Datasets:
habdine
/
Prot2Text-Data

Dataset card Data Studio Files
xet
Community
1
accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
16
2.75k
function
stringlengths
6
5.51k
AlphaFoldDB
stringlengths
6
10
Q8VFT4
OL734_MOUSE
Olfactory receptor 734
Mus
MEPANDTTVTEFILTGLSQTREVQLVLFVIFLSFYLFILPVNILIICTIRLDSHLSSPMYFLLANLAFLDIWYSSITAPKMLVDFFVERKIISFGGCIAQLFFLHFVGASEMFLLTVMAFDRYAAICRPLHYATIMNRRLCCILVALSWTGGFVHSIIQVALIVRLPFCGPNELDNYFCDITQVVRIACANTFLEEMVMIFSSGLISVVCFIALLMSYAFLLTMLKKHSSSGESTSRAISTCYSHITIVVLMFGPSIYIYARPFDSFSLDKVVSVFHTVIFPLLNPIIYTLRNKEVKAAMRKLVNRYIFCKEK
Olfactory receptor that acts as a receptor of Asprosin hormone at the surface of hepatocytes to promote hepatocyte glucose release . Also binds Asprosin in the arcuate nucleus of the hypothalamus, thereby stimulating appetite by promoting orexigenic AgRP neuronal activity . In testis, Asprosin-binding promotes sperm progressive motility and enhances male fertility . The activity of this receptor is mediated by G proteins which activate adenylyl cyclase, resulting in an elevation of intracellular cAMP .
Q8VFT4
Q038V7
ADDA_LACP3
ATP-dependent helicase/nuclease AddA
Lacticaseibacillus
MTQFTTSQQAAITHDGHDVLVSASAGSGKTTVLVERIIQKILKQHADITRMLIVTFTRAATAEMRTKIQTALKKALTERRHELSGEDRRHLANQIAMVNAAKISTLDAFSLQIVQTYYYVIDLDPGFRLLTDETERYMLQERVWDDLREQLYASDEAPAFEQLTANFSGDRDDSGLQDLMFELIRQAGATTDPKAYLEGLATPYAPEKWEATFSQQIWPRVKGQLLQIATSLTQASALANQLPNPIWYQQIQADLAPLQTLLETNAPTYDTVRSVLISHEFAAWSRISKGLDDADKDTKNAAKDLRDAAKKTWQNKLAPTFALAAEQIGDLLREAQPLVATLANVALKFEDALTAEKAARHVQDYSDIAHNALRILQQKDPQTGAPIADNYRASFDEVMVDEYQDISPLQEALLAAVSTTTPGDRFMVGDVKQSIYGFRLADPQLFIHKYQTFQDAPTDPAAPERIILAENFRSTKNVLAFTNLIFSQIMDPEVGDLSYDNAAALKYGALDYGDAHPAVKVLLYSKATSDEDSSDASELPGDADDNEPVDIATGQTQLVLAEIQRLINDPDAQLWDRQAQEYRRIHYRDITLLTRQTSQNSLIQTQFAAAGVPLFVADTKNFFKTTELMVMLALLKVIDNQKQDIPLVAVLRSPIVGLSADQLALIRLAAKQVPYYDAVTAFLQAEPKTPLAQRTHDMLTHFFNQLSHFRDLARENDLVTLLWAIYQDTGFLDYVGGTPGGSQRQANLQALIDRARTYEAGGFKGLFAFIHFITLMQKQDQDLAMPAQVDPDNDAVKLMTIHKSKGLEFPVVFLMQANKHFNMSDQTGTAILTKQGIGIKWLDPETRVEYELPQYQAAKAARQNQTLAEEMRLLYVALTRAQQRLYVVGATMSGNQLTSADKTVEKWAAAAEGEARVLAPQVRSGATSYLDWIGPALIRHPQARGLAETTIKPALVGDETEFTIEIDVNPQVTPTATPEKVSDDSGTMVDLSAWFKKAYPFQAATTTTGFQSVSEIKRAFDDPDTIDLVNADRFLGPKPPMRDLTAPAFLTETPSGISPAAIGTATHLLLQLVDLAKPITMASLRALRDQLTTTQVIAVDVAKHIDLTALIRFFETDLGRLLLAKPQQVHREVPFSMLLPADQVFEALADDPGEDVLIHGIIDGYVSDEQGVTLFDYKTDHNPNTAVLVDRYRGQLNLYAQALQDLQPKPVLHRYLVFLRTGTVVDLVASGAGK
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
Q038V7
Q0V7V2
P2C42_ARATH
Probable protein phosphatase 2C 42
Arabidopsis
MSGSLMNLFSLCFKPFGHVCDNSEAGSGGGGGVSGGTGGEGKDGLLWFRDLGKYCGGDFSMAVIQANQVLEDQSQVESGNFGTFVGVYDGHGGPEAARYVCDHLFNHFREISAETQGVVTRETIERAFHATEEGFASIVSELWQEIPNLATVGTCCLVGVIYQNTLFVASLGDSRVVLGKKGNCGGLSAIQLSTEHNANNEDIRWELKDLHPDDPQIVVFRHGVWRVKGIIQVSRSIGDMYMKRPEFNKEPISQKFRIAEPMKRPLMSATPTILSHPLHPNDSFLIFASDGLWEHLTNEKAVEIVHNHPRAGSAKRLIKAALHEAARKREMRYSDLRKIDKKVRRHFHDDITVIVVFLNHDLISRGHINSTQDTTVSIRSALEH
Dephosphorylates and represses plasma membrane H(+)-ATPases (PM H(+)-ATPases, e.g. AHA1 and AHA2), thus influencing negatively plant growth and fitness . Promotes the apical hook maintenance of etiolated seedlings .
Q0V7V2
P11081
TRPA_PSEPU
Tryptophan synthase alpha chain
Pseudomonas
MSRLEQRFAELKAEGRSALVTFVTAGDPGYDASLQILKGLPAAGADVIELGMPFTDPMADGVAIQLATLRALEAGQTLAKTLQMVREFRVDNHTTPIVLMGYYNPIHRFGVEKFVAEAKQAGVDGLIIVDLPPEHDAELATPAQAAGIDFIRLTTPTTDDARLPRVLERSSGFVYYVSVAGVTGAGSATTEHVTEAIARLRRHTDLPISVGFGIRTPEQAANIARLADGVVVGSALVDKIAQATSADQAVNDVLSLCSALAEGVRGARR
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
P11081
Q9LFH3
LOG4_ARATH
Protein LONELY GUY 4
Arabidopsis
MEVNNETMQKSKFGRICVFCGSSQGKKSSYQDAAVDLGNELVLRNIDLVYGGGSIGLMGLVSQAVHDGGRHVIGVIPKTLMPRELTGETVGEVRAVADMHQRKAEMARHSDAFIALPGGYGTLEELLEVITWAQLGIHDKPVGLLNVDGYYNSLLSFIDKAVEEGFISTNARQIIISAPTAKELVKKLEEYSPCHESVATKLCWEIERIDYSSED
Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.
Q9LFH3
Q68XR7
RL9_RICTY
50S ribosomal protein L9
typhus group
MEIILIKPVRKLGKIGDILKVANGFGRNYLLPQKLAIRATKSNKELIVKQKHEFEAKDKQIRAEVEKINTLIKDQQLVFIRQTSDDCKLFGSVTNKDIADKLSKNISYNISHSNVILDKQIKSTGIYTVEIRLHAELTAIVTVIVARSDSEAQDYLREQKTENSADLAESE
Binds to the 23S rRNA.
Q68XR7
Q67YU0
CKX5_ARATH
Cytokinin oxidase 5
Arabidopsis
MNREMTSSFLLLTFAICKLIIAVGLNVGPSELLRIGAIDVDGHFTVHPSDLASVSSDFGMLKSPEEPLAVLHPSSAEDVARLVRTAYGSATAFPVSARGHGHSINGQAAAGRNGVVVEMNHGVTGTPKPLVRPDEMYVDVWGGELWVDVLKKTLEHGLAPKSWTDYLYLTVGGTLSNAGISGQAFHHGPQISNVLELDVVTGKGEVMRCSEEENTRLFHGVLGGLGQFGIITRARISLEPAPQRVRWIRVLYSSFKVFTEDQEYLISMHGQLKFDYVEGFVIVDEGLVNNWRSSFFSPRNPVKISSVSSNGSVLYCLEITKNYHDSDSEIVDQEVEILMKKLNFIPTSVFTTDLQYVDFLDRVHKAELKLRSKNLWEVPHPWLNLFVPKSRISDFDKGVFKGILGNKTSGPILIYPMNKDKWDERSSAVTPDEEVFYLVALLRSALTDGEETQKLEYLKDQNRRILEFCEQAKINVKQYLPHHATQEEWVAHFGDKWDRFRSLKAEFDPRHILATGQRIFQNPSLSLFPPSSSSSSAASW
Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group.
Q67YU0
Q14JC3
RS7_FRAT1
30S ribosomal protein S7
Francisella
MSRRNRAPKRDILPDPKYKSQVVAKFVNHIMLSGKKSIAEKIVYGAFDKIKAKDASANEVEVFEKALESVSPMVEVKSRRVGGATYQVPVEVRPERRQTLGMRWIIDAARKRKENTMGDRVAAEILEAVEGRGAAVKKREDTHKMAEANKAFAHFRW
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
Q14JC3
Q60879
OLF3_MOUSE
Olfactory receptor 136-14
Mus
MRLKNHSSVSEFLLLGFPIRPEQGGIFFSLFLAMYLITVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTVPKMLTKVQNQPIPITYEECVSQTYFFIFFADLDSFLITSMAYDRYMAICHPLHYITIMSQSRCAMLVAVSWVIASACALLHSLLLDQLSFCADHTVPHFFCDLGALLKLSCSDTSLNQLVIFTAGLAAIMLPFLCILISYGRIGFTILQVPTTKGICKALSTCGSHLSVVALYYGSIIGLYFLPPSNSKINNNIVASVMYTVVTPMLNPFIYSLRNKDMKGALKKLLSKKTEFSK
Odorant receptor.
Q60879
A5E625
YAE1_LODEL
Protein YAE1
Lodderomyces
MQPSYKDLHCACQSNSQTNQSSVYSMSDDIWEDDDEDEEQEEYDRGDNSNDYNKDGVGSRQQNKQTQSLAMNEIARRHRKQGYVDGLAKHQEENLQKGFDFAYSIGADLGIKVGRLLARACIADGANNDLKDKSGGSGNDLGSLKECMNALNISKVLDLKYFDDHLNLKDGKHGLIEEWQNKSN
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.
A5E625
Q3T905
CBPB_HELZE
Carboxypeptidase B
Helicoverpa
MKFLLVLALCAVVYAKHEAYIGWKSYYVGVATDAQAKALEPLIQKYELDFLSHPTKSREGVVLVKPQHQAGFVQDIEAGGITYRIHADDVKRQLEFDDQLIEMQRMSSFTRTAGRQLPYDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFIDGGIHAREWISPPSVTWAIHKLVEDVTENDLLEKFDWILLPVVNPDGYKYTFTNERFWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDILHEHLARMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPYTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWEGIVVGARRAGDLFRK
Metalloprotease which cleaves a single amino acid from the C-terminal end of polypeptide chains. Shows a strong preference for peptides with a terminal lysine residue.
Q3T905
P48651
PTSS1_HUMAN
Serine-exchange enzyme I
Homo
MASCVGSRTLSKDDVNYKMHFRMINEQQVEDITIDFFYRPHTITLLSFTIVSLMYFAFTRDDSVPEDNIWRGILSVIFFFLIISVLAFPNGPFTRPHPALWRMVFGLSVLYFLFLVFLLFLNFEQVKSLMYWLDPNLRYATREADVMEYAVNCHVITWERIISHFDIFAFGHFWGWAMKALLIRSYGLCWTISITWELTELFFMHLLPNFAECWWDQVILDILLCNGGGIWLGMVVCRFLEMRTYHWASFKDIHTTTGKIKRAVLQFTPASWTYVRWFDPKSSFQRVAGVYLFMIIWQLTELNTFFLKHIFVFQASHPLSWGRILFIGGITAPTVRQYYAYLTDTQCKRVGTQCWVFGVIGFLEAIVCIKFGQDLFSKTQILYVVLWLLCVAFTTFLCLYGMIWYAEHYGHREKTYSECEDGTYSPEISWHHRKGTKGSEDSPPKHAGNNESHSSRRRNRHSKSKVTNGVGKK
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine . Catalyzes mainly the conversion of phosphatidylcholine . Also converts, in vitro and to a lesser extent, phosphatidylethanolamine .
