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<|newrecord|> nctId: NCT06342687 id: JagiellonianU 1 briefTitle: Compliance With ERAS and Five Year Survival After Colorectal Cancer Treatment overallStatus: COMPLETED date: 2018-01-01 date: 2022-12-31 date: 2023-12-31 date: 2024-04-02 date: 2024-04-02 name: Jagiellonian University class: OTHER briefSummary: The Enhanc... |
<|newrecord|> nctId: NCT06342674 id: Nejla CANBULAT ŞAHİNER briefTitle: Effect of Breast Milk Circadian Properties on Infant's Growth Parameters and Absorption of Nutrients acronym: The overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-04-01 date: 2025-07-31 date: 2024-04-02 date: 2024-04-02 name: Sakarya U... |
no effect on the infant's growth parameters and nutrient absorption levels by the infant. |
Hypothesis 1 (H1): Feeding preterm newborns with breast milk according to the circadian rhythm has an effect on the weight of the infants. |
Hypothesis 2 (H2): Feeding preterm newborns with breast milk according to the circadian rhythm has an effect on the height of the infants. |
Hypothesis 3 (H3): Feeding preterm newborns with breast milk according to the circadian rhythm has an effect on the head circumference of the infants. |
Hypothesis 4 (H4): Feeding preterm newborns with breast milk according to the circadian rhythm has an effect on the absorption levels of vitamins and trace elements measured in the infants' breast milk. conditions: Breast Feeding conditions: Breast Milk Collection studyType: INTERVENTIONAL phases: NA allocation: RANDOM... |
<|newrecord|> nctId: NCT06342661 id: 2022IIT205 briefTitle: Study On the Expression Level and Clinical Significance of VISTA in Patients With Vascular Cognitive Impairment overallStatus: RECRUITING date: 2023-03-01 date: 2028-11 date: 2028-11 date: 2024-04-02 date: 2024-04-02 name: First Affiliated Hospital of Harbin M... |
<|newrecord|> nctId: NCT06342648 id: Cutaneous water in renal colic briefTitle: Intracutaneous Sterile Water and Diclofenac Sodium Injections in Renal Colic overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-10-30 date: 2024-12-30 date: 2024-04-02 date: 2024-04-02 name: Suez Canal University class: OTHER bri... |
<|newrecord|> nctId: NCT06342635 id: HYD/DENMARK-001/2023 briefTitle: Hydra Single-centre Experience - Copenhagen, Denmark overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-09-30 date: 2026-10-31 date: 2024-04-02 date: 2024-04-02 name: Sahajanand Medical Technologies Limited class: INDUSTRY name: Qmed Consu... |
<|newrecord|> nctId: NCT06342622 id: Weiguo Dong briefTitle: Young-onset Colorectal Cancer Screening Based on Artificial Intelligence overallStatus: COMPLETED date: 2023-12-01 date: 2024-01-10 date: 2024-01-25 date: 2024-04-02 date: 2024-04-02 name: Renmin Hospital of Wuhan University class: OTHER briefSummary: In this... |
<|newrecord|> nctId: NCT06342609 id: 32857-01-EKSTROM briefTitle: Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease acronym: EKSTROM overallStatus: ACTIVE_NOT_RECRUITING date: 2023-03-15 date: 2024-09-07 date: 2024-09-07 date: 2024-04-02 date: 2024-04-... |
<|newrecord|> nctId: NCT06342596 id: 18597 id: J2O-MC-EKBD type: OTHER domain: Eli Lilly and Company briefTitle: A Study of Carbon-14-Labelled [14C] LY3473329 in Healthy Male Participants overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-05 date: 2024-04 date: 2024-04 date: 2024-04-02 date: 2024-04-19 name: Eli Lilly ... |
<|newrecord|> nctId: NCT06342583 id: CNR-IRIB-PRO-2024-004 briefTitle: Advanced Social Relations Training overallStatus: RECRUITING date: 2024-03-01 date: 2025-03-17 date: 2026-02-10 date: 2024-04-02 date: 2024-04-02 name: Istituto per la Ricerca e l'Innovazione Biomedica class: OTHER name: Messina, Italy briefSummary:... |
