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11,532,482
Peritoneal mesothelial hypoxia during pneumoperitoneum is a cofactor in adhesion formation in a laparoscopic mouse model.
Fertility and sterility
Fertil Steril
76
3
10.1016/s0015-0282(01)01964-1
eng
2,001
9
null
null
null
null
[OBJECTIVE] To develop a laparoscopic mouse model to evaluate the hypothesis that mesothelial hypoxia during pneumoperitoneum is a cofactor in adhesion formation. [DESIGN] Prospective randomized trials. [SETTING] Academic research center. [ANIMAL(S)] One hundred thirty female Naval Medical Research Institute (NMRI) mic...
null
1.354
252
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,001
11,532,412
Discussion of death and dying in surgical textbooks.
American journal of surgery
Am J Surg
182
1
10.1016/s0002-9610(01)00646-8
eng
2,001
7
null
null
null
null
[BACKGROUND] Quality end-of-life care is an increasing concern for the public and the medical profession. Surgical textbooks could serve as an important educational and reference resource to improve this care. [METHODS] Four general surgical textbooks were scored for helpful information on death and dying for eight sur...
null
1.205
173
Medicine; Surgery
Medicine
2,001
11,532,326
Self-treatment of hypoglycemia while driving.
Diabetes research and clinical practice
Diabetes Res Clin Pract
54
1
10.1016/s0168-8227(01)00274-1
eng
2,001
10
null
null
null
null
[OBJECTIVE] While it is clear that progressive diabetic hypoglycemia leads to neuroglycopenia, which impairs driving, it is not clear what contributes to patients' detection and subsequent self-correction of hypoglycemia/driving impairments. Drivers with Type 1 Diabetes Mellitus (T1DM) who did and did not engage in sel...
null
0.674
146
Internal Medicine; Medicine; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,532,200
An assessment of the usefulness of a rapid immuno-chromatographic test, "Determine trade mark malaria pf" in evaluation of intervention measures in forest villages of central India.
BMC infectious diseases
BMC Infect Dis
1
null
10.1186/1471-2334-1-10
eng
2,001
null
null
2,001
8
14
[BACKGROUND] Plasmodium falciparum malaria, is a major health problem in forested tribal belt of central India. Rapid and accurate methods are needed for the diagnosis of P. falciparum. We performed a blinded evaluation of the recently introduced Determine trade mark malaria pf test (Abbott, Laboratories, Japan) compar...
null
null
137
Infectious Diseases
Medicine
2,001
11,531,785
Effects of solar-simulated radiation dose fractionation on CD1a+ Langerhans cells and CD11b+ macrophages in human skin.
The British journal of dermatology
Br J Dermatol
145
2
10.1046/j.1365-2133.2001.04340.x
eng
2,001
8
null
null
null
null
[BACKGROUND] There are few human studies investigating the immunosuppressive effects of exposure to solar-simulated radiation (SSR) and its relationship with sunburn/erythema, and few comparative data on the importance of SSR exposure regimens. [OBJECTIVES] To evaluate whether SSR-induced erythema is a reliable end-poi...
null
1.142
214
Dermatology; Medicine
Medicine
2,001
11,531,618
Clinical and pregnancy outcome following ectopic pregnancy; a prospective study comparing expectancy, surgery and systemic methotrexate treatment.
Acta obstetricia et gynecologica Scandinavica
Acta Obstet Gynecol Scand
80
8
10.1034/j.1600-0412.2001.080008744.x
eng
2,001
8
null
null
null
null
[BACKGROUND] The improved possibility of an early diagnosis of ectopic pregnancy by use of serial quantitative beta-subunit human chorionic gonadotropin hormone levels together with transvaginal ultrasound has opened up options for conservative treatment. Systemic methotrexate treatment of unruptured ectopic pregnancy ...
null
0.628
126
Medicine; Obstetrics and Gynecology
Medicine
2,001
11,531,292
High sensitivity of PCR in situ hybridization for the detection of human papillomavirus infection in uterine cervical neoplasias.
Gynecologic oncology
Gynecol Oncol
82
2
10.1006/gyno.2001.6261
eng
2,001
8
null
null
null
null
[OBJECTIVE] This study was designed in order to examine whether the sensitivity of PCR in situ hybridization (PISH) is superior to that of fluorescence in situ hybridization (FISH) and immunocytochemical staining (ICS) in detecting the presence of human papillomavirus (HPV) infection in uterine cervical neoplasias. [ME...
null
0.895
192
Obstetrics and Gynecology; Oncology
Medicine
2,001
11,530,118
Sleep quality, estradiol levels, and behavioral factors in late reproductive age women.
Obstetrics and gynecology
Obstet Gynecol
98
3
10.1016/s0029-7844(01)01485-5
eng
2,001
9
null
null
null
null
[OBJECTIVE] To estimate the prevalence of perceived poor sleep in women aged 35-49 years and to correlate sleep quality with levels of gonadal steroids and predictors of poor sleep. [METHODS] A cohort of 218 black and 218 white women aged 35-47 years at enrollment (aged 37-49 at final follow-up) with regular menstrual ...
null
1.316
268
Obstetrics and Gynecology
Medicine
2,001
11,530,068
Intraocular injection of crystalline cortisone as adjunctive treatment of diabetic macular edema.
American journal of ophthalmology
Am J Ophthalmol
132
3
10.1016/s0002-9394(01)01010-8
eng
2,001
9
null
null
null
null
[PURPOSE] To report the clinical outcome of a diabetic patient with macular edema treated with an intravitreal injection of crystalline cortisone. [METHODS] Interventional case report. A 73-year-old patient with diabetes mellitus presented with clinically significant diffuse macular edema caused by nonproliferative dia...
null
1.651
221
Ophthalmology
Medicine
2,001
11,530,063
Pseudohypopyon of orange pigment overlying a stable choroidal nevus.
American journal of ophthalmology
Am J Ophthalmol
132
3
10.1016/s0002-9394(01)00992-8
eng
2,001
9
null
null
null
null
[PURPOSE] To report an unusual case of orange pigment pseudohypopyon overlying a choroidal nevus. [METHODS] Observational case report. A 45-year-old man presented with best-corrected visual acuity of 20/25 and metamorphopsia in the right eye secondary to localized subfoveal fluid. The detachment displayed a peculiar ap...
null
1.651
221
Ophthalmology
Medicine
2,001
11,529,664
EBV replicon vector system enhances transgene expression in vivo: applications to cancer gene therapy.
The journal of gene medicine
J Gene Med
3
4
10.1002/jgm.199
eng
2,001
null
null
null
null
null
[BACKGROUND] A major limitation of current cancer gene therapies is low and transient expression of the therapeutic gene. For long-term expression of transgenes in vivo, an Epstein-Barr virus (EBV) replicon vector has been developed. The present study examines the effect of the EBV replicon vector system and its applic...
null
1.192
102
Drug Discovery; Genetics; Genetics; Molecular Biology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,001
11,528,348
Maximal strength and power, endurance performance, and serum hormones in middle-aged and elderly men.
Medicine and science in sports and exercise
Med Sci Sports Exerc
33
9
10.1097/00005768-200109000-00022
eng
2,001
9
null
null
null
null
[PURPOSE] To examine maximal strength, power and muscle cross-sectional area, maximal and submaximal cycling endurance characteristics, and serum hormone concentrations of testosterone (T), free testosterone (FT), and cortisol (C) in middle-aged and elderly men. [METHODS] Maximal knee extension force (isometric; MIF(KE...
null
1.285
271
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,001
11,528,344
Relation between intensity of physical activity and breast cancer risk reduction.