P48651
A1DH62
NAGS_NEOFI
N-acetylglutamate synthase
Aspergillus subgen. Fumigati
MSPHTGWPRTVNSSLLKKHRSSLCTCQHTSSFLPRSFSTTADRHVQQSADFSSTSRSYDRLGRRAKEKLLDREFFLSLLSSASTKREAKSYLARLKAQYPKSPDENKPEPEKLATAPTLPSGVNLGSFYGASRSVYESPVFRQGPSPTAPPSLEPVERLHLALVRLSTPQSLDDNIIDGVAKTLSQLNRLGLTCCVVVDPGTEGVASTLRQVAIEQADRLAVAIQKQPDSKSLRLDSVFSIDASRPGLPQVSSRKALLNPLRHGHTVILTPIAYTEDVPRAIIVPANDAVLALTKELAGLASTPDPDEDPMVTAERIGRLQKEVSLDRVILLDSLGGIPAFNRRQTSHVFINMEQEYDDIENELLQAREMVPATETSLLKAGPSSIADNNPVSKFVNAEVVPVPSGPTQELKTAAPQRSAIEGHLENLRVAQKALTMLPAASSGIITSPFEVASSAQPSPTSEFSAVGTRRQRNPLIHNLLTDKPLLSSSLPMSRRGPTNNGQGTVYPVTSHTTFVKRGMPLTMLPNPWTEPWTPQSRPRLKLDDPSIDLPRLVHLIEDSFDRKLDVQDYLNRVNDRLAGLIIAGEYEGGAILTWELPPGVEDDGSEASNARMVPYLDKFAVLKRSQGAGGVADIVFNAMVRSCFPNGVCWRSRKNNPVNKWYFERSLGTWKLSDTNWTMFWTTPSLVEDSQKFRDYEAVCRSTQPSWADDTGVVD
N-acetylglutamate synthase involved in arginine biosynthesis.
A1DH62
A6GVQ2
SYM_FLAPJ
Methionyl-tRNA synthetase
Flavobacterium
MIQNPKRYTITAALPYTNGPIHIGHLAGVYMPSDIYSRYLRLQGKDVAFMCGSDEHGVAISMKAKKEGITPQEVIDKYDGIIRKSFVDFGISFDNYSRTSAKIHHDTASEFFKKLYDKGDFIEEVTEQLYDAKADQFLADRFVVGTCPKCGNEEAYGDQCEKCGSTLNATDLINPKSTITGETPIMKSTKHWFLPLDRYSDFLTKWILEGHKSDWKPNVYGQVKSWIDGGLEPRAVTRDLDWGIDVPVAGAEGKKLYVWFDAPIGYISATKEWAAREGKDWELYWKNEDTKLVHFIGKDNIVFHCIIFPAMLKAEGSYILPDNVPANEFLNLEGNKLSTSKNWAVWLHEYLEDFPNQQDVLRYALTANAPESKDNDFTWKDFQARNNNELAAIFGNFINRVVVLTNKYYEGVVPTPNKFSEVDEATLTELKAYPAVISSSIERYRFREALGELMNVARLGNKYLADEEPWKMVKTDPERVKTQMYVALQIATALRVLCEPFLPFTAEKLNKMLKIDAKLSWNDVTTNSDLILAGHKIGEGEILFAQIEDEQIQKQIDKLEATKTANIAENKKAEPQKELIQYDDFAKMDLRVGTIIEAEKMPKANKLLVLKVDTGIDVRTIVSGIAESFSPEEIIGKQVTVLVNLAPRALRGIESQGMILMTNLPDGKLAFVNPDVAGVGNGEGIN
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
A6GVQ2
B7NL16
LPXH_ECO7I
UDP-2,3-diacylglucosamine diphosphatase
Escherichia
MATLFIADLHLCAEEPAITAGFLRFLAREARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDIGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
B7NL16
P42890
COL_RABIT
Colipase
Oryctolagus
MEKVLVLLLVALSVAYAAPGPRGIVINLEEGELCLNSAQCKSGCCHHSSALSLARCAPKASENSECSPQTIYGVYYKCPCERGLTCEGDKSIVGSITNTNFGVCLDV
Enterostatin has a biological activity as a satiety signal.
P42890
Q97A63
CBID_THEVO
Cobalt-precorrin-6A synthase
Thermoplasma
MMYASDGSGVNPFQQYGITTGLTAAAAAKACTLTVLKGVQNRVVVPTPIGIRIEVKVVESVRIDESSGYASAEKFSGDNPDQLNGITIRCHCKVVKKQENGRSKITISGNAGIGVVEKDGLGIRPGEKAISQGARKMIEDAVREAAGGYDVELSISVPNGEEFAKLTMNEKVGVFGGISVLGTTGIEEPVSTEEYELHLKYIVAAGRCVSKIIVLCPGNTALKFAKKYFALPDKAFVLIGDKVGAAVSASIESAYDHVVIFGLPGKLVKIAAGIYNTHSKVADGRMETLAAVAAMYGISKGAVKRIMESSNTGEAISIIEQEGIVAEVLNTIASRISNRLKADFSRSVGFSVVIIDHDGKIIGSHLDGHIKEVLKYGK
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
Q97A63
C1F127
RSMA_ACIC5
S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase
Acidobacterium
MRGGWGRFPPKSREVAAISGKHKPKLGQNFLVSEAACRSIVEALGNLGARTVVEIGPGKGAITELLANRAERLIAIELDRELAPRLRERFARRETVTVIEDDVLRVDLSALARPGEKLLVVGNLPYYMTSEILLHLIRHEAAIERAVVMVQREVADRVAAGPGSRDYGLLSVTAQLHARVEKLLTLPPGAFSPPPEVYSTVLRWTMHSRTDELGVDPTRFTGFLRSCFAQKRKTLGNNLRAAKYEPAAIAGAMQSAGVAAGVRAEELSLEALAALWRTLEDRS
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
C1F127
A1K1R8
ATPF_AZOSB
F-type ATPase subunit b
Azoarcus
MNLNATLIAQLVVFFILAWFTMKFVWPPIVKALDERAKKIADGLAAADKAKADLALAEKKVVEELRKARESAGDVRASAEKQASQLVDEARAEASRIIAQAREAAEAEAGAAAQRAKEALRDQVAHLAVAGAEKILRREINAQVHAELLANLKQELQ
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
A1K1R8
Q5F5T0
RL2_NEIG1
50S ribosomal protein L2
Neisseria
MAIVKMKPTSAGRRGMVRVVTEGLHKGAPYAPLLEKKNSTAGRNNNGHITTRHKGGGHKHHYRVVDFKRNKDGISAKVERIEYDPNRTAFIALLCYADGERRYIIAPRGIQAGVVLVSGAEAAIKVGNTLPIRNIPVGTTIHCIEMKPGKGAQIARSAGASAVLLAKEGAYAQVRLRSGEVRKINVDCRATIGEVGNEEQSLKKIGKAGANRWRGIRPTVRGVVMNPVDHPHGGGEGRTGEAREPVSPWGTPAKGYRTRNNKRTDNMIVRRRYSNKG
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
Q5F5T0
Q6PR31
ECTC_VIRPA
N-acetyldiaminobutyrate dehydratase
Virgibacillus
MIVKSLDDIIGTDDETSSDNWTSRRFIMKKDNVGFSLNDTLIKAGTTNFFWYKNHIEAVYCIEGEGEIEKLETGEIYKLKAGTMYLLNEHDKHELRAKTQMRMVCVFNPPLVGTETHTEEGYYPLLTE
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
Q6PR31
A6LLN8
RS13_THEM4
30S ribosomal protein S13
Thermosipho
MARIVGVEIPNDKKVEIALTYIYGIGKTRAKQICEATNIDPNKRVRELGDEEISKIATFIQQNYKVEGELRTEVMQNIKRLIDIGCYRGLRHKLGLPVRGQKTKSNARTRKGPRPSRIKKKK
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
A6LLN8
B4S5M3
RS19_PROA2
30S ribosomal protein S19
Prosthecochloris
MPRSLKKGPFIEGKLEKRILDMNSREEKKVVKTWARSSMISPDFVGHTVAVHNGKTHVPVYISENMVGHKLGEFAPTRTYRGHAGGKAEKGGSAPKRK
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
B4S5M3
C7GPS8
ASA1_YEAS2
ASTRA-associated protein 1
Saccharomyces
MRGFSNEIILKRTLTLSDFTLRYHKRGITALQVIKAPSVSNVPVLLSGDNYGYFVMWDLVTKRPITHMEIEGNSHIIAFWWVETTNVLYILSKDSMLRIFELDSSTQRSIDLVRKLSQANKTDHLQWTKIYEMPINTLNFANFIIEAEVKPTKDNKSYRLVCCHTDDSETIDIYQIIEDSTFKLKRPFNNINFPRFLKQQNFLGISKDSKFGIIMRFAKLNDVIFLGYENGFVVGFKITFDEGLQRDIAELVHVSNDHYPNPILDMCVSGDELYSCSTDDFITKYKIPVNLQLETKYLRDDALLIKCPSSLRVSEPSKVHLPLKNIGHIDKVKDDYLVVSSWSGMTIVYNMRTSEVEQTFVKSKNNLVVSDSSMGDLTNGSGSNTESSSKSHNYKVGAMTCLESFDVQSDGLRLGQLRRIKALAKCNWCLIGYEDGTIKLNKI
Component of the ASTRA complex involved in chromatin remodeling.
C7GPS8
Q4QJK4
RPOZ_HAEI8
Transcriptase subunit omega
Haemophilus
MARVTVQDAVEKIGNRFDLILTAARRARQLQLNQSAPLVPEDNDKPTVIALREIEKGLINQDIMDAQEFQKMAKVQETEEAAVALITE
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
Q4QJK4
A2C9T2
COAD_PROM3
Pantetheine-phosphate adenylyltransferase
Prochlorococcus
MRALYPGSFDPLTLGHLDLIERGCALFGEVVVAVLSNPAKTPAFTLQQRFNQIHVATAHCKGVSVISFDGLTVRCARHNQVDLILRGLRAMSDFEYELQIAHTNRSLAPDFETIFLATAAHHSFLSSSMVKEVARFGGNIDHMVPEVVAQDLHRLFN
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
A2C9T2
P24202
MRR_ECOLI
Mrr restriction system protein
Escherichia
MTVPTYDKFIEPVLRYLATKPEGAAARDVHEAAADALGLDDSQRAKVITSGQLVYKNRAGWAHDRLKRAGLSQSLSRGKWCLTPAGFDWVASHPQPMTEQETNHLAFAFVNVKLKSRPDAVDLDPKADSPDHEELAKSSPDDRLDQALKELRDAVADEVLENLLQVSPSRFEVIVLDVLHRLGYGGHRDDLQRVGGTGDGGIDGVISLDKLGLEKVYVQAKRWQNTVGRPELQAFYGALAGQKAKRGVFITTSGFTSQARDFAQSVEGMVLVDGERLVHLMIENEVGVSSRLLKVPKLDMDYFE
Involved in the acceptance of foreign DNA which is modified. Restricts both adenine- and cytosine-methylated DNA.
P24202
P39802
CHEW_BACSU
Coupling protein CheW
Bacillus
MTAEIKTGEKMIVFMVNGKEYAISVTQVKSIEKWQKPTRVPGVEPYICGVINLRGVVTPVIDLRKRLNLPEYEITDETRIIIIAYRDIEVGWIVDEANDVITVHESEIESAPEGVQKDTDVSIEQIVKQENRLLNIIDANAVLDKESSQSAVPDQA
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase CheA; they are both necessary for efficient chemotaxis.
P39802
Q6FRT5
FLR2_CANGA
Flucytosine exporter FLR2
Nakaseomyces/Candida clade
MYIGAFQDTLFVDMLEYFGWVTVGKEYLDIYRPNGVPVAPNAVAASISGKEEMKQDNQTSTDSMSTSTQQETDASNEDIERAMDTDNGLDKAMSGGQGVFGTEEDDSSTKDASKPEEADPFLVEFLGEDDPRKPWNWSFSKKTFVIVQLMVLTCINYMGSSIYTPGQEQIQHEFHVGHVVGTLNLSMYVLGYAIGPIIFSPLSEVSSIGRMPLYLWTFILFTILQVACALVRNIAGLVILRFITGILCSPVLATGGASVGDVCFPRYVPRFLGAWAVGAVAAPVMAPILGAAMVVAKDWRWIFWLMLFMCGATLLSIIFFFPETSHECILHRRAKRLRKLTGDDRYYTKKEKQEEALPVSVFIKNTLWRPIKMIALEPIILAFDVYIALCYGAFYLFFEAFPIVFAGIYHFTLVEVGLAFLGFCVGCVFAYTALIIFQEKVIRKKFLEGKFRPELFLILAMCLGWCLPFSLFFFGWTARIHWILPIIAELFFVLSVFNLFQATFSYLAVCYPEYVASVFAGNGLCRGAFAAAFPLFGKAMYDRLSTKKYPVAWGSTLIGFITVVLSLIPFVLYKYGPALRARSRFSPDS
Multidrug transporter that confers resistance to 5-flucytosine (5-FC) and clotrimazole . Further confers azole drug resistance . Plays direct roles in extrusion of 5-flucytosine and clotrimazole .
