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11,782,290 | Manipulation of gene expression by an ecdysone-inducible gene switch in tumor xenografts. | BMC biotechnology | BMC Biotechnol | 1 | null | 10.1186/1472-6750-1-11 | eng | 2,001 | null | null | 2,001 | 12 | 18 | [BACKGROUND] Rapid, robust and reversible induction of transgene expression would significantly facilitate cancer gene therapy as well as allow the in vivo functional study of newly discovered genes in tumor formation and progression. The popularity of the ecdysone inducible gene switch system has led us to investigate... | null | null | 99 | Biotechnology | Biochemistry, Genetics and Molecular Biology | 2,001 |
11,781,542 | The effect of light regimen and melatonin on the development of spontaneous mammary tumors in HER-2/neu transgenic mice is related to a downregulation of HER-2/neu gene expression. | Neuro endocrinology letters | Neuro Endocrinol Lett | 22 | 6 | null | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVES AND DESIGN] The effect and the mechanism of light regimen and melatonin on the development of mammary tumors in HER2/neu transgenic mice were investigated. Female HER-2/neu mice starting from the age of 2 months were kept under standard light/dark regimen (LD) or constant light illumination (LL) and a part ... | null | null | null | null | null | null |
11,781,292 | Sodium current in human jejunal circular smooth muscle cells. | Gastroenterology | Gastroenterology | 122 | 1 | 10.1053/gast.2002.30346 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND AND AIMS] Sodium channels are key regulators of neuronal and muscle excitability. However, sodium channels have not been definitively identified in gastrointestinal smooth muscle. The aim of the present study was to determine if a Na(+) current is present in human jejunal circular smooth muscle cells. [METH... | null | 3.536 | 482 | Gastroenterology | Medicine | 2,002 |
11,781,281 | Oncogenic beta-catenin and MMP-7 (matrilysin) cosegregate in late-stage clinical colon cancer. | Gastroenterology | Gastroenterology | 122 | 1 | 10.1053/gast.2002.30306 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND AND AIMS] Recent in vitro studies showed that beta-catenin translocated into the tumor cell nucleus functions as an oncogene by transactivating oncogenes, including MMP-7. We conducted a large-scale analysis of beta-catenin and MMP-7 expression in human colon cancer to determine the potential clinical impor... | null | 3.536 | 482 | Gastroenterology | Medicine | 2,002 |
11,780,902 | Transplantation of human fetal brain cells into ischemic lesions of adult gerbil hippocampus. | Journal of neurosurgery | J Neurosurg | 95 | 2 | 10.3171/jns.2001.95.2.0308 | eng | 2,001 | 8 | null | null | null | null | [OBJECT] The goal of this study was to establish whether transplanted cells derived from fetal human brain can survive in an ischemic lesion. [METHODS] Sixteen adult male Mongolian gerbils underwent transient bilateral common carotid artery occlusion. One week later, cell suspensions prepared from fetal human brain wer... | null | 1.482 | 244 | Neurology; Surgery | Medicine | 2,001 |
11,780,886 | A multidisciplinary team approach to skull base chondrosarcomas. | Journal of neurosurgery | J Neurosurg | 95 | 2 | 10.3171/jns.2001.95.2.0184 | eng | 2,001 | 8 | null | null | null | null | [OBJECT] The authors review their experience with treating skull base chondrosarcomas, which are much rarer than skull base chordomas and differ from them in prognosis and treatment. [METHODS] Seventeen patients (12 male and five female patients) with histologically verified chondrosarcomas were followed up prospective... | null | 1.482 | 244 | Neurology; Surgery | Medicine | 2,001 |
11,780,447 | Nested polymerase chain reaction in detection of Plasmodium vivax sporozoites in mosquitoes. | Chinese medical journal | Chin Med J (Engl) | 114 | 6 | null | eng | 2,001 | 6 | null | null | null | null | [OBJECTIVE] To detect malaria DNA in mosquitoes. [METHODS] A nested polymerase chain reaction (nested PCR) procedure which amplifies a 121 bp DNA of a SSUrRNA gene specific to Plasmodium vivax was used. [RESULTS] In laboratory-infected mosquitoes, nested PCR could detect as few as 3 sporozoites or 1 infected mosquito m... | null | 0.127 | 84 | Medicine | Medicine | 2,001 |
11,780,422 | Diagnosis and treatment of bronchial rupture from blunt thoracic trauma. | Chinese medical journal | Chin Med J (Engl) | 114 | 5 | null | eng | 2,001 | 5 | null | null | null | null | [OBJECTIVE] To evaluate the diagnosis and management of bronchial rutpture from blunt thoracic trauma. [METHODS] A group of 31 patients with bronchial rupture was involved. Chest roentgenography, tomography and bronchoscopy were performed on all patients. The surgical technique and complications were described. [RESULT... | null | 0.127 | 84 | Medicine | Medicine | 2,001 |
11,780,362 | Construction of a recombinant plasmid harbouring the rhoptry protein 1 gene of Toxoplasma gondii and preliminary observations on DNA immunity. | Chinese medical journal | Chin Med J (Engl) | 114 | 8 | null | eng | 2,001 | 8 | null | null | null | null | [OBJECTIVE] To observe the immune responses elicited in BALB/c mice by a DNA vaccine. A gene encoding rhoptry protein 1 (ROP1) from Toxoplasma gondii (T. gondii) was cloned into vector pcDNA3. [METHODS] Amplifyied gene fragments coding for ROP1 from the genomic DNA of T. gondii ZS2 were inserted into cloning vector, pU... | null | 0.127 | 84 | Medicine | Medicine | 2,001 |
11,780,347 | Pathogen of root surface caries in the elderly. | Chinese medical journal | Chin Med J (Engl) | 114 | 7 | null | eng | 2,001 | 7 | null | null | null | null | [OBJECTIVE] To study the pathogen of root surface caries in the elderly. [METHODS] Plaque samples from the experimental group and the control group were collected. After culturing in selective and non-selective media, the different bacteria were isolated. The counts and the positive rates of total bacteria, porphyromon... | null | 0.127 | 84 | Medicine | Medicine | 2,001 |
11,780,318 | Primary studies on heroin abuse and injury induced by oxidation and lipoperoxidation. | Chinese medical journal | Chin Med J (Engl) | 114 | 3 | null | eng | 2,001 | 3 | null | null | null | null | [OBJECTIVE] To further reveal serious risks of heroin abuse to human body and clarify grave injuries of oxidation, peroxidation and lipoperoxidation induced by nitric oxide and other free radicals to heroin abusers. [METHODS] Determined and compared plasma levels of nitric oxide (P-NO), vitamin C (P-VC), vitamin E (P-V... | null | 0.127 | 84 | Medicine | Medicine | 2,001 |
11,779,758 | Heat shock protein 70 gene polymorphisms in Mexican patients with spondyloarthropathies. | Annals of the rheumatic diseases | Ann Rheum Dis | 61 | 1 | 10.1136/ard.61.1.48 | eng | 2,002 | 1 | null | null | null | null | [OBJECTIVE] To investigate the role of HSP70 genes as contributors to genetic susceptibility of the spondyloarthropathies (SpA) in the Mexican population. [METHODS] The study included 150 patients with SpA (undifferentiated spondyloarthropathy (uSpA) 68, ankylosing spondylitis (AS) 60, and reactive arthritis 22) and 15... | null | 1.164 | 300 | Biochemistry, Genetics and Molecular Biology; Immunology and Allergy; Rheumatology; Immunology | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,002 |
11,779,438 | 192Ir endovascular irradiation prevents restenosis after balloon angioplasty in rabbit. | Chinese medical journal | Chin Med J (Engl) | 114 | 1 | null | eng | 2,001 | 1 | null | null | null | null | [OBJECTIVE] To examine the effect of endovascular irradiation on restenosis after balloon angioplasty in rabbit. [METHODS] After the establishment of rabbit iliac atherosclerosis model, balloon angioplasty was performed at the lesion segment of the iliac artery. Rabbits were randomly divided into three groups: control ... | null | 0.127 | 84 | Medicine | Medicine | 2,001 |
