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11,462,906 | Clinicopathological analyses of advanced colorectal cancers of different sizes--especially those of 20 mm or less in diameter. | Hepato-gastroenterology | Hepatogastroenterology | 48 | 39 | null | eng | 2,001 | null | null | null | null | null | [BACKGROUND/AIMS] Many small cancers of the flat type can now be detected, and many advanced cancers of the flat type have been discovered. In this study, to clarify the clinicopathological characteristics of small advanced cancers, advanced cancers of 20 mm or less in diameter were compared with those of other sizes. ... | null | 0.529 | 84 | Medicine; Gastroenterology; Hepatology | Medicine | 2,001 |
11,461,871 | Sonographically guided directional vacuum-assisted breast biopsy using a handheld device. | AJR. American journal of roentgenology | AJR Am J Roentgenol | 177 | 2 | 10.2214/ajr.177.2.1770405 | eng | 2,001 | 8 | null | null | null | null | [OBJECTIVE] The goal of this study was to show that one can safely remove all sonographic evidence of masses in the breast less than or equal to 1.5 cm in greatest dimension using the 11-gauge handheld Mammotome, thereby reducing the possibility of a false-negative diagnosis and other shortcomings of the automated core... | null | null | null | null | null | null |
11,460,934 | CO2 laser surgery in otorhinolaryngology-site and complications: a 10-year experience at Ramathibodi Hospital. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet | J Med Assoc Thai | 84 | 3 | null | eng | 2,001 | 3 | null | null | null | null | [OBJECTIVE] To present data on ten years' experience in CO2 laser surgery and associated complications among otorhinolayngologic patients. [MATERIAL AND METHOD] The study involved examining records of otorhinolaryngologic patients who underwent CO2 laser operations during a 10-year period (July 1, 1986-June 30, 1996). ... | null | null | null | null | null | null |
11,459,897 | Can item response theory reduce patient burden when measuring health status in neurological disorders? Results from Rasch analysis of the SF-36 physical functioning scale (PF-10). | Journal of neurology, neurosurgery, and psychiatry | J Neurol Neurosurg Psychiatry | 71 | 2 | 10.1136/jnnp.71.2.220 | eng | 2,001 | 8 | null | null | null | null | [BACKGROUND] Indices of physical function may have a hierarchy of items. In cases where this can be demonstrated it may be possible to reduce patient burden by asking them to complete only those items which relate directly to their own level of ability. [OBJECTIVES] To determine whether statistical procedures, operatio... | null | 1.228 | 244 | Neurology; Psychiatry and Mental Health; Surgery | Medicine | 2,001 |
11,459,890 | Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations. | Journal of neurology, neurosurgery, and psychiatry | J Neurol Neurosurg Psychiatry | 71 | 2 | 10.1136/jnnp.71.2.188 | eng | 2,001 | 8 | null | null | null | null | [OBJECTIVES] Cerebral cavernous malformations are linked to mutations of the KRIT1 gene at the CCM1 locus and to mutations at two other loci, CCM2 and CCM3, for which genes are not yet identified. There is little information regarding the function of KRIT1. Histological and immunocytochemical analysis of cavernous malf... | null | 1.228 | 244 | Neurology; Psychiatry and Mental Health; Surgery | Medicine | 2,001 |
11,459,235 | Body mass index of adult males in 12 populations of northeast India. | Annals of human biology | Ann Hum Biol | 28 | 4 | 10.1080/03014460010004610 | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Of the anthropometric indices, body mass index (BMI) is considered to be more nutritionally than genetically related. Thus, in a country with diverse ethnic groups like India, it is more appropriate to use BMI as an indicator of the nutritional status of adult population. However, literature on BMI of adul... | null | 0.565 | 70 | Public Health, Environmental and Occupational Health; Aging; Epidemiology; Genetics; Physiology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,458,594 | Is it time to include the practice nurse in integrated primary health care? | Australian family physician | Aust Fam Physician | 30 | 6 | null | eng | 2,001 | 6 | null | null | null | null | [BACKGROUND] The new '700 series' Medical Benefit Schedule (MBS) items for general practice introduce greatly increased potential for collaboration between general practitioners and other health professionals in patient care. [AIM] To investigate the current perceptions of Australian GPs with respect to the desirabilit... | null | null | null | null | null | null |
11,458,158 | Intraspinal metallosis causing delayed neurologic symptoms after spinal instrumentation surgery. | Spine | Spine (Phila Pa 1976) | 26 | 13 | 10.1097/00007632-200107010-00024 | eng | 2,001 | 7 | 1 | null | null | null | [STUDY DESIGN] Two cases of intraspinal metallosis causing delayed neurologic symptoms secondary to spinal instrumentation surgery are reported. [OBJECTIVE] To present an unusual delayed neurologic complication after spinal instrumentation surgery. [SUMMARY OF BACKGROUND DATA] Metal-related complications caused by orth... | null | 1.078 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,001 |
11,458,136 | Does managed care enable more low income persons to identify a usual source of care? Implications for access to care. | Medical care | Med Care | 39 | 7 | 10.1097/00005650-200107000-00008 | eng | 2,001 | 7 | null | null | null | null | [BACKGROUND] By requiring or encouraging enrollees to obtain a usual source of care, managed care programs hope to improve access to care without incurring higher costs. [OBJECTIVES] (1) To examine the effects of managed care on the likelihood of low-income persons having a usual source of care and a usual physician, a... | null | 1.879 | 207 | Public Health, Environmental and Occupational Health | Medicine | 2,001 |
11,458,127 | Antihypertensive drugs induce structural remodeling of the penile vasculature. | The Journal of urology | J Urol | 166 | 2 | null | eng | 2,001 | 8 | null | null | null | null | [PURPOSE] There is a strong association between hypertension and erectile dysfunction. Studies of the treatment of hypertension have shown that some pharmacological agents are capable of inducing regression of the vascular structure during treatment. We determined whether penile vascular structure is as susceptible as ... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,458,122 | Effects of sodium hyaluronate on epithelial healing of the vesical mucosa and vesical fibrosis in rabbits with acetic acid induced cystitis. | The Journal of urology | J Urol | 166 | 2 | null | eng | 2,001 | 8 | null | null | null | null | [PURPOSE] To evaluate the effect of sodium hyaluronate on epithelial healing of the vesical mucosa and vesical fibrosis, and clarify the effect of the sodium hyaluronate solution concentration, we administered sodium hyaluronate in the bladder of rabbits with acetic acid induced cystitis. [MATERIALS AND METHODS] Sodium... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,458,115 | Co-localization of androgen receptor with estrogen receptor beta in the lower urinary tract of the male rat. | The Journal of urology | J Urol | 166 | 2 | null | eng | 2,001 | 8 | null | null | null | null | [PURPOSE] Androgens and estrogens influence voiding. In this study their target sites in the lower urinary tract of the male rat were identified. [MATERIALS AND METHODS] Cryosections of the bladder body, bladder neck, prostatic urethra, mid proximal urethra and prostatic autonomic ganglia of adult male rats were immuno... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,458,058 | Adult prostate sarcoma: the M. D. Anderson Cancer Center Experience. | The Journal of urology | J Urol | 166 | 2 | 10.1016/s0022-5347(05)65974-5 | eng | 2,001 | 8 | null | null | null | null | [PURPOSE] Sarcoma of prostate origin is rare. Historically, long-term survival rates for adult patients with prostate sarcoma are poor. We analyzed the experience of 1 institution with prostate sarcoma during the last 3 decades. [MATERIALS AND METHODS] The records of 21 patients with prostate sarcoma were reviewed to i... