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Given the on-going challenges faced by the National Health Service (NHS) in the United Kingdom, such as long waiting times, staff shortages, increased demand for services because of the COVID-19 pandemic, there is an urgent need to develop new ways to support those living with chronic breathlessness. One potential solu... |
With the help of patients and NIHR funding the research team lead by Dr Charles Reilly, developed an online breathlessness supportive website called SELF-BREATHE. SELF-BREATHE provides information and self-management tools such as breathing exercises, that patients can do at home themselves. |
SELF-BREATHE has been tested as part of its development. SELF-BREATHE is acceptable and valued by patients. But what is unknown is whether SELF-BREATHE improves patients' breathlessness and their life? This is the question this research seeks to answer. |
Aims |
1. To test if using SELF-BREATHE for six-weeks improves patients' breathlessness, their quality of life and whether SELF-BREATHE should be offered within the NHS |
2. To see if patients opt to continue to use SELF-BREATHE after six-weeks and what benefits this may have for patients. |
Methods |
The research team are undertaking a randomised controlled trial. For this, 246 people living with chronic breathlessness will be recruited in to this study. Each person will be randomly chosen by a computer to continue with their usual care or their usual care plus access to SELF-BREATHE. All study participants will co... |
These questionnaires will ask patients about 1) their breathlessness and its effect on their life and 2) planned and unplanned hospital visits. At the end of the study, we will compare answers to these questionnaires between the two groups at seven and 12 weeks. |
This will tell if SELF-BREATHE improved patients' breathlessness and reduced their need for unplanned hospital visits e.g., A\&E attendances due to breathlessness. conditions: Chronic Obstructive Pulmonary Disease conditions: Bronchiectasis conditions: Interstitial Lung Disease conditions: Lung Cancer conditions: Asthm... |
<|newrecord|> nctId: NCT06326944 id: MS-527-2023 briefTitle: Fascia Transversalis Versus Transversus Abdominis Plane Block for Children Undergoing Inguinal Hernia Surgery overallStatus: RECRUITING date: 2024-01-18 date: 2024-04 date: 2024-05 date: 2024-03-22 date: 2024-03-22 name: Kasr El Aini Hospital class: OTHER bri... |
<|newrecord|> nctId: NCT06326931 id: JE001 briefTitle: Thermal Pulsation Versus Warm Compress Treatment for Meibomian Gland Dysfunction overallStatus: COMPLETED date: 2022-06-24 date: 2023-06-22 date: 2023-06-22 date: 2024-03-22 date: 2024-03-22 name: Jacksoneye class: OTHER briefSummary: This study aimed to assess the... |
<|newrecord|> nctId: NCT06326918 id: RP026 briefTitle: Duodenal Microbiota in Functional Dyspepsia overallStatus: RECRUITING date: 2024-02-12 date: 2024-12-31 date: 2025-06-30 date: 2024-03-22 date: 2024-03-22 name: King Chulalongkorn Memorial Hospital class: OTHER briefSummary: The goal of this observational study is ... |
* What are the differences in the type of duodenal microbiota and is there a difference in duodenal microbiome diversity between patients diagnosed with functional dyspepsia (FD) and the control group? |
* Are there any significant variations in the composition and diversity of gut microbiota between patients with FD and the control group, considering the method of sample collection (duodenal brushing vs. duodenal biopsy)? conditions: Functional Dyspepsia studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePe... |
<|newrecord|> nctId: NCT06326905 id: IRB00437750 id: K23DK133677-01A1 type: NIH link: https://reporter.nih.gov/quickSearch/K23DK133677-01A1 briefTitle: CAPABLE Transplant overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-09-01 date: 2026-05-01 date: 2024-03-22 date: 2024-03-22 name: Johns Hopkins University... |
