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11,832,454
Experimental ulcers alter voltage-sensitive sodium currents in rat gastric sensory neurons.
Gastroenterology
Gastroenterology
122
2
10.1053/gast.2002.31026
eng
2,002
2
null
null
null
null
[BACKGROUND AND AIMS] Voltage-dependent Na+ currents are important determinants of excitability. We hypothesized that gastric inflammation alters Na+ current properties in primary sensory neurons. [METHODS] The stomach was surgically exposed in rats to inject the retrograde tracer 1.1'-dioctadecyl-3,3,3,'3-tetramethyli...
null
3.536
482
Gastroenterology
Medicine
2,002
11,832,257
High-resolution MRI and micro-FE for the evaluation of changes in bone mechanical properties during longitudinal clinical trials: application to calcaneal bone in postmenopausal women after one year of idoxifene treatment.
Clinical biomechanics (Bristol, Avon)
Clin Biomech (Bristol)
17
2
10.1016/s0268-0033(01)00110-3
eng
2,002
2
null
null
null
null
[OBJECTIVE] To investigate whether recently developed in vivo high-resolution magnetic resonance-imaging and micro-finite element techniques can monitor changes in bone mechanical properties during long-term clinical trials aiming at evaluating the efficacy of new drugs for the treatment of osteoporosis. [DESIGN] Compa...
null
null
null
null
null
null
11,830,812
Rotational muscle strength of the limb after anterior cruciate ligament reconstruction using semitendinosus and gracilis tendon.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Arthroscopy
18
2
10.1053/jars.2002.29894
eng
2,002
2
null
null
null
null
[PURPOSE] To investigate the influence of harvesting semitendinosus and gracilis tendons on the rotational muscle strength of the limb after anterior cruciate ligament (ACL) reconstruction. [TYPE OF STUDY] Prospective study. [METHODS] We performed a prospective study of 62 consecutive (34 male, 28 female) patients with...
null
null
null
null
null
null
11,830,307
A multicentre randomized/controlled trial of a conventional versus modestly accelerated radiotherapy in the laryngeal cancer: influence of a 1 week shortening overall time.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Radiother Oncol
62
1
10.1016/s0167-8140(01)00494-7
eng
2,002
1
null
null
null
null
[BACKGROUND AND PURPOSE] To compare in a phase III study the loco-regional control, disease-free survival and overall survival induced by an accelerated regimen (AF) as compared with conventional regimen (CF) and to analyze the early and late post-radiation morbidity in both arms. [MATERIALS AND METHODS] Patients with ...
null
1.236
189
Hematology; Oncology; Radiology, Nuclear Medicine and Imaging
Medicine
2,002
11,829,698
Effects of diet and simvastatin on serum lipids, insulin, and antioxidants in hypercholesterolemic men: a randomized controlled trial.
JAMA
JAMA
287
5
10.1001/jama.287.5.598
eng
2,002
2
6
null
null
null
[CONTEXT] Limited information exists on the interaction between diet and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) and the interaction's effect on serum lipid and lipoprotein levels, insulin sensitivity, and circulating antioxidant vitamin and provitamin levels. [OBJECTIVE] To evaluate the se...
null
null
null
null
null
null
11,829,431
Adverse effects of perioperative transfusion on patients with stage III and IV gastric cancer.
Annals of surgical oncology
Ann Surg Oncol
9
1
10.1245/aso.2002.9.1.5
eng
2,002
null
null
null
null
null
[BACKGROUND] The degree of immunomodulation by perioperative blood transfusion and its resultant effects on cancer surgery are a subject of controversy. We evaluated the prognostic effects of perioperative blood transfusion on gastric cancer surgery. [METHODS] A total of 1710 patients who underwent curative gastrectomy...
null
1.483
210
Oncology; Surgery
Medicine
2,002
11,828,835
Antidepressant medication and suicide in Sweden.
Pharmacoepidemiology and drug safety
Pharmacoepidemiol Drug Saf
10
6
10.1002/pds.618
eng
2,001
null
null
null
null
null
[OBJECTIVE] To explore a possible temporal association between changes in antidepressant sales and suicide rates in different age groups. [METHODS] A time series analysis using a two-slope model to compare suicide rates in Sweden before and after introduction of the selective serotonin reuptake inhibitors, SSRIs. [RESU...
null
0.383
113
Pharmacology; Epidemiology
Medicine
2,001
11,828,556
Carpal tunnel release by limited palmar incision vs traditional open technique: randomized controlled trial.
Croatian medical journal
Croat Med J
43
1
null
eng
2,002
2
null
null
null
null
[AIM] To compare a limited palmar incision for carpal tunnel release (CTR) with a traditional open technique, which is still considered the gold standard. [METHODS] Seventy-two patients with a carpal tunnel syndrome were individually randomized into the trial (limited incision CTR) (n=36) and control group (traditional...
null
null
null
null
null
null
11,828,288
Contrasting natures of lung growth after transplantation and lobectomy.
The Journal of thoracic and cardiovascular surgery
J Thorac Cardiovasc Surg
123
2
10.1067/mtc.2002.119339
eng
2,002
2
null
null
null
null
[OBJECTIVE] We hypothesized that posttransplantation lung growth in an immature recipient and postlobectomy compensatory lung growth are two distinct processes. [METHODS] Mature swine underwent left upper lobectomy, and growth of the left lower lobe was studied after 2 weeks and after 3 months. Left lower lobes from an...
null
1.904
225
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,002
11,827,249
Measuring outcomes of type 2 diabetes disease management program in an HMO setting.
Southern medical journal
South Med J
95
1
null
eng
2,002
1
null
null
null
null
[BACKGROUND] There is a need to evaluate empirical disease management programs used in managing chronic diseases such as diabetes mellitus in managed care settings. [METHODS] We analyzed data from 252 patients with type 2 diabetes before and 1 year after enrollment in a disease management program. We examined clinical ...
null
null
null
null
null
null
11,826,995
The population requirement for cataract extraction: a cross-sectional study.
Eye (London, England)
Eye (Lond)
15
Pt 6
10.1038/eye.2001.242
eng
2,001
12
null
null
null
null
[PURPOSE] To examine the distribution in the population of indications for cataract extraction in order to relate demand for this procedure to the capacity for satisfying it. [METHODS] An age-stratified random population sample of 2783 individuals aged 55 years and over was taken from inner-city, urban and rural areas ...
null
null
null
null
null
null
11,826,595
Harmonic imaging of the brain parenchyma in a dog model following NC100100 (Sonazoid) bolus injection.
Journal of neuroimaging : official journal of the American Society of Neuroimaging
J Neuroimaging
12
1
10.1111/j.1552-6569.2002.tb00087.x
eng
2,002
1
null
null
null
null
[BACKGROUND AND PURPOSE] NC100100 (Sonazoid) is a new perfluorocarbon-based ultrasound contrast agent (UCA) that has not been introduced to transcranial harmonic imaging. [METHODS] In an animal study on 6 beagle dogs, the authors performed harmonic power Doppler and gray-scale imaging (SONOS 5500, S4 probe) after bolus...
null
0.56
75
Medicine; Neurology; Radiology, Nuclear Medicine and Imaging
Medicine
2,002
11,826,234
Expression of activation markers and cytokine mRNA by peripheral blood CD4 and CD8 T cells in atopic and nonatopic childhood asthma: effect of inhaled glucocorticoid therapy.