The last part, which includes sessions from the twelfth to the twenty-third, will be dedicated to the correct and conscious use of social networks with a focus on the risks that can be encountered and the correct ways to make good use of them. conditions: Autism conditions: Autism Spectrum Disorder studyType: INTERVENT... |
<|newrecord|> nctId: NCT06342570 id: 3-2023-0462 briefTitle: Quantitative Analysis of EEG Changes in Response to Nociception overallStatus: RECRUITING date: 2024-04-18 date: 2026-12-30 date: 2026-12-30 date: 2024-04-02 date: 2024-04-17 name: Gangnam Severance Hospital class: OTHER briefSummary: This study will quantify... |
<|newrecord|> nctId: NCT06342557 id: FROM briefTitle: Transitional ePRO Diary Liver acronym: MACROLIVER overallStatus: RECRUITING date: 2024-03-28 date: 2034-02-21 date: 2034-02-21 date: 2024-04-02 date: 2024-04-16 name: FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS class: OTHER briefSummary: The study is pa... |
<|newrecord|> nctId: NCT06342544 id: AGN_2023_14 briefTitle: Immediate Corticosteroid Therapy and Rituximab to Prevent Generalization in Ocular Myasthenia: a PROBE Multicenter Open-label Randomized Controlled Trial. acronym: IMCOMG overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2028-06 date: 2029-06 date: 2024-0... |
In the initial phase of the disease, 70% of patients present with ocular onset myasthenia (OMG), i.e. weakness limited to the oculomotor muscles. Generalization to skeletal, bulbar and axial muscles occurs in 20-40% of cases, with a higher frequency in the first and second years, respectively 46% and 60% of generalizat... |
Generalization is a critical event, putting the patient at risk of admission to an intensive care unit and necessitating the use of long-term immunosuppressants. |
There is currently no validated strategy for preventing generalization. On the one hand, a preventive role for corticosteroid therapy in ocular-onset myasthenia has been observed in some studies, but not confirmed by others. These contradictory results may be explained by the bias of retrospective observational studies... |
On the other hand, recent data on the use of low-dose Rituximab in the early phase of the disease shows greater efficacy than later use, enabling prolonged remission of the disease with a very good tolerability profile. |
We propose to compare in a randomized controlled trial the usual practice with a proactive strategy with a standardized corticosteroid regimen immediate at diagnosis. |
Patients with ocular myasthenia are usually treated symptomatically with acetylcholinesterase inhibitors. The introduction of corticosteroids is delayed and limited to patients with persistent disabling diplopia or ptosis with occlusion. When corticosteroids are tapered off, ocular symptoms may recur. This level of cor... |
The aim of this study is to evaluate the efficacy of a standardized proactive prevention strategy on the generalization of ocular onset myasthenias during the first 2 years. It will combine immediate treatment with corticosteroids at the time of diagnosis, with the addition of rituximab in the event of recurrence of oc... |
<|newrecord|> nctId: NCT06342531 id: 210324 briefTitle: More Effective Violence Risk Management - eDASA+APP FI acronym: eDASA+APP FI overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-12 date: 2026-12 date: 2024-04-02 date: 2024-04-02 name: University of Turku class: OTHER name: Helsinki University Central Hosp... |
