text stringlengths 0 197k |
|---|
<|newrecord|> nctId: NCT06343441 id: SH9H-2024-T29-2 briefTitle: Accuracy of Two Methods of Making Impressions for Complete-arch Implant Supported Fixed Prosthesis overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2024-12-31 date: 2024-12-31 date: 2024-04-02 date: 2024-04-02 name: Shanghai Ninth People's Hospita... |
<|newrecord|> nctId: NCT06343428 id: IEO 1519 briefTitle: Definition of a Multiparametric Prognostic and Predictive System of Classification of NET G3 Patients acronym: TAPIOCA overallStatus: RECRUITING date: 2021-07-19 date: 2024-07-19 date: 2026-07-19 date: 2024-04-02 date: 2024-04-02 name: European Institute of Onco... |
The new classification made it possible to separate NETs G3 from high-grade, poorly-differentiated, NENs that are called neuroendocrine carcinomas (NECs). |
However, in clinical practice, we observed that several clinical, pathological and radiological differences are arising among NET G3 patients, suggesting that a multiparametric definition of NET G3 is needed. conditions: Neuroendocrine Neoplasm studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPE... |
<|newrecord|> nctId: NCT06343415 id: H-23052844 briefTitle: Robot-assisted Training After Traumatic Brain Injury and Disorders of Consciousness overallStatus: RECRUITING date: 2024-04-16 date: 2025-04-30 date: 2025-07-31 date: 2024-04-02 date: 2024-04-17 name: Christina Kruuse class: OTHER briefSummary: The goal of thi... |
* Is the protocol feasible concerning inclusion in the study? |
* Is the protocol feasible concerning protocol completion? Participants will randomly be assigned to either five days of robot-assisted gait training (GAIT), two days of pause, then five days of robot-assisted step training (STEP) or vice versa. |
The investigators will explore and compare safety events, physiological measures and physical activity levels, behavioural measures, and functional disability outcomes. Further, the investigators report intervention and technical parameters in detail. conditions: Traumatic Brain Injury conditions: Disorders of Consciou... |
Data analyses are blinded by coding and blinding the groups (groups A and B) for the statistical analyses. After the analysis, two separate conclusions will be written before lifting the blinding and revealing the results. whoMasked: OUTCOMES_ASSESSOR count: 17 type: ESTIMATED name: GAIT-assisted training name: STEP-as... |
<|newrecord|> nctId: NCT06343402 id: TBBO8520-101 id: ONKORAS-101 type: OTHER domain: TheRas briefTitle: Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer overallStatus: RECRUITING date: 2024-04 date: 2027-08 date: 2028-02 date: 2024-04-02 date: 2024-04-22 name: TheRas, Inc class: INDUSTRY br... |
<|newrecord|> nctId: NCT06343389 id: Soh-Med-24-03-14MS briefTitle: Acute Kidney Injury in Patients With Liver Cirrhosis overallStatus: RECRUITING date: 2024-04 date: 2024-10 date: 2025-04 date: 2024-04-02 date: 2024-04-02 name: Sohag University class: OTHER briefSummary: In our locality, limited studies have discussed... |
<|newrecord|> nctId: NCT06343376 id: I-3641523 id: NCI-2024-01818 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: I-3641523 type: OTHER domain: Roswell Park Cancer Institute briefTitle: Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hem... |
<|newrecord|> nctId: NCT06343363 id: 318352 briefTitle: Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety acronym: EARLY-Edge overallStatus: RECRUITING date: 2023-05-01 date: 2025-05 date: 2025-12 date: 2024-04-02 date: 2024-04-02 name: Oxford University Hospitals N... |
Transcatheter edge-to-edge repair (TEER) procedures have increasingly been used to improve the severity of both MR and TR, offering patients symptomatic relief and reductions in heart failure hospitalisation at low procedural risk. There is considerable geographic variation in protocols to assess these patients prior t... |