Medicine and science in sports and exercise
Med Sci Sports Exerc
33
9
10.1097/00005768-200109000-00018
eng
2,001
9
null
null
null
null
[PURPOSE] To examine the influence of frequency, duration, and intensity of physical activity on risk of breast cancer and to compare breast cancer risks associated with self-reported versus assigned intensity levels of activity. [METHODS] A population-based case-control study of 1233 incident breast cancer cases and 1...
null
1.285
271
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,001
11,528,186
Radiation-induced haemorrhagic cystitis.
European urology
Eur Urol
40
2
10.1159/000049760
eng
2,001
8
null
null
null
null
[OBJECTIVES] In this article we review the literature concerning the frequency and management of severe haemorrhagic radiation-induced cystitis. [METHODS] A Medline search was performed from 1966 to 1999 for articles in English. A total of 309 references were found. Abstracts and complete articles were reviewed. [RESUL...
null
1.106
274
Urology
Medicine
2,001
11,528,136
Immunocytochemical detection of tumour cells in the thoracic duct of patients with an adenocarcinoma of the oesophagus.
Digestive surgery
Dig Surg
18
4
10.1159/000050152
eng
2,001
null
null
null
null
null
[BACKGROUND] Compared to other hollow viscus organs, the oesophagus has a unique anatomy in which lymphatic channels are abundantly present in the mucosa and submucosa. It has been hypothesized that tumour cells can directly disseminate from these superficial layers into the thoracic duct without passing juxta-tumoral ...
null
0.582
80
Gastroenterology; Surgery
Medicine
2,001
11,527,774
The smoke you don't see: uncovering tobacco industry scientific strategies aimed against environmental tobacco smoke policies.
American journal of public health
Am J Public Health
91
9
10.2105/ajph.91.9.1419
eng
2,001
9
null
null
null
null
[OBJECTIVES] This review details the tobacco industry's scientific campaign aimed against policies addressing environmental tobacco smoke (ETS) and efforts to undermine US regulatory agencies from approximately 1988 to 1993. [METHODS] The public availability of more than 40 million internal, once-secret tobacco company...
null
1.988
321
Public Health, Environmental and Occupational Health
Medicine
2,001
11,527,677
Parenteral nutrition support after bone marrow transplantation: comparison of total and partial parenteral nutrition during the early posttransplantation period.
Nutrition (Burbank, Los Angeles County, Calif.)
Nutrition
17
9
10.1016/s0899-9007(01)00628-1
eng
2,001
9
null
null
null
null
[OBJECTIVE] Bone marrow transplantation (BMT) usually is indicated if the patient's malignant disease involves the marrow or if hazard to the normal marrow is the limiting factor in the aggressive treatment of disease. The success of BMT depends on a complete team with all the resources needed to ensure optimal results...
null
0.486
168
Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Medicine; Nursing
2,001
11,527,657
Heritability of diurnal changes in food intake in free-living humans.
Nutrition (Burbank, Los Angeles County, Calif.)
Nutrition
17
9
10.1016/s0899-9007(01)00611-6
eng
2,001
9
null
null
null
null
[OBJECTIVES] The time of day of meal ingestion, the number of people present at the meal, the subjective state of hunger, and the estimated before-meal contents in the stomach have been established as influences on the amount eaten in a meal, and this influence has been shown to be heritable. Because these factors inte...
null
0.486
168
Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Medicine; Nursing
2,001
11,527,649
Effects of chronic atrial fibrillation on gap junction distribution in human and rat atria.
Journal of the American College of Cardiology
J Am Coll Cardiol
38
3
10.1016/s0735-1097(01)01443-7
eng
2,001
9
null
null
null
null
[OBJECTIVES] To elucidate the structural basis for the electrophysiologic remodeling induced by chronic atrial fibrillation (AF), we investigated connexin40 and connexin43 (Cx40 and Cx43) expression and distribution in atria of patients with and without chronic AF and in an animal model of AF with additional electrophy...
null
4.039
512
Cardiology and Cardiovascular Medicine
Medicine
2,001
11,527,635
The relationship between obesity and mortality in patients with heart failure.
Journal of the American College of Cardiology
J Am Coll Cardiol
38
3
10.1016/s0735-1097(01)01448-6
eng
2,001
9
null
null
null
null
[OBJECTIVES] The study aimed to evaluate the role of obesity in the prognosis of patients with heart failure (HF). [BACKGROUND] Previous reports link obesity to the development of HF. However, the impact of obesity in patients with established HF has not been studied. [METHODS] We analyzed 1,203 patients with advanced ...
null
4.039
512
Cardiology and Cardiovascular Medicine
Medicine
2,001
11,527,482
Disability in the oldest old: "can do" or "do do"?
Journal of the American Geriatrics Society
J Am Geriatr Soc
49
7
10.1046/j.1532-5415.2001.49181.x
eng
2,001
7
null
null
null
null
[OBJECTIVE] To investigate the discrepancies between outcomes for competence (can do) and actual performance (do do) in activities of daily living (ADLs). [DESIGN] Baseline measurements of a population-based follow-up study. [SETTING] Leiden 85-Plus Study, the Netherlands. [PARTICIPANTS] Five hundred and ninety-nine pe...
null
1.553
273
Geriatrics and Gerontology
Medicine
2,001
11,526,918
The putative collagen binding peptide hastens periodontal ligament cell attachment to bone replacement graft materials.
Journal of periodontology
J Periodontol
72
8
10.1902/jop.2001.72.8.990
eng
2,001
8
null
null
null
null
[BACKGROUND] Bone replacement graft (BRG) materials are often used to treat periodontal defects, to promote cellular invasion, and to encourage bone regrowth. Periodontal ligament fibroblasts (PDLF) incorporate these materials and form the basis of the renewed connection between the existing and newly formed alveolar b...
null
0.998
186
Periodontics
Dentistry
2,001
11,526,811
Pre-, peri-, and postnatal trauma in subjects with attention-deficit hyperactivity disorder.
Canadian journal of psychiatry. Revue canadienne de psychiatrie
Can J Psychiatry
46
6
10.1177/070674370104600609
eng
2,001
8
null
null
null
null
[OBJECTIVE] To review research on pre-, peri-, and postnatal stress and their potential relation to attention-deficit hyperactivity disorder (ADHD). [METHOD] We selected and critically reviewed 51 research reports from the medical and psychology literature, between January 1, 1976 and May 1, 2001, based on the subjects...
null
null
null
null
null
null
11,509,058
Cost-effectiveness of vitamin therapy to lower plasma homocysteine levels for the prevention of coronary heart disease: effect of grain fortification and beyond.
JAMA
JAMA
286
8
10.1001/jama.286.8.936
eng
null
null
null
null
null
null
[CONTEXT] A high homocysteine level has been identified as an independent modifiable risk factor for coronary heart disease (CHD) events and death. Since January 1998, the US Food and Drug Administration has required that all enriched grain products contain 140 microg of folic acid per 100 g, a level considered to decr...
null
null
null
null
null
null
11,525,547
A weighted version of the Melbourne Low-Vision ADL Index: a measure of disability impact.