<|newrecord|> nctId: NCT06326892 id: CHR1-101-2024 briefTitle: Natural Orifice Specimen Extraction in Low Rectal Cancer Surgery acronym: NOSES overallStatus: RECRUITING date: 2023-07-31 date: 2024-04-30 date: 2024-10-15 date: 2024-03-22 date: 2024-03-25 name: Istituto Clinico Humanitas class: OTHER briefSummary: This s... |
<|newrecord|> nctId: NCT06326879 id: 3527 briefTitle: A Comparative Study Between Early Onset Colorectal Cancer and Late Onset Colorectal Cancer Patients acronym: EOrOS overallStatus: RECRUITING date: 2023-11-30 date: 2026-12-31 date: 2027-10-30 date: 2024-03-22 date: 2024-03-25 name: Istituto Clinico Humanitas class: ... |
<|newrecord|> nctId: NCT06326866 id: E-74555795-050.04-941208 briefTitle: Otoacoustic Emissions in Different Blood Types overallStatus: COMPLETED date: 2024-02-07 date: 2024-03-12 date: 2024-03-18 date: 2024-03-22 date: 2024-03-26 name: Istanbul University - Cerrahpasa (IUC) class: OTHER briefSummary: The objective of ... |
<|newrecord|> nctId: NCT06326853 id: Adipofisi briefTitle: Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical Models overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-03 date: 2026-12 date: 2024-03... |
<|newrecord|> nctId: NCT06326840 id: 98107 briefTitle: Clinical Efficacy and Adverse Reactions of Antipsychotic Treatment overallStatus: COMPLETED date: 2010-05-31 date: 2011-06-10 date: 2011-06-10 date: 2024-03-22 date: 2024-03-22 name: Taipei Medical University Hospital class: OTHER name: Taipei Medical University br... |
1. The effect of metformin on olanzapine-induced metabolic disturbance |
2. The effect of metformin on olanzapine-induced hyperprolactinemia |
Participants will receive metformin 1500 mg/day for 8 weeks and assessments every 2 weeks. conditions: Metabolic Disturbance conditions: Hyperprolactinemia conditions: Schizophrenia studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 42 type... |
<|newrecord|> nctId: NCT06326827 id: P231127IBSORTHO briefTitle: In'Oss™ (MBCP® Putty) Ortho overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-05 date: 2026-08 date: 2024-03-22 date: 2024-03-29 name: Advanced Medical Solutions Ltd. class: INDUSTRY briefSummary: Study of the osteoconductive potential of the inj... |
<|newrecord|> nctId: NCT06326814 id: TDU16837 id: U1111-1298-7281 type: REGISTRY domain: ICTRP briefTitle: A Study to Test if SAR443809 is Tolerated and Safe When Taken as a Single Dose in Healthy Adults overallStatus: COMPLETED date: 2021-10-11 date: 2023-05-05 date: 2023-05-05 date: 2024-03-22 date: 2024-03-22 name: ... |
* The tolerability and safety of SAR443809 Secondary |
* The PK parameters of SAR443809 |
* The PD activity of SAR443809 |
* The immunogenicity of SAR443809 conditions: Paroxysmal Nocturnal Hemoglobinuria studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 54 type: ACTUAL name: Humanized anti-Factor Bb m... |
<|newrecord|> nctId: NCT06326801 id: REC/014220 Muhammad Iqbal briefTitle: Resistive Diaphragmatic Breathing Exercise With Pursed Lips Breathing Exercise in Sub-acute Stroke Patients overallStatus: COMPLETED date: 2023-09-01 date: 2024-01-15 date: 2024-01-18 date: 2024-03-22 date: 2024-03-22 name: Riphah International ... |
<|newrecord|> nctId: NCT06326788 id: 3912 Mehnoor Butt briefTitle: Effects of Moderate Intensity Soleus Push-ups vs Sustained Soleus Push-ups on Lipid Profile Among Young Population overallStatus: RECRUITING date: 2023-10-01 date: 2024-07-28 date: 2024-07-30 date: 2024-03-22 date: 2024-03-22 name: Riphah International ... |
<|newrecord|> nctId: NCT06326775 id: KY20240311-KS-02 briefTitle: Research on Precision Pharmaceutical Care for Heart Transplant Recipients overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-12 date: 2026-12 date: 2026-12 date: 2024-03-22 date: 2024-03-22 name: Nanjing First Hospital, Nanjing Medical University class: ... |
<|newrecord|> nctId: NCT06326762 id: younes briefTitle: Gap CO2 in Septic Patient to Predict Cardiomyopathy Septic overallStatus: COMPLETED date: 2023-01-01 date: 2023-10-30 date: 2023-10-30 date: 2024-03-22 date: 2024-03-22 name: Mohammed VI University Hospital class: OTHER briefSummary: the investigators included 98 ... |
