkshake721/2.1M-wiki-STEM |
Interactive children's book-Digitized learning books-Once computers became more prevalent, CD-ROM versions of books became popular. These were programs that put books on the computer screen, enabling children to click their way through various words and pictures in the story and have it come alive. The technology was f... | milkshake721/2.1M-wiki-STEM |
Interactive children's book-Digitized learning books-The goal for these products is to help children get more out of their books and learn to read, according to Leap Frog. Leap Frog even has its own publishing company, Leap Frog Press, which creates books specifically designed for its system. The products are not cheap... | milkshake721/2.1M-wiki-STEM |
Interactive children's book-Digitized learning books-Of course, Leap Frog is not the only company with products like the Leap Pad or Tag system that use technology to enhance the reading experience for children. However, it was one of the first, and now several companies have copied the idea and made similar products. | milkshake721/2.1M-wiki-STEM |
Interactive children's book-Digitized learning books-The newest advance in interactive children's books reflects the recent popularity of Amazon's Kindle. There are now a plethora of e-book sites that place children's picture books, along with LeapFrog-like sound effects and word pronunciation, completely online-often ... | milkshake721/2.1M-wiki-STEM |
Interactive children's book-Digitized learning books-Here are a few examples of some interactive e-book sites for children: Magic Keys Books Raz-Kids Books Tumble BooksEven older classic books are moving to online to keep up with the times. | milkshake721/2.1M-wiki-STEM |
Video+-Video+-Video+ (or Video+ Player on Google Play) is a video player and downloader that is developed and operated by LEO Network. The developer describes it as a video "hunter" or "seeker" where to explore one’s interests and discover the neighborhood. | milkshake721/2.1M-wiki-STEM |
Video+-Description-Video+ works as a sniffer to allow users to discover video collections from nearby people. It was featured on the location-based media sharing and discovering function. Location-based service (LBS) was first applied by the biggest and fastest growing Location-Based Social Network – Foursquare and bec... | milkshake721/2.1M-wiki-STEM |
Video+-Supported Formats-mkv, avi, flv, rm, rmvb, asf, asx, mov, mpe, ts, vob, wmv, f4v, vp, mpeg, mpg, m4v, mp4, 3gp, 3gpp, 3g2, 3gpp2 | milkshake721/2.1M-wiki-STEM |
Video+-Technologies-According to Sem, one of LEO’s most contributed developers: Video+ was implemented with the self-developed “Air-Link Multi-connectional Wireless Transmission” technology, which combines Wi-Fi with Bluetooth and requires no internet connection during the downloading process. | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Adipose tissue-Adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes. In addition to adipocytes, adipose tissue contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-In humans, adipose tissue is located: beneath the skin (subcutaneous fat), around internal organs (visceral fat), in bone marrow (yellow bone marrow), intermuscular (Muscular system) and in the breast (breast tissue). Adipose tissue is found in specific locations, which are referred t... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-Adipose tissue contains many small blood vessels. In the integumentary system, which includes the skin, it accumulates in the deepest level, the subcutaneous layer, providing insulation from heat and cold. Around organs, it provides protective padding. However, its main function is to... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-Mice Mice have eight major adipose depots, four of which are within the abdominal cavity. The paired gonadal depots are attached to the uterus and ovaries in females and the epididymis and testes in males; the paired retroperitoneal depots are found along the dorsal wall of the abdome... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-The two superficial depots are the paired inguinal depots, which are found anterior to the upper segment of the hind limbs (underneath the skin) and the subscapular depots, paired medial mixtures of brown adipose tissue adjacent to regions of white adipose tissue, which are found unde... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-Obesity In an obese person, excess adipose tissue hanging downward from the abdomen is referred to as a panniculus. A panniculus complicates surgery of the morbidly obese individual. It may remain as a literal "apron of skin" if a severely obese person loses large amounts of fat (a co... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-Visceral fat Visceral fat or abdominal fat (also known as organ fat or intra-abdominal fat) is located inside the abdominal cavity, packed between the organs (stomach, liver, intestines, kidneys, etc.). Visceral fat is different from subcutaneous fat underneath the skin, and intramusc... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-Epicardial fat Epicardial adipose tissue (EAT) is a particular form of visceral fat deposited around the heart and found to be a metabolically active organ that generates various bioactive molecules, which might significantly affect cardiac function. Marked component differences have ... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-Subcutaneous fat Most of the remaining nonvisceral fat is found just below the skin in a region called the hypodermis. This subcutaneous fat is not related to many of the classic obesity-related pathologies, such as heart disease, cancer, and stroke, and some evidence even suggests it... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-Marrow fat Marrow fat, also known as marrow adipose tissue (MAT), is a poorly understood adipose depot that resides in the bone and is interspersed with hematopoietic cells as well as bony elements. The adipocytes in this depot are derived from mesenchymal stem cells (MSC) which can g... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-Ectopic fat Ectopic fat is the storage of triglycerides in tissues other than adipose tissue, that are supposed to contain only small amounts of fat, such as the liver, skeletal muscle, heart, and pancreas. This can interfere with cellular functions and hence organ function and is ass... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Anatomical features-The specific cause for the accumulation of ectopic fat is unknown. The cause is likely a combination of genetic, environmental, and behavioral factors that are involved in excess energy intake and decreased physical activity. Substantial weight loss can reduce ectopic fat stores in al... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-Free fatty acids (FFAs) are liberated from lipoproteins by lipoprotein lipase (LPL) and enter the adipocyte, where they are reassembled into triglycerides by esterifying them onto glycerol. Human fat tissue contains about 87% lipids.There is a constant flux of FFAs entering and leaving adipose... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-Fat cells have an important physiological role in maintaining triglyceride and free fatty acid levels, as well as determining insulin resistance. Abdominal fat has a different metabolic profile—being more prone to induce insulin resistance. This explains to a large degree why central obesity i... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-Brown fat Brown fat or brown adipose tissue (BAT) is a specialized form of adipose tissue important for adaptive thermogenesis in humans and other mammals. BAT can generate heat by "uncoupling" the respiratory chain of oxidative phosphorylation within mitochondria through tissue-specific expre... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-Beige fat and WAT browning Browning of WAT, also referred to as "beiging", occurs when adipocytes within WAT depots develop features of BAT. Beige adipocytes take on a multilocular appearance (containing several lipid droplets) and increase expression of uncoupling protein 1 (UCP1). In doing s... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-The calorie-burning capacity of brown and beige fat has been extensively studied as research efforts focus on therapies targeted to treat obesity and diabetes. The drug 2,4-dinitrophenol, which also acts as a chemical uncoupler similarly to UCP1, was used for weight loss in the 1930s. However,... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-Genomics and bioinformatics tools to study browning Due to the complex nature of adipose tissue and a growing list of browning regulatory molecules, great potential exists for the use of bioinformatics tools to improve study within this field. Studies of WAT browning have greatly benefited fro... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-DNA microarray is a bioinformatics tool used to quantify expression levels of various genes simultaneously, and has been used extensively in the study of adipose tissue. One such study used microarray analysis in conjunction with Ingenuity IPA software to look at changes in WAT and BAT gene ex... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-RNA sequencing (RNA-Seq) is a powerful computational tool that allows for the quantification of RNA expression for all genes within a sample. Incorporating RNA-Seq into browning studies is of great value, as it offers better specificity, sensitivity, and a more comprehensive overview of gene e... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-Chromatin immunoprecipitation with sequencing (ChIP-seq) is a method used to identify protein binding sites on DNA and assess histone modifications. This tool has enabled examination of epigenetic regulation of browning and helps elucidate the mechanisms by which protein-DNA interactions stimu... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-Genetics The thrifty gene hypothesis (also called the famine hypothesis) states that in some populations the body would be more efficient at retaining fat in times of plenty, thereby endowing greater resistance to starvation in times of food scarcity. This hypothesis, originally advanced in th... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-Leptin, however, plays a different role in diet-induced obesity in rodents and humans. Because adipocytes produce leptin, leptin levels are elevated in the obese. However, hunger remains, and—when leptin levels drop due to weight loss—hunger increases. The drop of leptin is better viewed as a ... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Physiology-Physical properties Adipose tissue has a density of ~0.9 g/ml. Thus, a person with more adipose tissue will float more easily than a person of the same weight with more muscular tissue, since muscular tissue has a density of 1.06 g/ml. | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Body fat meter-A body fat meter is a tool used to measure the body fat to weight ratio in the human body. Different meters use various methods to determine the ratio. They tend to under-read body fat percentage. | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Body fat meter-In contrast with clinical tools, one relatively inexpensive type of body fat meter uses the principle of bioelectrical impedance analysis (BIA) in order to determine an individual's body fat percentage. To achieve this, the meter passes a small, harmless, electric current through the body ... | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Body fat meter-Before bioelectrical impedance analysis machines were developed, there were many different ways in analyzing body composition such as skin fold methods using calipers, underwater weighing, whole body air displacement plethysmography (ADP) and DXA. | milkshake721/2.1M-wiki-STEM |
Adipose tissue-Animal studies-Within the fat (adipose) tissue of CCR2 deficient mice, there is an increased number of eosinophils, greater alternative Macrophage activation, and a propensity towards type 2 cytokine expression. Furthermore, this effect was exaggerated when the mice became obese from a high fat diet. | milkshake721/2.1M-wiki-STEM |
Task Force on Process Mining-Task Force on Process Mining-The IEEE Task Force on Process Mining (TFPM) is a non-commercial association for process mining. The IEEE (Institute of Electrical and Electronics Engineers) Task Force on Process Mining was established in October 2009 as part of the IEEE Computational Intellige... | milkshake721/2.1M-wiki-STEM |
Task Force on Process Mining-Activities and organization-The Task Force on Process Mining has a Steering Committee and an Advisory Board. The Steering Committee, chaired by Wil van der Aalst since its inception in 2009, defined 15 action lines. These include the organization of the annual International Process Mining C... | milkshake721/2.1M-wiki-STEM |
Task Force on Process Mining-Activities and organization-In 2016, the IEEE Standards Association published the IEEE Standard for Extensible Event Stream (XES), which is a widely accepted file format by the process mining community. | milkshake721/2.1M-wiki-STEM |
Task Force on Process Mining-Supporting organizations-The Task Force on Process Mining is supported by most of the process mining vendors (e.g., Celonis, Fluxicon, UiPath, QPR, ABBYY, LANA, Logpicker, Minit, Myinvenio, PAFnow, Signavio and Software AG), consultancy firms (KPMG, Deloitte, etc.), universities (e.g., RWTH... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Euchre variants-The card game of Euchre has many variants, including those for two, three, five or more players. The following is a selection of notable Euchre variants. | milkshake721/2.1M-wiki-STEM |
Euchre variants-Two-player variants-Two-player dummy A normal hand is dealt out to each player along with a 3-card dummy hand to each player. Each person picks up their dummy hand after trump has been called. Each player must make their best five card hand out of the eight cards available.
Going alone is still an optio... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Two-player variants-A normal deck of 9-10-J-Q-K-A in all four suits is used. The dealer places a card face down in front of the other player, and then in front of the dealer, alternating until each player has a row of four face-down cards. The dealer then places a face-up card on top of each face-down c... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Two-player variants-The non-dealer looks at their 4 hand cards, 4 show cards, and the opponents 4 show cards, and bids the number of tricks they think they can take, with a minimum bid of 7. The dealer can bid higher or pass. The highest bidder sets the trump suit, and the non-dealer goes first.
Players... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Two-player variants-It is strategically important to remember to keep cards in the hand, as otherwise it is very easy for the opponent to lead off-suit and win. It may thus be better in cases to sacrifice a higher-value face-up card than to give up hand cards. Similarly, if out of trump cards, it may be... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Two-player variants-Points are only awarded or lost for the number of tricks bid: 1 point for 7 tricks, 2 points for 8 tricks, etc., up to 6 points for all 12 tricks. The player who bid gains the points if they succeed, and loses the points if they fail. The first player to get 10 points wins the game.
... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Missing Man Missing Man Euchre (a.k.a. George's Hand Euchre) is a three-handed Euchre tournament game of Western Wisconsin. It is also played on the gulf coast of Florida. It plays similarly to traditional four-handed Euchre. | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Four 5-card Euchre hands are dealt with the fourth hand being a dummy (sometimes called George's Hand), and the top card of the remaining cards is upturned. The trump suit is called in the normal fashion, in two rounds of bidding. However, either of the players who does not call tr... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Play proceeds as normal. The calling player scores 1 point for 3 or 4 tricks, 2 points for all 5 tricks, and 4 points for a called loner. If the calling player fails to win the bid, the other players score 1 point each.