11,778,855 | Nightguard vital bleaching: a long-term study on efficacy, shade retention. side effects, and patients' perceptions. | Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] | J Esthet Restor Dent | 13 | 6 | 10.1111/j.1708-8240.2001.tb01021.x | eng | 2,001 | null | null | null | null | null | [BACKGROUND] The scientific literature is lacking in long-term clinical data on the duration of efficacy and post-treatment side effects of nightguard vital bleaching. [PURPOSE] This longitudinal clinical study was undertaken (1) to determine the clinical efficacy and duration of efficacy at 3, 6, and 47 months post tr... | null | 0.292 | 79 | Dentistry | Dentistry | 2,001 |
11,777,520 | Effect of antenatal and postnatal corticosteroid therapy on weight gain and head circumference growth in the nursery. | Obstetrics and gynecology | Obstet Gynecol | 99 | 1 | 10.1016/s0029-7844(01)01657-x | eng | 2,002 | 1 | null | null | null | null | [OBJECTIVE] To assess the effect of antenatal and postnatal corticosteroids on head circumference growth and weight gain from birth to discharge. [METHODS] We conducted a retrospective analysis of nonanomalous newborns admitted to the neonatal intensive care unit from 23 to 34 6/7 weeks of gestation. Independent variab... | null | 1.319 | 268 | Obstetrics and Gynecology | Medicine | 2,002 |
11,776,131 | Antigenic variation and cytoadherence of PfEMP1 of Plasmodium falciparum-infected erythrocyte from malaria patients. | Chinese medical journal | Chin Med J (Engl) | 113 | 11 | null | eng | 2,000 | 11 | null | null | null | null | [OBJECTIVE] To approve a theoretical basis for the molecular pathogenesis of human cerebral malaria and treatment with prevention. [METHODS] The blood samples were collected from 24 patients with cerebral malaria, 143 with falciparum malaria, 34 with vivax malaria and 20 healthy controls from the endemic areas of Yunna... | null | 0.143 | 84 | Medicine | Medicine | 2,000 |
11,775,960 | Interaction of [D-Trp6, Des-Gly10] LHRH ethylamide and hydroxy propyl beta-cyclodextrin (HPbetaCD): thermodynamics of interaction and protection from degradation by alpha-chymotrypsin. | Pharmaceutical development and technology | Pharm Dev Technol | 6 | 4 | 10.1081/pdt-120000297 | eng | 2,001 | 11 | null | null | null | null | [PURPOSE] The purpose of this study is to investigate the mechanisms and thermodynamics of the interaction between hydroxypropyl beta-cyclodextrin (HPdetaCD) and [D-Trp6, des-Gly10] LHRH ethylamide (deslorelin), a peptide drug. [METHODS] We used UV and fluorescence spectroscopy to study the interaction of HPbetaCD and ... | null | 0.548 | 74 | Medicine; Pharmaceutical Science | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,001 |
11,775,215 | Neuroendocrine differentiation in ovarian mucinous tumors. | Chinese medical journal | Chin Med J (Engl) | 113 | 1 | null | eng | 2,000 | 1 | null | null | null | null | [OBJECTIVE] To investigate the relationship between neuroendocrine differentiation in ovarian mucinous tumors and its genesis. [METHODS] A morphologic study of seventy-three cases of ovarian mucinous tumors (32 benign, 20 borderline, 21 malignant) using immunohistochemical and immunohistochemical/histochemical double s... | null | 0.143 | 84 | Medicine | Medicine | 2,000 |
11,773,851 | Menière's disease in the elderly. | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology | Otol Neurotol | 23 | 1 | 10.1097/00129492-200201000-00017 | eng | 2,002 | 1 | null | null | null | null | [OBJECTIVES] To assess the prevalence, presentation, treatment, and evolution of Menière's disease in elderly patients (> or = 65 yr old). [STUDY DESIGN] Retrospective clinical study and case report. [SETTING] A neuro-otology referral center at the university hospital in Bern, Switzerland, and a neurotologic practice i... | null | null | null | null | null | null |
11,773,843 | Cochleosaccular pathology after perinatal and postnatal asphyxia: histopathologic findings. | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology | Otol Neurotol | 23 | 1 | 10.1097/00129492-200201000-00009 | eng | 2,002 | 1 | null | null | null | null | [OBJECTIVE] This study describes the histopathologic findings of a patient with severe bilateral sensorineural hearing loss after perinatal and postnatal hypoxia and asphyxia. [STUDY DESIGN] Histopathologic examination on the temporal bones. [SETTING] The study was performed at the Elizabeth McCullough Knowles Otopatho... | null | null | null | null | null | null |
11,773,165 | Phase II study of oral capecitabine in patients with advanced or metastatic pancreatic cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology | J Clin Oncol | 20 | 1 | 10.1200/JCO.2002.20.1.160 | eng | 2,002 | 1 | 1 | null | null | null | [PURPOSE] To determine the safety and efficacy of capecitabine (Xeloda; Roche Laboratories, Nutley, NJ) in patients with metastatic or unresectable, locally advanced pancreatic cancer. [PATIENTS AND METHODS] Forty-two patients were treated with oral capecitabine 1,250 mg/m(2) administered twice daily (2,500 mg/m(2)/d) ... | null | 4.274 | 646 | Cancer Research; Medicine; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,772,968 | Interventional study of high dose folic acid in gastric carcinogenesis in beagles. | Gut | Gut | 50 | 1 | 10.1136/gut.50.1.61 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] A decrease in folic acid and subsequent DNA hypomethylation may be involved in gastric carcinogenesis. Epidemiological and nutritional studies have indicated that folate status modulates the risk of developing cancers. [AIMS] To investigate whether folic acid plays an important role in the chemoprevention ... | null | 2.104 | 364 | Gastroenterology | Medicine | 2,002 |
11,772,762 | Population attributable fractions of psychiatric disorders and behavioral outcomes associated with combat exposure among US men. | American journal of public health | Am J Public Health | 92 | 1 | 10.2105/ajph.92.1.59 | eng | 2,002 | 1 | null | null | null | null | [OBJECTIVES] This study determined the percentage of adverse outcomes in US men attributable to combat exposure. [METHODS] Standardized psychiatric interviews (modified Diagnostic Interview Schedule and Composite International Diagnostic Interview assessments) were administered to a representative national sample of 25... | null | 2.167 | 321 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
11,872,077 | Frequency and prognostic relevance of cyclin D1 dysregulation in multiple myeloma. | European journal of haematology | Eur J Haematol | 67 | 5-6 | 10.1034/j.1600-0609.2001.00559.x | eng | 2,001 | null | null | null | null | null | [OBJECTIVE] Cyclin D1 dysregulation has been found with varying frequencies in multiple myeloma (MM) and has been suggested to be associated with a poor prognosis. The aim of this study was to investigate the frequency of cyclin D1 dysregulation in patients being treated for MM and to test whether cyclin D1 dysregulati... | null | 0.52 | 99 | Medicine; Hematology | Medicine | 2,001 |
11,871,626 | Factors associated with nurses' poor knowledge and practice of transfusion safety procedures in Aquitaine, France. | International journal for quality in health care : journal of the International Society for Quality in Health Care | Int J Qual Health Care | 14 | 1 | 10.1093/intqhc/14.1.25 | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVES] To (1) describe knowledge, attitudes, and reported practice of blood transfusion of nurses in Aquitaine's hospitals; (2) measure the potential threat for patient safety of poor transfusion-related knowledge and practice; and (3) identify factors associated with poor knowledge and practice. [DESIGN] Survey ... | null | 0.539 | 113 | Health Policy; Medicine; Public Health, Environmental and Occupational Health | Medicine | 2,002 |