Optometry and vision science : official publication of the American Academy of Optometry
Optom Vis Sci
78
8
10.1097/00006324-200108000-00008
eng
2,001
8
null
null
null
null
[OBJECTIVE] To develop a version of the Melbourne Low-Vision ADL Index that measures the personal impact of disability in activities of daily living (ADL's). Also, to determine the relationship between clinical measures of vision impairment and disability impact. [METHODS] The Melbourne Low-Vision ADL Index (MLVAI) is ...
null
0.351
121
Optometry; Ophthalmology
Health Professions; Medicine
2,001
11,525,442
Failure of resin ionomers in the retention of multi-rooted teeth with Class III furcation involvement: a rebuttal case report.
Journal of periodontology
J Periodontol
72
8
10.1902/jop.2001.72.8.1084
eng
2,001
8
null
null
null
null
[BACKGROUND] Severe periodontal furcation invasion has long been a treatment dilemma for the clinician. Many techniques have been advocated in the treatment of multi-rooted posterior teeth ranging from conventional scaling and root planing (SRP), apically positioned flaps, root amputations, root resections, tunnel proc...
null
0.998
186
Periodontics
Dentistry
2,001
11,525,437
Nitric oxide synthase activity in neutrophils from patients with localized aggressive periodontitis.
Journal of periodontology
J Periodontol
72
8
10.1902/jop.2001.72.8.1052
eng
2,001
8
null
null
null
null
[BACKGROUND] Localized aggressive periodontitis (LAgP) is associated with neutrophil dysfunction including defective chemotaxis and reduced calcium influx factor activity. Nitric oxide (NO) and its enzyme, nitric oxide synthase (NOS), have been suggested to be involved in chemotaxis. Some reports, however, were unable ...
null
0.998
186
Periodontics
Dentistry
2,001
11,525,230
A laboratory investigation of the role of guide planes in the retention of cast cobalt-chromium alloy partial denture frameworks.
Journal of dentistry
J Dent
29
4
10.1016/s0300-5712(01)00016-1
eng
2,001
5
null
null
null
null
[OBJECTIVES] This in vitro study examined the resistance to displacement offered by guide planes and the displacement mechanics of a bilateral bounded saddle cast cobalt chrome alloy removable partial denture framework under conditions simulating an average initial fit. [METHODS] A specially designed model mouth jig fi...
null
0.892
146
Dentistry
Dentistry
2,001
11,493,127
Dietary patterns and the risk of coronary heart disease in women.
Archives of internal medicine
Arch Intern Med
161
15
10.1001/archinte.161.15.1857
eng
null
null
null
null
null
null
[BACKGROUND] Although substantial information on individual nutrients or foods and risk of coronary heart disease (CHD) is available, little is known about the role of overall eating pattern. [METHODS] Using dietary information from a food frequency questionnaire in 1984 from the Nurses' Health Study, we conducted fact...
null
null
null
null
null
null
11,524,475
Clinical markers of early disease in persons near onset of Huntington's disease.
Neurology
Neurology
57
4
10.1212/wnl.57.4.658
eng
2,001
8
28
null
null
null
[OBJECTIVE] There is increasing evidence that neuron loss precedes the phenotypic expression of Huntington's disease (HD). As genes for late-onset neurodegenerative diseases are identified, the need for accurate assessment of phenoconversion (i.e., the transition from health to the disease phenotype) will be important....
null
2.19
422
Neurology
Medicine
2,001
11,524,202
Valacyclovir inhibition of recovery of ocular herpes simplex virus type 1 after experimental reactivation by laser in situ keratomileusis.
Journal of cataract and refractive surgery
J Cataract Refract Surg
27
8
10.1016/s0886-3350(01)00804-5
eng
2,001
8
null
null
null
null
[PURPOSE] To determine whether the systemic administration of valacyclovir (Valtrex) reduces ocular shedding of herpes simplex virus type 1 (HSV-1) after laser in situ keratomileusis (LASIK) in the New Zealand White (NZW) rabbit latency model. [SETTING] Department of Ophthalmology, University of Pittsburgh School of Me...
null
1.55
169
Ophthalmology; Sensory Systems; Surgery
Medicine; Neuroscience
2,001
11,524,200
200 Hz flying-spot technology of the LaserSight LSX excimer laser in the treatment of myopic astigmatism: six and 12 month outcomes of laser in situ keratomileusis and photorefractive keratectomy.
Journal of cataract and refractive surgery
J Cataract Refract Surg
27
8
10.1016/s0886-3350(01)00996-8
eng
2,001
8
null
null
null
null
[PURPOSE] To evaluate safety, efficacy, predictability, and stability in the treatment of myopic astigmatism with laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) using the 200 Hz flying-spot technology of the LaserSight LSX excimer laser. [SETTING] SynsLaser Clinic, Tromsø, Norway. [METHODS] ...
null
1.55
169
Ophthalmology; Sensory Systems; Surgery
Medicine; Neuroscience
2,001
11,523,966
Predicting outcomes of patients in Japan after first acute stroke using a simple model.
American journal of physical medicine & rehabilitation
Am J Phys Med Rehabil
80
9
10.1097/00002060-200109000-00003
eng
2,001
9
null
null
null
null
[OBJECTIVE] Prediction of patient outcome can be useful as an aid to clinical decision making. Many studies, including my own, have constructed predictive multivariate models for outcome following stroke rehabilitation therapy, but these have often required several minutes work with a pocket calculator. The aim is to d...
null
null
null
null
null
null
11,523,701
Early onset of lipid peroxidation after human traumatic brain injury: a fatal limitation for the free radical scavenger pharmacological therapy?
Journal of investigative medicine : the official publication of the American Federation for Clinical Research
J Investig Med
49
5
10.2310/6650.2001.33790
eng
2,001
9
null
null
null
null
[BACKGROUND] On the basis of the contradiction between data on experimental head trauma showing oxidative stress-mediated cerebral tissue damage and failure of the majority of clinical trials using free radical scavenger drugs, we monitored the time-course changes of malondialdehyde (MDA, an index of cell lipid peroxid...
null
null
null
null
null
null
11,523,673
A new mode of percutaneous upper thoracic phenol sympathicolysis: report of 50 cases.
Neurosurgery
Neurosurgery
49
3
10.1097/00006123-200109000-00017
eng
2,001
9
null
null
null
null
[OBJECTIVE] Our previous study demonstrated that a high concentration of phenol (75-90%) with minimal volume (0.02 ml) can elicit serious degeneration of ganglion cells of the stellate ganglia in cats. Another previous study in our clinical patients demonstrated that approximately 84 to 90% of the upper thoracic (T2-T3...
null
1.655
229
Neurology; Surgery
Medicine
2,001
11,522,866
Production of monokines in patients under polysulphone haemodiafiltration is influenced by the ultrafiltration flow rate.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Nephrol Dial Transplant
16
9
10.1093/ndt/16.9.1830
eng
2,001
9
null
null
null
null
[BACKGROUND] Chronic haemodialysis patients show various clinical signs of immunodeficiency and there is growing evidence that a dysregulated monocyte cytokine production is heavily involved in this deficiency. The production of monokines in vitro has been proposed to correlate closely with the in vivo immune status an...
null
0.742
203
Medicine; Nephrology; Transplantation
Medicine
2,001
11,522,748
Islet amyloid polypeptide is not a satisfactory marker for detecting pancreatic cancer.
Gastroenterology
Gastroenterology
121
3
10.1053/gast.2001.27210
eng
2,001
9
null
null
null
null
[BACKGROUND AND AIMS] Islet amyloid polypeptide (IAPP) levels are elevated in pancreatic cancer and may be a useful marker of pancreatic cancer-associated diabetes. The aim of this study was to compare the sensitivity and specificity for pancreatic cancer of IAPP with that of CA19-9, examine clinical characteristics of...
null
3.203
482
Gastroenterology
Medicine
2,001
11,522,553
Effects of a National Cholesterol Education Program Step II Diet on apolipoprotein A-IV metabolism within triacylglycerol-rich lipoproteins and plasma.
