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Prehabilitation (Prehab) encompasses a series of interventions that are intended to help patients improve their physical state and psychological well-being pre-intervention to reduce the days of hospitalization and the number of post-operative complications. Patients who participate in Prehab require less postoperative... |
<|newrecord|> nctId: NCT06363630 id: CA073-1000 briefTitle: A Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibitor (Itraconazole) and Inducer (Rifampin) on the Drug Levels of Golcadomide (BMS-986369) in Healthy Participants overallStatus: NOT_YET_RECRUITING date: 2024-04-16 date: 2024-08-19 date: 2024-08-... |
<|newrecord|> nctId: NCT06363617 id: CSAPG-58 briefTitle: Implementation of the Fatty Liver Index in Primary Care acronym: FLI-AP overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-04-12 date: 2024-04-15 name: Consorci Sanitari de l'Alt Penedès i Garraf class: OTHER briefSummary: Thi... |
<|newrecord|> nctId: NCT06363604 id: XHEC-C-2023-128-2 briefTitle: Evaluation of PWI Assisted by Marshall Ethanolization in Ablation of Persistent Atrial Fibrillation overallStatus: RECRUITING date: 2023-12-01 date: 2026-09 date: 2026-11 date: 2024-04-12 date: 2024-04-12 name: Xinhua Hospital, Shanghai Jiao Tong Univer... |
Group 0 (Control): VOMEI + PVI + linear ablation of mitral isthmus. Group 1 (Experimental): VOMEI + PVI + linear ablation of mitral isthmus + PWI primaryPurpose: TREATMENT masking: SINGLE maskingDescription: This study used a single-blind design for the subjects. A statistician created a random sequence of numbers usin... |
<|newrecord|> nctId: NCT06363591 id: Wise vs wide briefTitle: Single- vs Two-staged Excisions of Thin Melanoma acronym: WvW overallStatus: NOT_YET_RECRUITING date: 2024-10-01 date: 2034-12-31 date: 2034-12-31 date: 2024-04-12 date: 2024-04-15 name: Vastra Gotaland Region class: OTHER_GOV name: Stockholm Region name: Re... |
1. Standard treatment with a WLE of the diagnostic excision scar with a lateral clinical surgical margin of 10 mm and a deep clinical surgical margin down to the muscular fascia as recommended by the Swedish national guidelines. |
or |
2. Experimental treatment with no WLE. primaryPurpose: TREATMENT masking: NONE count: 2486 type: ESTIMATED name: Wise vs wide measure: Recurrence rate at 5 years. measure: Recurrence rate at 10 years. measure: Postoperative complications measure: Scar length, width and quality measure: Scar length, width and quality me... |
<|newrecord|> nctId: NCT06363578 id: 36264PR604/3/24 briefTitle: Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2024-10-01 date: 2024-10-01 date: 2024-04-12 date: 2024-04-12 name: Tanta University class: OTHER briefS... |
<|newrecord|> nctId: NCT06363565 id: MN-2022-11 briefTitle: Effects of Supplementation of Compound Nutrients on Plasma Homocysteine in Chinese Adults overallStatus: RECRUITING date: 2023-06-01 date: 2025-12-31 date: 2025-12-31 date: 2024-04-12 date: 2024-04-12 name: Sun Yat-sen University class: OTHER briefSummary: The... |
<|newrecord|> nctId: NCT06363552 id: WETARI briefTitle: A Study of SC-0191 in Subjects With Metastatic Colorectal Cancer overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-04 date: 2025-12 date: 2024-04-12 date: 2024-04-12 name: Tianshu Liu class: OTHER briefSummary: The goal of this clinical trial is to evalua... |
<|newrecord|> nctId: NCT06363539 id: Adeel5 briefTitle: Silver Nitrate Versus Topical Steroid For Umbilical Granuloma overallStatus: COMPLETED date: 2022-09-20 date: 2023-03-20 date: 2023-05-01 date: 2024-04-12 date: 2024-04-12 name: Children Hospital and Institute of Child Health, Lahore class: OTHER briefSummary: Umb... |
<|newrecord|> nctId: NCT06363526 id: UMalagaDRIP briefTitle: Effectiveness of 5-week Digital Respiratory Practice in a Group of Children With Duchenne Muscular Dystrophy and Becker Muscular Dystrophy. acronym: DMDrespy2024 overallStatus: NOT_YET_RECRUITING date: 2024-05-05 date: 2024-10-30 date: 2024-11-30 date: 2024-0... |
<|newrecord|> nctId: NCT06363513 id: SUR2567-0150 briefTitle: The Efficacy of Aescin in Combination With MPFF in the Early Control of Bleeding From Acute Internal Hemorrhoids, A Randomized Controlled Trial overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-05 date: 2024-05 date: 2024-04-12 date: 2024-04-12 name... |
