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Compared to other caregivers, APSSs may induce in patients a sense of identification which could improve the patient motivation to engage and remain in care. |
This is the main hypothesis and the main scientific objective of the PEERSIAD study, which will aim to confirm that accompanying patients with AUD using APSSs after alcohol detoxification, reduces the rate of lost-to-follow-up and improves the overall clinical outcome. conditions: Alcohol Use Disorder studyType: INTERV... |
<|newrecord|> nctId: NCT06381596 id: 2023-1715 id: A536000 type: OTHER domain: UW- Madison id: SMPH/OPHTHAL&VIS SCI/GEN type: OTHER domain: UW- Madison id: Protocol Version 3/6/2024 type: OTHER domain: UW- Madison briefTitle: Retinal Fundus Flavoprotein Fluorescence in Age Related Macular Degeneration acronym: FPF in A... |
* to evaluate patterns of increased autofluorescence FPF in the setting of geographic atrophy |
Participants will undergo FPF imaging using the OcuMet Beacon system. conditions: Geographic Atrophy conditions: Age-Related Macular Degeneration studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 40 type: ESTIMATED name: OcuMet Beacon measure:... |
<|newrecord|> nctId: NCT06381583 id: 23228/EMERALD briefTitle: A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma acronym: EMERALD overallStatus: RECRUITING date: 2023-04-15 date: 2026-06-18 date: 2026-06-18 date: 2024-04-24 date: 2024-04-25 name: City of Hope Medical Center class: OTHER br... |
<|newrecord|> nctId: NCT06381570 id: VICTORY/OZM-138 briefTitle: Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas acronym: VICTORY overallStatus: RECRUITING date: 2024-03-21 date: 2026-03-21 date: 2029-03-21 date: 2024-04-24 date: 2024-04-24 name:... |
The study will be conducted in two sequential phases: |
Phase A: A Feasibility (combination dose finding) phase, followed by Phase B: An Efficacy phase. The maximum tolerated dose (MTD)/Recommended Phase 2 Dose (RP2D) of the combination as determined in Phase A would be the dose used in Phase B. The patients on Phase A who were below the MTD/RP2D would be eligible for intra... |
<|newrecord|> nctId: NCT06381557 id: YRPG-PMS-ZYJN-RCT-2022-01 briefTitle: Cancer-related Fatigue in Patients With Breast Cancer Treatment With Zhengyuan Capsules acronym: CRF overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-03-01 date: 2027-03-01 date: 2024-04-24 date: 2024-04-24 name: Qiang Fu class: OTH... |
<|newrecord|> nctId: NCT06381544 id: fbu_nurs_elmali_002 briefTitle: The Effect of Aromatherapy Use in Nursing Skills Training overallStatus: COMPLETED date: 2024-02-12 date: 2024-02-19 date: 2024-03-06 date: 2024-04-24 date: 2024-04-24 name: Fenerbahce University class: OTHER briefSummary: Nursing education is an educ... |
Many studies have reported that students experience anxiety before their first clinical/practice experience. During skills training, it is observed that students are stressed, their hands are shaking, and they do not feel comfortable, especially before practices involving invasive interventions. This is a factor that m... |
RESEARCH HYPOTHESES: |
H0: Aromatherapy has no effect on students' anxiety and learning levels during skill training. |
H1: Aromatherapy reduces the anxiety experienced by students during skills training. |
H2: Aromatherapy has a positive effect on students' learning nursing skills. conditions: Nursing Students studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 69 type: ACTUAL name: Aromatherapy application measure: Difference between skill le... |
<|newrecord|> nctId: NCT06381531 id: 4410 briefTitle: Tracing Brain Tumors Through Deep Time acronym: TRACE overallStatus: NOT_YET_RECRUITING date: 2024-06-10 date: 2027-06-10 date: 2027-06-10 date: 2024-04-24 date: 2024-04-24 name: Tata Memorial Centre class: OTHER name: Indian Statistical Institute, Kolkata briefSumm... |
<|newrecord|> nctId: NCT06381518 id: Z2023165 briefTitle: Switching From Intravenous to Subcutaneous Infliximab in Adult Patients With Inflammatory Bowel Disease acronym: SHUFFLE overallStatus: ENROLLING_BY_INVITATION date: 2024-03-12 date: 2025-05-01 date: 2025-05-01 date: 2024-04-24 date: 2024-04-24 name: Zuyderland ... |
Methods: this is a prospective, single centre, open-label cohort study, conducted in Zuyderland Medical Centre in which 36 adult IBD patients in remission on stable IV IFX therapy are switched to SC CT-P13 of which 18 patients use an immunomodulator in addition to IFX (cohort 2). After the switch to SC CT-P13, patients... |