Pediatrics
Pediatrics
109
2
10.1542/peds.109.2.e24
eng
2,002
2
null
null
null
null
[HYPOTHESIS] Activated CD8 as well as CD4 T cells contribute to the production of asthma-relevant cytokines in both atopic and nonatopic childhood asthma. [OBJECTIVES] To measure the percentages of peripheral blood CD4 and CD8 T cells expressing naïve/memory (CD45RA/CD45RO) and activation (HLA-DR, CD25) markers, as wel...
null
2.01
409
Pediatrics, Perinatology and Child Health
Medicine
2,002
11,825,735
The elephant trunk technique: operative results in 100 consecutive patients.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Eur J Cardiothorac Surg
21
2
10.1016/s1010-7940(01)01088-0
eng
2,002
2
null
null
null
null
[OBJECTIVES] To describe morbidity and mortality in patients undergoing the elephant trunk (ET) implantation as the first stage in the repair of their mega aorta and to assess determinants for the occurrence of complications. [METHODS] One hundred consecutive patients undergoing an ET implantation between 1984 and June...
null
1.163
158
Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,002
11,824,794
Effects of interleukin-8 and Helicobacter pylori on histamine release from isolated canine gastric mucosal mast cells.
Journal of gastroenterology
J Gastroenterol
37
1
10.1007/s535-002-8126-y
eng
2,002
1
null
null
null
null
[BACKGROUND] In recent studies, the involvement of mast cells in the pathogenesis of Helicobacter pylori infection was suggested. In the present study, using isolated canine gastric mucosal mast cells, we undertook to elucidate the effects of interleukin-8 (IL-8) and H. pylori on histamine release from these cells. [ME...
null
0.512
140
Gastroenterology
Medicine
2,002
11,824,671
Results of aortic arch repair with hypothermic circulatory arrest and retrograde cerebral perfusion.
Journal of cardiac surgery
J Card Surg
16
3
10.1111/j.1540-8191.2001.tb00515.x
eng
2,001
null
null
null
null
null
[BACKGROUND] Repair of aortic arch pathology is reliably performed with hypothermic circulatory arrest, but the best method of brain protection is controversial. [METHODS] We reviewed a consecutive series of 67 patients who had aortic arch repair with hypothermic circulatory arrest. Retrograde perfusion of arterial blo...
null
0.544
69
Cardiology and Cardiovascular Medicine; Surgery
Medicine
2,001
11,823,765
Persistence of delays in presentation and treatment for patients with acute myocardial infarction: The GUSTO-I and GUSTO-III experience.
Annals of emergency medicine
Ann Emerg Med
39
2
10.1067/mem.2002.121402
eng
2,002
2
null
null
null
null
[STUDY OBJECTIVE] Early treatment with fibrinolytic therapy substantially decreases mortality in acute myocardial infarction (AMI). We examined delays to hospital arrival and treatment in 2 large, multinational, randomized trials of fibrinolytic therapy: Global Utilization of Streptokinase and Tissue Plasminogen Activa...
null
1.137
178
Emergency Medicine
Medicine
2,002
11,823,676
17beta-estradiol increases rat cerebrovascular prostacyclin synthesis by elevating cyclooxygenase-1 and prostacyclin synthase.
Stroke
Stroke
33
2
10.1161/hs0202.102732
eng
2,002
2
null
null
null
null
[BACKGROUND AND PURPOSE] It has been reported that estrogens modulate peripheral vascular synthesis of vasodilatory hormones, including prostacyclin. If this occurs in the cerebral circulation, it could have important consequences in the modulation of cerebral hemodynamic function and improvement of stroke outcome. We ...
null
2.816
370
Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience
Medicine; Neuroscience; Nursing
2,002
11,823,360
Identifying domestic violence: cross sectional study in primary care.
BMJ (Clinical research ed.)
BMJ
324
7332
10.1136/bmj.324.7332.274
eng
2,002
2
2
null
null
null
[OBJECTIVES] To measure the prevalence of domestic violence among women attending general practice; test the association between experience of domestic violence and demographic factors; evaluate the extent of recording of domestic violence in records held by general practices; and assess acceptability to women of scree...
null
1.087
519
Medicine
Medicine
2,002
11,823,051
Modulation of MDM2/p53 and cyclin-activating kinase during the megakaryocyte differentiation of human erythroleukemia cells.
Experimental hematology
Exp Hematol
30
2
10.1016/s0301-472x(01)00780-9
eng
2,002
2
null
null
null
null
[OBJECTIVE] This study was undertaken to address the involvement of CDK activating kinase (CAK), p53, and MDM2 proteins in the mitotic arrest associated with the acquisition of a polyploid DNA content during megakaryocyte differentiation of human erythroleukemia (HEL) cells. [METHODS] To evaluate this mechanism we inve...
null
1.379
131
Cancer Research; Hematology; Cell Biology; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,822,997
A double-blind, placebo-controlled study of antidepressant augmentation with mirtazapine.
Biological psychiatry
Biol Psychiatry
51
2
10.1016/s0006-3223(01)01262-8
eng
2,002
1
15
null
null
null
[BACKGROUND] A previous pilot study of open-label mirtazapine augmentation conducted by the authors in 20 depressed patients yielded a 55% response rate at week 4. A double-blind controlled trial was undertaken to further elucidate the efficacy of this intervention. [METHODS] 26 adult outpatients with persistent major ...
null
3.32
367
Biological Psychiatry
Neuroscience
2,002
11,822,573
Carrying on: the experience of premature menopause in women with early stage breast cancer.
Nursing research
Nurs Res
51
1
10.1097/00006199-200201000-00003
eng
2,002
null
null
null
null
null
[BACKGROUND] The survival benefit of adjuvant chemotherapy for breast cancer is established but the experience of organ system toxicity for women, specifically ovarian toxicity, is not fully known. [OBJECTIVES] Th e purpose of the study was to develop asubstantive theory that would describe and explain women's response...
null
null
null
null
null
null
11,822,527
The theory of planned behavior as a model of intentions for fighting among African American and Latino adolescents.
Maternal and child health journal
Matern Child Health J
5
4
10.1023/a:1013032906379
eng
2,001
12
null
null
null
null
[OBJECTIVES] To test the theory of planned behavior as a model for predicting and understanding behavioral intentions for fighting among inner-city adolescents and to determine whether its predictive power differs as a function of ethnicity (African American versus Latino). [METHODS] Participants were 956 (511 females,...
null
0.365
109
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health; Public Health, Environmental and Occupational Health; Epidemiology
Medicine
2,001
11,822,111
Toothbrushing competency among high-risk grade one students: an evaluation of two methods of dental health education.
Journal of public health dentistry
J Public Health Dent
61
4
10.1111/j.1752-7325.2001.tb03391.x
eng
2,001
null
null
null
null
null
[OBJECTIVE] To evaluate the effectiveness of two methods of dental health education (DHE) for improving toothbrushing competency among grade one students at high risk for dental diseases. [METHODS] Fifty elementary schools in the former city of North York, Ontario, Canada, were assigned to one of two groups. In one gro...
null
0.539
74
Dentistry; Public Health, Environmental and Occupational Health
Dentistry; Medicine
2,001
11,821,803
A 16-year experience in performing hepatic resection in 303 patients with hepatocellular carcinoma: 1985-2000.
Surgery
Surgery
131
1 Suppl
10.1067/msy.2002.119497
eng
2,002
1
null
null
null
null
[BACKGROUND] Hepatic resection is an accepted therapeutic modality for hepatocellular carcinoma (HCC). Over the past 2 decades, liver surgery has evolved to a refined and deliberate operation. In the present study surgical results are analyzed with an aim toward further improving the treatment of HCC. [METHODS] We stud...
null
null
null
null
null
null
11,821,795
The role of adenoma for colorectal cancer development: differences in the distribution of adenoma with low-grade dysplasia, high-grade dysplasia, and cancer that invades the submucosa.
