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* Is it feasible and acceptable to carry out this newly co-adapted programme with two groups of parents/carers of children with complex neurodisability under the age of 5? |
* Is it feasible to carry out an evaluation of the above programme, which could then inform a protocol for larger scale evaluation? |
The main activities for the parent/carer participants will include: |
* Attending ten "Encompass" parent/carer groups |
* Filling in questionnaires at the start and end of the groups |
* Attending an interview with the researcher to discuss their experiences |
The groups will be facilitated by a healthcare professional and a parent with lived experience. They will also be interviewed about their experiences after the groups have been completed. conditions: Complex Neurodevelopmental Disorder conditions: Cerebral Palsy studyType: INTERVENTIONAL phases: NA allocation: NA inter... |
<|newrecord|> nctId: NCT06310668 id: CBT IN substance use disorder briefTitle: Has CBT an Effect on Emotional Intelligence in Patients With Substance Use Disorder? overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-09 date: 2024-10 date: 2024-03-15 date: 2024-03-15 name: Egyptian Medical Syndicate class: OTH... |
<|newrecord|> nctId: NCT06310655 id: 202403078 briefTitle: Online Proton Adaptive Radiotherapy acronym: PARTy overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2025-05-15 date: 2025-08-31 date: 2024-03-15 date: 2024-04-11 name: Washington University School of Medicine class: OTHER briefSummary: This is a pilot s... |
Patients undergoing proton radiation therapy normally undergo extensive pre-planning for their treatment. However, accounting for uncertainties in treatment delivery remains a challenge for a variety of reasons, such as differences in patient anatomy from pre-planning to the day of treatment. Online adaptive planning i... |
<|newrecord|> nctId: NCT06310642 id: 2020-217 briefTitle: Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness acronym: PAMS overallStatus: COMPLETED date: 2021-05-20 date: 2023-03-13 date: 2023-03-13 date: 2024-03-15 date: 2024-03-15 name: CHRISTUS Health class: OTHER briefSummary: A... |
<|newrecord|> nctId: NCT06310629 id: CMUH112-REC3-163 briefTitle: Oxygenation Efficacy of "Intrinseque Health" Non-Rebreathing Mask ("IHNRM") overallStatus: RECRUITING date: 2024-02-22 date: 2025-02-21 date: 2025-05-21 date: 2024-03-15 date: 2024-03-15 name: China Medical University Hospital class: OTHER briefSummary: ... |
Numerous intubated patients emerging from the operating room require intensive critical care specialist supervision in order to transition to the regular care. This would enable higher patient turnover and more efficient utilization of hospital resources, if patient can be transited to the regular care earlier by using... |
This study is anticipated to take only around 2.5 hour per patient to complete. Patients meeting the inclusion and exclusion criteria of this study are placed on IHNRM and monitored until steady state of SpO2 of 95% or higher on 7-10 LPM has been maintained for at least 2 hours, when they can be discharged from the pos... |
The study is the parallel design study. 60 patients will be randomly selected to use the IHNRM, and 30 subjects will be placed on HFNC. Blood oxygen concentration (SpO2), respiratory rate, end tidal CO2 concentration (EtCO2), and vital sign will be recorded in the study. The endpoint of the study is to compare the effe... |
<|newrecord|> nctId: NCT06310616 id: 219888 briefTitle: A Study to Investigate the Potential Drug-Drug Interaction Between VH4524184 and Oral Contraceptive (Loestrin) in Healthy Adult Female Participants overallStatus: RECRUITING date: 2024-03-06 date: 2024-05-28 date: 2024-05-28 date: 2024-03-15 date: 2024-03-15 name:... |
<|newrecord|> nctId: NCT06310603 id: IRB-23-42 briefTitle: Determinants and Outcomes of High vs. Low Ultra-processed Feeding overallStatus: RECRUITING date: 2023-08-09 date: 2024-05-15 date: 2025-08-09 date: 2024-03-15 date: 2024-03-15 name: Oklahoma State University class: OTHER briefSummary: The goal of this clinical... |
• Does consuming a diet rich in unprocessed food improve various health outcomes? Participants will either be instructed to consume a diet rich in unprocessed food for 6 months, or consume their typical diet for 6 months. At various points in the study there will be metabolic health data collected. |
If there is a comparison group: Researchers will compare the low-processed group to the typical diet group to see if there are improvements in metabolic health. conditions: Healthy Nutrition studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: DO... |