11,870,786 | Facial resurfacing in patients with Fitzpatrick skin type IV. | Lasers in surgery and medicine | Lasers Surg Med | 30 | 2 | 10.1002/lsm.10012 | eng | 2,002 | null | null | null | null | null | [BACKGROUND AND OBJECTIVES] Though post-inflammatory hyperpigmentation (PIH) is probably the most common complication of laser resurfacing and appears to correlate directly with the intensity of the patient's natural pigmentation, there is very little data that specifically addresses the risks of dyspigmentation in mor... | null | 0.865 | 130 | Dermatology; Surgery | Medicine | 2,002 |
11,870,169 | T-cell/histiocyte-rich large B-cell lymphoma: a distinct clinicopathologic entity. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology | J Clin Oncol | 20 | 5 | 10.1200/JCO.2002.20.5.1269 | eng | 2,002 | 3 | 1 | null | null | null | [PURPOSE] Although it has proven difficult to delineate diagnostically reproducible and clinically relevant subgroups, the heterogeneity of diffuse large B-cell lymphomas (DLBCL) is widely acknowledged. In 1992, we reported on six cases that suggested that large B-cell lymphoma rich in stromal histiocytes and T cells m... | null | 4.274 | 646 | Cancer Research; Medicine; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,870,101 | Immediate post-partum insertion of intrauterine devices: a Cochrane review. | Human reproduction (Oxford, England) | Hum Reprod | 17 | 3 | 10.1093/humrep/17.3.549 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Insertion of an intrauterine device (IUD) immediately after delivery is appealing for several reasons. The woman is known not to be pregnant, her motivation for contraception may be high and the setting may be convenient for both the woman and her provider. However, the risk of spontaneous expulsion may be... | null | 1.501 | 264 | Obstetrics and Gynecology; Rehabilitation; Reproductive Medicine | Medicine | 2,002 |
11,870,006 | Higher expression of serotonin 5-HT(2A) receptors in the postmortem brains of teenage suicide victims. | The American journal of psychiatry | Am J Psychiatry | 159 | 3 | 10.1176/appi.ajp.159.3.419 | eng | 2,002 | 3 | null | null | null | null | [OBJECTIVE] Abnormalities of serotonin (5-HT) receptor subtypes have been observed in the postmortem brains of adult suicide victims; however, their role in teenage suicide is unexplored. The authors examined whether 5-HT(2A) receptor subtypes are altered in the postmortem brains of teenage suicide victims. [METHOD] Le... | null | 4.207 | 405 | Psychiatry and Mental Health | Medicine | 2,002 |
11,869,761 | Are antidepressants less effective in the acute treatment of bipolar I compared to unipolar depression? | Journal of affective disorders | J Affect Disord | 67 | 1-3 | 10.1016/s0165-0327(01)00449-9 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] Using our routine documentation system we evaluated the hypothesis that antidepressants may be less effective in the acute treatment of bipolar I depressed patients compared to unipolar depressed patients. [METHOD] Based on the data from 2032 consecutively admitted inpatients with unipolar or bipolar I dep... | null | 1.347 | 245 | Clinical Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,001 |
11,869,306 | The effect of subclinical hypothyroidism on metabolic control in children and adolescents with Type 1 diabetes mellitus. | Diabetic medicine : a journal of the British Diabetic Association | Diabet Med | 19 | 1 | 10.1046/j.1464-5491.2002.00635.x | eng | 2,002 | 1 | null | null | null | null | [AIMS] Associated autoimmune phenomena might influence metabolic control in children and adolescents with Type 1 diabetes mellitus. A retrospective case control study was performed in order to explore the effect of subclinical hypothyroidism on metabolic control in Type 1 diabetes mellitus. [PATIENTS AND METHODS] For t... | null | 0.999 | 171 | Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,869,297 | Patient-assessed health outcome measures for diabetes: a structured review. | Diabetic medicine : a journal of the British Diabetic Association | Diabet Med | 19 | 1 | 10.1046/j.1464-5491.2002.00650.x | eng | 2,002 | 1 | null | null | null | null | [AIMS] To identify available disease-specific measures of health-related quality of life (HRQL) for diabetes and to review evidence for the reliability, validity and responsiveness of instruments. [METHODS] Systematic searches were used to identify instruments. Instruments were assessed against predefined inclusion and... | null | 0.999 | 171 | Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,869,073 | Expression of beta1 integrins during periosteal chondrogenesis. | Osteoarthritis and cartilage | Osteoarthritis Cartilage | 10 | 2 | 10.1053/joca.2001.0490 | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVE] The interactions between integrins and extracellular matrix proteins are known to modulate cell behavior, and may be involved in regulating cartilage formation and repair. The purpose of this study was to determine the patterns and localization of expression of the beta1 integrins during cartilage formation... | null | 0.99 | 197 | Biomedical Engineering; Orthopedics and Sports Medicine; Rheumatology | Engineering; Medicine | 2,002 |
11,868,064 | Myocardial function and geometry in hypertensive subjects with low levels of afterload. | American heart journal | Am Heart J | 143 | 3 | 10.1067/mhj.2002.119764 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] It has been hypothesized that the level of end-systolic wall stress (sigma(m)) is a feedback signal that regulates the level of hypertrophy. Thus, low levels of sigma(m) may signify inappropriate hypertrophy. [METHODS] To characterize left ventricular (LV) structure and systolic function in hypertensive su... | null | 1.614 | 211 | Cardiology and Cardiovascular Medicine | Medicine | 2,002 |
11,868,007 | Epinephrine versus epinephrine plus fibrin glue injection in peptic ulcer bleeding: a prospective randomized trial. | Gastrointestinal endoscopy | Gastrointest Endosc | 55 | 3 | 10.1067/mge.2002.121875 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Peptic ulcer bleeding remains a disease with considerable morbidity and mortality. Epinephrine is the most widely used endoscopic injection agent, but bleeding recurs in 20% of high-risk cases. Fibrin glue might be an ideal injection agent, based on its physiologic properties, despite its demanding injecti... | null | 1.023 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,002 |
11,867,948 | Changes in Mac-1 and CD14 expression on monocytes and serum soluble CD14 level during push/pull hemodiafiltration. | Nephron | Nephron | 90 | 3 | 10.1159/000049063 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND/AIM] Employment of treated dialysate as replacement fluid raises concerns about exposure of patients to pyrogenic substances. This study was undertaken to evaluate the safety of treated dialysate as the replacement fluid for push/pull hemodiafiltration. [METHODS] In the present study, changes in the express... | null | 0.526 | 102 | Medicine; Nephrology; Urology; Physiology; Physiology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,867,793 | Unilateral transpedicular percutaneous vertebroplasty: initial experience. | Radiology | Radiology | 222 | 3 | 10.1148/radiol.2223010718 | eng | 2,002 | 3 | null | null | null | null | [PURPOSE] To compare the radiographic and clinical outcomes of a unipediculate approach with those of standard bipediculate vertebroplasty. [MATERIALS AND METHODS] Retrospective review of percutaneous vertebroplasties yielded 18 vertebrae in 17 patients that were treated with a standard bipediculate approach and 57 ver... | null | 2.476 | 346 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,002 |
11,866,322 | Categoric overgeneral autobiographical memory in adolescents with major depressive disorder. | Psychological medicine | Psychol Med | 32 | 2 | 10.1017/s0033291701005189 | eng | 2,002 | 2 | null | null | null | null | [BACKGROUND] Categoric, overgeneral autobiographical memory is more common in depressed adults than controls and predicts persistence of depression. This cross-sectional study investigated whether, compared with non-depressed psychiatric cases and community controls, first episode major depressive disorder (MDD) in ado... | null | 2.44 | 251 | Applied Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,002 |