Surgery
Surgery
131
1 Suppl
10.1067/msy.2002.119360
eng
2,002
1
null
null
null
null
[BACKGROUND] The purpose of this study was to elucidate the role of adenoma in the early stage of colorectal cancer development, we focused on the clinicopathologic relationship between adenoma with low-grade dysplasia (ALGD), adenoma with high-grade dysplasia (AHGD), and cancer that invades the submucosa in the colore...
null
null
null
null
null
null
11,821,469
Role of radiotherapy in the treatment of supratentorial primitive neuroectodermal tumors in childhood: results of the prospective German brain tumor trials HIT 88/89 and 91.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
J Clin Oncol
20
3
10.1200/JCO.2002.20.3.842
eng
2,002
2
1
null
null
null
[PURPOSE] To evaluate the outcome of children with supratentorial primitive neuroectodermal tumors after surgery, irradiation, and chemotherapy and to identify factors predictive for survival. [PATIENTS AND METHODS] Sixty-three children in the prospective trials HIT 88/89 and HIT 91 were eligible. Complete resection wa...
null
4.274
646
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,924,332
Diagnosing and treating Alzheimer's disease: a practitioner's overview.
Journal of the American Academy of Nurse Practitioners
J Am Acad Nurse Pract
14
3
10.1111/j.1745-7599.2002.tb00100.x
eng
2,002
3
null
null
null
null
[PURPOSE] To provide an overview of current diagnostic protocols of Alzheimer's disease (AD), screening techniques, tests, and a review of standard and new treatments. [DATA SOURCES] Selected articles from the scientific literature, online sources, and standard texts were examined. [CONCLUSIONS] Standard tools, such as...
null
0.127
54
Nursing
Nursing
2,002
11,922,535
Self-directed learning: looking at outcomes with medical students.
Family medicine
Fam Med
34
3
null
eng
2,002
3
null
null
null
null
[BACKGROUND AND OBJECTIVES] Self-directed learning (SDL) skills are thought to be associated with lifelong learning. This study assessed the degree of readiness for SDL in third-year medical students who participated in a problem-based learning (PBL) curriculum during thefirst 2 years of medical school. [METHODS] A tot...
null
0.552
77
Family Practice
Medicine
2,002
11,922,383
Evaluating a visual field screening test for glaucoma: how the choice of the gold standard affects the validity of the test.
Ophthalmic epidemiology
Ophthalmic Epidemiol
8
5
10.1080/09286586.2001.11644258
eng
2,001
12
null
null
null
null
[OBJECTIVE] To examine the effects of the gold standard on sensitivity, specificity, and area under the ROC curve when determining the validity of a screening test. [METHODS] Fifty-eight people were recruited from a Veterans' Administration eye clinic. Screening included testing with the 26-point oculokinetic perimeter...
null
1.033
78
Ophthalmology; Epidemiology
Medicine
2,001
11,922,208
The usefulness of dipyridamole thallium-201 single photon emission computed tomography for predicting perioperative cardiac events in patients undergoing non-cardiac vascular surgery.
Annals of nuclear medicine
Ann Nucl Med
16
1
10.1007/BF02995291
eng
2,002
2
null
null
null
null
[UNLABELLED] The aim of this study was to evaluate the usefulness of dipyridamole Tl-201 myocardium single photon emission computed tomography (201Tl-SPECT) for predicting perioperative cardiac events in patients with arteriosclerosis obliterans (ASO) and abdominal aortic aneurysm (AAA) undergoing non-cardiac vascular ...
null
0.346
68
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,002
11,923,678
Combined odontoid and jefferson fracture in a child: a case report.
Spine
Spine (Phila Pa 1976)
27
7
10.1097/00007632-200204010-00022
eng
2,002
4
1
null
null
null
[STUDY DESIGN] A case of combined odontoid and Jefferson fracture is reported. [OBJECTIVE] To alert spine physicians to the rare combination of an odontoid and Jefferson fracture in a child. [METHODS] A 5-year old boy presented with neck pain and torticollis after falling on his head from a four-wheeler that had rolled...
null
1.336
300
Neurology; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,002
11,922,920
Plasma alpha2-HS glycoprotein concentrations in patients with acute myocardial infarction quantified by a modified ELISA.
Clinica chimica acta; international journal of clinical chemistry
Clin Chim Acta
319
1
10.1016/s0009-8981(02)00013-x
eng
2,002
5
7
null
null
null
[BACKGROUND] Human alpha2-HS glycoprotein (alpha2-HSG) is synthesized and secreted by the liver into circulation. Plasma concentrations of alpha2-HSG decrease significantly following infection, inflammation and malignancy. Since increased plasma concentrations of C-reactive protein are observed in patients with acute m...
null
null
null
null
null
null
11,921,315
Is there a kink in consumers' threshold value for cost-effectiveness in health care?
Health economics
Health Econ
11
2
10.1002/hec.655
eng
2,002
3
null
null
null
null
[BACKGROUND] A reproducible observation is that consumers' willingness-to-accept (WTA) monetary compensation to forgo a program is greater than their stated willingness-to-pay (WTP) for the same benefit. Several explanations exist, including the psychological principle that the utility of losses weighs heavier than gai...
null
null
null
null
null
null
11,920,893
Prenatal diagnosis of long QT syndrome using magnetocardiography: a case report and review of the literature.
Prenatal diagnosis
Prenat Diagn
22
3
10.1002/pd.283
eng
2,002
3
null
null
null
null
[OBJECTIVES] To investigate the usefulness of magnetocardiography (MCG) in the prenatal diagnosis of fetal long QT syndrome. [METHODS] Fetal MCG was recorded in a case of fetal long QT syndrome suspected in utero. The literature on the prenatal diagnosis of fetal long QT syndrome was also reviewed. [RESULTS] The MCG wa...
null
0.739
110
Obstetrics and Gynecology; Genetics
Medicine
2,002
11,920,521
The association between breast carcinoma and meningioma in women.
Cancer
Cancer
94
6
10.1002/cncr.10410
eng
2,002
3
15
null
null
null
[BACKGROUND] Published case reports of a possible association between meningioma and breast carcinoma are not uncommon in the literature. Four published analytic studies have addressed this suggested association specifically. Three of these studies reported significant associations, with relative risk estimates mostly ...
null
1.595
349
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,920,408
Autoantibody to hLSm4 and the heptameric LSm complex in anti-Sm sera.
Arthritis and rheumatism
Arthritis Rheum
46
3
10.1002/art.10220
eng
2,002
3
null
null
null
null
[OBJECTIVE] To characterize the 15-kd human SmD-like autoantigen and its associated proteins previously shown to be recognized by IgM antibodies in patients with Epstein-Barr virus (EBV)-induced infectious mononucleosis. [METHODS] The full-length complementary DNA for the 15-kd protein was expressed as recombinant prot...
null
null
null
null
null
null
11,920,270
Assessing the Cox model assumption as a statistical tool for classifying lymphomas.
The hematology journal : the official journal of the European Haematology Association
Hematol J
2
5
10.1038/sj.thj.6200125
eng
2,001
null
null
null
null
null
[INTRODUCTION] The Cox model is widely used in medical research for comparing survival. Lymphomas might exhibit important differences in long-term cure rate despite a similar survival. [METHODS] Using log-rank test, we compared event-free survival (EFS), and the survival of 64 patients with mantle cell lymphoma (MCL), ...
null
null
null
null
null
null
11,920,242
A clinical, molecular and cytogenetic study of 12 cases of human herpesvirus 8 associated primary effusion lymphoma in HIV-infected patients.