<|newrecord|> nctId: NCT06310590 id: NRT6003-HCC-2022 id: CTR20230515 type: OTHER domain: Center for Drug Evaluation, NMPA briefTitle: Safety and Efficacy of NRT6003 in Patients With Unresectable Hepatocellular Carcinoma overallStatus: RECRUITING date: 2023-08-08 date: 2025-10-31 date: 2025-10-31 date: 2024-03-15 date:... |
<|newrecord|> nctId: NCT06310577 id: EH23-343 briefTitle: Evaluation of Leak-Free Bronchoscope Adapter to Limit Ventilated Air Volume Loss During Bronchoscopy overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-11 date: 2026-11 date: 2024-03-15 date: 2024-03-15 name: NorthShore University HealthSystem class: OTH... |
<|newrecord|> nctId: NCT06310564 id: 2023-18 briefTitle: Low and Intermediate Risk oliGometastatic coloREctal cancEr patieNts Treated With Stereotactic ABlative Radiotherapy acronym: GREENLaIT-SABR overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2031-04 date: 2031-04 date: 2024-03-15 date: 2024-03-15 name: IRCCS ... |
The reason for this research study is to evaluate whether stereotactic radiotherapy treatment (SABR), in addition to the systemic chemotherapy treatment foreseen by clinical practice for low-intermediate risk oligometastatic colorectal cancer, is able to: |
* delay possible local recurrence and/or distant polymetastatic progression |
* improve disease-free survival |
* reduce side effects in the short and long term |
thus inducing an improvement in the quality of life of patients suffering from this type of pathology. |
Therefore, as part of this randomized study, before starting first or second line systemic therapy for his tumor, the patient will be randomized to one of the following treatment arms: |
* Experimental arm: ablative stereotactic radiotherapy on all sites of oligometastatic disease (from 1 to 3 sites, performed at most within the second cycle of systemic therapy) |
* Control arm: no ablative stereotactic radiotherapy to sites of oligometastatic disease |
The procedure that is intended to be tested in the experimental arm is a stereotactic radiotherapy treatment on oligometastases (up to a maximum of 3 sites), with ablative dosage (effective biological dose \>100 Gy), performed before the start of systemic therapy of I or II line (at most within the second cycle of the ... |
It is hoped that the addition of this type of radiotherapy will increase the potential clinical benefit of the treatment in the context of colorectal cancer. conditions: Colorectal Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE coun... |
<|newrecord|> nctId: NCT06310551 id: 218804 briefTitle: First Time in Human Study of Long Acting VH4524184 Formulations overallStatus: NOT_YET_RECRUITING date: 2024-03-14 date: 2025-02-13 date: 2026-11-27 date: 2024-03-15 date: 2024-03-15 name: ViiV Healthcare class: INDUSTRY name: GlaxoSmithKline briefSummary: The pur... |
<|newrecord|> nctId: NCT06310538 id: 2024BZYLL0110 briefTitle: Clinical Study on the Treatment of Breast Hyperplasia With Kou Sha Therapy Based on Real World overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-05 date: 2024-05 date: 2024-03-15 date: 2024-03-15 name: Hongguo Rong class: OTHER briefSummary: In thi... |
<|newrecord|> nctId: NCT06310525 id: DROWN_DDF2 briefTitle: Using Machine Learning to Optimise the Danish Drowning Formula acronym: DROWN_DDF2 overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-01 date: 2024-12-31 date: 2024-12-31 date: 2024-03-15 date: 2024-03-25 name: Prehospital Center, Region Zealand class: OTHER b... |
<|newrecord|> nctId: NCT06310512 id: ANZHEN HOSPITOL-LY-04 briefTitle: Efficacy of Pharmacist Interventions Through the "Medication Therapy Management Pathway in Hypertensive Patients" acronym: PharmMTMH overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-12-31 date: 2026-06-30 date: 2024-03-15 date: 2024-03-... |
To explore the effect of pharmacists' implementation of "the medication therapy management pathway in hypertensive patients"on the patients with hypertension. |
Participants will receive structured drug treatment management at the first diagnosis. During on-site follow-up in the first, third and sixth months, as well as telephone follow-up in the second week, second and fourth months, patients will be evaluated, corresponding information will be collected and possible interven... |
Researchers will compare the non intervention group to see if patients' blood pressure will also be reduced without intervention. conditions: Hypertension conditions: Medication Therapy Management studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RES... |