11,866,284 | The effect of high dose and short interval HBV vaccination in individuals with chronic hepatitis C. | The American journal of gastroenterology | Am J Gastroenterol | 97 | 2 | 10.1111/j.1572-0241.2002.05482.x | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVES] The efficacy of the standard hepatitis B virus (HBV) vaccination schedule in individuals with chronic hepatitis C is reported to be reduced. Our aim was to assess the response rate to high dose, short interval HBV vaccination in such individuals. [METHODS] A total of 152 individuals with chronic hepatitis ... | null | 1.416 | 296 | Gastroenterology; Hepatology | Medicine | 2,002 |
11,866,269 | Yield of colonoscopy in patients with nonacute rectal bleeding: a multicenter database study of 1766 patients. | The American journal of gastroenterology | Am J Gastroenterol | 97 | 2 | 10.1111/j.1572-0241.2002.05465.x | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVE] There are few data to guide the choice between colonoscopy and flexible sigmoidoscopy in patients with nonacute rectal bleeding, especially in younger age groups. Our aim was to determine the yield of colonoscopy for significant proximal large bowel disease in the absence of significant distal disease, with... | null | 1.416 | 296 | Gastroenterology; Hepatology | Medicine | 2,002 |
11,865,084 | Administration of FR167653, a new anti-inflammatory compound, prevents renal ischaemia/reperfusion injury in mice. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association | Nephrol Dial Transplant | 17 | 3 | 10.1093/ndt/17.3.399 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Various types of chemokines/cytokines play important roles in ischaemia/reperfusion injury in kidneys. However, the roles of p38 mitogen-activated protein kinase (MAPK) in the inflammatory processes of renal ischaemia/reperfusion injury remain to be investigated. We explored the effect of FR167653, a speci... | null | 0.833 | 203 | Medicine; Nephrology; Transplantation | Medicine | 2,002 |
11,864,881 | Biotypes and serotypes of Haemophilus influenzae ocular isolates. | The British journal of ophthalmology | Br J Ophthalmol | 86 | 3 | 10.1136/bjo.86.3.276 | eng | 2,002 | 3 | null | null | null | null | [AIM] To determine which subtypes of Haemophilus influenzae are most commonly associated with ocular disease, and whether the site of ocular H influenzae infection is correlated with specific subtypes of the organism. [METHODS] The biotypes and serotypes of ocular H influenzae isolates collected at the Francis I Procto... | null | 1.259 | 185 | Ophthalmology; Sensory Systems; Cellular and Molecular Neuroscience | Medicine; Neuroscience | 2,002 |
11,864,675 | Antepartum, intrapartum, and neonatal significance of exercise on healthy low-risk pregnant working women. | Obstetrics and gynecology | Obstet Gynecol | 99 | 3 | 10.1016/s0029-7844(01)01754-9 | eng | 2,002 | 3 | null | null | null | null | [OBJECTIVE] To evaluate the influence of exercise on maternal and perinatal outcome in a low-risk healthy obstetric population. [METHODS] We conducted a prospective observational study of low-risk healthy women exercising during their pregnancy. An extensive questionnaire collected antepartum, intrapartum, and postpart... | null | 1.319 | 268 | Obstetrics and Gynecology | Medicine | 2,002 |
11,863,105 | A systematic review of the role of pulmonary irradiation in the management of primary bone tumours. | Annals of oncology : official journal of the European Society for Medical Oncology | Ann Oncol | 13 | 1 | 10.1093/annonc/mdf047 | eng | 2,002 | 1 | null | null | null | null | [INTRODUCTION] Adjuvant therapy in osteosarcoma (OS) and Ewing's sarcoma (ES) is primarily directed towards treatment of subclinical lung disease. Before the advent of modern intensive chemotherapy, lung irradiation was the only available adjuvant treatment. It has proven biological activity and low morbidity. There is... | null | 1.073 | 311 | Hematology; Medicine; Oncology | Medicine | 2,002 |
11,862,437 | Neurosurgical treatment of meningiomas in children and young adults. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery | Childs Nerv Syst | 17 | 12 | 10.1007/s00381-001-0516-5 | eng | 2,001 | 12 | null | 2,001 | 11 | 16 | [OBJECT] We studied the frequency, functional outcome, association with neurofibromatosis (NF) and relapse in patients operated on for meningiomas at age 0-20 years in three Norwegian centers between 1972 and 1999. [METHODS] Information was collected by examining case notes and histology records, conducting telephone i... | null | 0.543 | 100 | Medicine; Neurology; Pediatrics, Perinatology and Child Health | Medicine | 2,001 |
11,861,348 | Perioperative use of transesophageal echocardiography by anesthesiologists: impact in noncardiac surgery and in the intensive care unit. | Canadian journal of anaesthesia = Journal canadien d'anesthesie | Can J Anaesth | 49 | 3 | 10.1007/BF03020529 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] The American Society of Anesthesiologists (ASA) has published practice guidelines for the use of perioperative transesophageal echocardiography (TEE) but the role and impact of TEE performed by anesthesiologists outside the cardiac operating room (OR) is still poorly explored. We report our experience in t... | null | null | null | null | null | null |
11,861,240 | Risk adjusted mortality of critical illness in a defined geographical region. | Archives of disease in childhood | Arch Dis Child | 86 | 3 | 10.1136/adc.86.3.194 | eng | 2,002 | 3 | null | null | null | null | [AIMS] To evaluate the performance of the Paediatric Risk of Mortality (PRISM) score in a population of UK children and to use this score to examine severity of illness adjusted mortality of critically ill children <16 years old in a defined geographical region. [METHODS] Observational study of a defined population of ... | null | 0.959 | 169 | Pediatrics, Perinatology and Child Health | Medicine | 2,002 |
11,860,983 | Foveal hypoplasia in oculocutaneous albinism demonstrated by optical coherence tomography. | American journal of ophthalmology | Am J Ophthalmol | 133 | 3 | 10.1016/s0002-9394(01)01326-5 | eng | 2,002 | 3 | null | null | null | null | [PURPOSE] To document, in vivo, the foveal morphology and thickness in a patient with oculocutaneous albinism. [METHODS] Observational case report. In a 10-year-old female with oculocutaneous albinism, multiple cross-sectional scans of the fovea were performed using optical coherence tomography. [RESULTS] Optical coher... | null | 1.784 | 221 | Ophthalmology | Medicine | 2,002 |
11,860,970 | Balloon catheter dilation for treatment of persistent nasolacrimal duct obstruction. | American journal of ophthalmology | Am J Ophthalmol | 133 | 3 | 10.1016/s0002-9394(01)01403-9 | eng | 2,002 | 3 | null | null | null | null | [PURPOSE] To report the outcome of balloon catheter dilation of the lacrimal duct for treatment of children with persistent nasolacrimal duct obstruction after previous surgery. [DESIGN] Interventional case series. [METHODS] Thirty-two consecutive children with a history of persistent nasolacrimal duct obstruction foll... | null | 1.784 | 221 | Ophthalmology | Medicine | 2,002 |
11,860,405 | Effects of 5-HT(3) antagonism on postprandial gastric volume and symptoms in humans. | Alimentary pharmacology & therapeutics | Aliment Pharmacol Ther | 16 | 2 | 10.1046/j.1365-2036.2002.01144.x | eng | 2,002 | 2 | null | null | null | null | [BACKGROUND] Alosetron reduces symptoms of dyspepsia, but the physiological basis for the symptomatic benefit is unclear. [AIM] To assess 5-HT3 antagonism on postprandial gastric volume and symptoms after ingestion of maximum tolerable volume of a liquid meal. [METHODS] In 36 healthy volunteers, we assessed effects of ... | null | null | null | null | null | null |
