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11,889,447 | Is there MHC Class II restriction of the response to MHC Class I in transplant patients? | Transplantation | Transplantation | 73 | 4 | 10.1097/00007890-200202270-00030 | eng | 2,002 | 2 | 27 | null | null | null | [BACKGROUND] In this study, we evaluated distinct HLA-DRB1 alleles to determine class II restriction of the production of HLA-A2-specific antibodies in renal transplant patients. [METHODS] Data from 217 renal transplant patients who received an HLA-A2-mismatched renal graft were analyzed with regard to HLA-A2 humoral r... | null | 1.476 | 224 | Transplantation | Medicine | 2,002 |
11,889,427 | The role of tacrolimus (FK506)-based immunosuppression on bone mineral density and bone turnover after cardiac transplantation: a prospective, longitudinal, randomized, double-blind trial with calcitriol. | Transplantation | Transplantation | 73 | 4 | 10.1097/00007890-200202270-00010 | eng | 2,002 | 2 | 27 | null | null | null | [BACKGROUND] Tacrolimus (FK506) is a new immunosuppressive drug in organ transplantation that has demonstrated experimentally to be more deleterious on bone mineral metabolism than cyclosporine. The purpose of this clinical study was to evaluate the effects of a tacrolimus-based immunosuppression on the skeleton and to... | null | 1.476 | 224 | Transplantation | Medicine | 2,002 |
11,889,423 | TCV-116, an angiotensin II type 1 receptor antagonist, reduces hepatic ischemia-reperfusion injury in rats. | Transplantation | Transplantation | 73 | 4 | 10.1097/00007890-200202270-00006 | eng | 2,002 | 2 | 27 | null | null | null | [BACKGROUND] In Pringle's maneuver during liver surgery and liver transplantation, ischemia-reperfusion (I/R) is an unavoidable process, and protection against hepatic I/R injury is a major unresolved problem. Therefore, various pharmacologic approaches to prevent hepatic I/R injury are currently under trial. In this s... | null | 1.476 | 224 | Transplantation | Medicine | 2,002 |
11,889,392 | Mixed nasal mucus as a model for sinus mucin gene expression studies. | The Laryngoscope | Laryngoscope | 112 | 2 | 10.1097/00005537-200202000-00023 | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVE/HYPOTHESIS] It is necessary to obtain sinus mucus from the paranasal sinus cavities to study mucin gene expression occurring in the sinuses during chronic sinusitis. This requires an invasive procedure to access the sinus cavity. There are embryological as well as histological similarities between nasal and ... | null | 1.395 | 183 | Otorhinolaryngology | Medicine | 2,002 |
11,889,235 | Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy. | Neurology | Neurology | 58 | 5 | 10.1212/wnl.58.5.730 | eng | 2,002 | 3 | 12 | null | null | null | [BACKGROUND] White matter vacuolization of the spinal cord is common in patients with AIDS and may lead to clinical manifestations of myelopathy. The pathogenesis of AIDS-associated myelopathy (AM) is unknown and may be related to metabolic abnormalities rather than to direct HIV infection. The striking pathologic simi... | null | 2.373 | 422 | Neurology | Medicine | 2,002 |
11,888,874 | Analysis of nipple/areolar involvement with mastectomy: can the areola be preserved? | Annals of surgical oncology | Ann Surg Oncol | 9 | 2 | 10.1007/BF02557369 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Skin-sparing mastectomy (SSM), which involves the resection of the nipple/areolar complex with the breast parenchyma, improves the aesthetic outcome for breast cancer patients. Most patients undergoing SSM desire reconstruction of the nipple/areolar complex for symmetry. These data explore the possibility ... | null | 1.483 | 210 | Oncology; Surgery | Medicine | 2,002 |
11,888,760 | Myocardial injury in hypertrophic hearts of patients undergoing aortic valve surgery using cold or warm blood cardioplegia. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery | Eur J Cardiothorac Surg | 21 | 3 | 10.1016/s1010-7940(01)01168-x | eng | 2,002 | 3 | null | null | null | null | [OBJECTIVES] Myocardial protection techniques during cardiac surgery have been largely investigated in the clinical setting of coronary revascularisation. Few studies have been carried out on patients with left ventricular hypertrophy where the choice of delivery, and temperature of cardioplegia remain controversial. T... | null | 1.163 | 158 | Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,002 |
11,888,127 | Pepsin as a marker for pulmonary aspiration. | American journal of critical care : an official publication, American Association of Critical-Care Nurses | Am J Crit Care | 11 | 2 | null | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Although assessment for aspiration of small volumes of gastric contents in tube-fed patients receiving mechanical ventilation is important, available methods for this purpose are not wholly satisfactory. A potential method is immunoassay of tracheal secretions for the gastric enzyme pepsin. [OBJECTIVES] To... | null | 0.515 | 95 | Critical Care Nursing; Medicine | Medicine; Nursing | 2,002 |
11,888,095 | Intrauterine 10 microg and 20 microg levonorgestrel systems in postmenopausal women receiving oral oestrogen replacement therapy: clinical, endometrial and metabolic response. | BJOG : an international journal of obstetrics and gynaecology | BJOG | 109 | 2 | 10.1111/j.1471-0528.2002.01167.x | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVE] The clinical and endometrial efficacy and lipid response of two different doses of intrauterine levonorgestrel were assessed in comparison with sequential oral medroxyprogesterone acetate in postmenopausal women receiving continuous oral E2-valerate. [DESIGN] One-year prospective multicentre randomised cont... | null | 1.091 | 195 | Obstetrics and Gynecology | Medicine | 2,002 |
11,887,427 | Insulin resistance, ventricular mass and function in normoglycaemic hypertensives. | Nutrition, metabolism, and cardiovascular diseases : NMCD | Nutr Metab Cardiovasc Dis | 11 | 5 | null | eng | 2,001 | 10 | null | null | null | null | [BACKGROUND AND AIM] To investigate the possible relationship between insulin sensitivity and the main non-invasively determined parameters of left ventricular structure and function in an early phase of hypertensive disease. [METHODS AND RESULTS] We studied a group of 60 patients with previously untreated primary arte... | null | 0.364 | 125 | Cardiology and Cardiovascular Medicine; Medicine; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism | Medicine; Nursing | 2,001 |
11,887,243 | Cumulative effects of cardiovascular disease risk factors on quality of life. | The journal of nutrition, health & aging | J Nutr Health Aging | 6 | 3 | null | eng | 2,002 | 5 | null | null | null | null | [OBJECTIVES] The Medical Outcomes Study Short-Form Health Survey (SF-36) was used to assess the quality of life for adults who differed in level of risk for cardiovascular disease. [METHODS] Subjects were 51 men and 80 women from southwestern Ohio between the ages of 20 and 86 years. Individuals level of risk was based... | null | null | null | null | null | null |
11,887,241 | Nutritional considerations for bereavement and coping with grief. | The journal of nutrition, health & aging | J Nutr Health Aging | 6 | 3 | null | eng | 2,002 | 5 | null | null | null | null | [PURPOSE] The purposes were 1) to examine the level of nutritional risk among recently bereaved individuals, with or without intervention for grief resolution, and those in coupled relationships and 2) to examine the dietary issues faced by the three groups. [METHODS] Twenty-two individuals from the above-mentioned cat... | null | null | null | null | null | null |