The American journal of clinical nutrition
Am J Clin Nutr
74
3
10.1093/ajcn/74.3.308
eng
2,001
9
null
null
null
null
[BACKGROUND] Apolipoprotein (apo) A-IV is a major component of triacylglycerol-rich lipoprotein (TRL) apolipoproteins. [OBJECTIVE] We investigated the effects of dietary saturated fat and cholesterol restriction on the metabolism of TRL and plasma apo A-IV. [DESIGN] We assessed TRL and plasma apo A-IV kinetics in 16 an...
null
2.283
390
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,001
11,522,271
Analytical evaluation of the Bio-Rad variant II automated HbA(1C) analyzer.
Clinical biochemistry
Clin Biochem
34
5
10.1016/s0009-9120(01)00229-6
eng
2,001
7
null
null
null
null
[OBJECTIVES] To evaluate the analytical performance of the Bio-Rad Variant II HbA(1C) analyzer (a completely automated system for the quantification of glycohemoglobin [HbA(1C)] in blood). [DESIGN AND METHODS] The analytical parameters of precision, linearity and analytical range were assessed and HbA(1C) results from ...
null
0.526
130
Medicine; Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,521,989
A prospective randomized controlled trial of intravenous ciprofloxacin as an adjunct to corticosteroids in acute, severe ulcerative colitis.
Scandinavian journal of gastroenterology
Scand J Gastroenterol
36
9
10.1080/003655201750305503
eng
2,001
9
null
null
null
null
[BACKGROUND] The role of antibiotics in the treatment of ulcerative colitis is controversial. This study aims at assessing the therapeutic role of ciprofloxacin as an adjunct to corticosteroids in acute severe ulcerative colitis. [METHODS] In this prospective, randomized, double-blind, placebo-controlled trial, 55 cons...
null
0.861
133
Gastroenterology
Medicine
2,001
11,521,785
A randomized trial of four cycles of adjuvant AC (adriamycin + cyclophosphamide) +/- two cycles of EP (etoposide + cisplatin) in node positive patients with breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology
Ann Oncol
12
7
10.1023/a:1011118004629
eng
2,001
7
null
null
null
null
[BACKGROUND] Four cycles of AC have been accepted as the standard chemotherapy in breast cancer. In the present randomized study we aimed to assess the efficacy of adjuvant etoposide + cisplatin (EP) combination following four cycles of standard adriamycin + cyclophosphamide (AC) in premenopausal patients with operable...
null
1.098
311
Hematology; Medicine; Oncology
Medicine
2,001
11,521,692
Alterations in expression of mucin, tenascin-c and syndecan-1 in the conjunctiva following retinal surgery and plaque radiotherapy.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Graefes Arch Clin Exp Ophthalmol
239
7
10.1007/s004170100301
eng
2,001
7
null
null
null
null
[PURPOSE] Disturbances of the ocular tear film layer and dry eye symptoms are common complications following retinal surgery and ocular tumour therapy. Examined were the histopathological changes of the conjunctiva following posterior segment surgery and plaque radiotherapy. [METHODS] Biopsy specimens of the superior b...
null
null
null
null
null
null
11,520,765
Effect of ABO blood group mismatching on corneal epithelial cells: an in vitro study.
The British journal of ophthalmology
Br J Ophthalmol
85
9
10.1136/bjo.85.9.1104
eng
2,001
9
null
null
null
null
[AIM] To determine, in vitro, the effects of blood group ABO mismatching on corneal epithelial cells. [METHODS] Corneal epithelial cell cultures were established from 32 human cadaver donor eyes. Epithelial cells (100 microl of 4 x 10(2) cells per microl) were incubated for 4 hours with antibodies against blood group a...
null
1.26
185
Ophthalmology; Sensory Systems; Cellular and Molecular Neuroscience
Medicine; Neuroscience
2,001
11,520,158
Microcystic adnexal carcinoma of the vulva.
Gynecologic oncology
Gynecol Oncol
82
3
10.1006/gyno.2001.6300
eng
2,001
9
null
null
null
null
[BACKGROUND] Microcystic adnexal carcinoma (MAC) is a subset of sweat gland carcinoma first described as a specific entity by D. J. Goldstein, R. J. Barr, and D. J. Santa Cruz (Cancer 1982;50:566-72). We report the first case of MAC occurring on the vulva and review the literature pertaining to this rare tumor. [CASE] ...
null
0.895
192
Obstetrics and Gynecology; Oncology
Medicine
2,001
11,519,844
Managed care, vertical integration strategies and hospital performance.
Health care management science
Health Care Manag Sci
4
3
10.1023/a:1011492731396
eng
2,001
9
null
null
null
null
[OBJECTIVE] The purpose of this study is to examine the association of managed care with hospital vertical integration strategies, as well as to observe the relationships of different types of vertical integration with hospital efficiency and financial performance. [DATA AND METHODS] The sample consists of 363 Californ...
null
null
null
null
null
null
11,519,769
A placebo-controlled comparison of the effects on sexual functioning of bupropion sustained release and fluoxetine.
Clinical therapeutics
Clin Ther
23
7
10.1016/s0149-2918(01)80090-4
eng
2,001
7
null
null
null
null
[BACKGROUND] Many antidepressants are associated with sexual dysfunction, a side effect that may lead to patients' dissatisfaction and noncompliance with treatment. [OBJECTIVE] This study compared the efficacy, tolerability, and effects on sexual functioning of bupropion sustained release (bupropion SR) and the selecti...
null
0.907
153
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,001
11,519,764
A prospective study on intake of animal products and risk of prostate cancer.
Cancer causes & control : CCC
Cancer Causes Control
12
6
10.1023/a:1011256201044
eng
2,001
8
null
null
null
null
[OBJECTIVE] Association between animal products and prostate cancer have been observed in numerous observational studies, but it is not clear whether the high fat content of these foods or some other component accounts for these associations. We examine these associations among 51,529 men who contributed detailed dieta...
null
null
null
null
null
null
11,518,843
Blood pressure, endothelial function and circulating endothelin concentrations in liver transplant recipients.
Journal of hypertension
J Hypertens
19
8
10.1097/00004872-200108000-00003
eng
2,001
8
null
null
null
null
[OBJECTIVES] To study candidates for liver transplant before and 6 weeks after transplant, and to elucidate the role of endothelial dysfunction and plasma endothelin concentrations in the development of hypertension. DESIGN PROSPECTIVE: follow-up study. [SETTING] Institutional, outpatient. [PATIENTS] and controls Fifte...
null
1.649
198
Cardiology and Cardiovascular Medicine; Internal Medicine; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,518,643
Clinical correlative evaluation of an iterative method for reconstruction of brain SPECT images.
Nuclear medicine and biology
Nucl Med Biol
28
6
10.1016/s0969-8051(01)00232-3
eng
2,001
8
null
null
null
null
[BACKGROUND] Brain SPECT and PET investigations have showed discrepancies in Alzheimer's disease (AD) when considering data deriving from deeply located structures, such as the mesial temporal lobe. These discrepancies could be due to a variety of factors, including substantial differences in gamma-cameras and underlyi...
null
0.749
100
Radiology, Nuclear Medicine and Imaging; Cancer Research; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,517,845
The process of clinical trials: a model for successful clinical trial participation.
