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1028 patients will be randomly allocated to receive either the standard therapy or Trelegy and will be monitored by the investigators for 1 year in 2 on-site visits + 2 remote visits. conditions: Chronic Obstructive Pulmonary Disease studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PAR... |
<|newrecord|> nctId: NCT06282848 id: HongKongPU_Optometry4 briefTitle: Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate overallStatus: RECRUITING date: 2024-01-01 date: 2026-12 date: 2026-12 date: 2024-02-28 date: 2024-03-07 name: The Hong Kong Polyt... |
* the effectiveness of using 0.05% atropine and prescribing DIMS lens for myopia control in children with different myopia progression rates |
* the contribution of L/M cones in juvenile myopia progression and changes of retinal activities under atropine and DIMS treatment. |
Participants will have baseline and follow-up eye examinations and given either pharmacological treatment with 0.05% atropine or non-pharmacological treatment with DIMS lens for myopia control. |
Researchers will compare the changes of refractive errors and axial length after different types of interventions and investigate the relations between the parameters of mfERG responses and the thicknesses of retinal layers and choroid. conditions: Myopia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED inte... |
<|newrecord|> nctId: NCT06282835 id: 2023KY242 briefTitle: Eravacycline Combination Therapy for MRAB overallStatus: RECRUITING date: 2024-01-26 date: 2024-10-31 date: 2024-12-31 date: 2024-02-28 date: 2024-02-28 name: Fujian Medical University Union Hospital class: OTHER briefSummary: The goal of this observational stu... |
Participants will be given Eravacycline and Polymyxin，or other antibiotcs that the Investigator considered suitable. During the clinical trial, participants will be monitored for blood drug concentrations and drug concentrations in the ELF (Epithelial Lining Fluid。Clinical efficacy rate and microbiological clearance ra... |
<|newrecord|> nctId: NCT06282822 id: HFpEF-SWE briefTitle: Shear Wave Elastography for Diagnosis of Heart Failure With Preserved Ejection Fraction overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-10-31 date: 2025-03-01 date: 2024-02-28 date: 2024-02-28 name: First Hospital of China Medical University class... |
<|newrecord|> nctId: NCT06282809 id: CSP3325 briefTitle: The HistoSonics Edison™ System for Treatment of Pancreatic Adenocarcinoma Using Histotripsy acronym: GANNON overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-07 date: 2026-01 date: 2024-02-28 date: 2024-04-11 name: HistoSonics, Inc. class: INDUSTRY brief... |
<|newrecord|> nctId: NCT06282796 id: EPW-CABC-01 briefTitle: Early Prediction and Warning for Cardiotoxicity Due to Anthracycline-Based Breast Cancer Chemotherapy overallStatus: RECRUITING date: 2024-01-01 date: 2026-12-31 date: 2028-12-31 date: 2024-02-28 date: 2024-02-28 name: First Hospital of China Medical Universi... |
<|newrecord|> nctId: NCT06282783 id: 2024-511532-27-00 briefTitle: Studying Topiramate for Re-Activating the HIV-1 Reservoir acronym: STAR overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2025-04 date: 2025-08 date: 2024-02-28 date: 2024-02-28 name: Erasmus Medical Center class: OTHER briefSummary: Even with curre... |
So far, the drugs tested can find the virus, but they don't get rid of it completely. That's why there need to be new drugs that can do this more effectively. The Erasmus MC HIV Eradication Group (EHEG) has been testing new drugs in the lab and found a drug called topiramate can wake up the virus without harming the ce... |
Most of the people that participate in HIV cure studies are men, even though most people living with HIV around the world are women. Previous research has shown that men and women might respond differently to these treatments. So, in this study, topiramate will be investigated in both men and women. This could help us ... |
<|newrecord|> nctId: NCT06282770 id: IRB#23-000444 briefTitle: Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery overallStatus: RECRUITING date: 2023-07-01 date: 2024-07-01 date: 2025-07-01 date: 2024-02-28 date: 2024-02-28 name: University of California, Los Angeles class: OTHER brief... |