11,886,431 | Labile iron in parenteral iron formulations and its potential for generating plasma nontransferrin-bound iron in dialysis patients. | European journal of clinical investigation | Eur J Clin Invest | 32 Suppl 1 | null | 10.1046/j.1365-2362.2002.0320s1042.x | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Labile plasma iron (LPI) associated with iron supplementation has been implicated in complications found in dialysis patients. As LPI can potentially catalyse oxygen radical generation, we determined the presence of labile iron in the parenteral preparations and the frequency of occurrence of LPI in dialys... | null | 0.907 | 126 | Clinical Biochemistry; Medicine; Biochemistry | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,886,349 | Effect of blood transfusion in an experimental sarcoma model. | Archives of otolaryngology--head & neck surgery | Arch Otolaryngol Head Neck Surg | 128 | 3 | 10.1001/archotol.128.3.308 | eng | 2,002 | 3 | null | null | null | null | [OBJECTIVE] To study the effect of allogeneic, syngeneic, and autologous blood transfusion on the growth rate of the KHT tumor in a C3H murine model. [DESIGN] Prospective, randomized, and controlled animal study. [SUBJECTS] Sixty-one C3H female mice. [INTERVENTIONS] The C3H female mice were implanted with 2 x 10(5) cel... | null | null | null | null | null | null |
11,886,004 | Heated intra-operative intraperitoneal oxaliplatin after complete resection of peritoneal carcinomatosis: pharmacokinetics and tissue distribution. | Annals of oncology : official journal of the European Society for Medical Oncology | Ann Oncol | 13 | 2 | 10.1093/annonc/mdf019 | eng | 2,002 | 2 | null | null | null | null | [PURPOSE] This article reports the pharmacokinetics (PK) of heated intra-operative intraperitoneal oxaliplatin and its tolerance profile. Oxaliplatin has demonstrated significant activity in advanced colorectal cancer, and this is the first publication concerning its intraperitoneal administration. [METHODS] Twenty con... | null | 1.073 | 311 | Hematology; Medicine; Oncology | Medicine | 2,002 |
11,886,001 | Weekly chemotherapy with docetaxel, gemcitabine and cisplatin in advanced transitional cell urothelial cancer: a phase II trial. | Annals of oncology : official journal of the European Society for Medical Oncology | Ann Oncol | 13 | 2 | 10.1093/annonc/mdf017 | eng | 2,002 | 2 | null | null | null | null | [PURPOSE] To evaluate the efficacy and toxicity of a combination of weekly docetaxel, gemcitabine and cisplatin in advanced transitional cell carcinoma (TCC) of the bladder. [PATIENTS AND METHODS] Thirty-five chemotherapy-naïve (adjuvant and neoadjuvant chemotherapy was allowed) patients with advanced TCC received intr... | null | 1.073 | 311 | Hematology; Medicine; Oncology | Medicine | 2,002 |
11,885,496 | Steroid-induced osteoporosis. | Annals of the Academy of Medicine, Singapore | Ann Acad Med Singap | 31 | 1 | null | eng | 2,002 | 1 | null | null | null | null | [INTRODUCTION] Corticosteroids have major effects on calcium metabolism, leading to accelerated osteoporosis and fracture. [METHODS] This review will attempt to summarise current knowledge about their effects in light of new information and important remaining questions, especially with respect to management of this co... | null | 0.191 | 70 | Medicine | Medicine | 2,002 |
11,884,920 | Diverging intramuscular activity patterns in back and abdominal muscles during trunk rotation. | Spine | Spine (Phila Pa 1976) | 27 | 6 | 10.1097/00007632-200203150-00014 | eng | 2,002 | 3 | 15 | null | null | null | [STUDY DESIGN] An intramuscular electromyographic study was performed on trunk rotations during sitting and standing. [OBJECTIVE] The aim was to provide new information on activation levels for deep trunk muscles in various unresisted and resisted trunk rotations. [SUMMARY AND BACKGROUND DATA] Frequent daily trunk twis... | null | 1.336 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,002 |
11,884,902 | A randomized controlled trial of two strategies to implement active sick leave for patients with low back pain. | Spine | Spine (Phila Pa 1976) | 27 | 6 | 10.1097/00007632-200203150-00002 | eng | 2,002 | 3 | 15 | null | null | null | [STUDY DESIGN] Cluster randomized controlled trial. [OBJECTIVE] To evaluate the effectiveness of two strategies to improve the use of active sick leave (ASL) for patients with low back pain. [SUMMARY OF BACKGROUND DATA] ASL is a public sickness benefit scheme offered to promote early return to modified work for tempora... | null | 1.336 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,002 |
11,884,880 | Comparison of nonmydriatic digitized video fundus images with standard 35-mm slides to screen for and identify specific lesions of age-related macular degeneration. | Retina (Philadelphia, Pa.) | Retina | 22 | 1 | 10.1097/00006982-200202000-00011 | eng | 2,002 | 2 | null | null | null | null | [PURPOSE] The purpose of this study was to compare nonmydriatic digitized images obtained using a digital imaging system (resolution of 640 x 480 pixels) with 35-mm slide images for detecting specific findings of age-related macular degeneration (AMD) and to evaluate its usefulness as a screening tool in detecting sign... | null | 0.886 | 149 | Medicine; Ophthalmology | Medicine | 2,002 |
11,883,764 | Threshold, comfortable level and impedance changes as a function of electrode-modiolar distance. | Ear and hearing | Ear Hear | 23 | 1 Suppl | 10.1097/00003446-200202001-00004 | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVE] The study investigated the hypothesis that threshold and comfortable levels recorded from cochlear implant patients would reduce, and dynamic range increase, as distance of the electrode from the modiolar wall (radial distance) decreases. Two groups of cochlear implant patients participated; one group using... | null | null | null | null | null | null |
11,883,384 | Model-based administration of inhalation anaesthesia. 4. Applying the system model. | British journal of anaesthesia | Br J Anaesth | 88 | 2 | 10.1093/bja/88.2.175 | eng | 2,002 | 2 | null | null | null | null | [BACKGROUND] We developed and tested a simple dosing strategy for rapid induction with isoflurane followed by maintenance under minimal-flow conditions, that is 0.5 litre min(-1) total fresh gas flow (FGF). An end-expired concentration was to be achieved within 5 min in a desired therapeutic window, that is 0.8-1.1 vol... | null | 1.142 | 222 | Anesthesiology and Pain Medicine | Medicine | 2,002 |
11,882,827 | Delayed detection of motor pathway dysfunction after selective reduction of thoracic spinal cord blood flow in pigs. | The Journal of thoracic and cardiovascular surgery | J Thorac Cardiovasc Surg | 123 | 3 | 10.1067/mtc.2002.118048 | eng | 2,002 | 3 | null | null | null | null | [OBJECTIVE] Clinical monitoring of myogenic motor evoked potentials to transcranial stimulation provides rapid evaluation of motor-pathway function during surgical procedures in which spinal cord ischemia can occur. However, a severe reduction of spinal cord blood flow that remains confined to the thoracic spinal cord ... | null | 1.904 | 225 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,002 |
11,881,840 | Clozapine-associated elevation of plasma cholinesterase. | European archives of psychiatry and clinical neuroscience | Eur Arch Psychiatry Clin Neurosci | 251 | 6 | 10.1007/pl00007544 | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] The goal of this study was to identify adverse effects of the atypical neuroleptic clozapine on liver function and lipid metabolism. [METHODS] Data which included serum levels of clozapine and its hepatic metabolite N-desmethyl clozapine were collected from medical records of patients treated with clozapine... | null | null | null | null | null | null |
11,880,821 | Creatine supplementation improves muscular performance in older men. | Medicine and science in sports and exercise | Med Sci Sports Exerc | 34 | 3 | 10.1097/00005768-200203000-00023 | eng | 2,002 | 3 | null | null | null | null | [PURPOSE] Creatine supplementation has been shown to enhance muscle strength and power after only 5-7 d in young adults. Creatine supplementation could therefore benefit older individuals because aging is associated with a decrease in muscle strength and explosive power. [METHODS] We examined the effects of 7 d of crea... | null | 1.429 | 271 | Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science | Health Professions; Medicine | 2,002 |
