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On the contrary, if the shock waves work on spasticity by indirectly acting on the nervous system's excitability, then a neurophysiology study could be used to preliminary identify the muscle groups with the most significant neurophysiological alterations, which could be the muscles benefitting the most from this treat... |
<|newrecord|> nctId: NCT06311513 id: 2023-1017 id: 1177535 type: OTHER_GRANT domain: Arthritis Foundation briefTitle: Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-12 date: 2028-12 date: 2024-03-15 date: 2024-03-15 name: Hospital for Special ... |
1. Investigational arm (Revision ACLR + cBMA) |
2. Control arm (Revision ACLR + Sham Incision) primaryPurpose: PREVENTION masking: SINGLE whoMasked: PARTICIPANT count: 40 type: ESTIMATED name: Concentrated Bone Marrow Aspirate Injection name: Sham Incision name: Revision Anterior Cruciate Ligament Reconstruction measure: Change from baseline in patient reported knee... |
<|newrecord|> nctId: NCT06311500 id: STUDY00151143 briefTitle: Sleep Health Enhancement in Midlife Adults overallStatus: RECRUITING date: 2024-02-13 date: 2025-06-30 date: 2025-06-30 date: 2024-03-15 date: 2024-03-15 name: University of Kansas Medical Center class: OTHER briefSummary: Despite the strong links between s... |
<|newrecord|> nctId: NCT06311487 id: 23-1388 id: 1R56DK136601-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R56DK136601-01 briefTitle: Time and Nutrient-Dependent Effects of Aerobic Exercise on Metabolism in Adults (TANDEM Study) acronym: TANDEM overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-08 d... |
<|newrecord|> nctId: NCT06311474 id: W81XWH-22-1-0250 briefTitle: Remote Assessment and Intervention for Behavior Problems in Kids With TSC acronym: RAINBOW overallStatus: RECRUITING date: 2022-08-01 date: 2025-04-30 date: 2025-07-31 date: 2024-03-15 date: 2024-03-15 name: University of California, Los Angeles class: O... |
<|newrecord|> nctId: NCT06311461 id: 22-001111 briefTitle: Effects of Acupuncture on Symptoms of Stable Angina acronym: EASE overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-12-31 date: 2027-06-30 date: 2024-03-15 date: 2024-03-15 name: University of California, Los Angeles class: OTHER name: University of... |
This study addresses the critical need to reduce persistent pain for angina. The investigators long-term goal is symptom management for diverse women and men with angina, targeting additional angina burden borne of social disadvantage |
Participants will be randomized to a 10-acupuncture session protocol, two treatments per week for five weeks, or an attention control group. Participants will view designated, non-pain related Technology, Entertainment, Design Talks equal to the time spent receiving acupuncture (\~7.5-10 hrs.). |
The investigators will test the efficacy of acupuncture for stable angina/chest pain syndrome to reduce pain and symptoms, improve health-related quality of life, reduce healthcare utilization and and improve patient related health outcomes. conditions: Angina, Stable studyType: INTERVENTIONAL phases: NA allocation: RA... |
<|newrecord|> nctId: NCT06311448 id: 10094 briefTitle: Personalized Targeted Immunomodulation in COVID-19 ARDS acronym: COMODULATE overallStatus: COMPLETED date: 2020-03-02 date: 2022-02-01 date: 2022-02-01 date: 2024-03-15 date: 2024-03-15 name: Erasmus Medical Center class: OTHER name: Amsterdam UMC name: Leiden Univ... |
Objectives: This project aims to identify a way to individualize and target immunomodulation, using COVID19 as a testcase for the future. |
* Identify immunological pathways which are associated with outcome in C-ARDS. |
* Test whether an individualized biomarker-based approach has an effect on outcome and costs when using single-target immunomodulation in C-ARDS(Tocilizumab, Anakinra, etc.). |
* Explore whether other immunological pathways were present in patients with C-ARDS which could have been intervened with medication which is already available and has been described in ARDS or similar diseases. |
Study type: Retrospective observational multicenter study in the Netherlands. |
Study population: Adult patients (≥ 18 years) hospitalized and admitted to the ICU with COVID-19 and acute respiratory distress syndrome (ARDS) (i.e., receiving invasive mechanical ventilation) will be included. |
Intervention (if applicable): Not applicable (retrospective study design). |
