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The second objective is to determine the extent to which the general population is prepared to use technological tools as part of their rehabilitation. The aim is to gain a better understanding of the profile of people who could potentially benefit from tele-rehabilitation. Accessibility to the technologies, their expe... |
<|newrecord|> nctId: NCT06363266 id: 190211_1 briefTitle: A SMART Design to Optimize the Delivery of TEMPO for Men With Prostate Cancer and Their Caregivers overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2026-08-31 date: 2028-08-31 date: 2024-04-12 date: 2024-04-12 name: St. Mary's Research Center, Canada cla... |
<|newrecord|> nctId: NCT06363253 id: CIRB Ref: 2023/2073 briefTitle: Pilot Study of the Human Metagenome in Metabolic Diseases overallStatus: RECRUITING date: 2023-08-14 date: 2026-12-31 date: 2027-12-31 date: 2024-04-12 date: 2024-04-12 name: Sengkang General Hospital class: OTHER name: Singapore General Hospital name... |
Recruited participants will have their fecal, salivary, urine, serum, and in certain instances, mucosal samples taken, for metagenomic sequencing and metabolite testing. |
We hope to uncover various differences and signatures in the metagenome and metabolome in various diseased states, with potential future therapeutic applications in personalised medicine. conditions: Obesity conditions: Sarcopenia conditions: Sarcopenic Obesity conditions: Chronic Inflammation conditions: Metabolic Syn... |
<|newrecord|> nctId: NCT06363240 id: CBBLCIP001 briefTitle: Evaluation of Broadband Light Treatment for Solar Lentigines overallStatus: RECRUITING date: 2024-03-12 date: 2024-12-20 date: 2025-01-30 date: 2024-04-12 date: 2024-04-12 name: Sciton class: INDUSTRY briefSummary: Broadband light treatment for Solar Lentigine... |
<|newrecord|> nctId: NCT06363227 id: ANEST-0003 briefTitle: Postoperative Pain After Implementation of Standardized Pain Therapy Management in Orthopaedic Patients acronym: PAIN overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-02 date: 2025-04 date: 2024-04-12 date: 2024-04-16 name: Schulthess Klinik class: O... |
<|newrecord|> nctId: NCT06363214 id: ANEST-0002 briefTitle: Impact of Patient Blood Management (PBM) at the Schulthess Clinic acronym: PBM overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-02 date: 2025-04 date: 2024-04-12 date: 2024-04-16 name: Schulthess Klinik class: OTHER briefSummary: Aim of this study is... |
<|newrecord|> nctId: NCT06363201 id: CAT2024/PED01 briefTitle: Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours overallStatus: NOT_YET_RECRUITING date: 2024-04-28 date: 2024-12-15 date: 2025-12-15 date: 2024-04-12 date: 2024-04-12 name: Catalysis ... |
<|newrecord|> nctId: NCT06363188 id: effect of ESWT on fractures briefTitle: The Impact of ESWT on Healing of Fractured Mandible overallStatus: RECRUITING date: 2024-02-01 date: 2024-08-01 date: 2025-08-30 date: 2024-04-12 date: 2024-04-12 name: Cairo University class: OTHER briefSummary: studying if using extracorpore... |
<|newrecord|> nctId: NCT06363175 id: 8737 id: 343073 type: OTHER domain: Integrated Research Application system (IRAS) briefTitle: PREMs In Vascular SurgERy Enhancement Study acronym: PREMIERE overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-08-01 date: 2026-06-01 date: 2024-04-12 date: 2024-04-15 name: Ca... |
Patient Reported Experience Measures (PREMs) ask patients about their healthcare service experience. It gives them a voice to share their views. PREMs allow healthcare providers (HCPs) to see where care is good, and where they could improve. Vascular surgery is a surgical speciality looking after people's blood vessels... |
There is no PREM available for vascular patients. The research team want to create a PREM for this patient group. |
WHY IT IS IMPORTANT: |
A PREM allows HCPs to record and understand patients' experiences of their treatment. It gives patients a way to provide feedback on their healthcare experience. PREMs can help HCPs make changes to patients' care, identifying areas of good practice and areas for improvement. The Welsh Government is keen to support the ... |
AIMS: |
To develop a PREM specific to vascular surgery patients. |
RESEARCH PLAN: |
The research team will summarise the literature about PREMs in surgery. The research team will then run focus groups and interviews with patients and staff to create a 'draft' PREM for vascular patients in Wales. The 'draft' PREM will be translated into Welsh. |
In the second phase, a larger number of vascular patients (100-300 depending on how long the 'draft' PREM is) from hospitals across Wales will complete the questionnaire. Statistical tests will look at the results to see if the questionnaire works well to capture patients' experiences. Based on these results, small cha... |