This prospective, observational cohort study will examine the safety and feasibility of this practice. conditions: Mitral Regurgitation conditions: Tricuspid Regurgitation conditions: Mitral Repair conditions: Heart Failure studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type... |
<|newrecord|> nctId: NCT06343350 id: OPTDR01P briefTitle: OPTDR01 Feasibility for Automated Diabetic Retinopathy Detection overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-10-30 date: 2024-12-30 date: 2024-04-02 date: 2024-04-02 name: Optain Health class: INDUSTRY briefSummary: In the United States, only 6... |
A clear need exists for a diabetic retinopathy screening tool that can be deployed in primary care settings, addressing the shortage of specialist care and making screening more accessible to underserved populations. OPTDR01 will directly address these issues by providing accessible, high quality screening for diabetic... |
<|newrecord|> nctId: NCT06343337 id: MSKUDİSCLİNİCALTRİALS_FYİLMAZ. briefTitle: The Effects of Pregnancy on Oral Health overallStatus: COMPLETED date: 2022-05-20 date: 2023-04-01 date: 2023-04-01 date: 2024-04-02 date: 2024-04-02 name: Muğla Sıtkı Koçman University class: OTHER briefSummary: The aim of this study was t... |
The main questions it aims to answer are: |
* Does pregnancy affect caries experience and periodontal status? |
* Does pregnancy affect salivary pH and flow rate? |
* Is there a difference between pregnant and non-pregnant woman with respect to caries experience, periodontal status, salivary pH and flow rate? |
* Is there a difference among first, second and third trimester with respect to caries experience, periodontal status, salivary pH and flow rate? conditions: Pregnancy Related conditions: Dental Caries conditions: Periodontal Diseases conditions: Saliva Altered studyType: INTERVENTIONAL phases: NA allocation: NON_RANDO... |
<|newrecord|> nctId: NCT06343324 id: 2023/012 briefTitle: Effect of Web-Based Adaptation and Insomnia Severity in Individuals Using Noninvasive Ventilators at Home overallStatus: ENROLLING_BY_INVITATION date: 2024-01-01 date: 2024-02-01 date: 2024-04-01 date: 2024-04-02 date: 2024-04-03 name: KTO Karatay University cla... |
<|newrecord|> nctId: NCT06343311 id: EBUS22CD19AR100 briefTitle: T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) acronym: Starlight-1 overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2026-12-31 date: 2027-12-31 date: 2024-04-02 date: 2024-04-18 name: Estrella Biopha... |
<|newrecord|> nctId: NCT06343298 id: ES_MANP_2001 briefTitle: To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2025-07-01 date: 2025-08-01 date: 2024-04-02 date: 2024-04-10 name: E-Star BioTech, LLC class: ... |
<|newrecord|> nctId: NCT06343285 id: 20231215 briefTitle: Upper Limb Tremor Reduction in Essential Tremor Patients acronym: ULTRE overallStatus: RECRUITING date: 2024-01-01 date: 2024-05 date: 2024-06 date: 2024-04-02 date: 2024-04-03 name: Encora, Inc. class: INDUSTRY briefSummary: This study is designed to demonstrat... |
<|newrecord|> nctId: NCT06343272 id: LEGO briefTitle: Lymphocyte Enhancement in Gastroenteric Oncology overallStatus: RECRUITING date: 2022-03-22 date: 2024-12-22 date: 2025-02-28 date: 2024-04-02 date: 2024-04-03 name: Fondazione IRCCS Policlinico San Matteo di Pavia class: OTHER name: University of Pavia briefSummary... |
<|newrecord|> nctId: NCT06343259 id: 2534 briefTitle: The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-08-01 date: 2024-08-14 date: 2024-04-02 date: 2024-04-02 name: Sisli Hamidiye Etfal Training and Research Hospital class:... |
<|newrecord|> nctId: NCT06343246 id: MustafaKemalU briefTitle: Functional Inspiratory Muscle Training in Patients Diagnosed With Hypertension overallStatus: RECRUITING date: 2023-05-01 date: 2024-03-30 date: 2024-03-30 date: 2024-04-02 date: 2024-04-02 name: Mustafa Kemal University class: OTHER briefSummary: This stud... |