11,880,779 | Minimal versus maximal plate fixation techniques of the ulna: the biomechanical effect of number of screws and plate length. | Journal of orthopaedic trauma | J Orthop Trauma | 16 | 3 | 10.1097/00005131-200203000-00005 | eng | 2,002 | 3 | null | null | null | null | [OBJECTIVE] To test the hypothesis that longer plates with the minimum number of screws provide equivalent or superior strength of fixation to standard compression plating using the maximum number of screws. [DESIGN] Prospective analysis of biomechanical data was performed. [SETTING] In vitro experimentation. [INTERVEN... | null | 0.947 | 150 | Medicine; Orthopedics and Sports Medicine; Sports Science; Surgery | Health Professions; Medicine | 2,002 |
11,879,453 | Knowledge of diabetes among personnel in home-based care: how does it relate to medical mishaps? | Journal of nursing management | J Nurs Manag | 9 | 2 | 10.1046/j.1365-2834.2001.00217.x | eng | 2,001 | 3 | null | null | null | null | [OBJECTIVE] To assess the influence of knowledge about diabetes on the performance of diabetes care for the elderly involving insulin treatment, with special attention to aspects of patient safety in home care. [DESIGN] A questionnaire was administered to nurse's aides and assistant nurses (n = 3144). Answers to questi... | null | 0.353 | 103 | Leadership and Management | Nursing | 2,001 |
11,877,692 | Long-term outcome after mesenteric artery reconstruction: a 37-year experience. | Journal of vascular surgery | J Vasc Surg | 35 | 3 | 10.1067/mva.2002.118593 | eng | 2,002 | 3 | null | null | null | null | [PURPOSE] The purpose of this study was the definition of the late results and determining factors after mesenteric artery reconstruction (MAR) for atherosclerotic mesenteric ischemia. [METHODS] A retrospective review identified 48 consecutive patients (66 arteries) who underwent MAR for acute mesenteric ischemia (AMI)... | null | 1.767 | 225 | Cardiology and Cardiovascular Medicine; Surgery | Medicine | 2,002 |
11,875,635 | Sex and rat strain determine sensitivity to kappa opioid-induced antinociception. | Psychopharmacology | Psychopharmacology (Berl) | 160 | 2 | 10.1007/s00213-001-0949-2 | eng | 2,002 | 3 | null | 2,001 | 12 | 20 | [RATIONALE] Recent studies indicate that sex and rodent strain are determinants of sensitivity to opioid-induced antinociception. [OBJECTIVES] The present study examined the influence of sex and rat strain on kappa opioid-induced antinociception using a series of kappa opioids that vary in their relative effectiveness.... | null | 1.66 | 218 | Pharmacology | Pharmacology, Toxicology and Pharmaceutics | 2,002 |
11,875,086 | Main portal vein access in transjugular intrahepatic portosystemic shunt procedures: use of three-dimensional ultrasound to ensure safety. | Journal of vascular and interventional radiology : JVIR | J Vasc Interv Radiol | 13 | 3 | 10.1016/s1051-0443(07)61719-9 | eng | 2,002 | 3 | null | null | null | null | [PURPOSE] To document the safety of main portal vein (PV) access to create transjugular portosystemic intrahepatic shunts (TIPS), provided that three-dimensional ultrasonography (3D US) can document the puncture to have entered a surface of the PV suitable for tamponade. [MATERIALS AND METHODS] In 11 patients who under... | null | 1.037 | 150 | Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,002 |
11,874,763 | Posterior segment changes associated with posterior microphthalmos. | Ophthalmology | Ophthalmology | 109 | 3 | 10.1016/s0161-6420(01)00996-4 | eng | 2,002 | 3 | null | null | null | null | [PURPOSE] To characterize and analyze the posterior segment ocular involvement in patients with posterior microphthalmos. [DESIGN] Retrospective observational case series. [PARTICIPANTS] Eighteen patients (8 sporadic cases and 10 siblings from 5 different families) between the age of 4 and 36 years with posterior micro... | null | 2.479 | 297 | Ophthalmology | Medicine | 2,002 |
11,874,759 | Human papillomavirus 16 and 18 expression in conjunctival intraepithelial neoplasia. | Ophthalmology | Ophthalmology | 109 | 3 | 10.1016/s0161-6420(01)00991-5 | eng | 2,002 | 3 | null | null | null | null | [OBJECTIVE] To evaluate conjunctival intraepithelial neoplasia (CIN) and normal conjunctiva for the presence of human papillomavirus (HPV) DNA and for expression (as detected by the presence of mRNA) of the HPV E6 region. [DESIGN] Prospective, case-controlled study. [PARTICIPANTS] Ten consecutive patients who underwent... | null | 2.479 | 297 | Ophthalmology | Medicine | 2,002 |
11,874,620 | Prediction equations for handgrip strength in healthy Indian male and female subjects encompassing a wide age range. | Annals of human biology | Ann Hum Biol | 29 | 2 | 10.1080/03014460110058962 | eng | 2,002 | null | null | null | null | null | [PRIMARY OBJECTIVE] Handgrip strength is a simple index of skeletal muscle function and a functional index of nutritional status. A major lacuna in the use of handgrip strength is the limited availability of normative data. The main objective of this paper was to develop prediction equations for handgrip strength in In... | null | 0.468 | 70 | Aging; Public Health, Environmental and Occupational Health; Epidemiology; Genetics; Physiology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,874,535 | Development of a high-volume aerosol collection system for the identification of air-borne micro-organisms. | Letters in applied microbiology | Lett Appl Microbiol | 34 | 3 | 10.1046/j.1472-765x.2002.01048.x | eng | 2,002 | null | null | null | null | null | [AIMS] A high-volume aerosol collector was developed to efficiently capture airborne bacteria in order to assess levels of diversity in the air. [METHODS AND RESULTS] Particulate matter was collected on a device designed to filter 1.4 x 10(6) litres of air in a 24 h period on a 1-microm pore size polyester membrane. Me... | null | 0.647 | 133 | Applied Microbiology and Biotechnology | Immunology and Microbiology | 2,002 |
11,874,072 | Identifying local tumor variables for operable node-negative, margin-free patients with bulky cervical carcinoma of FIGO stage IB, IIA and IIB without adjuvant therapies. | European journal of gynaecological oncology | Eur J Gynaecol Oncol | 22 | 6 | null | eng | 2,001 | null | null | null | null | null | [PURPOSE] To identify local risk factors for FIGO IB, IIA and IIB bulky cervical squamous cell carcinoma (tumor size > or = 4 cm) patients with node-negative, margin-free tumors treated by radical hysterectomy, pelvic lymph node and para-aortic lymph node dissections without adjuvant therapies. [MATERIALS AND METHODS] ... | null | null | null | null | null | null |
11,873,088 | Risk stratification of coronary heart disease through established and emerging lifestyle factors in a Mediterranean population: CARDIO2000 epidemiological study. | Journal of cardiovascular risk | J Cardiovasc Risk | 8 | 6 | 10.1177/174182670100800601 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] In recent decades various lifestyle factors have been associated with the increasing risk of coronary heart disease. The aim of this study is to assess coronary risk, based on established and emerging lifestyle risk factors such as smoking habit, physical activity, alcohol consumption and depression in a M... | null | null | null | null | null | null |
11,873,042 | Ketamine inhibits sodium currents in identified cardiac parasympathetic neurons in nucleus ambiguus. | Anesthesiology | Anesthesiology | 96 | 3 | 10.1097/00000542-200203000-00023 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Ketamine increases both blood pressure and heart rate, effects commonly thought of as sympathoexcitatory. The authors investigated the possibility that ketamine increases heart rate by inhibiting the central cardiac parasympathetic mechanisms. [METHODS] We used a novel in vitro approach to study the effect... | null | null | null | null | null | null |
