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<|newrecord|> nctId: NCT06293235 id: 2024/2120 briefTitle: Towards Optimal Fertility, Fathering and Fatherhood studY acronym: TOFFFY overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2026-06 date: 2027-03 date: 2024-03-05 date: 2024-03-05 name: KK Women's and Children's Hospital class: OTHER_GOV briefSummary: This ... |
<|newrecord|> nctId: NCT06293222 id: SCD Support briefTitle: Patient and Public Involvement and Engagement in Research With Children and Young People With Sickle Cell Disorder and Their Families overallStatus: ACTIVE_NOT_RECRUITING date: 2023-08-21 date: 2024-04-30 date: 2024-04-30 date: 2024-03-05 date: 2024-03-07 nam... |
Methods: Workshops with a) members of a patient advocacy organisation (Sickle Cell Society n=5) b): i) Children and young people (10-18 years) with sickle cell disorder (n=15) and ii) their siblings (10-18 years, n=10) and iii) their parents (n=15), c) Researchers form the Cicely Saunders Institute Outputs: Resources t... |
<|newrecord|> nctId: NCT06293209 id: Sunpasitthiprasong Hospital id: Sunpasitthiprasong Hospital type: OTHER domain: Sunpasitthiprasong Hospital briefTitle: Effect of Cool Spray and Cold Packs in Reducing Preoperative Edema and Pain in Ankle Fractures in Ubonratchathani acronym: 3-armRCT overallStatus: ACTIVE_NOT_RECRU... |
The purpose of this study is to compare the efficacy of evaporative coolants with that of ice packs in the preoperative management of edema and pain in patients with an ankle fracture conditions: Ankle Fractures conditions: Swelling conditions: Cryotherapy Effect studyType: INTERVENTIONAL phases: NA allocation: RANDOMI... |
The sample group comprises 30 patients admitted for treatment in the male orthopedic surgery department, female orthopedic surgery department, and accident orthopedic surgery department at Sunpasitthiprasong Hospital, Ubon Ratchathani from August 2023 to January 2024. . primaryPurpose: TREATMENT masking: DOUBLE whoMask... |
<|newrecord|> nctId: NCT06293196 id: 20231107 briefTitle: Effects of Acupoint Massage Around Eyes on Ocular Biological Indexes overallStatus: RECRUITING date: 2023-09-01 date: 2024-03-31 date: 2025-06-30 date: 2024-03-05 date: 2024-03-05 name: Zhongnan Hospital class: OTHER briefSummary: This study aims to investigate ... |
<|newrecord|> nctId: NCT06293183 id: EGE-HEM-STO-01 briefTitle: The Effect of Artificial Intelligence Supported Mobile Learning on Nutrition/Hydration Control and Individual Management overallStatus: NOT_YET_RECRUITING date: 2024-04-04 date: 2024-09-30 date: 2024-12-30 date: 2024-03-05 date: 2024-03-05 name: Ege Univer... |
This research aims to investigate the impact of an artificial intelligence-supported mobile application developed for HD patients on the control of nutrition/fluid intake and individual management. conditions: Cronich Kidney Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL... |
<|newrecord|> nctId: NCT06293170 id: 2024-DETECTIVENEUROLOGYUKD0001 briefTitle: Automated Screening for Clinically Ascertained Loss of Cerebral Functions acronym: DETECT-IVE overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-11-01 date: 2026-11-01 date: 2024-03-05 date: 2024-03-05 name: Technische Universitä... |
Objective: The objective of the study is to evaluate the effectiveness of an automated digital screening tool in the identification of patients with severe brain damage who are at risk of impending ILBF compared to standard practice without digital support. |
Study design: Stepped-Wedge, multicenter, cluster-randomized, controlled trial |
Study population: The study includes patients aged 18 years or older with primary and/or secondary acute brain damage, requiring mechanical ventilation, and who are deceased upon hospital discharge. |
Intervention: DETECT periodically processes real-time data from the corresponding electronic medical record system to screen for a combination of coma, indicated by a Richmond Agitation Sedation Scale (RASS) score of - 4 or - 5 or Glasgow Coma Scale (GCS) score of 6-3, along with manually assessed absence of bilateral ... |
Primary study endpoint: The primary endpoint is the identification of patients who eventually develop ILBF during hospitalization. |
Secondary study endpoints: Secondary outcomes encompass the missed identification of potential ILBF cases (as retrospectively classified) and the rate of deceased organ donations. Upon completion of the study, a survey will be conducted to investigate the stakeholders' experiences with DETECT. conditions: Irreversible ... |