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,458,056 | A structured debate: immediate versus deferred androgen suppression in prostate cancer-evidence for deferred treatment. | The Journal of urology | J Urol | 166 | 2 | 10.1016/s0022-5347(05)65972-1 | eng | 2,001 | 8 | null | null | null | null | [PURPOSE] We present a structured debate supporting the premise that immediate hormonal intervention has not been conclusively shown to provide a survival advantage in the management of advanced prostate cancer. [MATERIALS AND METHODS] The literature emphasizing randomized trials was reviewed. Recommendations are based... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,458,047 | Clinical significance of denuded urothelium in bladder biopsy. | The Journal of urology | J Urol | 166 | 2 | null | eng | 2,001 | 8 | null | null | null | null | [PURPOSE] Although to our knowledge the significance of denuded urothelium in bladder biopsies has not been studied previously, it is thought to be a problem because benign urothelial cells are cohesive and not expected to shed into the urine. We correlated the pertinent clinical features of patients with denuded bladd... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,458,045 | Long-term followup after laparoscopic nephropexy for symptomatic nephroptosis. | The Journal of urology | J Urol | 166 | 2 | null | eng | 2,001 | 8 | null | null | null | null | [PURPOSE] Symptomatic nephroptosis is a rare disease requiring surgical therapy only in select cases. Laparoscopic nephropexy has been reported as minimally invasive treatment for symptomatic patients. We evaluated our long-term outcome after laparoscopic fixation of the kidney with an alloplastic mesh graft. [MATERIAL... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,457,755 | Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase. | Circulation | Circulation | 104 | 3 | 10.1161/01.cir.104.3.342 | eng | 2,001 | 7 | 17 | null | null | null | [BACKGROUND] Insulin resistance and arterial hypertension are related, but the underlying mechanism is unknown. Endothelial nitric oxide synthase (eNOS) is expressed in skeletal muscle, where it may govern metabolic processes, and in the vascular endothelium, where it regulates arterial pressure. [METHODS AND RESULTS] ... | null | 5.548 | 691 | Cardiology and Cardiovascular Medicine; Physiology | Medicine | 2,001 |
11,457,634 | Acceptability of the Checkpoints Parent-Teen Driving Agreement: pilot test. | American journal of preventive medicine | Am J Prev Med | 21 | 2 | 10.1016/s0749-3797(01)00330-0 | eng | 2,001 | 8 | null | null | null | null | [BACKGROUND] Parent-teen driving agreements are potentially important tools to facilitate parental management of teen driving and reduce adolescent driving risk. The Checkpoints Parent-Teen Driving Agreement (Checkpoints P-TDA) was designed so that parents could initially impose strict limitations on teen driving in hi... | null | 1.578 | 260 | Epidemiology; Public Health, Environmental and Occupational Health | Medicine | 2,001 |
11,456,228 | Smoking and hematolymphopoietic malignancies. | Cancer causes & control : CCC | Cancer Causes Control | 12 | 4 | 10.1023/a:1011216102871 | eng | 2,001 | 5 | null | null | null | null | [OBJECTIVE] Tobacco use is the most prominent cause of respiratory cancers. Little is known, however, about the influence of smoking on hematolymphopoietic malignancies. To evaluate this relation, a population-based case-control study was carried out in 12 areas of Italy. [METHODS] Detailed interviews on tobacco smokin... | null | null | null | null | null | null |
11,456,028 | Progressive outer retinal necrosis syndrome: successful treatment with a new combination of antiviral drugs. | European journal of ophthalmology | Eur J Ophthalmol | 11 | 2 | 10.1177/112067210101100220 | eng | 2,001 | null | null | null | null | null | [PURPOSE] To describe a case of progressive outer retinal necrosis syndrome, successfully treated with a new combination of antiviral drugs. [METHODS] The patient was treated with a combined therapy of antiviral drugs that includes: intravenous acyclovir 10 mg/kg, three intravitreal injections of foscarnet (1200 microg... | null | 0.532 | 69 | Medicine; Ophthalmology | Medicine | 2,001 |
11,456,002 | Trends in births to parents of two different races in the United States: 1971-1995. | Ethnicity & disease | Ethn Dis | 11 | 2 | null | eng | 2,001 | null | null | null | null | null | [PURPOSE] In 1997, the Office of Management and Budget (OMB) introduced revised standards for classification of federal data on race. The new standards include the option to report more than one race. Reasons for the new standards include a change over time in childbearing patterns by race. [OBJECTIVE] To better unders... | null | null | null | null | null | null |
11,455,733 | Perioperative treatment with bactericidal/permeability-increasing protein (rBPI21) in major liver surgery: a concise summary. | Annals of the Academy of Medicine, Singapore | Ann Acad Med Singap | 30 | 3 | null | eng | 2,001 | 5 | null | null | null | null | [INTRODUCTION] Major hepatic resections are still associated with considerable morbidity. Gut-derived bacteria and bacterial endotoxin are considered to play a central role in the pathophysiology of complications. Experimental studies suggest that bactericidal/permeability-increasing protein (BPI), which has both antib... | null | 0.187 | 70 | Medicine | Medicine | 2,001 |
11,455,292 | Femoral vein valve repair with angioscopy-assisted anterior valve sinus plication. Early results. | The Journal of cardiovascular surgery | J Cardiovasc Surg (Torino) | 42 | 4 | null | eng | 2,001 | 8 | null | null | null | null | [BACKGROUND] The efficiency of angioscopy-assisted anterior valve sinus plication for primary deep venous insufficiency was evaluated. [EXPERIMENTAL DESIGN] retrospective, clinical study with short follow-up. [SETTING] institutional practice. [PATIENTS] 15 limbs in 12 patients had class 4 or higher disease (SVS/ISCVS c... | null | 0.339 | 59 | Cardiology and Cardiovascular Medicine; Medicine; Surgery | Medicine | 2,001 |
11,455,257 | Results of a randomized, prospective, multicenter trial of mycophenolate mofetil versus azathioprine in the prevention of acute lung allograft rejection. | Transplantation | Transplantation | 71 | 12 | 10.1097/00007890-200106270-00012 | eng | 2,001 | 6 | 27 | null | null | null | [BACKGROUND] Although the use of mycophenolate mofetil (MMF) has reduced the incidence of acute rejection in heart and kidney allograft recipients, its role in lung transplantation remains controversial. Therefore, we conducted a randomized, prospective, open-label, multicenter study in lung transplant recipients to de... | null | 1.782 | 224 | Transplantation | Medicine | 2,001 |
11,455,225 | Which factors render cost-covering lump-sum charging difficult for the treatment of patients with acute leukemias? | Onkologie | Onkologie | 24 | 3 | 10.1159/000055095 | eng | 2,001 | 6 | null | null | null | null | [BACKGROUND] Growing budget limitations and the planned charging subject to Diagnosis-Related Groups (DRG) points raise the question as to what costs are incurred by the induction therapy and early consolidation treatment of patients with acute myeloid leukemias (AML) and whether these can be compensated in a cost-cove... | null | null | 16 | Hematology; Oncology | Medicine | 2,001 |