Subsequently. the investigators examined the clinical and paraclinical profile of patients with septic cardiomyopathy. the investigators identified 19 patients with this condition, while 79 patients did not exhibit cardiac involvement. The percentage was significantly higher in the population with cardiac involvement, ... |
<|newrecord|> nctId: NCT06326749 id: 2024/19 briefTitle: Effectiveness of Modified Graded Motor Imagery Training in Stroke Patients overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-11-15 date: 2025-03-15 date: 2024-03-22 date: 2024-03-22 name: Inonu University class: OTHER briefSummary: In the study, movem... |
<|newrecord|> nctId: NCT06326736 id: 2024NZKY-014-02 briefTitle: Study of Neoantigen mRNA Vaccines in Patients With Resectable Pancreatic Cancer overallStatus: RECRUITING date: 2024-04 date: 2025-12 date: 2026-12 date: 2024-03-22 date: 2024-03-22 name: Jinling Hospital, China class: OTHER name: Jiangsu Synthgene Biotec... |
<|newrecord|> nctId: NCT06326723 id: SIM0808-101 briefTitle: Investigate the PK, Safety, and Tolerability After Single and Multiple Dose Daridorexant in Chinese Healthy Subjects overallStatus: COMPLETED date: 2023-09-04 date: 2023-12-24 date: 2024-02-05 date: 2024-03-22 date: 2024-03-22 name: Jiangsu Simcere Pharmaceut... |
<|newrecord|> nctId: NCT06326710 id: P0045122 briefTitle: The 'Outdoor Rehab-Fit' App-based Physical Activity Education Intervention for Frail Older Adults in Hong Kong overallStatus: RECRUITING date: 2024-04-01 date: 2024-10-01 date: 2024-12-31 date: 2024-03-22 date: 2024-04-09 name: The Hong Kong Polytechnic Universi... |
A recent local in-depth qualitative study discovered that OEFs in Hong Kong attracted frailer older adults (i.e., those who recovered from a major illness or who has chronic diseases), and their caregivers to use OEFs to support and maintain their daily PA behavior. Some used OEFs to complement their formal rehabilitat... |
A mobile app-based physical activity education intervention will be developed for frail old adults in Hong Kong. The intervention has two components: (1) mobile app; and (2) face-to-face group session that teaches the how to use correctly and safely use OEF in public parks to maintain PA habits. |
The main objective of this study is to evaluate the feasibility, acceptability, and pilot effectiveness of the 'Outdoor Rehab-Fit' App-based physical activity education intervention. Primary outcomes include recruitment rate, retention rate, attrition rate, attendance, perceived usefulness of the app. Secondary outcome... |
This study adopts a mixed-method design with quantitative and qualitative method. This study is a pilot randomized controlled trial, running for 4 months evaluating of the effectiveness of the mHealth intervention. 40 frail older adults will be randomized into (i) mHealth group or (ii) control group. |
Quantitative analysis will be adopted to investigate the effectiveness of the 'Outdoor Rehab-Fit' App-based physical activity education intervention on the health outcomes of frail older adults. The qualitative component will consist of semi-structure interviews with the frail older adults to understand the acceptabili... |
<|newrecord|> nctId: NCT06326697 id: HIK-AZA-2023-01 briefTitle: Bioequivalence of Azacitidine 300 mg Film-Coated Tablets in Adult Patients With Acute Myeloid Leukaemia (AML) overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-01 date: 2025-03 date: 2024-03-22 date: 2024-03-22 name: Hikma Pharmaceuticals LLC cla... |
<|newrecord|> nctId: NCT06326684 id: 88524 briefTitle: Suvorexant and Alcohol overallStatus: NOT_YET_RECRUITING date: 2024-06-15 date: 2027-03-15 date: 2027-03-15 date: 2024-03-22 date: 2024-03-27 name: University of Kentucky class: OTHER name: National Institute on Alcohol Abuse and Alcoholism (NIAAA) briefSummary: Th... |