Nature and extent of the burden and risks associated with participation, benefit and group relatedness: Given the retrospective nature of the study, no burden, risks or benefits for the patient are associated with participation. The target population of this study is specific to hospitalized patients with COVID-19. con... |
<|newrecord|> nctId: NCT06311435 id: FBB-RNA-004 briefTitle: Utilizing Novel Blood RNA Biomarkers as a Diagnostic Tool in the Identification of Long COVID-19 overallStatus: RECRUITING date: 2024-03-15 date: 2026-03-15 date: 2026-03-15 date: 2024-03-15 date: 2024-03-15 name: MaxWell Clinic, PLC class: INDUSTRY briefSumm... |
<|newrecord|> nctId: NCT06311422 id: CAD/CAM-endocrown briefTitle: A 3-Year Clinical Evaluation Of Endocrown Restorations With Two Different Materials overallStatus: ACTIVE_NOT_RECRUITING date: 2020-03-15 date: 2023-03-15 date: 2028-09-15 date: 2024-03-15 date: 2024-03-19 name: Hacettepe University class: OTHER briefSu... |
<|newrecord|> nctId: NCT06311409 id: SMFS2019 briefTitle: Validation Study of the Speedy Meyer Fall Scale for Determining the Fall Risk of the Paediatric Patient overallStatus: RECRUITING date: 2020-01-29 date: 2024-03 date: 2024-04 date: 2024-03-15 date: 2024-03-15 name: Meyer Children's Hospital IRCCS class: OTHER br... |
The objective of this study is the validation of the new Humpty Dumpty Fall Scale defined as Speedy Meyer-Fall Scale (SMFS) by assessing the comprehension and validity of the scale and items via Content Validity Index (SCVI and ICVI) estimation of inter-item reliability (Crombach's alpha), inter-rater reliability (Cohe... |
<|newrecord|> nctId: NCT06311396 id: REVEAL briefTitle: Development of a Neuronal Microscope overallStatus: RECRUITING date: 2021-01-01 date: 2024-01-01 date: 2025-01-01 date: 2024-03-15 date: 2024-03-15 name: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico class: OTHER briefSummary: Hepatocellular carcinoma... |
<|newrecord|> nctId: NCT06311383 id: CLEE011ADE03 briefTitle: A Non-interventional Study for Women With HR-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer to Evaluate the Real-world Effectiveness of Treatment Algorithms Beginning With Ribociclib + AI/FUL, or With Endocrine Therapy or Chemotherapy a... |
<|newrecord|> nctId: NCT06311370 id: 2023-0100 briefTitle: Acceptability, Feasibility, and Development of an AI Driven, Multi-sensor, Non-invasive Digital Mental Health Platform in Children With ADHD and Emotional Symptoms overallStatus: COMPLETED date: 2023-08-09 date: 2024-02-05 date: 2024-02-05 date: 2024-03-15 date... |
<|newrecord|> nctId: NCT06311357 id: 100/2566 briefTitle: Percent Weight Change in the Medical Supplement Group of Early Breast Cancer overallStatus: RECRUITING date: 2023-07-12 date: 2024-04-26 date: 2024-04-30 date: 2024-03-15 date: 2024-03-15 name: Rajavithi Hospital class: OTHER_GOV briefSummary: The goal of this R... |
The main question is |
• the change of weight (%) before and after complete treatment of breast cancer therapy. |
Participants will be randomized into 2 group |
* intervention group - receive medical supplement daily during chemotherapy treatment. |
* control group - Nutritional advise during chemotherapy treatment. conditions: Early Stage Breast Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: INVESTIGATOR count: 40 type: ESTIMATED name: Ensure measure: Percen... |
<|newrecord|> nctId: NCT06311344 id: 2021-06 briefTitle: Filling Key Research Gaps With Clinical Implications in Mansonellosis and Schistosomiasis: a Network Approach overallStatus: RECRUITING date: 2021-04-14 date: 2024-03-31 date: 2024-03-31 date: 2024-03-15 date: 2024-03-15 name: IRCCS Sacro Cuore Don Calabria di Ne... |
<|newrecord|> nctId: NCT06311331 id: restor3d-007 briefTitle: Prospective Evaluation of Clinical and Radiographic Outcomes Following Total Talus Replacement (PROCLAIM) overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2031-05 date: 2031-05 date: 2024-03-15 date: 2024-03-15 name: Restor3D class: INDUSTRY briefSummar... |
<|newrecord|> nctId: NCT06311318 id: Department of surgery MED CMU briefTitle: Post-operative Lower Eyelid Massage for Prevention of the Lower Eyelid Scare Contracture After Subciliary Approach acronym: RCT overallStatus: COMPLETED date: 2016-11-01 date: 2019-11-30 date: 2020-09-30 date: 2024-03-15 date: 2024-03-15 nam... |
<|newrecord|> nctId: NCT06311305 id: Soh-med-24-03-07MS briefTitle: Does Early Laparoscopic Cholecystectomy After ERCP Reduce the Risk of Complications overallStatus: RECRUITING date: 2024-03-01 date: 2024-08-01 date: 2024-08-20 date: 2024-03-15 date: 2024-03-15 name: Sohag University class: OTHER briefSummary: Gallsto... |