Upon comprehensive history-taking and examinations, including digital rectal and proctoscope assessments, a definitive diagnosis is established, leading to the treatment phase. Although outpatient procedures demonstrate efficacy, patients may persist with pain and discomfort. Medical intervention assumes significance f... |
Aescin, a saponin mixture found in Aesculus hippocastanum (horse chestnut). The primary active component, β-aescin, contributes to the plant's medicinal attributes. Experimental investigations in animal models underscore its anti-edematous, anti-inflammatory, and venotonic properties, attributed to molecular mechanisms... |
<|newrecord|> nctId: NCT06363500 id: ChantalIRCB briefTitle: Characterization of HIV-1 Reservoirs in HIV-1 Non-B Infected Adolescents on ART in Cameroon acronym: AVIR overallStatus: COMPLETED date: 2021-11-01 date: 2023-10-30 date: 2023-11-30 date: 2024-04-12 date: 2024-04-12 name: Chantal Biya International Reference ... |
Objectives: We plan to conduct a cross sectional study with the aim to characterize HIV reservoirs and their variability according to virological and immunological profiles of non-B HIV-1 vertically infected adolescents receiving antiretroviral therapy. Specifically, we shall (1) evaluate the size of HIV reservoir; (2)... |
Methods: We plan to conduct an observational and comparative study involving 90 HIV-1 non-B infected adolescents aged 10-19 years vertically infected, have been on ART for at least 12 months selected from a cohort of the ongoing EDCTP-READY study; intravenous blood will be collected for CD4/CD8 count, plasmatic viral l... |
Overall impact: Our findings will help in advancing knowledge on HIV reservoir, in terms of size and genetic variability in adolescents living with HIV (ADLHIV). Such evidence will also help in understanding the effects of ART timing and duration on the size of reservoirs among ADLHIV, a unique population from whom fin... |
<|newrecord|> nctId: NCT06363487 id: R87970/RE001 briefTitle: Semaglutide and Cognition in Healthy Volunteers acronym: OxSENSE overallStatus: NOT_YET_RECRUITING date: 2024-04-08 date: 2024-04-08 date: 2024-06-08 date: 2024-04-12 date: 2024-04-12 name: University of Oxford class: OTHER name: NIHR Oxford Health Biomedica... |
<|newrecord|> nctId: NCT06363474 id: UHS 5532 briefTitle: Cisternostomy Vs Decompressive Craniectomy for Severe Traumatic Brain Injury overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-05-01 date: 2024-04-12 date: 2024-04-12 name: University of Health Sciences Lahore class: OTHER briefSumma... |
This prospective study will be conducted at the Department of Neurosurgery, Punjab Institute of Neurosciences, Lahore. Patients meeting inclusion criteria will be randomized into Group A (DC) and Group B (Cisternostomy) following brain CT scans. Clinical evaluation will include regular follow-ups for 6 months post-surg... |
It is hypothesized that Cisternostomy, as an adjunct to traditional TBI management, will effectively reduce ICP, resulting in improved GOS and reduced complications postoperatively, including decreased duration of mechanical ventilation and ICU stay, with sustained improvement observed at 6 months conditions: Severe Tr... |
<|newrecord|> nctId: NCT06363461 id: 239-13851-202 briefTitle: Study of TDM-180935 in Atopic Dermatitis Patients overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-09-30 date: 2024-10-31 date: 2024-04-12 date: 2024-04-12 name: Technoderma Medicines Inc. class: INDUSTRY name: Therapeutics, Inc. briefSummary: ... |
<|newrecord|> nctId: NCT06363448 id: Soh-Med-24-3-04PD briefTitle: Yamani Technique Versus Proline Mesh for Intraocular Lens Scleral Fixation in Aphakia overallStatus: RECRUITING date: 2024-01-01 date: 2024-06-30 date: 2024-07-30 date: 2024-04-12 date: 2024-04-12 name: Sohag University class: OTHER briefSummary: The st... |
<|newrecord|> nctId: NCT06363435 id: #2022-01302-02-PSMA briefTitle: AI-based Measurements of Tumour Burden in PSMA PET-CT overallStatus: RECRUITING date: 2024-03-29 date: 2031-03 date: 2033-03 date: 2024-04-12 date: 2024-04-12 name: Elin Tragardh class: OTHER name: Lund University briefSummary: The primary aim of the ... |
<|newrecord|> nctId: NCT06363422 id: JY2024-012 briefTitle: The Value of Epicanthoplasty on the Modification of Upper-eyelid Appearance overallStatus: COMPLETED date: 2024-01-01 date: 2024-03-15 date: 2024-04-01 date: 2024-04-12 date: 2024-04-12 name: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong Un... |