<|newrecord|> nctId: NCT06326671 id: STXA-BE-03 briefTitle: A Trial to Assess the Bioequivalence of Generic Tiotropium Bromide Inhalation Powder and Reference Product in Healthy Adult Participants Under Fasting Conditions (Pilot) overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-28 date: 2024-03 date: 2024-04 date: 20... |
<|newrecord|> nctId: NCT06326658 id: TCM for Frequent AECOPD briefTitle: Bufei Yishen Prescription on Patients With Frequent AECOPD in Stable Stage overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-05-01 date: 2026-10-31 date: 2024-03-22 date: 2024-03-22 name: Henan University of Traditional Chinese Medicin... |
<|newrecord|> nctId: NCT06326645 id: IRB23-891 briefTitle: Open-Label Pilot Study With Crofelemer in Patients With Short Bowel Syndrome overallStatus: NOT_YET_RECRUITING date: 2024-12-01 date: 2025-12-01 date: 2025-12-01 date: 2024-03-22 date: 2024-03-22 name: Lindsey Russell, MD class: OTHER name: Napo Pharmaceuticals... |
<|newrecord|> nctId: NCT06326632 id: RHPT/0022/023 briefTitle: Comparative Effectiveness Study of Constant-Load Versus Graded Aerobic Exercise in Obese Children With Bronchial Asthma overallStatus: COMPLETED date: 2022-10-30 date: 2023-12-07 date: 2023-12-07 date: 2024-03-22 date: 2024-03-22 name: Cairo University clas... |
A total of 78 children with BA were randomly assigned to the CL-AE group (n = 26, who underwent moderate-intensity aerobic training with the training load maintained at the same level throughout the entire program, besides the respiratory re-training program), the G-AE group (n = 26, received an intensity- and duration... |
The cardiopulmonary fitness and functional capacity were evaluated in the three groups before and after the completion of the assigned interventions. conditions: Bronchial Asthma studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A prospective, three-ar... |
<|newrecord|> nctId: NCT06326619 id: SurvSysT briefTitle: Survival Benefit of Primary Tumour Resection Compared to Systemic Therapy Alone in Stage IV Colorectal Cancer Patients acronym: SurvSysT overallStatus: COMPLETED date: 2012-01-01 date: 2020-12-31 date: 2020-12-31 date: 2024-03-22 date: 2024-03-22 name: Medizinis... |
The objective of the present study is to compare the survival of palliative stage IV colorectal cancer patients selected for primary tumor resection and systemic treatment (PTR+SYST) to patients with systemic treatment only (SYST). conditions: Colorectal Cancer conditions: Neoadjuvant Systemic Therapy studyType: OBSERV... |
<|newrecord|> nctId: NCT06326606 id: 23-MLS101-101 briefTitle: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MLS101 in Healthy Participants overallStatus: RECRUITING date: 2024-03 date: 2024-09 date: 2024-10 date: 2024-03-22 date: 2024-03-22 name: MycoMedica Life Sciences PBC class: INDUSTRY bri... |
The purpose of this clinical trial is to assess how safe and tolerated MLS101 is; to see how MLS101 is distributed and cleared by the body (pharmacokinetics); and to assess the psychedelic effects of MLS101 in healthy adult participants. conditions: Healthy Volunteers studyType: INTERVENTIONAL phases: PHASE1 allocation... |
Part 1 - Single Ascending Dose (SAD): 24 participants will be enrolled in 3 sequential dose cohorts and will be randomized to receive a single dose of MLS101 or placebo. Additional cohorts (comprising 8 participants in each cohort) may be enrolled to explore more doses. |
Part 2: Multiple Dose study, doses and administration regimens are pending the results from Part 1 primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: Psilocybin name: Placebo measure: Incidence... |
<|newrecord|> nctId: NCT06326593 id: P.T.REC/012/005049 briefTitle: Wii Aerobic Training in Inhalation-injury Children Post-thermal Burn overallStatus: RECRUITING date: 2024-02-22 date: 2024-05-25 date: 2024-06-01 date: 2024-03-22 date: 2024-03-22 name: MTI University class: OTHER briefSummary: Inhalation injury is a c... |
Wii fit aerobic training gives similar results with traditional rehabilitation practices, it causes less energy costs. This suggests that it can be a suitable rehabilitation tool for adult and elderly people with low energy levels. A review showed that video games are safe and feasible in the children with lung complic... |