Since the caller has no partner, leading trump is a good strat... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Three-hand dummy Another common three-player variation is played by dealing out four hands, but with the fourth hand acting as a dummy hand (a.k.a. the dead hand, imaginary friend, George, Johann, etc.). After calling trump, the calling player picks up the dummy hand and makes the ... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Variations may limit the size or utility of the dummy hand, because making the best hand from ten cards may be viewed as too advantageous. Examples include a three-card dummy or the calling player randomly choosing three cards from the dummy, then making the best hand out of eight ... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Sneaky Steve is a variant in which the dummy hand is called "Steve". After the trump is called and the 5-card dummy hand is used or discarded, the player with the 9 of diamonds (called "Sneaky Steve") may exchange it for a random card of the 3 bottom cards of the kitty (i.e.: not ... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Cut-throat Euchre In Cut-throat Euchre, the dealing and bidding process is as normal. The caller scores 1 point for 3 or 4 tricks, 3 points for 5 tricks, and the defenders each get 2 points for 3 or more tricks.
Strategy is similar to going alone in standard Euchre. Defenders shoul... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Count down – With the 9s removed from the deck, players start at 300 or 500 points and play down. Points are inflated: the caller loses 10 points for 3 or 4 tricks, 50 points for all 5 tricks, and the defenders each lose 20 points for 3 or more tricks. The first player to lose all ... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Canadian In western New York, a three-player variation called "Canadian" is played (it is called Gyoza in Chicago and Buck Euchre in areas of the US Midwest). Four hands are dealt normally. The top kitty card is upturned and automatically becomes trump. Starting from the dealer's l... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Shooter In Southern Ontario, a three-person version exists called "Shooter". Three eight-card hands are dealt. Players then bid to call trump, with a minimum bid of 3 tricks. The winner of the contract calls the trump suit or may call "no trump", where aces are high and all jacks a... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Ghost player Four 5-card hands are dealt, with the extra hand going to the "ghost player". In clockwise order, players may opt to switch their hand with the ghost player's hand. The top card of the kitty is then upturned and bidding and play proceed as normal. If the caller played ... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Threechre In Threechre (sometimes pronounced "tree-ker" or "three-kree"), only three suits are used and a joker serves as the left bower, regardless of drawn suit. The dealer may opt to go alone in the first round of bidding, in which case the top card is discarded and the remainin... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Call-partner Call-partner is a variation for 3 to 10 players (using a deck adjusted so that the kitty will have 5 cards or less after dealing a 5-card hand to each player). The top card of the kitty is upturned and bidding proceeds as normal. The player who calls trump may call for... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Three-player variants-Euchress Euchress discards the 9s from the deck. Dealing and bidding are as normal, but the caller can choose a partner or go alone. Scoring is the same, with play typically going to 15 points. | milkshake721/2.1M-wiki-STEM |
Euchre variants-Four-player variations-Benny variants A common variant played in southwestern England pub leagues uses the standard Euchre deck with an extra card, usually a Joker or 2 of spades, called the "Benny" (or the "Bird" in Australia). This card is the highest trump no matter what suit is called. When the Benn... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Four-player variations-The Duchy of Cornwall lays claim to the origin of the Benny in Euchre, its usage being exported by emigrant Cornish miners in the eighteenth and nineteenth centuries. | milkshake721/2.1M-wiki-STEM |
Euchre variants-Four-player variations-Railroad Euchre There is an extension of this style wherein the 9s are removed from the deck and up to four "Bennys" are added (usually one or both jokers and/or one or both deuces). In its simplest form, with a single Benny, it is the same as the English variant (above). The Benn... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Four-player variations-Although somewhat complicated, the addition of up to four higher-ranking trump cards makes a significant strategic impact on gameplay. The two and three Benny versions are the most common. | milkshake721/2.1M-wiki-STEM |
