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<|newrecord|> nctId: NCT06313476 id: SYSKY-2024-030-01 briefTitle: AMH Predicts Postchemotherapy Menopause in Premenopausal Breast Cancer Patients overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2026-04-30 date: 2026-04-30 date: 2024-03-15 date: 2024-03-15 name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen Uni... |
<|newrecord|> nctId: NCT06313463 id: SYSKY-2023-1282-02 briefTitle: Study Of Capecitabine Combined With Camrelizumab For Non-pCR TNBC With TLS After Neoadjuvant Chemoterapy overallStatus: RECRUITING date: 2024-03 date: 2031-09 date: 2035-12 date: 2024-03-15 date: 2024-03-15 name: Sun Yat-Sen Memorial Hospital of Sun Ya... |
The study anticipates a total sample size of 375 patients, who will be randomly assigned to either the experimental group or the control group. The experimental group will receive 8 cycles of adjuvant therapy of capecitabine and camrelizumab. The control group will receive 8 cycles of adjuvant therapy with capecitabine... |
<|newrecord|> nctId: NCT06313450 id: B2023-110-X02 briefTitle: De-escalated Radiotherapy for Primary Tumor After Neoadjuvant Therapy With Toripalimab Plus Chemotherapy for Nasopharyngeal Carcinoma overallStatus: RECRUITING date: 2024-03-04 date: 2026-02-01 date: 2028-02-01 date: 2024-03-15 date: 2024-03-19 name: Sun Ya... |
<|newrecord|> nctId: NCT06313437 id: 24-021 briefTitle: Revumenib in Combination With 7+3 + Midostaurin in AML overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2026-03-02 date: 2027-03-02 date: 2024-03-15 date: 2024-03-21 name: Maximilian Stahl, MD class: OTHER name: Syndax Pharmaceuticals briefSummary: This resea... |
The names of the study drugs involved in this study are: |
* Revumenib (SNDX-5613) (a type of menin inhibitor) |
* Midostaurin (a type of multi-kinase including FLT3 inhibitor) |
* Cytarabine (a type of antineoplastic agent) |
* Daunorubicin (a type of antineoplastic agent) conditions: Acute Myeloid Leukemia conditions: AML, Adult conditions: AML With Gene Mutations conditions: AML conditions: Leukemia studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE cou... |
<|newrecord|> nctId: NCT06313424 id: 9029 briefTitle: Arthroscopic Treatment of Meniscal Lesions on Healthy Meniscus in Children and Adolescents acronym: ATML overallStatus: RECRUITING date: 2023-08-29 date: 2024-04 date: 2024-04-29 date: 2024-03-15 date: 2024-03-15 name: University Hospital, Strasbourg, France class: ... |
More precisely, it is a question of determining whether arthroscopic repair of isolated meniscal lesions in children gives good results and what factors influence them, with the aim of improving the care of children suffering from meniscal lesions. |
The treatment of meniscal lesions comes down to either conservative or restorative treatment or non-conservative treatment by meniscectomy. For most authors, the treatment of meniscal lesions must remain restorative through meniscal suture, leaving no room for meniscectomy. The open approach has given way to the arthro... |
Based on this observation, the present study aims to describe the results of repairs of meniscal lesions in pediatric traumatology. conditions: Knee Injuries studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: RETROSPECTIVE count: 120 type: ESTIMATED measure: description of the results of repairs... |
<|newrecord|> nctId: NCT06313411 id: 8778 briefTitle: How do I Perform a Laparoscopic Removal of a Pelvic Retroperitoneal Schwannoma acronym: PRS overallStatus: RECRUITING date: 2022-11-23 date: 2024-04 date: 2024-04 date: 2024-03-15 date: 2024-03-15 name: University Hospital, Strasbourg, France class: OTHER briefSumma... |
Retroperitoneal schwannoma is often discovered during the exploration of unexplained lumbo-pelvic pain, or in the face of compression of nearby organs. Abdominopelvic CT and magnetic resonance imaging are essential to characterize the mass and verify its extension. The precise diagnosis is based on the pathological exa... |
Acquiring the surgical techniques and skills necessary to carry out these types of procedures is essential to providing optimal patient care. conditions: Endometriosis Pelvic studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 1 type: ESTIMATED measure: laparoscopic removal of a... |
<|newrecord|> nctId: NCT06313398 id: 10001883 id: 001883-H briefTitle: Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling overallStatus: RECRUITING date: 2024-05-01 date: 2029-05-01 date: 2029-06-15 date: 2024-03-15 date: 2024-04-26 name: National Heart, Lung, a... |
Sickle cell disease (SCD) is an inherited disorder of the blood. SCD causes red blood cells (RBCs) to die early. This can lead to a shortage of healthy cells. SCD and other blood disorders can be managed with drugs or cured with a bone marrow transplant. Researchers want to know how long RBCs survive in people with SCD... |
Objective: |
To learn how long RBCs survive in the body in people with SCD and other blood disorders compared to those whose disease was cured with a bone marrow transplant. |