11,872,517 | Frequent attenders with medically unexplained symptoms: service use and costs in secondary care. | The British journal of psychiatry : the journal of mental science | Br J Psychiatry | 180 | null | 10.1192/bjp.180.3.248 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Frequent attenders in medical settings account for a disproportionate amount of health-care resources. Little is known about service use and costs of secondary care in those frequent attenders presenting with medically unexplained symptoms. [AIMS] To compare health-care use and costs of patients with medic... | null | 2.874 | 264 | Medicine; Psychiatry and Mental Health | Medicine | 2,002 |
11,872,298 | Consensus guidelines for radiation therapy of benign diseases: a multicenter approach in Germany. | International journal of radiation oncology, biology, physics | Int J Radiat Oncol Biol Phys | 52 | 2 | 10.1016/s0360-3016(01)01814-4 | eng | 2,002 | 2 | 1 | null | null | null | [PURPOSE] To overcome the lack of written guidelines for radiation therapy (RT) of benign diseases, the German Working Group on Radiotherapy of Benign Diseases initiated a consensus process in 1999 to warrant continuous quality assurance and outcome research in this field. [METHODS] An expert panel was convened to defi... | null | 1.712 | 286 | Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging | Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy | 2,002 |
11,872,219 | Estrogen replacement therapy induces telomerase RNA expression in the macaque endometrium. | Fertility and sterility | Fertil Steril | 77 | 3 | 10.1016/s0015-0282(01)03227-7 | eng | 2,002 | 3 | null | null | null | null | [OBJECTIVE] To evaluate the effects of hormonal therapies on the expression of telomerase RNA (TRNA) in the endometrium of ovariectomized female cynomolgus macaques (Macaca fascicularis). [DESIGN] Randomized long-term experimental trial. [SETTING] Animal study at an academic research institution. [PATIENT(S)] Surgicall... | null | 1.385 | 252 | Obstetrics and Gynecology; Reproductive Medicine | Medicine | 2,002 |
11,982,660 | Failure of timed bright light exposure to alleviate age-related sleep maintenance insomnia. | Journal of the American Geriatrics Society | J Am Geriatr Soc | 50 | 4 | 10.1046/j.1532-5415.2002.50154.x | eng | 2,002 | 4 | null | null | null | null | [OBJECTIVES] To determine whether a twice-weekly maintenance schedule of evening bright light exposure is effective in alleviating sleep maintenance insomnia on a long-term basis, after the establishment of a more favorable phase relationship between the core body temperature (CBT) rhythm and sleep. [DESIGN] Subjects u... | null | 1.748 | 273 | Geriatrics and Gerontology | Medicine | 2,002 |
11,982,470 | Primary cancers of the small bowel: analysis of prognostic factors and results of surgical management. | Archives of surgery (Chicago, Ill. : 1960) | Arch Surg | 137 | 5 | 10.1001/archsurg.137.5.564 | eng | 2,002 | 5 | null | null | null | null | [HYPOTHESIS] This study was done to review the clinical presentation, surgical management, pathologic features, and prognostic factors for primary small-bowel cancers. [DESIGN] Retrospective case series. [SETTING] Tertiary care, university hospital. [PATIENTS] One hundred twenty-nine patients were surgically treated be... | null | null | null | null | null | null |
11,981,679 | Revision of the multiple organ failure score. | Langenbeck's archives of surgery | Langenbecks Arch Surg | 387 | 1 | 10.1007/s00423-001-0269-3 | eng | 2,002 | 4 | null | 2,002 | 1 | 31 | [BACKGROUND AND AIM] The multiple organ failure (MOF) score published by Goris et al. in 1985 was one of the first attempts to quantify severity of organ dysfunction and failure based on expert opinion in surgical intensive care unit patients. Fifteen years later a reassessment of this score is mandatory. [PATIENTS AND... | null | 0.574 | 94 | Surgery | Medicine | 2,002 |
11,981,672 | Vibrotactile sense and mechanical functional state of the arm and hand among computer users compared with a control group. | International archives of occupational and environmental health | Int Arch Occup Environ Health | 75 | 5 | 10.1007/s00420-001-0301-5 | eng | 2,002 | 6 | null | 2,002 | 2 | 19 | [OBJECTIVES] To measure sensory perception and mechanical muscle function of the arm among experienced female computer users with (+sPC) and without (-sPC) symptoms compared with a control group (ctrl). [METHODS] Group +sPC had severe symptoms in the hand/wrist and/or the forearm/elbow region. They worked with the comp... | null | 0.607 | 105 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
11,981,662 | Carcinogen-specific mutation pattern in the p53 tumour suppressor gene in UV radiation-induced basal cell carcinoma. | International archives of occupational and environmental health | Int Arch Occup Environ Health | 75 | 4 | 10.1007/s00420-001-0307-z | eng | 2,002 | 4 | null | 2,002 | 1 | 26 | [OBJECTIVES] Basal cell carcinoma (BCC) is mainly caused by high and long-term UV radiation. UV radiation causes DNA damage in various genes. Mutations of the p53 tumour suppressor gene have been identified in a wide variety of human cancers. The aim of the study was to analyse specific p53 mutations in BCCs in workers... | null | 0.607 | 105 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
11,981,620 | Vascular endothelial growth factor and erythropoietin concentrations in cerebrospinal fluid of children with hydrocephalus. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery | Childs Nerv Syst | 18 | 3-4 | 10.1007/s00381-002-0567-2 | eng | 2,002 | 4 | null | 2,002 | 3 | 22 | [INTRODUCTION] Hypoxia induces transcription of vascular endothelial growth factor (VEGF) and erythropoietin (EPO) genes. We set up the hypothesis that elevated intracranial pressure in patients with hydrocephalus triggers release of VEGF and EPO into cerebrospinal fluid (CSF). [METHODS AND RESULTS] VEGF and EPO concen... | null | 0.486 | 100 | Medicine; Neurology; Pediatrics, Perinatology and Child Health | Medicine | 2,002 |
11,981,605 | Normal murine bone morphometry: a comparison of magnetic resonance microscopy with micro X-ray and histology. | Skeletal radiology | Skeletal Radiol | 31 | 5 | 10.1007/s00256-002-0484-1 | eng | 2,002 | 5 | null | 2,002 | 3 | 23 | [OBJECTIVE] The authors have devised a means to assess subtle changes in the structure of bone using magnetic resonance (MR) microscopy. MR microscopy was compared with micro X-ray and histology to analyze the structure of normal bone. [DESIGN] Femurs of C57Bl/6 mice were examined ex vivo using differently orientated s... | null | 0.677 | 108 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,002 |
11,981,342 | Red cell distribution width as a marker of coeliac disease: a prospective study. | European journal of gastroenterology & hepatology | Eur J Gastroenterol Hepatol | 14 | 2 | 10.1097/00042737-200202000-00012 | eng | 2,002 | 2 | null | null | null | null | [BACKGROUND] Coeliac disease is frequently underdiagnosed because of its protean presentations. Serological tests may be helpful in screening programmes for populations at risk, but they are costly. [AIM] To determine prospectively whether a commonly available haematological test such as the red cell distribution width... | null | null | null | null | null | null |
11,981,215 | Thirty-day postoperative death rate at an academic medical center. | Annals of surgery | Ann Surg | 235 | 5 | 10.1097/00000658-200205000-00011 | eng | 2,002 | 5 | null | null | null | null | [OBJECTIVE] To improve understanding of perioperative deaths at an academic medical center. [SUMMARY BACKGROUND DATA] Because published data have typically focused on specific patient populations, diagnoses, or procedures, there are few data regarding surgical deaths and complications in institutional or regional studi... | null | 3.446 | 360 | Surgery | Medicine | 2,002 |
11,980,769 | The effect of a change in the dose of trimegestone on the pattern of bleeding in estrogen-treated post-menopausal women: 6 month extension of a dose-ranging study. | Human reproduction (Oxford, England) | Hum Reprod | 17 | 5 | 10.1093/humrep/17.5.1386 | eng | 2,002 | 5 | null | null | null | null | [BACKGROUND] Abnormal bleeding pattern is one major reason for non-compliance with hormone replacement therapy (HRT) in post-menopausal women. We have previously documented that the dose of trimegestone is the main determinant of the pattern of bleeding in women treated with estradiol (E(2)) and sequential combined tri... | null | 1.501 | 264 | Obstetrics and Gynecology; Rehabilitation; Reproductive Medicine | Medicine | 2,002 |