Oncology nursing forum
Oncol Nurs Forum
28
7
null
eng
2,001
8
null
null
null
null
[PURPOSE/OBJECTIVES] To present barriers and strategies related to successful clinical trial participation and integrate them into a model for successful trial participation. [DATA SOURCES] The proposed model was developed based on a literature review related to clinical trial participation, review of empirical studies...
null
null
null
null
null
null
11,517,106
Long term complications of inferior vena cava thrombosis.
Archives of disease in childhood
Arch Dis Child
85
3
10.1136/adc.85.3.228
eng
2,001
9
null
null
null
null
[AIM] To evaluate the long term outcome after paediatric inferior vena cava (IVC) thrombosis. [METHODS] A combined retrospective and prospective study on infants and children with IVC thrombosis treated at Aachen and Maastricht University Hospitals between 1980 and 1999. [RESULTS] Forty patients were enrolled, includin...
null
0.931
169
Pediatrics, Perinatology and Child Health
Medicine
2,001
11,517,009
Circulating leptin concentrations and ovarian function in polycystic ovary syndrome.
European journal of endocrinology
Eur J Endocrinol
145
3
10.1530/eje.0.1450289
eng
2,001
9
null
null
null
null
[OBJECTIVE] Polycystic ovary syndrome (PCOS) is characterized by ovarian dysfunction. Although the role of leptin in the control of reproduction is unclear, it may be involved in the control of ovulation. The aim of this cross-sectional study was to determine the relationship between circulating leptin concentrations, ...
null
0.791
179
Medicine; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,516,029
Coronary stent implantation without lesion predilatation (direct stenting): our experience with this evolving technique.
Indian heart journal
Indian Heart J
53
3
null
eng
2,001
null
null
null
null
null
[BACKGROUND] Until recently, conventional intracoronary stent deployment required predilatation of the lesion with a balloon. However, "direct stenting" of the lesion without predilatation offers certain theoretical and practical advantages. We assessed the safety and feasibility of direct stenting in a select group of...
null
0.21
54
Cardiology and Cardiovascular Medicine
Medicine
2,001
11,515,884
Tranexamic acid in off-pump coronary surgery: a preliminary, randomized, double-blind, placebo-controlled study.
The Annals of thoracic surgery
Ann Thorac Surg
72
2
10.1016/s0003-4975(01)02802-8
eng
2,001
8
null
null
null
null
[BACKGROUND] We evaluated the hemostatic effects of tranexamic acid, a synthetic antifibrinolytic drug, in patients undergoing beating-heart coronary surgery. [METHODS] Forty consecutive patients were in a double-blind manner, prospectively randomized into two groups: 20 patients received tranexamic acid (bolus of 1 g ...
null
1.484
230
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,001
11,515,873
Surgical management of severe truncal insufficiency: experience with truncal valve remodeling techniques.
The Annals of thoracic surgery
Ann Thorac Surg
72
2
10.1016/s0003-4975(01)02785-0
eng
2,001
8
null
null
null
null
[BACKGROUND] Truncal valve insufficiency has been a significant short- and long-term risk factor for repair of truncus arteriosus. Recent reports have documented the virtues of truncal valve repair. The purpose of this report is to review our experience with truncal valve repair and illustrate our techniques. [METHODS]...
null
1.484
230
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,001
11,515,640
Dental erosion in children and adolescents--a cross-sectional and longitudinal investigation using study models.
Community dentistry and oral epidemiology
Community Dent Oral Epidemiol
29
4
10.1034/j.1600-0528.2001.290405.x
eng
2,001
8
null
null
null
null
[OBJECTIVE] To investigate the prevalence and incidence of dental erosion in children and adolescents. [METHODS] Lesions were registered for all tooth surfaces of primary and permanent teeth using pre-orthodontic study models. A total of 1,000 individuals (mean age 11.4+/-3.3 years) were included; 265 of them were foll...
null
0.894
118
Dentistry; Public Health, Environmental and Occupational Health
Dentistry; Medicine
2,001
11,514,809
A piezoelectric film-based intrasplint detection method for bruxism.
The Journal of prosthetic dentistry
J Prosthet Dent
86
2
10.1067/mpr.2001.115487
eng
2,001
8
null
null
null
null
[STATEMENT OF PROBLEM] An accurate, easy-to-use, long-term method other than EMG is needed to monitor bruxism. [PURPOSE] This article presents pilot data on the reproducibility, validity, and utility of an intrasplint piezoelectric film method. [MATERIAL AND METHODS] Simulated bruxism behaviors (steady-state and rhythm...
null
0.527
160
Medicine; Oral Surgery
Dentistry; Medicine
2,001
11,514,386
Methods for determining the refractory period and excitable gap during persistent atrial fibrillation in the goat.
Circulation
Circulation
104
8
10.1161/hc3401.093156
eng
2,001
8
21
null
null
null
[BACKGROUND] Recently, the temporal excitable gap during atrial fibrillation (AF) has been identified as a vulnerable parameter for cardioversion of AF. In this study, we evaluated 5 methods to measure the refractory period (RP(AF)) and the excitable period (EP(AF)) during persistent AF. [METHODS AND RESULTS] In 11 goa...
null
5.548
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,001
11,514,226
Ingenol esters induce apoptosis in Jurkat cells through an AP-1 and NF-kappaB independent pathway.
Chemistry & biology
Chem Biol
8
8
10.1016/s1074-5521(01)00048-5
eng
2,001
8
null
null
null
null
[BACKGROUND] Ingenol derivatives have received constant and multidisciplinary attention on account of their pleiotropic pattern of biological activity. This includes activation of protein kinase C (PKC), tumour-promotion, anticancer, and anti-HIV properties, and the possibility of dissecting co-cancerogenic and clinica...
null
null
null
null
null
null
11,513,760
Effects of decreasing the frequency of ventilator circuit changes to every 7 days on the rate of ventilator-associated pneumonia in a Beijing hospital.
Respiratory care
Respir Care
46
9
null
eng
2,001
9
null
null
null
null
[INTRODUCTION] We investigated whether decreasing ventilator circuit changes from every 2 days to every 7 days would impact ventilator-associated pneumonia rates at our institution. [METHODS] All mechanically ventilated patients at Peking Union Medical College Hospital were studied over a 21 month period. From March 19...
null
0.196
112
Critical Care and Intensive Care Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,001
11,513,184
Small intestinal motor patterns in critically ill patients after major abdominal surgery.
The American journal of gastroenterology
Am J Gastroenterol
96
8
10.1111/j.1572-0241.2001.03951.x
eng
2,001
8
null
null
null
null
[OBJECTIVES] In patients who have had major surgery or trauma, early enteral feeding is safer and more effective than parenteral or nasogastric feeding but is frequently associated with diarrhea. Limited recordings have shown that the patterning of duodenal interdigestive motor activity is frequently abnormal after sur...
null
1.215
296
Gastroenterology; Hepatology
Medicine
2,001
11,513,099
Route learning performance in Alzheimer disease patients.
Neuropsychiatry, neuropsychology, and behavioral neurology
Neuropsychiatry Neuropsychol Behav Neurol
14
3
null
eng
2,001
null
null
null
null
null
[OBJECTIVE] To examine performance on an objective measure of route learning in Alzheimer disease (AD) patients. [BACKGROUND] Topographic disorientation (TD) is a common problem among AD patients. The underlying cognitive deficits that contribute to TD in AD patients are not well understood. [METHOD] This study examine...
null
null
null
null
null
null
11,511,833
Balsam-related systemic contact dermatitis.