Euchre variants-Four-player variations-33-card deck In Guernsey (Channel Islands) the game is played with a 33 card deck incorporating 7 to Ace plus a joker as Benny. In addition, where the Benny is turned up, the dealer not only has to name the suit, he must then pick it up and play (although he may still choose wheth... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Four-player variations-Haus or Hoss Haus or Hoss is a variant popular in parts of upstate New York, specifically the Pennsylvania Dutch area. Two standard decks are used with the numeral cards removed to leave only the Aces and court cards. Players form two teams of two, sitting opposite one another. De... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Five players-One five-player variant expands the standard deck, adding the 8s and a pair of 2s (or alternatively the jokers). The 2s or jokers are the highest trump cards, whichever suit is called. Five 5-card hands are dealt and the top card of the kitty is upturned. If no other player orders a trump s... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Six-player variants-Uneven Teams The above rules for five-handed euchre can also be used for 6 hands by adding the 7s. The team that makes trump will usually play 2 against 4. | milkshake721/2.1M-wiki-STEM |
Euchre variants-Six-player variants-Triple Wild Deck Partnerships are two teams of three players. The deck consists of 8s through aces, with the addition of the 4, 3, and 2 of spades which are (in order) the highest trumps. After dealing, there is a single card left over which serves as the top card for bidding. The ga... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Six-player variants-32-card deck Partnerships are three teams of two players seated across from each other. The deck is 32 cards, 7 through ace of each suit. The kitty consists of only two cards. If defenders euchre the callers, both defending teams score 2 points. The game is won when the first team sc... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Six-player variants-34-card deck Partnerships are two teams of three players. The deck consists of 7s through aces plus two jokers, which are the highest and second-highest trumps. | milkshake721/2.1M-wiki-STEM |
Euchre variants-Six-player variants-Six-suit deck Partnerships are three teams of two players, seated opposite. Uses a deck constructed of three red suits and three black suits, such that there is one right bower and two left bowers (the first left bower played outranks the second). Bidding, play, and scoring is as nor... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Six-player variants-Double deck Partnerships are two teams of three players. Uses two standard euchre decks (48 cards); if the same card is played twice in a trick, the card which is played first is highest. Each player is dealt 8 cards. Players bid how many tricks they can get (minimum 3), with the win... | milkshake721/2.1M-wiki-STEM |
Euchre variants-Six-player variants-Teams score 1 point for each trick won. If a team fails to make its bid, they don't receive any points and additionally lose the same number of points as their bid. Winning all 8 tricks scores an additional 4 points on a Little Shooter and 16 points on a Big Shooter. The game is won ... | milkshake721/2.1M-wiki-STEM |
Heuristic (engineering)-Heuristic (engineering)-In engineering, heuristics are experience-based methods used to reduce the need for calculations pertaining to equipment size, performance, or operating conditions. Heuristics are fallible and do not guarantee a correct solution. It is important to understand their limita... | milkshake721/2.1M-wiki-STEM |
Heuristic (engineering)-Heuristic (engineering)-Problem solving methods are intrinsic to forensic engineering methods, where failures are analysed for the root cause or causes. Only when failures have been investigated with conclusive results can remedial action be taken with confidence. | milkshake721/2.1M-wiki-STEM |
Heuristic (engineering)-Examples-Storage Vessels These heuristics were taken from Turton's "Analysis, Synthesis, and Design of Chemical Processes".
Use vertical tanks on legs when the tank is less than 3.8 m3.
Use horizontal tanks on concrete supports when the tank is between 3.8 and 38 m3, Use vertical tanks on concre... | milkshake721/2.1M-wiki-STEM |
Burger Rings-Burger Rings-Burger Rings are a type of corn-based, burger-flavoured Australian snack food distributed by The Smith's Snackfood Company, which, in turn is owned by PepsiCo. | milkshake721/2.1M-wiki-STEM |
Burger Rings-History-Burger Rings were introduced in 1974.During the late 1990s the Burger Rings brand went through a brand overhaul, coinciding with the acquisition of The Smith's Snackfood Company by Lays. During the brand overhaul the appearance of the packet was changed to a more modernised look with bolder and sha... | milkshake721/2.1M-wiki-STEM |