PATIENT AND PUBLIC INVOLVEMENT: |
The patients' experience team at CAVUHB has reviewed our patients' materials. Our research team includes PPI co-applicants (DC and AH). DC a double amputee who has had many vascular operations. DC has experience raising awareness about vascular disease through public forums like the Limbless Association Charity and BBC... |
<|newrecord|> nctId: NCT06363162 id: LRR202404 briefTitle: Evaluate the Effectiveness and Safety of Raman IVD Analyzer in the Molecular Diagnosis of Gliomas During Surgery overallStatus: RECRUITING date: 2022-12-01 date: 2025-06-30 date: 2025-12-31 date: 2024-04-12 date: 2024-04-12 name: Beijing Tiantan Hospital class:... |
<|newrecord|> nctId: NCT06363149 id: 2024-11-DM-136 briefTitle: Disseminated Intravascular Coagulation (DIC) Score and Organ Dysfunction in Septic Shock Patients overallStatus: RECRUITING date: 2024-04-12 date: 2025-09 date: 2025-09 date: 2024-04-12 date: 2024-04-16 name: Sanjay Gandhi Postgraduate Institute of Medical... |
Both DIC and septic shock individually are associated with very high mortality and morbidity and coexistence of both increase risk manifold. Organ dysfunction is a complication of both septic shock and DIC individually and in presence of coexistence risk further multiply. DIC scoring of every patient at risk as in pati... |
Understanding effects of DIC on organ dysfunction in septic shock patients can help to prognosticate and guide towards early intervention. Also, there is paucity of literature on effect of DIC score changes on organ dysfunction in patients with septic shock. conditions: Septic Shock conditions: Disseminated Intravascul... |
<|newrecord|> nctId: NCT06363136 id: 14.06.2023-111176 briefTitle: Foot Posture, Strength, Performance, and Postural Control in Isolated Gastrocnemius Tightness overallStatus: RECRUITING date: 2024-02-01 date: 2024-05-30 date: 2024-06-30 date: 2024-04-12 date: 2024-04-12 name: Bezmialem Vakif University class: OTHER br... |
In the literature, there is no study evaluating foot posture, muscle strength, functional performance, and postural control in children with isolated gastrocnemius muscle tightness. It was planned to evaluate postural control using computerized dynamic posturography (Biodex Balance System), lower extremity muscle stren... |
<|newrecord|> nctId: NCT06363123 id: BFHHZML20240009 briefTitle: Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis overallStatus: RECRUITING date: 2024-03-29 date: 2024-10 date: 2025-04 date: 2024-04-12 date: 2024-04-15 name: Beijing Friendship Hospital class: OTHER briefSummary: The aim of this observational stud... |
<|newrecord|> nctId: NCT06363110 id: 22724 briefTitle: An Observational Study to Learn More About Vericiguat Treatment Patterns and Its Safety in People With Chronic Heart Failure With Reduced Ejection Fraction in Routine Medical Care in the United States acronym: HOVER overallStatus: ACTIVE_NOT_RECRUITING date: 2024-0... |
In observational studies, only observations are made, without participants receiving any advice or any changes to healthcare. |
Chronic HFrEF is a long-term condition in which the heart becomes weak and cannot pump enough blood to the rest of the body with each heartbeat. This leads to a reduced supply of oxygen, which the body requires to function properly. |
The study treatment, vericiguat, works by increasing the activity of an enzyme called soluble guanylate cyclase (sGC), which relaxes the blood vessels and allows more blood to flow. As a result, the heart can pump better. |
It is already approved for doctors to prescribe to people with chronic HFrEF in the United States (US) who are stabilized after a recent "decompensation event". The treatment with vericiguat starts at a low dose, which should be increased gradually to the target dose based on how a patient tolerates the treatment. |
The participants in this study are already receiving treatment with vericiguat as part of their regular care from their doctors. |
The main purpose of the study is to learn more about the dosage pattern of vericiguat in people with chronic HFrEF in the US. To do this, researchers will collect the following information for 3 months after participants' first dose of vericiguat: |
* starting dose of vericiguat |
* daily changes in dosage pattern |
* time taken to reach the target dose |
* number and percentage of participants: |
* with specific changes in dosage pattern |
* reaching the target dose of vericiguat |
They will also collect information on how often low blood pressure or fainting occurs, which are well known events in people with chronic HFrEF. |