The hematology journal : the official journal of the European Haematology Association
Hematol J
2
3
10.1038/sj.thj.6200096
eng
2,001
null
null
null
null
null
[INTRODUCTION] Primary effusion lymphoma is a rare type of B-cell lymphoproliferative disorder which is mainly observed in patients with HIV infection. Lymphomatous cells bridge features of immunoblastic and anaplastic cells with a non-B non-T phenotype and are characterized by the presence of the human herpesvirus 8 g...
null
null
null
null
null
null
11,920,211
Hematopoietic stem cell transplantation in Europe 1998.
The hematology journal : the official journal of the European Haematology Association
Hematol J
1
5
10.1038/sj.thj.6200046
eng
2,000
null
null
null
null
null
[INTRODUCTION] Transplantation of hematopoietic stem cells from blood or bone marrow has become accepted therapy for many diseases. Numbers of transplants have increased significantly and stem cell source, donor type and indications have changed during this decade. Information on these changes is essential for interpre...
null
null
null
null
null
null
11,919,525
Trends in the use and capacity of California's emergency departments, 1990-1999.
Annals of emergency medicine
Ann Emerg Med
39
4
10.1067/mem.2002.122433
eng
2,002
4
null
null
null
null
[STUDY OBJECTIVE] Concerns over the ability of the nation's emergency departments to meet current demands are growing among the public and health care professionals. Data supporting perceptions of inadequate capacity are sparse and conflicting. We describe changes in the use and capacity of California's EDs between 199...
null
1.137
178
Emergency Medicine
Medicine
2,002
11,919,402
Correlation between soluble markers of endothelial dysfunction in patients with renal failure.
American journal of nephrology
Am J Nephrol
22
1
10.1159/000046673
eng
2,002
null
null
null
null
null
[AIM] Damage to the endothelium is an important component of atherosclerosis. It has been suggested to be quantified by measuring plasma markers, such as von Willebrand factor and thrombomodulin and soluble adhesion molecules. We hypothesized there may exist a correlation between the plasma levels of von Willebrand fac...
null
0.578
107
Nephrology
Medicine
2,002
11,919,228
Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
J Clin Oncol
20
7
10.1200/JCO.2002.07.010
eng
2,002
4
1
null
null
null
[PURPOSE] Quality assessment and assurance are important issues in modern health care. For the evaluation of surgical procedures, there are indirect parameters such as complication, recurrence, and survival rates. These parameters are of limited value for the individual surgeon, and there is an obvious need for direct ...
null
4.274
646
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,919,120
Effects of energy-restricted diets containing increased protein on weight loss, resting energy expenditure, and the thermic effect of feeding in type 2 diabetes.
Diabetes care
Diabetes Care
25
4
10.2337/diacare.25.4.652
eng
2,002
4
null
null
null
null
[OBJECTIVE] To determine the effect of a high-protein (HP) diet compared with a low-protein (LP) diet on weight loss, resting energy expenditure (REE), and the thermic effect of food (TEF) in subjects with type 2 diabetes during moderate energy restriction. [RESEARCH DESIGN AND METHODS] In this study, 26 obese subjects...
null
2.924
433
Advanced and Specialized Nursing; Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine; Nursing
2,002
11,917,576
Validation of AutoPap primary screening system sensitivity and high-risk performance.
Acta cytologica
Acta Cytol
46
2
10.1159/000326725
eng
2,002
null
null
null
null
null
[OBJECTIVE] To confirm or deny the reported sensitivity of the AutoPap Primary Screening System (AutoPap) (TriPath Imaging Inc., Burlington, North Carolina, U.S.A) in a moderate-sized laboratory and to determine performance characteristics for the "clinically high risk" (CHR) patient population. [STUDY DESIGN] Archives...
null
0.502
67
Medicine; Histology; Pathology and Forensic Medicine
Medicine
2,002
11,917,055
Parathyroid hormone-independent osteoclastic resorptive bone disease: a new variant of adynamic bone disease in haemodialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Nephrol Dial Transplant
17
4
10.1093/ndt/17.4.620
eng
2,002
4
null
null
null
null
[BACKGROUND] Osteitis fibrosa cystica (OFC) caused by secondary hyperparathyroidism is the pre-eminent form of uraemic osteodystrophy. In recent years, however, new bone abnormalities have been described. Among them adynamic bone disease (ABD) has become a focus of growing interest. Marked suppression of dynamic bone m...
null
0.833
203
Medicine; Nephrology; Transplantation
Medicine
2,002
11,916,620
Mutational analysis of the autoimmune regulator (AIRE) gene in sporadic autoimmune Addison's disease can reveal patients with unidentified autoimmune polyendocrine syndrome type I.
European journal of endocrinology
Eur J Endocrinol
146
4
10.1530/eje.0.1460519
eng
2,002
4
null
null
null
null
[OBJECTIVE] To investigate whether patients with Addison's disease and polyendocrine syndromes have undiagnosed autoimmune polyendocrine syndrome type I (APS I). [MATERIALS AND METHODS] Forty patients with clinical manifestations resembling APS I and with autoantibodies typical of this condition were screened for Norwe...
null
0.875
179
Endocrinology, Diabetes and Metabolism; Medicine; Endocrinology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,916,464
Assessing orientations to learning to teach.
The British journal of educational psychology
Br J Educ Psychol
72
Pt 1
10.1348/000709902158766
eng
2,002
3
null
null
null
null
[BACKGROUND] An important purpose of teacher education is that student teachers develop and change their existing knowledge on learning and teaching. Research on how student teachers variously engage in this process is scarce. In a previous study of 30 student teachers, we identified five different orientations to lear...
null
0.506
120
Education; Developmental and Educational Psychology
Psychology; Social Sciences
2,002
11,916,186
In vitro studies indicate that acid catalysed generation of N-nitrosocompounds from dietary nitrate will be maximal at the gastro-oesophageal junction and cardia.
Scandinavian journal of gastroenterology
Scand J Gastroenterol
37
3
10.1080/003655202317284147
eng
2,002
3
null
null
null
null
[BACKGROUND] Dietary nitrate increases saliva nitrite levels and swallowed saliva is the main source of nitrite entering the acidic stomach. In acidic gastric juice, this nitrite can generate potentially carcinogenic N-nitrosocompounds. However, ascorbic acid secreted by the gastric mucosa can prevent nitrosation by co...
null
0.804
133
Gastroenterology
Medicine
2,002
11,914,593
Effectiveness of the MSC cold cap system in the prevention of chemotherapy-induced alopecia.
Oncology
Oncology
62
2
10.1159/000048253
eng
2,002
null
null
null
null
null
[OBJECTIVE] To study the effectiveness of the MSC cold cap system to prevent chemotherapy-induced alopecia. [METHODS] The system was applied in 83 cancer patients (mean age 49.8 years) undergoing chemotherapy with alopecia-causing agents. Seven patients did not tolerate the system. Seventy-six patients were evaluable f...
null
null
null
null
null
null
11,914,248
High-dose intravascular beta-radiation after de novo stent implantation induces coronary artery spasm.