<|newrecord|> nctId: NCT06342518 id: MU ESWT briefTitle: ESWT in Lateral Epicondylitis: Clinical,Ultrasonographic Evaluation overallStatus: COMPLETED date: 2020-12-01 date: 2021-09-01 date: 2021-12-01 date: 2024-04-02 date: 2024-04-02 name: Istanbul Medeniyet University class: OTHER briefSummary: This study aimed to ch... |
<|newrecord|> nctId: NCT06342505 id: MEC-2022-0037 briefTitle: Tacrolimus in CD3+ T Lymphocytes acronym: INTACT overallStatus: COMPLETED date: 2022-05-30 date: 2022-10-10 date: 2022-11-10 date: 2024-04-02 date: 2024-04-02 name: Erasmus Medical Center class: OTHER briefSummary: The goal of this study is to measure conce... |
(i) What is the ratio between the tacrolimus concentration within T lymphocytes and in whole blood?; (ii) What is the correlation between tacrolimus concentrations and the effects of the drug? |
Participants will: |
* Receive standard clinical care; |
* Undergo two extra venipunctures for the collection of blood. conditions: Immunosuppression studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 28 type: ACTUAL name: Venipunctures measure: The intracellular tacrolimus concentration in CD3+ T lymphocytes measure: Intracellular cytoki... |
<|newrecord|> nctId: NCT06342492 id: KCHRRF_CS Lead Failure_0025 briefTitle: Conduction System Vs Surgical Left Ventricular Epicardial Pacing For Coronary Sinus Lead Failure overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-10 date: 2024-12 date: 2024-04-02 date: 2024-04-02 name: Kansas City Heart Rhythm Resea... |
<|newrecord|> nctId: NCT06342479 id: NM: 04.20.ND:30.03.2023 briefTitle: Discharge Training for Patients With Intertrochanteric Fracture overallStatus: RECRUITING date: 2023-09-01 date: 2024-06-01 date: 2024-07-01 date: 2024-04-02 date: 2024-04-02 name: Erzurum Technical University class: OTHER briefSummary: This study... |
<|newrecord|> nctId: NCT06342466 id: 2023-358-02 briefTitle: Bortezomib, Pomalidomide, Dexamethasone For Systemic AL Amyloidosis overallStatus: RECRUITING date: 2024-04 date: 2026-12 date: 2026-12 date: 2024-04-02 date: 2024-04-02 name: Jin Lu, MD class: OTHER briefSummary: This is an open-label, multicenter, Phase 2 s... |
<|newrecord|> nctId: NCT06342453 id: STUDY00026814 id: NCI-2024-01534 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: STUDY00026814 type: OTHER domain: OHSU Knight Cancer Institute briefTitle: Examining Arts as Therapy in Children With Cancer, CREATe Trial overallStatus: NOT_YET_RECRUITING date: 2024... |
<|newrecord|> nctId: NCT06342440 id: 23228/AACRC briefTitle: Early Detection of Advanced Adenomas and Colorectal Cancer acronym: AACRC overallStatus: RECRUITING date: 2020-03-15 date: 2025-12-15 date: 2025-12-15 date: 2024-04-02 date: 2024-04-02 name: City of Hope Medical Center class: OTHER briefSummary: This study ai... |
<|newrecord|> nctId: NCT06342427 id: 23228/DESTINEX briefTitle: Stomach Cancer Exosome-based Detection acronym: DESTINEX overallStatus: RECRUITING date: 2023-03-15 date: 2025-03-15 date: 2025-03-15 date: 2024-04-02 date: 2024-04-02 name: City of Hope Medical Center class: OTHER briefSummary: Gastric cancer continues to... |
<|newrecord|> nctId: NCT06342414 id: 23228/ELUCIDATE briefTitle: An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer acronym: ELUCIDATE overallStatus: RECRUITING date: 2024-03-15 date: 2025-03-15 date: 2025-03-15 date: 2024-04-02 date: 2024-04-02 name: City of Hope Medical Center class... |
<|newrecord|> nctId: NCT06342401 id: 23228/ENCODE briefTitle: Early Onset Colorectal Cancer Detection acronym: ENCODE overallStatus: RECRUITING date: 2023-04-15 date: 2025-04-15 date: 2025-10-15 date: 2024-04-02 date: 2024-04-02 name: City of Hope Medical Center class: OTHER briefSummary: Colorectal cancer (CRC) once p... |