Q6FRT5
Q7V3V8
UREG_PROMM
Urease accessory protein UreG
Prochlorococcus
MSSKLRLGVAGPVGSGKTALVEAMCRRLRDQLQLAVVTNDIYTQEDAEFLTRVGALEPERIRGVETGGCPHTAIREDCSINRAAVEDLERNFPDLDVVLVESGGDNLAASFSPELVDLCIYVIDVAAGDKIPRKGGPGITRSDLLVINKIDLAVHVGADLEVMKRDTTRMRGERPWCFTNLRSGDGLESVLHFLLQQLPNRP
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
Q7V3V8
O42945
DHX15_SCHPO
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43
Schizosaccharomyces
MEPAQKKLRQESKNPYLAHLNNGDDSEEVVSSKGLTRRATTVAQAAKAEEGPNNFFNDKPFSQNYFKILETRRELPVYQQREEFLKIYHENQIIVFVGETGSGKTTQIPQFVLYDELPHLTNTQIACTQPRRVAAMSVAKRVADEMDVDLGEEVGYNIRFEDCSGPNTLLKYMTDGMLLREAMTDHMLSRYSCIILDEAHERTLATDILMGLMKRLATRRPDLKIIVMSATLDAKKFQKYFFDAPLLAVPGRTYPVEIYYTQEPERDYLEAALRTVLQIHVEEGPGDILVFLTGEEEIEDACRKITLEADDLVREGAAGPLKVYPLYGSLPPNQQQRIFEPTPEDTKSGYGRKVVISTNIAETSLTIDGIVYVVDPGFSKQKIYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFRKELIEQTYPEILRSNLSSTVLELKKLGIDDLVHFDYMDPPAPETMMRALEELNYLNCLDDNGDLTPLGRKASEFPLDPNLAVMLIRSPEFYCSNEVLSLTALLSVPNVFVRPNSARKLADEMRQQFTHPDGDHLTLLNVYHAYKSGEGTADWCWNHFLSHRALISADNVRKQLRRTMERQEVELISTPFDDKNYYVNIRRALVSGFFMQVAKKSANGKNYVTMKDNQVVSLHPSCGLSVTPEWVVYNEFVLTTKSFIRNVTAIRPEWLIELAPNYYDLDDFDNNKEVKSALQKVYQMAARSKKNARR
Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.
O42945
Q6YXM0
PETL_PHYPA
Cytochrome b6-f complex subunit VI
Physcomitrium
MLTIISYFGFLFGALTLALILFIGLNKIQLI
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
Q6YXM0
Q97E91
SP5G_CLOAB
Putative septation protein SpoVG
Clostridium
MQITDVRIRKITSEGKMKAIVSVTFDNEFVVHDIKVIEGQNGLFIAMPSRKTPDGEFKDIAHPINTATREKIQSAILAEYEKVKNEEETKTETEE
Could be involved in septation.
Q97E91
Q8GQN9
BCLA_THAAR
Benzoyl-CoA synthetase
Thauera
MYTLSVADHSNTPPAIKIPERYNAADDLIGRNLLAGRGGKTVYIDDAGSYTYDELALRVNRCGSALRTTLGLQPKDRVLVCVLDGIDFPTTFLGAIKGGVVPIAINTLLTESDYEYMLTDSAARVAVVSQELLPLFAPMLGKVPTLEHLVVAGGAGEDSLAALLATGSEQFEAAPTRPDDHCFWLYSSGSTGAPKGTVHIHSDLIHTAELYARPILGIREGDVVFSAAKLFFAYGLGNGLIFPLAVGATAVLMAERPTPAAVFERLRRHQPDIFYGVPTLYASMLANPDCPKEGELRLRACTSAGEALPEDVGRRWQARFGVDILDGIGSTEMLHIFLSNRAGDVHYGTSGKPVPGYRLRLIDEDGAEITTAGVAGELQISGPSSAVMYWNNPEKTAATFMGEWTRSGDKYLVNDEGYYVYAGRSDDMLKVSGIYVSPIEVESALIAHEAVLEAAVVGWEDEDHLIKPKAFIVLKPGYGAGEALRTDLKAHVKNLLAPYKYPRWIEFVDDLPKTATGKIQRFKLRSA
Catalyzes the ligation of benzoate and CoA to form benzoyl-CoA at the expense of ATP. The enzyme also ligates 2-aminobenzoate and CoA. The enzyme shows activity toward a number of benzoate derivatives.
Q8GQN9
Q6N075
MFSD5_HUMAN
Molybdate transporter 2 homolog
Homo
MLVTAYLAFVGLLASCLGLELSRCRAKPPGRACSNPSFLRFQLDFYQVYFLALAADWLQAPYLYKLYQHYYFLEGQIAILYVCGLASTVLFGLVASSLVDWLGRKNSCVLFSLTYSLCCLTKLSQDYFVLLVGRALGGLSTALLFSAFEAWYIHEHVERHDFPAEWIPATFARAAFWNHVLAVVAGVAAEAVASWIGLGPVAPFVAAIPLLALAGALALRNWGENYDRQRAFSRTCAGGLRCLLSDRRVLLLGTIQALFESVIFIFVFLWTPVLDPHGAPLGIIFSSFMAASLLGSSLYRIATSKRYHLQPMHLLSLAVLIVVFSLFMLTFSTSPGQESPVESFIAFLLIELACGLYFPSMSFLRRKVIPETEQAGVLNWFRVPLHSLACLGLLVLHDSDRKTGTRNMFSICSAVMVMALLAVVGLFTVVRHDAELRVPSPTEEPYAPEL
Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
Q6N075
Q8RU95
4CLL6_ORYSJ
4-coumarate--CoA ligase-like 6
Oryza sativa
MSKRSPPPQPAHIPMAEQRWRPPYPYASSAAGGGGVDRRSRSGFCAATRTFHSLRSVGPLPPEELPLTVAAYAFSLLSSAPPLVVAGRGPALVDAATGIAVSYPAFVARVRFLAGGLWCSLGLRPGDVALVVSPSCLDVAVLYFALMSIGVVVSPANPASTADEYAHQVRLSRPAIAFVAPEVAARLPRHVSRVVIGSEVFDRLASASAAGGWAAPPAVAMKQPSTAALLYSSGTTGRVKAVAITHRNLIAQISAYNAIRETVAREAATDAGKGKPPPPSPSPPAAVTLFPLPLFHVMGFGLLTRTISSGETAVVMRRFDLAAAARAVERYRVTKLSAAPPVVVALTKSDEARRRDLSSLVAIVVGGAPLGREVSQRFATVFPSVQIVQSYGLTESTGPVATMAGPEESAAYGSVGRLAPRVQAKIVDTATGEVLGPGRRGELWIRGPVVMKGYVGDPEATAATITPDGWLKTGDLCYFNEDGYLYVVDRLKELIKYKGYQVPPAELEHILQSRPEIADAAVVPYPDEEAGQLPMAFVVRQPGAYLTEQQVMNCVAKHVAPYKKVRRVAFVNAIPKSPAGKILRRELVLQAMASTSRL
Carboxylate--CoA ligase that may use 4-coumarate as substrate. Follows a two-step reaction mechanism, wherein the carboxylate substrate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield the final CoA thioester.
Q8RU95
A9M383
IHFA_NEIM0
Integration host factor subunit alpha
Neisseria
MTLTKAELADILVDKVSNVTKNDAKEIVELFFEEIRSTLASGEEIKISGFGNFQLRDKPQRPGRNPKTGEEVPITARRVVTFHASQKLKSMVEHYYDKQR
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
A9M383
Q8EFV9
FABA_SHEON
Trans-2-decenoyl-[acyl-carrier-protein] isomerase
Shewanella
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMIDRIITINDNGGEFGKGEIVAELDIKPELWFFDCHFITDPVMPGCLGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDLKVGVFSDTSTF
Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
Q8EFV9
Q18JW6
G1PDH_HALWD
sn-glycerol-1-phosphate dehydrogenase
Haloquadratum
MLKKTTWIKLPRNVLVGHDVIGDLAAAIEELYLDGRPLIVTSPTPDQLIGNRVRSQFADPQTVSVDHASFDAVEAVIDTAKATDAGYLIGLGGGKPIDTAKMASDRLGCGFVSVPTAASHDGIVSGRSSIPEGDTRHSVAADPPLAVVADTAVLAEAPWELTTAGCADIISNYTAVKDWQLAHRLQDVEYSEYAGALSQMTAEMLVDNSDAIKQGFEESAWLVAKALVSSGVAMSIAGSSRPASGAEHLISHQLDRLVPDAALHGHQVGVASIVTAYLHTGENGEWEDIRAALADVGAPTTATELGIDEEIFIQAITSAHAIRDRHTILGNGVSEAAAREAAVFTDVC
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
Q18JW6
O66426
YZ38_AQUAE
Probable protein adenylyltransferase aq_aa38
Aquifex
MTYQNGVEVLLEEFLDYLTKEETICSLEIEKLKVSIDELEKETDEPRVLQGINYFRTAKEVYQLSRKAYETKEEVVSEALILWIYENLWKGFNVPKGYRKSDMVIFGAKFSPPPPYVVPNLIRTIVNWLRNEKTIDVVKKSIIFHTLFEVIHPFPDGNGRVGRILLNAILVENGLLNVAFRNREKYISALREAEEGAIVVVEKLSRGRKIDYSSITETVEYYGNLNVFDELIRTEMMHSLKVYSNIKQVFLTPEEAAKLLGLKNKDYVRVLIHRGKLKAVKEEGKWKIPLSEVVKNFEHKLKGEEFKLANNLFKGKLSPS
Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
O66426
Q8K0C4
CP51A_MOUSE
Sterol 14-alpha demethylase
Mus
MVLLGLLQSGGWVLGQAMEQVTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPHIYSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVYGRLTTPVFGKGVAYDVPNAIFLEQKKIIKSGLNIAHFKQYVPIIEKEAKEYFQSWGESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFTHAAWLLPAWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPAEDILQTLLDSTYKDGRPLTDEEISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGEDLPPLTYDQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWAERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYEFDLINGYFPTVNYTTMIHTPENPVIRYKRRSK
A cytochrome P450 monooxygenase involved in sterol biosynthesis. Catalyzes 14-alpha demethylation of lanosterol and 24,25-dihydrolanosterol likely through sequential oxidative conversion of 14-alpha methyl group to hydroxymethyl, then to carboxylaldehyde, followed by the formation of the delta 14,15 double bond in the sterol core and concomitant release of formic acid. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
Q8K0C4
Q2K9C7
AZOR1_RHIEC
FMN-dependent NADH-azoreductase 1
Rhizobium
MSSILLLTSSPRAESLSTPIAADLAEKLKNQKPGSVVVRRDLAATPLPHIDDLFTGAIRKPAEARTAEEIAAVKTSDELVAELFAADTIVISTGLINFNIYSSLKTWIDNVARAGVTFKYTESGPVGLVTGKKVYVVLASGGVYSQGPAAPLNHAVPYLKSVLGFLGITDIETIYVEGLAFGPEAAEKAIGAAKSRVEEIALAA
Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
Q2K9C7
Q75WV3
TPP1_ORYSJ
Trehalose 6-phosphate phosphatase
Oryza sativa
MDLSNSSPVITDPVAISQQLLGGLPSNLMQFSVMPGGYSSSGMNVGVSRLKIEEVLVNGLLDAMKSSSPRRRLNVAFGEDNSSEEEDPAYSAWMAKCPSALASFKQIVASAQGKKIAVFLDYDGTLSPIVDDPDKAVMSPVMRAAVRNVAKYFPTAIVSGRSRNKVFEFVKLKELYYAGSHGMDIMAPSANHEHSAEKSKQANLFQPAHDFLPMIDEVTKSLLQVVSGIEGATVENNKFCVSVHYRNVAEKDWKLVARLVNEVLEAFPRLKVTNGRMVLEVRPVIDWDKGKAVEFLLQSLGLNDSENVIPIYIGDDRTDEDAFKVLRQRNCGYGILVSQVPKETEAFYSLRDPSEVMEFLNFLVRWKKHSV
Removes the phosphate from trehalose 6-phosphate to produce free trehalose. Trehalose accumulation in plant improves abiotic stress tolerance.
