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The present study included 63 patients, aged 20 to 45, with teeth that needed to be extracted. After Kafrelsheikh University research ethics committee approval, patients were randomized into 3 groups: group I patients underwent immediate implantation with Duo-Teck membrane, while group II patients underwent the same pr... |
<|newrecord|> nctId: NCT06313203 id: 'TOMCAT' SMR-4066 briefTitle: HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT) acronym: TOMCAT overallStatus: RECRUITING date: 2024-02-13 date: 2031-01 date: 2034-01 date: 2024-03-15 date: 2024-03-15 ... |
Data from the MSKCC has suggested a clinically relevant benefit from adding intrahepatic chemotherapy to systemic therapy. HAI-FUDR/DEX is not approved in Norway and can only be evaluated in a protocolized trial. Given the risk of distant disease progression with IHC, the addition of conventional systemic chemotherapy ... |
<|newrecord|> nctId: NCT06313190 id: SL-B2024-061 briefTitle: Combination of SBRT and Immunotherapy in Small Hepatocellular Carcinoma (HSBRT2402) acronym: HSBRT2402 overallStatus: NOT_YET_RECRUITING date: 2024-04-05 date: 2028-04-30 date: 2030-04-30 date: 2024-03-15 date: 2024-03-15 name: Sun Yat-sen University class: ... |
<|newrecord|> nctId: NCT06313177 id: Soh-Med-24-03-03MS briefTitle: Syndesmotic Screw in Neutral Position Versus Maximum Ankle Dorsiflexion in Ankle Fractures; Comparative Study. overallStatus: RECRUITING date: 2024-03-10 date: 2025-03-10 date: 2025-03-10 date: 2024-03-15 date: 2024-03-15 name: Sohag University class: ... |
The distal tibiofibular syndesmosis is important for stability of the ankle mortise and thus for weight transmission and walking. Syndesmotic injuries are most commonly associated with fibular fractures, but they can also occur in isolation or with damage to the lateral ankle ligament after traumatic supination. The ne... |
Most authors recommend surgical placement of a trans-fixation screw after anatomical reduction of the syndesmosis if a disruption is diagnosed to avoid complications.The main aims of treatment for dislocation of the distal tibiofibular syndesmosis are to restore the original anatomy and normal function and to recreate ... |
Some surgeons prefer Fixation of syndesmosis with screw in maximum ankle dorsiflexion and others prefer fixation in neutral position of ankle.in this study we are going to compare between these two conditions: Syndesmotic Injuries studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL p... |
<|newrecord|> nctId: NCT06313164 id: SW009 briefTitle: The Impact of Oral Glutathione on Oxidative Damage and Glycated Hemoglobin (HbA1c) Levels in Type 2 Diabetes Patients overallStatus: COMPLETED date: 2023-06-20 date: 2024-01-30 date: 2024-02-29 date: 2024-03-15 date: 2024-03-15 name: S.LAB (SOLOWAYS) class: OTHER n... |
Hypothesis: The anticipated outcome is a significant increase in GSH levels and a decrease in markers of oxidative damage among participants receiving L-glutathione compared to those in the placebo group, potentially indicating improved antioxidant defenses and some effects on glycemic regulation in T2D patients. This ... |
<|newrecord|> nctId: NCT06313151 id: Soh-Med-24-02-02MD briefTitle: The 2019 EULAR/ACR Classification Criteria as Predictor of Organ Damage in Systemic Lupus Erythematosus Patients overallStatus: RECRUITING date: 2024-03-10 date: 2026-01-15 date: 2026-03-15 date: 2024-03-15 date: 2024-03-15 name: Sohag University class... |
<|newrecord|> nctId: NCT06313138 id: NantongJS briefTitle: Effectiveness of Health Literacy Enhancement Program Among Older Persons With Physical Multimorbidity overallStatus: COMPLETED date: 2023-07-15 date: 2023-12-25 date: 2024-01-30 date: 2024-03-15 date: 2024-03-15 name: Nantong University class: OTHER name: Chian... |
Specific objectives are: |
1. To compare self-management, treatment burden, and symptom burden of older persons with physical multimorbidity between before and after receiving the individual and family health literacy enhancement program. |
2. To compare self-management, treatment burden, and symptom burden of older persons with physical multimorbidity between those receiving the individual and family health literacy enhancement program and those receiving usual care. |
Participants in the control group will receive usual care by physician and nurses during the experimental period. The usual care consists of physical examination, regular treatment protocol, patient education and telephone follow-up by community nurses. |
Participants in the interventional group will receive the program which is a group-based intervention developed by the researcher based on the Individual and Family Self-Management Theory (IFSMT) (self-management skills) and the principle of Medagogy (PITS model: Pathophysiology, Indications, Treatments, Specifies) to ... |
<|newrecord|> nctId: NCT06313125 id: E-77082166-302.08.01-796166 briefTitle: Comparison of Exercise Effects in Individuals With Flatfoot overallStatus: RECRUITING date: 2024-04-21 date: 2024-05-31 date: 2024-08-31 date: 2024-03-15 date: 2024-03-15 name: Mustafa Kemal University class: OTHER briefSummary: Flexible flatf... |