This study aims to detect EOCRC with a non-invasive test, using a blood-based molecular assay based on microRNA (ribonucleic acid) conditions: Colorectal Cancer conditions: Colorectal Neoplasms conditions: Colorectal Adenocarcinoma conditions: Colorectal Cancer Stage I conditions: Colorectal Cancer Stage IV conditions:... |
<|newrecord|> nctId: NCT06342388 id: 2024-0427 id: A538500 type: OTHER domain: UW- Madison id: Protocol Version 3/20/2024 type: OTHER domain: UW- Madison id: SMPH/POP HEALTH SCI/POP HLTH type: OTHER domain: UW- Madison briefTitle: Enrollment Barriers, Procedural Denials, and Loss of Medicaid Coverage overallStatus: WIT... |
1. How does a live phone call from a Navigator impact Medicaid enrollment among people who lost Medicaid coverage for procedural reasons? |
2. What is the effectiveness of outreach using a live call rather than a pre-recorded call? conditions: No Medicaid Coverage studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 0 type: ACTUAL measure: Number of people who successfully renew their Medicaid coverage within 3 months ... |
<|newrecord|> nctId: NCT06342375 id: 2024-0434 id: A538500 type: OTHER domain: UW- Madison id: Protocol Version 3/20/2024 type: OTHER domain: UW- Madison id: SMPH/POP HEALTH SCI/POP HLTH type: OTHER domain: UW- Madison briefTitle: Enrollment Barriers, Procedural Denials, and Loss of Medicaid Coverage overallStatus: NOT... |
1. How does a live phone call from a Navigator impact Medicaid enrollment among people who lost Medicaid coverage for procedural reasons? |
2. What is the effectiveness of outreach using a live call rather than a pre-recorded call? conditions: No Medicaid Coverage studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 425000 type: ESTIMATED name: Outbound phone call measure: Number... |
<|newrecord|> nctId: NCT06342362 id: SICHN/IRB-001/2024 briefTitle: Magnesium Sulfate in Neonatal HIE" overallStatus: NOT_YET_RECRUITING date: 2024-04-02 date: 2024-10-02 date: 2024-12-02 date: 2024-04-02 date: 2024-04-02 name: Sindh Institute of Child Health and Neonatology class: OTHER briefSummary: The study will in... |
<|newrecord|> nctId: NCT06342349 id: SIBP-V03-I briefTitle: A Clinical Trial of Quadrivalent Influenza Virus Split Vaccine (MDCK Cells) for Individuals Aged 6 Months and Above. overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2024-12-30 date: 2024-12-30 date: 2024-04-02 date: 2024-04-02 name: Shanghai Institute... |
<|newrecord|> nctId: NCT06342336 id: HS-IT101ST01-I briefTitle: HS-IT101 Injection in the Treatment of Advanced Solid Tumors overallStatus: RECRUITING date: 2024-01-18 date: 2026-03-31 date: 2028-03-31 date: 2024-04-02 date: 2024-04-02 name: Qingdao Sino-Cell Biomedicine Co., Ltd. class: INDUSTRY name: Cancer Institute... |
<|newrecord|> nctId: NCT06342323 id: IRB00006761-M2023235 id: ONFM-SBRT type: OTHER domain: Peking university third hospital briefTitle: The Optimal Number of Fiducial Marker for Stereotactic Body Radiotherapy acronym: ONFM-SBRT overallStatus: RECRUITING date: 2023-10-08 date: 2024-10-07 date: 2025-10-07 date: 2024-04-... |
Study Design: Prospective, single-center, exploratory clinical study. |
Patient Enrollment: The study intends to enroll patients diagnosed with malignant tumors requiring fiducial marker-guided SBRT. Each tumor type (lung, liver, pancreatic, kidney/adrenal) aims to include 15 cases. |
Informed Consent: Patients are required to sign informed consent before participating in the study, indicating their understanding of the procedures, risks, and benefits involved. |
Intervention: Enrolled patients will undergo stereotactic radiotherapy for their respective malignant tumors. During this process, fiducial markers will be implanted according to the study protocol. |