Q75WV3
Q5F5X9
RNH2_NEIG1
Ribonuclease HII
Neisseria
MHILTAGVDEAGRGPLVGSVFAAAVILPETFDLPGLTDSKKLSEKKRDALAEMIKEQAVAWHVAASTPEEIASLNILHATMLAMKRAVYGLAARPEKIFIDGNRIPEHLGIPAEAVVKGDSKIIEISAASVLAKTARDAEMYALAQRRPQYGFDKHKGYGTKQHLEALKQYGVLPEHRRDFAPVRNLLAQQALF
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Q5F5X9
Q7FZF1
CNBL5_ARATH
SOS3-like calcium-binding protein 4
Arabidopsis
MGCVCSKQLEGRRQEDISLLASQTFFSEAEVEVLHGLFIKLTSCLSNDNLLTKEKFQFILIKNTKKRSLSAERIFGLFDMRNDGAIDFGEFVHTLNIFHPNSSPRDKAIFAFRLYDTRETGFIEPEEVKEMIIDVLEESELMLSESIIDSIVSKTFEEADWKKDGIIDLEEWENFVATYPLTLKNMTIPFLKDIPRIFPTFLR
Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. May function as a positive regulator of salt or drought responses.
Q7FZF1
O87877
BCRD_THAAR
3-hydroxybenzoyl-CoA reductase subunit delta
Thauera
MTITAGIDIGTGAVKTVLFRVEGDKTEWLAKRNDRIRQRDPFKLAEEAYNGLLEEAGLKASDVDYVATTGEGESLAFHTGHFYSMTTHARGAVYLNPEARAVLDIGALHGRAIRNDERGKVETYKMTSQCASGSGQFLENIARYLGIAQDEIGSLSTQADNPEVVSSICAVLAETDVINMVSRGISAPNILKGIHISMAGRLAKLLKSVGARDGVVLCTGGLALDEGLLKTLNESIQEQKMAVVAYNHPDSPYAGAIGAALWGAFRHEKLARLGQQQVAEAA
Catalyzes the anaerobic reduction of benzoyl-CoA and 3-hydroxybenzoyl-CoA to form cyclohexa-1,5-diene-1-carbonyl-CoA and 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA, respectively. The enzyme also reduces other benzoyl-CoA analogs with small substituents at the aromatic ring.
O87877
A1B028
RL4_PARDP
50S ribosomal protein L4
Paracoccus
MKLDVITLDAGKAGDIDLSDDIFGLEPRADLLHRVVRWQRAKAQAGTHSVLGKSDVSYSTKKIYRQKGTGGARHGSRKAPIFRHGGVYKGPTPRSHAFDLPKKVRALGLKHALSAKAAAGELVVVDSLNIAEAKTAAVAKAVKENGWKRVLVIDGAEVNENFARAARNLEGVDVLPSMGANVYDILRRDTLVLTRAGVEALEARLK
Forms part of the polypeptide exit tunnel.
A1B028
B1G889
OIAK_PARG4
3-oxo-isoapionate kinase
Paraburkholderia
MNGTEPAEPTNGTNATAWPAGLLLAYYGDDFTGSTDAMEAMQAAGVPTVLCLQKPTPELLARFPEVRCVGMAGSSRGRSSAWMDDELPDVLASLAALGAPILQYKVCSTFDSSPEVGSIGRAIDIGVRHMPGNWSPMVIGAPRLKRYQMFGNLFAAVDGVGYRLDRHPTMSRHPVTPMNEADLRLHLARQTARRIELIDMLELRGADVATRVRALCAPDMPVVLIDVLDEETLAEAGRLVWEQRGEGIFTASSSGLQYALAAHWRARGLLPPTPSLPAADPVQAIAAVSGSCSPVTAAQIGWARAHGFHTERLDLPRALDSRDGAAEIERVVTAATQALTRGISVIVHSAEGPDDPAVTGFDAIASAAGFARHDAARKVGRALAEVMRRLLDSVELTRVVVAGGDSSGEVASVLGIDALSVMAGLVPGAPLCRAWSAEPRRDGLQIVLKGGQIGDATFFGMVREGRLAGA
Involved in catabolism of D-apiose. Catalyzes the phosphorylation of 3-oxo-isoapionate to 3-oxo-isoapionate 4-phosphate.
B1G889
Q3HVN1
AGUB_SOLTU
N-carbamoylputrescine amidase
Solanum
MAEKNRLVTVAALQFACTDDVSTNVATAERLVRAAHQKGANIILIQELFEGYYFCQAQKEEFFHRAKPYLGHPTIVRMQNLAKELGVVIPVSFFEEANNAHYNSVAIIDADGTDLGLYRKSHIPDGPGYQEKFYFNPGDTGFKVFQTKYAKIGVAICWDQWFPEAARAMALQGAEVLFYPTAIGSEPQDDGLDSRDHWRRVMQGHAGANVVPLVASNRIGKEIIETEHGNSEITFYGYSFIAGPTGELVAAAGDKEEAVLVAQFDLDKIKSKRHGWGVYRDRRPDLYKVLLTLDGSNPVK
Involved in polyamine biosynthesis.
Q3HVN1
B7HII4
PDXT_BACC4
Pyridoxal 5'-phosphate synthase glutaminase subunit
Bacillus cereus group
MVKIGVLGLQGAVREHVKSVEASGAEAVVVKRIEQLEEIDGLILPGGESTTMRRLIDKYAFMEPLRTFAKSGKPMFGTCAGMILLAKTLIGYEEAHIGAMDITVERNAFGRQKDSFEAALSIEGVGEDFVGVFIRAPYVVEVADNVEVLSKHGNRMVAVRQDQFLAASFHPELTDDHRVTAYFVEMVKEAKMKKVV
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
B7HII4
Q5E9Q4
NECP2_BOVIN
NECAP endocytosis-associated protein 2
Bos
MEEAEYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQVAYIKLEDRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQNPDQGPKLDLSFKEGQTIKLNIASMKKKDGAAGTPRARPTSTGGLSLLPPPPGAKTAALAPLSGEHLSVGGSVVQPAVSPSSGGATVSWPQPKPATTATADIWGDFTKSTGSTSSQTQPGAGWVQF
Involved in endocytosis.
Q5E9Q4
Q6DGV1
CELF4_DANRE
RNA-binding protein BRUNOL-4
Danio
MATLTNGQVDAAVHGGAASTNGLVNGISHTHSPASCATIPMKDHDAIKLFIGQIPRNLDEKDLRPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCARESALKAQTALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQCEDDVRRLFESFGSIEECTILRGPDGNSKGCAFVKYSTHAEAQAAISALHGSQTMPGASSSLVVKFADTDKERTIRRMQQMAGQMGIFNPMALQFGAYGAYAQVQQQAALMASVGQGGYLSPMAAFAAAQMQHMATINGLPGAPMTPTSGGSTPPGITAPTVTSIPSPISVNGFTGLPPPQANGQAPAEAMFTNGIHPYPVLQEVVFREDSEKGGLGVAQRSCFGVQGSCFLSSLSEAQSPTAADPLQQAYAGVQQYAAFPAAYGQISQAFPQPPPIIPQQQREGPEGCNLFIYHLPQEFGDGELMQMFLPFGNVISSKVFVDRATNQSKCFGFVSFDNPGSAQAAIQSMNGFQIGMKRLKVQLKRPKDANRPY
RNA-binding protein that may be implicated in the regulation of pre-mRNA alternative splicing.
Q6DGV1
A0A1D8PQG0
NAG3_CANAL
Transmembrane protein 1
Candida
MSDNTTLDNISVNSEKVVDYTIHHDDRKELERLVSHNKGVEKIVSELAEGAGQLGPLEQPYDIHKVETHPDPHTDYNDADPWKYPIDKETKLRLVDWTEGDKHNPKNFGKGFKWLCTVLLGMICFVVALGSAIVTGDLERPAADFGVSEEVIILASVTMFVIGFGVGPLVFAPMSEEVGRKPIYVVTLFVAVVFIVPCGAAQNIATLLICRLIDGTAFSAPMTLIGGSLADIWEGPERGTAMAVFSAAPFLGPVCGPIFGGLLCDYAPTWRWVYWTFLIVAGFFYVVFIVVVPETHHGILLKKRAKKLRKDTGDSRYRSFNELQIRTFAQVAKTSLLRPFVLLSELIVFLVTMYMSVLYGLLYMFFFAYPIVYQEGKGWSASKTGVMFIPIGVGVIASSLAAPFFNKDYNRRAQEYRDRGELPPAELRLIPMMIGCWFVPAGLFAFAWSSYQRLSWAGPCFSGFAVGFGFLLLYNPANNYIVDSYQHYAASALAAKTFVRSIWGACVPLFTIQMYHRLGDEWATSLMAFISLACCAIPYLFYIFGARIRTFSKYAYAPNMD
MFS transporter involved in N-acetylglucosamine (GlcNAc) uptake . Confers resistance to cycloheximide, 4-nitroquinoline-N-oxide, and 1,10-phenanthroline, and contributes to virulence .
A0A1D8PQG0
O14981
BTAF1_HUMAN
TBP-associated factor 172
Homo
MAVSRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSANWDTRIAAGQAVEAIVKNVPEWNPVPRTRQEPTSESSMEDSPTTERLNFDRFDICRLLQHGASLLGSAGAEFEVQDEKSGEVDPKERIARQRKLLQKKLGLNMGEAIGMSTEELFNDEDLDYTPTSASFVNKQPTLQAAELIDSEFRAGMSNRQKNKAKRMAKLFAKQRSRDAVETNEKSNDSTDGEPEEKRRKIANVVINQSANDSKVLIDNIPDSSSLIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKSGGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGGLLGIKYALAVRQDVINTLLPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQTQKVPFIINTLWDALLELDDLTASTNSIMTLLSSLLTYPQVQQCSIQQSLTVLVPRVWPFLHHTISSVRRAALETLFTLLSTQDQNSSSWLIPILPDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYVVAAACPWMGAWLCLMMQPSHLPIDLNMLLEVKARAKEKTGGKVRQGQSQNKEVLQEYIAGADTIMEDPATRDFVVMRARMMAAKLLGALCCCICDPGVNVVTQEIKPAESLGQLLLFHLNSKSALQRISVALVICEWAALQKECKAVTLAVQPRLLDILSEHLYYDEIAVPFTRMQNECKQLISSLADVHIEVGNRVNNNVLTIDQASDLVTTVFNEATSSFDLNPQVLQQLDSKRQQVQMTVTETNQEWQVLQLRVHTFAACAVVSLQQLPEKLNPIIKPLMETIKKEENTLVQNYAAQCIAKLLQQCTTRTPCPNSKIIKNLCSSLCVDPYLTPCVTCPVPTQSGQENSKGSTSEKDGMHHTVTKHRGIITLYRHQKAAFAITSRRGPTPKAVKAQIADLPAGSSGNILVELDEAQKPYLVQRRGAEFALTTIVKHFGGEMAVKLPHLWDAMVGPLRNTIDINNFDGKSLLDKGDSPAQELVNSLQVFETAAASMDSELHPLLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEKVLPWLGAIDDSVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKFCSREYLNPLHYTGPPTERIRLQHQVKRHNLIVASYDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSATLSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLGNGSTSESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDGKAEKADTSTSGKASMKSILENLSDLWDQEQYDSEYSLENFMHSLK
Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner.
O14981
Q03W30
RSMH_LEUMM
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Leuconostoc
MPFEHVTVLLHEAIALLDIKPEGTYVDATLGGGGHTGEILKQLTTGTLYSFDQDDTAIQYNAEQYADEIAAGKLVIIHKNFRTLTSALADYGVTAVDGIVYDLGVSSVQFDDGQRGFSYKYDAELDMRMDQRQALTAKTIVNEWPFNELMRVLSRYGEDRFPKQIARKIEQHRENAPINTTFELVDIIKEAIPAPARRKGGHPAKRSFQAFRIAVNDELGALEDSLTQALELLATDGKISVITFQSLEDRLVKQMFREKSSAPELPAGLPVLPGQFEADYELLTRKPISPSTEEMAINHRAESAKLRGIRRK
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
Q03W30
A1E9Z6
PSBM_AGRST
Photosystem II reaction center protein M
Agrostis
MEVNILAFIATALFILIPTAFLLIIYVKTASQND
One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface.