<|newrecord|> nctId: NCT06313112 id: JCDC/BHR/23/036 briefTitle: Impact of Food Insecurity on Utilization of Maternal Healthcare Services and Birth Outcomes in Slums in Pune, India overallStatus: RECRUITING date: 2023-09-25 date: 2025-02 date: 2025-02 date: 2024-03-15 date: 2024-03-15 name: Hirabai Cowasji Jehangir Med... |
The main questions it aims to answer are: |
* Is the utilization of maternal healthcare services antenatally, during delivery, and postnatally associated with household food insecurity among slum-dwelling women in Pine, India? |
* Is household food insecurity associated with birth outcomes and infant growth in these women? |
Participants will be asked: |
* For information related to socio-demographic characteristics, healthcare services utilization, food insecurity experience, dietary intake, and infant feeding indicators using a questionnaire. |
* Anthropometric measurements of the participant, her husband and her infant/s will be collected. |
* Two focused group discussions (FGDs) will also be conducted to gain insight into the perceptions of these women with respect to the utilization of maternal healthcare services. One FGD will be conducted for women who availed all the healthcare services and the other for those who did not adequately avail of the anten... |
<|newrecord|> nctId: NCT06313099 id: SakaryaAppliedSciencesUPNSC briefTitle: Parameters of the General Health Status of Prison Officers overallStatus: COMPLETED date: 2021-01-01 date: 2021-02-15 date: 2021-03-02 date: 2024-03-15 date: 2024-03-15 name: Pakize Nurgul Sen class: OTHER briefSummary: Introduction The workin... |
Method The study included a total of 141 volunteers. The musculoskeletal problems of the participants were evaluated with the Cornell Musculoskeletal Disorders Questionnaire, fatigue levels were evaluated with the Fatigue Severity Scale, depression levels were evaluated with the Beck Depression Inventory, and quality o... |
<|newrecord|> nctId: NCT06313086 id: SYSA1501-009 id: CTR20240245 type: REGISTRY domain: NMPA briefTitle: DP303c Versus Trastuzumab Emtansine in in Patients With HER2-positive Advanced Breast Cancer overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-12 date: 2028-02 date: 2024-03-15 date: 2024-03-15 name: CSPC ... |
<|newrecord|> nctId: NCT06313073 id: CHFL-BC-01 briefTitle: Neoadjuvant Radiotherapy for Breast Cancer overallStatus: RECRUITING date: 2024-04-01 date: 2026-02-15 date: 2026-02-15 date: 2024-03-15 date: 2024-03-15 name: Changhai Hospital class: OTHER briefSummary: The goal of this clinical trial is to compare the effec... |
The main questions it aims to answer are: |
* The clinical effect of neoadjuvant radiotherapy for breast cancer was determined according to the postoperative specimens. |
* Evaluate the acute and late toxicity of preoperative radiotherapy Participants will be randomly divided into two groups: the neoadjuvant radiotherapy group and the adjuvant radiotherapy group. conditions: Neoadjuvant Radiotherapy conditions: Breast Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED in... |
<|newrecord|> nctId: NCT06313060 id: 010 briefTitle: Efficacy of Carbonated Beverages in the Resolution of Alimentary Esophageal Impaction overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2025-01-01 date: 2027-01-01 date: 2024-03-15 date: 2024-03-15 name: Hospital del Río Hortega class: OTHER briefSummary: Obje... |
Methods: A clinical trial was conducted randomizing consecutive patients with a clinical diagnosis of dietary esophageal impaction to receive 200cc of carbonated drink or not at all, excluding patients with a previous diagnosis of non-esophageal stenosis that could not be overcome with a gastroscope and suspected impac... |
A telephone follow-up will be carried out after 7 days, recording possible adverse events. conditions: Esophagus Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized clinical trial primaryPurpose: TREATMENT masking: SINGLE whoMasked: I... |
<|newrecord|> nctId: NCT06313047 id: Doxorubacin in HCC briefTitle: Pharmacogenetic of Doxorubicin in HCC. overallStatus: COMPLETED date: 2021-01-01 date: 2023-12-15 date: 2023-12-30 date: 2024-03-15 date: 2024-03-28 name: Rehab Werida class: OTHER name: King Saud Bin Abdulaziz University for Health Sciences name: King... |
<|newrecord|> nctId: NCT06313034 id: GU-SBF-OPA-02 briefTitle: The Effect of Breastfeeding Training Given to Mothers With Vaginal Birth by Motivational Interview Technique overallStatus: RECRUITING date: 2023-05-01 date: 2024-03-15 date: 2024-03-15 date: 2024-03-15 date: 2024-03-15 name: Gümüşhane Universıty class: OTH... |
<|newrecord|> nctId: NCT06313021 id: 2023.12.03 briefTitle: Turkish Version of the Brief Assessment of Cognitive Impairment in Individuals With Stroke Scale overallStatus: RECRUITING date: 2024-01-15 date: 2024-04-15 date: 2024-05-15 date: 2024-03-15 date: 2024-03-15 name: Ataturk University class: OTHER briefSummary: ... |