Monitoring: Following implantation of fiducial markers, the study will monitor adverse events associated with the procedure. This includes any complications or side effects resulting from the marker implantation process. |
Success Rate: The study will assess the success rate of fiducial marker implantation. This likely involves evaluating the accuracy and reliability of marker placement for guiding SBRT treatment. |
SBRT Treatment Error: The study will also monitor SBRT treatment errors. This involves tracking any deviations or inaccuracies in the delivery of stereotactic radiotherapy, potentially caused by issues such as improper fiducial marker placement or technical errors in treatment administration. |
Overall, the study aims to explore the feasibility and effectiveness of using fiducial marker-guided SBRT for treating various types of malignant tumors to assess both the safety and the efficacy with a focus on patient outcomes and treatment accuracy. conditions: Lung Cancer conditions: Liver Cancer conditions: Pancre... |
<|newrecord|> nctId: NCT06342310 id: RE104-201-PPD briefTitle: RE104 Safety and Efficacy Study in Postpartum Depression overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-06 date: 2024-04-02 date: 2024-04-03 name: Reunion Neuroscience Inc class: INDUSTRY briefSummary: The purpose of this study is ... |
<|newrecord|> nctId: NCT06342297 id: OLL-1003043 briefTitle: Dermatoscopy Guided Resection for Skin Cancer overallStatus: RECRUITING date: 2024-01-14 date: 2025-12-15 date: 2026-01-14 date: 2024-04-02 date: 2024-04-02 name: Region Örebro County class: OTHER briefSummary: In this randomizid controlled trial the aim is t... |
<|newrecord|> nctId: NCT06342284 id: NYPC ERC# 2021-030 briefTitle: Patient-Generated Health Data Collection During Chemoradiotherapy for Lung Cancer acronym: PGHD overallStatus: RECRUITING date: 2024-03-22 date: 2026-03-21 date: 2031-03-21 date: 2024-04-02 date: 2024-04-02 name: The New York Proton Center class: OTHER... |
<|newrecord|> nctId: NCT06342271 id: 24-2023 briefTitle: Effects of Nordic Walking and Free Walking on Arm Swing Parameters and Gait in Parkinson's Disease overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-03-30 date: 2025-06-30 date: 2024-04-02 date: 2024-04-02 name: University of Talca class: OTHER briefS... |
Nordic walking (NW) is a form of physical exercise characterized by the use of walking poles, which could contribute positively to arm swing movement and, thus, gait. |
This clinical trial aims to compare Nordic Walking with free walking (FW) protocol training and investigate their effects on arm swing and gait parameters in people with PD. |
The study hypothesizes that NW training will reduce asymmetry and increase arm swing amplitudes during gait to a greater extent than FW. Also, improvements in arm swing could positively influence lower limb performance during regular gait, increasing gait speed, stride length, functional mobility, and quality of life. |
People with PD will complete 24 supervised NW or FW training sessions for 12 weeks. Both trainings will be identical in volume and intensity, the only difference will be the use of poles in the NW group. Blinded researchers will conduct evaluations at baseline (T0), post-intervention (T1), and in one-month follow-up (T... |
<|newrecord|> nctId: NCT06342258 id: HS-23-00611 briefTitle: COES: Curing Order Effects on Sealants acronym: COES overallStatus: RECRUITING date: 2024-02-23 date: 2026-06-30 date: 2026-06-30 date: 2024-04-02 date: 2024-04-11 name: University of Southern California class: OTHER briefSummary: Background: Sealants are a g... |
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