Many possible treatment plans have been incorporated to assist the patient with recovery - notably medications, physical therapy, and braces. However, few studies have looked at laser diodes that utilize high-power laser lights that are aimed at decreasing pain and inflammation. Investigators aim to look compare patien... |
<|newrecord|> nctId: NCT06282757 id: 202302 briefTitle: Physiotherapists' Placebo or Nocebo Communication Regarding VR in CMP overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-05-01 date: 2024-05-01 date: 2024-02-28 date: 2024-03-07 name: HAN University of Applied Sciences class: OTHER briefSummary: Rationa... |
Objective: To determine the effect of physiotherapists' placebo or nocebo therapeutic communication about VR, on treatment credibility and expectation in patients with CMP |
Study design: Web-based randomized controlled trial. |
Study population: 100 participants |
Intervention: The placebo intervention group will be shown an educational video about VR, containing placebo effects enhancing verbal language. The nocebo intervention group will be shown an educational video about VR, containing nocebo effects enhancing verbal language. |
Primary study parameters: The primary study parameters are treatment credibility and treatment expectation. Treatment credibility and treatment expectations will be measured using the Dutch credibility and expectancy questionnaire (CEQ). conditions: Communication conditions: Chronic Pain studyType: INTERVENTIONAL phase... |
<|newrecord|> nctId: NCT06282744 id: OPTIMAL Arabic version briefTitle: Cross Cultural Adaptation, Validity and Reliability Test of the Arabic Version of the Outpatient Physical Therapy Improvement in Movement Assessment Log acronym: OPTIMAL overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-03 date: 2024-04... |
To translate, culturally adapt, and to test the validity and reliability of the Outpatient Physical Therapy Improvement in Movement Assessment Log in Arabic speaking language. conditions: Physical Performance conditions: Outpatients studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL cou... |
<|newrecord|> nctId: NCT06282731 id: ECKIRB1020407 briefTitle: The Changes of Urine Growth Factors Level overallStatus: COMPLETED date: 2013-05-31 date: 2016-09-01 date: 2017-04-27 date: 2024-02-28 date: 2024-02-28 name: En Chu Kong Hospital class: OTHER briefSummary: The Changes of Urine Growth Factors Level in Patien... |
<|newrecord|> nctId: NCT06282718 id: POS-ARI-PC CORE and AUDIT id: 965313 type: OTHER_GRANT domain: European Union id: 10204126 type: REGISTRY domain: ISRCTN id: 55487 type: OTHER domain: NIHR CPMS id: 324504 type: OTHER domain: IRAS briefTitle: A Long-term Observational Study Evaluating the Presentation and Management... |
<|newrecord|> nctId: NCT06282705 id: 306347 briefTitle: Dose Response Effect of Drop Jumps on Bone Characteristics overallStatus: COMPLETED date: 2023-01-06 date: 2023-12-13 date: 2023-12-13 date: 2024-02-28 date: 2024-02-28 name: Nottingham Trent University class: OTHER briefSummary: The study aims to assess if a 16-w... |
The present study aims to use varied drop jump heights to identify an osteogenic dose response effect. Drop jumps have been previously used to expose osteogenic effects in research due to the load produced at impact. Is it possible to identify an optimum height for bone response during impact? If so do we then find any... |
<|newrecord|> nctId: NCT06282692 id: UNAIR-MP-INAKTIF-R-005 briefTitle: INAVAC Vaccine Phase III (Immunobridging Study) in Healthy Population Aged 12 to 17 Years Old overallStatus: RECRUITING date: 2023-06-19 date: 2024-05-19 date: 2024-07-19 date: 2024-02-28 date: 2024-02-28 name: Dr. Soetomo General Hospital class: O... |
INAVAC is an inactivated vaccine made of SARS-CoV-2 virus isolated from a patient in Surabaya, composed with aluminium hydroxy gel, tween 80, and L-histidine, and this study will be the first phase III in adolescents. conditions: COVID-19 Pandemic conditions: COVID-19 Vaccines studyType: INTERVENTIONAL phases: PHASE3 a... |