The common mechanism of gallstone formation includes cholesterol hypersecretion, alteration in intestinal bile salt, cholesterol absorption and gall bladder hypokinesia, which leads to bile cholesterol supersaturation and nucleation. |
Incidence of CBD stones in cases of cholelithiasis is around 3.4%-15%.2 Choledocholithiasis can either be primary or secondary. Secondary Choledocholithiasis being more common occurs due to stones originating in gallbladder and then migrating through cystic duct to CBD. Primary bile duct stones originate from within bi... |
<|newrecord|> nctId: NCT06311292 id: STUDY22090138 briefTitle: Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis overallStatus: RECRUITING date: 2024-04 date: 2024-12 date: 2025-06 date: 2024-03-15 date: 2024-04-15 name: Daniel J. Weiner class: OTHER briefSummary: This is a small... |
Participants will use the Volara System during clinic visit in an attempt to produce sputum. conditions: Cystic Fibrosis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE maskingDescription: No parties will be prevented from having knowledge of the V... |
<|newrecord|> nctId: NCT06311279 id: Soh-Med-24-03-01MD briefTitle: End to End Versus Side to End Anastomosis After Anterior Resection of Cancer Rectum overallStatus: RECRUITING date: 2024-03-05 date: 2025-01-01 date: 2025-03-20 date: 2024-03-15 date: 2024-03-15 name: Sohag University class: OTHER briefSummary: Compari... |
<|newrecord|> nctId: NCT06311266 id: 34-424 ex 21/22 briefTitle: Robotic Endoscopic Neurosurgical Interventions acronym: RENI overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2025-03 date: 2025-10 date: 2024-03-15 date: 2024-03-15 name: Medical University of Graz class: OTHER briefSummary: Endoscopic operations... |
The EndoGuide robot is a modular positioning device for controlling endoscopic instruments, which can use radiological data from neuronavigation to align the trajectory in real time with an accuracy of \<0.1mm. |
The previous model of the robot is currently approved for interventional radiology and positioning of electrodes and catheters in the field of neurosurgery and is now to be tested in endoscopic neurosurgery. |
The investigators therefore expect not only an increase in the accuracy of endoscopic interventions, but also a reduction in morbidity. conditions: Robot for Endoscopic Neurosurgical Interventions studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: prosp... |
<|newrecord|> nctId: NCT06311253 id: 2024-LACTOFERRINPREGNANT briefTitle: Non-surgical Periodontal Treatment With Adjunctive Use of Lactoferrin Contained in Toothpaste and Mouthwash overallStatus: ENROLLING_BY_INVITATION date: 2024-03-20 date: 2024-11 date: 2024-11 date: 2024-03-15 date: 2024-04-26 name: University of ... |
<|newrecord|> nctId: NCT06311240 id: 02-24-108-003 briefTitle: Chronic Pain in Patients in Hemodialysis acronym: DolERC overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-06 date: 2024-09 date: 2024-03-15 date: 2024-03-15 name: Cardenal Herrera University class: OTHER name: Consorci Sanitari de Terrassa briefSu... |
The aim of this study is to assess the presence and characteristics of chronic pain in patients with ESRD undergoing hemodialysis to determine whether it is relevant to include the management of chronic pain in the holistic treatment (physical activity, nutrition, and psychological support) already being implemented in... |
<|newrecord|> nctId: NCT06311227 id: NCI-2024-01904 id: NCI-2024-01904 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: 10637 type: OTHER domain: National Cancer Institute LAO id: 10637 type: OTHER domain: CTEP briefTitle: Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia over... |
<|newrecord|> nctId: NCT06311214 id: NCI-2024-01903 id: NCI-2024-01903 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: 10397 type: OTHER domain: University of Texas MD Anderson Cancer Center LAO id: 10397 type: OTHER domain: CTEP id: UM1CA186688 type: NIH link: https://reporter.nih.gov/quickSearch/UM... |
<|newrecord|> nctId: NCT06311201 id: P.T.REC/012/004256 briefTitle: Effect of Pilates Exercises on Diastasis Recti Abdominis in Postpartum Women overallStatus: COMPLETED date: 2023-09-26 date: 2024-01-26 date: 2024-01-26 date: 2024-03-15 date: 2024-03-19 name: Cairo University class: OTHER briefSummary: The purpose of ... |