<|newrecord|> nctId: NCT06326580 id: MS.22.09.2144 briefTitle: Clinical Prediction Model of Obstructive Sleep Apnea at Mansoura University Hospitals overallStatus: COMPLETED date: 2022-10-20 date: 2023-10-20 date: 2024-02-20 date: 2024-03-22 date: 2024-03-22 name: Mansoura University class: OTHER briefSummary: Obstruct... |
Obstructive sleep apnea it is increasingly recognized as an independent risk factor for cardiac, neurologic, and perioperative morbidities. Yet this disorder remains undiagnosed in a substantial portion of our population. It is imperative for all physicians to remain vigilant in identifying patients with signs and symp... |
The test of hypothesis is to design a clinical prediction model of obstructive sleep apnea from collected data of the patients having symptoms of obstructive sleep apnea and the results of their sleep study conditions: Osa Syndrome studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: OTHER count: 1129 ty... |
<|newrecord|> nctId: NCT06326567 id: 84032 briefTitle: Comprehensive Connected Cancer Care (C4): Intervention Evaluation overallStatus: RECRUITING date: 2024-02-01 date: 2025-06 date: 2025-06 date: 2024-03-22 date: 2024-03-22 name: Timothy Mullett class: OTHER name: Merck Sharp & Dohme LLC briefSummary: The C4 program ... |
<|newrecord|> nctId: NCT06326554 id: 22-5933 briefTitle: Single Arm Pilot Trial of Virtual and In-person STEP2 acronym: STEP2 overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-01-01 date: 2025-01-01 date: 2024-03-22 date: 2024-03-22 name: University Health Network, Toronto class: OTHER briefSummary: The goa... |
Participants will be asked to complete questionnaires assessing quality of life, symptom burden, depression, anxiety, and satisfaction with care at baseline, 2, 4, and 6 months. conditions: Oncology studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Single ... |
<|newrecord|> nctId: NCT06326541 id: okutan briefTitle: The Effect of Listening to the Holy Quran on Vital Signs in Coma Patients overallStatus: COMPLETED date: 2023-01-05 date: 2023-12-10 date: 2023-12-30 date: 2024-03-22 date: 2024-03-22 name: Bitlis Eren University class: OTHER briefSummary: The aim of this study is... |
Does listening to the Holy Quran have a positive effect on the life values of coma patients? conditions: Sequelae of; Complications Surgical and Medical Care studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: single group pretest-posttest primaryPurpose: SU... |
<|newrecord|> nctId: NCT06326528 id: SGLT2 inhibitors briefTitle: SGLT2 Inhibitors and Perioperative Period overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-04-01 date: 2025-10-01 date: 2024-03-22 date: 2024-03-22 name: Assiut University class: OTHER briefSummary: The expanded use of SGLT2 inhibitors motiv... |
<|newrecord|> nctId: NCT06326515 id: Government College University briefTitle: Cognitive Behavior Therapy for Depression, Stigmatization, Criminogenic Cognition, and Quality of Life Among Patients With Opioid Use Disorder (OUD): A Randomized Control Trial. acronym: CBT with OUD overallStatus: ACTIVE_NOT_RECRUITING date... |
In this randomize control trail (RCT), N=120 patients with relapse condition would be taken. After enrolment patients' eligibility assessment would be completed and then n=60 patients would be allocated to experimental (n=30) and waitlist control (n=30) through random assignment. Patient's age range would be between 20... |
<|newrecord|> nctId: NCT06326502 id: 22ETN101-2IND001 briefTitle: A Safety and Efficacy Study of Multiple Tyrosine Kinase Inhibitor Drug (ETN101) in Advanced Hepatocellular Carcinoma overallStatus: RECRUITING date: 2024-02-07 date: 2027-03-07 date: 2027-06-07 date: 2024-03-22 date: 2024-03-27 name: Etnova Therapeutics ... |