11,454,798 | SOX10 is abnormally expressed in aganglionic bowel of Hirschsprung's disease infants. | Gut | Gut | 49 | 2 | 10.1136/gut.49.2.220 | eng | 2,001 | 8 | null | null | null | null | [BACKGROUND] The primary pathology of Hirschsprung's disease (HD) is a congenital absence of ganglion cells in the caudal most gut. The spastic aganglionic bowel is often innervated by a network of hypertrophied nerve fibres. Recently, mutations of SOX10 have been identified in patients with HD but only in those with W... | null | 2.014 | 364 | Gastroenterology | Medicine | 2,001 |
11,454,496 | Path analysis and multi-criteria decision making: an approach for multivariate model selection and analysis in health. | Annals of epidemiology | Ann Epidemiol | 11 | 6 | 10.1016/s1047-2797(01)00232-0 | eng | 2,001 | 8 | null | null | null | null | [PURPOSE] This paper introduces an approach that includes non-quantitative factors for the selection and assessment of multivariate complex models in health. [METHODS] A goodness-of-fit based methodology combined with fuzzy multi-criteria decision-making approach is proposed for model selection. Models were obtained us... | null | 1.132 | 145 | Epidemiology | Medicine | 2,001 |
11,454,043 | Reduced expression of p21WAF1 is an indicator of malignant behaviour in anal carcinomas. | Histopathology | Histopathology | 39 | 1 | 10.1046/j.1365-2559.2001.01161.x | eng | 2,001 | 7 | null | null | null | null | [AIMS] p21 and p27 protein expression were examined in a comparatively large series of patients with squamous cell carcinoma of the anal canal and compared with clinical and histopathological data (tumour stage, nodal status and differentiation). [METHODS AND RESULTS] We analysed the expression of p21 and p27 protein i... | null | 0.923 | 145 | Histology; Medicine; Pathology and Forensic Medicine | Medicine | 2,001 |
11,453,404 | Detection of simian virus 40 DNA sequence in human primary glioblastomas multiforme. | Journal of neurosurgery | J Neurosurg | 95 | 1 | 10.3171/jns.2001.95.1.0096 | eng | 2,001 | 7 | null | null | null | null | [OBJECT] Deoxyribonucleic acid oncoviruses can induce neoplastic transformation of cells because their viral proteins interfere with antiproliferative cellular proteins. Simian virus 40 (SV40) is a DNA virus that induces the emergence of ependymomas, choroid plexus tumors, mesotheliomas, osteosarcomas, sarcomas, and va... | null | 1.482 | 244 | Neurology; Surgery | Medicine | 2,001 |
11,453,328 | PBS/RPBS cost implications of trends and guideline recommendations in the pharmacological management of hypertension in Australia, 1994-1998. | The Medical journal of Australia | Med J Aust | 174 | 11 | 10.5694/j.1326-5377.2001.tb143436.x | eng | 2,001 | 6 | 4 | null | null | null | [OBJECTIVES] To determine the extent to which "current guidelines" for the management of hypertension are reflected in the prescribing of antihypertensive drugs in Australia over the period 1994-1998, and to examine the cost implications of actual and recommended prescribing patterns. [DESIGN] Federal Government and co... | null | 0.593 | 156 | Medicine | Medicine | 2,001 |
11,453,156 | A clinical minimum data set for primary dental care. | British dental journal | Br Dent J | 190 | 12 | 10.1038/sj.bdj.4801069 | eng | 2,001 | 6 | 23 | null | null | null | [OBJECTIVE] To achieve consensus within primary dental care on the contents of a clinical minimum data set to measure oral health status. [DESIGN] Using the Delphi process a simple random sample of 30 LDCs and 10 CDS services in England were asked to rank a list of existing clinical indicators in order of their perceiv... | null | null | null | null | null | null |
11,452,568 | Clinical decisions in the use of acupuncture as an adjunctive therapy for osteoarthritis of the knee. | Alternative therapies in health and medicine | Altern Ther Health Med | 7 | 4 | null | eng | 2,001 | null | null | null | null | null | [OBJECTIVE] To determine whether demographic, medical history, or arthritis assessment data may influence outcome and rate of decay for patients with osteoarthritis treated with acupuncture. [DESIGN] Seventy-three persons with symptomatic osteoarthritis of the knee were recruited for this randomized controlled trial. B... | null | 0.315 | 78 | Complementary and Alternative Medicine; Medicine | Medicine | 2,001 |
11,451,842 | Prevention of nosocomial urinary tract infection in ICU patients: comparison of effectiveness of two urinary drainage systems. | Chest | Chest | 120 | 1 | 10.1378/chest.120.1.220 | eng | 2,001 | 7 | null | null | null | null | [STUDY OBJECTIVES] To determine whether the rate of acquisition of bacteriuria differs between the use of a complex closed drainage system (CCDS) with a preattached catheter, antireflux valve, drip chamber, and povidone-iodine releasing cartridge, and a two-chamber open drainage system (TCOS) in ICU patients. [DESIGN] ... | null | 0.916 | 337 | Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,001 |
11,451,812 | Lung cancer treated surgically in patients <50 years of age. | Chest | Chest | 120 | 1 | 10.1378/chest.120.1.32 | eng | 2,001 | 7 | null | null | null | null | [STUDY OBJECTIVES] Some investigators have suggested that lung cancer in young patients has a more aggressive course and a poorer prognosis than lung cancer in older patients. The aim of this study was to determine if the basal characteristics and survival in younger patients with lung cancer undergoing surgical resect... | null | 0.916 | 337 | Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,001 |
11,451,318 | Cohort study of metastatic melanoma patients in the Dermatology Institute of Florence 1990/1997. | Journal of the European Academy of Dermatology and Venereology : JEADV | J Eur Acad Dermatol Venereol | 15 | 1 | 10.1046/j.1468-3083.2001.00197.x | eng | 2,001 | 1 | null | null | null | null | [BACKGROUND] Chemotherapy and immunotherapy are treatments currently employed in advanced melanoma, but responses obtained are poor, and metastatic melanoma patients with visceral localization rarely survive for more than 6 months. Thus, different therapeutic regimens are used in metastatic melanoma and no standardized... | null | 0.436 | 144 | Dermatology; Infectious Diseases | Medicine | 2,001 |
11,451,281 | Silent and clinically overt stroke in older Japanese subjects with white-coat and sustained hypertension. | Journal of the American College of Cardiology | J Am Coll Cardiol | 38 | 1 | 10.1016/s0735-1097(01)01325-0 | eng | 2,001 | 7 | null | null | null | null | [OBJECTIVES] We investigated whether white-coat hypertension is a risk factor for stroke in relation to silent cerebral infarct (SCI) in an older Japanese population. [BACKGROUND] It remains uncertain whether white-coat hypertension in older subjects is a benign condition or is associated with an increased risk of stro... | null | 4.039 | 512 | Cardiology and Cardiovascular Medicine | Medicine | 2,001 |
11,450,965 | Inpatient costs of routine endovascular repair of abdominal aortic aneurysm. | Academic radiology | Acad Radiol | 8 | 7 | 10.1016/S1076-6332(03)80689-X | eng | 2,001 | 7 | null | null | null | null | [RATIONALE AND OBJECTIVES] The purpose of this study was to determine the inpatient cost of routine (ie, without emergent conversion to open repair during the hospital stay) endovascular stent-graft placement in a consecutive series of patients undergoing elective endovascular repair of abdominal aortic aneurysm (AAA) ... | null | 0.607 | 113 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,001 |
11,450,962 | Analysis of uncertainties in estimates of components of variance in multivariate ROC analysis. | Academic radiology | Acad Radiol | 8 | 7 | 10.1016/S1076-6332(03)80686-4 | eng | 2,001 | 7 | null | null | null | null | [RATIONALE AND OBJECTIVES] Solutions have previously been presented to the problem of estimating the components of variance in the general linear model used for multivariate receiver operating characteristic (ROC) analysis. The case where the variance components do not change across the modalities under comparison was ... | null | 0.607 | 113 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,001 |