11,980,754 | Polyploidy in large-headed sperm: FISH study of three cases. | Human reproduction (Oxford, England) | Hum Reprod | 17 | 5 | 10.1093/humrep/17.5.1292 | eng | 2,002 | 5 | null | null | null | null | [BACKGROUND] Macrocephalic or large headed sperm with multiflagella is a rare abnormality often associated with infertility. Sperm chromosomal abnormalities could be associated with this specific morphological abnormality. [METHODS] The cytogenetic content of large-headed sperm was assessed by dual and three-colour flu... | null | 1.501 | 264 | Obstetrics and Gynecology; Rehabilitation; Reproductive Medicine | Medicine | 2,002 |
11,980,748 | Female sex selection using clomiphene citrate and albumin separation of human sperm. | Human reproduction (Oxford, England) | Hum Reprod | 17 | 5 | 10.1093/humrep/17.5.1254 | eng | 2,002 | 5 | null | null | null | null | [BACKGROUND] This study was undertaken to assess whether the use of clomiphene citrate in conjunction with albumin-separated sperm would alter the sex ratio (expressed as the proportion of males) towards females and, if so, whether this skewing was due solely to the induction of ovulation. [METHODS] The sex ratios of 1... | null | 1.501 | 264 | Obstetrics and Gynecology; Rehabilitation; Reproductive Medicine | Medicine | 2,002 |
11,980,741 | Value of measuring serum FSH in addition to serum estradiol in a coasting programme to prevent severe OHSS. | Human reproduction (Oxford, England) | Hum Reprod | 17 | 5 | 10.1093/humrep/17.5.1217 | eng | 2,002 | 5 | null | null | null | null | [BACKGROUND] Withholding gonadotrophins (coasting) can reduce the risk of severe ovarian hyperstimulation syndrome (OHSS) in patients having assisted reproduction therapy. This requires daily serum estradiol (E(2)) measurements, which occasionally have been seen to decline suddenly and sharply. [METHODS] To increase th... | null | 1.501 | 264 | Obstetrics and Gynecology; Rehabilitation; Reproductive Medicine | Medicine | 2,002 |
11,979,169 | Intraoperative measurement of lumbar spine motion segment stiffness. | Spine | Spine (Phila Pa 1976) | 27 | 9 | 10.1097/00007632-200205010-00014 | eng | 2,002 | 5 | 1 | null | null | null | [STUDY DESIGN] Prospective trial. [OBJECTIVES] To test an intraoperative diagnostic tool to determine if it provided the surgeon with a safe, reproducible, accurate, quantitative measure of lumbar spine motion segment stability. [SUMMARY OF BACKGROUND DATA] Several devices have been developed to measure motion segment ... | null | 1.336 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,002 |
11,978,691 | Influence of cardiac autonomic neuropathy on heart rate dependence of ventricular repolarization in diabetic patients. | Diabetes care | Diabetes Care | 25 | 5 | 10.2337/diacare.25.5.918 | eng | 2,002 | 5 | null | null | null | null | [OBJECTIVE] Prolongation of the QT interval and increased QT dispersion are associated with a poor cardiac prognosis. The goal of this study was to assess the long-term influence of the autonomic nervous system on the heart rate dependence of ventricular repolarization in patients with diabetic autonomic neuropathy (DA... | null | 2.924 | 433 | Advanced and Specialized Nursing; Endocrinology, Diabetes and Metabolism; Internal Medicine | Medicine; Nursing | 2,002 |
11,978,460 | Refractive change in pediatric pseudophakia: 6-year follow-up. | Journal of cataract and refractive surgery | J Cataract Refract Surg | 28 | 5 | 10.1016/s0886-3350(01)01156-7 | eng | 2,002 | 5 | null | null | null | null | [PURPOSE] To evaluate the long-term evolution of refractive error changes in eyes of children who have primary intraocular lens (IOL) implantation to allow more accurate prediction of what IOL power should be implanted at a given age. [SETTING] Department of Ophthalmology, Indiana University School of Medicine, Indiana... | null | 1.771 | 169 | Ophthalmology; Sensory Systems; Surgery | Medicine; Neuroscience | 2,002 |
11,978,277 | Prolonged GnRH agonist and add-back therapy for symptomatic endometriosis: long-term follow-up. | Obstetrics and gynecology | Obstet Gynecol | 99 | 5 Pt 1 | 10.1016/s0029-7844(02)01945-2 | eng | 2,002 | 5 | null | null | null | null | [OBJECTIVE] To assess post-treatment effects in endometriosis patients of a 12-month course of GnRH agonist alone or with one of three "add-back" regimens. [METHODS] This is a post-treatment follow-up analysis of a randomized, double-masked, placebo-controlled 52-week trial. All patients had received monthly leuprolide... | null | 1.319 | 268 | Obstetrics and Gynecology | Medicine | 2,002 |
11,976,463 | Impact of daily versus weekly hematinic supplementation on anemia in pregnant women. | Indian pediatrics | Indian Pediatr | 39 | 4 | null | eng | 2,002 | 4 | null | null | null | null | [OBJECTIVE] To compare the effectivity of weekly versus daily iron therapy in reducing maternal anemia and to evaluate the association of maternal hemoglobin and fetal growth. [DESIGN] Prospective. [SETTING] Tertiary care teaching hospital in an urban metropolis. [METHOD] 40 pregnant women received daily and 40 pregnan... | null | 0.215 | 63 | Pediatrics, Perinatology and Child Health | Medicine | 2,002 |
11,974,040 | Clinical decision support tools in A&E nursing: a preliminary study. | Nursing standard (Royal College of Nursing (Great Britain) : 1987) | Nurs Stand | 14 | 34 | 10.7748/ns2000.05.14.34.32.c2836 | eng | null | null | null | null | null | null | [AIM] This article describes how a large trust in the north east of England is in the process of developing a unique service for non-emergency patients in one of its main A&E departments. The Urgent Need Assessment Service (UNAS), co-located within the main A&E department, features the use of NHS Direct computerised al... | null | null | null | null | null | null |
11,973,555 | Use of out-of-hospital variables to predict severity of injury in pediatric patients involved in motor vehicle crashes. | Annals of emergency medicine | Ann Emerg Med | 39 | 5 | 10.1067/mem.2002.123549 | eng | 2,002 | 5 | null | null | null | null | [STUDY OBJECTIVE] We sought to create a clinical decision rule, on the basis of variables available to out-of-hospital personnel, that could be used to accurately predict severe injury in pediatric patients involved in motor vehicle crashes as occupants. [METHODS] We analyzed the National Automotive Sampling System dat... | null | 1.137 | 178 | Emergency Medicine | Medicine | 2,002 |
11,973,438 | A longitudinal study of the treatment of hot flushes: the population study of women in Gothenburg during a quarter of a century. | Menopause (New York, N.Y.) | Menopause | 9 | 3 | 10.1097/00042192-200205000-00003 | eng | 2,002 | null | null | null | null | null | [OBJECTIVE] To describe the prevalence and treatment of hot flushes in premenopausal and postmenopausal women from the 1960s to the 1990s. [DESIGN] This prospective study, based on a random sample of the total female population of 430,000 in Gothenburg, Sweden, was started in 1968, with follow-ups in 1974, 1980, and 19... | null | 1.332 | 125 | Obstetrics and Gynecology | Medicine | 2,002 |
11,973,365 | Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. | The New England journal of medicine | N Engl J Med | 346 | 17 | 10.1056/NEJMoa012835 | eng | 2,002 | 4 | 25 | null | null | null | [BACKGROUND] No single pulmonary-specific variable, including the severity of hypoxemia, has been found to predict the risk of death independently when measured early in the course of the acute respiratory distress syndrome. Because an increase in the pulmonary dead-space fraction has been described in observational st... | null | 9.315 | 1,231 | Medicine | Medicine | 2,002 |