Journal of the American Academy of Dermatology
J Am Acad Dermatol
45
3
10.1067/mjd.2001.114738
eng
2,001
9
null
null
null
null
[BACKGROUND] Positive patch tests to balsam of Peru (BOP) or fragrance mix (FM) suggest the possibility of systemic contact dermatitis from balsam-related foods and spices. [OBJECTIVE] This was a retrospective study to determine whether avoidance of balsam-related foods results in an improvement of dermatitis in these ...
null
1.254
256
Dermatology
Medicine
2,001
11,511,744
Survey of solvent related chronic encephalopathy as an occupational disease in European countries.
Occupational and environmental medicine
Occup Environ Med
58
9
10.1136/oem.58.9.575
eng
2,001
9
null
null
null
null
[OBJECTIVES] To obtain information about solvent related chronic encephalopathy (SRCE) in the countries of the European Union (EU). [METHOD] A survey was conducted in 1998 and 1999 among medical experts, authorities for health and safety, and social security institutions. [RESULTS] SRCE is an acknowledged occupational ...
null
1.375
167
Public Health, Environmental and Occupational Health
Medicine
2,001
11,511,640
Psychosocial work characteristics and self rated health in four post-communist countries.
Journal of epidemiology and community health
J Epidemiol Community Health
55
9
10.1136/jech.55.9.624
eng
2,001
9
null
null
null
null
[STUDY OBJECTIVES] To examine whether psychosocial factors at work are related to self rated health in post-communist countries. [DESIGN AND SETTINGS] Random samples of men and women in five communities in four countries were sent a postal questionnaire (Poland, Czech Republic and Lithuania) or were invited to an inter...
null
1.168
199
Public Health, Environmental and Occupational Health; Epidemiology
Medicine
2,001
11,511,428
Abnormal contractile responses during dobutamine stress echocardiography in patients with idiopathic dilated cardiomyopathy.
European journal of heart failure
Eur J Heart Fail
3
4
10.1016/s1388-9842(01)00143-x
eng
2,001
8
null
null
null
null
[BACKGROUND] In chronic heart failure augmented wall stress leads to increased energy demand. Supply, however, may be reduced due to coronary vasoconstriction and endothelial dysfunction. This might lead to a mismatch between demand and supply. In the present study we further explored the effect of increased demand dur...
null
null
null
null
null
null
11,511,119
Positron emission tomography using(18)F-fluoro-deoxyglucose and euglycaemic hyperinsulinaemic glucose clamp: optimal criteria for the prediction of recovery of post-ischaemic left ventricular dysfunction. Results from the European Community Concerted Action Multicenter study on use of(18)F-fluoro-deoxyglucose Positron ...
European heart journal
Eur Heart J
22
18
10.1053/euhj.2000.2585
eng
2,001
9
null
null
null
null
[AIMS] To assess the accuracy of positron emission tomography to predict recovery of global cardiac function after revascularization in patients with coronary artery disease. [METHODS AND RESULTS] One hundred and seventy-eight patients (157 male, 58+/-10 years) with coronary artery disease and left ventricular dysfunct...
null
null
null
null
null
null
11,509,842
Relation between average alcohol consumption and disease: an overview.
European addiction research
Eur Addict Res
7
3
10.1159/000050729
eng
2,001
8
null
null
null
null
[OBJECTIVE] To conduct an overview of alcohol-related health consequences and to estimate relative risk for chronic consequences and attributable fractions for acute consequences. [METHODS] Identification of alcohol-related consequences was performed by means of reviewing and evaluating large-scale epidemiological stud...
null
0.471
64
Medicine; Health; Psychiatry and Mental Health
Medicine; Social Sciences
2,001
11,509,801
Reduction of the homocysteine plasma concentration by intravenously administered folinic acid and vitamin B(12) in uraemic patients on maintenance haemodialysis.
American journal of nephrology
Am J Nephrol
21
4
10.1159/000046264
eng
2,001
null
null
null
null
null
[BACKGROUND] Hyperhomocysteinaemia is an independent cardiovascular risk factor which can induce vascular lesions, thus contributing to the early development of atherosclerosis. Low-dose folic acid supplementation reduces the pretreatment homocysteine plasma levels by 25-35%. Recent studies report that higher intraveno...
null
0.449
107
Nephrology
Medicine
2,001
11,509,777
Comparison of tissue injury between laparosonic coagulating shears and electrosurgical scissors in the sheep model.
The Journal of the American Association of Gynecologic Laparoscopists
J Am Assoc Gynecol Laparosc
8
3
10.1016/s1074-3804(05)60334-9
eng
2,001
8
null
null
null
null
[STUDY OBJECTIVE] To compare laparosonic coagulating shears (LCS), which use ultrasonic energy, and unipolar diathermy scissors with respect to depth of tissue injury. [DESIGN] Prospective observational study (Canadian Task Force classification I). [SETTING] A reproduced surgical setting. [SUBJECTS] An anesthetized she...
null
null
null
null
null
null
11,508,750
Bayesian regression methodology for estimating a receiver operating characteristic curve with two radiologic applications: prostate biopsy and spiral CT of ureteral stones.
Academic radiology
Acad Radiol
8
8
10.1016/s1076-6332(03)80578-0
eng
2,001
8
null
null
null
null
[RATIONALE AND OBJECTIVES] The authors evaluated two Bayesian regression models for receiver operating characteristic (ROC) curve analysis of continuous diagnostic outcome data with covariates. [MATERIALS AND METHODS] Full and partial Bayesian regression models were applied to data from two studies (n = 180 and 100, re...
null
0.607
113
Radiology, Nuclear Medicine and Imaging
Medicine
2,001
11,508,591
Total hip arthroplasty in ankylosing spondylitis: outcome in 340 patients.
The Journal of rheumatology
J Rheumatol
28
8
null
eng
2,001
8
null
null
null
null
[OBJECTIVE] The longterm outcome of total hip arthroplasty (THA) in ankylosing spondylitis (AS) remains unclear. Concern has been expressed regarding joint survival, given that recipients are young and active. We present outcome data on 340 THA after a mean followup of 14 years. [METHODS] The 6.7% of patients (n = 309:...
null
1.018
201
Immunology and Allergy; Rheumatology; Immunology
Immunology and Microbiology; Medicine
2,001
11,508,478
The spanish version of the paediatric asthma quality of life questionnaire (PAQLQ): metric characteristics and equivalence with the original version.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Qual Life Res
10
1
10.1023/a:1016622519987
eng
2,001
null
null
null
null
null
[UNLABELLED] The Paediatric Asthma Quality of Life Questionnaire (PAQLQ), developed by Juniper et al., assesses the impact of asthma on children's daily life. It contains 23 items, covering three dimensions: symptoms, activities limitation and emotional function. [AIMS] To develop an equivalent Spanish version of the P...
null
0.794
179
Public Health, Environmental and Occupational Health
Medicine
2,001
11,508,416
The use and maintenance of visible light activating units in general practice.
British dental journal
Br Dent J
191
2
10.1038/sj.bdj.4801103
eng
2,001
7
28
null
null
null
[AIM] The present study to investigate the use, care and maintenance of light units in everyday clinical practice was undertaken to complement light unit emission surveys, with a view to developing a protocol for light unit use and care in everyday clinical practice. [METHOD] The investigative work comprised a survey o...
null
null
null
null
null
null
11,508,178
Changes in the quality of life: a major goal of cardiac rehabilitation.