The study is subdivided into two phases: the IV IFX treatment phase before switching and the SC CT-P13 treatment phase after the switch. After enrolment, the subject receives a final dose of IV IFX according to their own maintenance schedule. Primary endpoints are the Area under the concentration-time curve (AUC) at st... |
<|newrecord|> nctId: NCT06381505 id: STUDY02002103 briefTitle: RetracTOR/ Retractor for Image Guided Trans-Oral Surgery overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2025-12-31 date: 2025-12-31 date: 2024-04-24 date: 2024-04-26 name: Ryan J. Halter class: OTHER name: Dartmouth College briefSummary: This stud... |
<|newrecord|> nctId: NCT06381492 id: 2024-0057 id: A536130 type: OTHER domain: UW- Madison id: SMPH/ORTHO&REHAB/PHYS THER type: OTHER domain: UW- Madison id: Protocol Version 11/20/2023 type: OTHER domain: UW- Madison briefTitle: Quantifying Patellar Tendon Microstructure Using DTI overallStatus: NOT_YET_RECRUITING dat... |
Will regions of known patellar tendon pathology present with smaller DTI scalar parameters, shorter fiber length, and lower fiber density compared to the contralateral tendon and healthy regions in the ipsilateral tendon. |
Participants will: |
* undergo MRI and ultrasound imaging |
* perform knee function test |
* complete questionnaires conditions: Patellar Tendinopathy conditions: Anterior Cruciate Ligament Reconstruction studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 40 type: ESTIMATED name: MRI name: Ultrasound (US) measure: Compare scalar parameters of known patellar tendon p... |
<|newrecord|> nctId: NCT06381479 id: B031 briefTitle: Exploring the Effects of Probiotics on Workplace Related Stress Symptoms overallStatus: RECRUITING date: 2024-04-19 date: 2024-12-31 date: 2025-03-31 date: 2024-04-24 date: 2024-04-29 name: National Taiwan Sport University class: OTHER name: Bened Biomedical Co., Lt... |
<|newrecord|> nctId: NCT06381466 id: D7250C00001 briefTitle: A Study to Investigate Safety, Tolerability, and Pharmacokinetics of Oral AZD0233 Compared With Placebo in Healthy Adult Participants. overallStatus: RECRUITING date: 2024-04-01 date: 2025-03-20 date: 2025-03-20 date: 2024-04-24 date: 2024-04-24 name: AstraZe... |
<|newrecord|> nctId: NCT06381453 id: 23-5037 briefTitle: Belimumab in Autoimmune Hepatitis acronym: BELief overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2028-04-30 date: 2029-04-30 date: 2024-04-24 date: 2024-04-24 name: University Health Network, Toronto class: OTHER name: GlaxoSmithKline briefSummary: Back... |
<|newrecord|> nctId: NCT06381440 id: PROGR-EX_MNESYS briefTitle: Traditional Versus Progressive Robot-assisted Gait Training in People With Multiple Sclerosis and Severe Gait Disability acronym: PROGR-EX overallStatus: RECRUITING date: 2023-11-15 date: 2024-11-30 date: 2024-11-30 date: 2024-04-24 date: 2024-04-24 name:... |
<|newrecord|> nctId: NCT06381427 id: 01NVF22109 briefTitle: Perioperative Interdisciplinary, Intersectoral Process Optimization in Heart Failure acronym: PeriOP-CARE HF overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2026-08-31 date: 2027-03-01 date: 2024-04-24 date: 2024-04-24 name: University of Giessen clas... |
<|newrecord|> nctId: NCT06381414 id: ChildhoodEarlyOralAging briefTitle: Childhood Early Oral Aging Syndrome: Prevalence, Etiological Factors, and Consequences on Occlusion overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-08-31 date: 2024-12-20 date: 2024-04-24 date: 2024-04-24 name: University of Nove de ... |
<|newrecord|> nctId: NCT06381401 id: MS-492-2023 briefTitle: Bupivacaine 0.125% Versus Bupivacaine 0.25% in Superficial Cervical Plexus Block on Operative Field Visibility for Adults Undergoing Tympanomastoid Surgeries overallStatus: NOT_YET_RECRUITING date: 2024-04-25 date: 2024-06-28 date: 2024-07-05 date: 2024-04-24... |
To decrease bleeding, different interventions have been proposed, including reverse Trendelenburg position, the application of topical vasoconstrictors, regional anesthesia, laryngeal mask airways, different ventilation strategies, and - most importantly - controlled systemic hypotension, with target mean arterial pres... |