<|newrecord|> nctId: NCT06293157 id: 2023/ABM/01/00013 briefTitle: Carbon Fiber Transpedicular Screws in Treatment of Spinal Metastatic Disease overallStatus: RECRUITING date: 2023-12-01 date: 2028-12-31 date: 2033-12-31 date: 2024-03-05 date: 2024-03-05 name: Copernicus Memorial Hospital class: OTHER name: Medical Res... |
Study plan: The open, three-arm, prospective randomized study is planned to involve 226 patients with metastatic disease of the spine, with a known or undiagnosed primary site. Patients will be qualified for 2 types of interventions. The first one includes treatment with stereotactic radiotherapy (SBRT) in the first st... |
Study population: The study includes adult patients with metastatic spine disease, with a known or unknown primary tumor, qualified for SBRT and surgical treatment. |
Assumed effects: It is assumed that the treatment proposed in the project would extend progression free survival by several months or achieve local control in an additional 5% of patients. Moreover, by improving the quality of imaging, earlier diagnosis of local recurrences and implementation of appropriate locoregiona... |
<|newrecord|> nctId: NCT06293144 id: yuewei20231129 briefTitle: the 95% Effective Dose of Ciprofol for Adjunctive Sedation Undergoing Knee Arthroplasty in Elderly People overallStatus: RECRUITING date: 2023-11-29 date: 2024-05 date: 2024-05 date: 2024-03-05 date: 2024-03-05 name: Second Hospital of Shanxi Medical Unive... |
<|newrecord|> nctId: NCT06293131 id: yuewei20230705 briefTitle: Median Effective Dose of Ciprofol-Assisted Sedation for Elderly Patients Undergoing Knee Arthroplasty overallStatus: COMPLETED date: 2023-05-29 date: 2023-09-28 date: 2023-09-28 date: 2024-03-05 date: 2024-03-05 name: Second Hospital of Shanxi Medical Univ... |
<|newrecord|> nctId: NCT06293118 id: 71055423.3.0000.0071 briefTitle: The Effects of Ischemic Conditioning in Individuals With Parkinson's Disease overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2028-01-15 date: 2024-03-05 date: 2024-03-05 name: Hospital Israelita Albert Einstein class: OTHER ... |
2. control group (Sham) primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Patients were unaware of the allocation. whoMasked: PARTICIPANT count: 34 type: ESTIMATED name: Ischemic conditioning group name: Sham group measure: Motor function measure: Cognitive performance measure: PDQ-39 measure: Timed up and ... |
<|newrecord|> nctId: NCT06293105 id: MR/T040688/1 briefTitle: Social Responses to Stigma overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-01-31 date: 2025-01-31 date: 2024-03-05 date: 2024-03-05 name: King's College London class: OTHER name: Groundswell name: Lambeth Service Users Council name: Museum of H... |
The methodology is an ethnographic case study of the south London care and support system and its social context. The study will use a range of methods for data collection: interviews with people who are homeless, delivery stakeholders, and policy makers; a survey of peoples' experiences; observation within selected ca... |
The study will be implemented through two parallel studies. The first, with KCL-REMAS approval, will operate in non-NHS sites. The second, with NHS-IRAS approval, will operate in NHS sites. The protocols are aligned with adaptations for each type of site. |
A linked method to develop theory is cross-case comparison between South London and Vancouver, Canada, through secondary data analysis to linked studies ongoing there. The study will be ongoing from 2022 until January 2025. The project is funded in two phases, with potential to extend the study by a further three years... |
The results of the study will inform the design of a novel intervention strategy to address the social dimensions of stigma. Subject to additional funding applications, the intervention strategy will be piloted and evaluated from 2025 onwards. The study results will be disseminated through scientific publications, publ... |
<|newrecord|> nctId: NCT06293092 id: P.T.REC/012/004008 briefTitle: Effect of Intradialytic Exercises in Chronic Kidney Disease Patients overallStatus: COMPLETED date: 2022-04-30 date: 2023-10-30 date: 2024-01-30 date: 2024-03-05 date: 2024-03-05 name: Cairo University class: OTHER briefSummary: the purpose of this stu... |
<|newrecord|> nctId: NCT06293079 id: BiruniUnive id: Researcher type: OTHER domain: Biruni University briefTitle: The Effect of Hybrid Telerehabilitation-Based Structured Exercise Programs in Patients With Multiple Sclerosis overallStatus: RECRUITING date: 2023-08-30 date: 2024-02-12 date: 2024-08-30 date: 2024-03-05 d... |