Journal of cardiopulmonary rehabilitation
J Cardiopulm Rehabil
21
4
10.1097/00008483-200107000-00001
eng
2,001
null
null
null
null
null
[BACKGROUND] Quality of life (QOL) is a major goal in the context of preventive and therapeutic cardiology. In this article, quality of life concepts are reviewed, factors limiting QOL in cardiac disease are identified, methods of measurement are explored, and clinically significant changes are defined. The changes eff...
null
null
null
null
null
null
11,506,519
Intraoperative, perioperative and late complications with endovascular therapy of aortic aneurysm.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Eur J Vasc Endovasc Surg
22
3
10.1053/ejvs.2001.1417
eng
2,001
9
null
null
null
null
[PURPOSE] To describe the incidence and management of the intraoperative, perioperative and late complications of endovascular aortic aneurysm repair. [METHODS] Endovascular aneurysm repair was attempted in 130 patients between October, 1995 and January, 2000. Follow-up including computed tomography (CT) was performed ...
null
1.075
144
Cardiology and Cardiovascular Medicine; Surgery
Medicine
2,001
11,505,494
Two cases of primary malignant melanoma of the lacrimal sac.
Head & neck
Head Neck
23
9
10.1002/hed.1116
eng
2,001
9
null
null
null
null
[BACKGROUND] Malignancy of the lacrimal sac is rare, and primary malignant melanoma in this region is extremely rare. [METHODS] We report two cases of malignant melanoma of the lacrimal sac presented with epiphora and a palpable mass in the medial canthal area. We performed radical surgery and radiation therapy. [RESUL...
null
null
null
null
null
null
11,505,401
Phase II study of gemcitabine and cisplatin in the treatment of patients with advanced pancreatic carcinoma.
Cancer
Cancer
92
3
10.1002/1097-0142(20010801)92:3<569::aid-cncr1356>3.0.co;2-d
eng
2,001
8
1
null
null
null
[BACKGROUND] Pancreatic carcinoma is considered among the most chemoresistant of human malignancies. The most commonly used cytotoxic single agents, 5-fluorouracil and 2'-deoxy-2',2'-difluorocytidine (gemcitabine), have objective response rates of less than 10% in large studies. Hypothesizing noncross resistance and a ...
null
1.593
349
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,505,031
Influence of alcohol intake on risk for increased low-density lipoprotein cholesterol in middle-aged Japanese men.
Alcoholism, clinical and experimental research
Alcohol Clin Exp Res
25
7
null
eng
2,001
7
null
null
null
null
[BACKGROUND] Decreased low-density lipoprotein (LDL) cholesterol in chronic alcoholics is well known. However, the importance of light to moderate alcohol consumption is less certain. [METHODS] We investigated the association of alcohol intake with risk for increased LDL cholesterol over 5 years in a cohort of 933 Japa...
null
null
null
null
null
null
11,503,037
The effect of coxsackie virus B3 on intracellular calcium homeostasis in rat cardiomyocytes.
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
14
2
null
eng
2,000
6
null
null
null
null
[OBJECTIVE] To investigate the effect of coxsackievirus B3 (CVB3) on intracellular calcium, L type voltage dependent calcium channel (VDCC) and Na+/Ca2+ exchange (NCE) in adult rat cardiomyocytes. [METHODS] Rat hearts were perfused with collagenase to gain single cardiomyocyte. The intracellular free calcium concentrat...
null
null
null
null
null
null
11,502,972
Effect of Bw4 and Bw6 epitope mismatches on antibody production, acute and chronic rejection, and graft survival in renal allografts.
Transplantation
Transplantation
72
3
10.1097/00007890-200108150-00013
eng
2,001
8
15
null
null
null
[BACKGROUND] Highly sensitized patients often have antibodies directed against the HLA Bw4 and Bw6 epitopes. Because of the high frequency of these epitopes, when present, these antibodies result in a high incidence of positive cross-matches. We sought to determine whether antibodies specific for Bw4 or Bw6 affected re...
null
1.782
224
Transplantation
Medicine
2,001
11,502,696
Functional evidence for a role of vascular chymase in the production of angiotensin II in isolated human arteries.
Circulation
Circulation
104
7
10.1161/hc3201.094971
eng
2,001
8
14
null
null
null
[BACKGROUND] In human arteries, angiotensin-converting enzyme (ACE) inhibitors incompletely block the production of angiotensin (Ang) II from Ang I. This ACE-independent production of Ang II appears to be caused by serine proteases, one of which presumably is chymase. However, several serine proteases may produce Ang I...
null
5.548
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,001
11,501,962
Time-domain analysis of exercise-induced ST-segment elevation in Q-wave myocardial infarction: a useful tool for the screening of myocardial viability.
Italian heart journal : official journal of the Italian Federation of Cardiology
Ital Heart J
2
7
null
eng
2,001
7
null
null
null
null
[BACKGROUND] Exercise-induced ST-segment elevation in Q-wave leads has been traditionally associated with passive stretching of the infarct wall, perinecrotic ischemia and, according to recent scintigraphic studies, with myocardial viability. At present, however, no definitive conclusions are available. We evaluated th...
null
null
null
null
null
null
11,501,750
Over-expression of beta-1,4-galactosyltransferase I, II, and V in human astrocytoma.
Journal of cancer research and clinical oncology
J Cancer Res Clin Oncol
127
8
10.1007/s004320100246
eng
2,001
8
null
null
null
null
[PURPOSE] beta-1,4-Galactosyltransferase (beta-1,4-GalT) I, II, and V are the enzymes responsible for the biosynthesis of N-acetyllactosamine on N-glycans by transferring UDP-galactose to the terminal N-acetylglucosamine (N-GlcNAc) residues with the formation of a beta-1,4-linkage. Neoplasms undergo various changes in ...
null
0.705
114
Medicine; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,500,853
Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein.
Cytometry
Cytometry
44
4
10.1002/1097-0320(20010801)44:4<361::aid-cyto1128>3.0.co;2-3
eng
2,001
8
1
null
null
null
[BACKGROUND] Fluorescence resonance energy transfer (FRET) is a powerful technique for measuring molecular interactions at Angstrom distances. We present a new method for FRET that utilizes the unique spectral properties of variants of the green fluorescent protein (GFP) for large-scale analysis by flow cytometry. [MET...
null
null
null
null
null
null
11,500,702
Effect of labor duration on fetal fibrinolysis: a pilot study.
Saudi medical journal
Saudi Med J
21
6
null
eng
2,000
6
null
null
null
null
[OBJECTIVE] Activation of neonatal and maternal fibrinolysis at birth has been shown earlier. To evaluate further on the effect of labor duration on the fetal fibrinolysis, we conducted this preliminary study. [METHODS] An indirect assessment of activation of fetal fibrinolysis was carried out, by measuring the cord bl...
null
null
null
null
null
null
11,500,676
Subclinical diabetic neuropathy: a common complication in Saudi diabetics.
Saudi medical journal
Saudi Med J
21
5
null
eng
2,000
5
null
null
null
null
[OBJECTIVE] To determine the prevalence of sub clinical diabetic neuropathy in Saudi diabetics and the risk factors associated with symptomatic diabetic neuropathy. [METHODS] A prospective study of Saudi diabetics attending King Abdulaziz University Hospital out patient clinic from January 1998 until April 1999. Detail...
null
null
null
null
null
null
11,499,745
Blood pressure reductions with exercise and sodium restriction in postmenopausal women with elevated systolic pressure: role of arterial stiffness.