<|newrecord|> nctId: NCT06363409 id: 2023-1353 briefTitle: The Acute and Accumulative Effects of Snack Foods on Exercise Recovery overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-06-01 date: 2027-01-01 date: 2024-04-12 date: 2024-04-12 name: San Diego State University class: OTHER briefSummary: The purpose... |
<|newrecord|> nctId: NCT06363396 id: K 2023-7081 briefTitle: Fatigue and Cognitive Dysfunction After Allogeneic Stemcell Transplantation, Prospective PET Study overallStatus: RECRUITING date: 2024-02-22 date: 2026-02-22 date: 2027-02-22 date: 2024-04-12 date: 2024-04-12 name: Karolinska Institutet class: OTHER name: Ka... |
* by using mass spectrometry-based proteomics approaches |
* Olink technology |
PET examinations will be performed on both fatigued and non-fatigued. We will utilize the second generation TSPO radioligand \[ 11C\]PBR28 as well as the SV2A radioligand \[ 11C\]UCB-J, both showing high signal-to-noise ratio and adequate test-retest properties. conditions: Fatigue conditions: Cognitive Dysfunction stu... |
<|newrecord|> nctId: NCT06363383 id: MB-001-101 briefTitle: A Phase 1 Study to Evaluate the Safety of an Oral Biologic in Healthy Participants overallStatus: RECRUITING date: 2024-05-09 date: 2025-05 date: 2025-05 date: 2024-04-12 date: 2024-04-18 name: Mage Biologics class: INDUSTRY name: Alimentiv Inc. briefSummary: ... |
Is the drug safe when administered orally at increasing doses? Researchers will compare the drug with placebo to see if there are more side effects in those receiving the drug. |
Participants will receive a single or five daily doses of the drug or placebo and will be asked to stay in the clinic for five days following the last dose. conditions: Ulcerative Colitis studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: two-stage,... |
<|newrecord|> nctId: NCT06363370 id: KXZY-GB05-201 briefTitle: Human Interferon α1b Inhalation Solution Against Respiratory Syncytial Virus in Children With Lower Respiratory Tract Infections overallStatus: RECRUITING date: 2024-03-27 date: 2026-06-30 date: 2026-06-30 date: 2024-04-12 date: 2024-04-12 name: Kexing Biop... |
<|newrecord|> nctId: NCT06363357 id: 24B-007-0000 briefTitle: The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Duchenne Muscular Dystrophy overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2025-12-31 date: 2025-12-31 date: 2024-04-12 date:... |
The main questions it aims to answer are: |
* What is the impact of the muscle-mimicking, fabric-type shoulder orthosis on upper limb functional movements in patients with Duchenne muscular dystrophy? |
* Are there observable differences in upper limb function when the shoulder orthosis is worn versus when it is not? |
Participants will: |
* Receive education on how to wear and use the shoulder orthosis. |
* Undergo evaluations, including assessment of upper limb performance, shoulder muscle strength testing, active range of motion measurements, assessment of functional workspace, goal attainment scale evaluation, surface electromyography, physiological measurements such as blood pressure and heart rate, fatigue assessme... |
Researchers will compare Duchenne muscular dystrophy patients before and while wearing and operating the shoulder orthosis to see if there are any significant effects on variables such as upper limb function, range of motion, functional workspace, goal attainment scale, and surface electromyography. conditions: Muscula... |
<|newrecord|> nctId: NCT06363344 id: APHP231022 id: IDRCB: 2023-A00660-45 type: REGISTRY domain: IDRCB ANSM briefTitle: Follow-up in Pediatric Intensive Care Unit acronym: APRELAREA overallStatus: RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2025-09-01 date: 2024-04-12 date: 2024-04-15 name: Assistance Publique -... |
Objectives Main objective: To assess the feasibility of implementing systematic and comprehensive management of pediatric patients who have been admitted to the PICU. |
Intermediate objectives are to study: |
* The needs of the children and their families which should be met by this management |
* The acceptability of this organizational innovation for all the actors involved |
* The cooperation between actors of the hospital and city health system + social professionals involved |
* The costs of implementation and the budgetary impact of such a system |
