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Purpose: This study aims to evaluate the effect of antigravity treadmill training on pain, gait characteristics, and function in patients with knee osteoarthritis. conditions: Knee Osteoarthritis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The st... |
<|newrecord|> nctId: NCT06347679 id: WCHSIRB-CT-2024-160 briefTitle: Effects of Aromatherapy on Anxiety and Pain During Dental Treatments in Adults: a Randomized Controlled Clinical Trial overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2026-04-01 date: 2024-04-04 date: 2024-04-04 name: Sichuan... |
<|newrecord|> nctId: NCT06347666 id: 23082905 briefTitle: Coaching in Early Development Project overallStatus: RECRUITING date: 2024-01-12 date: 2025-02 date: 2025-07 date: 2024-04-04 date: 2024-04-04 name: Rush University Medical Center class: OTHER briefSummary: Among young children, homelessness is an independent pr... |
<|newrecord|> nctId: NCT06347653 id: 2023KT127 briefTitle: Linperlisib-based Treatment Regimen in Newly Diagnosed Nodal T-follicular Helper Cell Lymphoma (nTFHL) overallStatus: RECRUITING date: 2023-11-28 date: 2027-01-31 date: 2030-01-31 date: 2024-04-04 date: 2024-04-04 name: Peking University class: OTHER briefSumma... |
<|newrecord|> nctId: NCT06347640 id: KingAbdullahUH2 briefTitle: Outcome of Pulp Revascularization of Necrotic Mature Permanent Teeth Using Platelet-rich Fibrin overallStatus: RECRUITING date: 2023-04-01 date: 2025-12-01 date: 2027-12-01 date: 2024-04-04 date: 2024-04-04 name: King Abdullah University Hospital class: O... |
However, it has been recently suggested for treating fully formed mature necrotic permanent teeth with closed apices since the conventional root canal treatment yielded many drawbacks. |
A number of studies have evaluated the regeneration outcomes of using blood clot as a scaffold. However, there are limited studies in the literature on using other scaffolds such as platelet-rich fibrin (PRF). |
This clinical study will evaluate clinically and radiographically the effectiveness of PRF versus induced bleeding in treating mature necrotic teeth. Fifty patients with necrotic mature teeth with periapical lesions will be invited to participate in this study. Teeth will be treated using calcium hydroxide as intracana... |
<|newrecord|> nctId: NCT06347627 id: UW23139 briefTitle: Communicating Human Papillomavirus Vaccine With Japanese Parents and Caregivers With Daughters Aged 12-18 overallStatus: ENROLLING_BY_INVITATION date: 2023-12-22 date: 2024-12 date: 2024-12 date: 2024-04-04 date: 2024-04-04 name: The University of Hong Kong class... |
<|newrecord|> nctId: NCT06347614 id: 2021-FXY-042 briefTitle: Modified Radical Prostatectomy for Prostate Cancer Patients With Enlarged Prostate and Severe Lower Urinary Tract Symptoms: a Single-center, Retrospective Study acronym: Two-step RP overallStatus: ACTIVE_NOT_RECRUITING date: 2021-09-01 date: 2024-12-01 date:... |
<|newrecord|> nctId: NCT06347601 id: 2024-03-011AC briefTitle: Survey on Sexual and Gender in the Healthcare in Taiwan overallStatus: RECRUITING date: 2024-03-13 date: 2025-02-01 date: 2025-02-20 date: 2024-04-04 date: 2024-04-29 name: Taipei Veterans General Hospital, Taiwan class: OTHER_GOV briefSummary: This study a... |
<|newrecord|> nctId: NCT06347588 id: OBI&ICI briefTitle: Risk of Reactivation of Occult Hepatitis B in Cancer Patients During Immunotherapy. overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-05 date: 2026-12 date: 2024-04-04 date: 2024-04-05 name: Fondazione IRCCS Policlinico San Matteo di Pavia class: OTHER b... |
<|newrecord|> nctId: NCT06347575 id: APHP230522 briefTitle: Safety and Tolerability of a Novel Implantable Neurostimulator for Ameliorate Erectile Function on Spinal Cord Injured Patients acronym: CAVERSTIM overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-11 date: 2025-11 date: 2024-04-04 date: 2024-04-04 nam... |
As the secondary objectives, despite the limited cohort size, this long-term study aims to obtain preliminary data on efficacy of cavernous nerve stimulation to improve erectile function for sexual intercourse, as well as to assess patient's satisfaction using: |
* Objective assessment of the erectile response upon CaverSTIM activation with the RigiScan device. |
* Subjective assessment of the erectile function with validated questionnaires: |
1. A 6-item self-report instrument assessing male erectile function (Erectile Function domain of the International Index of Erectile Function, IIEF-EF); |
2. A log-diary five item questionnaire completed after each sexual attempt (Sexual Encounter Profile, SEP); |
3. A self-reporting measure that scores erection hardness on a 4-point scale (Erection Hardness Score, EHS); |
