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In addition to intravenous medications, various neuraxial and peripheral nerve blocks can be used in cardiac surgery. In recent years, thoracic epidural analgesia has been avoided due to the use of intraoperative high-dose heparin. As an alternative, peripheral nerve blocks have recently gained popularity. SAPB is one ...
In this study, the analgesic effects of ultrasound-guided CSAPB application in patients undergoing MICS will be evaluated. conditions: Serratus Anterior Plane Block conditions: Acute Pain conditions: Postoperative Analgesia conditions: Minimal Invasive Cardiac Surgery studyType: INTERVENTIONAL phases: NA allocation: NA...
<|newrecord|> nctId: NCT06326307 id: 247-05-21 briefTitle: Effectiveness of Puppet Modeling Technique on Children Undergoing Stressful Dental Procedures overallStatus: COMPLETED date: 2023-01-01 date: 2023-12-01 date: 2023-12-01 date: 2024-03-22 date: 2024-03-22 name: King Abdulaziz University class: OTHER briefSummary...
* The main question\[s\] it aims to answer are:
1. To compare the effect of puppet modeling vs tell show and do on the cooperation of children during the administration of local anesthesia.
2. To compare the effect of puppet modeling vs tell show and do on the anxiety level of children during the administration of local anesthesia.
type of study: clinical trial participant population/health conditions: Healthy
In this randomized crossover clinical trial, study subjects were randomly allocated into two groups:
* Group I : Children who received puppet behavior guidance during their first visit and tell-show-do guidance in their second visit, 2 weeks later. (P-TSD)
* Group II : Children who received the tell-show-do behavior guidance during their first visit and puppet behavioral guidance in their second visit, 2 weeks later.(TSD-P) conditions: Behavioral Guidance in Pediatric Dentistry studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER inter...
* Group II: Children who received the tell-show-do behavior guidance during their first visit and puppet behavioral guidance in their second visit, 2 weeks later.(TSD-P) primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Two evaluators, who are blinded to the experimented techniques, watched recorded videos ...
<|newrecord|> nctId: NCT06326294 id: 727/CNBS/23 briefTitle: Assessment of the Effectiveness of TA Versus LEEP for Cervical Cancer Risk Reduction in WLHIV in Mozambique overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-09 date: 2027-12 date: 2024-03-22 date: 2024-03-22 name: Instituto Nacional de Saúde, Mozamb...
<|newrecord|> nctId: NCT06326281 id: ACHBILKENT-ANEST-BK-01 briefTitle: Postoperative Pain Management in Laparoscopic Cholecystectomies overallStatus: COMPLETED date: 2023-07-01 date: 2024-02-22 date: 2024-02-28 date: 2024-03-22 date: 2024-03-22 name: Ankara City Hospital Bilkent class: OTHER briefSummary: This study i...
It aims to add new applications to multimodal analgesia methods, which provide the greatest contribution to the early recovery process after surgery, and to contribute to the early recovery process by increasing patient satisfaction. conditions: Cholecystitis/Cholelithiasis studyType: INTERVENTIONAL phases: NA allocati...
<|newrecord|> nctId: NCT06326268 id: 2023-019 id: 2023-A02133-42 type: OTHER domain: ID-RCB Number briefTitle: Interest of Light Therapy in Hematology - The PHOTO-TREAT Study acronym: PHOTO-TREAT overallStatus: RECRUITING date: 2024-04-17 date: 2025-09-17 date: 2025-09-17 date: 2024-03-22 date: 2024-04-22 name: Institu...
The only therapies currently offered are local care and intravenous analgesics. Studies in pediatric hematology show the effectiveness of prevention and low-dose laser treatment in chemo-induced mucositis, both in terms of reducing the number of mucositis developed but also in terms of reducing the grade of mucositis. ...
<|newrecord|> nctId: NCT06326255 id: LYASD briefTitle: Feasibility and Acceptability of Laughter Yoga in Children With Autism Spectrum Disorder and Their Parents overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2024-10-01 date: 2025-12-31 date: 2024-03-22 date: 2024-03-22 name: The Hong Kong Polytechnic Univers...
1. Laughter yoga is acceptable to children with ASD and their parents.
2. Laughter yoga is feasible for anxiety and depression reduction in children with ASD and parenting stress reduction in their parents.
3. Participants in the experimental group will have significantly more reduction in depression, anxiety and parental stress than those in the wait-list-control group. conditions: Autism Spectrum Disorder conditions: Parenting Stress conditions: Depression conditions: Anxiety studyType: INTERVENTIONAL phases: NA allocat...