The vaccine will be administered with 2-dose schedule, intramuscularly, with 28 day interval. count: 400 type: ESTIMATED name: INAVAC (Vaksin Merah Putih - UA-SARS CoV-2 (Vero Cell Inactivated) 5 µg measure: Vaccine Neutralizing Antibody Profile measure: Incidence of Adverse Events measure: Humoral Immunogenicity - The... |
<|newrecord|> nctId: NCT06282679 id: KY20220701-03 briefTitle: Clinical Observation of Botulinum Toxin A Treatment in the Treatment of Rosacea overallStatus: RECRUITING date: 2022-04-01 date: 2024-03-01 date: 2024-06-28 date: 2024-02-28 date: 2024-02-28 name: Nanjing First Hospital, Nanjing Medical University class: OT... |
<|newrecord|> nctId: NCT06282666 id: KE-0254/150/2019 briefTitle: Lumbar ESPB in Hip Replacement Surgery acronym: ESPB_HIP overallStatus: NOT_YET_RECRUITING date: 2024-02-19 date: 2025-02-01 date: 2025-08-01 date: 2024-02-28 date: 2024-02-28 name: Medical University of Lublin class: OTHER briefSummary: In this study, c... |
Physiotherapists assessing outcomes will not be aware of patient allocation. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Spinal anesthesia name: lumbar erector spinae plane block name: Epidural analgesia name: patient-controlled analgesia name: Timed Up a... |
<|newrecord|> nctId: NCT06282653 id: Endo-ergonomics briefTitle: Postural and Muscle Fatigue Analysis of Endodontic Residents overallStatus: RECRUITING date: 2024-04-30 date: 2025-06-30 date: 2025-11-01 date: 2024-02-28 date: 2024-02-28 name: Universidad Europea de Madrid class: OTHER briefSummary: Musculoskeletal diso... |
<|newrecord|> nctId: NCT06282640 id: 567 briefTitle: Comparıson Of Electromyography Results Before And After Vıtamın D Treatment In Patıents Wıth Carpal Tunnel Syndrome overallStatus: COMPLETED date: 2021-12-30 date: 2022-06-30 date: 2022-08-30 date: 2024-02-28 date: 2024-02-28 name: Dr. Ayşe Güç class: OTHER_GOV name:... |
<|newrecord|> nctId: NCT06282627 id: 10430012010023 briefTitle: The COVID HOME Study: Prospective Cohort Study of Non-hospitalised COVID-19 Patients acronym: COVID-HOME overallStatus: COMPLETED date: 2020-03-20 date: 2022-07-30 date: 2022-08-30 date: 2024-02-28 date: 2024-02-28 name: University Medical Center Groningen... |
The COVID HOME study conducts research among COVID-19 patients and their family members who were not hospitalised during acute disease, to guide patient care and inform public health guidelines for infection prevention and control in the community and household. |
Methods. An ongoing prospective longitudinal observational study of COVID-19 outpatients was established in March 2020 at the beginning of the COVID-19 pandemic in the Netherlands. Laboratory confirmed SARS-CoV-2 infected individuals of all ages that did not merit hospitalisation, and their household (HH) members, were... |
<|newrecord|> nctId: NCT06282614 id: MUCO245 id: 2023-A02081-44 type: OTHER domain: ID-RCB briefTitle: Performance and Safety of MUCOGYNE® Ovule as a Moisturizer acronym: MOVHYDA overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-12 date: 2025-01 date: 2024-02-28 date: 2024-02-28 name: Biocodex class: INDUSTRY ... |
<|newrecord|> nctId: NCT06282601 id: GUIGOU - Defaye 2023 briefTitle: STUDY OF THE EFFECT OF RHYTHMIC AND NON-RHYTHMIC MUSICAL PRIMING ON THE SYNTAX CAPACITY OF PRESBYACOUSTIC OLDER ADULTS acronym: AMORCAGE MUSIC overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-03 date: 2024-03 date: 2024-02-28 date: 2024-02-... |
However, the specific effect of music on language skills has not yet been studied in hearing-impaired older adults. |
In this context, it was decided to study the effect of musical priming on the syntactic abilities of adults aged 70 or older with presbyacusis. |
This study is based on the hypothesis that music priming with regular music optimizes the syntax language skills of people with presbyacusis, as has already been proven in adults and normal-hearing children. conditions: Presbyacousie studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP pr... |
<|newrecord|> nctId: NCT06282588 id: CTO21042GZA briefTitle: Treatment of High-Risk Prostate Cancer Guided by Novel Diagnostic Radio- and Molecular Tracers acronym: THUNDER overallStatus: RECRUITING date: 2023-12-13 date: 2030-07-31 date: 2030-12-31 date: 2024-02-28 date: 2024-02-28 name: Cancer Research Antwerp class:... |