4. The Global Assessment Question (GAQ). |
In addition, the study aims to refine the method of implantation (step-by-step delineation of all technical approaches for device implantation, including duration of surgical procedure, blood loss, methods to access the periprostatic region, tissue dissection, device placement and fixation) prior to planning for larger... |
<|newrecord|> nctId: NCT06347562 id: 934 briefTitle: Optical Genome Mapping for the Diagnosis of Neurodevelopmental Disorders overallStatus: RECRUITING date: 2022-06-15 date: 2025-06-14 date: 2025-06-14 date: 2024-04-04 date: 2024-04-04 name: IRCCS Eugenio Medea class: OTHER briefSummary: to evaluate the ability of the... |
<|newrecord|> nctId: NCT06347549 id: HE-SF2024/09 briefTitle: The Impact of Diaphragmatic Breathing Instructions and Inspiratory Pressures on Diaphragm Contraction in Healthy Adults overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2026-04-15 date: 2026-04-15 date: 2024-04-04 date: 2024-04-04 name: Hong Kong Met... |
This study aims (1) to investigate the relationship between sternocleidomastoid muscle recruitment and diaphragm thickness fraction during increasing inspiratory resistance in healthy adults; (2) to compare diaphragmatic and sternocleidomastoid muscle recruitment patterns with and without a standard diaphragmatic breat... |
Participants will be asked to breathe through a pressure threshold inspiratory loading device under different inspiratory resistances with and without a standard diaphragmatic breathing instruction. sternocleidomastoid muscle activity will be measured with surface electromyography, and diaphragm thickness will be asses... |
<|newrecord|> nctId: NCT06347536 id: IRAS331831 id: NIHR156698 type: OTHER_GRANT domain: NIHR HTA briefTitle: Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease acronym: RAPID overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2027-12-31 date: 2027-12-31 date: 2024-04-04 date: 2024-04-19 ... |
Severe exacerbations, where patients are hospitalised, are of particular concern to patients, carers and healthcare givers. The National Institute for Health and Care Excellence (NICE) recommends that hospital clinicians looking after patients with COPD should provide rescue packs (a course of prednisolone and antibiot... |
A multicentre randomised clinical trial of 1400 patients will be conducted in 30 acute NHS trusts. This will test the hypothesis that a self-supported rescue pack management plan consisting of rescue packs + written self-management plan + twice weekly telephone/text symptom alert assessments in the high-risk 90-day per... |
<|newrecord|> nctId: NCT06347523 id: FirstShantou briefTitle: VR-Based Preoperative Rehabilitation Program for Patients Undergoing Anterior Cruciate Ligament (ACL) Reconstruction overallStatus: RECRUITING date: 2024-04-02 date: 2024-10-01 date: 2024-12-31 date: 2024-04-04 date: 2024-04-04 name: First Affiliated Hospita... |
<|newrecord|> nctId: NCT06347510 id: E-25403353-050.99-174660 briefTitle: The Level of sST2 in Pediatric Heart Failure overallStatus: COMPLETED date: 2021-08-16 date: 2024-02-16 date: 2024-02-16 date: 2024-04-04 date: 2024-04-04 name: Eskisehir Osmangazi University class: OTHER briefSummary: Introduction: Suppression o... |
Method: The study included pediatric patients (0-18 years old) with congenital heart disease or cardiomyopathy who needed medical care as well as surgical or interventional treatment. Height, weight, gender, saturation, heart failure classification (Ross or New York heart Assosiation), medications taken, the electrocar... |
<|newrecord|> nctId: NCT06347497 id: 000001230988 briefTitle: Zonisamide Versus Topiramate in Migraine overallStatus: RECRUITING date: 2024-04-01 date: 2025-04-02 date: 2025-05-01 date: 2024-04-04 date: 2024-04-24 name: Kafrelsheikh University class: OTHER briefSummary: Investigators aim to compare the effect of zonisa... |
<|newrecord|> nctId: NCT06347484 id: IRB00411716 briefTitle: Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT) acronym: CONNECT overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-12 date: 2026-10 date: 2024-04-04 date: 2024-04-04 name: Johns Hopkin... |
<|newrecord|> nctId: NCT06347471 id: SBS-2023-477 briefTitle: The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapy acronym: SPARTAN overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-12 date: 2026-04 date: 2024-04-04 date: 2024-04-04 name: Infectious ... |
Before, during and after ACT treatment, the transmission potential of artemisinin resistant and wild type infections will be assessed by microscopy, molecular methods, parasite culture and mosquito feeding assays. Parasite clearance will be determined in the first days (d0-3) after treatment. |
