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A possible solution to this problem exists in a validated app (SelfBack) that provides tailored self-management plans consisting of advice on physical activity, physical exercises, and educational content. Tailoring of treatment plans to individuals is achieved by using case-based reasoning (CBR) methodology which is a... |
This study will evaluate the feasibility of distributing the SelfBack app to persons experiencing LBP through their chiropractors. |
The results of this study will help us understand the barriers and facilitators of distributing and using the app through Alberta Chiropractors. This information will be used to apply for funding for a larger study to understand the effectiveness of the app as an intervention for persistent and recurrent LBP. condition... |
<|newrecord|> nctId: NCT06347978 id: 24-41296 briefTitle: Personalized DBS for OCD Guided by Stereoencephalography Mapping overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2028-04 date: 2028-04 date: 2024-04-04 date: 2024-04-04 name: Andrew Moses Lee, MD, PhD class: OTHER briefSummary: This is a double-blinded, ra... |
<|newrecord|> nctId: NCT06347965 id: IIT20220541B-R1 briefTitle: Construction and Effect Evaluation of the Low Load Blood Flow Restriction Training Program for Lung Cancer Patients Complicated With Sarcopenia During Chemotherapy overallStatus: COMPLETED date: 2023-02-01 date: 2023-11-30 date: 2024-02-20 date: 2024-04-0... |
The main questions it aims to answer are: |
Can low load blood flow restriction training improve sarcopenia in chemotherapy induced lung cancer patients? Which training method is more effective and tolerable between low load blood flow restriction training and progressive resistance training? |
Participants will be randomly divided into 3 groups： |
1. Routine care group (Control group, CON): The researchers will provide participants with regular exercise and dietary guidance. |
2. Low load blood flow restriction group (LL-BFRT): The researchers will provide participants with a low load blood flow restriction training program constructed by our research group. |
3. Progressive resistance training group (PRE): The researchers will provide participants with progressive resistance training. conditions: Sarcopenia conditions: Lung Neoplasms studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE whoMas... |
<|newrecord|> nctId: NCT06347952 id: SE1188 briefTitle: Mapping Arterial Perforators Within the Breast During Mammoplasty acronym: Map-total overallStatus: COMPLETED date: 2022-04-27 date: 2024-01-25 date: 2024-01-29 date: 2024-04-04 date: 2024-04-04 name: Royal Marsden NHS Foundation Trust class: OTHER briefSummary: B... |
In moving the NAC, the surgeon must ensure an adequate blood supply is maintained to preserve nourishment of the NAC tissue otherwise it can die (necrose) resulting in its removal. The tissue carrying the blood supply is known as a 'pedicle' and is fashioned by the surgeon for each patient during surgery. |
We know as surgeons, that in most areas of anatomy of the human body there are variations in the pattern of blood vessels. The NAC blood supply is no exception. Yet for each individual patient, the only way to safely know these anatomical patterns is to map them before or during surgery. |
A surgical tool utilising an aspect of ultrasound (known as doppler) is often used to locate visually (or by hearing) blood flow from blood vessels in operations where such knowledge is critical to the success of the procedure (for example DIEP-based breast reconstruction or chest wall perforator flaps). |
We would like to evaluate the effectiveness of the routine use of doppler for NAC preservation during mammoplasty procedures to see if it gives the consultant surgeon and/or trainee a greater degree of confidence when shaping the NAC pedicle to preserve its blood supply. |
In addition, we evaluate the training potential of patients undergoing symmetrising breast reduction, whereby the tissue removed is first mapped using acoustic doppler as for the NAC above. conditions: Breast Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 80 type: ACTUAL ... |
<|newrecord|> nctId: NCT06347939 id: 2023-06638-01 briefTitle: Mediastinal EBUS Cryobiopsy Study In Sweden acronym: MECRIS overallStatus: RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2028-12-31 date: 2024-04-04 date: 2024-04-19 name: Region Skane class: OTHER briefSummary: This study is a prospective observationa... |
Follow up four weeks after the procedure to assess the risk for postoperative complications. conditions: Mediastinal Lymphadenopathy conditions: Lung Cancer conditions: Sarcoidosis conditions: Lymphoma conditions: Tuberculosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 t... |