The hypothesis for the study is that treatment intensification based on a positive PSMA PET/ CT scan or Decipher high score (\> 0.6) improves time to new metastases detected on PSMA PET/ CT in high-risk PCa. In patients who are PSMA PET/ CT negative with a low/ intermediate Decipher score (≤ 0.6), it is hypothesized th... |
The study will be conducted at multiple centers across Europe. Participation in the study will comprise a screening period, where the screening assessments must be completed before subjects are enrolled and randomized (only for Phase 3 subjects). Eligible, consenting subjects will then undergo treatment according to th... |
<|newrecord|> nctId: NCT06282575 id: JZP598-302 id: 2023-508219-21-00 type: OTHER domain: CTIS briefTitle: Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer overallStatus: RECRUITING date: 2024-04-30 date: 2028-07-01 date: 2... |
<|newrecord|> nctId: NCT06282562 id: NL84223.018.23 briefTitle: FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor Patients acronym: FeelFit overallStatus: RECRUITING date: 2024-03 date: 2026-08-15 date: 2026-08-15 date: 2024-02-28 date: 2024-03-06 name: Amsterdam UMC, lo... |
<|newrecord|> nctId: NCT06282549 id: YMC046 briefTitle: Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients With Essential Hypertension overallStatus: RECRUITING date: 2022-06-08 date: 2027-03-31 date: 2027-03-31 date: 2024-02-28 date: 2024-02-28 name: Yuhan Corporation class: INDUSTRY briefSum... |
<|newrecord|> nctId: NCT06282536 id: LungMate-018 briefTitle: Neoadjuvant Therapy With Iruplinalkib for Potentially Resectable ALK Positive NSCLC: A Single Arm, Exploratory Trial overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-06 date: 2029-12 date: 2024-02-28 date: 2024-02-28 name: Shanghai Pulmonary Hospit... |
<|newrecord|> nctId: NCT06282523 id: 2023-1773 id: A171600 type: OTHER domain: UW- Madison id: EDUC/COUNSELING PSYCH type: OTHER domain: UW- Madison id: Protocol Version 12/27/23 type: OTHER domain: UW- Madison briefTitle: Healthy Minds Comparison Study overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-06 date... |
Participants will complete a four-week well-being program and complete surveys via an app on their phone. Participants can expect to participate in the study for four months. conditions: Depression conditions: Anxiety conditions: Depression/Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventio... |
<|newrecord|> nctId: NCT06282510 id: 23053003 briefTitle: Nasal Antisepsis for C. Auris Prevention overallStatus: RECRUITING date: 2024-01-29 date: 2026-12 date: 2028-12 date: 2024-02-28 date: 2024-02-28 name: Mary K Hayden class: OTHER name: Rush University Medical Center name: RML Specialty Hospital briefSummary: Thi... |
<|newrecord|> nctId: NCT06282497 id: ZSCPH-003 briefTitle: Xerostomia-optimised IMRT Versus Standard IMRT in NPC overallStatus: RECRUITING date: 2023-10-23 date: 2026-10-23 date: 2029-10-23 date: 2024-02-28 date: 2024-02-28 name: Zhongshan People's Hospital, Guangdong, China class: OTHER briefSummary: This is a multi-c... |
<|newrecord|> nctId: NCT06282484 id: KY20232348-C-1 briefTitle: A Study on the Relationship Between Gastric Xanthoma and Gastric Cancer and Precancerous Lesions overallStatus: COMPLETED date: 2022-09-01 date: 2023-06-01 date: 2023-09-29 date: 2024-02-28 date: 2024-02-28 name: Xijing Hospital of Digestive Diseases class... |
<|newrecord|> nctId: NCT06282471 id: MCC-23-20794 id: HM20028614 type: OTHER domain: Virginia Commonwealth University briefTitle: EW and Self-Guided PST in Cancer Survivors and Caregivers overallStatus: RECRUITING date: 2024-02-21 date: 2026-03-31 date: 2026-03-31 date: 2024-02-28 date: 2024-02-29 name: Virginia Common... |
<|newrecord|> nctId: NCT06282458 id: V2000101 briefTitle: Dose-Finding Study Evaluating Effect on Body Composition of Enobosarm in Patients Taking a GLP-1 for Chronic Weight Mgmt overallStatus: NOT_YET_RECRUITING date: 2024-04-29 date: 2024-12-20 date: 2025-04-30 date: 2024-02-28 date: 2024-04-24 name: Veru Inc. class:... |