11,973,096 | Corneal astigmatic change after photorefractive keratectomy and photoastigmatic refractive keratectomy. | Journal of cataract and refractive surgery | J Cataract Refract Surg | 28 | 3 | 10.1016/s0886-3350(01)01157-9 | eng | 2,002 | 3 | null | null | null | null | [PURPOSE] To evaluate and compare the efficacy, safety, predictability, and surgically induced astigmatism (SIA) of photorefractive keratectomy (PRK) and photoastigmatic refractive keratectomy (PARK). [SETTING] Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan. [METHODS] In this retrospec... | null | 1.771 | 169 | Ophthalmology; Sensory Systems; Surgery | Medicine; Neuroscience | 2,002 |
11,972,682 | Influence of ciliate protozoa on biochemical changes and hydrolytic enzyme profile in the rumen ecosystem. | Journal of applied microbiology | J Appl Microbiol | 92 | 5 | 10.1046/j.1365-2672.2002.01583.x | eng | 2,002 | null | null | null | null | null | [AIMS] To assess the effect of presence or absence of rumen protozoa on fermentation characteristics and enzyme profile in growing lambs. [METHODS AND RESULTS] Weaner lambs (G1, G2, G3, G4, G5 and G6 groups) were defaunated by oral administration of sodium laurel sulphate (at 8 g 100 kg(-1) body weight). The lambs of G... | null | 0.905 | 195 | Applied Microbiology and Biotechnology; Biotechnology; Medicine | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,002 |
11,972,551 | Radio-guided sentinel node detection for gastric cancer. | The British journal of surgery | Br J Surg | 89 | 5 | 10.1046/j.1365-2168.2002.02065.x | eng | 2,002 | 5 | null | null | null | null | [BACKGROUND] Radio-guided detection of sentinel nodes (SNs) has been used to predict regional metastases in patients with malignant melanoma and breast cancer. However, the validity of the SN hypothesis is still controversial for gastrointestinal cancers including gastric cancer. The aim of this study was to test the f... | null | 1.657 | 234 | Surgery | Medicine | 2,002 |
11,972,482 | Development of new IgE specificities to allergenic components in birch pollen extract during specific immunotherapy studied with immunoblotting and Pharmacia CAP System. | Allergy | Allergy | 57 | 5 | 10.1034/j.1398-9995.2002.13248.x | eng | 2,002 | 5 | null | null | null | null | [BACKGROUND] New IgE sensitizations to proteins in allergen extracts have been shown to occur during allergen-specific immunotherapy (IT). However little is known about the kinetics of the changes in antibody reactivities. [METHODS] Twenty-four allergic children and adults were treated with birch pollen rush IT (RIT). ... | null | 0.966 | 213 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,002 |
11,971,492 | Spirometry for patients prescribed topical beta-blockers. | Nursing standard (Royal College of Nursing (Great Britain) : 1987) | Nurs Stand | 15 | 4 | 10.7748/ns2000.10.15.4.35.c2929 | eng | null | null | null | null | null | null | [AIM] To evaluate the effects of four glaucoma medications on the cardio-respiratory system. [METHOD] All newly diagnosed glaucoma (primary open-angle glaucoma--POAG--or normal tension glaucoma) patients were recruited into a 12-month prospective audit. [RESULTS] The study has resulted in glaucoma patients having a spi... | null | null | null | null | null | null |
11,971,271 | Twin-endoscope scissors resection (T-ESR): a new minimally invasive technique for performing colonic mucosectomy. | Surgical endoscopy | Surg Endosc | 15 | 12 | 10.1007/s00464-001-9021-x | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] Piecemeal resection is currently the safest method for the endoscopic removal of large sessile colonic polyps. However, this method has its limitations, including the quality of the specimen received for histopathology and the need for early follow-up due to the possibility of incomplete resection and recu... | null | 1.165 | 178 | Surgery | Medicine | 2,001 |
11,968,516 | How similar are the smoking and drinking habits of men and women in non-manual jobs? | European journal of public health | Eur J Public Health | 12 | 1 | 10.1093/eurpub/12.1.22 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Men used to be more likely to smoke and drink heavily than women. However, as social roles changed, so have gender differences in health-related behaviours. This paper explores whether gender differences in these behaviours persist or disappear among men and women occupying similar social roles: working in... | null | 0.346 | 118 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
11,966,871 | Removal of mucus for ultrastructural observation of the surface of human gastric epithelium using pronase. | Helicobacter | Helicobacter | 7 | 2 | 10.1046/j.1083-4389.2002.00070.x | eng | 2,002 | 4 | null | null | null | null | [BACKGROUND] Helicobacter pylori adhering to the human gastric epithelium causes gastric diseases such as ulcer, carcinoma and lymphoma. It is thus important to observe in detail both the surface of the epithelial cells and the H. pylori that adhered to it for the elucidation of H. pylori-induced diseases by scanning e... | null | 0.584 | 94 | Gastroenterology; Medicine; Infectious Diseases | Medicine | 2,002 |
11,966,507 | Extra-intestinal manifestations associated with irritable bowel syndrome: a twin study. | Alimentary pharmacology & therapeutics | Aliment Pharmacol Ther | 16 | 5 | 10.1046/j.1365-2036.2002.01254.x | eng | 2,002 | 5 | null | null | null | null | [BACKGROUND] Little is known about the role of genetic and environmental factors in irritable bowel syndrome. Various extra-intestinal manifestations are more prevalent in cases than in controls. Genetic effects may be important in the liability to develop functional bowel disorders. [AIMS] To evaluate the associations... | null | null | null | null | null | null |
11,965,037 | DNA sequencing of viral capsid protein VP-1 region in patients with BK virus interstitial nephritis. | Transplantation | Transplantation | 73 | 7 | 10.1097/00007890-200204150-00013 | eng | 2,002 | 4 | 15 | null | null | null | [BACKGROUND] Mutations in the viral capsid protein VP-1 region are associated with increased pathogenicity of polyomavirus in experimental systems. This study sought to determine whether analogous viral genetic changes occur in human BK virus (BKV) interstitial nephritis (ISN). [METHODS] PCR was used to amplify a 94-bp... | null | 1.476 | 224 | Transplantation | Medicine | 2,002 |
11,964,957 | Effect of renutrition on natural and cell-mediated immune response in infants with severe malnutrition. | Journal of pediatric gastroenterology and nutrition | J Pediatr Gastroenterol Nutr | 34 | 3 | 10.1097/00005176-200203000-00015 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] The purpose of this study was to evaluate whether a 4-week nutritional recovery period with a starting infant formula and 3.35 kJ/mL energy density would favorably affect the natural and cell-mediated immune response in infants with severe and primary protein-energy malnutrition. [METHODOLOGY] The study in... | null | 0.508 | 160 | Gastroenterology; Pediatrics, Perinatology and Child Health | Medicine | 2,002 |
11,963,836 | Fetal responses to intra-amniotic endotoxin in sheep. | Journal of the Society for Gynecologic Investigation | J Soc Gynecol Investig | 9 | 2 | 10.1016/s1071-5576(01)00155-1 | eng | 2,002 | null | null | null | null | null | [OBJECTIVE] Our aim was to determine the acute physiologic effects of intra-amniotic endotoxin administration in fetal sheep, and in particular, to determine whether intra-amniotic endotoxin causes an increase in fetal cortisol that could underlie the functional maturation of the fetal lungs previously reported in this... | null | null | null | null | null | null |
11,963,521 | Sun protection among parents and children at freshwater beaches. | Canadian journal of public health = Revue canadienne de sante publique | Can J Public Health | 93 | 2 | 10.1007/BF03404557 | eng | 2,002 | null | null | null | null | null | [OBJECTIVES] This paper describes the sun-related behaviour of parents and their children, ages 5-12 years. [METHODS] In-person interviews were conducted with parents and observations of parents and their children to ascertain: 1) parents' self-reported use of sunscreen, 2) parent-proxy reports of children's sunscreen ... | null | null | null | null | null | null |