<|newrecord|> nctId: NCT06293066 id: KCH23-257 briefTitle: Performance of Ultrasound in Women With Postmenopausal or Abnormal Uterine Bleeding Between White and Black Ethnic Groups- a Retrospective Cohort Study. overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-31 date: 2024-03-01 date: 2024-03-01 date: 2024-03-05 dat... |
To assess whether there is a higher incidence of uninformative ultrasound in black vs white women conditions: Postmenopausal Bleeding conditions: Endometrial Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 330 type: ACTUAL name: Ultrasound measure: To assess whether ther... |
<|newrecord|> nctId: NCT06293053 id: PKM17836 id: U1111-1287-7255 type: REGISTRY domain: ICTRP briefTitle: A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥6 Months to <18 Years of Age With Prurigo Nodularis overallStatus: NOT_YET_RECRUITING date: 2024-02-28 date: 2027-10-28 date: 20... |
The study consists of 3 periods: |
* Screening period: 2 to 4 weeks. |
* Treatment period: 24 weeks. |
* Post-intervention follow-up period: 16 weeks. The study duration will be approximately 42 to 44 weeks for each participant (including screening, treatment, and follow-up periods). |
The total number of planned study visits for each participant will be 6. conditions: Prurigo Nodularis studyType: INTERVENTIONAL phases: PHASE3 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 18 type: ESTIMATED name: Dupilumab measure: Concentration of dupilumab in serum me... |
<|newrecord|> nctId: NCT06293040 id: IRB00434441 id: R01DA052295 type: NIH link: https://reporter.nih.gov/quickSearch/R01DA052295 briefTitle: Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2027-06 date: 2027-12 date: 2024-03-05 date... |
<|newrecord|> nctId: NCT06293027 id: IMAGINER FXS briefTitle: Optical Imaging as a Tool for Monitoring Brain Function in Fragile X Syndrome overallStatus: RECRUITING date: 2023-06-01 date: 2025-06-15 date: 2025-12-15 date: 2024-03-05 date: 2024-03-05 name: IRCCS Fondazione Stella Maris class: OTHER briefSummary: The ob... |
<|newrecord|> nctId: NCT06293014 id: QLMA-CRC-IIT-001 briefTitle: TAS-102 Combined With Bevacizumab for Second-line Maintenance Treatment of Advanced Colorectal Cancer overallStatus: RECRUITING date: 2024-02-23 date: 2025-10-15 date: 2026-11-28 date: 2024-03-05 date: 2024-03-05 name: Henan Cancer Hospital class: OTHER_... |
<|newrecord|> nctId: NCT06293001 id: SBA 23/349 briefTitle: Cross-Cultural Adaptation, Validity and Reliability of the Turkish Version of the ADAP Shoulder Scale overallStatus: RECRUITING date: 2023-11-28 date: 2024-04-26 date: 2024-04-26 date: 2024-03-05 date: 2024-04-29 name: Hacettepe University class: OTHER briefSu... |
Until now, pain-related fear and avoidance behaviours in patients with shoulder pain have been evaluated with the Tampa Kinesiophobia Scale, Pain Avoidance Beliefs Scale and Fear of Pain Scale. However, only patients with low back pain were included in the development of these scales. There was no scale developed speci... |
The aim of our study was to perform cross-cultural adaptation, validity and reliability of the Turkish version of the Avoidance of Daily Activities Photo Scale for Patients with Shoulder Pain (ADAP Shoulder Scale). conditions: Questionnaire conditions: Shoulder Pain conditions: Validity conditions: Reliability studyTyp... |
<|newrecord|> nctId: NCT06292988 id: MYELO briefTitle: Predictive Factors for Medullary Thyroid Cancer Aggressiveness acronym: MYELO overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-04-15 date: 2024-04-15 date: 2024-03-05 date: 2024-03-05 name: Aristotle University Of Thessaloniki class: OTHER briefSummary... |
<|newrecord|> nctId: NCT06292975 id: RS210 - 326709 briefTitle: Exercise for Improving Radiotherapy Efficacy in Rectal Cancer overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-02 date: 2026-02 date: 2024-03-05 date: 2024-04-24 name: University of Hull class: OTHER name: Hull University Teaching Hospitals NHS T... |
<|newrecord|> nctId: NCT06292962 id: SH-34988389 briefTitle: Evaluating the Impact of Vagus Nerve Stimulation on Diabetic Peripheral Neuropathic Pain acronym: VNSDPN overallStatus: COMPLETED date: 2023-10-01 date: 2024-03-01 date: 2024-03-03 date: 2024-03-05 date: 2024-04-22 name: Saima Abass Tahammal class: OTHER name... |