<|newrecord|> nctId: NCT06310499 id: DROWN_COD briefTitle: Primary or Secondary Drowning acronym: DROWN_COD overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2025-12-31 date: 2025-12-31 date: 2024-03-15 date: 2024-03-15 name: Prehospital Center, Region Zealand class: OTHER briefSummary: According to WHO's rules,... |
Differentiating between primary and secondary drowning is difficult, as information preceding the drowning incident is rarely available. Yet, knowing the most frequent causes of secondary drowning may provide useful information to healthcare professionals working in prehospital Emergency Medical Services, as this may a... |
<|newrecord|> nctId: NCT06310486 id: DROWN_CALL briefTitle: The Emergency Call on Drowning acronym: DROWN_CALL overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-12-31 date: 2025-12-31 date: 2024-03-15 date: 2024-03-15 name: Prehospital Center, Region Zealand class: OTHER briefSummary: This study aims to 1) ... |
<|newrecord|> nctId: NCT06310473 id: NFEC-2023-582 briefTitle: Neoadjuvant Cadonilimab Plus Chemotherapy for Locally Advanced Esophagogastric Junction and Gastric Cancer Trial overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03 date: 2028-03 date: 2024-03-15 date: 2024-03-15 name: Nanfang Hospital, Southern M... |
<|newrecord|> nctId: NCT06310460 id: PCP briefTitle: Evaluation of "PreCut-Papillectomy" in Difficult Biliary Cannulation overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-31 date: 2025-02-28 date: 2024-03-15 date: 2024-03-15 name: Kliniken Ludwigsburg-Bietigheim gGmbH class: OTHER briefSummary: To evalu... |
<|newrecord|> nctId: NCT06310447 id: IstanbulBUFC2 briefTitle: Determination of Ecological Awareness and Attitudes Levels of Undergraduate Physiotherapy Students in Istanbul overallStatus: COMPLETED date: 2024-03-18 date: 2024-04-01 date: 2024-04-03 date: 2024-03-15 date: 2024-04-04 name: Istanbul Bilgi University clas... |
<|newrecord|> nctId: NCT06310434 id: PI23/00409 briefTitle: Analysis of COMPASsion and Humanisation of Adolescents Facing the End-of-life Processes. acronym: COMPAS overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2026-12 date: 2026-12 date: 2024-03-15 date: 2024-03-19 name: Instituto de Salud Carlos III class: OT... |
As the adolescents must be the protagonists of change, the study will be conducted with students enrolled in one public secondary school and in one degree in a public University, that belongs to the same "health area" in each province. The investigators also include families' and teachers' knowledge of the context beca... |
Compassion will be assessed using the Compassion for the Lives of Others Scale (COOLS), comprising 26 items. Similarly, adolescents' attitudes toward death are another important concept and will be explored through the Death Anxiety Scale (DAS), which has 15 questions. Both scales will be distributed to the adolescents... |
After the survey, a second phase will start with a Participatory Action Research (PAR) with different activities. The objective is to generate awareness of the need to improve it, allowing the participants to design the interventions, based on evidence-based proposals (cinema forum, colloquiums with testimonies of volu... |
At the end of the project, the investigators will evaluate the adolescent compassion level and create discussion groups again to understand the impact of the interventions. |
With this project, the investigators will empower new generations of people to encourage, facilitate, support, and celebrate mutual care and family and community development in end-of-life processes. The translation and implications of the results for clinical practice will contribute to reducing inequalities in health... |
<|newrecord|> nctId: NCT06310421 id: Screening_SMA briefTitle: Spinal Muscular Atrophy Neonatal Screening Program overallStatus: RECRUITING date: 2023-10-16 date: 2026-05-31 date: 2026-05-31 date: 2024-03-15 date: 2024-03-18 name: IRCCS Burlo Garofolo class: OTHER briefSummary: Spinal muscular atrophy (SMA) is a group ... |
Until a few years ago, the prognosis of type 1 SMA was poor. In the absence of therapies, the only measures were supportive (ventilation, nutrition) and the prospect, especially in the early forms, was to accompany them towards an early end of life. There are currently three treatment options available: nusinersen, ris... |
To ensure maximum benefit for affected patients, it is essential that the therapy is administered as soon as possible. Literature shows how the administration of gene therapy in pre-symptomatic subjects made it possible to achieve a better neurological outcome compared to symptomatic patients. From this perspective, th... |