11,961,620 | Bidirectional endoscopy in patients with fecal occult blood. | Surgical endoscopy | Surg Endosc | 16 | 1 | 10.1007/s004640080183 | eng | 2,002 | 1 | null | 2,001 | 10 | 5 | [BACKGROUND] Current screening protocols for colorectal cancer depend primarily on fecal occult blood testing (FOBT). However, positive test results do not always indicate the presence of a colonic neoplasm. [METHODS] We reviewed the results of 100 consecutive bidirectional (upper and lower) endoscopic procedures perfo... | null | 1.035 | 178 | Surgery | Medicine | 2,002 |
11,961,618 | Impact of upper endoscopic survey during percutaneous endoscopic gastrostomy tube placement. | Surgical endoscopy | Surg Endosc | 16 | 1 | 10.1007/s00464-001-8101-2 | eng | 2,002 | 1 | null | 2,001 | 10 | 13 | [BACKGROUND] No consensus exists concerning the utility of a full diagnostic upper endoscopy during percutaneous endoscopic gastrostomy (PEG) tube placement. We evaluate the effect of a complete survey on identifying and treating unsuspected gastrointestinal pathology. [METHODS] During a 10-year period (1990-2000), 1,7... | null | 1.035 | 178 | Surgery | Medicine | 2,002 |
11,961,483 | Enzyme leakage, trypsinogen activation, and inflammatory response in endoscopic retrograde cholangiopancreatography-induced pancreatitis. | Pancreas | Pancreas | 24 | 4 | 10.1097/00006676-200205000-00001 | eng | 2,002 | 5 | null | null | null | null | [INTRODUCTION] Endoscopic retrograde cholangiopancreatography (ERCP)-induced pancreatitis (EIP) provides an opportunity to study different pathophysiologic events early in the course of acute pancreatitis. [AIMS] To investigate whether the leakage of pancreatic proenzymes (anionic trypsinogen), pancreatic protease acti... | null | 0.576 | 123 | Endocrinology; Endocrinology, Diabetes and Metabolism; Hepatology; Internal Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,958,902 | Treatment outcome of mucosa-associated lymphoid tissue/marginal zone non-Hodgkin's lymphoma. | International journal of radiation oncology, biology, physics | Int J Radiat Oncol Biol Phys | 52 | 4 | 10.1016/s0360-3016(01)02714-6 | eng | 2,002 | 3 | 15 | null | null | null | [PURPOSE] To evaluate the treatment outcome in patients with mucosa-associated lymphoid tissue (MALT)/marginal zone (MZ) non-Hodgkin's lymphoma (NHL). [MATERIALS AND METHODS] Between 1986 and 2000, 66 patients with clinical stage (CS) I-IV MALT/MZ NHL were treated; these comprise the study population. The progression-f... | null | 1.712 | 286 | Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging | Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy | 2,002 |
11,956,667 | Effect of a conserved mutation in uridine diphosphate glucuronosyltransferase 1A1 and 1A6 on glucuronidation of a metabolite of flutamide. | European journal of clinical pharmacology | Eur J Clin Pharmacol | 58 | 1 | 10.1007/s00228-001-0417-2 | eng | 2,002 | 4 | null | 2,002 | 2 | 16 | [OBJECTIVE] We investigated how the conserved mutation (Y486D) changed the kinetic parameters of uridine diphosphate glucuronosyltransferase 1A1 and 1A6 (UGT1A1 and 1A6) for 2-amino-5-nitro-4-trifluoromethylphenol, which is a major metabolite of flutamide, a nonsteroidal antiandrogenic agent. [METHODS] The wild-type or... | null | 0.622 | 126 | Medicine; Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,002 |
11,956,380 | Predictors of outcome in head injury: proposal of a new scaling system. | The Journal of trauma | J Trauma | 52 | 4 | 10.1097/00005373-200204000-00009 | eng | 2,002 | 4 | null | null | null | null | [BACKGROUND] In a statistical outcome analysis covering 10 years, 554 patients with isolated head trauma were analyzed. The aim of this study was to combine clinical and computed tomographic characteristics in a prognostic scoring system determining outcome after head injury. [METHODS] After collection of data, mortali... | null | null | null | null | null | null |
11,956,282 | Carcinoembryonic antigen as a target for therapeutic anticancer vaccines: a review. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology | J Clin Oncol | 20 | 8 | 10.1200/JCO.2002.08.017 | eng | 2,002 | 4 | 15 | null | null | null | [PURPOSE] To describe the features of carcinoembryonic antigen (CEA) that are important for its use in vaccination approaches and review the clinical experience with therapeutic vaccines targeting CEA. [METHODS] A PubMed search was performed on CEA, along with various qualifiers such as cancer vaccines, epitopes, and f... | null | 4.274 | 646 | Cancer Research; Medicine; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,954,987 | Isolation and characterization of Bacillus cereus-like bacteria from faecal samples from greenhouse workers who are using Bacillus thuringiensis-based insecticides. | International archives of occupational and environmental health | Int Arch Occup Environ Health | 75 | 3 | 10.1007/s00420-001-0293-1 | eng | 2,002 | 3 | null | null | null | null | [OBJECTIVES] Since the discovery of the insecticidal activity of Bacillus thuringiensis at the beginning of the twentieth century, this bacterium has been used increasingly against various insect pests. In spite of the extensive use of B. thuringiensis, only sporadic clinical case reports have been published. In recent... | null | 0.607 | 105 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
11,953,697 | Push enteroscopy in a UK district general hospital: experience of 51 cases over 2 years. | European journal of gastroenterology & hepatology | Eur J Gastroenterol Hepatol | 14 | 3 | 10.1097/00042737-200203000-00016 | eng | 2,002 | 3 | null | null | null | null | [OBJECTIVES] To determine the number of patients referred for enteroscopy in a district general hospital (DGH), the indication, enteroscopic +/- histological diagnosis, and to compare findings with other series from tertiary referral centres or outside the UK. [DESIGN] Retrospective case series over a 2-year period. [R... | null | null | null | null | null | null |
11,953,463 | Skeletal muscle mitochondrial function and exercise capacity in HIV-infected patients with lipodystrophy and elevated p-lactate levels. | AIDS (London, England) | AIDS | 16 | 7 | 10.1097/00002030-200205030-00003 | eng | 2,002 | 5 | 3 | null | null | null | [OBJECTIVE] To investigate the skeletal muscle mitochondrial function in HIV-infected patients with lipodystrophy or elevated p-lactate levels. [DESIGN] Eight HIV patients treated with highly active antiretroviral therapy, with lipodystrophy or elevated p-lactate, and eight healthy controls were exposed to incremental ... | null | 3.427 | 233 | Immunology; Immunology and Allergy; Infectious Diseases | Immunology and Microbiology; Medicine | 2,002 |
11,953,294 | ACGME requirements for end-of-life training in selected residency and fellowship programs: a status report. | Academic medicine : journal of the Association of American Medical Colleges | Acad Med | 77 | 4 | 10.1097/00001888-200204000-00008 | eng | 2,002 | 4 | null | null | null | null | [INTRODUCTION] National recommendations have been developed for physicians' end-of-life (EOL) education. No comprehensive assessment has been done to examine postgraduate (residency and fellowship) EOL training. [METHOD] The authors reviewed the EOL content for 46 specialties in postgraduate training programs that affe... | null | 0.78 | 199 | Education; Medicine | Medicine; Social Sciences | 2,002 |
11,952,647 | Facilitating factors and barriers to the implementation of intensive home-based behavioural intervention for young children with autism. | Child: care, health and development | Child Care Health Dev | 28 | 2 | 10.1046/j.1365-2214.2002.00251.x | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Although international interest in intensive home-based early behavioural intervention for children with autism is increasing, there is little or no published research on the experiences of families conducting these programmes. [METHODS] One hundred and forty-one UK parents conducting Lovaas-style interven... | null | 0.345 | 101 | Pediatrics, Perinatology and Child Health; Public Health, Environmental and Occupational Health; Developmental and Educational Psychology | Medicine; Psychology | 2,002 |