The study population will consist of passively recruited patients with uncomplicated P. falciparum malaria who are microscopy positive for gametocytes. Participants will be treated with conventional therapies for uncomplicated malaria without randomization: artemether-lumefantrine (AL) or dihydroartemisinin-piperaquine... |
Gametocyte carriage and gametocyte commitment/production will be determined for resistant and wild type infections before, during and after treatment. In addition, venous blood will be collected at three timepoints to assess transmission to mosquitoes before (d0), during (d2) and after treatment (d7). The total duratio... |
<|newrecord|> nctId: NCT06347458 id: BG-CA-23-001 briefTitle: BG1805 Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia in Children overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-04 date: 2027-08 date: 2024-04-04 date: 2024-04-04 name: Guangzhou Bio-gene Technology Co., Ltd class: I... |
<|newrecord|> nctId: NCT06347445 id: GSM012024 briefTitle: Turkish Nationwide SurvEy of Glycemic and Other Metabolic Parameters of Patients With Diabetes Mellitus-2 (TEMD-2 Study) acronym: TEMD-2 overallStatus: COMPLETED date: 2022-10-01 date: 2023-01-30 date: 2023-01-30 date: 2024-04-04 date: 2024-04-04 name: Gulhane ... |
<|newrecord|> nctId: NCT06347432 id: 24-119-H briefTitle: Em-power: Maximizing Functional Independence for Children With Severe Cerebral Palsy overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2027-03 date: 2027-03 date: 2024-04-04 date: 2024-04-04 name: Grand Valley State University class: OTHER briefSummary: For ... |
<|newrecord|> nctId: NCT06347419 id: Iayas8 briefTitle: Body Awareness and Spinal Stability in Scoliosis overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2024-06-30 date: 2024-07-30 date: 2024-04-04 date: 2024-04-04 name: Gazi University class: OTHER briefSummary: Thirty volunteer patients diagnosed with scolio... |
The results obtained from this study will elucidate the relationship between body awareness and spinal stability in individuals with scoliosis. conditions: Scoliosis Idiopathic studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Physiotherapy evaluation measu... |
<|newrecord|> nctId: NCT06347406 id: FSKesihatan briefTitle: Effects of Combined Physiotherapy Management and Education overallStatus: RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2025-04-01 date: 2024-04-04 date: 2024-04-04 name: Fakulti Sains Kesihatan class: OTHER briefSummary: This observational study aims to... |
* Are there any effects of combined physiotherapy program among individuals with PFPS on: |
i) Pain ii) Muscle functions (strength, muscle bulk, flexibility) iii) Knee muscle functional performance (anteromedial lunge, step-down, bilateral squat, and balance and reach) iv) Kinesiophobia v) Quality of life Participants will be |
* Measure for the anthropometrics data including body weight, height, and BMI. |
* Answer the Numerical Pain Rating scale |
* Abswe Malay version of KOOS-PF and TAMPA scale. |
* Once they finished with the questionnaire, the participants will be stationed into station 1 (HDD), station 2 (Realtime Ultrasound) and station 3 (Dartfish Motion Analysis) Treatment they will receive |
* Blood flow restrictions cuff with physiotherapy exercises |
* Patient education Researcher will compare Blood flow exercises combined with physiotherapy exercises and education (Group A) with Physiotherapy exercises (Group B) to see if there is an effect on i) Pain ii) Muscle Functions (strength, muscle bulk, flexibility iii) Functional performance (anteromedial lunge, step-dow... |
<|newrecord|> nctId: NCT06347393 id: 6425 briefTitle: Transgender and Gender Diverse Individuals Screening for Breast Cancer acronym: GENESIS overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-03-31 date: 2026-03-31 date: 2024-04-04 date: 2024-04-24 name: Fondazione Policlinico Universitario Agostino Gemelli... |
<|newrecord|> nctId: NCT06347380 id: CIP011 briefTitle: Usability Study of the FemPulse System overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-08-30 date: 2024-08-30 date: 2024-04-04 date: 2024-04-04 name: FemPulse Corporation class: INDUSTRY briefSummary: The objective of the study is to demonstrate that... |
<|newrecord|> nctId: NCT06347367 id: EU-FTR-GK-01 briefTitle: Short-term Effect of Exercise and Self-manual Approaches to Bloating - Distention overallStatus: RECRUITING date: 2023-01-01 date: 2024-04-17 date: 2024-04-19 date: 2024-04-04 date: 2024-04-04 name: Ege University class: OTHER briefSummary: Abdominal bloatin... |