<|newrecord|> nctId: NCT06310408 id: 0214022024 briefTitle: Comparison Between Nasal Mask vs Nasal Prong on Pain Response in Neonate overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2024-06-01 date: 2024-06-01 date: 2024-03-15 date: 2024-03-15 name: Indonesia University class: OTHER briefSummary: to determine t... |
1 group give nasal prong primaryPurpose: PREVENTION masking: NONE count: 44 type: ESTIMATED name: nasal mask name: nasal prong measure: pain response sex: ALL minimumAge: 26 Weeks maximumAge: 44 Weeks stdAges: CHILD hasResults: False |
<|newrecord|> nctId: NCT06310395 id: AMI_H.MAR briefTitle: Analysis of the Acute Mesenteric Ischemia in a Single Institution Over 10 Years acronym: AMI_HMAR overallStatus: NOT_YET_RECRUITING date: 2024-06-15 date: 2024-07-15 date: 2024-10-15 date: 2024-03-15 date: 2024-03-15 name: Hospital del Mar class: OTHER briefSum... |
<|newrecord|> nctId: NCT06310382 id: GH55-CRS001 briefTitle: A Phase I/II Clinical Study to Evaluate The Safety, PK, PD of GH55 in Patients With MAPK Mutant Advanced Solid Tumors overallStatus: RECRUITING date: 2022-12-07 date: 2025-05-26 date: 2025-08-04 date: 2024-03-15 date: 2024-03-18 name: Suzhou Genhouse Bio Co.,... |
This study is divided into two parts, namely the dose escalation phase I study and the dose expansion phase II study. conditions: Advanced Solid Tumors With MAPK Signal Pathway Mutant studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking... |
<|newrecord|> nctId: NCT06310369 id: EORTC 2335-GUCG briefTitle: Radiotherapy for BCG-unresponsive Non-muscle-invasive Carcinoma in Situ (CIS) Bladder Cancer overallStatus: NOT_YET_RECRUITING date: 2025-03-01 date: 2025-10-01 date: 2030-03-01 date: 2024-03-15 date: 2024-03-15 name: European Organisation for Research an... |
<|newrecord|> nctId: NCT06310356 id: CORDELIA briefTitle: Continuous Glucose Monitoring for Women With Gestational Diabetes acronym: CORDELIA overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2025-09 date: 2027-02 date: 2024-03-15 date: 2024-03-18 name: Universitaire Ziekenhuizen KU Leuven class: OTHER name: Univer... |
<|newrecord|> nctId: NCT06310343 id: 304993 briefTitle: ADAs to Alemtuzumab overallStatus: ACTIVE_NOT_RECRUITING date: 2022-04-25 date: 2025-11-30 date: 2025-11-30 date: 2024-03-15 date: 2024-03-15 name: Queen Mary University of London class: OTHER briefSummary: The main aim is to quantify the changes in alemtuzumab an... |
<|newrecord|> nctId: NCT06310330 id: 2019/1059 briefTitle: TRUST-ACE - Anticancer-treatment Cardiotoxicity Identification by Echocardiography acronym: TRUST-ACE overallStatus: RECRUITING date: 2024-03-08 date: 2026-12-31 date: 2026-12-31 date: 2024-03-15 date: 2024-03-20 name: Norwegian University of Science and Techno... |
Secondly, the study will evaluate whether novel tools used to improve standardization of recordings as well as automated measurements of central measurements, e.g. ejection fraction (EF) and global longitudinal strain (GLS) can improve the precision of echocardiography in daily clinical practice. conditions: Breast Neo... |
<|newrecord|> nctId: NCT06310317 id: CNR-IRIB-PRO-2024-003 briefTitle: Applied Behavior Analysis With Technologies overallStatus: RECRUITING date: 2023-09-01 date: 2025-01-31 date: 2025-01-31 date: 2024-03-15 date: 2024-03-15 name: Istituto per la Ricerca e l'Innovazione Biomedica class: OTHER briefSummary: Applied Beh... |
In this context, new approaches that attempt to integrate advanced technologies can play a key role. This experimental protocol aims to test whether the use of advanced technologies, such as tablets, as part of an intervention for a group of children with autism spectrum disorder (ASD) is more effective than the tradit... |
<|newrecord|> nctId: NCT06310304 id: INCB18424-153 briefTitle: A Study to Evaluate the Relative Bioavailability of Ruxolitinib Extended Release (XR) Tablets Compared With Ruxolitinib Immediate Release (IR) Tablets Administered Orally in Healthy Participants. overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-26 date: 2... |
<|newrecord|> nctId: NCT06310291 id: GLU001 briefTitle: VTP-1000 in Adults With Celiac Disease overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-08 date: 2025-08 date: 2024-03-15 date: 2024-03-15 name: Barinthus Biotherapeutics class: INDUSTRY briefSummary: GLU001 is a first-in-human clinical trial to assess t... |
<|newrecord|> nctId: NCT06310278 id: 1030312 briefTitle: Ossiview Normative Mobility Data Collection Protocol overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-10-31 date: 2024-10-31 date: 2024-03-15 date: 2024-03-15 name: Audioptics Medical Incorporated class: INDUSTRY briefSummary: The goal of this observ... |
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