<|newrecord|> nctId: NCT06343233 id: FATE briefTitle: FAiling HearT in the Elderly (FATE) Study acronym: FATE overallStatus: RECRUITING date: 2019-11-19 date: 2024-12 date: 2024-12 date: 2024-04-02 date: 2024-04-02 name: IRCCS Multimedica class: OTHER briefSummary: In 2015 the Italian Ministry of Health invited the Car... |
The Study aims to examine the impact of clinical practice and therapies, analytically considering treatments and other important covariates that contribute in a complex manner to the therapeutic success of patients with heart failure. conditions: Heart Failure conditions: Frailty studyType: OBSERVATIONAL observationalM... |
<|newrecord|> nctId: NCT06343220 id: AWARE 2.0 briefTitle: Project AWARE 2.0 to Improve Awareness, Willingness and Ability for Research and Enrollment in Clinical Research overallStatus: RECRUITING date: 2024-04-10 date: 2024-09 date: 2024-09 date: 2024-04-02 date: 2024-04-29 name: Huntington Study Group class: NETWORK... |
<|newrecord|> nctId: NCT06343207 id: 249637 briefTitle: Percussive Therapy Reduced EMG Activity During Calf Raise in Limbs With and Without Chronic Ankle Instability overallStatus: COMPLETED date: 2022-11-22 date: 2023-02-02 date: 2023-02-02 date: 2024-04-02 date: 2024-04-02 name: Charles University, Czech Republic cla... |
<|newrecord|> nctId: NCT06343194 id: 6162 briefTitle: Changes in Electromyographic Activity in Aligner Treatment of Adult Patients With and Without Nocturnal Bruxism acronym: EMG_BRUX overallStatus: RECRUITING date: 2023-02-09 date: 2024-05-31 date: 2024-12-22 date: 2024-04-02 date: 2024-04-11 name: Fondazione Policlin... |
The aim of the investigators is to evaluate the effect of treatment on the masticatory muscles and the changes related to the tropism of the masseter muscles using Bruxoff ® device, before and after the beginning of the therapy. Bruxoff ® is a holter that assesses the contractions of the masseter muscles and the heart ... |
The plan is to compare treatment with clear aligners for bruxism and non-bruxism patients. |
The results will allow the investigators to evaluate the progress of clear aligner therapy in bruxism patients and compare them with those of non-bruxism patients. conditions: Sleep Bruxism conditions: Masseter Muscle Hypertrophy conditions: Grinding Teeth studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED... |
<|newrecord|> nctId: NCT06343181 id: IEO 1824 briefTitle: A Qualitative Study on Treatment Adherence in Patients With Metastatic Breast Cancer overallStatus: RECRUITING date: 2022-10-03 date: 2024-12-31 date: 2024-12-31 date: 2024-04-02 date: 2024-04-02 name: European Institute of Oncology class: OTHER briefSummary: Qu... |
Patients with metastatic breast cancer receiving or having received oral oncologic therapy, and attending the Division of Medical Senology at the European Institute of Oncology, will be included and enrolled in this research project." conditions: Metastatic Breast Cancer studyType: OBSERVATIONAL observationalModel: CAS... |
<|newrecord|> nctId: NCT06343168 id: frailty briefTitle: Prevalence of Frailty and Associated Factors in Coronary Artery Bypass Patients overallStatus: COMPLETED date: 2021-02-18 date: 2022-02-18 date: 2022-02-18 date: 2024-04-02 date: 2024-04-02 name: Uşak University class: OTHER briefSummary: This study aimed to dete... |
The main question it aims to answer are: |
What are the prevalence of and factors affecting frailty in patients with coronary artery bypass graft Type of study: descriptive cross-sectional study Participant population: coronary artery bypass grafting patients conditions: Frailty studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL... |
<|newrecord|> nctId: NCT06343155 id: E-10840098-202.3.02-235 briefTitle: Effect of Chronic Low Back Pain Treatment on Temporomandibular Disorder" overallStatus: NOT_YET_RECRUITING date: 2024-04-11 date: 2024-05-27 date: 2024-06-03 date: 2024-04-02 date: 2024-04-03 name: Medipol University class: OTHER briefSummary: Acc... |