<|newrecord|> nctId: NCT06311188 id: HUM00240243 id: 1R21MD016940-01A1 type: NIH link: https://reporter.nih.gov/quickSearch/1R21MD016940-01A1 briefTitle: Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness overallStatus: NOT_YET_RECRUITING date: 2024-04-14 date: 2024-11-30 date: 2025-01-31 date: 2024-03-1... |
<|newrecord|> nctId: NCT06311175 id: H20-0114 briefTitle: Diet Tracking Prescriptions for Weight Loss overallStatus: RECRUITING date: 2024-04-30 date: 2024-05-31 date: 2024-09-01 date: 2024-03-15 date: 2024-04-25 name: University of Connecticut class: OTHER briefSummary: Lifestyle interventions are effective at produci... |
<|newrecord|> nctId: NCT06311162 id: 2023-01615 briefTitle: Early Life Intervention in Pediatrics Supported by E-health - SMOKE acronym: ELIPSE-II overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2027-08-31 date: 2028-07-31 date: 2024-03-15 date: 2024-03-20 name: Insel Gruppe AG, University Hospital Bern class:... |
<|newrecord|> nctId: NCT06311149 id: 479/2023/Oss/AOUFe briefTitle: Multicenter Evaluation of Patients Using LATITUDE Monitoring System acronym: Multitude overallStatus: RECRUITING date: 2023-12-01 date: 2043-12-31 date: 2043-12-31 date: 2024-03-15 date: 2024-03-15 name: University Hospital of Ferrara class: OTHER brie... |
The registry is designed to constitute a shared environment for the collection, management, analysis and reporting of clinical and diagnostic data, adopted by a network of European scientifically-motivated physicians who use rhythm management diagnostic and therapeutic solutions from Boston Scientific in their clinical... |
The Multitude study will facilitate the sharing of scientific proposals within a large network of researchers, and it will allow researchers to record the experience with medical devices throughout the device and patient lifecycle. conditions: Cardiovascular Diseases conditions: Arrhythmias, Cardiac conditions: Heart F... |
<|newrecord|> nctId: NCT06311136 id: PEAK briefTitle: Effectiveness of an Ecological Momentary Emotion Regulation Intervention overallStatus: RECRUITING date: 2024-01-12 date: 2024-12 date: 2024-12 date: 2024-03-15 date: 2024-03-18 name: Heidelberg University class: OTHER briefSummary: This two-armed randomized control... |
Participants will be randomly assigned to either the intervention group, receiving a valence-specific emotion regulation intervention in daily life, or a monitoring-only control group. The valence-specific intervention supports the implementation of different emotion regulation strategies based on whether a person is e... |
Outcome measures include emotion regulation ability, self-efficacy, and strategy use, depressive symptoms, positive and negative affect, and emotion beliefs (controllability, usefulness). |
A second aim of the study is to compare beliefs about positive emotions and strategies to regulate them between individuals with and without current depressive disorders. Furthermore, the investigators aim to examine why individuals might choose unfavorable emotion regulation strategies even when feeling good. Therefor... |
Clinical interviews will be conducted blindly. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 200 type: ESTIMATED name: Valence-Specific Ecological Momentary Intervention measure: Emotion Regulation Ability (Positive, Negative Emotions) measure: Emotion Regulation Self-Efficacy for Positive and Negative Emo... |
<|newrecord|> nctId: NCT06311123 id: ISR IM047-059 briefTitle: Understanding Ozanimod's MOA Via Mass Cytometry in Ulcerative Colitis overallStatus: RECRUITING date: 2023-10-06 date: 2026-09-30 date: 2026-09-30 date: 2024-03-15 date: 2024-03-15 name: University of California, San Diego class: OTHER briefSummary: The goa... |
1. Prospectively assess the effects of ozanimod on the cellular composition of intestinal lamina propria and blood by deep immunophenotyping (CyTOF) of immune cell subsets prior and after the drug's administration. |
2. Determine whether changes in cell subsets observed via mass cytometry correlate with with clinical or histologic parameters of disease activity. |
Colonic biopsies and peripheral blood samples will be collected from patients with UC before and after the onset of ozanimod. |
Researchers will compare intestinal and peripheral leukocytes before and after the drug's administration. conditions: Ulcerative Colitis conditions: Ulcerative Colitis Chronic Moderate studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 10 type: ESTIMATED measure: difference in leuko... |
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