11,859,871 | Involvement of breast epithelial-stromal interactions in the regulation of protein tyrosine phosphatase-gamma (PTPgamma) mRNA expression by estrogenically active agents. | Breast cancer research and treatment | Breast Cancer Res Treat | 71 | 1 | 10.1023/a:1013343718942 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] Protein tyrosine phosphatase gamma (PTPgamma) has been implicated as a tumor suppressor gene in kidney and lung cancers. Our previous results indicate that estradiol-17beta (E2)-induced suppression of PTPgamma may play a role in mammary tumorigenesis. Zeranol (Z), a nonsteroidal growth promoter with estrog... | null | 0.645 | 184 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
11,859,291 | An open-label study to evaluate the safety, tolerability and efficacy of rivastigmine in patients with mild to moderate probable Alzheimer's disease in the community setting. | Medical science monitor : international medical journal of experimental and clinical research | Med Sci Monit | 8 | 2 | null | eng | 2,002 | 2 | null | null | null | null | [BACKGROUND] Long-term safety and efficacy of Exelon (rivastigmine) was evaluated in a multi-center open-label study of 62 patients with probable mild to moderate Alzheimer's disease living in community setting. [MATERIAL/METHODS] The patients started treatment with 1.5 mg bid (3 mg/day) Exelon and were scheduled to re... | null | 0.186 | 107 | Medicine | Medicine | 2,002 |
11,858,896 | Factors predicting disease outcome in early stage adenocarcinoma of the uterine cervix. | European journal of obstetrics, gynecology, and reproductive biology | Eur J Obstet Gynecol Reprod Biol | 101 | 2 | 10.1016/s0301-2115(01)00524-3 | eng | 2,002 | 3 | 10 | null | null | null | [CONTEXT] Adenocarcinoma (AC) and adenosquamous carcinoma (ASC) comprise the second principal histological types of cervical carcinoma. As compared with the squamous cell cancer (SCC), these lesions are far less frequent, and their epidemiology, natural history and prognostic determinants are less well understood. [OBJ... | null | null | null | null | null | null |
11,856,110 | Urological complications of coitus. | BJU international | BJU Int | 89 | 3 | 10.1046/j.1464-4096.2001.01458.x | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVE] To ascertain the urological complications of coitus, as the proximity of the lower urinary tract to the organs of coitus exposes the tract to coital trauma. [MATERIALS AND METHODS] Medline was searched from 1966 to 2000 to identify reports on coital injuries. Publications and relevant references were retrie... | null | 0.864 | 174 | Urology | Medicine | 2,002 |
11,856,089 | Efficacy of low-dose clarithromycin triple therapy and tinidazole-containing triple therapy for Helicobacter pylori eradication. | Alimentary pharmacology & therapeutics | Aliment Pharmacol Ther | 16 | 1 | 10.1046/j.1365-2036.2002.01130.x | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] Proton pump inhibitor-based triple therapies are recommended as the first-line treatment for Helicobacter pylori eradication. [AIM] To evaluate the efficacies of low-dose clarithromycin triple therapy and tinidazole-containing triple therapy in a metronidazole resistance prevalent area and to compare the e... | null | null | null | null | null | null |
11,854,770 | Medicinal use of cannabis: history and current status. | Pain research & management | Pain Res Manag | 6 | 2 | 10.1155/2001/469629 | eng | 2,001 | null | null | null | null | null | [OBJECTIVE] To provide an overview of the history and pharmacology of cannabis in relation to current scientific knowledge concerning actual and potential therapeutic uses of cannabis preparations and pure cannabinoids. [METHODS] The literature on therapeutic uses of cannabis and cannabinoids was assessed with respect ... | null | null | null | null | null | null |
11,854,692 | Prospective evaluation of delayed technetium-99m sestamibi SPECT scintigraphy for preoperative localization of primary hyperparathyroidism. | Surgery | Surgery | 131 | 2 | 10.1067/msy.2002.119817 | eng | 2,002 | 2 | null | null | null | null | [BACKGROUND] Delayed technetium-99m sestamibi single photon emission computed tomography (SPECT) scans were prospectively analyzed in a large series of patients with primary hyperparathyroidism. [METHODS] Three hundred thirty-eight patients underwent sestamibi-SPECT and were explored. Prospective data included preopera... | null | null | null | null | null | null |
11,854,671 | High-speed cavity preparation techniques with different water flows. | The Journal of prosthetic dentistry | J Prosthet Dent | 87 | 2 | 10.1067/mpr.2002.120655 | eng | 2,002 | 2 | null | null | null | null | [STATEMENT OF PROBLEM] Cavity and tooth preparations generate heat because the use of rotary cutting instruments on dental tissues creates friction. Dental pulps cannot survive temperature increases greater than 5.5 degrees C. [PURPOSE] This study evaluated the efficiency of 3 different water flows for 2 different toot... | null | 0.475 | 160 | Medicine; Oral Surgery | Dentistry; Medicine | 2,002 |
11,854,645 | Acute renal failure complicating severe preeclampsia requiring admission to an obstetric intensive care unit. | American journal of obstetrics and gynecology | Am J Obstet Gynecol | 186 | 2 | 10.1067/mob.2002.120279 | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVE] To determine risk factors and outcomes for women with severe preeclampsia and renal failure. [STUDY DESIGN] Retrospective study from 1995 to 1998 of all women with renal failure who were admitted to the obstetric intensive care unit at Groote Schuur Hospital, South Africa. A total of 89 women were identifie... | null | 1.509 | 274 | Obstetrics and Gynecology | Medicine | 2,002 |
11,854,608 | Metastatic Crohn's disease of the forehead. | Inflammatory bowel diseases | Inflamm Bowel Dis | 8 | 2 | 10.1097/00054725-200203000-00006 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Metastatic Crohn's disease (CD) involves the presence of cutaneous granuloma distant from the intestinal lesions related to the disease, usually observed in colonic CD. [CASE HISTORY] A 35-year-old female with a permanent ileostomy following proctocolectomy for CD presented in 1999 with a 2-month history o... | null | 1.091 | 183 | Gastroenterology; Immunology and Allergy | Medicine | 2,002 |
11,852,372 | Prevalence of diabetes mellitus and impaired glucose tolerance in Benghazi Libya. | Diabetes & metabolism | Diabetes Metab | 27 | 6 | null | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVES] To assess, by a house to house study, the prevalence of diabetes, impaired glucose tolerance (IGT) and their associated risk factors in Benghazi, Libya using 75 gram oral glucose tolerance test (OGTT) and ADA 1997 and WHO 1998 diagnostic criteria. [MATERIAL AND METHODS] A multistage cluster sampling was us... | null | null | null | null | null | null |
11,852,288 | Early prediction in acute pancreatitis: the contribution of amylase and lipase levels in peritoneal fluid. | JOP : Journal of the pancreas | JOP | 1 | 2 | null | eng | 2,000 | 7 | null | null | null | null | [CONTEXT] Predicting the severity of acute pancreatitis early in the course of the disease is still difficult. [OBJECTIVE] The value of amylase and lipase levels in serum and peritoneal fluid might be of value in predicting the course of acute pancreatitis. [DESIGN] Prospective study. [PATIENTS] One-hundred and sixty-s... | null | null | null | null | null | null |
11,852,217 | Influence of heart rate on vessel visibility in noninvasive coronary angiography using new multislice computed tomography: experience in 94 patients. | Clinical imaging | Clin Imaging | 26 | 2 | 10.1016/s0899-7071(01)00371-0 | eng | 2,002 | null | null | null | null | null | [OBJECTIVES] Initial reports indicate that coronary artery lesions might be visualized with high sensitivity and specificity by the use of recently introduced multislice computed tomography (MSCT). Current CT technology offers a temporal resolution of 250 ms. In case of heart rates (HRs) >65 beats/min (bpm), however, t... | null | 0.284 | 59 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,002 |