<|newrecord|> nctId: NCT06343142 id: 42038 briefTitle: Effects of Time of Day and Nut Intake on Cognitive Performance overallStatus: RECRUITING date: 2024-04-08 date: 2025-02-28 date: 2025-06-30 date: 2024-04-02 date: 2024-04-04 name: Monash University class: OTHER briefSummary: This is a 2 x 2-factor crossover design ... |
<|newrecord|> nctId: NCT06343129 id: 3817 briefTitle: Effects of a Whole-food, Plant-based Nutrition Program on BP and Potassium in Subjects With CKD overallStatus: COMPLETED date: 2020-10-26 date: 2022-12-12 date: 2022-12-12 date: 2024-04-02 date: 2024-04-17 name: University of Rochester class: OTHER name: Rochester L... |
<|newrecord|> nctId: NCT06343116 id: BPL-Nim-CRC-3001 briefTitle: Nimotuzumab Combined With Trifluridine/Tipiracil in the Treatment of Refractory Metastatic Colorectal Cancer acronym: NOTABLE-308 overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-04 date: 2027-04 date: 2024-04-02 date: 2024-04-02 name: Biotech ... |
<|newrecord|> nctId: NCT06343103 id: IEO 1735 briefTitle: Study Evaluating Occupational Exposure to Antineoplastic Drugs acronym: BRIC overallStatus: RECRUITING date: 2022-08-02 date: 2025-12-31 date: 2025-12-31 date: 2024-04-02 date: 2024-04-02 name: European Institute of Oncology class: OTHER briefSummary: The multic... |
The control group is selected based on the characteristics of the exposed group to ensure a homogeneous sample in terms of size and characteristics. conditions: Cytotoxicity studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 500 ty... |
<|newrecord|> nctId: NCT06343090 id: BJGBYY-IIT-LCYJ-2023-003 briefTitle: Clinical Trial of CD19 and CD22 CAR Sequential Therapy Versus Single CD19 CAR Bridging to HSCT for r/r B-ALL Patients overallStatus: RECRUITING date: 2024-04-12 date: 2042-12-01 date: 2043-09-30 date: 2024-04-02 date: 2024-04-18 name: Beijing GoB... |
<|newrecord|> nctId: NCT06343077 id: STUDY-22-00106 briefTitle: Intratumoral and Systemic Hiltonol® (Poly-ICLC) in Prostate Cancer Patients on Active Surveillance overallStatus: RECRUITING date: 2024-01-16 date: 2026-12-31 date: 2026-12-31 date: 2024-04-02 date: 2024-04-02 name: Ashutosh Kumar Tewari class: OTHER name:... |
<|newrecord|> nctId: NCT06343064 id: PLB1001/PLB1004-NSCLC-Ib/II-01 briefTitle: Vebreltinib Plus PLB1004 in EGFR-mutated, Advanced NSCLC With MET Amplification or MET Overexpression Following EGFR-TKI overallStatus: RECRUITING date: 2023-06-13 date: 2024-12-31 date: 2025-06-30 date: 2024-04-02 date: 2024-04-02 name: Av... |
<|newrecord|> nctId: NCT06343051 id: STUDY-23-01681 briefTitle: USCOM in Newly Diagnosed FGR Cases acronym: USCOM FGR overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-06 date: 2026-06 date: 2024-04-02 date: 2024-04-02 name: Icahn School of Medicine at Mount Sinai class: OTHER briefSummary: The purpose of this... |
<|newrecord|> nctId: NCT06343038 id: 2023-01868; th23Nicolas briefTitle: Targeted Radionuclide Therapy in Metastatic Prostate Cancer Using a New PSMA Ligand Radiolabelled With Terbium-161 (161Tb-SibuDAB) - Dose Identification/Escalation Phase Ia/b Study acronym: PROGNOSTICS overallStatus: NOT_YET_RECRUITING date: 2024-... |
In the first part of the study researchers will compare the new treatment to the old one on prostate cancer patients using very low doses, not strong enough to treat nor to cause strong adverse reactions. Each patient will eventually receive both treatments, but one at a time. |
The aim of the second part of the study is to find the best dose of the new treatment for patients. This means finding the dose that offers the most benefits with the fewest side effects. |
The performance of different prostate cancer diagnostic methods is also in scope of the study. conditions: Castration-resistant Prostate Cancer studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: In Phase Ia: |
Radiation dosimetry driven, head-to-head in cross-over design comparison of tumour and critical organ absorbed doses after sequential non-therapeutic injections of 161Tb-SibuDAB and 177Lu-PSMA-I\&T in the same mCRPC patients undergoing standard 177Lu-PSMA-I\&T RLT. |