Methods Needs assessment: questionnaires and interviews with patients and their families (parents and possibly siblings if involved) to collect the medico-psycho-social impact of the PICU stay at the time of discharge and 3 months later. |
Study of acceptability: quantitative survey of health professionals involved in the care of these children and expected care modalities. This includes pediatric intensivists, professionals from the children's usual care services (if applicable), attending physician. |
Study of cooperation: analysis of needs and of the network usually solicited for the children benefiting from this care: who is identified, who remains to be identified, obstacles. Quantitative analysis of consultation reports and survey of professionals. |
Budgetary impact analysis: study of the cost of setting up consultations for the health care system, and study of its financial and health consequences for the main needs identified, on the basis of data from the literature and expert opinions |
Perspectives Compare the benefit of this systematic, multi professional and comprehensive management of pediatric patients after PICU discharge versus standard of care conditions: Intensive Care Psychosis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: SUPPORTIVE_CARE... |
<|newrecord|> nctId: NCT06363331 id: 2020I054 briefTitle: Efficacy of the Social Cognition Rehabilitation Program E-motional Training in the Treatment of Patients With Substance-related Disorders overallStatus: COMPLETED date: 2022-03-01 date: 2022-12-01 date: 2023-12-30 date: 2024-04-12 date: 2024-04-12 name: Fundacin... |
Since addictive behaviors have been consistently associated with the presence of alterations in cognitive and executive functions, it is necessary to be able to detect, evaluate and have specific therapies for these dysfunctions and investigate, among other issues, the role they play in the onset and course evolutionar... |
To characterize the presence of alterations in the domains that make up social cognition (SC) in patients with SUD and test in our healthcare units the ET® program already tested both experimentally and at beta level. It is an online self-training program for CS rehabilitation that includes modules for emotion recognit... |
To replicate the RCT carried out in schizophrenia in patients with SUD with difficulties in RE or ToM, in addition to searching for a biomarker or a pattern of them that predict the patient profile that will benefit from the training, using advanced LC-ESI proteomics techniques. MS/MS in saliva since previous studies i... |
From the perspective of the State Plan for Scientific and Technical Research and Innovation, this project combines CLINICAL AND TRANSLATIONAL RESEARCH, based on the evidence of scientific and technological knowledge, and the use of ENABLING TECHNOLOGIES of e-health in the area of Health Services. Health for people with... |
<|newrecord|> nctId: NCT06363318 id: 0003 briefTitle: Comparison of Open and Laparoscopic Appendectomy in Pediatric Population acronym: Appendicitis overallStatus: COMPLETED date: 2019-07-01 date: 2019-11-30 date: 2019-11-30 date: 2024-04-12 date: 2024-04-15 name: King Edward Medical University class: OTHER briefSummar... |
Objectives: To compare the outcome of open and laparoscopic appendectomy in children presenting with appendicitis in terms of operative time, postoperative pain, wound infection and hospital stay. conditions: Appendicitis Acute studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL inte... |
<|newrecord|> nctId: NCT06363305 id: 2402-1139 briefTitle: Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-12-01 date: 2025-12-31 date: 2024-04-12 date: 2024-04-18 name: Skidmore College class: OTHER name: American Heart Association... |
<|newrecord|> nctId: NCT06363292 id: SOPH231-1221/I briefTitle: Study to Evaluate the Safety and Tolerability of PRO-231 Ophthalmic Solution Versus VIGAMOXI® on the Ocular Surface of Healthy Subjects. overallStatus: RECRUITING date: 2024-01-30 date: 2024-05-30 date: 2024-05-30 date: 2024-04-12 date: 2024-04-15 name: La... |
<|newrecord|> nctId: NCT06363279 id: 2024/24JAN/044 briefTitle: Validation of the French ATI Scale and Predisposition to Use Technological Tools in Rehabilitation. overallStatus: RECRUITING date: 2024-04-04 date: 2024-09 date: 2024-10 date: 2024-04-12 date: 2024-04-12 name: Cliniques universitaires Saint-Luc- Universit... |
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