A1E9Z6
Q2JCG8
TAL_FRACC
Transaldolase
Frankia
MSNPLSELSAAGVAVWLDDISRDRLRTGNLAHLVENRGVVGVTSNPTIFQKAISSSDLYDEQLHDLAIRGVDVGEAVRAITAADVRDACDVLRGVYDASGGVDGRVSLEVDPRLAHEAERTLAEARALWWLVDRPNLFIKIPATRAGLSAITETLAQGISVNVTLIFGLDRYDAVIDAFMTGLEKALAAGRDITDLASVASFFVSRVDTEVDQRLEKIGTSEAKALRGRAAVANARLAFERYEKAFATPRWAALAAAGAKPQRPLWASTSTKDPSLPDTIYVTELIAPGTVNTMPEATLEAFADHGSVTGETIRPRYEEAHEVFAQLTAVGIDLDDVIETLESQGVQKFEDSWTQLLDTIAAHLGSAGSSA
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
Q2JCG8
A1WU59
IHFA_HALHL
Integration host factor subunit alpha
Halorhodospira
MSLTKADMAERLFEEVGLNKREAKELVELFFEEIRTALENGEPVKLSSFGNFELRDKNERPGRNPKTGEEIPISARRVVTFRPGQKLKSRVESYAGTREEQ
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
A1WU59
B4S4T8
PAND_PROA2
Aspartate 1-decarboxylase alpha chain
Prosthecochloris
MRLHLLKSKIHNAIVTSGDLEYEGSITIDSQLLELADMLPNEKVLCVNNNNGERFETYIIKGKAGSREIQLNGAAARCALPGDEIIIMTFAEIEAEKAKDFKPMILIVDHQNNPKRRHLVGEEDTPLPH
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
B4S4T8
P74180
FTSW_SYNY3
Peptidoglycan polymerase
unclassified Synechocystis
MITAANLLRIIFPFYDPEVLRWSGEARLMRTLFFAWMAMGVVVLFSASYAESLDTSGTGLSIILKQIAYLWLGLNIFNFLVRLPLQVCLKLVPWFLIVVLLLIFLTKSGLGVEVNGARRWISLGPILIQPSEFMKPCLVLQAANLFGNWHRFPWRSRLIWLGIFALTLGSILLQPNLSTTALCGMGLWLIALASGLPWIYLISTALLGITTAVTSISIRDYQRARVTSFLDPFADPRGDGYQLVQSLYAIASGGVLGRGFGMSQQKLFYLPIQTTDFIFAVFAEEFGLVGCITFLAFLGLFTTMGLRVAMRCRHRVKRLIGLGVVIFLVGQSLLNIGVASGALPTTGLPLPFFSYGGSSCLSSLVLAGLLVRVARESNEAEVIPLGTKTAPAV
Peptidoglycan polymerase that is essential for cell division.
P74180
A4QL18
PSAB_DRANE
PsaB
Draba
MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFETWIQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSALSLIGGWLHLQPKWKPRVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGEYVRWNNFLNVLPHPQGLGPLFTGQWNLYAQNPDSSSHLFGTSQGSGTAILTLLGGFHPQTQSLWLTDMAHHHLAIAILFLIAGHMYRTNFGIGHSIKDLLEAHIPPGGRLGRGHKGLYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISQLSWASLFLGFHTLGLYVHNDVMLAFGTSEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTNGPAFNAGRSIWLPGWLNAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWKDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
A4QL18
Q4KGL6
CYNS_PSEF5
Cyanate lyase
Pseudomonas
MLQSQFAQAPRLALADTIIDAKARKNLSWQDLTDGTGLSLAFVTAALLGQHALPATAADLVCDKLGLDQDASRLLQSIPLRGSIAGGIPTDPTVYRFYEMLQVYGSTLKALVHEQFGDGIISAINFKLDIKKVEDPEGGSRAVITLDGKYLPTKPF
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
Q4KGL6
Q8CG19
LTBP1_MOUSE
Transforming growth factor beta-1-binding protein 1
Mus
MAGAWLRWGLLLWAGLLAWSAHGRVRRITYVVRPGPGLPAGALPLAGPPRTFNVALDARYSRSSTAASSRALAGPPAERTRRTSQPGGAALPGLRSPLPPEPARPGGPSRQLHSKAGAQTAVTRFAKHGRQVVRSQVQQDAQSAGGSRLQVQQKQQLQGINVCGGQCCHGWSKPPGSQRCTKPSCVPPCQNGGMCLRPQLCVCKPGSKGKACEITAAQDTMPPAFGGQNPGSSWAPLEQAAKHTSTKKADTLPRVSPVAQMTLTLKPKPSMGLSQQIHPQVAPLSSQNVMIRHGQTQEYLLKPKYFPAPKVVSAEQSTEGSFSLRYGQEQGTAPFQVSNHTGRIKVVFTPSICKVTCTKGNCQNSCQKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVLGASMPKLYQHAQQQGKALGSHVIHSTHTLPLTMTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDSPGGQKVKEAQPGQSQVSYQGLPVQKTQTVHSTYSHQQLIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKQSYHGYTQMMECLQGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCSCKMGFGPDPTFSSCVPDPPVISEEKGPCYRLVSPGRHCMHPLSVHLTKQICCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHQHIGKEAVYVKPKNTQPVAKSTHPPPLPAKEEPVEALTSSWEHGPRGAEPEVVTAPPEKEIPSLDQEKTRLEPGQPQLSPGVSTIHLHPQFPVVVEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYKFSEQLRKCVDIDECAQVRHLCSQGRCENTEGSFLCVCPAGFMASEEGTNCIDVDECLRPDMCRDGRCINTAGAFRCEYCDSGYRMSRRGYCEDIDECLKPSTCPEEQCVNTPGSYQCVPCTEGFRGWNGQCLDVDECLQPKVCTNGSCTNLEGSYMCSCHRGYSPTPDHRHCQDIDECQQGNLCMNGQCRNTDGSFRCTCGQGYQLSAAKDQCEDIDECEHHHLCSHGQCRNTEGSFQCVCNQGYRASVLGDHCEDINECLEDSSVCQGGDCINTAGSYDCTCPDGFQLNDNKGCQDINECAQPGLCGSHGECLNTQGSFHCVCEQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRVTEDSGVDRQPREEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVQGTAEFTEMCPRGKGLVPAGESSYDTGGENYKDADECLLFGEEICKNGYCLNTQPGYECYCKQGTYYDPVKLQCFDMDECQDPNSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCVQPTESNEQIEETDVYQDLCWEHLSEEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPMKDSDDYAQLCNIPVTGRRRPYGRDALVDFSEQYGPETDPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDMAKMTCVDVNECSELNNRMSLCKNAKCINTEGSYKCLCLPGYIPSDKPNYCTPLNSALNLDKESDLE
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta.
Q8CG19
A7FVZ3
IF2_CLOB1
Translation initiation factor IF-2
Clostridium
MAKIRVYELAKELNISSKELITLLEEEFSVEVKNHMSAIEDEDANLIKELLSGKEKSEKTKEEDDEIETTAKNPIKESMNNKKSNKRDDKNEKVNTENAEDMGIITMTSDTITVKEISDKLEKSYAEVIKELMLMGVMASVNQEINFEMAEKLAAKFDMEILKEDEDEKEDLEDILKDNEEEEYLQKRSPIITVMGHVDHGKTSLLDAIRKSKVTSTEAGGITQHIGAYTVELNGEAITFLDTPGHAAFTAMRARGAQVTDIVILVVAADDGIMPQTQEAISHCKAANVPLIVAINKIDRPGANIDKVKQELTEYGLVAEDWGGDTICVPVSAHTKEGIDDLLEMILLSSEILELKANPNRKAKGTVVEAKLDKGRGPVATLLIQNGTLRVGDSIVVGSTYGRIRAMFNDKGRNIESAGPSTPVEILGLSEVPEAGDKFYQVKEEKTARGIADKRKEKIRDEYLQSTHKVSLEDLYNQIQEGTVKELGLIVKADVQGSVEALKQSLEKLSTEEVKVRVIHGGVGAINETDVTLATASNGIILGFNVRPDNNAIIASERDGVDIKTYRVIYDAIEDIKSAMLGMLEPEFKEVVIGTAEVRQVYKISSVGTIAGAYIQTGKLARNAGARVIRDGIVIFESELASLKRFKDDAKEVAQGYECGLSIEKFNDIKEGDIIECFIMEEIKKKTL
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
A7FVZ3
P83220
MIH_JASLA
Probable molt-inhibiting hormone
Jasus
RFTFDCPGMMGQRYLYEQVEQVCDDCYNLYREEKIAVNCRENCFLNSWFTVCLQATMREHETPRFDIWRSILKA
Inhibits Y-organs where molting hormone (ecdysteroid) is secreted. A molting cycle is initiated when MIH secretion diminishes or stops. Has little or no hyperglycemic activity.
P83220
A6LCQ4
HCP_PARD8
Prismane protein
Parabacteroides
MFCYQCQETAQGKGCTLKGVCGKTAEVAGLQDLLMYLMKGISKLTTTLRKQGVESSTANKFIVDGLFMTITNANFDSSRFVSKIKEAYQLRENLLNELHRLGIHLSLTCDCLTWKSDKVEEMEVKAKEVGILATENEDIRSLCELLTYGVKGMAAYVEHAYNLGFEDTSLYAFMQDALVATTRSDLTVADLTQWVLTCGEYGVKAMALLDKANTSTYGNPEITKVNIGVGKNPGILISGHDLRDIQDLLEQTEGTGIDVYTHGEMLPAHYYPAFKKYKHFVGNYGSAWWKQTSDFETFNGVILFTTNCLVPPRSSATYADRVYTTGSTGFEGFPHIADRKPGGSKDFSALIEHAKKCAPPTEIEHGEIIGGFAHEQVFQLADKVIDAVKSGAIRKFFVMAGCDGRMKSRSYYTEFAEKLPKDTVILTAGCAKYRYNKLPLGEIRGIPRVLDAGQCNDSYSLVMIALKLKEIFGLDDVNELPIAYNIAWYEQKAVIVLLALLYLGVKNIHLGPTLPAFLSPNVAKVLVDNFGIAGIGSVDEDMELFLGK
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
A6LCQ4
Q11HP9
EFG_CHESB
Elongation factor G
unclassified Chelativorans
MAREFKIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWKGRDEKLRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQADKYHVPRMIFCNKMDKIGADFYRSVEMVKSRLGATAVVMQLPIGAESDFKGVIDLVEMKALIWRDETLGAAWDVVEIPAEFKEKAEEYREKLIEAAVEMDEGAMERYLEGEMPSIEEIRALVRKGTIEVKFFPMFCGSAFKNKGVQPLLDAVVDFLPSPIDIPAIKGVDAKTEEPIERHAEDSEPLSMLAFKIMNDPFVGSLTFCRIYSGVLKKGVSLENTVKGKRERIGRMLQMHANSREDIEEAYAGDIVALAGLKETTTGDTLCDPLKPVILERMEFPEPVIQIAIEPKTKGDQEKMGLALNRLAAEDPSFRVKTDEESGQTIIAGMGELHLDIIVDRMKREFKVEANIGAPQVAYRETITKTAEIDYTHKKQTGGSGQFARVKIVFEPNPDGEDFLFESKIVGGSVPKEYVPGVQKGIESVLSSGPIAGFPMLGVKATLVDGAYHDVDSSVLAFEIAARAAFREGAQKAGAQLLEPIMKVEVVTPEEYVGSVIGDLNSRRGQIQGQEARGVAVVVNAMVPLANMFKYVDNLRSMSQGRAQYTMQFDHYEPVPSAVAQEIQKKFA
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
Q11HP9
Q5R6J1
S6A19_PONAB
System B(0) neutral amino acid transporter AT1
Pongo
MVRLVLPNPGLDTRILSLAELETIEQEEASSRPKWDNKAQYLLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRRGSLGVWSSIHPALKGVGLTSMLVSFVVGLYYNTIISWIMWYLFNSFQEPLPWSECPLNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWRMLLCLACAWSVLYMCTIRGIETTGKVVYITSTLPYVVLTIFLIRGLTLKGATKGIIYLFTPNVTELANPVTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCERDSVIVSIINGFTSVYVAIVIYSIIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVEMQRQCNASNPAAYAQLVFQTCDINSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLKVIPPKWPKELLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAVSIPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIILVFFFVVQVSQELTYSIWNPGYEEFPKSQKISHPNWVYAVVVIVAGVPSLTIPSYAIYKLIRNCCQKPGDRQGLVSTLSTASMNGDLKY
Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This uptake is sodium-dependent and chloride-independent. Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity.
Q5R6J1
A8F2V3
IF1_RICM5
Translation initiation factor IF-1
spotted fever group
MIMSKDDLIQFTGTVLELLPNATFRVKLENDHVIIAHTAGRMRKNRIRILLGDKVMVEMTPYDLTKGRVIHRH
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
A8F2V3
Q96375
ABA2_CAPAN
Xanthophyll epoxidase
Capsicum
MYASSARDGIPGKWCNARRKQLPLLISKDFPAELYHSLPCKSLENGHIKKVKGVKATLAEAPATPTEKSNSEVPQKKLKVLVAGGGIGGLVFALAGKKRGFDVLVFERDISAIRGEGQYRGPIQIQSNALAALEAIDMDVAEEIMNAGCITGQRINGLVDGISGNWYCKFDTFTPAVERGLPVTRVISRMTLQQILARLQGEDVIMNESHVVNFADDGETVTVNPELCQQYTGDLLVGADGIRSKVRTNLFGPSELTYSGYTCYTGIADFVPADIDTAGYRVFLGHKQYFVSSDVGGGKMQWYAFHNEPAGGVDAPNGKKERLLKIFGGWCDNVIDLSVATDEDAILRRDIYDRPPTFSWGKGRVTLLGDSVHAMQPNLGQGGCMAIEDSYQLALELEKAWSRSAESGSPMDVISSLRSYESARKLRVGVIHGLARMAAIMASAYKAYLGVGLGPLSFITKFRIPHPGRVGGRFFIDLGMPLMLSWVLGGNGEKLEGRIQHCRLSEKANDQLRNWFEDDDALERATDAEWLLLPAGNSNAALETLVLSRDENMPCTIGSVSHANIPGKSVVIPLSQVSDMHARISYNGGAFLGTAFRSDHGTWFIDNEGRRYRVSPNFPMRFHSSDVIVFGSDKAAFRIKAMKFAPKTAAKEDRQAVGAA
Converts zeaxanthin into antheraxanthin and subsequently violaxanthin. Acts also on beta-cryptoxanthin. Involved in the epoxidation of zeaxanthin.