The use of regional nerve blocks as an alternative to hypotensive anesthesia has gained popularity in recent years. The superficial cervical plexus block (SCPB) provides effective analgesia and reduces sympathetic activity, resulting in reduced bleeding and improved surgical conditions. The superficial cervical plexus ... |
To our knowledge, this is the first randomized controlled clinical trial investigating the effect of combined general anesthesia with SCPB using 0.125% versus 0.25% bupivacaine during tympanomastoid surgery. |
This study aims to compare the efficacy of two different concentrations of bupivacaine 0.125% \& 0.25% in Superficial Cervical Plexus Block in patients undergoing tympanomastoid surgery on operative field visualization, intraoperative hemodynamic stability, and postoperative analgesia. |
We hypothesize that bupivacaine 0.125% would be non-inferior to bupivacaine 0.25% in achieving optimal surgical field visualization, hemodynamic stability, surgeon satisfaction and postoperative analgesia. |
This prospective randomized controlled double-blinded study will be carried out on 60 patients between 21 to 70 years, with ASA I-II and undergoing tympanomastoid surgery. They were equally divided into two groups: Group A: Patients received SCPB using 0.25% bupivacaine (5ml of bupivacaine 0.5% + 5ml normal saline). Gr... |
<|newrecord|> nctId: NCT06381388 id: NL86587.041.24 briefTitle: Interaction Between the Brain Hemispheres - Key to Motor Recovery After Stroke acronym: InterAct overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2027-12-31 date: 2028-06-30 date: 2024-04-24 date: 2024-04-24 name: Jord Vink class: OTHER briefSummar... |
Objective: To determine if contralesional cTBS normalizes interhemispheric inhibition from the contralesional to ipsilesional primary motor cortex stroke patients with motor impairments. Age-matched healthy persons will serve as controls. |
Study design: A prospective, open-label within-subject intervention study |
Study population: 40 patients with first-ever ischemic stroke in one hemisphere and a unilateral paresis of the upper extremity, and 40 age-matched controls. |
Main endpoints: Primary endpoint: Interhemispheric inhibition from the contralesional to ipsilesional primary motor cortex. Secondary endpoints: contralesional intracortical inhibition; effect of contralesional TMS interference on finger tapping frequency. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocat... |
<|newrecord|> nctId: NCT06381375 id: 24-2-2024 briefTitle: Drug-drug Interactions With Anti-tuberculous Drugs overallStatus: RECRUITING date: 2024-04-30 date: 2024-12-01 date: 2025-02-15 date: 2024-04-24 date: 2024-04-24 name: Cairo University class: OTHER briefSummary: This study aims to assess the prevalence and the ... |
<|newrecord|> nctId: NCT06381362 id: IGOMIPS briefTitle: Italian Registry of Minimally Invasive Pancreatic Surgery acronym: IGOMIPS overallStatus: RECRUITING date: 2019-02-28 date: 2029-02-28 date: 2029-02-28 date: 2024-04-24 date: 2024-04-24 name: Associazione Italiana per lo Studio del Pancreas class: OTHER briefSumm... |
<|newrecord|> nctId: NCT06381349 id: GPOEM-GEMS briefTitle: Predicting Outcomes of GPOEM Using Gastric Electrical Mapping acronym: GPOEM-GEMS overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2026-06-01 date: 2024-04-24 date: 2024-04-24 name: Chris Varghese class: OTHER briefSummary: Gastric per... |
<|newrecord|> nctId: NCT06381336 id: TRAKSILVER2022 briefTitle: A Digital Home-Based Physiotherapy Program for Active Aging acronym: TRAK overallStatus: COMPLETED date: 2022-03-23 date: 2022-11-07 date: 2022-11-07 date: 2024-04-24 date: 2024-04-25 name: Trak Health Solutions S.L. class: INDUSTRY name: Basque Health Ser... |
This research will provide insight into the utility and acceptance of the digital platform as a personalised and accessible digital physiotherapy program for this population, advancing understanding in the field. |
The participants will undergo a 3-month physiotherapy program using the TRAK-SILVER platform or a paper guide based on their assigned group. Additionally, weekly uploads of health-promoting audiovisual content will enhance the intervention's holistic approach to improving older adults' well-being and functional capacit... |
<|newrecord|> nctId: NCT06381323 id: PA2024 briefTitle: The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism overallStatus: RECRUITING date: 2024-03-01 date: 2027-03-01 date: 2027-04-01 date: 2024-04-24 date: 2024-04-24 name: The Affiliated Nanjing Drum Tower Hospital of Nanjing Univ... |