Journal of the American College of Cardiology
J Am Coll Cardiol
38
2
10.1016/s0735-1097(01)01348-1
eng
2,001
8
null
null
null
null
[OBJECTIVES] This study determined the relative efficacy of aerobic exercise (daily walking) and moderate dietary sodium restriction (sodium intake <100 mmol/day) for reducing systolic blood pressure (SBP) and pulse pressure (PP) in postmenopausal women with elevated initial levels, and the potential role of reductions...
null
4.039
512
Cardiology and Cardiovascular Medicine
Medicine
2,001
11,483,076
Multicenter Trial of Cryotherapy for Retinopathy of Prematurity: ophthalmological outcomes at 10 years.
Archives of ophthalmology (Chicago, Ill. : 1960)
Arch Ophthalmol
119
8
10.1001/archopht.119.8.1110
eng
2,001
8
null
null
null
null
[OBJECTIVE] To evaluate outcomes at 10 years after randomization for eyes undergoing cryotherapy vs eyes serving as controls, for patients enrolled in the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity (CRYO-ROP). [METHODS] The randomized cohort originally consisted of 291 preterm children with birth w...
null
null
null
null
null
null
11,498,719
Comparative effects of melatonin, zolpidem and diazepam on sleep, body temperature, blood pressure and heart rate measured by radiotelemetry in Wistar rats.
Psychopharmacology
Psychopharmacology (Berl)
156
4
10.1007/s002130100769
eng
2,001
8
null
null
null
null
[RATIONALE] The role of melatonin (MLT) in mediating the sleep-wake cycle has been previously suspected of indicating that this substance could be a candidate for a new generation of hypnotics. [OBJECTIVES] We investigated whether MLT acted as a sleep promoter or a modulator of sleep temporal timing related to cardiova...
null
1.42
218
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,001
11,498,687
Experimental infection of a novel nonenveloped DNA hepatitis virus in Rhesus monkey.
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
14
3
null
eng
2,000
9
null
null
null
null
[OBJECTIVE] To test the susceptibility of the Rhesus monkey to the TT virus and to establish its transmission route. [METHODS] Rhesus monkeys were administered orally and intravenously with the inoculum that was prepared with feces collected from a patient at the incubation period. Passage study was done with monkey' s...
null
null
null
null
null
null
11,498,438
Endovascular management of vein of Galen aneurysmal malformations presenting in the neonatal period.
AJNR. American journal of neuroradiology
AJNR Am J Neuroradiol
22
7
null
eng
2,001
8
null
null
null
null
[BACKGROUND AND PURPOSE] Neonates with vein of Galen aneurysmal malformations (VGAMs) presenting with cardiac failure have high morbidity and mortality, and outcomes are significantly better in those presenting in later childhood. Neurologic outcomes in survivors are perceived to be uniformly poor, which may lead to th...
null
null
null
null
null
null
11,498,082
Evaluation and comparison of therapeutic monitoring of whole-blood levels of cyclosporin A and its metabolites in renal transplantation by HPLC and RIA methods.
Clinica chimica acta; international journal of clinical chemistry
Clin Chim Acta
310
2
10.1016/s0009-8981(01)00570-8
eng
2,001
8
20
null
null
null
[BACKGROUND] The aim of the work was to evaluate the possibility to estimate the level of cyclosporin A (CyA) metabolites as the difference of radioimmunoassay (RIA) non-specific and RIA specific methods. [METHODS] Blood samples of renal transplant patients were analyzed by three different methods: RIA specific method ...
null
null
null
null
null
null
11,498,079
Development of a bloodspot assay for insulin.
Clinica chimica acta; international journal of clinical chemistry
Clin Chim Acta
310
2
10.1016/s0009-8981(01)00545-9
eng
2,001
8
20
null
null
null
[BACKGROUND] Bloodspot assays for hormones have advantages of ease of collection/transportation, minimal invasiveness and small blood volume. Such an approach would be of use in epidemiological studies of insulin resistance in children and neonates. [METHODS] A two-site chemiluminescent immunoassay for the quantitation...
null
null
null
null
null
null
11,497,482
From artisan to architect: the specialist and systems of provision of diabetes care in 2001.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Endocr Pract
7
4
10.4158/EP.7.4.287
eng
2,001
null
null
null
null
null
[OBJECTIVE] To discuss the future role of the diabetes specialist and the endocrinologist in the care of patients with diabetes. [METHODS] We reviewed the literature on health care systems, integrated approaches to provision of health care, health care in the primary-care setting for patients with chronic illness, and ...
null
0.153
107
Medicine; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,497,459
Oral vaccination of sexually mature pigs with Brucella abortus vaccine strain RB51.
American journal of veterinary research
Am J Vet Res
62
8
10.2460/ajvr.2001.62.1328
eng
2,001
8
null
null
null
null
[OBJECTIVE] To develop a novel oral vaccine delivery system for swine, using the rough vaccine strain of Brucella abortus. [ANIMALS] 56 crossbred pigs from a brucellosis-free facility. [PROCEDURE] In 3 separate experiments, pigs were orally vaccinated with doses of 1 x 10(9) to > 1 x 10(11) CFU of strain RB51 vaccine. ...
null
0.677
105
Medicine; Veterinary
Medicine; Veterinary
2,001
11,497,295
Cellular accumulation determines the activity of three novel tricyclic platinum agents.
Anticancer research
Anticancer Res
21
3B
null
eng
2,001
null
null
null
null
null
[BACKGROUND] Cisplatin (CDDP) is a very useful chemotherapeutic agent, but cellular resistance limits its efficacy in malignant glioma. In order to analyze and overcome this resistance, we synthesized three novel platinum compounds; aminoplatin, methylplatin and oxiplatin, using tricyclic DNA intercalating molecules as...
null
null
null
null
null
null
11,495,138
Intrapocket anesthesia for scaling and root planing: results of a double-blind multicenter trial using lidocaine prilocaine dental gel.
Journal of periodontology
J Periodontol
72
7
10.1902/jop.2001.72.7.895
eng
2,001
7
null
null
null
null
[BACKGROUND] The efficacy of a novel anesthetic gel (lidocaine 25 mg/g plus prilocaine 25 mg/g in thermosetting agents) for non-invasive periodontal pocket anesthesia was evaluated. [METHODS] One hundred twenty-two (122) patients in 8 centers with moderate to severe periodontitis requiring scaling and root planing (SRP...
null
0.998
186
Periodontics
Dentistry
2,001
11,494,986
Dirty questions: Indigenous health and 'Western research'.
Australian and New Zealand journal of public health
Aust N Z J Public Health
25
3
10.1111/j.1467-842x.2001.tb00563.x
eng
2,001
6
null
null
null
null
[OBJECTIVE] This paper explores both Indigenous and non-indigenous critiques of 'Western' research frameworks in an Aboriginal health context. It also discusses the 'reform' of Aboriginal health research practices since the 1980s, particularly in relation to the development of ethical guidelines. [METHOD] The text is b...
null
0.47
92
Public Health, Environmental and Occupational Health
Medicine
2,001
11,494,179
The use of proxies in community integration research.
Archives of physical medicine and rehabilitation
Arch Phys Med Rehabil
82
8
10.1053/apmr.2001.25098
eng
2,001
8
null
null
null
null
[OBJECTIVE] To assess the level of agreement between persons with various disabilities and their proxies in reporting community integration outcomes using the Craig Handicap Assessment and Reporting Technique (CHART). [DESIGN] Reliability study. [SETTING] Participants living in the community for a minimum of 6 months a...
null
0.983
225
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science
Health Professions; Medicine
2,001