11,450,959 | A combined architectural and kinetic interpretation model for breast MR images. | Academic radiology | Acad Radiol | 8 | 7 | 10.1016/S1076-6332(03)80683-9 | eng | 2,001 | 7 | null | null | null | null | [RATIONALE AND OBJECTIVES] The purpose of this study was to integrate contrast material kinetic and architectural data from magnetic resonance (MR) images and to assess the improvement in diagnostic accuracy. [MATERIALS AND METHODS] MR imaging data from a diagnostic cohort of 100 patients (50 malignant and 50 benign ca... | null | 0.607 | 113 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,001 |
11,449,089 | Estradiol regulates monocyte chemotactic protein-1 in human coronary artery smooth muscle cells: a mechanism for its antiatherogenic effect. | Menopause (New York, N.Y.) | Menopause | 8 | 4 | 10.1097/00042192-200107000-00013 | eng | 2,001 | null | null | null | null | null | [OBJECTIVE] The protective effect of estrogen against early atherosclerosis in animal models is well documented, but the mechanisms responsible for this effect are not well understood. The earliest recognizable event in the pathogenesis of atherosclerosis is an increased recruitment of macrophages into the arterial sub... | null | 1.293 | 125 | Obstetrics and Gynecology | Medicine | 2,001 |
11,448,282 | The role of knee alignment in disease progression and functional decline in knee osteoarthritis. | JAMA | JAMA | 286 | 2 | 10.1001/jama.286.2.188 | eng | 2,001 | 7 | 11 | null | null | null | [CONTEXT] Knee osteoarthritis (OA) is a leading cause of disability in older persons. Few risk factors for disease progression or functional decline have been identified. Hip-knee-ankle alignment influences load distribution at the knee; varus and valgus alignment increase medial and lateral load, respectively. [OBJECT... | null | null | null | null | null | null |
11,447,389 | Roles of carbohydrates on Cry j 1, the major allergen of Japanese cedar pollen, in specific T-cell responses. | The Journal of allergy and clinical immunology | J Allergy Clin Immunol | 108 | 1 | 10.1067/mai.2001.115757 | eng | 2,001 | 7 | null | null | null | null | [BACKGROUND] Carbohydrates expressed on allergens are known to be important for allergenicity. However, little is known about whether the carbohydrates drive the T(H)2 response. [OBJECTIVE] We sought to determine a role for carbohydrates expressed on Cry j 1, which is the major allergen of Cryptomeria japonica pollen a... | null | 2.024 | 350 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,001 |
11,446,752 | Clinical and high-resolution computed tomographic findings in five patients with pulmonary tuberculosis who developed respiratory failure following chemotherapy. | Clinical radiology | Clin Radiol | 56 | 7 | 10.1053/crad.2000.0706 | eng | 2,001 | 7 | null | null | null | null | [AIM] The purpose of this study was to describe the clinical and high-resolution computed tomographic (HRCT) findings in patients with pulmonary tuberculosis who developed respiratory failure after starting chemotherapy. [MATERIALS AND METHODS] The clinical records, chest radiographs, and HRCT findings in five patients... | null | 0.653 | 110 | Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,001 |
11,446,711 | Genetic contribution to the variance in left ventricular mass: the Tecumseh Offspring Study. | Journal of hypertension | J Hypertens | 19 | 7 | 10.1097/00004872-200107000-00006 | eng | 2,001 | 7 | null | null | null | null | [OBJECTIVE] To estimate the contribution of heredity to the variance in left ventricular mass (LVM), and to ascertain whether genetic factors may interact with non-genetic factors in promoting LVM growth. [SUBJECTS AND SETTING] The study population consisted of 290 healthy parents and 251 healthy children living in Tec... | null | 1.649 | 198 | Cardiology and Cardiovascular Medicine; Internal Medicine; Physiology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,446,316 | Prognostic factors in glioblastoma multiforme. 10 years experience of a single institution. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] | Strahlenther Onkol | 177 | 6 | 10.1007/pl00002409 | eng | 2,001 | 6 | null | null | null | null | [BACKGROUND] To analyze prognostic factors in patients with a glioblastoma multiforme treated in an academic institute over the last 10 years. [PATIENTS AND METHOD] From 1988 to 1998, 198 patients with pathologically confirmed glioblastoma multiforme were analyzed. Five radiation schedules were used mainly based on pre... | null | 0.636 | 81 | Oncology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,001 |
11,446,128 | False-negative results in screening programs. Medical, psychological, and other implications. | International journal of technology assessment in health care | Int J Technol Assess Health Care | 17 | 2 | 10.1017/s0266462300105021 | eng | 2,001 | null | null | null | null | null | [OBJECTIVES] Assessment of the appropriateness of screening programs involves consideration of the harms as well as the benefits. These harms include the risk of false-negative results, the consequences of which have remained underinvestigated. This paper reports the results of a systematic literature review that aimed... | Empirical Approach; Health Care and Public Health | 0.495 | 79 | Health Policy | Medicine | 2,001 |
11,445,737 | Activated protein C versus protein C in severe sepsis. | Critical care medicine | Crit Care Med | 29 | 7 Suppl | 10.1097/00003246-200107001-00024 | eng | 2,001 | 7 | null | null | null | null | [OBJECTIVE] To delineate critical differences between activated protein C (APC) and its precursor, protein C, with regard to plasma levels in health and in severe sepsis, and to discuss the implications of these differences as they relate to treatment strategies in patients with severe sepsis. DATA SOURCE/STUDY SELECTI... | null | 0.763 | 315 | Critical Care and Intensive Care Medicine | Medicine | 2,001 |
11,444,416 | Potential antioxidant effects of zinc and chromium supplementation in people with type 2 diabetes mellitus. | Journal of the American College of Nutrition | J Am Coll Nutr | 20 | 3 | 10.1080/07315724.2001.10719034 | eng | 2,001 | 6 | null | null | null | null | [OBJECTIVE] To determine the effects of combined zinc (Zn) and chromium (Cr) supplementation on oxidative stress and glucose homeostasis of people with type 2 diabetes. [DESIGN] Tunisian adult subjects with HbA1C > 7.5% were supplemented for 6 months with 30 mg/d of Zn as Zn gluconate or 400 microg/d of Cr as Cr pidola... | null | 0.646 | 0 | Medicine; Nutrition and Dietetics | Medicine; Nursing | 2,001 |
11,444,194 | Prognostic value of DNA flow cytometry in sympathoadrenal paragangliomas. | Analytical and quantitative cytology and histology | Anal Quant Cytol Histol | 23 | 3 | null | eng | 2,001 | 6 | null | null | null | null | [OBJECTIVE] To determine whether ploidy patterns are related to prognosis in sympathoadrenal paragangliomas (SAP) using flow cytometry. [STUDY DESIGN] DNA flow cytometric analysis of formalin-fixed, paraffin-embedded tumor samples from 36 patients with SAP was performed. Eight cases fulfilled at least one of the follow... | null | null | null | null | null | null |
11,443,606 | No elevation in long-term breast carcinoma risk for women with fibroadenomas that contain atypical hyperplasia. | Cancer | Cancer | 92 | 1 | 10.1002/1097-0142(20010701)92:1<30::aid-cncr1288>3.0.co;2-2 | eng | 2,001 | 7 | 1 | null | null | null | [BACKGROUND] The authors previously showed that women with a fibroadenoma have a relative risk of invasive breast carcinoma of approximately 2.0 compared with women of similar age from the general population. This relative risk approaches 1.0 when family history and proliferative changes in the adjacent parenchyma are ... | null | 1.593 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,442,586 | Treatment of pyogenic granuloma with a sclerosing agent. | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] | Dermatol Surg | 27 | 6 | 10.1046/j.1524-4725.2001.01039.x | eng | 2,001 | 6 | null | null | null | null | [BACKGROUND] Pyogenic granulomas have been treated by cryosurgery, curettage, electrodesiccation, chemical cauterization, and laser surgery. The therapeutic effects of these conservative treatments are limited, however. [OBJECTIVE] In this study, the efficacy of a sclerosing agent (monoethanolamine oleate) was evaluate... | null | 0.852 | 146 | Dermatology; Medicine; Surgery | Medicine | 2,001 |