The primary efficacy endpoint of the study will be the change from baseline in total lean mass at 4 months (112 days). Subjects will continue enobosarm (or matching placebo) monotherapy treatment from Day 112 to Day 196 to assess the effect of enobosarm on total lean mass, total muscle mass, maintenance of weight loss,... |
<|newrecord|> nctId: NCT06282445 id: K2024035 briefTitle: Efficacy and Safety of Chemotherapy With XELOX (Oxaliplatin + Capecitabine) and Bevacizumab in Combination With Adebrelimab in First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer overallStatus: RECRUITING date:... |
<|newrecord|> nctId: NCT06282432 id: RP-L201-0121-LTFU briefTitle: Long-Term Follow-Up (LTFU) for Gene Therapy of Leukocyte Adhesion Deficiency-I (LAD-I) overallStatus: ENROLLING_BY_INVITATION date: 2022-03-09 date: 2037-03 date: 2037-03 date: 2024-02-28 date: 2024-02-28 name: Rocket Pharmaceuticals Inc. class: INDUSTR... |
<|newrecord|> nctId: NCT06282419 id: B.30.2.ATA.0.01.00/542 briefTitle: The Effect of Visual and Audio Stimulus Offered to Father-to-be overallStatus: RECRUITING date: 2023-08-21 date: 2024-03-31 date: 2025-12-31 date: 2024-02-28 date: 2024-03-01 name: Ataturk University class: OTHER briefSummary: It was aimed to evalu... |
<|newrecord|> nctId: NCT06282406 id: N4532-R id: I0X1RX004532 type: OTHER_GRANT domain: U.S. Department of Veterans Affairs briefTitle: Pupil-Indexed Noninvasive Neuromodulation overallStatus: NOT_YET_RECRUITING date: 2024-06-03 date: 2028-04-03 date: 2028-08-05 date: 2024-02-28 date: 2024-02-28 name: VA Office of Rese... |
<|newrecord|> nctId: NCT06282393 id: Z-2023072 briefTitle: FibriCheck Data Registry acronym: FDR overallStatus: RECRUITING date: 2024-01-31 date: 2026-02 date: 2026-03 date: 2024-02-28 date: 2024-02-28 name: Qompium NV class: INDUSTRY briefSummary: The goal of this interventional clinical trial is to establish a compre... |
<|newrecord|> nctId: NCT06282380 id: FDA-AF study briefTitle: Fibricheck Detection cApabilities for Atrial Fibrillation acronym: FDA-AF overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-05 date: 2024-05 date: 2024-02-28 date: 2024-02-28 name: Qompium NV class: INDUSTRY briefSummary: Evaluation of accuracy of t... |
<|newrecord|> nctId: NCT06282367 id: JOSE AGURTO TELLO HOSPITAL briefTitle: Bowel Preparation for Colonoscopy With Oral Lactulose overallStatus: COMPLETED date: 2021-07-01 date: 2023-04-01 date: 2023-04-01 date: 2024-02-28 date: 2024-02-28 name: Josue Aliaga class: OTHER_GOV briefSummary: Background and Aims: The quali... |
Methods: Prospective non-blinded comparative study, developed in two tertiary centers from July 2021 to April 2023. Outpatients undergoing colonoscopy were randomly divided into 2 groups: Group 1 (111 patients): PEG and Group 2 (111 patients): Lactulose. The following clinical outcomes were assessed for each group: deg... |
<|newrecord|> nctId: NCT06282354 id: NP4035/2023 briefTitle: Telemedicine for Postoperative Follow-up After Oncological Surgeries overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-08-15 date: 2025-02-15 date: 2024-02-28 date: 2024-02-28 name: Instituto do Cancer do Estado de São Paulo class: OTHER briefSumm... |
<|newrecord|> nctId: NCT06282341 id: 23CH132 briefTitle: Fatigue and Recovery: a Comparison Between Trail and Marathon acronym: MARA-TRAIL overallStatus: RECRUITING date: 2023-12-28 date: 2025-08 date: 2025-09 date: 2024-02-28 date: 2024-02-28 name: Centre Hospitalier Universitaire de Saint Etienne class: OTHER briefSu... |
<|newrecord|> nctId: NCT06282328 id: CET 26-2024 briefTitle: HIV HOspital TEsting: Bringing the Hidden to Light in the Hospital Setting acronym: HIV-HOTE overallStatus: RECRUITING date: 2024-02-14 date: 2025-11-01 date: 2026-03-01 date: 2024-02-28 date: 2024-03-18 name: Castagna Antonella class: OTHER briefSummary: Thi... |
This is a cross-sectional, single-center study with additional procedures. Data collection will involve clinical and laboratory data from individuals with at least one HIV-IC and/or behavioral risk factor for HIV infection admitted to the San Raffaele Hospital in Milan for any reason. |
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