<|newrecord|> nctId: NCT06347926 id: PROICM 2023-11 EVA briefTitle: Evaluation of the Effect of Photobiomodulation on Sexual Quality of Life in Women With Breast Cancer acronym: EVABIOSEIN overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-08 date: 2025-08 date: 2024-04-04 date: 2024-04-04 name: Institut du Can... |
Sexual health is a crucial component of well-being and overall quality of life. Vaginal dryness and dyspareunia are symptoms frequently found in patients treated for breast cancer, with chemotherapy and hormone therapy as risk factors. However, the treatment of sexual disorders remains underdeveloped in France. |
Vaginal dryness is part of a broader syndrome known as genitourinary syndrome of menopause (GSM), or vulvovaginal atrophy, which may combine vulvovaginal (dryness, irritation, burning), sexual (dyspareunia) and urinary (infections, pollakiuria, urgency) symptoms secondary to hypoestrogenemia, exacerbated by breast canc... |
<|newrecord|> nctId: NCT06347913 id: Soh-Med-24-03-09MS briefTitle: Umblical Artery Systolic \Diastolic Ratio and Amniotic Fluid Index in Prediction of Fetal Outcome in Term Pregnancy overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-08 date: 2025-03 date: 2024-04-04 date: 2024-04-04 name: Sohag University cla... |
<|newrecord|> nctId: NCT06347900 id: Soh-Med-23-09-7PD briefTitle: Corneal Topographic Changes in Different Grades of OSA overallStatus: RECRUITING date: 2024-01-01 date: 2024-04-30 date: 2024-06-30 date: 2024-04-04 date: 2024-04-04 name: Sohag University class: OTHER briefSummary: Corneal topographic parameters in dif... |
<|newrecord|> nctId: NCT06347887 id: SGI-PCR-01 briefTitle: Clinical Validation of ColonAiQ (a Blood-based Assay Targeting ctDNA Methylation) for Colorectal Cancer Detection overallStatus: COMPLETED date: 2021-05-31 date: 2024-01-16 date: 2024-01-16 date: 2024-04-04 date: 2024-04-04 name: Singlera Genomics Inc. class: ... |
<|newrecord|> nctId: NCT06347874 id: ANES-2024-32820 briefTitle: Cryo Rib Fracture Study overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-31 date: 2026-11-30 date: 2024-04-04 date: 2024-04-04 name: University of Minnesota class: OTHER briefSummary: The purpose of this study is to determine if patients w... |
<|newrecord|> nctId: NCT06347861 id: C4891003 briefTitle: A Study to Learn How Various Tablets of the Study Medicine Vepdegestrant Are Taken up Into the Blood of Healthy Adults overallStatus: RECRUITING date: 2024-04-02 date: 2024-06-16 date: 2024-07-05 date: 2024-04-04 date: 2024-04-16 name: Pfizer class: INDUSTRY nam... |
This study looks at how the medicine is changed and removed from the body after a participant takes it. |
This study is seeking for participant who: |
* are healthy males, and healthy females who do not have the possibility to have children. |
* are 18 years of age or older. |
* weigh more than 45 Kilograms (99 pounds). |
The study consists of 3 treatments. Each participant will be assigned by chance to receive the 3 treatments in a certain sequence. This will be done over 3 study periods. Each treatment consists of a single amount of vepdegestrant taken by mouth in each study period. There will be a washout period between each study pe... |
<|newrecord|> nctId: NCT06347848 id: IstanbulUCKA briefTitle: The Effect of Psychoeducation Focused on Reducing Internalized Stigma overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2024-05-01 date: 2024-09-01 date: 2024-04-04 date: 2024-04-04 name: Istanbul University - Cerrahpasa (IUC) class: OTHER briefSummar... |
<|newrecord|> nctId: NCT06347835 id: Gut-Intervention-SAR-2024 briefTitle: Biomarker Identification and Nutritional Intervention of Primary Sarcopenia Based on Gut-muscle Axis overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2026-01 date: 2024-04-04 date: 2024-04-22 name: Peking Union Medical College... |
<|newrecord|> nctId: NCT06347822 id: 23-011276 briefTitle: Increasing Access to Evidence-Based Care in Integrated Behavioral Health overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-10 date: 2024-10 date: 2024-04-04 date: 2024-04-04 name: Mayo Clinic class: OTHER briefSummary: The purpose of this research is t... |
<|newrecord|> nctId: NCT06347809 id: 18-006343 id: NCI-2024-01225 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: 18-006343 type: OTHER domain: Mayo Clinic Institutional Review Board briefTitle: DNA Methylation in Adenocarcinoma of the Prostate: Analysis of Validated Biomarkers in Urine overallStatus... |
<|newrecord|> nctId: NCT06347796 id: 23-0160 id: 1UG3NS128397-01A1 type: NIH link: https://reporter.nih.gov/quickSearch/1UG3NS128397-01A1 briefTitle: Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study acronym: CHESS overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2029-09 date: 2029-09 date... |
* Compared to open conventional surgery, does MMAE reduce the need for rescue surgery or deaths? |