<|newrecord|> nctId: NCT06326489 id: 105122023-1/05.12.2023 id: ERP-2023-13520 type: OTHER_GRANT domain: Medtronic briefTitle: Evaluating the Efficacy and Quality of Life Impact of Transitioning to Advanced Hybrid Closed-Loop Insulin Pump Therapy in Romanian Children With Type 1 Diabetes Mellitus overallStatus: RECRUIT... |
Secondary Outcomes: changes in insulin requirements, time in range (TIR) levels, time below range (TBR), coefficient of variation (CV), frequency of severe hypoglycemic and hyperglycemic events requiring hospitalization, and PedsQL SF15 questionnaire scores. conditions: Diabetes Mellitus, Type 1 studyType: INTERVENTION... |
<|newrecord|> nctId: NCT06326476 id: IRB-300012699 id: 000544067 type: OTHER domain: University of Alabama at Birmingham briefTitle: A Study to Demonstrate the Safety and Efficacy of Siplizumab in the Treatment of Hidradenitis Suppurativa overallStatus: NOT_YET_RECRUITING date: 2025-01 date: 2025-09-30 date: 2025-12-31... |
<|newrecord|> nctId: NCT06326463 id: DIRECT70 id: NCI-2024-03240 type: OTHER domain: NCI Clinical Trial Registration Program briefTitle: CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2030-07-01 date: 2031-07-01 date: 2024... |
Primary Objective |
To determine the safety and maximum tolerated dose of intravenous infusions of escalating doses of CD70-CAR T cells in patients (≤21 years) with recurrent/refractory CD70+ hematological malignancies after lymphodepleting chemotherapy. |
Secondary Objectives |
To evaluate the antileukemic activity of CD70-CAR T cells. We will determine the anti- leukemic activity of the CD70-CAR T cells in the bone marrow and in the treatment of extramedullary disease. conditions: Hematologic Malignancy conditions: ALL, Childhood conditions: AML, Childhood conditions: Lymphoma conditions: MD... |
<|newrecord|> nctId: NCT06326450 id: 74626 briefTitle: Traditional In-Person Vs. Remote AR Clinical Simulation acronym: AR Brazil overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-05-31 date: 2025-05-31 date: 2024-03-22 date: 2024-04-12 name: Stanford University class: OTHER briefSummary: This is a non-infe... |
<|newrecord|> nctId: NCT06326437 id: 1223 briefTitle: Dyadic Intervention for Psychological Distress of Patients With Colorectal Cancer and Their Spouses overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-06-01 date: 2024-07-01 date: 2024-03-22 date: 2024-03-22 name: Sun Yat-sen University class: OTHER brief... |
<|newrecord|> nctId: NCT06326424 id: 2023H0085 briefTitle: Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department acronym: DELIRIUM overallStatus: NOT_YET_RECRUITING date: 2024-04-10 date: 2025-03-01 date: 2025-03-01 date: 2024-03-22 date: 2024-03-22 name: Ohi... |
Clinicians are bad at recognizing delirium. A recent systematic review led by the Geriatric Emergency Care Applied Research network (NIH funded) found that current delirium screening tools are at most 64% sensitive, meaning that physicians can identify some phenotypes of delirium well, but cannot easily rule out deliri... |
The investigators propose integrating wrist biosensors into the emergency management of older adults with dementia. The investigators will monitor heart rate variability, movement, and electrodermal activity (electrical activity of at the level of the skin) to determine if an array of biosensors more sensitive to delir... |
<|newrecord|> nctId: NCT06326411 id: NST-628-001 briefTitle: A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors acronym: NST-628 overallStatus: RECRUITING date: 2024-03 date: 2028-11 date: 2029-11 date: 2024-03-22 date: 2024-03-27 name: Nested Therapeutics, Inc class: I... |
<|newrecord|> nctId: NCT06326398 id: 3D moulage briefTitle: The Effect of Using 3D Printers and Moulage on Improving Stoma Care overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-05-01 date: 2024-10-01 date: 2024-03-22 date: 2024-03-25 name: Namik Kemal University class: OTHER name: TÜBİTAK briefSummary: Whe... |