<|newrecord|> nctId: NCT06326242 id: IEO 1648 briefTitle: What Unmet Need for the Patients?A Focus on the Social Determinants of Health in Phase 1 Clinical Trials overallStatus: RECRUITING date: 2023-03-27 date: 2024-12-31 date: 2024-12-31 date: 2024-03-22 date: 2024-03-22 name: European Institute of Oncology class: OT...
<|newrecord|> nctId: NCT06326229 id: CEIm 3096 briefTitle: Clinical Validation of Musculoskeletal ICF Core Set in Primary Care Physiotherapy overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2025-01-31 date: 2025-09-26 date: 2024-03-22 date: 2024-04-05 name: University of Valladolid class: OTHER name: Castilla-L...
The main question it aims to answer is:
- Are the ICF entities included in the ICF Core Set under evaluation useful from a clinical point of view?
Participants will evaluate the relevance of each ICF entity included in the ICF core set according to their musculoskeletal condition. conditions: Musculoskeletal Diseases studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 385 type: ESTIMATED name: ICF entities assessment measur...
<|newrecord|> nctId: NCT06326216 id: 19-011292 id: NCI-2023-05221 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: 19-011292 type: OTHER domain: Mayo Clinic Institutional Review Board briefTitle: Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatm...
<|newrecord|> nctId: NCT06326203 id: UPECLIN-MB-8 briefTitle: Cell Therapy for Lower Limb Ulcers in Patients With Critical Limb Ischemia overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2027-07-01 date: 2027-12-31 date: 2024-03-22 date: 2024-04-10 name: UPECLIN HC FM Botucatu Unesp class: OTHER name: Conselho N...
<|newrecord|> nctId: NCT06326190 id: EORTC-2334-BTG briefTitle: 177Lu-DOTATATE for Recurrent Meningioma acronym: LUMEN-1 overallStatus: NOT_YET_RECRUITING date: 2024-11-06 date: 2027-04-14 date: 2028-12-22 date: 2024-03-22 date: 2024-03-22 name: European Organisation for Research and Treatment of Cancer - EORTC class: ...
The rationale for the LUMEN-1 trial is based on the following: (a) high somatostatin receptor (SSTR) expression in meningiomas, (b) wide-spread availability of clinically established SSTR-PET imaging, (c) proven efficacy of SSTR-targeting radioligand therapy using \[177Lu\]Lu-DOTATATE in another tumor type (neuroendocr...
<|newrecord|> nctId: NCT06326177 id: Yeditepe U - Poyraz Tuncer briefTitle: Investigating Association Between Spine, Scapular, Shoulder and Core in Swimmers overallStatus: ENROLLING_BY_INVITATION date: 2024-06-15 date: 2024-07-01 date: 2024-09-01 date: 2024-03-22 date: 2024-03-27 name: Yeditepe University class: OTHER ...
<|newrecord|> nctId: NCT06326164 id: sample briefTitle: Effect of Kinesio-taping of Lower Limbs overallStatus: RECRUITING date: 2024-02-15 date: 2024-06-15 date: 2024-07-18 date: 2024-03-22 date: 2024-03-22 name: Kafrelsheikh University class: OTHER briefSummary: The goal of this clinical trail is to test if kinesio-ta...
<|newrecord|> nctId: NCT06326151 id: UMAPS-UDATO briefTitle: Interdisciplinary Psychoeducational Intervention Programme for Caregivers of Dependent Older Adults overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2025-09-01 date: 2025-12-31 date: 2024-03-22 date: 2024-03-22 name: University of Salamanca class: OTH...
Methods: A parallel, randomized, controlled clinical trial with two arms will be conducted at the Occupational Therapy Teaching and Care Unit (UDATO) and the Municipal Psychosocial Support Unit for the Elderly (UMAPS), both of which belong to the University of Salamanca and are in agreement with the City Council of Sal...
Discussion: The objective of this study is to enhance conventional clinical practice for family caregivers of dependent older adults. This will be achieved through an interdisciplinary psychoeducational intervention that aims to reduce overload and depressive symptomatology, increase social support, improve health and ...
Participants will also be blinded and will not know which group they have been allocated to and therefore which intervention they will receive. In order to minimise any contamination between groups, the assessment process will be carried out by external research staff who will perform the measurements and who have been...