11,852,216 | CT pulmonary angiography in the detection of pulmonary emboli: a meta-analysis of sensitivities and specificities. | Clinical imaging | Clin Imaging | 26 | 2 | 10.1016/s0899-7071(01)00366-7 | eng | 2,002 | null | null | null | null | null | [OBJECTIVE] To determine the overall sensitivity and specificity for CT pulmonary angiography (CTPA) in the diagnosis of pulmonary emboli (PE) using a meta-analysis of the published literature. [MATERIALS AND METHODS] A Medline search was constructed to include all English language publications indexed in the Index Med... | null | 0.284 | 59 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,002 |
11,851,770 | Laparoscopic diagnosis and treatment of nonpalpable testis. | International journal of urology : official journal of the Japanese Urological Association | Int J Urol | 8 | 12 | 10.1046/j.1442-2042.2001.00397.x | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] Laparoscopy has become one of the important diagnostic modalities of nonpalpable testis and has been developed and applied in the treatment of this disease. In the present study, we investigated the usefulness of laparoscopy in the diagnosis and treatment of nonpalpable testis. [METHODS] Laparoscopy was car... | null | 0.378 | 83 | Urology | Medicine | 2,001 |
11,851,664 | Liver fibrosis increases the risk of intrahepatic recurrence after hepatectomy for hepatocellular carcinoma. | The British journal of surgery | Br J Surg | 89 | 1 | 10.1046/j.0007-1323.2001.01969.x | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] Hepatocellular carcinoma (HCC) commonly develops in patients with chronic hepatitis. Intrahepatic recurrence after hepatectomy often includes nodules of new tumour in the liver remnant. The aim of this study was to examine hepatitis-related factors that might predict this type of recurrence. [METHODS] The ... | null | 1.657 | 234 | Surgery | Medicine | 2,002 |
11,851,071 | Evaluating composite health measures using Rasch modelling: an illustrative example. | Sozial- und Praventivmedizin | Soz Praventivmed | 46 | 6 | 10.1007/BF01321663 | eng | 2,001 | null | null | null | null | null | [OBJECTIVES] The purpose of the present article is to elucidate the opportunities provided by Rasch modelling in epidemiology and public health research in order to evaluate composite measures of health. [METHODS] The article gives a review of Rasch modelling in conjunction with illustrative examples based on adolescen... | null | null | null | null | null | null |
11,849,860 | Predictors of aneurysmal formation after surgical correction of aortic coarctation. | Journal of the American College of Cardiology | J Am Coll Cardiol | 39 | 4 | 10.1016/s0735-1097(01)01784-3 | eng | 2,002 | 2 | 20 | null | null | null | [OBJECTIVES] We sought to identify the predictors of aneurysmal formation after surgical correction of aortic coarctation. [BACKGROUND] In 9% of patients, aneurysms develop late after corrective surgery of coarctation of the aorta, with a 36% mortality rate if left untreated. However, the predictors of postsurgical ane... | null | 3.758 | 512 | Cardiology and Cardiovascular Medicine | Medicine | 2,002 |
11,849,522 | How consultants, hospitals, trusts and deaneries affect pre-registration house officer posts: a multilevel model. | Medical education | Med Educ | 36 | 1 | 10.1046/j.1365-2923.2002.01123.x | eng | 2,002 | 1 | null | null | null | null | [OBJECTIVE] To examine variation in reported quality and working conditions of pre-registration house officer (PRHO) posts. To use multilevel modelling to determine how much of the variation was due to the effects of consultant firms, hospitals, trusts and deaneries, as well as variation at the level of the individual ... | null | 0.886 | 171 | Education; Medicine | Medicine; Social Sciences | 2,002 |
11,849,450 | Meprin, a brush-border enzyme, plays an important role in hypoxic/ischemic acute renal tubular injury in rats. | Kidney international | Kidney Int | 61 | 3 | 10.1046/j.1523-1755.2002.00209.x | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] It has been shown that non-congenic mice strains with lower levels of renal meprin develop less renal injury following renal ischemia and reperfusion. We have demonstrated that following ischemia-reperfusion renal injury, there is a rapid shift of meprin localization and intensity from the brush border to ... | null | null | null | null | null | null |
11,849,433 | Nitric oxide synthase isoform expression in acute versus chronic anti-Thy 1 nephritis. | Kidney international | Kidney Int | 61 | 3 | 10.1046/j.1523-1755.2002.00228.x | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] Two inbred Lewis rat substrains (LEW/Moe, LEW/Maa) were identified responding differently to induction of anti-Thy 1 glomerulonephritis (aThy 1-GN). LEW/Moe rats show an acute mesangioproliferative glomerulonephritis with rapid healing of glomerular lesions within four weeks, while LEW/Maa rats develop sev... | null | null | null | null | null | null |
11,849,326 | Enhancement of bile tolerance in lactococci by Tween 80. | Journal of applied microbiology | J Appl Microbiol | 92 | 1 | 10.1046/j.1365-2672.2002.01505.x | eng | 2,002 | null | null | null | null | null | [AIMS] The aim of this study is to clarify the effect of Tween 80 on bile tolerance of lactococci. [METHODS AND RESULTS] Four out of the six strains of lactococci could grow in broth containing 0.3% bile in the presence of 1% Tween 80, but grew slightly or not at all in the absence of Tween 80. Growing with Tween 80 al... | null | 0.905 | 195 | Applied Microbiology and Biotechnology; Biotechnology; Medicine | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,002 |
11,848,647 | Medical abortion as an alternative to vacuum aspiration: first experiences with the 'abortion pill' in The Netherlands. | The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception | Eur J Contracept Reprod Health Care | 6 | 4 | null | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] To establish to what extent medical abortion is desired as a supplement to existing care provision in The Netherlands and to establish the (dis)advantages of medical abortion versus surgical vacuum aspiration. [METHODS] The research project began in November 1999 and ended in September 2000. In two abortion... | Empirical Approach; Genetics and Reproduction | null | null | null | null | null |
11,847,459 | The metabolism of the pancreas carcinogen N-nitrosobis(2-oxopropyl)amine by hamster pancreas duct epithelial cell clones; evidence for different metabolic efficiencies and response to cytochrome P450 inducers. | JOP : Journal of the pancreas | JOP | 1 | 1 | null | eng | 2,000 | 5 | null | null | null | null | [CONTEXT] We have isolated five stable clones from a primary culture of Syrian golden hamster pancreatic duct epithelial cells and have designated them as CK1 through CK5. [DESIGN] Here we describe the ability of two of these, CK1 and CK5, to metabolize the pancreas carcinogen N-nitrosobis(2-oxopropyl)amine. The metabo... | null | null | null | null | null | null |
11,847,302 | Cost-effectiveness of preimmunization hepatitis B screening in high-risk adolescents. | Public health reports (Washington, D.C. : 1974) | Public Health Rep | 116 | 2 | 10.1093/phr/116.2.165 | eng | 2,001 | null | null | null | null | null | [OBJECTIVE] The goals of this study were to estimate seroprevalence of prior hepatitis B infection among high-risk adolescents and to determine the cost-effectiveness of prevaccination immunity screening. [METHODS] The authors computed a "break-even" seroprevalence level calculated from current vaccine and administrati... | null | 0.475 | 111 | Public Health, Environmental and Occupational Health | Medicine | 2,001 |