Burger Rings-Ingredients-Burger Rings are made out of a combination of corn and rice. A Smith's Chips representative confirmed Burger Rings are suitable for vegans.The ingredients for Burger Rings are as follows: cereals (corn, rice), vegetable oil, maltodextrin, rice bran, salt, sugar, hydrolysed vegetable protein (so... | milkshake721/2.1M-wiki-STEM |
Burger Rings-Flavours-A Bacon Flavour variant was offered in Australia, briefly. | milkshake721/2.1M-wiki-STEM |
Burger Rings-Marketing-A memorable Star Wars-themed advertisement for the product was aired on Australian television in the early 1980s. It featured a faux Luke Skywalker character on Tatooine. After exiting his Landspeeder, he is confronted by a large group of Jawas who ask for his Burger Rings. He begrudgingly shares... | milkshake721/2.1M-wiki-STEM |
Burger Rings-Marketing-A radio ad campaign in the 1980s joked that Burger Rings were possibly made of rubber tyres concluding with the slogan "they taste good but!". | milkshake721/2.1M-wiki-STEM |
Burger Rings-Marketing-A 1989 ad aired on Australian television depicting a school chemistry experiment resulting in the creation of a single Burger Ring snack. The student who performed the experiment consumes the snack and seems to gain superpowers, developing jagged hair and a crazed look as the now-fluorescent Burg... | milkshake721/2.1M-wiki-STEM |
Burger Rings-In popular culture-In 2014, a contestant on Australian quiz show Millionaire Hot Seat failed to identify "Burger ring" as the "gag answer" to the $100 question, "Which of these is not a piece of jewellery commonly worn to symbolise a relationship between two people?". The contestant instead incorrectly loc... | milkshake721/2.1M-wiki-STEM |
Burger Rings-International variants-Burger Rings are available in New Zealand under the same name, except distributed by Bluebird Foods. The New Zealand variant has a different packaging design and a similar slogan: "Full on burger flavour". They are available in 30g and 120g bags, and in 108g 6-pack multipacks. | milkshake721/2.1M-wiki-STEM |
TRIM63-TRIM63-E3 ubiquitin-protein ligase TRIM63, also known as "MuRF1" (Muscle Ring-Finger Protein-1), is an enzyme that in humans is encoded by the TRIM63 gene.This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M... | milkshake721/2.1M-wiki-STEM |
TRIM63-Interactions-Trim63/MuRF1 has been shown to be an E3 ubiquitin ligase. Its major substrate is Myosin Heavy Chain (MHC, or Myosin-2, or MYH2), meaning it induces the proteasome-mediated degradatin of MHC, by causing MHC to be ubiquitinated. MuRF1 is upregulated during skeletal muscle atrophy – and thus the degrad... | milkshake721/2.1M-wiki-STEM |
TRIM63-Interactions-TRIM63/MuRF1 has been shown to interact with Titin, GMEB1 and SUMO2. | milkshake721/2.1M-wiki-STEM |
TRIM63-Regulation during skeletal muscle atrophy-During settings of skeletal muscle atrophy, the levels of Trim63/MuRF1 mRNA increase. , leading to breakdown of the sarcomere.
This was found to be due to regulation of gene expression of Trim63/MuRF1 by the FOXO (or Forkhead) family of transcription factors. ; see also ... | milkshake721/2.1M-wiki-STEM |
TRIM63-Clinical significance-Recently, it has been suggested that TRIM63/MuRF1 is associated with an autosomal-recessive form of hypertrophic cardiomyopathy (HCM). In this paper, the authors describe that individuals harboring homozygous or compound heterozygous rare variants in TRIM63/MuRF1 show a peculiar HCM phenoty... | milkshake721/2.1M-wiki-STEM |
TRIM63-Clinical significance-Upregulation of MuRF1/Trim63 mRNA is regularly used as an indicator that active skeletal muscle atrophy is occurring. | milkshake721/2.1M-wiki-STEM |
Sound-in-Syncs-Sound-in-Syncs-Sound-in-Syncs is a method of multiplexing sound and video signals into a channel designed to carry video, in which data representing the sound is inserted into the line synchronising pulse of an analogue television waveform. This is used on point-to-point links within broadcasting network... | milkshake721/2.1M-wiki-STEM |
Sound-in-Syncs-History-The technique was first developed by the BBC in the late 1960s. In 1966, The corporation's Research Department made a feasibility study of the use of pulse-code modulation (PCM) for transmitting television sound during the synchronising period of the video signal. This had several advantages: it ... | milkshake721/2.1M-wiki-STEM |
Sound-in-Syncs-History-Awards Sound-in-Syncs and its R&D engineers have won several awards, including: The Royal Television Society's Geoffrey Parr Award in 1972 A Queen's Award for Enterprise in 1974 In 1999, a Technology & Engineering Emmy Award | milkshake721/2.1M-wiki-STEM |
Sound-in-Syncs-Versions-Original mono S-i-S In the original system, as applied to 625 line analogue TV, the audio signal was sampled twice during each television line and each sample converted to 10-bit PCM. Two such samples were inserted into the next line synchronising pulse. At the destination, the audio samples wer... | milkshake721/2.1M-wiki-STEM |
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