Circulation
Circulation
105
12
10.1161/01.cir.0000012525.73993.c9
eng
2,002
3
26
null
null
null
[BACKGROUND] Intracoronary brachytherapy is effective in preventing restenosis after coronary interventions. However, in vitro and animal studies have shown that irradiation produces immediate and sustained endothelial dysfunction. This study assesses the clinical relevance of impaired vasomotoric function induced by b...
null
5.233
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,002
11,914,244
Strain rate imaging for assessment of regional myocardial function: results from a clinical model of septal ablation.
Circulation
Circulation
105
12
10.1161/01.cir.0000013423.33806.77
eng
2,002
3
26
null
null
null
[BACKGROUND] Regional myocardial function assessment is essential in the management of coronary artery disease (CAD). Tissue Doppler imaging (TDI) by depicting local myocardial motion can potentially quantify regional myocardial function. Strain rate imaging (SRI) that depicts regional deformation is less susceptible t...
null
5.233
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,002
11,914,153
Is endosonography an effective method for detection and local staging of the ampullary carcinoma? A prospective study.
BMC surgery
BMC Surg
2
null
10.1186/1471-2482-2-1
eng
2,002
3
25
2,002
3
25
[BACKGROUND] The relatively rare carcinoma of the ampulla of Vater is a neoplasia with a good prognosis compared to pancreatic cancer. Preoperative staging is important in planning the most suitable surgical intervention. [AIM] To prospectively evaluate the diagnostic accuracy of Endoscopic Ultrasonography (EUS) in com...
null
0.253
64
Medicine; Surgery
Medicine
2,002
11,913,801
The effects of fenoldopam on renal function in patients undergoing elective aortic surgery.
European journal of anaesthesiology
Eur J Anaesthesiol
19
1
10.1017/s0265021502000054
eng
2,002
1
null
null
null
null
[BACKGROUND AND OBJECTIVE] Postoperative renal impairment is a recognized complication of infrarenal aortic cross-clamping. Our hypothesis was that the renal vasodilating and natriuretic effects of fenoldopam mesylate, a selective dopamine (DA1) agonist, would preserve renal function in patients undergoing elective inf...
null
0.547
94
Anesthesiology and Pain Medicine
Medicine
2,002
11,912,397
Baseline prostatic specific antigen does not predict the outcome of high energy transurethral microwave thermotherapy.
The Journal of urology
J Urol
167
4
null
eng
2,002
4
null
null
null
null
[PURPOSE] We assessed the prognostic value of baseline prostate specific antigen (PSA) for outcome after high energy transurethral thermotherapy in patients with lower urinary tract symptoms. [MATERIAL AND METHODS] Data were collected prospectively in 404 consecutive patients treated with high energy transurethral ther...
null
1.629
291
Urology
Medicine
2,002
11,912,369
The uncertainty of radio frequency treatment of renal cell carcinoma: findings at immediate and delayed nephrectomy.
The Journal of urology
J Urol
167
4
null
eng
2,002
4
null
null
null
null
[PURPOSE] Radio frequency thermal therapy for the ablation of renal cell carcinoma has been reported. Outcomes are usually measured by imaging alone. We have performed ex vivo and in vivo experiments using radio frequency in porcine models in our laboratory. We now report our early experience in the treatment of renal ...
null
1.629
291
Urology
Medicine
2,002
11,910,359
The type II inositol 1,4,5-trisphosphate receptor can trigger Ca2+ waves in rat hepatocytes.
Gastroenterology
Gastroenterology
122
4
10.1053/gast.2002.32363
eng
2,002
4
null
null
null
null
[BACKGROUND AND AIMS] Ca2+ regulates cell functions through signaling patterns such as Ca2+ oscillations and Ca2+ waves. The type I inositol 1,4,5-trisphosphate receptor is thought to support Ca2+ oscillations, whereas the type III inositol 1,4,5-trisphosphate receptor is thought to initiate Ca2+ waves. The role of the...
null
3.536
482
Gastroenterology
Medicine
2,002
11,910,296
Relationship between size at birth and hypertension in a genetically homogeneous population of high birth weight.
Journal of hypertension
J Hypertens
20
4
10.1097/00004872-200204000-00018
eng
2,002
4
null
null
null
null
[OBJECTIVE] To investigate the association between birth size and hypertension within a genetically homogeneous population of high birth weight. [DESIGN] Cohort-study with retrospectively collected data on size at birth. [SUBJECTS AND SETTING] The study included 4601 men and women born 1914-1935 in Reykjavik, Iceland, ...
null
1.441
198
Cardiology and Cardiovascular Medicine; Internal Medicine; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,909,918
Separating depersonalisation and derealisation: the relevance of the "lesion method".
Journal of neurology, neurosurgery, and psychiatry
J Neurol Neurosurg Psychiatry
72
4
10.1136/jnnp.72.4.530
eng
2,002
4
null
null
null
null
[OBJECTIVES] Depersonalisation (DP) and derealisation (DR) are often met with in patients with a wide range of localisable neurological conditions. This suggests that the "lesion method" might be a valid approach to study the neurobiology of DP/DR. However, the fact that anxiety can trigger DP/DR makes it difficult to ...
null
1.238
244
Neurology; Psychiatry and Mental Health; Surgery
Medicine
2,002
11,909,887
Complementary and alternative medicine (CAM) use by older adults: a comparison of self-report and physician chart documentation.
The journals of gerontology. Series A, Biological sciences and medical sciences
J Gerontol A Biol Sci Med Sci
57
4
10.1093/gerona/57.4.m223
eng
2,002
4
null
null
null
null
[BACKGROUND] Older adults are increasingly using complementary and alternative medicine (CAM) dietary supplements and herbal remedies, but may not discuss this with their physicians. When patients do report using CAM, their physicians may not record this information in patient charts. [METHODS] This cross-sectional ana...
null
1.216
230
Aging; Geriatrics and Gerontology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,908,553
Norepinephrine from synovial tyrosine hydroxylase positive cells is a strong indicator of synovial inflammation in rheumatoid arthritis.
The Journal of rheumatology
J Rheumatol
29
3
null
eng
2,002
3
null
null
null
null
[OBJECTIVE] Density of sympathetic nerve fibers in synovial tissue was lower in patients with rheumatoid arthritis (RA) compared to those with osteoarthritis (OA). This was accompanied by norepinephrine (NE) release from synovial tyrosine hydroxylase positive cells (TH+ cells). We investigated the role of TH+ cells and...
null
1.022
201
Rheumatology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,002
11,907,854
Attitudes of female patients regarding oral contraceptives for treatment of acne.
Journal of cutaneous medicine and surgery
J Cutan Med Surg
5
6
10.1007/s10227-001-0023-z
eng
2,001
null
null
null
null
null
[BACKGROUND] Two hormonal agents with contraceptive properties are currently indicated in Canada for treatment of acne. [OBJECTIVE] The purpose of this study was to determine the attitudes and concerns of female patients regarding the use of hormonal agents and oral contraceptives in treatment of acne. [METHODS] A self...
null
0.334
58
Dermatology; Surgery
Medicine
2,001
11,907,844
Human papillomavirus, smoking, and cancer.
Journal of cutaneous medicine and surgery
J Cutan Med Surg
5
4
10.1007/s102270000029
eng
2,001
null
null
2,001
7
18
[BACKGROUND] The effect of smoking on human papillomavirus (HPV) activity and subsequent dysplasia and neoplasia remains controversial. [OBJECTIVE] To determine any reported effects of smoking on either HPV activity or HPV-related dysplasia/cancer using retrospective analysis of the literature from 1966 through 1998 vi...
null
0.334
58
Dermatology; Surgery
Medicine
2,001
11,906,540
Consequences of surveying folate awareness.