<|newrecord|> nctId: NCT06292949 id: TJ-IRB20230956 briefTitle: Clinical Study of Resistant Starch in Improving Constipation overallStatus: RECRUITING date: 2023-09-27 date: 2024-09-25 date: 2024-09-25 date: 2024-03-05 date: 2024-03-05 name: Huaping Xie class: OTHER briefSummary: Constipation is one of the most common ... |
<|newrecord|> nctId: NCT06292936 id: 30692 briefTitle: RemI for Post-Bariatric Surgery Weight Regain overallStatus: NOT_YET_RECRUITING date: 2024-03-04 date: 2027-12-31 date: 2028-04-01 date: 2024-03-05 date: 2024-03-05 name: Temple University class: OTHER name: Rush University briefSummary: The goal of this clinical t... |
The main research aims are: |
1. To compare changes in body weight over 12 months in 200 bariatric patients who have regained \> 5% of their weight and are randomly assigned to ABTi or Control. |
2. To compare changes in eating behaviors (i.e., caloric intake, frequency of maladaptive eating behaviors), physical activity, and weight-related comorbidities (i.e., biomarkers of diabetes, hypertension) over 12 months in the two groups. |
3. Exploratory - To test ABTi's theoretical mechanisms of action, including a) effects of theory-based active ingredients (i.e., acceptance, defusion, values clarity, mindfulness) on weight outcomes and b) changes in impact of internal states (i.e., hunger, cravings) on eating behavior. conditions: Obesity conditions: ... |
<|newrecord|> nctId: NCT06292923 id: TILS-021 briefTitle: A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients overallStatus: RECRUITING date: 2023-11-15 date: 2024-11 date: 2024-11 date: 2024-03-05 date: 2024-03-19 name: Tiziana Life Sciences LTD class: INDUSTRY briefSummary: Fora... |
The goal of this Phase 2a, randomized, double-blind placebo-controlled, multicenter dose-ranging study is to evaluate the use of nasal foralumab in patients with non-active secondary progressive multiple sclerosis (SPMS). |
The primary objectives that this study aims to answer are: |
1. To determine the safety and tolerability of 50 μg/dose and 100 μg/dose of foralumab nasal compared to placebo |
2. To investigate the effect of foralumab relative to placebo on the change from baseline \[18F\]PBR06-positron emission tomography (PET) scans for microglial activation, after 12 weeks (3) months of study treatment. conditions: Secondary Progressive Multiple Sclerosis studyType: INTERVENTIONAL phases: PHASE2 allocatio... |
<|newrecord|> nctId: NCT06292910 id: REC 64-299-1-1 briefTitle: Central Venous to Arterial CO2 Difference and Low Cardiac Output Syndrome Related Outcomes in Children After Cardiac Surgery acronym: VACO2 overallStatus: COMPLETED date: 2021-08-08 date: 2023-12-21 date: 2023-12-26 date: 2024-03-05 date: 2024-03-05 name: ... |
The main questions is which one is the best prognostication for post operation poor outcomes Participants will be taken routine blood test for post cardiac care (at ICU arrival, 6, 12, and 24 hour post operation) and follow the their outcomes. There is no any intervention or drug in this research conditions: Congenital... |
<|newrecord|> nctId: NCT06292897 id: 3312 briefTitle: Using Tissue-based Spatial Data to Understand How Obesity-related Tumor Metabolites Fuel Prostate Cancer Progression acronym: OBESITA'&PCa overallStatus: RECRUITING date: 2023-03-20 date: 2026-09-15 date: 2027-01-15 date: 2024-03-05 date: 2024-03-05 name: Fondazione... |
ii. Characterize the immune infiltrate in the prostate carcinoma of the aforementioned patients. |
iii. Assess the association between intra-tumoral lactate accumulation (using LDHA and MCT-4 protein expression levels as readouts) and alterations in the tumor immune microenvironment and/or deregulation of relevant oncogenic pathways. conditions: Prostate Cancer conditions: Prostate Adenocarcinoma conditions: Prostat... |
<|newrecord|> nctId: NCT06292884 id: IMAGINER CREATINE briefTitle: Optical Imaging as a Tool for Monitoring Brain Function in Creatine Deficiency Syndromes overallStatus: RECRUITING date: 2023-10-06 date: 2025-06-15 date: 2025-12-15 date: 2024-03-05 date: 2024-03-05 name: IRCCS Fondazione Stella Maris class: OTHER brie... |
<|newrecord|> nctId: NCT06292871 id: 2023/2712 briefTitle: The Use of Social Media Platform to Continuously Support Pregnant Women With Gestational Diabetes Mellitus overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-06 date: 2025-05 date: 2024-03-05 date: 2024-03-05 name: KK Women's and Children's Hospital cla... |
i. To measure the participants' acceptability and satisfaction levels of receiving intervention through the social media platform. |
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