11,846,901 | Implications of excessive fibrinolysis and alpha(2)-plasmin inhibitor deficiency in patients with severe head injury. | Neurosurgery | Neurosurgery | 49 | 5 | 10.1097/00006123-200111000-00011 | eng | 2,001 | 11 | null | null | null | null | [OBJECTIVE] To evaluate the involvement of the fibrinolytic system, especially focused on alpha(2)-plasmin inhibitor, in patients with head injury. [METHODS] This study consisted of 47 patients with isolated blunt head trauma in whom blood sampling could be initiated within 3 hours after injury. Patients were divided i... | null | 1.655 | 229 | Neurology; Surgery | Medicine | 2,001 |
11,846,364 | A population-based hepatitis B vaccination coverage survey among Asian and Pacific Islander American students in Alachua County, Florida. | Asian American and Pacific Islander journal of health | Asian Am Pac Isl J Health | 9 | 2 | null | eng | 2,001 | null | null | null | null | null | [PURPOSE] The goal of this project was to evaluate the impact of the Florida mandatory hepatitis B vaccination law on the immunization status of Asian American and Pacific Islander (AAPI) students in Gainesville. [METHODS] We (1) compared the differences of hepatitis B immunization rate between students in grades seven... | null | null | null | null | null | null |
11,845,640 | Literacy in the health care system: a study on open heart surgery patients. | Journal of the American Academy of Nurse Practitioners | J Am Acad Nurse Pract | 14 | 1 | 10.1111/j.1745-7599.2002.tb00069.x | eng | 2,002 | 1 | null | null | null | null | [PURPOSE] To determine if patients recovering from open heart surgery were able to read and understand written discharge instructions and further to analyze the level of difficulty of standard discharge instructions and consent forms for open heart surgery. [DATA SOURCES] After screening for visual acuity and efficienc... | null | 0.127 | 54 | Nursing | Nursing | 2,002 |
11,845,603 | Clinical versus molecular diagnosis of heterozygous familial hypercholesterolaemia in the diverse South African population. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde | S Afr Med J | 91 | 12 | null | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] Familial hypercholesterolaemia (FH) is a common genetic disease characterised by strikingly elevated plasma cholesterol concentration, which can lead to premature coronary death if left untreated. In this study DNA diagnosis of FH, which allows detection before onset of clinical symptoms, was evaluated agai... | null | null | null | null | null | null |
11,844,959 | Prognostic value of serum tumor markers in patients with lung cancer. | Respiration; international review of thoracic diseases | Respiration | 69 | 1 | 10.1159/000049366 | eng | 2,002 | null | null | null | null | null | [BACKGROUND] The role of tumor markers in the diagnosis and prognosis of lung cancer is under investigation. [OBJECTIVES] The aim of this study was to investigate the diagnostic and prognostic significance of pre-therapeutic levels of various serum tumor markers, CYFRA 21-1, neuron-specific enolase (NSE), tissue polype... | null | null | null | null | null | null |
11,844,119 | Characteristics of patients with lung cancer under the age of 45 years: a case control study. | Respirology (Carlton, Vic.) | Respirology | 6 | 4 | 10.1046/j.1440-1843.2001.00348.x | eng | 2,001 | 12 | null | null | null | null | [OBJECTIVE] The aim of this study was to define the clinical and pathological features associated with lung cancer diagnosed in persons under the age of 45 compared with lung cancer in an older population of greater than 45 years. [METHODOLOGY] A case control study was undertaken. Cases were defined as patients diagnos... | null | 0.18 | 113 | Pulmonary and Respiratory Medicine | Medicine | 2,001 |
11,843,497 | The CarboMedics prosthetic heart valve: experience with 1,084 implants. | The Journal of heart valve disease | J Heart Valve Dis | 11 | 1 | null | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND AND AIM OF THE STUDY] The study aim was to evaluate our clinical experience with the CarboMedics heart valve prosthesis. [METHODS] Between October 1991 and December 2000, 942 consecutive patients (514 males, 428 females; mean age 58+/-11 years; range: 6-78 years) underwent mechanical valve implantation with... | null | null | null | null | null | null |
11,843,456 | A pivoting appliance for intracavitary brachytherapy in patients with reduced mouth opening. | The International journal of prosthodontics | Int J Prosthodont | 14 | 2 | null | eng | 2,001 | null | null | null | null | null | [PURPOSE] The risks of radiotherapy to normal tissues are well known. In many cases, a tumor patient suffering a relapse cannot undergo radiotherapy a second time. One exception may be the local application of brachytherapy. Afterloading devices allow the position of radiating materials near the site for treatment exac... | null | 0.667 | 110 | Medicine; Oral Surgery | Dentistry; Medicine | 2,001 |
11,841,053 | The three-dimensional effects of orthodontic treatment on the facial soft tissues--a preliminary study. | British dental journal | Br Dent J | 192 | 2 | 10.1038/sj.bdj.4801305 | eng | 2,002 | 1 | 26 | null | null | null | [OBJECTIVE] To examine the three-dimensional effects of extraction and non-extraction orthodontic treatment on the facial soft tissues. [SETTING] Department of Orthodontics, Royal London Hospital. [DESIGN] Longitudinal study of two prospective cohorts of patients who were attending for orthodontic treatment. METHOD 12 ... | null | null | null | null | null | null |
11,839,883 | The "window" of slow pathway conduction after ablation and recurrence of atrioventricular nodal reentrant tachycardia. | Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing | J Interv Card Electrophysiol | 6 | 1 | 10.1023/a:1014183401028 | eng | 2,002 | 2 | null | null | null | null | [INTRODUCTION] Slow pathway (SP) conduction often persists following radiofrequency (RF) catheter ablation of atrioventricular nodal reentrant tachycardia (AVNRT). An association between persistent SP conduction, as evidenced by discontinuous AV nodal conduction curves, and recurrent tachycardia has not been establishe... | null | 0.643 | 66 | Medicine; Cardiology and Cardiovascular Medicine; Physiology | Medicine | 2,002 |
11,839,834 | Modulation of cerebral GABA by topiramate, lamotrigine, and gabapentin in healthy adults. | Neurology | Neurology | 58 | 3 | 10.1212/wnl.58.3.368 | eng | 2,002 | 2 | 12 | null | null | null | [BACKGROUND] Anticonvulsant drugs have multiple mechanisms of action. Recent in vivo MRS studies suggest that cerebral gamma-aminobutyric acid (GABA) increases occur with the administration of certain anticonvulsants in humans. [OBJECTIVE] To investigate the effect of topiramate, gabapentin, and lamotrigine on cerebral... | null | 2.373 | 422 | Neurology | Medicine | 2,002 |
11,839,713 | Acute restraint stress activates functional NK1 receptor in the colon of female rats: involvement of steroids. | Gut | Gut | 50 | 3 | 10.1136/gut.50.3.349 | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND AND AIMS] Psychological factors have been implicated in the aetiology of irritable bowel syndrome characterised by intestinal altered motility and visceral hypersensitivity. Similar disorders have been found in rats under stressful conditions. The role of tachykinins in bowel dysfunctions caused by stress i... | null | 2.104 | 364 | Gastroenterology | Medicine | 2,002 |
11,839,369 | Interactive effect of cytochrome P450 17alpha-hydroxylase and dopamine D3 receptor gene polymorphisms on abnormal involuntary movements in chronic schizophrenia. | Biological psychiatry | Biol Psychiatry | 51 | 3 | 10.1016/s0006-3223(01)01302-6 | eng | 2,002 | 2 | 1 | null | null | null | [BACKGROUND] Tardive dyskinesia is a chronic adverse effect of anti psychotic drugs, where association with a polymorphic site in the dopamine D3 receptor gene has been previously reported. Cytochrome P 450 17alpha-hydroxylase activity has been implicated with modulation of central dopamine release as well as neuroprot... | null | 3.32 | 367 | Biological Psychiatry | Neuroscience | 2,002 |