11,442,249 | Effective treatment of head and neck squamous cell carcinoma by an oncolytic herpes simplex virus. | Journal of the American College of Surgeons | J Am Coll Surg | 193 | 1 | 10.1016/s1072-7515(01)00866-3 | eng | 2,001 | 7 | null | null | null | null | [BACKGROUND] The prognosis of patients with advanced or recurrent head and neck squamous cell carcinoma remains poor despite refinements in multimodality therapies. This study evaluates the efficacy of a replication-competent, attenuated, oncolytic herpes simplex virus, NV1020, as a novel agent in the treatment of huma... | null | 1.457 | 212 | Surgery | Medicine | 2,001 |
11,441,745 | Tobacco, betel quid, alcohol, and illicit drug use among 13- to 35-year-olds in I-Lan, rural Taiwan: prevalence and risk factors. | American journal of public health | Am J Public Health | 91 | 7 | 10.2105/ajph.91.7.1130 | eng | 2,001 | 7 | null | null | null | null | [OBJECTIVES] This study determined the prevalence of and risk factors for substance use among rural Taiwanese. [METHODS] We used a survey of a representative sample of 6318 participants aged 13 to 35 years in I-Lan, Taiwan, in 1996 through 1997. [RESULTS] Perceived use of illicit drugs by peers, tobacco smoking, betel ... | null | 1.988 | 321 | Public Health, Environmental and Occupational Health | Medicine | 2,001 |
11,441,201 | Enhanced endothelium-dependent vasodilation in Fabry disease. | Stroke | Stroke | 32 | 7 | 10.1161/01.str.32.7.1559 | eng | 2,001 | 7 | null | null | null | null | [BACKGROUND AND PURPOSE] Fabry disease is an X-linked lysosomal storage disease secondary to deficiency of alpha-galactosidase A with resulting glycolipid accumulation, particularly globotriaosylceramide in arterial smooth muscle and endothelial cells. A systemic vasculopathy, including early-onset stroke, is prevalent... | null | 3.022 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,001 |
11,440,827 | Reduced sensitivity of inducible nitric oxide synthase-deficient mice to chronic colitis. | Free radical biology & medicine | Free Radic Biol Med | 31 | 2 | 10.1016/s0891-5849(01)00565-2 | eng | 2,001 | 7 | 15 | null | null | null | [BACKGROUND] Overproduction of nitric oxide by the inducible form of nitric oxide synthase (iNOS) has been implicated in colitis. Different authors have postulated both toxic and protective effects of nitric oxide (NO) in the pathophysiology of active inflammation. The objective of this study was to examine the role of... | null | null | null | null | null | null |
11,440,824 | Growth-restricted premature infants are at increased risk for low thyroxine. | Early human development | Early Hum Dev | 64 | 2 | 10.1016/s0378-3782(01)00172-4 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To evaluate, in extremely premature infants, the relationship between growth restriction and early total thyroxine levels, and to determine how maternal, prenatal, perinatal and neonatal variables influence the relationship. [STUDY DESIGN] 719 infants born at four medical centers in Massachusetts, New York ... | null | 0.553 | 115 | Pediatrics, Perinatology and Child Health; Obstetrics and Gynecology | Medicine | 2,001 |
11,440,787 | Clinical impact of histidine-ketoglutarate-tryptophan (HTK) cardioplegic solution on the perioperative period in open heart surgery patients. | Archives of medical research | Arch Med Res | 32 | 4 | 10.1016/s0188-4409(01)00296-x | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Ischemia-reperfusion injury during open heart surgery related to unsuccessful myocardial protection may increase morbidity or mortality. We analyze the clinical outcome after cardiac surgery with a cardioplegic solution based on intracellular components added with histidine-ketoglutarate-tryptophan. [METHO... | null | 0.227 | 100 | Medicine | Medicine | 2,001 |
11,440,411 | The research abstract: worth getting it right. | Irish journal of medical science | Ir J Med Sci | 170 | 1 | 10.1007/BF03167719 | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Scientific merit and clarity are critical in evaluation of quality in research. We hypothesised that avoidable errors of presentation adversely impact on abstract selection for scientific meetings. [AIM] To prospectively evaluate compliance with abstract guidelines among abstracts submitted to a national s... | null | 0.161 | 46 | Medicine | Medicine | 2,001 |
11,438,839 | Fatigue in polio survivors. | Spinal cord | Spinal Cord | 39 | 5 | 10.1038/sj.sc.3101147 | eng | 2,001 | 5 | null | null | null | null | [OBJECTIVES] Fatigue is commonly reported among polio survivors. The aims of the present study were to examine the incidence of perceived fatigue among a sample of Norwegian polio survivors, and to examine the association between the level of fatigue and sociodemographic and health variables. [MATERIALS AND METHODS] A ... | null | 0.806 | 131 | Medicine; Neurology; Neurology | Medicine; Neuroscience | 2,001 |
11,438,269 | Measuring medical students' experience with surgical problems and procedures. | American journal of surgery | Am J Surg | 181 | 4 | 10.1016/s0002-9610(01)00572-4 | eng | 2,001 | 4 | null | null | null | null | [BACKGROUND] Measuring medical students' experience on their surgical clerkship rotations to assess the adequacy of the breadth of exposure is essential for producing generalist clinicians. [METHODS] A Surgical Clinical Checklist was developed by surveying the surgical faculty for those surgical problems and procedures... | null | 1.205 | 173 | Medicine; Surgery | Medicine | 2,001 |
11,436,891 | Magnetic resonance imaging of the fetus in congenital intrathoracic disorders: preliminary observations. | Pediatric radiology | Pediatr Radiol | 31 | 6 | 10.1007/s002470100450 | eng | 2,001 | 6 | null | null | null | null | [BACKGROUND AND OBJECTIVE] Advances in magnetic resonance imaging (MRI) provide high-quality images of the intrathoracic organs. We studied the ability of MRI to define spatial relationships of the fetal lungs and measured lung volume in two cases of congenital diaphragmatic hernia (CDH), one of severe oligohydramnios ... | null | 0.514 | 104 | Pediatrics, Perinatology and Child Health; Radiology, Nuclear Medicine and Imaging | Medicine | 2,001 |
11,435,886 | Laparoscopic radiofrequency thermal ablation of renal tissue with and without hilar occlusion. | The Journal of urology | J Urol | 166 | 1 | null | eng | 2,001 | 7 | null | null | null | null | [PURPOSE] Few studies have evaluated the effect of radiofrequency thermal ablation on renal tissue, although it has been used clinically to treat small renal masses. We studied the size and histology of lesions created with radiofrequency thermal ablation administered via the laparoscopic approach with and without hila... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,435,820 | Extraperitoneal laparoscopic pyeloplasty: a multicenter study of 55 procedures. | The Journal of urology | J Urol | 166 | 1 | null | eng | 2,001 | 7 | null | null | null | null | [PURPOSE] We assessed the feasibility, reproducibility and morbidity of retroperitoneal laparoscopic pyeloplasty for ureteropelvic junction obstruction. [MATERIALS AND METHODS] A total of 55 retroperitoneal laparoscopic pyeloplasties were performed at 3 institutions between September 1996 and May 2000 in 33 women and 2... | null | 1.655 | 291 | Urology | Medicine | 2,001 |