Eligibility: |
People aged 18 years or older with SCD or another inherited blood disorder. People whose SCD or blood disorder was cured with a bone marrow transplant are also needed. |
Design: |
Participants will be screened. They will have a physical exam with blood and urine tests. |
Participants will have about 7 tablespoons of blood drawn. In the lab, this blood will be mixed with a vitamin called biotin. Biotin sticks to the outside of RBCs. This process is called "biotin labeling of RBCs." The next day, the participant s own biotin-labeled RBCs will be returned to their bloodstream. |
Participants will return regularly to have smaller blood samples (about 2 teaspoons) drawn. These samples will be tested to detect the percentage of cells that have biotin labels. These visits may be every 2 weeks, 4 weeks, or some other interval. Participants will continue this schedule for up to 20 weeks or until bio... |
<|newrecord|> nctId: NCT06313385 id: 22-10-1180 briefTitle: Investigating the Impact of Indocyanine Green Titration on Fluorescent Intensity in Free Flap : An Exploration of Alternative Indicators overallStatus: ACTIVE_NOT_RECRUITING date: 2023-01-01 date: 2024-03-29 date: 2024-03-29 date: 2024-03-15 date: 2024-03-15 n... |
<|newrecord|> nctId: NCT06313372 id: CA2085 briefTitle: Interpreting Respiratory Oscillometry in Adult Asthma and COPD: a Delphi Study overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-11 date: 2025-01 date: 2024-03-15 date: 2024-03-18 name: Scius Healthcare Solutions Pty Ltd class: INDUSTRY name: Chiesi Austr... |
The primary objective of the Delphi study is to aid the interpretation of respiratory oscillometry in clinical practice amongst adult patients with asthma or COPD. This will be achieved by obtaining expert consensus on: |
* Which parameters are used in clinical practice for impulse oscillometry (IOS) and for forced oscillation technique (FOT) devices. |
* What cut-offs can be used for each parameter to guide clinical practice in the management of adult patients with asthma and COPD. |
This study is based on the Delphi methodology. The Delphi study will comprise of four rounds, one brainstorming round, to formulate the consensus survey, and three rounds to attempt to obtain consensus. |
In each round a questionnaire comprising of statements and questions regarding respiratory oscillometry will be sent to participants in the Delphi study electronically using SurveyLet, an online survey platform. Participants will respond anonymously to the survey questions, indicating their level of agreement or disagr... |
Questions and statements will be repeated in subsequent rounds until the predefined level of consensus is met or the maximum number of rounds is achieved (limited to a maximum of 3 rounds). Aggregated results for each statement or question, including distribution of results and consensus status, will be provided to par... |
<|newrecord|> nctId: NCT06313359 id: FY2024-125 briefTitle: Fall Risk and Quality of Life: in Individuals With Cancer Treatment Related Peripheral Neuropathy. overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2025-03-30 date: 2025-06 date: 2024-03-15 date: 2024-03-15 name: Texas Woman's University class: OTHER b... |
<|newrecord|> nctId: NCT06313346 id: 2023.200 briefTitle: Effect of a Probiotic on Microbiota Associated With the Immune System and Inflammation. acronym: FLORABIOTIC overallStatus: RECRUITING date: 2024-01-08 date: 2024-04-30 date: 2024-06-15 date: 2024-03-15 date: 2024-03-15 name: Clinica Universidad de Navarra, Univ... |
The main questions to answer are: |
1. To study changes in the intestinal microbiota associated with immune health and inflammation related to probiotic intake. |
2. To evaluate changes in salivary cortisol after ingestion of the probiotic. |
3. To compile the number and intensity of catarrhal episodes suffered by the participants along the study. |
For this purpose, a randomized, double blind parallel study has been designed. |
Target sample size is 60 subjects. |
Participants will be allocated in two groups for 6 weeks: |
* Experimental group (n=30): daily consumption of one probiotic capsule. |
* Placebo group (n=30): daily consumption of one placebo capsule. conditions: Probiotic conditions: Microbiota studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomised, double blinded, parallel intervention primaryPurpose: PREVENTION masking: QUADR... |
<|newrecord|> nctId: NCT06313333 id: SID01 briefTitle: National Register of Moderate and Severe Adult Atopic Dermatitis acronym: ATOPYREG overallStatus: RECRUITING date: 2020-06-15 date: 2024-12-31 date: 2030-06-15 date: 2024-03-15 date: 2024-03-15 name: Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e d... |
<|newrecord|> nctId: NCT06313320 id: OAIC1344-23 briefTitle: Intraoperative Electroencephalographic Biomarkers of Postoperative Pain overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-03 date: 2026-06 date: 2024-03-15 date: 2024-03-15 name: University of Chile class: OTHER briefSummary: The goal of this study i... |