Health expectations : an international journal of public participation in health care and health policy
Health Expect
5
1
10.1046/j.1369-6513.2002.00155.x
eng
2,002
3
null
null
null
null
[OBJECTIVES] To assess women's concerns when interviewed about the association between folate and neural tube defects (NTDs) and to determine how this is affected by time, being folate aware, having seen folate promotional material or being pregnant. [DESIGN] As part of a community randomized trial outcomes evaluation,...
null
0.738
100
Public Health, Environmental and Occupational Health
Medicine
2,002
11,905,958
A two-dimensional map and database of soluble nuclear proteins from HepG2 cells as reference for identification of nutrient-regulated transcription factors.
European journal of nutrition
Eur J Nutr
40
4
10.1007/s003940170005
eng
2,001
8
null
null
null
null
[BACKGROUND] Eukaryotic cells of higher organisms are able to regulate gene transcription in response to changes in the supply of nutrients. In hepatocytes, extracellular glucose levels affect transcription of genes that encode enzymes engaged in glycolysis, gluconeogenesis and lipogenesis. While glucose response eleme...
null
0.295
125
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,001
11,905,864
Comparison of thermal spread after ureteral ligation with the Laparo-Sonic ultrasonic shears and the Ligasure system.
Journal of laparoendoscopic & advanced surgical techniques. Part A
J Laparoendosc Adv Surg Tech A
12
1
10.1089/109264202753486957
eng
2,002
2
null
null
null
null
[BACKGROUND AND PURPOSE] The extent of lateral spread of tissue injury is important in the success of a primary anastomosis. We compared the injury produced by the Laparo-sonic Coagulation Shears and the Ligasure system. [MATERIALS AND METHODS] Ureters were harvested from domestic farm pigs and ligated with the Laparo-...
null
null
null
null
null
null
11,905,405
Oxygen therapy for hypercapnic patients with chronic obstructive pulmonary disease and acute respiratory failure: a randomized, controlled pilot study.
Critical care medicine
Crit Care Med
30
1
10.1097/00003246-200201000-00018
eng
2,002
1
null
null
null
null
[OBJECTIVE] To investigate the effect of oxygen therapy on outcome and on symptomatic hypercapnia. [DESIGN] Randomized, controlled, single-blind study. [SETTING] Multidisciplinary intensive care unit of a university teaching hospital. [PATIENTS] Patients admitted with a clinical diagnosis of an acute exacerbation of ch...
null
0.982
315
Critical Care and Intensive Care Medicine
Medicine
2,002
11,904,611
What are pregnant women eating? Nutrient and food group differences by race.
American journal of obstetrics and gynecology
Am J Obstet Gynecol
186
3
10.1067/mob.2002.121078
eng
2,002
3
null
null
null
null
[OBJECTIVE] The purpose of this study was to identify foods that contributed most to nutrient and fiber intake in a sample of pregnant women in North Carolina. [STUDY DESIGN] This was a prospective study of women in the Pregnancy, Infection, and Nutrition Study (n = 2247 women). Dietary information during the second tr...
null
1.509
274
Obstetrics and Gynecology
Medicine
2,002
11,904,607
The preterm prediction study: elevated cervical ferritin levels at 22 to 24 weeks of gestation are associated with spontaneous preterm delivery in asymptomatic women.
American journal of obstetrics and gynecology
Am J Obstet Gynecol
186
3
10.1067/mob.2002.121088
eng
2,002
3
null
null
null
null
[OBJECTIVE] Low serum ferritin levels correlate with low iron stores, whereas high levels are associated with an acute-phase reaction. Our objective was to determine whether elevated levels of ferritin in the genital tract may be a potent marker to identify patients at risk for spontaneous preterm delivery. [STUDY DESI...
null
1.509
274
Obstetrics and Gynecology
Medicine
2,002
11,904,462
Topical mitomycin C and radiation induce conjunctival DNA-polyploidy.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology
Anal Cell Pathol
23
2
10.1155/2001/961735
eng
2,001
null
null
null
null
null
[INTRODUCTION] Atypical cell changes often occur following treatment of premalignant or malignant conjunctival neoplasias with topical mitomycin C (MMC) and/or radiation. These reactive, non-neoplastic alterations of the conjunctival epithelium can be a differential diagnostic problem. Our aim was to investigate change...
null
0.418
32
Pathology and Forensic Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,904,109
Water drinking as a treatment for orthostatic syndromes.
The American journal of medicine
Am J Med
112
5
10.1016/s0002-9343(02)01025-2
eng
2,002
4
1
null
null
null
[PURPOSE] Water drinking increases blood pressure in a substantial proportion of patients who have severe orthostatic hypotension due to autonomic failure. We tested the hypothesis that water drinking can be used as a practical treatment for patients with orthostatic and postprandial hypotension, as well as those with ...
NASA Discipline Regulatory Physiology; Non-NASA Center
1.979
262
Medicine
Medicine
2,002
11,904,026
Characteristics of ventricular shunt malfunctions among patients with neurocysticercosis.
Neurosurgery
Neurosurgery
50
4
10.1097/00006123-200204000-00014
eng
2,002
4
null
null
null
null
[OBJECTIVE] Ventricular shunts used to relieve hydrocephalus among patients with neurocysticercosis have been plagued by high shunt malfunction rates. We examined the characteristics of shunt malfunctions among patients with neurocysticercosis. [METHODS] This is a retrospective chart review of data for 122 patients who...
null
1.568
229
Neurology; Surgery
Medicine
2,002
11,903,689
Effects of quercetin on the heat-induced cytotoxicity of prostate cancer cells.
International journal of urology : official journal of the Japanese Urological Association
Int J Urol
8
11
10.1046/j.1442-2042.2001.00389.x
eng
2,001
11
null
null
null
null
[BACKGROUND] It has been demonstrated that prostate cancer cells are relatively sensitive to heat stress. We have reported that heat treatment at 43 degrees C increases the expression of heat shock protein 70 (hsp70) in prostate cancer cells, leading to apoptosis. Hsp70 is a protein that protects cells against heat dam...
null
0.378
83
Urology
Medicine
2,001
11,903,527
Botulinum toxin type A and EMG: a key to the understanding of chronic tension-type headaches?
Headache
Headache
41
10
10.1046/j.1526-4610.2001.01193.x
eng
2,001
null
null
null
null
null
[BACKGROUND] The pathogenesis of chronic tension-type headache remains unclear, and the role of muscle tension is especially controversial. Botulinum toxin type A, a potent inhibitor of muscle tone, has been used to treat chronic tension-type headache. [OBJECTIVE] To determine whether clinical response to treatment of ...
null
0.85
146
Neurology; Neurology
Medicine; Neuroscience
2,001
11,902,848
Effects of a tailored health promotion program for female blue-collar workers: health works for women.
Preventive medicine
Prev Med
34
3
10.1006/pmed.2001.0988
eng
2,002
3
null
null
null
null
[BACKGROUND] This study assessed the effects of the Health Works for Women (HWW) intervention on improving multiple behaviors including nutrition and physical activity among rural female blue-collar employees in North Carolina. [METHODS] Nine small to mid-size workplaces were randomly assigned to either intervention or...
null
1.289
199
Epidemiology; Public Health, Environmental and Occupational Health
Medicine
2,002
11,902,633
Subjective global assessment of nutrition a useful diagnostic tool for nurses?
EDTNA/ERCA journal (English ed.)