<|newrecord|> nctId: NCT06326138 id: 22121 briefTitle: Pharmacokinetics and Pharmacodynamics of Edoxaban Before and After Bariatric Surgery acronym: EXPOSE overallStatus: WITHDRAWN date: 2024-03-11 date: 2024-03-11 date: 2024-03-11 date: 2024-03-22 date: 2024-03-22 name: Institut universitaire de cardiologie et de pneu...
Participants in Group 1, edoxaban pharmacokinetic and pharmacodynamics will be evaluated before and 48 ± 5 hours after bariatric surgery (sleeve gastrectomy and Roux-en-Y gastric bypass). Participants in Group 2, edoxaban pharmacokinetic and pharmacodynamics will be evaluated only once, at 12 ± 3 months following their...
All participants will be received single oral doses of 60 mg edoxaban at each pharmacokinetic and pharmacodynamics evaluation. conditions: Bariatric Surgery Candidate studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Group 1: 12 patients waitin...
Group 2: 12 patients 12 months after Roux-en-Y gastric bypass surgery. primaryPurpose: OTHER masking: NONE count: 0 type: ACTUAL name: Edoxaban Pharmacokinetics and Pharmacodynamics measure: Pharmacokinetics edoxaban parameter measure: Pharmacokinetics edoxaban parameter measure: Pharmacokinetics edoxaban parameter mea...
<|newrecord|> nctId: NCT06326125 id: SherzadSH briefTitle: Pharmacology and Non-pharmacology Approaches in Reducing Children's Pain and Fear During Painful Procedures overallStatus: ENROLLING_BY_INVITATION date: 2023-12-15 date: 2024-04-10 date: 2024-04-10 date: 2024-03-22 date: 2024-03-28 name: Uppsala University clas...
<|newrecord|> nctId: NCT06326112 id: 4588 briefTitle: Role of Active Deresuscitation After Resuscitation: acronym: RADAR-Canada overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-03-31 date: 2025-06-30 date: 2024-03-22 date: 2024-03-22 name: Unity Health Toronto class: OTHER name: Canadian Institutes of Heal...
<|newrecord|> nctId: NCT06326099 id: R34AA030655 type: NIH link: https://reporter.nih.gov/quickSearch/R34AA030655 briefTitle: Brief Binge Eating and Drinking Online Intervention overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-04-30 date: 2026-04-30 date: 2024-03-22 date: 2024-03-22 name: University of Sou...
<|newrecord|> nctId: NCT06326086 id: REC.65-080-7-1 briefTitle: Differences in Rate of Decline in CT-defined Skeletal Muscle Mass and Physical Performance in Patients With Advanced Non-small Cell Lung Cancer Receiving Chemotherapy and Targeted Therapy/Immunotherapy, Before and After Treatment. overallStatus: RECRUITING...
<|newrecord|> nctId: NCT06326073 id: OMUKAEK2019/324 briefTitle: Interaction Between Smoking, GCF Periostin, IL17A, IL17E and Non-surgical Periodontal Therapy overallStatus: COMPLETED date: 2019-07-01 date: 2021-02-01 date: 2021-07-01 date: 2024-03-22 date: 2024-03-22 name: Ondokuz Mayıs University class: OTHER briefSu...
<|newrecord|> nctId: NCT06326060 id: NN9541-5015 id: U1111-1291-9210 type: OTHER domain: World Health Organization (WHO) id: jRCT2051230198 type: REGISTRY domain: JRCT briefTitle: A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Help People With Excess Body Weight Lose Weight overallStatu...
<|newrecord|> nctId: NCT06326047 id: NN9541-4945 id: U1111-1291-9196 type: OTHER domain: World Health Organization (WHO) id: jRCT2031230704 type: REGISTRY domain: JRCT briefTitle: A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 Diabetes overallStat...
<|newrecord|> nctId: NCT06326034 id: AAA234 briefTitle: Impact of Dapagliflozin as Add-on Therapy on Glycemic Status and Quality of Life in Type 2 Diabetic Patients overallStatus: COMPLETED date: 2022-05-01 date: 2023-01-01 date: 2023-01-01 date: 2024-03-22 date: 2024-03-22 name: Mohammed Mahmood Mohammed class: OTHER ...
It has been certained by ADA, beside the glucose lowering effect the add-on antidibetic medication should have an impact on weight management to achieve and maintain the optimum glycemic and weight control which are the goals in people without established cardiorenal risks (Vijan et al., 2014((Inzucchi et al., 2012). A...