Q96375
P24754
OMPA_ATLHE
Outer membrane protein 3A
Atlantibacter
LTAKLGYPITDELDIYTRLGGMVWRADSKYNIPGGASFKDHDTGVSPVFAGGLEWAVTRDIATRLEYQWTNNIGDANTVGTRPDNGLLSVGVSYRFGQQEAAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQQALDQMYTQLSNLDPKDGSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSDKISARGMGESNPVTGNTCDNVKPRAALIDCLAPDRRVEIEVKGI
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.
P24754
Q3YRU2
DUT_EHRCJ
dUTP pyrophosphatase
Ehrlichia
MKNNTDILIKVIKLNSNNLPLPSYSTENSSGMDLYSAMTQDVILAPGCRACINTGIAISVPNGYEAQVRPRSGLALKFGITVLNTPGTIDADYRGEIKVILINLGHETYTIKYGDRIAQMVIAPVIHASWNLVKDLDDDTTKRGDQGFGSTGI
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Q3YRU2
D4D675
MCPAL_TRIVH
Metallocarboxypeptidase A-like protein TRV_02598
Trichophyton
MQSLLLLATLLGSALGGAIPSQSANYNGYKVMRVSGDDTSKISHIVSKLGLETWKFPKAANANVDIVVPPKKVAEFEKMSHAAGLKKQVMHENLGDSIKSEMSFRPYSCELLTLDGGANDTWFQSYHKYEDHLKFMQDFQSAHSQNSEIVTSGKSHEGRDITGVHVWGSGEKGSKPAVVFHGTVHAREWITTMTVEYILAQLFDDKEAGAALLEKFDFYIFPIANPDGFVFTTESDRMWRKNREQNEGGCYGTDLNRNWPYKWEGDGSTTDPCSETYRGPSPGFAPETKASTSFIKGLADGAGVKMFVDWHSYSQLFMTPYGYSCSARAPNDDVLQEMASSFADAVKAVHGTSFTTGPICNTIYQANGNSVDWIVDEIKGETAFAAELRDTGMYGFVLPPEQIIPSGEETWAGVKAMFSKLK
Extracellular metalloprotease that contributes to pathogenicity.
D4D675
Q39DH2
PDXH_BURL3
Pyridoxal 5'-phosphate synthase
Burkholderia cepacia complex
MTTLADLRINYSRASLDEADVAHDPFAQFDRWFKEALAAKLPEPNTMTLATVGDDGRPSARIVLIKGVDERGFVFFTNYESRKGRDLAAHPQAALLFYWIELERQVRIEGRIEKTSAEESDRYFASRPLGSRIGAWASEQSAVIDSRATLEAQEQAVSERYGDNPPRPPHWGGYRLVPDSIEFWQGRPSRLHDRLLYTRDADTSPSWSISRLSP
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
Q39DH2
B9HBA8
ACCC1_POPTR
Acetyl-coenzyme A carboxylase biotin carboxylase subunit A 1
Populus
MEATLPVCKSVTSTPGLFMGKTSGIRSSQCSFMMGNKVNFPRQRAQTAHVHCAKNGGALGVTCRAEKILVANRGEIAVRVIRTAHEMGIPCVAVYSTIDKDALHVKLADESVCIGEAPSSQSYLVIPNVLSAAISRRCTMLHPGYGFLAENAVFVEMCREHGINFIGPNPDSIRVMGDKSTARETMKKAGVPTVPGSDGLLQSTEEGVRLANEIGYPVMIKATAGGGGRGMRLAKEPDEFVKLLQQAKSEAAAAFGNDGVYLEKYVQNPRHIEFQVLADKFGNVVHFGERDCSIQRRNQKLLEEAPSPALTPELRKAMGDAAVSAAASIGYIGVGTVEFLLDERGSFYFMEMNTRIQVEHPVTEMISSVDLIEEQIRVAMGEKLRYKQEDIVLRGHSIECRINAEDAFKGFRPGPGRITAYLPSGGPFVRMDSHVYPDYVVPPSYDSLLGKLIVWAPTREKAIERMKRALDDTIITGVPTTIDYHKLILEIEDFKNGNVDTAFIPKHEKELAAPQQIIPAKQLTNSAA
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
B9HBA8
Q1QQS4
ATPD_NITHX
F-type ATPase subunit delta
Nitrobacter
MAAVDSSVSGVSGRYATALFELAREDKSIDAVKADLDRFDAMLADSPELARLVRSPVFSADTQAKALAAVLDKAGFGGTTAKFLKVLTANRRLFAVTEVIRAFRALVARFKGEVTAEVTVAETLNKKNLDALTTALKSVTGKDITLNVKVDPSIIGGLVVKLGSRMVDSSLRTKLNSIKHAMKEAG
This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
Q1QQS4
C1FTF1
GLYA_CLOBJ
Serine hydroxymethyltransferase
Clostridium
MDFTNLKNTDPELLDMIKKEEERQEYNIELIASENFTSLSVMEAMGSLLTNKYAEGYPHKRYYGGCEFVDEVEDLARERLKKLFAAEHANVQPHSGSQANMAVYMSVLQTGDTILGMDLSHGGHLTHGSPVNFSGKLYNFISYGVDKETETIDYEKLKKIALENRPKMIVSGASAYPRIIDFQKIREICDEIDAYMMVDMAHIAGLVATGLHPSPVPYADFVTTTTHKTLRGPRGGAILCKEKYAKAVDKAIFPGIQGGPLMHTIAAKAVCFGEALREDYKEYMQQVVKNTKVLGEELKNYGFRLISGGTDNHLLLIDLTNKNITGKDAEKLLDSVGITVNKNTIPFETLSPFITSGIRIGTPAVTTRGFKEEEMKKIAYFMNYSIEHREENLSQIKEQIKEICKKYPLYQNA
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
C1FTF1
Q8DDK6
FADB_VIBVU
3-hydroxyacyl-CoA dehydrogenase
Vibrio
MIYQAETLQVKEVQDGVAEILFCAPNSVNKLDLATLASLDKALDALTAHSGLKGVMLTSDKEAFIVGADITEFLGLFAKPEEELDQWLQFANSIFNKLEDLPVPTVAVVKGHTLGGGCECVLATDLRIGDKTTSIGLPETKLGIMPGFGGCVRLPRVIGADSAMEIITQGKACRAEEALKIGLLDAVVDSDRLYASALQTLTDAINEKIDWKARRQQKTSALTLSKLEAMMSFTMAKGLVAQVAGPHYPAPMTAVVTIEEGARFARNQALDIERKHFVKLAKSEEAKALVGLFLNDQYIKGIAKKAAKSANKETQRAAVLGAGIMGGGIAYQSALKGVPVIMKDIAQASLDLGMTEASKLLNKQLERGKIDGFKMAGILASITPSLHYAGIDNADIIVEAVVENPKVKAAVLSEVEEQVSEETVLTSNTSTIPINLLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGEHTSDETINRVVAYAAKMGKSPIVVNDCPGFFVNRVLFPYFGGFSMLLRDGADFTQIDKVMERKFGWPMGPAYLLDVVGIDTAHHAQAVMAQGFPERMGKQGRDAIDALFEANKYGQKNGSGFYTYTMDKKGKPKKAFSDEIVPILAPVCAAQQAFDDQTIIQRMMIPMINEVVLCLQEGIIASAQEADMALVYGLGFPPFRGGVFRYLDSVGIANFVAMAQQHVELGAMYQVPQMLIDMAEKGQTFYGAQQQGSI
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
Q8DDK6
Q8FSF7
HEM3_COREF
Pre-uroporphyrinogen synthase
Corynebacterium
MTLRIGTRGSKLATTQAGHMRDRLKHFGRDAELTIVTTPGDVNMSPVERIGVGVFTQALRDALVADEIDVAVHSFKDLPTAPDPRFHLVVPTRADARDALIARDGLTLEELPEGAKVGTSAPRRISQLKALRPDLEILPLRGNIDTRMGKVTSGELDAVVLAFAGLSRVGMQDRATQVFDPDMLMPAPAQGALAIECRVEDEDIITGLNMLMHADTYVTAVAERTVLNRLEAGCTAPVAAHATLDGYAGDTMTLTAGVFALDGSEQLVFSAQGAGERPEELAEQVAAQLIEQGAATLLG
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Q8FSF7
Q0V6M5
LCPS_PHANO
Phytoene synthase
Parastagonospora
MGFDYAIVHVKYTIPPAVLLTLLYRPLFTKLDAFKVLFLVTVAVTATIPWDSYLIRTNIWSYPDHVVIGPTLLDIPLEEVFFFFIQTYNTTLLYLILSKPTFQPAYLRAGRPTASSPWKYQKLAGQLFLVGATVWAGLRVHENAKGTYTGLIVVWAAPIILLQWTLAYQFILGLPWTNTVLPIAIPTLYLWLVDTLALRRGTWVISPGTKYGVHLWDGLEIEEALFFFVTNTLIVFGQLAFDNALAVLYTFPALFPKPPSMPTPLDLINALWVSPYKYDRARLAGLQDAVLRLKRKSRSFYLASATFPGPLRSDLLLLYSFCRVADDLVDNAATAEEAKEWISKLHQYLDLVYSDAKSSTVSEDFVQAHFPSDARSALLQLPAHKLPRQPLQDLLHGFEMDLAFNTSSPIKTETDLRLYSERVAGTVAQMCIELIFRLYPSNMTSGEERKVVDAGNQMGMALQYVNIARDISVDAHIGRVYLPLDWLQESGLTYDEVLISPEGARMESLRMRLLEKAFSIYDGARGAIETLPVEARGPIRVAVESYMEIGRTLRQKGYTVRAGRATVSKWRRVIVAWRTLNKSIA
Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).
Q0V6M5
Q889Y0
RL10_PSESM
50S ribosomal protein L10
Pseudomonas
MAIKLEDKKAIVAEVNEAAKAGLSAVVADARGVTVGAMTGLRKEAREAGVYVRVVRNTLLKRAVADTEFSVLNDVFTGPTLIAFSNEHPGAAARLFKEFAKGQDKFEIKAAAFEGKFLAANQIDVLATLPTRNEAISQLMSVIQGATSKLARTLAAVRDQKEAAAA
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
Q889Y0
Q9HAV4
XPO5_HUMAN
Ran-binding protein 21
Homo
MAMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQVAIVRHFGLQILEHVVKFRWNGMSRLEKVYLKNSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNEQELQLGAAECLLIAVSRKGKLEDRKPLMVLFGDVAMHYILSAAQTADGGGLVEKHYVFLKRLCQVLCALGNQLCALLGADSDVETPSNFGKYLESFLAFTTHPSQFLRSSTQMTWGALFRHEILSRDPLLLAIIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFNAFFNSSRAQQGEVMRLACRLDPKTSFQMAGEWLKYQLSTFLDAGSVNSCSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDGIELLQMVLNFDTKDPLILSCVLTNVSALFPFVTYRPEFLPQVFSKLFSSVTFETVEESKAPRTRAVRNVRRHACSSIIKMCRDYPQLVLPNFDMLYNHVKQLLSNELLLTQMEKCALMEALVLISNQFKNYERQKVFLEELMAPVASIWLSQDMHRVLSDVDAFIAYVGTDQKSCDPGLEDPCGLNRARMSFCVYSILGVVKRTCWPTDLEEAKAGGFVVGYTSSGNPIFRNPCTEQILKLLDNLLALIRTHNTLYAPEMLAKMAEPFTKALDMLDAEKSAILGLPQPLLELNDSPVFKTVLERMQRFFSTLYENCFHILGKAGPSMQQDFYTVEDLATQLLSSAFVNLNNIPDYRLRPMLRVFVKPLVLFCPPEHYEALVSPILGPLFTYLHMRLSQKWQVINQRSLLCGEDEAADENPESQEMLEEQLVRMLTREVMDLITVCCVSKKGADHSSAPPADGDDEEMMATEVTPSAMAELTDLGKCLMKHEDVCTALLITAFNSLAWKDTLSCQRTTSQLCWPLLKQVLSGTLLADAVTWLFTSVLKGLQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEIQKDSLDQFDCKLLNPSLQKVADKRRKDQFKRLIAGCIGKPLGEQFRKEVHIKNLPSLFKKTKPMLETEVLDNDGGGLATIFEP
(Microbial infection) Mediates the nuclear export of adenovirus VA1 dsRNA.