In Phase Ib: |
Clinical and radiation dosimetry-based dose escalation study, with a classical 3+3 design, to identify the optimal biologic dose (injected activity) of 161Tb-SibuDAB for safe and effective RLT. primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 25 type: ESTIMATED name: Injection, 161Tb-SibuDAB,1GBq... |
<|newrecord|> nctId: NCT06343025 id: Hasan Kalyoncu University briefTitle: The Effects of Tai Chi and Pilates for Individuals With Prediabetes overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-06 date: 2025-09 date: 2024-04-02 date: 2024-04-02 name: Nigde Omer Halisdemir University class: OTHER name: Hasan Kal... |
<|newrecord|> nctId: NCT06343012 id: 0305900 briefTitle: Caring Leadership Intervention Program for First-Line Nurse Managers overallStatus: COMPLETED date: 2022-07-01 date: 2022-12-31 date: 2022-12-31 date: 2024-04-02 date: 2024-04-02 name: Matrouh University class: OTHER briefSummary: Caring leadership can help first... |
<|newrecord|> nctId: NCT06342999 id: 22-012399 briefTitle: Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2035-07 date: 2035-07 date: 2024-04-02 date: 2024-04-10 name: Mauro H. Schenone class: OTHER briefSummary: The purpose of this research... |
<|newrecord|> nctId: NCT06342986 id: 2023LS185 id: P01CA111412 type: NIH link: https://reporter.nih.gov/quickSearch/P01CA111412 briefTitle: Intraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2028-06-30 date: 2029-06-30 date:... |
<|newrecord|> nctId: NCT06342973 id: 5591 briefTitle: Horizontal Ridge Augmentation With Demineralized Bone Allograft Layered With Xenograft - a Case Series overallStatus: RECRUITING date: 2024-03-27 date: 2025-05-30 date: 2025-05-30 date: 2024-04-02 date: 2024-04-02 name: Louisiana State University Health Sciences Cen... |
<|newrecord|> nctId: NCT06342960 id: KYV101-003 briefTitle: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis (KYSA-3) overallStatus: RECRUITING date: 2022-12-01 date: 2028-10 date: 2029-01 date: 2024-04-02 date: 2024-04-02 name: Kyverna Therapeutics... |
<|newrecord|> nctId: NCT06342947 id: ALG-055009-303 briefTitle: ALG-055009 in Non-cirrhotic Adults With MASH (HERALD) acronym: HERALD overallStatus: RECRUITING date: 2024-04-01 date: 2024-11-25 date: 2024-12-23 date: 2024-04-02 date: 2024-04-25 name: Aligos Therapeutics class: INDUSTRY briefSummary: This is a Phase 2a ... |
<|newrecord|> nctId: NCT06342934 id: INT157/20 briefTitle: Radiomics and Machine Learning in the Diagnosis of Ovarian Masses acronym: Multi-AROMA overallStatus: COMPLETED date: 2020-07-22 date: 2023-12-31 date: 2023-12-31 date: 2024-04-02 date: 2024-04-02 name: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano cla... |
Several ultrasound models have been developed to help gynecologists define the risk of malignancy of adnexal masses. In order to use the predictive models, the examiner had to collect certain ultrasound features of the lesion which, integrated with the patient's clinical and / or biochemical characteristics, provided a... |
Recently radiomics is emerging as an interesting tool to be applied to diagnostic imaging (computed tomography, magnetic resonance and even ultrasound). Radiomics is the evaluation of images through complex software that allows to 'read' the intrinsic characteristics of the tissue identifying aspects that are not visib... |
Radiomics applied to artificial intelligence for the creation of predictive models represents an interesting tool to overcome the limitations of previous models, at least partly dependent on the operator's experience. |
Among the serous ovarian cancer, those with BRCA gene mutation represent an interesting subgroup and are characterized by a different pathophysiological history than wild type tumors due to greater chemosensitivity and the possibility of targeted treatment with antiangiogenic drugs and PARP-inhibitors. |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.