<|newrecord|> nctId: NCT06326021 id: BJGBYY-IIT-LCYJ-2024-004 briefTitle: Optimised CD33 (FL-33) CAR T Therapy for Refractory/Relapsed Acute Myeloid Leukaemia overallStatus: RECRUITING date: 2024-04-11 date: 2026-06-15 date: 2026-12-30 date: 2024-03-22 date: 2024-04-16 name: Beijing GoBroad Hospital class: OTHER briefS...
<|newrecord|> nctId: NCT06326008 id: BJGBYY-IIT-LCYJ-2023-002 briefTitle: Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2026-03-15 date:...
<|newrecord|> nctId: NCT06325995 id: Changhai HHHospital briefTitle: Hypofractionated Post-prostatectomy Radiotherapy (HYPORT)for Localized Prostate Cancer overallStatus: RECRUITING date: 2023-10-01 date: 2025-10-01 date: 2030-10-01 date: 2024-03-22 date: 2024-03-22 name: Changhai Hospital class: OTHER briefSummary: Th...
Accumulating evidence has proven the safety and feasibility of HYPORT for localized prostate cancer.But for localized prostate cancer,the optimal dose per fraction of HYPORT is still on its way.
It is not yet known whether giving HYPORT(57.5-65 Gy in 23-26 daily fractions of 2.5 Gy ) with or COPORT may work better in treating patients with prostate cancer. conditions: Localized Prostate Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT mask...
<|newrecord|> nctId: NCT06325982 id: BYFFL-01 briefTitle: Clinical Observation of Drug Retention Enema in Preventing Acute Radiation-induced Rectal Injury overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-12-31 date: 2024-03-22 date: 2024-03-22 name: Fujian Cancer Hospital class: OTHER_GOV ...
<|newrecord|> nctId: NCT06325969 id: PCOS Immune briefTitle: PCOS Patients Immune Status Evaluation overallStatus: RECRUITING date: 2024-03-16 date: 2025-12-01 date: 2026-03-08 date: 2024-03-22 date: 2024-03-22 name: Shanghai 10th People's Hospital class: OTHER briefSummary: In this study, the investigators will includ...
<|newrecord|> nctId: NCT06325956 id: Immune status and metformin briefTitle: PCOS Immune Function Predicts Metformin Efficacy overallStatus: RECRUITING date: 2024-03-16 date: 2025-12-01 date: 2026-07-01 date: 2024-03-22 date: 2024-03-22 name: Shanghai 10th People's Hospital class: OTHER briefSummary: In this study, the...
<|newrecord|> nctId: NCT06325943 id: CIDPRIT briefTitle: Rituximab in Chronic Inflammatory Demyelinating Polyradiculoneuropathy acronym: CIDPRIT overallStatus: COMPLETED date: 2019-04-01 date: 2023-05-30 date: 2023-11-30 date: 2024-03-22 date: 2024-03-26 name: Istituto Clinico Humanitas class: OTHER name: Ospedale Mond...
Exploratory objectives are the correlation between response to rituximab therapy and the clinical form of CIDP and the presence of antibody reactivity against node of Ranvier antigens. Intervention will be Rituximab or placebo, 1 g by intravenous infusion on day 1 and 15 after randomization and concomitant treatment fo...
<|newrecord|> nctId: NCT06325930 id: RIV-HU6-105 briefTitle: A Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-HU6 overallStatus: RECRUITING date: 2024-03-26 date: 2024-05-22 date: 2024-05-22 date: 2024-03-22 date: 2024-04-17 name: Rivus Pharmaceuticals, Inc. class: INDUSTRY briefSummary: This i...
<|newrecord|> nctId: NCT06325917 id: 101271-5 briefTitle: Effect of Diabetes Self-management Education and Support on Glycemic Control Among Patients With Type 2 Diabetic acronym: DSMES overallStatus: ACTIVE_NOT_RECRUITING date: 2022-11-01 date: 2024-07-01 date: 2024-07-30 date: 2024-03-22 date: 2024-03-22 name: Univer...
purpose: the purpose of this study is to examine the effect of self-management education with ongoing support using social media (WhatsApp) on glycemic control among patients with uncontrolled diabetes.
Method: 140 patients with diabetes type 2 attending outpatients' diabetes clinic setting in Aqaba will participate in a two-arm randomized controlled trial study. Self-management education will be applied for all participants, ongoing support using social media (what's app) will be applied to the intervention group, an...