<|newrecord|> nctId: NCT06381310 id: 202310077DINB briefTitle: Ultrasound-guided Cannulation of Difficult Hemodialysis Arteriovenous Access overallStatus: RECRUITING date: 2024-02-26 date: 2024-10-30 date: 2024-10-30 date: 2024-04-24 date: 2024-04-24 name: National Taiwan University Hospital class: OTHER name: National... |
Traditionally, after maturation, cannulation of new AVF/AVG was performed by trained renal nurses through physical examination, namely listening to bruits and feeling for thrills to guide needle placement, known as "blind" cannulatio. However, physical examination is not reliable for first and difficult access cannulat... |
Ultrasound (US) guided cannulation effective in identifying access location and patency. Roshan et al. reported a case study on bedside ultrasonography for AVF cannulation. The study showed decreased cannulation failure, vessel wall damage, thrombosis, and hematoma formation risks also reduced missed cannulation and in... |
Therefore, this study aims to explore the effects of ultrasound technology on arteriovenous access successful cannulation for patients with end-stage kidney disease to provide reliable research integration evidence as the basis for future clinical care. conditions: Successful Cannulation studyType: INTERVENTIONAL phase... |
<|newrecord|> nctId: NCT06381297 id: OndokusMU id: Ondokuz Mayıs University type: REGISTRY domain: Clinical research ethics committee briefTitle: Speech in Noise Discrimination Skills in Multiple Sclerosis Patients. overallStatus: COMPLETED date: 2020-10-09 date: 2023-03-23 date: 2023-04-23 date: 2024-04-24 date: 2024-... |
The main questions it aims to answer are: |
Does MS disease affect the ability to discriminate speech in noise? Does MS affect contralateral suppression results assessing medial olivocochlear function? Is there a correlation between the ability to discriminate speech in noise and contralateral suppression skills of MS patients? Data from MS patients and healthy ... |
<|newrecord|> nctId: NCT06381284 id: MG-001 briefTitle: Feasibility of Engaging and Capturing Undiagnosed Myasthenia Gravis Participants Through a Social Media Campaign Paired With a Self-moderated Assessment overallStatus: RECRUITING date: 2024-03-28 date: 2024-05-27 date: 2025-05-27 date: 2024-04-24 date: 2024-04-26 ... |
<|newrecord|> nctId: NCT06381271 id: TRUST TAVR Registry briefTitle: Transcatheter Aortic Valve Replacement for Pure Severe Aortic Valve Regurgitation overallStatus: RECRUITING date: 2018-10-30 date: 2034-10 date: 2034-10 date: 2024-04-24 date: 2024-04-24 name: Xijing Hospital class: OTHER briefSummary: The purpose of ... |
<|newrecord|> nctId: NCT06381258 id: SDF briefTitle: Fetal Cardiac Function overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-10 date: 2024-11 date: 2024-04-24 date: 2024-04-24 name: Assiut University class: OTHER briefSummary: The aim of our study is to evaluate the effect of PE and FGR on fetal cardiac funct... |
<|newrecord|> nctId: NCT06381245 id: KB/265/2023 briefTitle: First-time Ablation of Atrial Fibrillation Registry acronym: DIPE overallStatus: RECRUITING date: 2023-12-01 date: 2026-03-31 date: 2026-03-31 date: 2024-04-24 date: 2024-04-24 name: Medical University of Warsaw class: OTHER briefSummary: Atrial fibrillation ... |
The aim of this study is to investigate predictors of successful AF ablation in the following areas: (a) clinical factors, (b) electrophysiological, (c) electrocardiographic, (d) ultrasound, (e) cardiac anatomy, (f) biomarkers. conditions: Atrial Fibrillation conditions: Arrhythmia studyType: OBSERVATIONAL observationa... |
<|newrecord|> nctId: NCT06381232 id: VIOME-001 briefTitle: Collection and Analyses of Physiological, Physical, and Molecular Data From a Diverse Population overallStatus: RECRUITING date: 2018-07-23 date: 2028-07-23 date: 2028-07-23 date: 2024-04-24 date: 2024-04-24 name: Viome class: INDUSTRY briefSummary: The purpose... |
<|newrecord|> nctId: NCT06381219 id: s67001 briefTitle: Pediatric Eosinophilic Esophagitis (pedEoE): Effect of Allergen Heat Denaturation on EoE Remission: a Pilot Trial overallStatus: RECRUITING date: 2023-12-19 date: 2026-12-31 date: 2028-12-31 date: 2024-04-24 date: 2024-04-24 name: Universitaire Ziekenhuizen KU Leu... |
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