11,435,735 | Total serum IgE levels in chronic hepatitis C: influence of interferon alpha therapy. | International archives of allergy and immunology | Int Arch Allergy Immunol | 125 | 2 | 10.1159/000053812 | eng | 2,001 | 6 | null | null | null | null | [BACKGROUND] Liver disease has been considered a prominent cause of IgE elevation. No data on serum IgE levels in chronic hepatitis C have been reported. Interferon-alpha is a standard therapy for chronic hepatitis C. Cytokine use is a promising type of immunomodulation in the treatment of IgE-mediated diseases. The ef... | null | 0.796 | 115 | Medicine; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,001 |
11,435,111 | Thioredoxin fold as homodimerization module in the putative chaperone ERp29: NMR structures of the domains and experimental model of the 51 kDa dimer. | Structure (London, England : 1993) | Structure | 9 | 6 | 10.1016/s0969-2126(01)00607-4 | eng | 2,001 | 6 | null | null | null | null | [BACKGROUND] ERp29 is a ubiquitously expressed rat endoplasmic reticulum (ER) protein conserved in mammalian species. Fold predictions suggest the presence of a thioredoxin-like domain homologous to the a domain of human protein disulfide isomerase (PDI) and a helical domain similar to the C-terminal domain of P5-like ... | null | null | null | null | null | null |
11,434,496 | Patient attitudes toward issues of environmental health. | Wilderness & environmental medicine | Wilderness Environ Med | 12 | 2 | 10.1580/1080-6032(2001)012[0086:patioe]2.0.co;2 | eng | 2,001 | null | null | null | null | null | [OBJECTIVE] Although the place of environmental health in medical education has been cautiously explored, patient attitudes toward environmental issues have been largely ignored in the medical literature. The purpose of this study was to evaluate the baseline level of family practice patient concerns about a variety of... | null | null | null | null | null | null |
11,433,880 | Lithium revisited: savings brought about by the use of lithium, 1970-1991. | The Psychiatric quarterly | Psychiatr Q | 72 | 2 | 10.1023/a:1010319610021 | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Recent estimates of the cost of manic-depressive illness totaled roughly $45 billion in 1991. Using data from the Epidemiological Catchment Area (ECA) study, this study estimates the savings brought about by the use of lithium between 1970 and 1991. [METHODS] Total savings are the difference between estima... | null | 0.737 | 67 | Psychiatry and Mental Health | Medicine | 2,001 |
11,433,823 | Mitral annular calcifications and aortic plaques as predictors of increased cardiovascular mortality. | Journal of cardiology | J Cardiol | 37 Suppl 1 | null | null | eng | 2,001 | null | null | null | null | null | [OBJECTIVES] Mitral annular calcifications (MAC) and aortic plaques are predictive for higher incidence of recurrent embolic events, the presence and severity of coronary artery disease and total cardiac deaths. However, no data exist comparing the impact of combined presence of both aortic plaques and MAC on embolic e... | null | 0.16 | 66 | Cardiology and Cardiovascular Medicine | Medicine | 2,001 |
11,433,091 | Neutrophil CD11b expression and circulating interleukin-8 as diagnostic markers for early-onset neonatal sepsis. | Pediatrics | Pediatrics | 108 | 1 | 10.1542/peds.108.1.e12 | eng | 2,001 | 7 | null | null | null | null | [OBJECTIVE] To assess neutrophil CD11b and circulating interleukin 8 (IL-8) as markers of early-onset infection in neonates. [METHODS] The study comprised 39 neonates, with a gestational age of 29 to 41 weeks, suspected of infection within 48 hours of life. Neutrophil surface expression of CD11b was quantified with flo... | null | 2.157 | 409 | Pediatrics, Perinatology and Child Health | Medicine | 2,001 |
11,432,696 | Low-dose citalopram as a 5-HT neuroendocrine probe. | Psychopharmacology | Psychopharmacology (Berl) | 155 | 3 | 10.1007/s002130100729 | eng | 2,001 | 5 | null | null | null | null | [RATIONALE] Intravenous administration of the selective serotonin re-uptake inhibitor, citalopram (20 mg), is known to increase plasma prolactin (PRL) and cortisol in human subjects. This suggests that citalopram may be a useful tool to probe brain serotonin function. [OBJECTIVE] To find out whether lower doses of intr... | null | 1.42 | 218 | Pharmacology | Pharmacology, Toxicology and Pharmaceutics | 2,001 |
11,432,508 | Prevalence of intestinal metaplasia in the distal oesophagus, oesophagogastric junction and gastric cardia in symptomatic patients in north-east Italy: a prospective, descriptive survey. The Italian Ulcer Study Group "GISU". | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver | Dig Liver Dis | 33 | 4 | 10.1016/s1590-8658(01)80084-0 | eng | 2,001 | 5 | null | null | null | null | [BACKGROUND] Incidence of adenocarcinoma of distal oesophagus and gastric cardia, probably arising from areas of intestinal metaplasia, has been increasing rapidly. [AIMS] To define prevalence of intestinal metaplasia of distal oesophagus, oesophagogastric junction and gastric cardia and to evaluate potential associate... | null | 0.433 | 113 | Gastroenterology; Hepatology | Medicine | 2,001 |
11,432,050 | Improvement in quality of life after bilateral transthoracic endoscopic sympathectomy for palmar hyperhydrosis. | Hawaii medical journal | Hawaii Med J | 60 | 5 | null | eng | 2,001 | 5 | null | null | null | null | [OBJECTIVE] To evaluate the efficacy of bilateral transthoracic endoscopic sympathectomy (TES), in alleviating symptoms and improving quality of life for patients in Hawaii. [DESIGN] Retrospective cohort study. [MATERIALS AND METHODS] Patients who had undergone TES were evaluated by phone interview and the SF-36 questi... | null | null | null | null | null | null |
11,432,004 | Surveys to assess the amount of pesticide in wool and the use of pesticides by woolgrowers in Queensland. | Australian veterinary journal | Aust Vet J | 79 | 5 | 10.1111/j.1751-0813.2001.tb12014.x | eng | 2,001 | 5 | null | null | null | null | [OBJECTIVE] To measure the amounts of pesticide residue in wool grown in Queensland between 1997 and 1999, and to describe the use of pesticides for the control of lice infestations and blowfly strike in Queensland sheep flocks. [DESIGN] Pesticide residues were measured in a random sample of wool from Queensland clips ... | null | 0.391 | 71 | Medicine; Veterinary | Medicine; Veterinary | 2,001 |
11,431,762 | Mechanisms for the development of esophageal atresia. | Journal of pediatric surgery | J Pediatr Surg | 36 | 7 | 10.1053/jpsu.2001.24722 | eng | 2,001 | 7 | null | null | null | null | [BACKGROUND] There is no universally accepted theory to explain esophageal embryology and the abnormal development that produces esophageal atresia. [METHODS] The impact of Adriamycin administration on the pathogenesis of esophageal atresia was studied in the rat model of VATER association, from embryonic day (ED) 10 t... | null | 0.804 | 147 | Medicine; Pediatrics, Perinatology and Child Health; Surgery | Medicine | 2,001 |
11,430,636 | Relative bioavailability of imipramine (Tofranil) coated tablets in healthy volunteers. | International journal of clinical pharmacology and therapeutics | Int J Clin Pharmacol Ther | 39 | 6 | null | eng | 2,001 | 6 | null | null | null | null | [OBJECTIVES] Imipramine is a tricyclic antidepressant drug with a considerable hepatic first-pass metabolism resulting in highly variable pharmacokinetic characteristics and desipramine as active major metabolite. This study describes the bioavailability of 3 formulations of imipramine. [METHODS] In a randomized, three... | null | null | null | null | null | null |
11,430,604 | Meanings of good nursing care among Thai female last-year undergraduate nursing students. | Journal of advanced nursing | J Adv Nurs | 34 | 1 | 10.1046/j.1365-2648.2001.3411738.x | eng | 2,001 | 4 | null | null | null | null | [AIMS OF THE STUDY] To describe and express the meanings of good nursing care among female last-year undergraduate nursing students of a nursing college in Bangkok, Thailand. [BACKGROUND] In Thailand today, nursing educational programmes aim at producing graduates who can explore options in nursing science. [METHOD] Tw... | null | 0.477 | 187 | Nursing | Nursing | 2,001 |