Q9HAV4
Q39XZ9
RL16_GEOMG
50S ribosomal protein L16
Geobacter
MLMPKRVKYRKQMKGRMTGAAMRGATLSYGDFGLQATECGWVDSRQIEAARIAMTRYIKRGGKIWIRMFPDKPLTSKPAETRMGKGKGSPDSWVCVVKPGKVLYEMEGVSEEIAREAFRLAANKLPVGTKFISRKEGYES
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
Q39XZ9
O13682
SWR1_SCHPO
Helicase swr1
Schizosaccharomyces
MTYEESEKNKNGLSSYIKKEGSSDLKVRVRFREPKLLVTHSGHITEQPKYEHLEQYLDSYVSLEDGDHDPKEAKELVFREVQLRHRINEFRKKGYFTAEAPVELKKAPSSNNIPISYRDNLLSHVNGYARSMHNDRKVRASRSRRISGMILAHFKRLSGADEKKAKEEDKRIRLLAKRTAWEIRKKWKVIEREVRRRRAERAAEAQRVAGKEQLANILKHSTDLLEARIERANINISAQTSESAVDWNYLLKTSDDLLSVDELKLKYSNPDLIKNIEREEEAEETSDDEPLSSEDEENEDEDITEESNLRKRKVSDKTRVVNKHPPSLRRSRRFFAKKSYNHVSDLDGEVIVMKKEDITDGVSTKKDLNDGDQNEVPLHDTGSSSSLSLLYNEDVASKKKRRVNDDGLARKKSIAGISEQRKFDEPNGSPVLHANKIQVPFLFRGTLREYQQYGLEWLTALHDSNTNGILADEMGLGKTIQTIALLAHLACEKENWGPHLIIVPTSVMLNWEMEFKKFLPGFKILTYYGNPQERKEKRSGWYKPDTWHVCITSYQLVLQDHQPFRRKKWQYMILDEAHNIKNFRSQRWQSLLNFNAEHRLLLTGTPLQNNLVELWSLLYFLMPAGVTQNNSAFANLKDFQDWFSKPMDRLIEEGQDMNPEAMNTVAKLHRVLRPYLLRRLKTEVEKQMPAKYEHVVYCQLSKRQRFLYDDFINRARTREILASGNFMSIINCLMQLRKVCNHPNLHEERPIVTSFALRRSAIADLEIKDLLVRKRLLHEEPMTKLDLSTLRLIRTDSEAFDTFVSDELNSLCATNAYNRISTFLRMQIDEECKPCQFKKSNFKEHFQNKIYQEQLDKLNFQKYLNESKCSHSPIYGSNLIRLAEKLPKHSTSIDYTLYAKDDPLYLLNTTKALRSCILSTEERASNMKEIIQRFACITPKAVVVDLPELFCKTIPRDLLYEVSRKINPLHQASTRLAIAFPDKRLLQYDCGKLQVLDRLLKDLVSNGHRVLIFTQMTKVLDILEQFLNIHGHRYLRLDGATKIEQRQILTERFNNDDKIPVFILSTRSGGLGINLTGADTVIFYDSDWNPQLDAQAQDRSHRIGQTRDVHIYRLISEYTVESNMLRRANQKRMLDKIVIQGGEFTTEWFRKADVLDLFDLDDESLKKVKADSDSGSTKNEENWEVALAAAEDEEDVQAAQVARKESALEQTEFSETSTPQAMLTKDSTPLSSDSATPGFERDSTEEQSNTNDMDEDRSELEEDLDETVGHIDEYMISFLEQEGTSDEW
Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.
O13682
P37885
SOMA_VICPA
Growth hormone
Vicugna
FPAMPLSSLFANAVLRAQHLHQLAADTYKEFERTYIPEGQRYSIQNAQAAFCFSETIPAPTGKDEAQQRSDVELLRFSLLLIQSWLGPVQFLSRVFTNSLVFGTSDRVYEKLKDLEEGIQALMRELEDGSPRAGQILRQTYDKFDTNLRSDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFVESSCAF
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
P37885
O45657
PLX2_CAEEL
Plexin-2
Caenorhabditis
MLPESVFLLLISHFLRAVTQPPFETEGVKQKLFHFSGHIDDFIVSRDQQTIYVASLNRLTSLSISNFSIQHEVSLGPVQDSPWCSADGKSCLKDNRPFPTDVRTKILQILPTNQILQCGSVKLGSCSTFNSKLSLITESTIAVAANSPDASTVSKIIDNRLIVAASATKESPYRDPFPAVAIRNLPGLNVENAGDLEGEAAVFLRAAYKNAFKFLYTFTHQHFVFVVAMVTPRESRLPMTTRLIRFCRNDTKFESYSEIELQCRGEDNTNYPFLNAIIQSYDKLIASFSTSSTSPKSSICVFSMQKVKLTFWYNVDRCRSGTDSIRLPHIGRDTKCVNKAHIPLDEDSCELGVGGSIELVEMSTKDIMGKVTSLMAVDQKAIFAGTTTSQIVMFKWDEHHSNQLEEYGRKEVGDGRTGSEVSKMVKFGDFVIVQMPYGIILEELSTCSHHSSCTECLVSVDPLCQWCHPTQSCTTSARCTSPVTSQCPIVDGDPIPSIVSVNSSTPISFNIHHLPPPVGFTYRCQFGTSTSSIKANWTTTGVSCPSEIFTSPNTFEILLLTSISNNPISRHNFTVYDCSGYGTCSSCMSSEYNCAWCSGLHKCSNSCGALEKSKACVKIQPMRLPIAIGSQQEIVLEASNLDTLDRRHEHFCKVNEQVSLAKIASDSIRCGKIQLTLSNTTSANMVVPLSLITRDSVIDIANVSLYSCTNLASDCSSCLALSPSLSCGWCNRQCSHECHESKATAVCDPPRIDKFEPTSGPIEGGTIIKIYGNDLGMSVEDVRGKIYVAGSRCNIVEYHVSNMIACQVDKGVSSGPIRISVGRATVAVAESSELYSFVRTSIFSAYPLYGPISGGTRITLYGQNLSSGSQTSVTVGGMPCPIERVNSSTVLTCLTPSGTRIGKSARVVVHVDHSQTQLDQPFEYRSDPSISSIFPMTSFKAGGRIVYVQGNSLNTVQTAKLFLISSPTPPFYIISDLAPCHIINSTLMTCMTPKILETITRRVEYTRQPMGIYPNPTLSPFKGVRYHQGEQSLILEGHNLNLAAEPNDFKIFIGNERCYVTLVDVRQLVCSGPVRQPKATDERGIPINGDNPLVTVIVGSLRMELGLIEYSDHALPSRLSLLILGLLLFIVVTLTVMCLVFKRRRQEREKEYRKIQLQMENLENNVRKECKQAFAELQTNLVLSPKSANSVNLGPELINFPHFVENLLWSDNNLTSAPSLARTLPVTLAQFHALLSFKGFIFTIVEAAESDVSISTSEKSMLASLLISVLLRNFSYCTEVVVDLLRAHIARSVQNKRAELLFRNSDSVVEKMFSKWMSICLYSHLTPQMNSYFYLYKALQYQTDKGPVDAVTGDARYTINEAKLLRESVDTKTLKIRVIPFEKCDESIDLEVHACDAICQVKQKVASAVYRETPYSQRPRITQFELKYKCPKRGDVKLTDVLPIETLSQKKLPVKLFTLADYGISDGCTLEMSPAVYTAESYRNSLADSGQSSWSSLDRCSPIYSSSKYYHLTNPSSGTMTFKKKSSNDSNLLPKSIPEVYLTRLLTSKGTVETYVEDFLESVLYMHDSSYPPILKFFFDILDREASVNGVSENICQQWKANGYVLRVWANFVRNPQLVFDVPHSISMDANLSTVAQTMMDCFSFSEPVLGAHSPSSRLLFAKDVARLRPLSVDLFKRVKNSPPLGMDELRTELVNMANDVSTCKGSSLALSELLSWVRGNGIRISQLLSSNEQFSQQRLPQKLSQVLHVCLETDNHIYSTISDYE
Involved as a receptor for mab-20/sema-2a in the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis . In early embryonic development, required for proper ventral closure of the epidermis . During male tail morphogenesis, involved in precursor cell sorting and in the formation of distinct sensory rays . Involved in axon guidance of SDQL neurons during neurogenesis . Probably in response to stimulation by mab-20, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus axon guidance and/or fasciculation of DD/VD neurons .
O45657
Q6AZW1
KISHB_DANRE
Transmembrane protein 167B
Danio
MTNVYSFDGILVFGLLFICTCAYLKKVPRLNSWLLSEKKGVWGVFYKAAVIGTRLHVVVAASCLCMAFYLIFLK
Involved in the early part of the secretory pathway.
Q6AZW1
B7H3S1
RUVC_ACIB3
Holliday junction resolvase RuvC
Acinetobacter calcoaceticus/baumannii complex
MPLIIGIDPGSRLTGYGIIEKDGSKLRFVDAGTIRTETQEMPERLKRIFAGVERIVKFHGPTEAAVEQVFMAQNPDSALKLGQARGAAIAALVNLDLQVAEYTARQIKQSVVGYGAADKEQVQMMVMRLLNLTIKPQADAADALAAAICHAHASGSMSKLTVLNALGGMARGRSRSSSRRR
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
B7H3S1
Q8VL14
KAIB_RIPO1
Circadian clock protein KaiB
Rippkaea orientalis
MVNFKKTYVLKLYVAGNTPNSVRALKTLKNILEDEFKGVYALKVIDVLKNPQLAEEDKILATPTLSKILPPPVRKIIGDLSDREKVLIGLDLLYEEIRERESEL
Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC.
Q8VL14
P46205
CCMO_SYNE7
ORF II
Synechococcus
MSASLPAYSQPRNAGALGVICTRSFPAVVGTADMMLKSADVTLIGYEKTGSGFCTAIIRGGYADIKLALEAGVATARQFEQYVSSTILPRPQGNLEAVLPISRRLSQEAMATRSHQNVGAIGLIETNGFPALVGAADAMLKSANVKLICYEKTGSGLCTAIVQGTVSNVTVAVEAGMYAAERIGQLNAIMVIPRPLDDLMDSLPEPQSDSEAAQPLQLPLRVREKQPLLELPELERQPIAIEAPRLLAEERQSALELAQETPLAEPLELPNPRDDQ
Beta-carboxysome assembly initiates when soluble RuBisCO is condensed into a liquid matrix in a pre-carboxysome by the RbcS-like domains of probably both CcmM58 and CcmM35. CcmN interacts with the N-terminus of CcmM58, and then recruits the CcmK2 major shell protein via CcmN's encapsulation peptide. Shell formation requires CcmK proteins and CcmO. CcmL caps the otherwise elongated carboxysome. Once fully encapsulated carboxysomes are formed, they migrate within the cell probably via interactions with the cytoskeleton.