EDTNA ERCA J
27
4
10.1111/j.1755-6686.2001.tb00177.x
eng
2,001
null
null
null
null
null
[UNLABELLED] Malnutrition in maintenance haemodialysis (HD) patients is closely related with morbidity and mortality in this population. [AIM OF THE STUDY] To evaluate feasibility, performance and information given by SGA (subjective global assessment), a semi-quantitative method of nutritional evaluation (based on a m...
null
null
null
null
null
null
11,902,269
Adult long-segment tracheal stenosis attributable to complete tracheal rings masquerading as asthma.
Critical care medicine
Crit Care Med
30
1
10.1097/00003246-200201000-00034
eng
2,002
1
null
null
null
null
[OBJECTIVE] a) To report on an adult patient with congenital long-segment tracheal stenosis from complete tracheal rings complicated by tracheomalacia; b) to highlight the fact that some patients with airway narrowing could be misdiagnosed as having bronchial asthma; and c) to discuss our management with a custom-made ...
null
0.982
315
Critical Care and Intensive Care Medicine
Medicine
2,002
11,902,263
Inhibition of interleukin-6-activated janus kinases/signal transducers and activators of transcription but not mitogen-activated protein kinase signaling in liver of endotoxin-treated rats.
Critical care medicine
Crit Care Med
30
1
10.1097/00003246-200201000-00029
eng
2,002
1
null
null
null
null
[OBJECTIVES] Endotoxin-induced cytokines, such as interleukin-6, mediate systemic inflammatory responses through multiple cellular signaling pathways. Interleukin-6 is also responsible for the synthesis of acute phase proteins. Recent studies have shown that endotoxin can inhibit signal transducers and activators of tr...
null
0.982
315
Critical Care and Intensive Care Medicine
Medicine
2,002
11,902,256
Crystalloid strong ion difference determines metabolic acid-base change during in vitro hemodilution.
Critical care medicine
Crit Care Med
30
1
10.1097/00003246-200201000-00022
eng
2,002
1
null
null
null
null
[OBJECTIVES] To determine the relationship between the strong ion difference (SID) of a diluting crystalloid and its metabolic acid-base effects on in vitro blood dilution. [DESIGN] Prospective in vitro study. [SETTING] University research laboratory. [SUBJECTS] Normal human blood. [INTERVENTIONS] Three solutions were ...
null
0.982
315
Critical Care and Intensive Care Medicine
Medicine
2,002
11,901,034
Successful treatment of amiodarone-induced thyrotoxicosis.
Circulation
Circulation
105
11
null
eng
2,002
3
19
null
null
null
[BACKGROUND] Amiodarone-induced thyrotoxicosis (AIT) is a difficult management problem about which there are little published data. We examined whether continuing amiodarone or differentiating AIT into 2 subtypes affected outcome. [METHODS AND RESULTS] The type and duration of antithyroid treatment and response were re...
null
5.233
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,002
11,900,231
A prospective study of pulmonary function in patients treated with paclitaxel and carboplatin.
Cancer
Cancer
94
2
10.1002/cncr.10182
eng
2,002
1
15
null
null
null
[BACKGROUND] Adverse effects of paclitaxel and carboplatin have been well described; however, pulmonary toxicity after patients receive this regimen has not been investigated extensively. [METHODS] To clarify this issue, 33 consecutive patients who were treated with paclitaxel and carboplatin underwent prospective eval...
null
1.595
349
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,900,230
Percutaneous tumor ablation with radiofrequency.
Cancer
Cancer
94
2
10.1002/cncr.10234
eng
2,002
1
15
null
null
null
[BACKGROUND] Radiofrequency thermal ablation (RFA) is a new minimally invasive treatment for localized cancer. Minimally invasive surgical options require less resources, time, recovery, and cost, and often offer reduced morbidity and mortality, compared with more invasive methods. To be useful, image-guided, minimally...
null
1.595
349
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,898,002
Expression and function of histamine receptors 1 and 2 on human monocyte-derived dendritic cells.
The Journal of allergy and clinical immunology
J Allergy Clin Immunol
109
3
10.1067/mai.2002.121944
eng
2,002
3
null
null
null
null
[BACKGROUND] Histamine is a well-known mediator of inflammatory and allergic reactions and has immunomodulatory capacities. There is increasing evidence that dendritic cells as professional antigen-presenting cells play a major role in the development of allergic reactions. However, a possible link between histamine an...
null
2.506
350
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,002
11,897,510
Intraperitoneal photodynamic therapy in the Fischer 344 rat using 5-aminolevulinic acid and violet laser light: a toxicity study.
Journal of photochemistry and photobiology. B, Biology
J Photochem Photobiol B
66
2
10.1016/s1011-1344(01)00249-4
eng
2,002
3
null
null
null
null
[OBJECTIVE] Our study was designed to investigate 5-aminolevulinic acid (ALA) as a candidate for intraperitoneal photodynamic therapy (IP-PDT). The toxicity of IP-PDT and the effects of IP-PDT on abdominal and pelvic organs, particularly the small intestine, were investigated after ALA administration and illumination w...
null
null
null
null
null
null
11,896,111
Predictors of smoking initiation and cessation among childhood cancer survivors: a report from the childhood cancer survivor study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
J Clin Oncol
20
6
10.1200/JCO.2002.20.6.1608
eng
2,002
3
15
null
null
null
[PURPOSE] To examine the determinants of smoking behavior among participants in the Childhood Cancer Survivors Study (CCSS). [METHODS] This retrospective cohort survey study was conducted among 9,709 childhood cancer survivors. Main outcomes included smoking initiation and cessation. [RESULTS] Twenty-eight percent of p...
null
4.274
646
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,896,103
Overexpression of c-met as a prognostic indicator for transitional cell carcinoma of the urinary bladder: a comparison with p53 nuclear accumulation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
J Clin Oncol
20
6
10.1200/JCO.2002.20.6.1544
eng
2,002
3
15
null
null
null
[PURPOSE] The c-met proto-oncogene encodes a receptor tyrosine kinase (Met) and has been shown to play a role in oncogenesis. Given that high titers of hepatocyte growth factor, the specific ligand for Met, are excreted in the urine and tend to reflect disease activity of bladder cancer, we performed this study to exam...
null
4.274
646
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,896,100
Randomized, open-label, phase III study of a 28-day oral regimen of eniluracil plus fluorouracil versus intravenous fluorouracil plus leucovorin as first-line therapy in patients with metastatic/advanced colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
J Clin Oncol
20
6
10.1200/JCO.2002.20.6.1519
eng
2,002
3
15
null
null
null
[PURPOSE] To compare the efficacy and tolerability of eniluracil (EU)/fluorouracil (5-FU) with that of 5-FU/leucovorin (LV) as first-line therapy for patients with metastatic/advanced colorectal cancer. [PATIENTS AND METHODS] This multicenter, randomized, open-label, phase III study (FUMA3008) conducted in the United S...
null
4.274
646
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
11,895,482
Identification of activity-regulated proteins in the postsynaptic density fraction.
Genes to cells : devoted to molecular & cellular mechanisms
Genes Cells
7
2
10.1046/j.1356-9597.2001.00505.x
eng
2,002
2
null
null
null
null
[BACKGROUND] The postsynaptic density (PSD) at synapses is a specialized submembranous structure where neurotransmitter receptors are linked to cytoskeleton and signalling molecules. Activity-dependent dynamic change in the components of the PSD is a mechanism of synaptic plasticity. Identification of the PSD proteins ...
null
null
null
null
null
null
11,895,286
Comparison of platelet-rich plasma, bovine porous bone mineral, and guided tissue regeneration versus platelet-rich plasma and bovine porous bone mineral in the treatment of intrabony defects: a reentry study.