11,429,774 | Monitoring phytoplankton, bacterioplankton, and virioplankton in a coastal inlet (Bedford Basin) by flow cytometry. | Cytometry | Cytometry | 44 | 3 | 10.1002/1097-0320(20010701)44:3<236::aid-cyto1116>3.0.co;2-5 | eng | 2,001 | 7 | 1 | null | null | null | [BACKGROUND] To establish the prevailing state of the ecosystem for the assessment of long-term change, the abundance of microbial plankton in Bedford Basin (Nova Scotia, Canada) is monitored weekly by flow cytometry. [METHODS] Phytoplankton are detected by their chlorophyll autofluorescence. Those that contain phycoer... | null | null | null | null | null | null |
11,429,728 | Intraoral distraction osteogenesis of the mandible in hemifacial microsomia. | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons | J Oral Maxillofac Surg | 59 | 7 | 10.1053/joms.2001.24280 | eng | 2,001 | 7 | null | null | null | null | [PURPOSE] Lengthening of the mandible by distraction osteogenesis is the preferred method for treatment of hemifacial microsomia in children. Use of an intraoral distraction technique and horizontal oblique ramus osteotomy in such patients is presented. [PATIENTS AND METHODS] Mandibular ramus lengthening was performed ... | null | 0.607 | 147 | Otorhinolaryngology; Surgery; Oral Surgery | Dentistry; Medicine | 2,001 |
11,429,428 | Sentinel node investigation in breast cancer: detailed analysis of the yield from step sectioning and immunohistochemistry. | Journal of clinical pathology | J Clin Pathol | 54 | 7 | 10.1136/jcp.54.7.550 | eng | 2,001 | 7 | null | null | null | null | [AIMS] To evaluate in detail the extent to which step sectioning and immunohistochemical examination of sentinel lymph nodes (SNs) in patients with breast cancer reveal additional node positive patients, to arrive at a sensitive yet workable protocol for histopathological SN examination. [METHODS] This study comprised ... | null | 0.709 | 158 | Medicine; Pathology and Forensic Medicine | Medicine | 2,001 |
11,428,742 | Anisakis simplex-sensitized patients: should fish be excluded from their diet? | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology | Ann Allergy Asthma Immunol | 86 | 6 | 10.1016/S1081-1206(10)62298-3 | eng | 2,001 | 6 | null | null | null | null | [BACKGROUND] Anisakis simplex (A.s.) allergy is an emerging disease. The third-stage larvae of this nematode are a source of hidden allergens in fish. There are no clear guidelines concerning dietary restrictions for patients with serum-specific IgE to this parasite. [OBJECTIVE] To follow up the clinical data and immun... | null | null | null | null | null | null |
11,428,735 | Once-daily budesonide inhalation powder (Pulmicort Turbuhaler) maintains pulmonary function and symptoms of asthmatic children previously receiving inhaled corticosteroids. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology | Ann Allergy Asthma Immunol | 86 | 6 | 10.1016/S1081-1206(10)62291-0 | eng | 2,001 | 6 | null | null | null | null | [BACKGROUND] The incidence of pediatric asthma has increased dramatically over the past few decades, with approximately 5% of American children affected by the disease. [OBJECTIVES] To compare the efficacy and safety of once-daily budesonide Turbuhaler with placebo in asthmatic children previously treated with orally i... | null | null | null | null | null | null |
11,428,586 | Diagnostic value of serum markers of connective tissue turnover for predicting histological staging and grading in patients with chronic hepatitis C. | Journal of gastroenterology | J Gastroenterol | 36 | 6 | 10.1007/s005350170084 | eng | 2,001 | 6 | null | null | null | null | [PURPOSE] Chronic hepatitis C is an insidiously progressive disease, in which repeated assessment of liver histology is required. Various serum fibrotic markers have now been introduced. Our present aim was to assess, by receiver operating characteristic analysis, the usefulness of serum fibrotic markers for diagnosing... | null | 0.539 | 140 | Gastroenterology | Medicine | 2,001 |
11,427,455 | Pharmacokinetic basis for the efficient and safe use of low-dose mycophenolate mofetil in combination with tacrolimus in kidney transplantation. | Clinical chemistry | Clin Chem | 47 | 7 | null | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Mycophenolate mofetil (MMF) is an effective posttransplantation immunosuppressive agent used in combination with cyclosporin A (CsA) or tacrolimus (Tc). An increase in plasma mycophenolic acid (MPA) has been shown in patients receiving Tc-MMF combination therapy compared with CsA-MMF combination therapy at... | null | 1.238 | 248 | Biochemistry; Clinical Biochemistry | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,426,967 | Ten-year survival of patients with locally advanced, stage ib-iib cervical cancer after neoadjuvant chemotherapy and radical hysterectomy. | Gynecologic oncology | Gynecol Oncol | 82 | 1 | 10.1006/gyno.2001.6204 | eng | 2,001 | 7 | null | null | null | null | [OBJECTIVE(S)] The aim of this study was to evaluate the effects of neoadjuvant chemotherapy and radical hysterectomy on long-term survival in stage IB-IIB locally advanced cervical cancer by conducting a 10-year follow-up. [METHODS] Between August 1983 and May 1990, 80 locally advanced, stage IB-IIB cervical cancer pa... | null | 0.895 | 192 | Obstetrics and Gynecology; Oncology | Medicine | 2,001 |
11,426,516 | Antenatal depression, substance dependency and social support. | Journal of affective disorders | J Affect Disord | 65 | 1 | 10.1016/s0165-0327(00)00265-2 | eng | 2,001 | 6 | null | null | null | null | [BACKGROUND] The purpose of this study was to explore the prevalence of depression and factors associated with depressive mood among pregnant women. [METHOD] 391 women who were 14-37 weeks pregnant were evaluated with the Edinburgh Postnatal Depression Screen (EPDS), which has also been validated for prenatal use. Four... | null | 1.347 | 245 | Clinical Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,001 |
11,426,363 | Comparison of the effects of a cell saver and low-dose aprotinin on blood loss and homologous blood usage in patients undergoing valve surgery. | Journal of cardiothoracic and vascular anesthesia | J Cardiothorac Vasc Anesth | 15 | 3 | 10.1053/jcan.2001.23282 | eng | 2,001 | 6 | null | null | null | null | [OBJECTIVE] To compare 2 important techniques of blood conservation, use of a cell saver and low-dose aprotinin, in terms of blood loss and homologous blood usage in patients undergoing cardiac valve surgery. [DESIGN] Prospective, randomized. [SETTING] Tertiary care hospital. [PARTICIPANTS] Sixty adult patients undergo... | null | 0.488 | 100 | Anesthesiology and Pain Medicine; Cardiology and Cardiovascular Medicine | Medicine | 2,001 |
11,426,155 | Effect of age on outcomes of tertiary rehabilitation for chronic disabling spinal disorders. | Spine | Spine (Phila Pa 1976) | 26 | 12 | 10.1097/00007632-200106150-00023 | eng | 2,001 | 6 | 15 | null | null | null | [STUDY DESIGN] A prospective cohort study evaluating age as a factor in treatment outcomes for chronic disabling work-related spinal disorders undergoing tertiary rehabilitation. [OBJECTIVE] To assess the association between age and objective psychosocioeconomic treatment outcomes for work-related spinal disorders unde... | null | 1.078 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,001 |
11,426,145 | In vitro genesis of subaxial cervical unilateral facet dislocations through sequential soft tissue ablation. | Spine | Spine (Phila Pa 1976) | 26 | 12 | 10.1097/00007632-200106150-00009 | eng | 2,001 | 6 | 15 | null | null | null | [STUDY DESIGN] In vitro anatomic study investigating the degree of soft tissue disruption required to produce a subaxial cervical unilateral facet dislocation. [OBJECTIVES] To develop an understanding of the relative contributions to stability of the subaxial cervical soft tissues and to define an anatomic threshold of... | null | 1.078 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,001 |