The data will come from the participants' information stored in a database called the HealthVerity HF dataset. Data collected will be from people with chronic HFrEF who started taking vericiguat between January 2021 and April 2023. |
Researchers will only look at the health records of participants in the US. |
Researchers will track participants' data and will collect information for a maximum of 6 months before and 3 months after their first dose of vericiguat. |
In this study, only available data from routine care are collected. No visits or tests are required as part of this study. conditions: Chronic Heart Failure With Reduced Ejection Fraction studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 1400 type: ESTIMATED name: Vericiguat (Ver... |
<|newrecord|> nctId: NCT06363097 id: ΔΔ5032 briefTitle: Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease overallStatus: RECRUITING date: 2023-09-04 date: 2024-12 date: 2025-06 date: 2024-04-12 date: 2024-04-12 name: Aristotle University Of Thessaloniki clas... |
<|newrecord|> nctId: NCT06363084 id: IST-Nim-PC-6 briefTitle: A Retrospective Study for Nimotuzumab Plus Postoperative Adjuvant Chemotherapy for Resectable Pancreatic Cancer overallStatus: COMPLETED date: 2016-05-01 date: 2022-07-31 date: 2023-06-30 date: 2024-04-12 date: 2024-04-12 name: Ruijin Hospital class: OTHER b... |
<|newrecord|> nctId: NCT06363071 id: 202000495A3 briefTitle: APA and PAS Training for Gait Initiation in Parkinson's Disease overallStatus: RECRUITING date: 2022-06-13 date: 2025-03-31 date: 2025-05-31 date: 2024-04-12 date: 2024-04-12 name: Chang Gung University class: OTHER briefSummary: Our research focused on under... |
<|newrecord|> nctId: NCT06363058 id: 201902166B0 briefTitle: Electrical Stimulation Cycling Training Effects on SCA overallStatus: RECRUITING date: 2022-04-08 date: 2025-07-31 date: 2025-07-31 date: 2024-04-12 date: 2024-04-17 name: Chang Gung University class: OTHER briefSummary: To focuses on the challenges faced by ... |
<|newrecord|> nctId: NCT06363045 id: NIDEK-TONOREF-UK-0001 briefTitle: Comparative Study of the NIDEK TONOREF III With Predicate Devices overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-11 date: 2024-11 date: 2024-04-12 date: 2024-04-17 name: Nidek Co. LTD. class: INDUSTRY briefSummary: The primary objective ... |
<|newrecord|> nctId: NCT06363032 id: 202110104RINB briefTitle: Elastography in Predicting Renal Outcome overallStatus: RECRUITING date: 2021-12-27 date: 2024-12-31 date: 2025-12-31 date: 2024-04-12 date: 2024-04-12 name: National Taiwan University Hospital class: OTHER briefSummary: There are two types of elastography:... |
Transthoracic shear-wave ultrasound is also used for the prediction of lung malignancy. |
In progressive renal disease, renal function decline correlates with the extent of interstitial fibrosis, irrespective of the original pathology. Experience and research in using shear-wave elastography to study the stiffness of renal parenchyma and renal fibrosis are scanty. The investigators will conduct a prospectiv... |
By assuming a power of 0.8, a two-side p value of 0.05, a ratio of 0.2 (sample sizes in negative/positive groups) to detect the difference between area under ROC curve and null hypothesis value (0.8 and 0.7), a target sample of 273 (with a 5% cushion, 260\~290) patients is required. conditions: Kidney Disease studyType... |
<|newrecord|> nctId: NCT06363019 id: 2023/00158 briefTitle: Supporting At-Risk Mothers Across Perinatal Period acronym: SMART overallStatus: RECRUITING date: 2024-02-26 date: 2025-02-26 date: 2026-07-06 date: 2024-04-12 date: 2024-04-12 name: National University of Singapore class: OTHER name: Ministry of Health, Singa... |
The goal of this interventional study is to test the effectiveness of a mobile-app health based intervention, SMART, mothers in the perinatal period. |
The main questions this study aims to answer are: |
1. What is the effect of a mobile-based health intervention, SMART, on maternal outcomes? |
2. What is the effect of a mobile-based health intervention, SMART, on infant outcomes? |
3. What is the cost-effectiveness of using SMART as compared to standard routine care? |
Researchers will compare results with a control group that will undergo standard routine care. conditions: Perinatal Depression conditions: Parents conditions: Anxiety conditions: Self Efficacy conditions: Stress conditions: Infant Development studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionMode... |
<|newrecord|> nctId: NCT06363006 id: K23C3280 briefTitle: Combination of Cardonizumab Injection and TKI Second Line Therapy for Advanced Hepatocellular Cancer overallStatus: RECRUITING date: 2024-03-11 date: 2026-01-01 date: 2027-01-01 date: 2024-04-12 date: 2024-04-12 name: Peking Union Medical College Hospital class:... |
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