<|newrecord|> nctId: NCT06347354 id: CRO-2024-15 briefTitle: Permanence of Indocyanine Green in Axillary Lymph Nodes 3 Weeks After Subdermal Injection in Patients With Breast Cancer and Metastatic Lymph Nodes acronym: FLUO overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2025-08 date: 2025-08 date: 2024-04-04 date... |
<|newrecord|> nctId: NCT06347341 id: 2019-A02014-53 briefTitle: GlutN : Randomized, Double-blind, Crossover Clinical Trial to Confirm the Role of Gluten in Non-celiac Gluten Sensitivity acronym: GLUTN overallStatus: TERMINATED date: 2021-10-27 date: 2023-03-24 date: 2023-03-24 date: 2024-04-04 date: 2024-04-04 name: Un... |
<|newrecord|> nctId: NCT06347328 id: 23-AOI-01 briefTitle: The Benefits of Posterior Joint Infiltration in Chronic Low Back Pain acronym: InCHO overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2027-01 date: 2027-03 date: 2024-04-04 date: 2024-04-05 name: Centre Hospitalier Universitaire de Nice class: OTHER briefS... |
Low back pain is the most common form of spinal pain, more chronic and severe than cancer pain. The annual prevalence of chronic low back pain ranges from 15% to 45% (one-off prevalence, 30%; lifetime prevalence, 54-80%). Because of this extremely high incidence, doctors from a wide range of specialities perform interv... |
Facet joints have long been recognised as a source of back pain. In 1911, Goldthwait first recognised their role as a potential source of back pain. In 1933, Ghormley introduced the term "facet syndrome", defining lumbosacral pain with or without radicular pain. Badgley later suggested that facet joints could be a prim... |
The management of chronic low back pain due to zygapophyseal involvement (lumbar facet joints) consists primarily of conservative treatment. This is based on analgesics, anti-inflammatory drugs, physiotherapy and weight loss, where appropriate. Other non-surgical options may be proposed, including glucocorticoid inject... |
Traditionally, in routine clinical practice, if there is significant paravertebral contracture and the clinical signs point to posterior joint involvement, a glucocorticoid injection is given in the doctor's surgery at the time of consultation, using anatomical landmarks to guide needle placement. However, few studies ... |
With the advent of new imaging modalities such as ultrasound, more and more practitioners are turning to image-guided injections. To date, only the fluoroscopy-guided technique is considered reliable for facet joint infiltration. |
In order to improve the clinical efficacy of the various interventional therapeutic solutions, some authors have supported the use of ultrasound guidance. Several studies have been published comparing ultrasound-guided infiltration and infiltration using anatomical location in the shoulder region, the iliopsoas and in ... |
To our knowledge, no randomised, methodologically sound study has yet been carried out to compare the benefit of ultrasound-guided infiltration versus infiltration with anatomical location. |
The aim of our study is to show that ultrasound-guided zygoapophyseal infiltration is superior to anatomically-guided infiltration in terms of pain assessment. conditions: Chronic Low-back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOU... |
<|newrecord|> nctId: NCT06347315 id: 2302.CLI briefTitle: Evaluation of the Effects of a Nutritional Intervention of Ketogenic Medium-chain Triglycerides and B-vitamins on Cognitive Functioning in Older Adults With Mild Cognitive Impairment (COGNIKET-MCI) overallStatus: NOT_YET_RECRUITING date: 2024-05-10 date: 2027-12... |
<|newrecord|> nctId: NCT06347302 id: EID 2023 briefTitle: Study of Vitreoretinal Molecular Changes During Rhegmatogenous Retinal Detachment acronym: LIPIDRET overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-10 date: 2025-10 date: 2024-04-04 date: 2024-04-04 name: Centre Hospitalier Universitaire Dijon class: ... |
It is an ophthalmological emergency that threatens visual acuity and requires surgery. However, despite satisfactory post-operative anatomical results, vitreoretinal proliferation and photoreceptor death can still have a negative impact on visual prognosis. These complications are still not fully understood. |
A previous study carried out by the Eye, Nutrition and Cell Signalling team at the CSGA, comparing mouse models of retinal detachment with healthy control retinas, revealed an increase in pro-inflammatory cytokines and a change in retinal lipid abundance in detached retinas. |
However, these results have yet to be confirmed in humans. Our main hypothesis is that the vitreous content of omega-3 PUFAs and proteins is altered during the onset of retinal detachment, since it reflects both intraocular inflammation and photoreceptor apoptosis. |
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