11,425,994 | Lingual vascular canals of the mandible: evaluation with dental CT. | Radiology | Radiology | 220 | 1 | 10.1148/radiology.220.1.r01jl05186 | eng | 2,001 | 7 | null | null | null | null | [PURPOSE] To evaluate whether dental computed tomography (CT) can depict the frequency, diameter, position, and direction of vessels entering the mandible through lingual bone canals. [MATERIALS AND METHODS] Thirty-two consecutive patients underwent preimplantation CT of the lower jaw and examination for the presence, ... | null | 2.485 | 346 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,001 |
11,545,637 | Validation of a diagnostic multiplex polymerase chain reaction assay for infectious posterior uveitis. | Archives of ophthalmology (Chicago, Ill. : 1960) | Arch Ophthalmol | 119 | 9 | 10.1001/archopht.119.9.1315 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To validate a multiplex polymerase chain reaction (PCR) assay capable of simultaneously screening vitreous biopsy specimens for a panel of common pathogens in posterior uveitis. [METHODS] A multiplex PCR assay using novel primer sets for cytomegalovirus (CMV), herpes simplex virus (HSV), varicella zoster vi... | null | null | null | null | null | null |
11,525,700 | Unsaid but not forgotten: patients' unvoiced desires in office visits. | Archives of internal medicine | Arch Intern Med | 161 | 16 | 10.1001/archinte.161.16.1977 | eng | 2,001 | 9 | 10 | null | null | null | [OBJECTIVES] To examine patient, physician, and health care system characteristics associated with unvoiced desires for action, as well as the consequences of these unspoken requests. [PATIENTS AND METHODS] Patient surveys were administered before, immediately after, and 2 weeks after outpatient visits in the practices... | null | null | null | null | null | null |
11,546,880 | Site-specific atherosclerotic plaques in the carotid arteries of middle-aged women from southern Italy: associations with traditional risk factors and oxidation markers. | Stroke | Stroke | 32 | 9 | 10.1161/hs0901.095601 | eng | 2,001 | 9 | null | null | null | null | [BACKGROUND AND PURPOSE] Studies on cardiovascular disease have preferentially involved men because of the lower frequency of the disease in preelderly women. The aim of this analysis was to examine, with the use of a standardized ultrasound protocol, a cohort of women to differentiate early atherosclerotic lesions in ... | null | 3.022 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,001 |
11,545,675 | Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder. | BMC neuroscience | BMC Neurosci | 2 | null | 10.1186/1471-2202-2-10 | eng | 2,001 | null | null | 2,001 | 8 | 15 | [BACKGROUND] Alterations in arginine vasopressin regulation and secretion have been proposed as one possible biochemical abnormality in patients with obsessive-compulsive disorder. In golden hamsters, arginine vasopressin microinjections into the anterior hypothalamus trigger robust grooming and flank marking, a stereo... | null | 0.121 | 116 | Cellular and Molecular Neuroscience; Neuroscience | Neuroscience | 2,001 |
11,544,902 | Applications of two-step intensity modulated arc therapy. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] | Strahlenther Onkol | 177 | 8 | 10.1007/pl00002421 | eng | 2,001 | 8 | null | null | null | null | [PURPOSE] Organs at risk sometimes are surrounded by the target volume. At a first glance it seems to be impossible, to spare the organs at risk, i.e. the spinal cord, without underdosage of parts of the concave target volume. A fast method called "two-step intensity modulated arc therapy" (two-step IMAT) will be shown... | null | 0.636 | 81 | Oncology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,001 |
11,543,750 | Polycystic ovarian syndrome (PCOS) and insulin resistance. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics | Int J Gynaecol Obstet | 74 | 3 | 10.1016/s0020-7292(01)00442-8 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVES] Polycystic ovary syndrome (PCOS) presents a high risk of developing type 2 diabetes mellitus. We studied a group of women with PCOS and evaluated this defect in insulin action. [METHODS] The study population consisted of nine PCOS women, six obese type 2 diabetic patients, and five controls whose body mass... | null | null | null | null | null | null |
11,536,421 | Quality of life in patients attending a low-risk gynaecological oncology follow-up clinic. | Psycho-oncology | Psychooncology | 10 | 5 | 10.1002/pon.539 | eng | 2,001 | null | null | null | null | null | [OBJECTIVES] (1) To assess the quality of life (QOL) of patients who had been treated for gynaecological malignancies and who were attending a low risk follow-up clinic. (2) To determine the accuracy of the clinic physicians' assessment of patients' QOL compared with the Functional Living Index-Cancer (FLI-C) [Schipper... | null | 1.048 | 165 | Oncology; Psychiatry and Mental Health; Experimental and Cognitive Psychology | Medicine; Psychology | 2,001 |
11,535,933 | Analysis of the expression of estrogen and progesteron receptors, and of PCNA and Ki67 proliferation antigens, in uterine myomata cells in relation to the phase of the menstrual cycle. | Medical science monitor : international medical journal of experimental and clinical research | Med Sci Monit | 7 | 5 | null | eng | 2,001 | null | null | null | null | null | [BACKGROUND] The purpose of this study was to provide an immunocytochemical evaluation of the expression of receptors for estrogens (ER) and progesterone (PgR), and of Ki67 and PCNA (proliferating cell nuclear antigen) proliferation antigens in uterine myomata cells in three groups of patients operated in various phase... | null | 0.113 | 107 | Medicine | Medicine | 2,001 |
11,535,925 | Alteration of DNA base excision repair enzymes hMYH and hOGG1 in hydrogen peroxide resistant transformed human breast cells. | Medical science monitor : international medical journal of experimental and clinical research | Med Sci Monit | 7 | 5 | null | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Oxidative stress is a major causative agent of carcinogenesis, aging, and a number of diseases. 8-oxoG is the most stable and deleterious lesion of oxidative DNA damage. The 8-oxoG lesions can be eliminated by human repair systems consisting of three enzymes hMTH1, hOGG1, and hMYH homologous to E. coli Mut... | null | 0.113 | 107 | Medicine | Medicine | 2,001 |
11,535,706 | Use of the probasin promoter ARR2PB to express Bax in androgen receptor-positive prostate cancer cells. | Journal of the National Cancer Institute | J Natl Cancer Inst | 93 | 17 | 10.1093/jnci/93.17.1314 | eng | 2,001 | 9 | 5 | null | null | null | [BACKGROUND] Adenovirus-mediated overexpression of the apoptosis-inducing protein Bax can induce apoptosis in prostate cancer cell lines. Constitutive overexpression of Bax could result in unwanted apoptosis in every site of accidental Bax accumulation in vivo. Therefore, we developed an adenoviral construct (Av-ARR2PB... | null | 3.925 | 394 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
11,533,753 | X-linked adrenoleukodystrophy. The Saudi experience. | Saudi medical journal | Saudi Med J | 21 | 1 | null | eng | 2,000 | 1 | null | null | null | null | [OBJECTIVES] To evaluate the clinical, biochemical, neuroradiological, and neurophysiological findings of patients with X-linked adrenoleukodystrophy. [METHODS] Retrospective study evaluating the data of 10 X-linked adrenoleukodystrophy patients diagnosed at King Faisal Specialist Hospital and Research Centre, Riyadh, ... | null | null | null | null | null | null |
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