Journal of periodontology
J Periodontol
73
2
10.1902/jop.2002.73.2.198
eng
2,002
2
null
null
null
null
[BACKGROUND] A combination of platelet-rich plasma (PRP), bovine porous bone mineral (BPBM), and guided tissue regeneration (GTR) has been shown to be effective in promoting reduction in probing depth, gain in clinical attachment, and defect fill in intrabony periodontal lesions. The individual role played by PRP, BPBM...
null
0.932
186
Periodontics
Dentistry
2,002
11,894,837
Insufficiency fractures in patients with chronic inflammatory joint diseases.
Clinical and experimental rheumatology
Clin Exp Rheumatol
20
1
null
eng
2,002
null
null
null
null
null
[OBJECTIVE] To describe the typical sites of stress fractures in the lower extremities and pelvis in rheumatoid patients (rheumatoid arthritis, juvenile chronic arthritis, psoriatic arthritis, ankylosing spondylitis). [METHODS] Thirty-three patients with 52 stress fractures [mean age 44 years (range 11-73)] were studie...
null
0.548
112
Immunology and Allergy; Rheumatology; Immunology
Immunology and Microbiology; Medicine
2,002
11,893,445
Effect of background noise on perception of English speech for Japanese listeners.
Auris, nasus, larynx
Auris Nasus Larynx
29
2
10.1016/s0385-8146(01)00133-x
eng
2,002
4
null
null
null
null
[OBJECTIVES] To avoid the accidents induced by confusions of non-native speech perception in the presence of noise at work, this study examined the effect of background noise on the discrimination of English speech for Japanese listeners. [METHODS] Normal hearing Japanese subjects, who have English learning experience ...
null
0.337
62
Medicine; Otorhinolaryngology; Surgery
Medicine
2,002
11,892,711
The role of peroxynitrite in cyclooxygenase-2 expression of rheumatoid synovium.
Clinical and experimental rheumatology
Clin Exp Rheumatol
20
1
null
eng
2,002
null
null
null
null
null
[OBJECTIVE] Reactive oxygen intermediates play an important role in the inflammatory processes of rheumatoid arthritis. Cyclooxygenase-2 is an inducible form of an enzyme involved in prostanoid biosynthesis. This study linked peroxynitrite (ONOO-) to the signaling pathways that induce COX-2. [RESULTS] Exposure of rheum...
null
0.548
112
Immunology and Allergy; Rheumatology; Immunology
Immunology and Microbiology; Medicine
2,002
11,892,706
Upper gastrointestinal tolerability of celecoxib compared with diclofenac in the treatment of osteoarthritis and rheumatoid arthritis.
Clinical and experimental rheumatology
Clin Exp Rheumatol
20
1
null
eng
2,002
null
null
null
null
null
[OBJECTIVE] To compare the upper gastrointestinal (UGI) tolerability of celecoxib (a cyclooxygenase-2 specific inhibitor) and diclofenac using data from three randomised, double-blind clinical trials in osteoarthritis (OA) and rheumatoid arthritis (RA). [METHODS] Patients in two OA studies received either celecoxib 100...
null
0.548
112
Immunology and Allergy; Rheumatology; Immunology
Immunology and Microbiology; Medicine
2,002
11,892,542
Factors influencing the access to prenatal care by Hispanic pregnant women.
Journal of the American Academy of Nurse Practitioners
J Am Acad Nurse Pract
14
2
10.1111/j.1745-7599.2002.tb00097.x
eng
2,002
2
null
null
null
null
[PURPOSE] To explore factors influencing the access to prenatal care among Hispanic pregnant women living in the United States. [DATA SOURCES] A convenience sample of 46 Hispanic migrant pregnant women was interviewed over a 12-month period using a set of five open-ended questions. [CONCLUSIONS] The ability of the heal...
null
0.127
54
Nursing
Nursing
2,002
11,891,164
Determining the predictors of internal medicine residency accreditation: what they do (not what they say).
Academic medicine : journal of the Association of American Medical Colleges
Acad Med
77
3
10.1097/00001888-200203000-00014
eng
2,002
3
null
null
null
null
[PURPOSE] The Accreditation Council for Graduate Medical Education and the Residency Review Committee for Internal Medicine (RRC-IM) evaluate internal medicine residency programs using a list of 301 program requirements. The authors investigated which requirements, program demographics, and site-visitor characteristics...
null
0.78
199
Education; Medicine
Medicine; Social Sciences
2,002
11,890,438
Comparison of propolis skin cream to silver sulfadiazine: a naturopathic alternative to antibiotics in treatment of minor burns.
Journal of alternative and complementary medicine (New York, N.Y.)
J Altern Complement Med
8
1
10.1089/107555302753507203
eng
2,002
2
null
null
null
null
[BACKGROUND] Propolis, a naturopathic substance derived from bees wax extract, has recently been praised for its antimicrobial, anti-inflammatory, and cicatrization-enhancing properties. [OBJECTIVE] In our study, we compare these properties in a high-grade Brazilian propolis skin cream directly with silver sulfadiazene...
null
0.568
0
Complementary and Alternative Medicine
Medicine
2,002
11,890,433
The effect of immunization with killed tumor cells, with/without feeding of Echinacea purpurea in an erythroleukemic mouse model.
Journal of alternative and complementary medicine (New York, N.Y.)
J Altern Complement Med
8
1
10.1089/107555302753507177
eng
2,002
2
null
null
null
null
[OBJECTIVE] Tumor amelioration via vaccination/immunization is a practice for which considerable experimental and clinical support is growing. Combination therapies have proven to be more beneficial than treatment with single agents. We hypothesized that immunization of mice with killed erythroleukemia cells prior to t...
null
0.568
0
Complementary and Alternative Medicine
Medicine
2,002
11,890,369
Plasma C-reactive protein predicts left ventricular remodeling and function after a first acute anterior wall myocardial infarction treated with coronary angioplasty: comparison with brain natriuretic peptide.
Clinical cardiology
Clin Cardiol
25
3
10.1002/clc.4960250306
eng
2,002
3
null
null
null
null
[BACKGROUND] C-reactive protein (CRP) directly participates in the myocardial injury of acute myocardial infarction (MI). Although high plasma CRP levels in the acute phase strongly indicate a poor early clinical outcome of patients with MI, the impact of CRP levels on late left ventricular (LV) function and remodeling...
null
0.672
89
Cardiology and Cardiovascular Medicine; Medicine
Medicine
2,002
11,889,622
Occurrence and therapy of space-occupying cystic lesions after brain tumor surgery.
Zentralblatt fur Neurochirurgie
Zentralbl Neurochir
62
3
10.1055/s-2001-21792
eng
2,001
null
null
null
null
null
[OBJECTIVES] Space-occupying cystic lesions may develop in a variable time after resection of particular intracranial tumors, representing a small amount of complications of these procedures. We present our experience with the development and operative treatment of such postoperative cystic lesions in order to identify...
null
null
null
null
null
null
11,889,502
Pharmacological manipulation of brain galaninergic system and sexual behavior in male mice.
Psychopharmacology
Psychopharmacology (Berl)
160
3
10.1007/s00213-001-0992-z
eng
2,002
3
null
2,002
1
31
[RATIONALE] Available data suggest a complex role for the brain galaninergic system in male sexual behavior; however, the results so far obtained in animals with either galanin or galanin antagonists are conflicting. [OBJECTIVE] To define the better influence of galanin on male sexual behavior by studying, in mice, (i)...
null
1.66
218
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,002