P46205
Q2JHK3
NU1C_SYNJB
NDH-A
unclassified Synechococcus
MTNAGIDLQLGFETALQNLGLGAGAAHALWMPLPMLLLIIAATLGVMVMTWLERKISAAAQQRIGPNMAGPQGVLIPIADGIKLLTKEDVLPILADPVLFTLGPILVFLPVFLCYLVVPFGQNLLISNIAIGVFFLIAISSVQPIGLLMSGYGSNNKYSLLGGLRAAAQSISYELPLALSVLAVVLMSNGLDTVGIVEQQSGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEEELVAGYQTEYSGMKFALFYLGSYANLLLASLIAAVLYLGGWSFVVPVETIAALAGIPLDNPFLQIGAAALGIVMTMVKAFIFIFLAILLRWTLPRVRIDQLLDLGWKFLLPVSFVNLLLTAALKLAFPTFFGG
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Q2JHK3
Q087L5
LIPA_SHEFN
Sulfur insertion protein LipA
Shewanella
MNRPERLQPGVKLRDADKVARIPVKVVPSERETMLRKPDWLRVKLPSSNQRILEIKAALRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPLKADADEPKKLAQTIKDMKLKYVVITSVDRDDLRDGGAQHFADCIREIRLLNPEIKIETLVPDFRGRIDAALDILATEPPDVFNHNLETAPAHYRKARPGANYQWSLDLLKRFKERHPTIPTKSGLMMGLGETNEEIAEVLRDLRAHNVEMLTLGQYLQPSKFHLPVERYVPPAEFDELKALADELGFTHAACGPLVRSSYHADLQAQGKEVK
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
Q087L5
Q9UUG9
TSC2_SCHPO
Tuberous sclerosis 2 protein homolog
Schizosaccharomyces
MNNKSLLDLSSEPAIKDTDILSYFDANLPFKKRHQIVRSIYHGLKYYIYSSTSIIQVWQNIQDFISTKNDNAAFRELVYNLMMRYVSTQKHLSIIERHTFFQTIEKDPFQDIAELQLRLKSLSVLTDEGHKISGIENRVGPLLSAWFNQYLQWQSQATELQGKDADSKLVHLLFFKSLFKFSTNLVKFQWFLVPEPQMLQLVNSVVQICNHARLEDVVTEVLMFFDSMIRYSVIPKASLYDTVLILCSTYISTYSYSKLAQSVIFNLISSPVSNLAFENVFNILQYNRSNVNAVRGAVRLMRFLMLQEVKNDAIASITLSSSIEFTEFPLGFNENVDFEILGTVYLFLRTPSILNRLNFLDWHRILNILMYCSQYLPLKASTSKEAFSKTAAFANIYDRVLDFLDFEALIPLLQQFQVKLVFFLKDVLPVLKPKIRKKLLRLFETYNLIFPCNQYWVFNLEFLLGIYQCKTFDLEDRALLFKLVEDACSVADENSAPILCSKFLFPVIESFSKESDDCVVSPVYNMLFFLSVNFQNPGLKDCIDHIFQQLISDTSSVTVRRLATSTLIRLFYYYYDLRDAVPIQETLAKMLEILETPSFPFVSRMLCLQFFLRFRANGTSIYICENIDLNEPFKVLNVDSELIPAVYPISDSFVNSATVEKHIWERKENDLIKISNHSTEYGKDFVTFPTSSLLRFYRKSMATESNWTILMFMITHLADQISNRSMFIGALEEIYNLLDFMCDIVFERVSISAEIPSNIRKANIMIPILQNVQMLFVYHDQFSRAQEDELVSVFFAGLQKWNEACHVSIHSLMLCCYELPVSIRKQLPAILVTLSRLITKPDLSVHILEFLCSLARLPDLIANFTDADYRQIFAIALKYIQHRDFTKESKDSNDTESILKNSYSSYVLALAYSVLQIWFLSLRLTERKKFVPWILRGLKLASEGKPLEDLCLVQYDMMQQFCYSNSDINNQTSTFVDSDVESETWIRGNSLFTINVSVNSGFLEAVIRRPTGTTQYTFRNEASLQKFLWEENLTSSKALTRGLLCTPSSFVSHFLDPHGISLYNQPLLLPSNDDSVRRAISVFDRIPVIESLKAGLVYVGYQQRREADILANTNPSEDFLTFLNGLGTLFELKTDQKVFAGGLDRENDIDGAFAYCWKDKVTQMVFHCTTMMPTNIEHDPGCTLKKRHIGNDFVTIIFNESGLEYDFDTIPSQFNFVNIVITPESESIRRTGRQIKFYKVKALTKYDIDFSLFRRYKIVSSDALPAIVRDVTLNAAVFSHIYHRSAGDYVHIWAERLRQLKRLREKFQASVLPEDYNLDEQTKTKLQNGTNFSDFTSYL
Together with tsc1, required for uptake of various amino acids from the environment and for proper conjugation. Involved in induction of gene expression of permeases and genes required for meiosis upon nitrogen starvation. May act as a GTPase-activating protein (GAP) for the small GTPase rhb1.
Q9UUG9
Q969S2
NEIL2_HUMAN
Nei-like protein 2
Homo
MPEGPLVRKFHHLVSPFVGQQVVKTGGSSKKLQPASLQSLWLQDTQVHGKKLFLRFDLDEEMGPPGSSPTPEPPQKEVQKEGAADPKQVGEPSGQKTLDGSSRSAELVPQGEDDSEYLERDAPAGDAGRWLRVSFGLFGSVWVNDFSRAKKANKRGDWRDPSPRLVLHFGGGGFLAFYNCQLSWSSSPVVTPTCDILSEKFHRGQALEALGQAQPVCYTLLDQRYFSGLGNIIKNEALYRAGIHPLSLGSVLSASRREVLVDHVVEFSTAWLQGKFQGRPQHTQVYQKEQCPAGHQVMKEAFGPEDGLQRLTWWCPQCQPQLSEEPEQCQFS
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
Q969S2
O13849
CBPY_SCHPO
Carboxypeptidase Y
Schizosaccharomyces
MLMKQTFLYFLLTCVVSAQFNGYVPPEQNGGDIVVPKDFYEKFGEDFIREQEESSAPLMNPVPERDEAEAPHHPKGHHEFNDDFEDDTALEHPGFKDKLDSFLQPARDFLHTVSDRLDNIFDDDEDEHVREKRPHDSADEDAPRRKHGKCKGKGKHHKGKHAKGKGKKSHPKPEDDSVFFDDERPKHHEFDDEDREFPAHHEPGEHMPPPPMHHKPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPMHHEPGEHMPPPPFKHHELEEHEGPEHHRGPEDKEHHKGPKDKEHHKGPKDKEHHKGPKDKEHHKGPKDKEHHKGPKDKEHHKGPKDKEHHQGPKEKHNERPEQNMQSSHELLVIEAFADLINSVPVEEIAEEFSRFLDTLGIEYYGNIPVHIQENAPKDSSIPPLFEFDDDLELSDLTPEQFAYLEMLKAEGIDPMTAFRDQSHPAKPSNAQPADSSRPYAVFSQEENGEHVNLKAFPDHTLRVKDSKPESLGIDTVKQYTGYLDVEDDRHLFFWFFESRNDPENDPVVLWLNGGPGCSSLTGLFMELGPSSINIETLKPEYNPHSWNSNASVIFLDQPINTGFSNGDDSVLDTVTAGKDVYAFLNLFFAKFPQYAHLDFHIAGESYAGHYIPQFAKEIMEHNQGANFFVASGYEMEKQYINLKSVLIGNGLTDPLVQYYFYGKMACESPYGPIMSQEECDRITGAYDTCAKLITGCYQTGFTPVCIGASLYCNNAMIGPFTKTGLNIYDIREECRDQEHLCYPETGAIESYLNQEFVQEALGVEYDYKGCNTEVNIGFLFKGDWMRKTFRDDVTAILEAGLPVLIYAGDADYICNYMGNEAWTDALEWAGQREFYEAELKPWSPNGKEAGRGKSFKNFGYLRLYEAGHMVPFNQPEASLEMLNSWIDGSLFA
Involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate.
O13849
Q6JDS8
CYB_NEOJL
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Blanfordimys
MTNIRKKHPLIKIINHSFIDLPAPSNISSWWNFGSLLGLCLIIQILTGLFLAMHYTSDTATAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGVYYGSYNMIETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDFLGVLILLMVSMILTLFFPDVLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPLLHTSKQRALTFRPITQTMYWILVADLFILTWIGGQPVEYPFIIIGQAASIAYFTIIVILMPIAGMIENNIMDLD
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Q6JDS8
Q4ZVC2
AROC_PSEU2
5-enolpyruvylshikimate-3-phosphate phospholyase
Pseudomonas syringae
MSGNTFGKLFTVTTAGESHGPALVAIVDGCPPGLELDLQDLQRDLDRRKPGTSRHTTQRQEADEVEILSGVFEGKTTGASIGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLASQGIVIRGYMSQLGPIQIPFKTWDSVEDNAFFCPDPDKVPELEAYMDQLRRDQDSVGAKITVVADGVMPGLGEPIFDRLDAELAHALMSINAVKGVEIGAGFDCVAQRGTEHRDEMTPQGFLSNHAGGILGGISSGQPIIAHLALKPTSSITTPGRSIDVDGNAADVITKGRHDPCVGIRATPIAEAMMAIVLLDHLLRHRGQNADVSVNTPVLGQV
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
Q4ZVC2
Q45715
CR1KA_BACTM
Insecticidal delta-endotoxin CryIK(a)
Bacillus cereus group
MNSNRKNENEIINALSIPAVSNHSAQMDLSPDARIEDSLCVAEGNNIDPFVSASTVQTGISIAGRILGVLGVPFAGQLASFYSFLVGELWPSGRDPWEIFMEHVEQIVRQQQITDSVRDTAIARLEGLGRGYRSYQQALETWLDNRNDARSRSIIRERYIALELDITTAIPLFSIRNEEVPLLMVYAQAANLHLLLLRDASLFGSEWGMSSADVNQYYQEQIRYTEEYSNHCVQWYNTGLNRLRGTTAETWVRYNQFRRDLTLGVLDLVALFPSYDTRTYPIPTTAQLTREVYTDPNGVVAGPNNSWFRNGASFSAIENAIIRQPHLYDFLTNLTIYTRRSQVGTTIMNLWAGHRITFNRIQGGSTSEMVYGAITNPVSVSDIPFVNRDVYRTVSLAGGLGSLSGIRYGLTRVDFDMIFRNHPDIVTGLFYHPGHAGIATQVKDSDTELPPETTEQPNYRAFSHLLSHISMGPTTQDVPPVYSWTHQSADRTNTINSDRITQIPLVKAHTLQSGTTVVKGPGFTGGDILRRTSGGPFAFSNVNLDFNLSQRYRARIRYASTTNLRIYVTVAGERIFAGQFDKTMDAGAPLTFQSFSYATINTAFTFPERSSSLTIGADTFSSGNEVYVDRFELIQVTATFEAESDLERARKAVNALFTSTNPRGLKTDVTDYHIDQVSNLVECLSDEFCLDKKRELLEEVKYAKRLSDERNLLQDPTFTSISGQTDRGWIGSTGISIQGGDDIFKENYVRLPGTVDECYPTYLYQKIDESQLKSYTRYQLRGYIEDSQDLEIYLIRYNAKHETLSVPGTESPWPSSGVYPSGRCGEPNRCAPRIEWNPDLDCSCRYGEKCVHHSHHFSLDIDVGCTDLNEDLGVWVIFKIKTQDGHAKLGNLEFIEEKPLLGKALSRVKRAEKKWRDKYEKLQLETKRVYTEAKESVDALFVDSQYDKLQANTNIGIIHGADKQVHRIREPYLSELPVIPSINAAIFEELEGHIFKAYSLYDARNVIKNGDFNNGLSCWNVKGHVDVQQNHHRSVLVLSEWEAEVSQKVRVCPDRGYILRVTAYKEGYGEGCVTIHEFEDNTDVLKFRNFVEEEVYPNNTVTCNDYTTNQSAEGSTDACNSYNRGYEDGYENRYEPNPSAPVNYTPTYEEGMYTDTQGYNHCVSDRGYRNHTPLPAGYVTLELEYFPETEQVWIEIGETEGTFIVGSVELLLMEE
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects. Selectively toxic to Artogeia rapae but not active on Plutella xylostella.
Q45715
Q5HZ38
GRIK2_ARATH
SnRK1-activating protein kinase 1
Arabidopsis
MFRDSFLFARTIGCFGCFGSSGSRNQQSPKPYDDDTHSCDSDVTSTARGEEEEDEEEVEQKSRSKRSEEILKYRLDNGLICRHIPVRETNELIRGEDENGDKTINEYVRVCKIGSGSYGKVVLYRSTLDGQYYAIKAFHKSHLLRLRVAPSETAMSDVLREVMIMKILEHPNIVNLIEVIDDPETDHFYMVLEYVDGKWVYDGSGPPGALGEKTARKYLRDIVTGLMYLHAHDVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFTAPECCLVSGITYSGRAADTWAVGVTLYCMILGQYPFLADTLQDTYDKIVNNPLIIPDGLNPLLRDLIEGLLCKDPSQRMTLKNVSEHPWVIGEDGHVPEYFCWCKRNAASKIEEGEANGISETSDPN
Activates SnRK1.1/KIN10 and SnRK1.2/KIN11 by phosphorylation of their activation-loop 'Thr-198' and 'Thr-176', respectively. Required for the regulation by SnRK1 kinases of the transcription of a large set of genes, the modification the activity of metabolic enzymes, and the control of various nutrient-responsive cellular developmental processes.
Q5HZ38
Q1Q893
ATP6_PSYCK
F-ATPase subunit 6
Psychrobacter
MAGEQTTTEYISHHLTNWTYGYLPGEGWKVAYNAEEASAMGFKAIHLDSMLWSIGLGIVFCAIFWMVARKVTSGVPGKTQAAVEMIVEFVDNNVRDSYSGTSKLIAPLALTIFVWIFLMNLMDLLPVDFIPMIAGQIGALMGHDPHHVYFKIVPTTDPNITLGMSFSVFILILFYSIKEKGLGGFVGELTLHPFSAKNPIVQIILIPINFILEFVTLIAKPISLGLRLFGNMYAGELIFILIALMPFWIQWALSVPWAIFHILIITLQAFVFMMLTIVYMSLASSTEH
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
Q1Q893