11,952,488 | Biochemical markers of the L-arginine-nitric oxide pathway in the aqueous humour in glaucoma patients. | Acta ophthalmologica Scandinavica | Acta Ophthalmol Scand | 80 | 2 | 10.1034/j.1600-0420.2002.800214.x | eng | 2,002 | 4 | null | null | null | null | [PURPOSE] To study the role of the L-arginine-nitric oxide (NO) pathway in aqueous humour dynamics by measuring nitrate, nitrite and cyclic (cGMP) levels in guanosine 3',5'-monophosphate the aqueous humour of glaucomatous and nonglaucomatous cataract patients. [METHODS] The study involved 38 glaucoma patients undergoin... | null | null | null | null | null | null |
11,952,291 | Early diagnosis of herpes zoster by polymerase chain reaction. | Journal of the European Academy of Dermatology and Venereology : JEADV | J Eur Acad Dermatol Venereol | 16 | 1 | 10.1046/j.0926-9959.2001.00351.x | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] Herpes zoster is a common disease caused by the varicella-zoster virus. The use of virostatic agents as early as possible is necessary in shortening zoster-associated pain. [OBJECTIVES] Rapid diagnosis is necessary for the optimal efficacy of antiviral therapy. The diagnosis in the early stage of infection... | null | 0.385 | 144 | Dermatology; Infectious Diseases | Medicine | 2,002 |
11,952,020 | Therapeutic drug monitoring of immunosuppressant drugs in clinical practice. | Clinical therapeutics | Clin Ther | 24 | 3 | 10.1016/s0149-2918(02)85038-x | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Therapeutic drug monitoring (TDM) is essential to maintain the efficacy of many immunosuppressant drugs while minimizing their toxicity. TDM has become more refined with the development of new monitoring techniques and more specific assays. [OBJECTIVE] This article summarizes current data on TDM of the fol... | null | 1.038 | 153 | Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,002 |
11,950,028 | Serum and synovial fluid concentrations of matrix metalloproteinases 3 and its tissue inhibitor 1 in juvenile idiopathic arthritides. | The Journal of rheumatology | J Rheumatol | 29 | 4 | null | eng | 2,002 | 4 | null | null | null | null | [OBJECTIVE] Matrix metalloproteinases (MMP) are a large family of proteolytic enzymes involved in the remodeling of extracellular matrix during tissue resorption in idiopathic arthritides. We investigated serum and synovial fluid (SF) concentrations of MMP-3 and its tissue inhibitor (TIMP-1) in juvenile idiopathic arth... | null | 1.022 | 201 | Rheumatology; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,002 |
11,950,018 | Risk factors for the development of psoriatic arthritis: a population based nested case control study. | The Journal of rheumatology | J Rheumatol | 29 | 4 | null | eng | 2,002 | 4 | null | null | null | null | [OBJECTIVE] To identify factors influencing the development of psoriatic arthritis (PsA) in a population-based, inception cohort of psoriasis (PS) patients. [METHODS] Using the population-based data resources of the Rochester Epidemiology Project. which ensures virtually complete ascertainment of all clinically defined... | null | 1.022 | 201 | Rheumatology; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,002 |
11,950,012 | Subclinical myositis is common in primary Sjögren's syndrome and is not related to muscle pain. | The Journal of rheumatology | J Rheumatol | 29 | 4 | null | eng | 2,002 | 4 | null | null | null | null | [OBJECTIVE] Although muscle pain is common in primary Sjögren's syndrome (SS), the underlying mechanisms are mainly unknown. We studied all patients with SS at our rheumatology unit with respect to muscle pain in general and to fibromyalgia (FM), and correlated clinical data to muscle biopsy findings. [METHODS] We inve... | null | 1.022 | 201 | Rheumatology; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,002 |
11,949,920 | Development of a scale to measure patients' trust in health insurers. | Health services research | Health Serv Res | 37 | 1 | null | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVE] To develop a scale to measure patients' trust in health insurers, including public and private insurers and both indemnity and managed care. A scale was developed based on our conceptual model of insurer trust. The scale was analyzed for its factor structure, internal consistency, construct validity, and ot... | null | 1.722 | 149 | Health Policy | Medicine | 2,002 |
11,949,747 | Surgical bypass for subclavian vein occlusion in hemodialysis patients. | Journal of the American College of Surgeons | J Am Coll Surg | 194 | 4 | 10.1016/s1072-7515(02)01127-4 | eng | 2,002 | 4 | null | null | null | null | [BACKGROUND] The majority of patients with end-stage renal disease are dependent on hemodialysis. Significant stenosis or occlusion of the subclavian vein is known to occur in 20% to 50% of patients who have had central venous catheters inserted into the subclavian vein or the internal jugular vein. Surgical bypass of ... | null | 1.273 | 212 | Surgery | Medicine | 2,002 |
11,949,746 | Removal of chest tubes in children without water seal after elective thoracic procedures: a randomized prospective study. | Journal of the American College of Surgeons | J Am Coll Surg | 194 | 4 | 10.1016/s1072-7515(02)01113-4 | eng | 2,002 | 4 | null | null | null | null | [BACKGROUND] Chest tubes are often placed in children after elective thoracic surgical procedures. Depending on surgeon preference, tubes can be pulled directly from suction or after a trial of water seal. Removal of the tube without water seal potentially allows earlier removal, decreased postoperative pain, and earli... | null | 1.273 | 212 | Surgery | Medicine | 2,002 |
11,949,738 | Symptom differences between older depressed primary care patients with and without history of trauma. | International journal of psychiatry in medicine | Int J Psychiatry Med | 31 | 4 | 10.2190/61ME-F2M0-3PH5-G59E | eng | 2,001 | null | null | null | null | null | [OBJECTIVE] The current study explored the relationship between past traumatic experiences and current depression in a sample of depressed older adult primary care patients. [METHOD] Sixty-six patients were referred from primary care to a psychogeriatric clinic that specialized in the treatment of unipolar depressive d... | null | null | null | null | null | null |
11,948,115 | Expression of the breast cancer resistance protein in breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research | Clin Cancer Res | 8 | 4 | null | eng | 2,002 | 4 | null | null | null | null | [PURPOSE] The breast cancer resistance protein (BCRP) is involved in in vitro multidrug resistance and was first identified in the breast cancer cell line MCF7/AdrVp. The aim of this study was to investigate the role of BCRP in resistance of breast cancer to anthracycline treatment. [EXPERIMENTAL DESIGN] BCRP mRNA was ... | null | 2.452 | 392 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,948,034 | Megestrol acetate stimulates weight gain and ventilation in underweight COPD patients. | Chest | Chest | 121 | 4 | 10.1378/chest.121.4.1070 | eng | 2,002 | 4 | null | null | null | null | [STUDY OBJECTIVES] To assess the effect of megestrol acetate (MA), a progestational appetite stimulant commonly used in patients with AIDS and cancer, on body weight and composition, respiratory muscle strength, arterial blood gas levels, and subjective perceptions in COPD patients. [DESIGN AND SETTING] Prospective, do... | null | 1.171 | 337 | Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,002 |
11,948,033 | Comparison of the efficacy, tolerability, and safety of formoterol dry powder and oral, slow-release theophylline in the treatment of COPD. | Chest | Chest | 121 | 4 | 10.1378/chest.121.4.1058 | eng | 2,002 | 4 | null | null | null | null | [STUDY OBJECTIVE] To compare the efficacy, tolerability, and safety of therapy with formoterol and oral slow-release theophylline (THEO) in patients with COPD. [DESIGN] A randomized, parallel-group study, with double-blind arms for formoterol and placebo (PL) and an open arm for oral slow-release THEO administered in i... | null | 1.171 | 337 | Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,002 |
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