<|newrecord|> nctId: NCT06325904 id: 9138930 briefTitle: Uniportal VATS Versus Chest Tube for Early Empyema overallStatus: COMPLETED date: 2021-03-01 date: 2023-06-01 date: 2023-12-01 date: 2024-03-22 date: 2024-03-25 name: Minia University class: OTHER briefSummary: This randomized controlled study compared uniportal ...
<|newrecord|> nctId: NCT06325891 id: RP025 briefTitle: Microbiota in Gastric Cancer by Gastric Mucosal Brushing overallStatus: RECRUITING date: 2024-02-01 date: 2025-03-31 date: 2025-05-31 date: 2024-03-22 date: 2024-03-22 name: King Chulalongkorn Memorial Hospital class: OTHER briefSummary: Many studies have shown a s...
<|newrecord|> nctId: NCT06325878 id: NEU2-OSS-2022-001 briefTitle: Genetic Architecture of Chronic Inflammatory Demyelinating Polyradiculoneuropathy acronym: GEARCIDP overallStatus: RECRUITING date: 2022-11-15 date: 2025-12-31 date: 2025-12-31 date: 2024-03-22 date: 2024-03-26 name: Istituto Clinico Humanitas class: OT...
<|newrecord|> nctId: NCT06325865 id: 23C305 briefTitle: Perception of Unpleasant Sensations During Study Procedures in ALS Patients acronym: PESALS overallStatus: RECRUITING date: 2023-04-19 date: 2024-11 date: 2024-12 date: 2024-03-22 date: 2024-03-22 name: Istituto Auxologico Italiano class: OTHER briefSummary: Diagn...
Aim of this study is to investigate the unpleasant sensations perceived by ALS patients during procedures in clinical trials. Analysing what type of pain/discomfort frightens patients during diagnostic and/or therapeutic procedures, including the different methods of administration of the study drug. Provide data to im...
This is a descriptive phenomenological study and data will be analyzed according to Sundler's method. Based on the experience of the researchers and the recommendations proposed by Sandelowski, a total of 20 interviews are estimated in order to reach the theoretical saturation per category of reference. Data collection...
<|newrecord|> nctId: NCT06325852 id: 22-5772 briefTitle: Directional Bilateral Thalamic Patterned Stimulation (Chronos) overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2027-01-01 date: 2024-03-22 date: 2024-03-25 name: Alfonso Fasano class: OTHER name: Boston Scientific Corporation briefSummar...
Study Design: This study comprises two distinct phases. Phase 1 is a cross-sectional investigation designed to identify the optimal algorithm for patterned stimulation in the VIM region . Phase 2 is a prospective clinical trial focusing on the assessment of safety and efficacy of bilateral VIM-DBS in patients with esse...
Objectives: The primary objective in Phase 2 is to evaluate the safety and effectiveness of bilateral VIM-DBS in individuals with essential tremor. In Phase 1, the investigators seek to explore the impact of the Chronos programming software on tremor patients who have experienced early or late loss of benefits. conditi...
<|newrecord|> nctId: NCT06325839 id: GRU-SBF-ES-01 briefTitle: Effects of HypnoBirthing Training and Oxytocin Massage in Primiparous Pregnants overallStatus: COMPLETED date: 2023-04-01 date: 2023-09-10 date: 2023-09-10 date: 2024-03-22 date: 2024-03-22 name: Giresun University class: OTHER briefSummary: This study was ...
<|newrecord|> nctId: NCT06325826 id: GES briefTitle: The Study of the Validation of General Evaluation Score (GES) in the Prediction of Hepatocellular Carcinoma Risk Among Patients With Advanced Fibrosis and Cirrhosis Who Achieved Sustained Virological Response for Hepatitis C Virus After Direct Acting Antiviral Drugs ...
<|newrecord|> nctId: NCT06325813 id: CIN001 - ADHD PreSMART briefTitle: ADHD PreSMA Response Inhibition Therapy overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-06-30 date: 2026-12-31 date: 2024-03-22 date: 2024-03-22 name: Children's Hospital Medical Center, Cincinnati class: OTHER briefSummary: ADHD chil...
<|newrecord|> nctId: NCT06325800 id: 2021401/2023007 id: Grant type: OTHER_GRANT domain: Juan Rodés Grant (JR23/00018) briefTitle: Glycoxidation, Arterial Biomechanics, and Target Organ Damage acronym: GlycOxiTod overallStatus: RECRUITING date: 2024-01-01 date: 2024-12-31 date: 2029-12-31 date: 2024-03-22 date: 2024-04...