<|newrecord|> nctId: NCT06313307 id: famotidine and melasma briefTitle: The Efficacy in Treatment of Facial Melasma Combined With Thulium 1927-nm Fractional Laser and Topical H2R Antagonist overallStatus: COMPLETED date: 2023-04-01 date: 2023-11-25 date: 2023-11-25 date: 2024-03-15 date: 2024-03-15 name: Second Affilia... |
1927nm fractional laser was approved to treat melasma with no major side effects, however,hyperpigmentation and recurrence occasionally happened after laser therapy. Mast cells may paly a key role in the refractory melasma and hyperpigmentation. We hypothesized that laser treatment may stimulate the activation of pre-e... |
In the present study, the investigators speculated that H2RA can enhance the efficacy of laser treatment of melasma and block the histamine-mediated melanogenesis and dendricity to prevent postoperative hyperpigmentation. The investigators combined 1927nm fractional laser with topical famotidine for melasma as a new th... |
<|newrecord|> nctId: NCT06313294 id: 230929002 briefTitle: Postoperative Follow-up Via Text Messages Automated Versus Telephone in Patients With Continuous Regional Anesthesia acronym: txt-RA overallStatus: NOT_YET_RECRUITING date: 2024-04-04 date: 2024-09-30 date: 2024-12-31 date: 2024-03-15 date: 2024-03-29 name: Pon... |
A modern and convenient approach involves the use of immediate communication technology for follow-up after a procedure. They may contain specific questions that patients can easily answer from their mobile devices. |
Automated text messages could be associated with greater convenience and ease for patients with response rates at least like the traditional method. Phone calls, on the other hand, may be less scalable and require more human resources. |
The objective of the project is to evaluate the feasibility of monitoring through automated electronic messaging by evaluating its usability using a validated scale in Spanish. response rate on the first day and adherence rate compared to that of the traditional method. Secondarily, adherence and differences in satisfa... |
<|newrecord|> nctId: NCT06313281 id: E-18-3331 briefTitle: Effectiveness of Preoperative Antiseptic Preparation in Transnasal Skull Base Surgery overallStatus: COMPLETED date: 2019-02-01 date: 2021-09-30 date: 2021-09-30 date: 2024-03-15 date: 2024-03-20 name: King Saud University class: OTHER briefSummary: Objective: ... |
Methods: A multicenter, prospective, randomized, single-blind, three-arm trial was conducted from February 2019 to October 2021. Participants were randomized to either of three antiseptic preparation techniques: external 0.9%NaCl nasal preparation, external 0.05% chlorhexidine gluconate, or intranasal irrigation with 8... |
<|newrecord|> nctId: NCT06313268 id: LT-02-20 briefTitle: Safety of Effivia®, a Bevacizumab Biosimilar overallStatus: RECRUITING date: 2022-04-21 date: 2024-02-20 date: 2024-06-30 date: 2024-03-15 date: 2024-03-15 name: Laboratorios Liomont class: INDUSTRY name: Servicios Especializados en Ensayos Clínicos, S.C. briefS... |
<|newrecord|> nctId: NCT06313255 id: KYLL-202301-008-1 briefTitle: A Retrospective Observational Study on the Effects of Prebiotics on HBsAg Clearance overallStatus: RECRUITING date: 2023-05-09 date: 2025-12-31 date: 2025-12-31 date: 2024-03-15 date: 2024-03-15 name: Qilu Hospital of Shandong University class: OTHER br... |
Are the prebiotics have an effect in promoting HBV clearance? The participants will observe the HBV clearance rate in chronic hepatitis B patients receive prebiotics in addition to the routine antiviral therapy. |
Researchers will compare the HBV clearance rate in chronic hepatitis B patients receive prebiotics and antiviral therapy with those receiving solely antiviral therapy. conditions: Chronic Hepatitis B studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 40 type: ESTIMATED name: Pe... |
<|newrecord|> nctId: NCT06313242 id: 202403 briefTitle: Different Bowel Preparations in Magnetically Controlled Capsule Endoscopy overallStatus: RECRUITING date: 2024-03-14 date: 2025-02 date: 2025-06 date: 2024-03-15 date: 2024-03-19 name: Qilu Hospital of Shandong University class: OTHER briefSummary: The study aimed... |
<|newrecord|> nctId: NCT06313229 id: KFSIRB200-195 briefTitle: Simultaneous Implant Placement With Vertical and Horizontal Bone Augmentation overallStatus: RECRUITING date: 2024-03-13 date: 2025-03-25 date: 2025-03-31 date: 2024-03-15 date: 2024-04-16 name: Kafrelsheikh University class: OTHER briefSummary: The purpose... |
<|newrecord|> nctId: NCT06313216 id: KFSIRB200-187 briefTitle: Treatment of Peri-implant Bone Dehiscence Using Autogenous Tooth Plate overallStatus: RECRUITING date: 2024-03-15 date: 2025-03-30 date: 2025-04-15 date: 2024-03-15 date: 2024-04-09 name: Kafrelsheikh University class: OTHER briefSummary: The current trial ... |
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