Cognitive evaluation should include cognition, orientation, and higher cortical functions because the cognitive process is a very complex process. Assessment methods frequently used in cognitive evaluation of stroke patients; Scales and tests such as Simple Mental Test, Mini Mental State Test, Montreal Cognitive Assess... |
<|newrecord|> nctId: NCT06313008 id: EMBA-VILDA-Response trial. briefTitle: Empagliflozin Versus Vildagliptin in CAD Patients With T2DM overallStatus: RECRUITING date: 2023-08-10 date: 2024-06-01 date: 2024-06-10 date: 2024-03-15 date: 2024-04-16 name: Damanhour University class: OTHER name: Tanta University briefSumma... |
<|newrecord|> nctId: NCT06312995 id: T3DDY02 briefTitle: Investigation of a Medical Device for the Immobilisation of Radius and Ulna Fractures in Paediatric Patients acronym: T3DDY02 overallStatus: RECRUITING date: 2022-03-14 date: 2025-02-14 date: 2025-06-14 date: 2024-03-15 date: 2024-03-15 name: Meyer Children's Hos... |
The aim of the study is to evaluate the benefits in terms of comfort, safety and efficacy resulting from the use of a customised 3D-printed wrist immobilisation device in children aged between 7 and 13 with a fracture of the distal metaphysis of radius or ulna of the 'green stick' type, compared to a control group trea... |
<|newrecord|> nctId: NCT06312982 id: BFH-niCRT-04 briefTitle: A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer: From a Multicenter Phase II Cohort to a Phase III Randomized Controlled Study overallStatus: RECRUITING date: 2024-02-20 date: 2026-12 date: 2026-12 dat... |
The main questions it aims to answer are: |
To evaluate the efficacy and safety of neoadjuvant chemoradiotherapy combined with tirelizumab compared with neoadjuvant chemoradiotherapy alone for neoadjuvant therapy in patients with locally advanced rectal cancer To assess rectal or anal retention as well as quality of life. Participants will receive a long course ... |
<|newrecord|> nctId: NCT06312969 id: 2022.301 briefTitle: Technological Gaming in Cancer Survivors (WINNERS) acronym: WINNERS overallStatus: RECRUITING date: 2023-02-23 date: 2024-09 date: 2025-02 date: 2024-03-15 date: 2024-03-15 name: Antonio Pérez Martínez class: OTHER name: Hospital Ruber Internacional name: Univer... |
1. Neurocognitive deficits in cancer survivors are underestimated. They represent a very limiting long-term side effect in this group of patients. |
2. An individualized, planned and limited intervention using technological gaming can improve neurocognitive function in these pediatric patients by taking advantage of the plasticity of the central nervous system (CNS) in the pediatric age. |
3. Changes can be demonstrated not only at the cognitive level, but also at the structural and functional level using neuroimaging techniques after our intervention. |
4. In addition to the aforementioned benefits, this therapeutic tool can improve some clinical-analytical markers used in the follow-up of cancer survivors, such as immunological markers like lymphocyte populations and inflammatory cytokines. |
5. The neurocognitive effects of this therapy are not only produced at the time of the intervention, but remain until months after the intervention. |
6. The positive impact of the treatment is not only observed in the patients, but also in the psychological and emotional state of the family members. |
VARIABLES |
1. Clinically relevant improvement with moderate or large effect size in the following parameters as measured by neuropsychological tests. |
2. Statistically significant changes in neuroimaging tests. |
3. Statistically significant changes in immune and inflammatory biomarkers before and after treatment. |
STUDY DESIGN In this clinical trial, randomized versus control group, unblinded, the aim is to demonstrate the neuropsychological, structural and functional benefit of an intervention using video games in child cancer survivors. |
POPULATION OF THE STUDY The target population participating in the study will include patients of either sex aged 8-17 years who completed cancer treatment 1-5 years ago. They must have received treatment with neurotoxic potential: intrathecal/intraventricular chemotherapy, high-dose chemotherapy with crossing of the b... |
<|newrecord|> nctId: NCT06312956 id: 21C403 briefTitle: Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy acronym: MULTI-OSAS overallStatus: RECRUITING date: 2024-02-29 date: 2025-06 date: 2026-02 date: 2024-03-15 date: 2024-03-15 name: Istituto Auxol... |
Specifically, the study aims to identify pre- vs post-treatment differences in the following domains: |
* cognitive performance |
* blood expression of biomarkers related to neurodegeneration |
* psychosocial wellbeing |
Thus, patients will complete the following evaluations before (T0) and after (T1) ventilotherapy: |
* neuropsychological standard assessment |
* blood sampling |
* psychosocial self-reported questionnaires conditions: Obstructive Sleep Apnea conditions: Sleep Disorder conditions: Well-Being, Psychological conditions: Cognitive Impairment conditions: Cognitive Change conditions: Neurologic Signs studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE ... |
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