* What is the safety of MMAE and conventional open surgery in these patients? |
Participants will be asked to: |
* Share their medical history and undergo physical examinations |
* Have blood drawn |
* Have CT scans of the head |
* Answer questionnaires |
* Undergo MMAE or conventional open surgery |
* Provide information about possible adverse events Researchers will compare participants in the MMAE group with those in the conventional open surgery group to see if there is a reduced need for rescue surgery or deaths and evaluate safety. conditions: Chronic Subdural Hematoma studyType: INTERVENTIONAL phases: NA all... |
<|newrecord|> nctId: NCT06347783 id: STUDY00026893 briefTitle: Automated Insulin Delivery vs. Injections: Sleep Impact in Pediatric Type 1 Diabetes overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2024-11-15 date: 2024-12-15 date: 2024-04-04 date: 2024-04-04 name: Oregon Health and Science University class: OTH... |
The goal of this observational study is learn about the effect of insulin pumps on sleep in pediatric patients with type 1 diabetes and their caregivers. The main questions it aims to answer are: |
Do insulin pumps improve sleep, worsen sleep or have no effect at all? What is the relationship between insulin pumps, sleep, and overnight blood sugar control? |
Participants will be asked to: |
* Complete questionnaires regarding demographic data and diabetes history. |
* Complete surveys regarding sleep quality before and after starting an insulin pump. |
* Wear a FitBit during sleep for 2 weeks and fill out daily sleep diaries over a 2 week period prior to starting an insulin pump. |
After 1-2 months after initiation of an insulin pump, participants will be asked again to: |
* Complete surveys regarding sleep quality |
* Wear a FitBit during sleep for 2 weeks |
* Fill out daily sleep diaries over the same 2 week period. conditions: Type1diabetes studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 80 type: ESTIMATED name: Insulin pump measure: Sleep duration measure: Sleep efficiency measure: Sleep Disturbance Scale for Children measure: Pro... |
<|newrecord|> nctId: NCT06347770 id: ThirdSunYat-senECII202329903 briefTitle: Effect of Probiotics Before Cesarean Section on Postoperative Recovery in Pregnant Women overallStatus: RECRUITING date: 2023-11-01 date: 2025-10 date: 2025-10 date: 2024-04-04 date: 2024-04-08 name: Third Affiliated Hospital, Sun Yat-Sen Uni... |
<|newrecord|> nctId: NCT06347757 id: NorthernJiangsuhospital1 briefTitle: A 3-Arm Study Comparing the Efficacy of Anti-Reflux Reconstruction Protocols After Laparoscopic Proximal Gastrectomy overallStatus: COMPLETED date: 2020-01-01 date: 2023-12-31 date: 2024-03-15 date: 2024-04-04 date: 2024-04-04 name: Northern Jian... |
<|newrecord|> nctId: NCT06347744 id: RADX-P-2401 briefTitle: Radicle Rest 24: A Study of Health and Wellness Products on Sleep and Related Health Outcomes overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2024-09 date: 2024-12 date: 2024-04-04 date: 2024-04-08 name: Radicle Science class: INDUSTRY briefSummary: A r... |
<|newrecord|> nctId: NCT06347731 id: VAR-2024-01 briefTitle: Varian ProBeam360° Proton Therapy System China Clinical Trial (Wuhan) overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2025-03 date: 2025-03 date: 2024-04-04 date: 2024-04-17 name: Varian, a Siemens Healthineers Company class: INDUSTRY briefSummary: This... |
<|newrecord|> nctId: NCT06347718 id: CASTLE id: 2022-001366-35 type: EUDRACT_NUMBER id: DRKS00032279 type: REGISTRY domain: Deutsches Register Klinischer Studien (DRKS) briefTitle: CAR-T Cells in Systemic B Cell Mediated Autoimmune Disease acronym: CASTLE overallStatus: RECRUITING date: 2023-07-17 date: 2026-05-31 date... |
Evaluating the safety of CAR-T-Cells in systemic autoimmune diseases with 8 patients |
Phase 2: |
Evaluating the efficiency of CAR-T-Cells in systemic autoimmune diseases with 16 patients primaryPurpose: TREATMENT masking: NONE count: 24 type: ESTIMATED name: anti-CD19 CAR T cell therapy measure: To assess the safety of anti-CD19 CAR T cell therapy in subjects with active B-driven autoimmune disease (SLE, SSc and D... |
<|newrecord|> nctId: NCT06347705 id: 23-252 briefTitle: A Study of 2141-V11 in Combination With Standard Treatments in People With Prostate Cancer overallStatus: RECRUITING date: 2024-03-28 date: 2029-03-28 date: 2029-03-28 date: 2024-04-04 date: 2024-04-05 name: Memorial Sloan Kettering Cancer Center class: OTHER brie... |
<|newrecord|> nctId: NCT06347692 id: SCBR-240/2024 briefTitle: Effect of Antigravity Treadmill in Knee Osteoarthritis (AGTreadmill) acronym: AGTreadmill overallStatus: NOT_YET_RECRUITING date: 2024-04-07 date: 2024-04-20 date: 2025-04-20 date: 2024-04-04 date: 2024-04-04 name: Prince Sattam Bin Abdulaziz University cla... |
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