11,838,845 | Pulmonary hypertension in systemic lupus erythematosus: evaluation of clinical characteristics and response to immunosuppressive treatment. | The Journal of rheumatology | J Rheumatol | 29 | 2 | null | eng | 2,002 | 2 | null | null | null | null | [OBJECTIVE] To clarify the clinical features of systemic lupus erythematosus (SLE) complicated with pulmonary hypertension (PH) and to evaluate the efficacy of immunosuppressive treatment. [METHODS] Case records were reviewed for 194 patients with SLE who were admitted to Aoyama Hospital of Tokyo Women's Medical Univer... | null | 1.022 | 201 | Rheumatology; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,002 |
11,838,833 | Stroke and mental health care: a record linkage study. | Social psychiatry and psychiatric epidemiology | Soc Psychiatry Psychiatr Epidemiol | 36 | 12 | 10.1007/s127-001-8201-x | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] Stroke is associated with psychiatric morbidity but little is known about mental health care use in stroke patients. [METHOD] A probability record linkage study was conducted linking stroke cases admitted to a teaching hospital serving a catchment area between 1987 and 1995 with records from a psychiatric ... | null | 1.142 | 152 | Health; Psychiatry and Mental Health; Social Psychology; Epidemiology | Medicine; Psychology; Social Sciences | 2,001 |
11,838,611 | Environmental risk factors and Crohn's disease: a population-based, case-control study in Spain. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver | Dig Liver Dis | 33 | 9 | 10.1016/s1590-8658(01)80693-9 | eng | 2,001 | 12 | null | null | null | null | [BACKGROUND] The pathogenesis of inflammatory bowel disease probably involves an interaction between genetic and environmental factors: cigarette smoking, appendectomy and oral contraceptives have been the factors most frequently linked to its aetiology [AIM] To analyse the association between known environmental risk ... | null | 0.433 | 113 | Gastroenterology; Hepatology | Medicine | 2,001 |
11,837,698 | Transport activity of human MRP3 expressed in Sf9 cells: comparative studies with rat MRP3. | Pharmaceutical research | Pharm Res | 19 | 1 | 10.1023/a:1013699130991 | eng | 2,002 | 1 | null | null | null | null | [PURPOSE] Multidrug resistance-associated protein 3 (MRP3) was initially cloned as a hepatic transporter induced under cholestatic/ hyperbilirubinemic conditions. In the present study, transport property of human MRP3 (hMRP3) was compared with that of rat MRP3 (rMRP3). [METHODS] Adenosine 5' triphosphate (ATP)-dependen... | null | 1.012 | 235 | Biotechnology; Organic Chemistry; Pharmaceutical Science; Pharmacology; Pharmacology; Molecular Medicine | Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,002 |
11,836,539 | Conization, frozen section examination, and planned hysterectomy in the treatment of high-grade cervical intraepithelial neoplasia. | Revista do Hospital das Clinicas | Rev Hosp Clin Fac Med Sao Paulo | 56 | 6 | 10.1590/s0041-87812001000600002 | eng | 2,001 | null | null | null | null | null | [PURPOSE] We tested the role of frozen section examination of the cone specimen in the evaluation of the resection margin status and to rule out invasion in patients with high-grade cervical intraepithelial neoplasia. [METHODS] Twenty-five patients with cervical intraepithelial neoplasia underwent conization followed b... | null | null | null | null | null | null |
11,835,947 | Trends in the incidence of coronary heart disease and stroke and the prevalence of cardiovascular risk factors among Japanese men from 1963 to 1994. | The American journal of medicine | Am J Med | 112 | 2 | 10.1016/s0002-9343(01)01053-1 | eng | 2,002 | 2 | 1 | null | null | null | [PURPOSE] To determine trends in the incidence of cardiovascular disease in Japan, we examined observational data on coronary heart disease, stroke, and cardiovascular risk factors among urban Japanese working men. [SUBJECTS AND METHODS] The surveyed population included all male employees aged 40 to 59 years who worked... | null | 1.979 | 262 | Medicine | Medicine | 2,002 |
11,835,716 | Relationship between changes of N-methyl-D-aspartate receptor activity and brain edema after brain injury in rats. | Chinese journal of traumatology = Zhonghua chuang shang za zhi | Chin J Traumatol | 4 | 3 | null | eng | 2,001 | 8 | null | null | null | null | [OBJECTIVE] To investigate the relationship between the changes of N-methyl-D aspartate (NMDA) receptor activity and brain edema after injury in rats. [METHODS] The brain injury models were made by using a free-falling body. The treatment model was induced by means of injecting AP5 into lateral ventricle before brain i... | null | null | null | null | null | null |
11,835,420 | The risk of lower urinary tract symptoms five years after the first delivery. | Neurourology and urodynamics | Neurourol Urodyn | 21 | 1 | 10.1002/nau.2198 | eng | 2,002 | null | null | null | null | null | [AIM OF THE STUDY] To estimate the prevalence and 5-year incidence of lower urinary tract symptoms (LUTS) after the first delivery and to evaluate the impact of pregnancy per se and delivery per se on long-lasting symptoms. [MATERIALS AND METHODS] A longitudinal cohort study of 305 primiparae questioned a few days, 3 m... | null | 1.296 | 112 | Neurology; Urology | Medicine | 2,002 |
11,834,902 | Biopsies of the transitional zone of the prostate. Should it be done on a routine basis, when and why? | Urologia internationalis | Urol Int | 68 | 2 | 10.1159/000048430 | eng | 2,002 | null | null | null | null | null | [PURPOSE] In this prospective study we try to evaluate the necessity of performing additional transitional zone biopsies as part of the standard sextant biopsies procedure in order to detect prostate cancer. [MATERIALS AND METHODS] During a 12-month period we performed biopsies in 420 patients. All patients had two add... | null | 0.347 | 67 | Urology | Medicine | 2,002 |
11,834,901 | Improved continence after radical retropubic prostatectomy using two pubo-urethral suspension stitches. | Urologia internationalis | Urol Int | 68 | 2 | 10.1159/000048429 | eng | 2,002 | null | null | null | null | null | [OBJECTIVES] To determine if placement of urethral suspension stitches during radical retropubic prostatectomy improves postoperative urinary continence. [METHODS] Between January 1997 and January 1998 we performed radical retropubic prostatectomy on 50 men. The first 25 consecutive men had their surgery without urethr... | null | 0.347 | 67 | Urology | Medicine | 2,002 |
11,834,067 | Apico-aortic conduits in children with severe left ventricular outflow tract obstruction. | The Annals of thoracic surgery | Ann Thorac Surg | 73 | 1 | 10.1016/s0003-4975(01)03291-x | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] Infrequently, congenital heart defects are complicated by left ventricular outflow tract obstruction (LVOTO) not amenable to conventional reconstruction. Apico-aortic conduits provide a means of palliating such patients until definitive repair is possible. The purpose of this study was to review a single i... | null | 1.504 | 230 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,002 |
11,834,013 | Melatonin attenuates posttransplant lung ischemia-reperfusion injury. | The Annals of thoracic surgery | Ann Thorac Surg | 73 | 1 | 10.1016/s0003-4975(01)03101-0 | eng | 2,002 | 1 | null | null | null | null | [BACKGROUND] Melatonin, a pineal hormone, is a free radical scavenger and an antioxidant. The purpose of this study was to assess the protective effect of melatonin on posttransplant lung ischemia-reperfusion injury. [METHODS] Rat single-lung transplantation was performed in two (n = 10) experimental groups after 18 ho... | null | 1.504 | 230 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,002 |
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