<|newrecord|> nctId: NCT06325787 id: S2021-211-02 briefTitle: Image-guided Thermal Ablation vs. Lobectomy for Solitary Papillary Thyroid Microcarcinoma overallStatus: COMPLETED date: 2013-05-01 date: 2017-01-31 date: 2024-01-31 date: 2024-03-22 date: 2024-03-25 name: Chinese PLA General Hospital class: OTHER briefSumma...
<|newrecord|> nctId: NCT06325774 id: Changhai HHospital briefTitle: Radical Hypofractionated Radiotherapy for Localized Prostate Cancer overallStatus: RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2031-04-01 date: 2024-03-22 date: 2024-03-22 name: Changhai Hospital class: OTHER briefSummary: The aim of this trial ...
Hypofractionated radiotherapy delivers higher doses of radiotherapy in a shorter time period, may enabling the killing of more tumor cells with fewer side effects.
Accumulating evidence has proven the safety and feasibility of hypofractionated radiotherapy for localized prostate cancer.But for localized prostate cancer,the optimal dose per fraction of hypofractionated radiotherapy is still on its way. conditions: Localized Prostate Cancer studyType: INTERVENTIONAL phases: NA allo...
<|newrecord|> nctId: NCT06325761 id: SY-5007-I-02 briefTitle: A Study to Evaluate the Food Effects on Pharmacokinetics of SY-5007 Tablets in Healthy Subjects overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-05-01 date: 2024-05-01 date: 2024-03-22 date: 2024-03-22 name: Shouyao Holdings (Beijing) Co. LTD cl...
<|newrecord|> nctId: NCT06325748 id: SENTI-202-101 briefTitle: SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-09 date: 2040-08 date: 2024-03-22 date: 2024-03-22 name: Senti Biosciences cl...
<|newrecord|> nctId: NCT06325735 id: 98 briefTitle: Combined Systemic Inflammatory Indices and Birth Weight overallStatus: COMPLETED date: 2019-12-01 date: 2021-02-01 date: 2024-04-01 date: 2024-03-22 date: 2024-04-18 name: University of Campania "Luigi Vanvitelli" class: OTHER briefSummary: The study aimed to explore ...
<|newrecord|> nctId: NCT06325722 id: 10001680 id: 001680-DK briefTitle: Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-07-31 date: 2026-07-31 date: 2024-03-22 date: 2024-04-26 name: National Institute of Diabetes and Digestive and Kidney...
In a previous study, participants were lived at the NIH and randomly received either a low-fat or a low-carbohydrate diet for 2 weeks and then switched to the other diet for 2 more weeks. Participants who received the low-carbohydrate diet first lost more body fat at the end of the study than those who received the low...
Objective:
To test the effects of diet order in people receiving either a low-fat or low-carbohydrate diet first for 4 weeks and then immediately switched to the other diet for another 4 weeks.
Eligibility:
Adults aged 19 to 50 years with a body mass index of 25 or more.
Design:
Participants will complete the study at their homes, but there will be 3 required visits to the NIH. Participants will drink a special type of water 2 weeks before the baseline NIH visit and collect urine samples at home to measure how many calories they burn. Before the diets begin, participants will visit the NIH for...
Participants will be asked to eat a specific diet for 4 weeks followed by a different diet for 4 weeks. All meals will be delivered to the participants homes. They will eat only the foods delivered.
Participants will weigh themselves daily. They will wear a monitor to track their physical activity and a sensor to measure their glucose levels. They will prick their finger each morning to test a drop of blood for ketones. Participants will meet virtually as a group with the study team weekly. Participants will have ...
<|newrecord|> nctId: NCT06325709 id: 10001580 id: 001580-I briefTitle: Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease overallStatus: ENROLLING_BY_INVITATION date: 2024-04-17 date: 2032-12-31 date: 2032-12-31 date: 2024-03-22 date: 2024-04-26 name: Na...
Chronic granulomatous disease (CGD) is a rare immune disorder caused by a mutation in the CYBB gene. People with CGD have white blood cells that do not work properly. This places them at risk of developing infections that may be life-threatening. Stem cell transplant can cure CGD but transplanting stem cells donated by...
Objective:
To learn if base-edited stem cells will improve white blood cells' ability to fight against infections in people with CGD.
Eligibility:
Males aged 18 years and older with X-linked CGD.
Design:
This is a non-randomized study. Participants with the specific mutation under study will be screened during the initial phase.