<|newrecord|> nctId: NCT06326385 id: 53244021 briefTitle: Machine Learning Predictive Models for Sepsis Risk in ICU Patients With Intracerebral Hemorrhage overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2024-05-01 date: 2024-05-30 date: 2024-03-22 date: 2024-03-25 name: Xiangya Hospital of Central South Univer... |
The Medical Information Mart for Intensive Care (MIMIC) IV database (version 2.2) is an international online repository for critical care expertise. This database contains patient-related information collected from the ICUs of Beth Israel Deaconess Medical Center between 2008 and 2019. It includes a vast dataset of 299... |
The eICU Collaborative Research Database (eICU-CRD) comprises data from over 200,000 ICU admissions for 139,367 unique patients across 208 US hospitals between 2014 and 2015, providing a valuable resource for critical care research. |
This study aims to establish and validate multiple machine learning models to predict the onset of sepsis in ICU patients with ICH and to identify the model with the optimal predictive performance. conditions: Intracerebral Hemorrhage conditions: Sepsis studyType: OBSERVATIONAL observationalModel: COHORT timePerspectiv... |
<|newrecord|> nctId: NCT06326372 id: Delirium briefTitle: The Effect of Intraoperative Hyperoxemia on Postoperative Delirium in Geriatric Patients overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2024-06-20 date: 2024-07-01 date: 2024-03-22 date: 2024-03-28 name: Tepecik Training and Research Hospital class: OT... |
Oxygen reserve index (ORi™) (Masimo Corp., Irvine, USA) can guide clinicians in detection of hyperoxia. ORi is a parameter which can evaluate partial pressure of oxygen (PaO2) rating from 0 to 1. There are growing evidences in ORi that it might be helpful to reduce hyperoxia in general anesthesia. Continuous ORi monito... |
<|newrecord|> nctId: NCT06326359 id: Soh-Med-24-02-03MD briefTitle: Autologous Stromal Vascular Fraction in Treatment of Male Androgenic Alopecia overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-10 date: 2026-10 date: 2024-03-22 date: 2024-03-22 name: Sohag University class: OTHER briefSummary: Evaluation of ... |
<|newrecord|> nctId: NCT06326346 id: AMC2401 briefTitle: GIST Oral Paclitaxel(Liporaxel) overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2027-03-31 date: 2027-03-31 date: 2024-03-22 date: 2024-03-27 name: Asan Medical Center class: OTHER briefSummary: The purpose of this study is to evaluate safety and efficac... |
<|newrecord|> nctId: NCT06326333 id: E.Kurul-E2-24-6176 briefTitle: Combination of Parasternal and Serratus Anterior Plane Block in Coronary Artery Bypass Graft Surgery overallStatus: COMPLETED date: 2024-02-07 date: 2024-03-27 date: 2024-04-18 date: 2024-03-22 date: 2024-04-22 name: Ankara City Hospital Bilkent class:... |
In addition to intravenous medications, various neuraxial and peripheral nerve blocks can be used in cardiac surgery. In recent years, neuraxial anesthesia has been avoided due to the use of intraoperative high-dose heparin. As an alternative, peripheral nerve blocks have recently gained popularity. Parasternal block (... |
With this study, it was aimed to observe the analgesic effects on both the sternum and the drain site by applying PSB and SAPB applications simultaneously in the postoperative analgesia of CABG patients. conditions: Parasternal Block conditions: Serratus Anterior Plane Block conditions: Acute Pain conditions: Postopera... |
<|newrecord|> nctId: NCT06326320 id: E.Kurul-E2-24-6175 briefTitle: Combined SAPB in MICS overallStatus: RECRUITING date: 2024-02-07 date: 2024-05-07 date: 2024-05-17 date: 2024-03-22 date: 2024-03-25 name: Ankara City Hospital Bilkent class: OTHER briefSummary: Minimally invasive cardiac surgery (MICS) has begun to be... |
Postoperative analgesia is a critical risk factor for the development of pulmonary and cardiovascular complications in any type of cardiothoracic surgery. If patients with high pain levels cannot breathe effectively, it may lead to atelectasis, cardiac ischemia, and arrhythmias. This prolongs the time it takes for pati... |
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